Open-mkt buys · 90d
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0 trades · 0 insiders
Open-mkt sales · 90d
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0 trades · 0 insiders
Net · 90d
$0
Insiders on file
23
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Ferber Celeste | SVP, GC and Secretary | 9 | $0 | $36.2K | 2020-09-15 |
| Templeman Blaine | See Remarks | 29 | $0 | $348.0K | 2020-09-15 |
| ISAACS STEPHEN T | President and CEO | 147 | $0 | $9.87M | 2020-09-15 |
| Nuyten Dimitry SA | Chief Medical Officer | 4 | $0 | $9.0K | 2020-08-07 |
| Haghighat Ross | Director | 43 | $0 | $109.9K | 2020-06-01 |
| Kachioff William G | Interim CFO | 1 | $0 | $0 | 2020-06-01 |
| OBrien Stephanie Monaghan | Director | 8 | $57.8K | $0 | 2020-05-05 |
| Greenman William Mariner | Director | 12 | $51.0K | $92.0K | 2020-05-05 |
| Mack David Henry | Director | 3 | $0 | $0 | 2020-05-05 |
| KARBE FRANK | Director | 3 | $0 | $0 | 2020-05-05 |
| SHERWIN STEPHEN A | Director | 6 | $0 | $0 | 2020-05-05 |
| van Elsas Andrea | Chief Scientific Officer | 25 | $0 | $536.5K | 2020-02-25 |
| WELCH JAMES H | See Remarks | 1 | $0 | $0 | 2019-07-15 |
| Lew Jennifer | Sr. Vice President of Finance | 73 | $34.0K | $1.59M | 2019-05-01 |
| Sacks Natalie | Chief Medical Officer | 10 | $0 | $109.0K | 2018-09-13 |
| Chan Gerald | Director | 4 | $0 | $0 | 2018-06-06 |
| MCCORMICK FRANK | Director | 4 | $0 | $0 | 2018-06-06 |
| SCHAFER GREGORY W | Chief Operating Officer | 80 | $0 | $5.09M | 2018-01-25 |
| Brockstedt Dirk G. | Sr. VP of Research and Dev. | 89 | $0 | $3.61M | 2017-12-29 |
| Dubensky Thomas W. | Chief Scientific Officer | 105 | $0 | $7.34M | 2017-08-11 |
| Morningside Venture (VI) Investments Ltd | 10% Owner | 21 | $7.50M | $0 | 2016-02-18 |
| Ultimate Keen Ltd | 10% Owner | 4 | $0 | $0 | 2015-04-20 |
| Rogers John E. and Lois A. | 10% Owner | 51 | $2.80M | $0 | 2015-04-20 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Ferber Celeste | SVP, GC and Secretary | S Sale | 2020-09-15 | 2020-09-17 | 2,396 | $2.39 | $5.7K | 38,687 | SEC↗ |
| Templeman Blaine | Chief Legal Officer | S Sale | 2020-09-15 | 2020-09-17 | 12,369 | $2.39 | $29.6K | 121,916 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2020-09-15 | 2020-09-17 | 32,481 | $2.39 | $77.6K | 279,166 | SEC↗ |
| Ferber Celeste | SVP, GC and Secretary | S Sale | 2020-08-07 | 2020-08-11 | 7,951 | $2.55 | $20.3K | 41,083 | SEC↗ |
| Templeman Blaine | Chief Legal Officer | S Sale | 2020-08-07 | 2020-08-11 | 7,951 | $2.55 | $20.3K | 134,285 | SEC↗ |
| Nuyten Dimitry SA | Chief Medical Officer | S Sale | 2020-08-07 | 2020-08-11 | 3,538 | $2.55 | $9.0K | 8,462 | SEC↗ |
| Templeman Blaine | Chief Legal Officer | A Award | 2020-06-01 | 2020-06-03 | 22,500 | — | $0 | 142,236 | SEC↗ |
| Nuyten Dimitry SA | Chief Medical Officer | A Award | 2020-06-01 | 2020-06-03 | 10,000 | — | $0 | 12,000 | SEC↗ |
| Haghighat Ross | Director | A Award | 2020-06-01 | 2020-06-03 | 34,124 | — | $0 | 121,246 | SEC↗ |
| Ferber Celeste | SVP, GC and Secretary | A Award | 2020-06-01 | 2020-06-03 | 22,500 | — | $0 | 49,034 | SEC↗ |
| Kachioff William G | Interim CFO | A Award | 2020-06-01 | 2020-06-03 | 10,000 | — | $0 | 10,000 | SEC↗ |
| OBrien Stephanie Monaghan | Director | A Award deriv | 2020-05-05 | 2020-05-28 | 30,000 | — | $0 | 30,000 | SEC↗ |
| SHERWIN STEPHEN A | Director | A Award deriv | 2020-05-05 | 2020-05-28 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Greenman William Mariner | Director | A Award deriv | 2020-05-05 | 2020-05-28 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Haghighat Ross | Director | A Award deriv | 2020-05-05 | 2020-05-28 | 30,000 | — | $0 | 30,000 | SEC↗ |
| KARBE FRANK | Director | A Award deriv | 2020-05-05 | 2020-05-28 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Mack David Henry | Director | A Award deriv | 2020-05-05 | 2020-05-28 | 30,000 | — | $0 | 30,000 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2020-03-18 | 2020-03-20 | 21,618 | — | $0 | 0 | SEC↗ |
| Greenman William Mariner | Director | M Exercise deriv | 2020-03-18 | 2020-03-20 | 4,566 | — | $0 | 0 | SEC↗ |
| Greenman William Mariner | Director | M Exercise deriv | 2020-03-18 | 2020-03-20 | 2,458 | — | $0 | 0 | SEC↗ |
| Greenman William Mariner | Director | M Exercise deriv | 2020-03-18 | 2020-03-20 | 12,811 | — | $0 | 0 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2020-03-18 | 2020-03-20 | 21,618 | $0.45 | $9.7K | 311,647 | SEC↗ |
| Greenman William Mariner | Director | M Exercise | 2020-03-18 | 2020-03-20 | 19,835 | $0.45 | $8.9K | 19,835 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2020-02-25 | 2020-02-26 | 6,823 | $3.51 | $23.9K | 438,367 | SEC↗ |
| Ferber Celeste | SVP, GC and Secretary | A Award deriv | 2020-02-21 | 2020-02-24 | 250,000 | — | $0 | 250,000 | SEC↗ |
| Nuyten Dimitry SA | Chief Medical Officer | A Award deriv | 2020-02-21 | 2020-02-24 | 250,000 | — | $0 | 250,000 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | A Award deriv | 2020-02-21 | 2020-02-24 | 850,000 | — | $0 | 850,000 | SEC↗ |
| Templeman Blaine | Chief Legal Officer | A Award deriv | 2020-02-21 | 2020-02-24 | 250,000 | — | $0 | 250,000 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | A Award deriv | 2020-02-21 | 2020-02-24 | 250,000 | — | $0 | 250,000 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | A Award deriv | 2020-02-21 | 2020-02-24 | 250,000 | — | $0 | 250,000 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2020-01-03 | 2020-01-06 | 73,311 | $1.19 | $87.2K | 445,190 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2019-12-12 | 2019-12-16 | 5,897 | $1.16 | $6.8K | 290,029 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2019-12-12 | 2019-12-16 | 2,192 | $1.16 | $2.5K | 518,501 | SEC↗ |
| Ferber Celeste | SVP, GC and Secretary | S Sale | 2019-12-12 | 2019-12-16 | 408 | $1.16 | $473 | 26,534 | SEC↗ |
| Templeman Blaine | Chief Legal Officer | S Sale | 2019-12-12 | 2019-12-16 | 1,264 | $1.16 | $1.5K | 117,736 | SEC↗ |
| Haghighat Ross | Director | M Exercise deriv | 2019-09-16 | 2019-09-18 | 18,000 | — | $0 | 0 | SEC↗ |
| Haghighat Ross | Director | M Exercise deriv | 2019-09-16 | 2019-09-18 | 21,451 | — | $0 | 0 | SEC↗ |
| Haghighat Ross | Director | M Exercise deriv | 2019-09-16 | 2019-09-18 | 4,566 | — | $0 | 0 | SEC↗ |
| Haghighat Ross | Director | M Exercise deriv | 2019-09-16 | 2019-09-18 | 9,063 | — | $0 | 0 | SEC↗ |
| Haghighat Ross | Director | M Exercise deriv | 2019-09-16 | 2019-09-18 | 2,459 | — | $0 | 0 | SEC↗ |
| Haghighat Ross | Director | M Exercise | 2019-09-16 | 2019-09-18 | 18,000 | $1.00 | $18.0K | 49,583 | SEC↗ |
| Haghighat Ross | Director | M Exercise | 2019-09-16 | 2019-09-18 | 21,451 | $0.45 | $9.7K | 71,034 | SEC↗ |
| Haghighat Ross | Director | M Exercise | 2019-09-16 | 2019-09-18 | 4,566 | $0.45 | $2.1K | 75,600 | SEC↗ |
| Haghighat Ross | Director | M Exercise | 2019-09-16 | 2019-09-18 | 9,063 | $0.52 | $4.7K | 87,122 | SEC↗ |
| Haghighat Ross | Director | M Exercise | 2019-09-16 | 2019-09-18 | 2,459 | $0.45 | $1.1K | 78,059 | SEC↗ |
| Templeman Blaine | Chief Legal Officer | S Sale | 2019-09-13 | 2019-09-17 | 5,888 | $1.31 | $7.7K | 117,000 | SEC↗ |
| Templeman Blaine | Chief Legal Officer | S Sale | 2019-09-13 | 2019-09-17 | 6,990 | $1.31 | $9.2K | 122,888 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2019-09-13 | 2019-09-17 | 17,959 | $1.31 | $23.5K | 521,327 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2019-09-13 | 2019-09-17 | 634 | $1.31 | $831 | 520,693 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2019-09-13 | 2019-09-17 | 31,098 | $1.31 | $40.7K | 295,926 | SEC↗ |
| Ferber Celeste | SVP, GC and Secretary | S Sale | 2019-09-13 | 2019-09-17 | 1,102 | $1.31 | $1.4K | 26,942 | SEC↗ |
| Ferber Celeste | SVP, GC and Secretary | S Sale | 2019-09-13 | 2019-09-17 | 1,392 | $1.31 | $1.8K | 28,044 | SEC↗ |
| WELCH JAMES H | See Remarks | A Award deriv | 2019-07-15 | 2019-07-15 | 200,000 | — | $0 | 200,000 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | A Award | 2019-06-26 | 2019-06-28 | 275,000 | — | $0 | 539,286 | SEC↗ |
| Ferber Celeste | SVP, GC and Secretary | S Sale | 2019-05-20 | 2019-05-22 | 2,000 | $3.21 | $6.4K | 29,436 | SEC↗ |
| Mack David Henry | Director | A Award deriv | 2019-05-14 | 2019-05-15 | 30,000 | — | $0 | 30,000 | SEC↗ |
| OBrien Stephanie Monaghan | Director | A Award deriv | 2019-05-14 | 2019-05-15 | 30,000 | — | $0 | 30,000 | SEC↗ |
| SHERWIN STEPHEN A | Director | A Award deriv | 2019-05-14 | 2019-05-15 | 30,000 | — | $0 | 30,000 | SEC↗ |
| KARBE FRANK | Director | A Award deriv | 2019-05-14 | 2019-05-15 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Greenman William Mariner | Director | A Award deriv | 2019-05-14 | 2019-05-15 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Haghighat Ross | Director | A Award deriv | 2019-05-14 | 2019-05-15 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Nuyten Dimitry SA | Chief Medical Officer | A Award deriv | 2019-05-13 | 2019-05-15 | 400,000 | — | $0 | 400,000 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | M Exercise deriv | 2019-05-01 | 2019-05-03 | 2,232 | — | $0 | 22,320 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | M Exercise deriv | 2019-05-01 | 2019-05-03 | 12,144 | — | $0 | 121,440 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | M Exercise deriv | 2019-05-01 | 2019-05-03 | 4,226 | — | $0 | 42,258 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | M Exercise | 2019-05-01 | 2019-05-03 | 2,232 | $1.00 | $2.2K | 137,387 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | S Sale | 2019-05-01 | 2019-05-03 | 2,232 | $4.20 | $9.4K | 135,155 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | M Exercise | 2019-05-01 | 2019-05-03 | 12,144 | $1.45 | $17.6K | 147,299 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | S Sale | 2019-05-01 | 2019-05-03 | 12,144 | $4.20 | $51.0K | 135,155 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | S Sale | 2019-05-01 | 2019-05-03 | 4,226 | $4.20 | $17.7K | 135,155 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | M Exercise | 2019-05-01 | 2019-05-03 | 4,226 | $0.82 | $3.5K | 139,381 | SEC↗ |
| KARBE FRANK | Director | A Award deriv | 2019-04-18 | 2019-04-19 | 60,000 | — | $0 | 60,000 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | M Exercise deriv | 2019-04-08 | 2019-04-10 | 4,225 | — | $0 | 46,484 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | M Exercise deriv | 2019-04-08 | 2019-04-10 | 2,232 | — | $0 | 24,552 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | M Exercise deriv | 2019-04-08 | 2019-04-10 | 12,144 | — | $0 | 133,584 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | S Sale | 2019-04-08 | 2019-04-10 | 4,225 | $4.08 | $17.2K | 135,155 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | S Sale | 2019-04-08 | 2019-04-10 | 2,232 | $4.07 | $9.1K | 135,155 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | M Exercise | 2019-04-08 | 2019-04-10 | 2,232 | $1.00 | $2.2K | 137,387 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | M Exercise | 2019-04-08 | 2019-04-10 | 4,225 | $0.82 | $3.5K | 139,380 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | M Exercise | 2019-04-08 | 2019-04-10 | 12,144 | $1.45 | $17.6K | 147,299 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | S Sale | 2019-04-08 | 2019-04-10 | 12,144 | $4.07 | $49.4K | 135,155 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2019-03-19 | 2019-03-21 | 6,081 | $3.96 | $24.1K | 239,557 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2019-02-26 | 2019-02-27 | 6,844 | $4.25 | $29.1K | 245,638 | SEC↗ |
| Mack David Henry | Director | A Award deriv | 2019-02-19 | 2019-02-21 | 40,000 | — | $0 | 40,000 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | A Award deriv | 2019-02-19 | 2019-02-21 | 900,000 | — | $0 | 900,000 | SEC↗ |
| Templeman Blaine | See Remarks | A Award deriv | 2019-02-19 | 2019-02-21 | 400,000 | — | $0 | 400,000 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | A Award deriv | 2019-02-19 | 2019-02-21 | 400,000 | — | $0 | 400,000 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | A Award deriv | 2019-02-19 | 2019-02-21 | 400,000 | — | $0 | 400,000 | SEC↗ |
| Ferber Celeste | SVP, GC and Secretary | A Award deriv | 2019-02-19 | 2019-02-21 | 300,000 | — | $0 | 300,000 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2018-12-28 | 2018-12-31 | 1,907 | $2.57 | $4.9K | 252,482 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2018-12-12 | 2018-12-14 | 2,171 | $2.93 | $6.4K | 254,389 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2018-12-12 | 2018-12-14 | 5,829 | $2.93 | $17.1K | 327,024 | SEC↗ |
| Templeman Blaine | Chief Legal Officer | S Sale | 2018-12-12 | 2018-12-14 | 1,241 | $2.93 | $3.6K | 129,878 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | S Sale | 2018-12-12 | 2018-12-14 | 1,035 | $2.93 | $3.0K | 135,155 | SEC↗ |
| Templeman Blaine | Chief Legal Officer | S Sale | 2018-11-20 | 2018-11-20 | 843 | $2.91 | $2.5K | 131,119 | SEC↗ |
| Templeman Blaine | Chief Legal Officer | S Sale | 2018-09-24 | 2018-09-25 | 10,262 | $5.81 | $59.6K | 131,119 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2018-09-24 | 2018-09-25 | 7,726 | $5.83 | $45.0K | 256,560 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2018-09-13 | 2018-09-14 | 24,143 | $6.50 | $156.9K | 332,853 | SEC↗ |
| Sacks Natalie | Chief Medical Officer | S Sale | 2018-09-13 | 2018-09-14 | 3,028 | $6.50 | $19.7K | 173,720 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | S Sale | 2018-09-13 | 2018-09-14 | 5,623 | $6.50 | $36.5K | 136,190 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2018-09-13 | 2018-09-14 | 9,754 | $6.50 | $63.4K | 264,286 | SEC↗ |
| Templeman Blaine | Executive VP, General Counse | S Sale | 2018-09-13 | 2018-09-14 | 6,056 | $6.50 | $39.4K | 141,381 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | A Award | 2018-09-12 | 2018-09-14 | 151,250 | — | $0 | 356,996 | SEC↗ |
| Sacks Natalie | Chief Medical Officer | A Award | 2018-09-12 | 2018-09-14 | 87,200 | — | $0 | 176,748 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | A Award | 2018-09-12 | 2018-09-14 | 67,825 | — | $0 | 141,813 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | A Award | 2018-09-12 | 2018-09-14 | 67,825 | — | $0 | 274,040 | SEC↗ |
| Templeman Blaine | Executive VP, General Counse | A Award | 2018-09-12 | 2018-09-14 | 77,500 | — | $0 | 147,437 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2018-09-06 | 2018-09-06 | 46,987 | — | $0 | 763,907 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2018-09-06 | 2018-09-06 | 46,987 | $1.00 | $47.0K | 252,733 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2018-09-06 | 2018-09-06 | 46,987 | $7.92 | $372.1K | 205,746 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2018-09-05 | 2018-09-06 | 15,585 | — | $0 | 810,894 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2018-09-05 | 2018-09-06 | 15,585 | $7.90 | $123.1K | 205,746 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2018-09-05 | 2018-09-06 | 15,585 | $1.00 | $15.6K | 221,331 | SEC↗ |
| Sacks Natalie | Chief Medical Officer | S Sale | 2018-09-04 | 2018-09-06 | 4,504 | $7.13 | $32.1K | 89,548 | SEC↗ |
| Haghighat Ross | Director | J Other | 2018-08-29 | 2018-08-31 | 50,297 | — | $0 | 31,583 | SEC↗ |
| Haghighat Ross | Director | J Other | 2018-08-29 | 2018-08-31 | 50,297 | — | $0 | 107,005 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2018-07-17 | 2018-07-19 | 10,454 | $6.96 | $72.8K | 206,215 | SEC↗ |
| Chan Gerald | Director | A Award deriv | 2018-06-06 | 2018-06-08 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Greenman William Mariner | Director | A Award deriv | 2018-06-06 | 2018-06-08 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Haghighat Ross | Director | A Award deriv | 2018-06-06 | 2018-06-08 | 20,000 | — | $0 | 20,000 | SEC↗ |
| MCCORMICK FRANK | Director | A Award deriv | 2018-06-06 | 2018-06-08 | 20,000 | — | $0 | 20,000 | SEC↗ |
| OBrien Stephanie Monaghan | Director | A Award deriv | 2018-06-06 | 2018-06-08 | 20,000 | — | $0 | 20,000 | SEC↗ |
| SHERWIN STEPHEN A | Director | A Award deriv | 2018-06-06 | 2018-06-08 | 20,000 | — | $0 | 20,000 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2018-06-01 | 2018-06-05 | 40,000 | — | $0 | 826,479 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2018-06-01 | 2018-06-05 | 40,000 | $1.00 | $40.0K | 245,746 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2018-06-01 | 2018-06-05 | 40,000 | $8.68 | $347.2K | 205,746 | SEC↗ |
| Templeman Blaine | Chief Legal Officer | S Sale | 2018-05-17 | 2018-05-21 | 2,000 | $8.15 | $16.3K | 69,937 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2018-05-09 | 2018-05-11 | 34,312 | — | $0 | 866,479 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2018-05-09 | 2018-05-11 | 5,688 | — | $0 | 0 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2018-05-09 | 2018-05-11 | 5,688 | $0.82 | $4.7K | 211,434 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2018-05-09 | 2018-05-11 | 40,000 | $8.01 | $320.4K | 205,746 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2018-05-09 | 2018-05-11 | 34,312 | $1.00 | $34.3K | 245,746 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2018-04-02 | 2018-04-04 | 40,000 | — | $0 | 5,688 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2018-04-02 | 2018-04-04 | 40,000 | $0.82 | $32.8K | 245,746 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2018-04-02 | 2018-04-04 | 40,000 | $8.91 | $356.4K | 205,746 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2018-03-09 | 2018-03-09 | 15,676 | — | $0 | 0 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2018-03-09 | 2018-03-09 | 19,672 | — | $0 | 0 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2018-03-09 | 2018-03-09 | 6,155 | — | $0 | 45,688 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2018-03-09 | 2018-03-09 | 4,914 | — | $0 | 0 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2018-03-09 | 2018-03-09 | 4,914 | $0.45 | $2.2K | 246,008 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2018-03-09 | 2018-03-09 | 20,605 | $9.01 | $185.7K | 205,746 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2018-03-09 | 2018-03-09 | 25,812 | $8.59 | $221.7K | 226,351 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2018-03-09 | 2018-03-09 | 6,155 | $0.82 | $5.0K | 252,163 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2018-03-09 | 2018-03-09 | 19,672 | $0.45 | $8.9K | 241,094 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2018-03-09 | 2018-03-09 | 15,676 | $0.45 | $7.1K | 221,422 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2018-03-08 | 2018-03-09 | 25,634 | — | $0 | 15,676 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2018-03-08 | 2018-03-09 | 25,634 | $0.45 | $11.5K | 231,380 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2018-03-08 | 2018-03-09 | 25,634 | $7.95 | $203.8K | 205,746 | SEC↗ |
| Templeman Blaine | Executive VP, General Counse | A Award deriv | 2018-02-28 | 2018-02-12 | 155,000 | — | $0 | 155,000 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2018-02-26 | 2018-02-27 | 6,874 | $6.48 | $44.5K | 216,669 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | A Award deriv | 2018-02-08 | 2018-02-12 | 135,650 | — | $0 | 135,650 | SEC↗ |
| Lew Jennifer | Chief Financial Officer | A Award deriv | 2018-02-08 | 2018-02-12 | 135,650 | — | $0 | 135,650 | SEC↗ |
| Sacks Natalie | Chief Medical Officer | A Award deriv | 2018-02-08 | 2018-02-12 | 174,400 | — | $0 | 174,400 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | A Award deriv | 2018-02-08 | 2018-02-12 | 376,250 | — | $0 | 376,250 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2018-01-25 | 2018-01-26 | 60,000 | — | $0 | 87,322 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | X Exercise deriv | 2018-01-25 | 2018-01-26 | 3,317 | — | $0 | 0 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | X Exercise | 2018-01-25 | 2018-01-26 | 3,317 | $0.01 | $33 | 254,062 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2018-01-25 | 2018-01-26 | 60,000 | $0.82 | $49.2K | 250,745 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2018-01-05 | 2018-01-09 | 7,949 | — | $0 | 41,310 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2018-01-05 | 2018-01-09 | 7,949 | $7.95 | $63.2K | 205,746 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2018-01-05 | 2018-01-09 | 7,949 | $0.45 | $3.6K | 213,695 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2018-01-02 | 2018-01-03 | 13,068 | — | $0 | 147,322 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2018-01-02 | 2018-01-03 | 6,932 | — | $0 | 92,813 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2018-01-02 | 2018-01-03 | 6,932 | $1.45 | $10.1K | 210,745 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | S Sale | 2018-01-02 | 2018-01-03 | 20,000 | $7.61 | $152.2K | 190,745 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2018-01-02 | 2018-01-03 | 13,068 | $0.82 | $10.7K | 203,813 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-12-29 | 2018-01-03 | 42,000 | — | $0 | 160,390 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise deriv | 2017-12-29 | 2018-01-03 | 52,000 | — | $0 | 173,998 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-12-29 | 2018-01-03 | 42,000 | $0.82 | $34.4K | 190,745 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise | 2017-12-29 | 2018-01-03 | 52,000 | $1.45 | $75.4K | 124,603 | SEC↗ |
| Templeman Blaine | Executive VP, General Counse | S Sale | 2017-12-18 | 2017-12-20 | 2,884 | $8.25 | $23.8K | 69,937 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise deriv | 2017-12-15 | 2017-12-15 | 64,108 | — | $0 | 225,998 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise | 2017-12-15 | 2017-12-15 | 64,108 | $1.45 | $93.0K | 137,826 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | S Sale | 2017-12-15 | 2017-12-15 | 65,223 | $8.11 | $529.0K | 72,603 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | G Gift | 2017-12-15 | 2017-12-15 | 61,725 | — | $0 | 8,932 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | G Gift | 2017-12-15 | 2017-12-15 | 12,375 | — | $0 | 205,746 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | A Award | 2017-12-11 | 2017-12-13 | 11,650 | — | $0 | 73,988 | SEC↗ |
| Templeman Blaine | Executive VP, General Counse | A Award | 2017-12-11 | 2017-12-13 | 13,987 | — | $0 | 72,821 | SEC↗ |
| Sacks Natalie | Chief Medical Officer | A Award | 2017-12-11 | 2017-12-13 | 16,312 | — | $0 | 94,052 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | A Award | 2017-12-11 | 2017-12-13 | 44,200 | — | $0 | 218,121 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | A Award | 2017-12-11 | 2017-12-15 | 4,650 | — | $0 | 207,231 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | A Award | 2017-12-11 | 2017-12-15 | 16,312 | — | $0 | 223,543 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2017-12-01 | 2017-12-04 | 40,000 | — | $0 | 49,259 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-12-01 | 2017-12-04 | 6,931 | — | $0 | 99,745 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-12-01 | 2017-12-04 | 13,069 | — | $0 | 202,390 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | M Exercise deriv | 2017-12-01 | 2017-12-04 | 6,600 | — | $0 | 50,709 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise deriv | 2017-12-01 | 2017-12-04 | 3,956 | — | $0 | 42,000 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise deriv | 2017-12-01 | 2017-12-04 | 6,044 | — | $0 | 55,014 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2017-12-01 | 2017-12-04 | 40,000 | $9.38 | $375.2K | 173,921 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2017-12-01 | 2017-12-04 | 40,000 | $0.45 | $18.0K | 213,921 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-12-01 | 2017-12-04 | 13,069 | $0.82 | $10.7K | 168,745 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-12-01 | 2017-12-04 | 6,931 | $1.45 | $10.0K | 155,676 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | S Sale | 2017-12-01 | 2017-12-04 | 20,000 | $9.34 | $186.8K | 148,745 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | M Exercise | 2017-12-01 | 2017-12-04 | 6,600 | $0.82 | $5.4K | 68,938 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | S Sale | 2017-12-01 | 2017-12-04 | 6,600 | $9.46 | $62.4K | 62,338 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise | 2017-12-01 | 2017-12-04 | 6,044 | $0.52 | $3.1K | 83,718 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | S Sale | 2017-12-01 | 2017-12-04 | 10,000 | $9.40 | $94.0K | 73,718 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise | 2017-12-01 | 2017-12-04 | 3,956 | $0.52 | $2.1K | 77,674 | SEC↗ |
| Templeman Blaine | Executive VP, General Counse | S Sale | 2017-11-17 | 2017-11-17 | 243 | $8.85 | $2.2K | 58,834 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | M Exercise deriv | 2017-11-15 | 2017-11-17 | 6,600 | — | $0 | 57,309 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | M Exercise | 2017-11-15 | 2017-11-17 | 6,600 | $0.82 | $5.4K | 68,938 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | S Sale | 2017-11-15 | 2017-11-17 | 6,600 | $8.95 | $59.1K | 62,338 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise deriv | 2017-11-13 | 2017-11-14 | 4,062 | — | $0 | 45,956 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2017-11-13 | 2017-11-14 | 3,400 | — | $0 | 89,259 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | S Sale | 2017-11-13 | 2017-11-14 | 4,062 | $8.00 | $32.5K | 73,718 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise | 2017-11-13 | 2017-11-14 | 4,062 | $0.52 | $2.1K | 77,780 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2017-11-13 | 2017-11-14 | 3,400 | $8.00 | $27.2K | 173,921 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2017-11-13 | 2017-11-14 | 3,400 | $0.45 | $1.5K | 177,321 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise deriv | 2017-11-10 | 2017-11-14 | 1,815 | — | $0 | 50,018 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2017-11-10 | 2017-11-14 | 16,400 | — | $0 | 92,659 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | S Sale | 2017-11-10 | 2017-11-14 | 1,815 | $8.01 | $14.5K | 73,718 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise | 2017-11-10 | 2017-11-14 | 1,815 | $0.52 | $944 | 75,533 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2017-11-10 | 2017-11-14 | 16,400 | $0.45 | $7.4K | 190,321 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2017-11-10 | 2017-11-14 | 16,400 | $7.96 | $130.5K | 173,921 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2017-11-07 | 2017-11-08 | 3,800 | — | $0 | 109,059 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2017-11-07 | 2017-11-08 | 3,800 | $0.45 | $1.7K | 177,721 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2017-11-07 | 2017-11-08 | 3,800 | $7.95 | $30.2K | 173,921 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2017-11-06 | 2017-11-08 | 16,400 | — | $0 | 112,859 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise deriv | 2017-11-06 | 2017-11-08 | 4,123 | — | $0 | 51,833 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-11-06 | 2017-11-08 | 13,068 | — | $0 | 215,459 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-11-06 | 2017-11-08 | 6,932 | — | $0 | 106,676 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2017-11-06 | 2017-11-08 | 16,400 | $0.45 | $7.4K | 190,321 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2017-11-06 | 2017-11-08 | 16,400 | $7.98 | $130.9K | 173,921 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | S Sale | 2017-11-06 | 2017-11-08 | 4,123 | $8.04 | $33.1K | 73,718 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise | 2017-11-06 | 2017-11-08 | 4,123 | $0.52 | $2.1K | 77,841 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-11-06 | 2017-11-08 | 13,068 | $0.82 | $10.7K | 168,745 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-11-06 | 2017-11-08 | 6,932 | $1.45 | $10.1K | 155,677 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | S Sale | 2017-11-06 | 2017-11-08 | 20,000 | $7.97 | $159.4K | 148,745 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | M Exercise deriv | 2017-10-02 | 2017-10-04 | 6,600 | — | $0 | 63,909 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2017-10-02 | 2017-10-04 | 40,000 | — | $0 | 129,259 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-10-02 | 2017-10-04 | 17,060 | — | $0 | 113,608 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-10-02 | 2017-10-04 | 2,940 | — | $0 | 228,527 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise deriv | 2017-10-02 | 2017-10-04 | 10,000 | — | $0 | 55,956 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | S Sale | 2017-10-02 | 2017-10-04 | 6,600 | $10.61 | $70.0K | 62,338 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | M Exercise | 2017-10-02 | 2017-10-04 | 6,600 | $0.82 | $5.4K | 68,938 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2017-10-02 | 2017-10-04 | 40,000 | $10.78 | $431.2K | 173,921 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2017-10-02 | 2017-10-04 | 40,000 | $0.45 | $18.0K | 213,921 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | S Sale | 2017-10-02 | 2017-10-04 | 20,000 | $10.75 | $215.0K | 148,745 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-10-02 | 2017-10-04 | 17,060 | $1.45 | $24.7K | 165,805 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-10-02 | 2017-10-04 | 2,940 | $0.82 | $2.4K | 168,745 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | S Sale | 2017-10-02 | 2017-10-04 | 10,000 | $10.59 | $105.9K | 73,718 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise | 2017-10-02 | 2017-10-04 | 10,000 | $0.52 | $5.2K | 83,718 | SEC↗ |
| Templeman Blaine | Executive VP, General Counse | S Sale | 2017-09-18 | 2017-09-20 | 2,884 | $11.20 | $32.3K | 58,834 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2017-09-13 | 2017-12-15 | 4,922 | $10.99 | $54.1K | 202,581 | SEC↗ |
| Templeman Blaine | Executive VP, General Counse | S Sale | 2017-09-13 | 2017-09-14 | 3,557 | $10.99 | $39.1K | 61,718 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | S Sale | 2017-09-13 | 2017-09-14 | 4,922 | $10.99 | $54.1K | 207,231 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | S Sale | 2017-09-13 | 2017-09-14 | 3,557 | $10.99 | $39.1K | 62,338 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | S Sale | 2017-09-13 | 2017-09-14 | 3,557 | $10.99 | $39.1K | 73,718 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | S Sale | 2017-09-13 | 2017-09-14 | 4,859 | $10.99 | $53.4K | 148,745 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2017-09-13 | 2017-09-14 | 12,204 | $10.99 | $134.1K | 173,921 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | A Award | 2017-09-12 | 2017-12-15 | 27,975 | — | $0 | 207,503 | SEC↗ |
| Templeman Blaine | Executive VP, General Counse | A Award | 2017-09-12 | 2017-09-14 | 27,975 | — | $0 | 65,275 | SEC↗ |
| van Elsas Andrea | Chief Scientific Officer | A Award | 2017-09-12 | 2017-09-14 | 32,625 | — | $0 | 212,153 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | A Award | 2017-09-12 | 2017-09-14 | 23,300 | — | $0 | 65,895 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | A Award | 2017-09-12 | 2017-09-14 | 27,975 | — | $0 | 77,275 | SEC↗ |
| Sacks Natalie | Chief Medical Officer | A Award | 2017-09-12 | 2017-09-14 | 32,625 | — | $0 | 77,740 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | A Award | 2017-09-12 | 2017-09-14 | 32,625 | — | $0 | 153,604 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | A Award | 2017-09-12 | 2017-09-14 | 82,100 | — | $0 | 186,125 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise deriv | 2017-09-01 | 2017-09-06 | 10,000 | — | $0 | 144,291 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2017-09-01 | 2017-09-06 | 40,000 | — | $0 | 169,259 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | M Exercise deriv | 2017-09-01 | 2017-09-06 | 6,600 | — | $0 | 70,509 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-09-01 | 2017-09-06 | 9,334 | — | $0 | 201,883 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-09-01 | 2017-09-06 | 10,666 | — | $0 | 130,668 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | S Sale | 2017-09-01 | 2017-09-06 | 10,000 | $11.69 | $116.9K | 49,300 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise | 2017-09-01 | 2017-09-06 | 10,000 | $0.52 | $5.2K | 59,300 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2017-09-01 | 2017-09-06 | 40,000 | $0.45 | $18.0K | 144,025 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2017-09-01 | 2017-09-06 | 40,000 | $11.71 | $468.4K | 104,025 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | S Sale | 2017-09-01 | 2017-09-06 | 6,600 | $11.70 | $77.2K | 42,595 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | M Exercise | 2017-09-01 | 2017-09-06 | 6,600 | $0.82 | $5.4K | 49,195 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-09-01 | 2017-09-06 | 9,334 | $1.00 | $9.3K | 140,979 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-09-01 | 2017-09-06 | 10,666 | $1.45 | $15.5K | 131,645 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | S Sale | 2017-09-01 | 2017-09-06 | 20,000 | $11.70 | $234.0K | 120,979 | SEC↗ |
| Sacks Natalie | Chief Medical Officer | S Sale | 2017-09-01 | 2017-09-06 | 4,885 | $11.71 | $57.2K | 45,115 | SEC↗ |
| Dubensky Thomas W. | Chief Scientific Officer | M Exercise deriv | 2017-08-11 | 2017-08-11 | 9,088 | — | $0 | 126,328 | SEC↗ |
| Dubensky Thomas W. | Chief Scientific Officer | S Sale | 2017-08-11 | 2017-08-11 | 9,088 | $11.17 | $101.5K | 39,900 | SEC↗ |
| Dubensky Thomas W. | Chief Scientific Officer | M Exercise | 2017-08-11 | 2017-08-11 | 9,088 | $1.00 | $9.1K | 48,988 | SEC↗ |
| Dubensky Thomas W. | Chief Scientific Officer | M Exercise deriv | 2017-08-10 | 2017-08-11 | 40,912 | — | $0 | 135,416 | SEC↗ |
| Dubensky Thomas W. | Chief Scientific Officer | M Exercise | 2017-08-10 | 2017-08-11 | 40,912 | $1.00 | $40.9K | 80,812 | SEC↗ |
| Dubensky Thomas W. | Chief Scientific Officer | S Sale | 2017-08-10 | 2017-08-11 | 40,912 | $11.43 | $467.6K | 39,900 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-08-08 | 2017-08-09 | 5,711 | — | $0 | 211,217 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-08-08 | 2017-08-09 | 8,478 | — | $0 | 141,334 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | S Sale | 2017-08-08 | 2017-08-09 | 14,189 | $12.16 | $172.5K | 120,979 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-08-08 | 2017-08-09 | 5,711 | $1.00 | $5.7K | 135,168 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-08-08 | 2017-08-09 | 8,478 | $1.45 | $12.3K | 129,457 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | M Exercise deriv | 2017-08-07 | 2017-08-09 | 6,600 | — | $0 | 77,109 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise deriv | 2017-08-07 | 2017-08-09 | 10,000 | — | $0 | 154,291 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-08-07 | 2017-08-09 | 12,900 | — | $0 | 149,812 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise deriv | 2017-08-07 | 2017-08-09 | 12,911 | — | $0 | 216,928 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise deriv | 2017-08-07 | 2017-08-09 | 40,000 | — | $0 | 209,259 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | S Sale | 2017-08-07 | 2017-08-09 | 6,600 | $12.17 | $80.3K | 42,595 | SEC↗ |
| Lew Jennifer | Sr. Vice President of Financ | M Exercise | 2017-08-07 | 2017-08-09 | 6,600 | $0.82 | $5.4K | 49,195 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | S Sale | 2017-08-07 | 2017-08-09 | 10,000 | $12.18 | $121.8K | 49,300 | SEC↗ |
| Brockstedt Dirk G. | EVP of Research and Dev. | M Exercise | 2017-08-07 | 2017-08-09 | 10,000 | $0.52 | $5.2K | 59,300 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | S Sale | 2017-08-07 | 2017-08-09 | 25,811 | $12.17 | $314.1K | 120,979 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-08-07 | 2017-08-09 | 12,911 | $1.00 | $12.9K | 146,790 | SEC↗ |
| SCHAFER GREGORY W | Chief Operating Officer | M Exercise | 2017-08-07 | 2017-08-09 | 12,900 | $1.45 | $18.7K | 133,879 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | S Sale | 2017-08-07 | 2017-08-09 | 40,000 | $12.19 | $487.6K | 104,025 | SEC↗ |
| ISAACS STEPHEN T | President and CEO | M Exercise | 2017-08-07 | 2017-08-09 | 40,000 | $0.45 | $18.0K | 144,025 | SEC↗ |
| Dubensky Thomas W. | Chief Scientific Officer | M Exercise deriv | 2017-07-06 | 2017-07-06 | 4,512 | — | $0 | 13,571 | SEC↗ |
| Dubensky Thomas W. | Chief Scientific Officer | S Sale | 2017-07-06 | 2017-07-06 | 4,512 | $11.23 | $50.7K | 39,900 | SEC↗ |