Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$0
Insiders on file
39
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Fairmount Healthcare Co-Invest L.P. | Director, 10% Owner | 2 | $0 | $0 | 2023-11-24 |
| Turtle Cameron | Chief Executive Officer | 3 | $0 | $0 | 2023-11-24 |
| Stelzer Laurie | Director | 1 | $0 | $0 | 2023-11-22 |
| Albers Jeffrey W. | Director | 1 | $0 | $0 | 2023-11-22 |
| Burrows Scott L | Chief Financial Officer | 1 | $0 | $0 | 2023-09-01 |
| King-Jones Heidy | See Remarks | 1 | $0 | $0 | 2023-09-01 |
| Alspaugh Jonathan | President and CFO | 10 | $604.7K | $0 | 2023-06-22 |
| Smith Hunter C | Director | 3 | $0 | $0 | 2023-06-22 |
| Lawton Alison Frances | Director | 4 | $0 | $0 | 2023-06-22 |
| Cox Russell J. | Director | 9 | $70.0K | $0 | 2023-06-22 |
| Magovcevic-Liebisch Ivana | Director | 6 | $0 | $0 | 2023-06-22 |
| Neuman Linda L | Chief Medical Officer | 2 | $0 | $0 | 2023-02-23 |
| Kastenmayer James Paul | Interim CEO & General Counsel | 2 | $0 | $0 | 2023-02-23 |
| Hanley Jr. Michael Conick | Chief Commercial Officer | 7 | $20.0K | $0 | 2023-02-23 |
| Goldberg Jeff Marc | President and CEO | 1 | $0 | $0 | 2022-11-29 |
| Souza Marcio | Director | 3 | $50.4K | $0 | 2022-08-25 |
| Sloan Leslie | Chief Operating Officer | 5 | $0 | $0 | 2022-08-23 |
| Shanafelt Armen | Director, 10% Owner | 11 | $549.9K | $0 | 2022-06-07 |
| Mahatme Sandesh | Director | 7 | $0 | $0 | 2022-06-07 |
| LAWLIS V BRYAN | Director | 5 | $0 | $0 | 2022-06-07 |
| Quinn Anthony G. | interim Chief Medical Officer | 59 | $2.20M | $0 | 2022-03-16 |
| Weber Steven | VP, Controller&Princ Acctg Off | 2 | $0 | $0 | 2022-02-17 |
| BAKER FELIX | Director | 1 | $0 | $0 | 2021-06-08 |
| BAKER BROS. ADVISORS LP | Director | 1 | $0 | $0 | 2021-02-23 |
| Bruhn Suzanne Louise | Director | 4 | $0 | $0 | 2020-06-08 |
| Rao Madduri Ravin | Chief Medical Officer | 2 | $0 | $0 | 2020-02-14 |
| York Charles N II | Chief Financial Officer and VP | 17 | $116.3K | $0 | 2020-02-14 |
| Wooldridge James | Chief Medical Officer | 4 | $0 | $0 | 2019-02-28 |
| Schuchart Aaron | Chief Business Officer | 8 | $0 | $57.0K | 2019-02-28 |
| GEORGIOU GEORGE | Director | 7 | $0 | $0 | 2018-08-13 |
| Novartis Bioventures Ltd | 10% Owner | 3 | $0 | $944.8K | 2018-05-11 |
| NOVARTIS AG | 10% Owner | 6 | $3.00M | $423.6K | 2018-05-08 |
| Rowlinson Scott W | VP, Research | 5 | $0 | $0 | 2017-08-22 |
| TYLER JOSEPH E | VP, Manufacturing | 6 | $0 | $0 | 2017-08-22 |
| Hebel Henry | VP, Product Development | 2 | $0 | $0 | 2017-03-20 |
| Lowe David George | CEO and President | 5 | $0 | $0 | 2017-03-20 |
| ORBIMED ADVISORS LLC | 10% Owner | 3 | $563.9K | $0 | 2017-02-21 |
| Rojas-Caro Sandra | Chief Medical Officer | 1 | $0 | $0 | 2016-05-17 |
| LILLY ELI & CO | 10% Owner | 4 | $5.00M | $0 | 2016-04-12 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Turtle Cameron | Chief Executive Officer | C Conversion deriv | 2023-11-24 | 2023-11-27 | 18,086 | — | $0 | 0 | SEC↗ |
| Fairmount Healthcare Co-Invest | Director, 10% Owner | C Conversion deriv | 2023-11-24 | 2023-11-28 | 85,887 | — | $0 | 0 | SEC↗ |
| Turtle Cameron | Chief Executive Officer | C Conversion | 2023-11-24 | 2023-11-27 | 723,440 | — | $0 | 746,507 | SEC↗ |
| Fairmount Healthcare Co-Invest | Director, 10% Owner | C Conversion | 2023-11-24 | 2023-11-28 | 3,435,480 | — | $0 | 3,435,480 | SEC↗ |
| Turtle Cameron | Chief Executive Officer | A Award deriv | 2023-11-22 | 2023-11-27 | 374,000 | — | $0 | 374,000 | SEC↗ |
| Stelzer Laurie | Director | A Award deriv | 2023-11-22 | 2023-11-27 | 50,000 | — | $0 | 50,000 | SEC↗ |
| Albers Jeffrey W. | Director | A Award deriv | 2023-11-22 | 2023-11-27 | 50,000 | — | $0 | 50,000 | SEC↗ |
| Burrows Scott L | Chief Financial Officer | A Award deriv | 2023-09-01 | 2023-09-05 | 10,121,441 | — | $0 | 10,121,441 | SEC↗ |
| King-Jones Heidy | See Remarks | A Award deriv | 2023-09-01 | 2023-09-05 | 13,495,255 | — | $0 | 13,495,255 | SEC↗ |
| Lawton Alison Frances | Director | A Award deriv | 2023-06-22 | 2023-06-30 | 1,950,000 | — | $0 | 1,950,000 | SEC↗ |
| Smith Hunter C | Director | A Award deriv | 2023-06-22 | 2023-06-30 | 1,950,000 | — | $0 | 1,950,000 | SEC↗ |
| Magovcevic-Liebisch Ivana | Director | A Award deriv | 2023-06-22 | 2023-06-30 | 1,950,000 | — | $0 | 1,950,000 | SEC↗ |
| Cox Russell J. | Director | A Award deriv | 2023-06-22 | 2023-06-30 | 1,950,000 | — | $0 | 1,950,000 | SEC↗ |
| Alspaugh Jonathan | President and CFO | A Award deriv | 2023-06-22 | 2023-06-30 | 19,787,969 | — | $0 | 19,787,969 | SEC↗ |
| Alspaugh Jonathan | Chief Financial Officer | A Award deriv | 2023-02-23 | 2023-02-24 | 640,000 | — | $0 | 640,000 | SEC↗ |
| Hanley Jr. Michael Conick | Chief Business Officer | A Award deriv | 2023-02-23 | 2023-02-24 | 500,000 | — | $0 | 500,000 | SEC↗ |
| Kastenmayer James Paul | General Counsel | A Award deriv | 2023-02-23 | 2023-02-24 | 500,000 | — | $0 | 500,000 | SEC↗ |
| Neuman Linda L | Chief Medical Officer | A Award deriv | 2023-02-23 | 2023-02-24 | 550,000 | — | $0 | 550,000 | SEC↗ |
| Goldberg Jeff Marc | President and CEO | A Award deriv | 2022-11-29 | 2022-12-01 | 1,884,838 | — | $0 | 1,884,838 | SEC↗ |
| Neuman Linda L | Chief Medical Officer | A Award deriv | 2022-11-14 | 2023-01-27 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Souza Marcio | Director | P Buy | 2022-08-25 | 2022-08-25 | 90,000 | $0.56 | $50.4K | 90,000 | SEC↗ |
| Alspaugh Jonathan | Chief Financial Officer | A Award deriv | 2022-08-23 | 2022-08-25 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Hanley Jr. Michael Conick | Chief Business Officer | A Award deriv | 2022-08-23 | 2022-08-25 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Sloan Leslie | Chief Operating Officer | A Award deriv | 2022-08-23 | 2022-08-25 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Kastenmayer James Paul | Interim CEO & General Counse | A Award deriv | 2022-08-23 | 2022-08-25 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Hanley Jr. Michael Conick | Chief Commercial Officer | P Buy | 2022-06-08 | 2022-06-10 | 28,200 | $0.71 | $20.0K | 36,200 | SEC↗ |
| Cox Russell J. | Director | A Award deriv | 2022-06-07 | 2022-06-09 | 43,000 | — | $0 | 43,000 | SEC↗ |
| LAWLIS V BRYAN | Director | A Award deriv | 2022-06-07 | 2022-06-09 | 43,000 | — | $0 | 43,000 | SEC↗ |
| Magovcevic-Liebisch Ivana | Director | A Award deriv | 2022-06-07 | 2022-06-09 | 43,000 | — | $0 | 43,000 | SEC↗ |
| Mahatme Sandesh | Director | A Award deriv | 2022-06-07 | 2022-06-09 | 43,000 | — | $0 | 43,000 | SEC↗ |
| Smith Hunter C | Director | A Award deriv | 2022-06-07 | 2022-06-09 | 43,000 | — | $0 | 43,000 | SEC↗ |
| Souza Marcio | Director | A Award deriv | 2022-06-07 | 2022-06-09 | 43,000 | — | $0 | 43,000 | SEC↗ |
| Shanafelt Armen | Director | A Award deriv | 2022-06-07 | 2022-06-09 | 43,000 | — | $0 | 43,000 | SEC↗ |
| Lawton Alison Frances | Director | A Award deriv | 2022-06-07 | 2022-06-10 | 43,000 | — | $0 | 43,000 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2022-03-16 | 2022-03-18 | 80,079 | $2.34 | $187.4K | 550,540 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2022-03-15 | 2022-03-15 | 42,417 | $1.86 | $78.9K | 473,461 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2022-03-14 | 2022-03-15 | 67,472 | $1.93 | $130.2K | 431,044 | SEC↗ |
| Alspaugh Jonathan | Chief Financial Officer | P Buy | 2022-03-11 | 2022-03-15 | 75,000 | $2.08 | $156.0K | 165,372 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2022-03-11 | 2022-03-15 | 34,777 | $2.06 | $71.6K | 363,572 | SEC↗ |
| Alspaugh Jonathan | Chief Financial Officer | A Award deriv | 2022-02-17 | 2022-02-22 | 170,000 | — | $0 | 170,000 | SEC↗ |
| Hanley Jr. Michael Conick | Chief Commercial Officer | A Award deriv | 2022-02-17 | 2022-02-22 | 160,000 | — | $0 | 160,000 | SEC↗ |
| Sloan Leslie | Chief Operating Officer | A Award deriv | 2022-02-17 | 2022-02-22 | 180,000 | — | $0 | 180,000 | SEC↗ |
| Weber Steven | VP, Controller&Princ Acctg O | A Award deriv | 2022-02-17 | 2022-02-22 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Quinn Anthony G. | President & CEO | A Award deriv | 2022-02-17 | 2022-02-22 | 350,000 | — | $0 | 350,000 | SEC↗ |
| Shanafelt Armen | Director | P Buy | 2021-12-13 | 2021-12-13 | 14,685 | $3.65 | $53.6K | 150,000 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2021-12-10 | 2021-12-13 | 10,526 | $3.75 | $39.5K | 328,795 | SEC↗ |
| Shanafelt Armen | Director | P Buy | 2021-12-10 | 2021-12-13 | 13,516 | $3.65 | $49.3K | 135,315 | SEC↗ |
| Alspaugh Jonathan | Chief Financial Officer | P Buy | 2021-12-09 | 2021-12-13 | 50,000 | $3.72 | $186.0K | 90,372 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2021-12-09 | 2021-12-13 | 43,108 | $3.70 | $159.5K | 318,269 | SEC↗ |
| Shanafelt Armen | Director | P Buy | 2021-12-09 | 2021-12-13 | 121,799 | $3.67 | $447.0K | 121,799 | SEC↗ |
| Smith Hunter C | Director | A Award deriv | 2021-11-12 | 2021-11-16 | 60,000 | — | $0 | 60,000 | SEC↗ |
| Alspaugh Jonathan | Chief Financial Officer | P Buy | 2021-08-18 | 2021-08-18 | 7,200 | $6.72 | $48.4K | 40,372 | SEC↗ |
| Alspaugh Jonathan | Chief Financial Officer | P Buy | 2021-08-17 | 2021-08-18 | 23,392 | $6.50 | $152.0K | 33,172 | SEC↗ |
| Alspaugh Jonathan | Chief Financial Officer | P Buy | 2021-08-16 | 2021-08-18 | 9,780 | $6.37 | $62.3K | 9,780 | SEC↗ |
| Alspaugh Jonathan | Chief Financial Officer | A Award deriv | 2021-07-06 | 2021-07-08 | 160,000 | — | $0 | 160,000 | SEC↗ |
| Souza Marcio | Director | A Award deriv | 2021-06-18 | 2021-06-22 | 60,000 | — | $0 | 60,000 | SEC↗ |
| Cox Russell J. | Director | A Award deriv | 2021-06-08 | 2021-06-09 | 40,000 | — | $0 | 40,000 | SEC↗ |
| LAWLIS V BRYAN | Director | A Award deriv | 2021-06-08 | 2021-06-09 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Lawton Alison Frances | Director | A Award deriv | 2021-06-08 | 2021-06-09 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Magovcevic-Liebisch Ivana | Director | A Award deriv | 2021-06-08 | 2021-06-09 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Mahatme Sandesh | Director | A Award deriv | 2021-06-08 | 2021-06-09 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Shanafelt Armen | Director | A Award deriv | 2021-06-08 | 2021-06-09 | 40,000 | — | $0 | 40,000 | SEC↗ |
| BAKER FELIX | Director | A Award deriv | 2021-06-08 | 2021-06-10 | 40,000 | — | $0 | 40,000 | SEC↗ |
| BAKER BROS. ADVISORS LP | Director | A Award deriv | 2021-02-23 | 2021-02-25 | 47,200 | — | $0 | 47,200 | SEC↗ |
| Hanley Jr. Michael Conick | Chief Commercial Officer | A Award deriv | 2021-02-17 | 2021-02-19 | 135,000 | — | $0 | 135,000 | SEC↗ |
| Quinn Anthony G. | President & CEO | A Award deriv | 2021-02-17 | 2021-02-19 | 330,000 | — | $0 | 330,000 | SEC↗ |
| Sloan Leslie | Chief Operating Officer | A Award deriv | 2021-02-17 | 2021-02-19 | 160,000 | — | $0 | 160,000 | SEC↗ |
| Weber Steven | VP, Controller&Princ Acctg O | A Award deriv | 2021-02-17 | 2021-02-19 | 50,000 | — | $0 | 50,000 | SEC↗ |
| Lawton Alison Frances | Director | A Award deriv | 2020-12-15 | 2020-12-17 | 47,200 | — | $0 | 47,200 | SEC↗ |
| Bruhn Suzanne Louise | Director | A Award deriv | 2020-06-08 | 2020-06-10 | 28,100 | — | $0 | 28,100 | SEC↗ |
| Cox Russell J. | Director | A Award deriv | 2020-06-08 | 2020-06-10 | 28,100 | — | $0 | 28,100 | SEC↗ |
| LAWLIS V BRYAN | Director | A Award deriv | 2020-06-08 | 2020-06-10 | 28,100 | — | $0 | 28,100 | SEC↗ |
| Magovcevic Ivana | Director | A Award deriv | 2020-06-08 | 2020-06-10 | 28,100 | — | $0 | 28,100 | SEC↗ |
| Mahatme Sandesh | Director | A Award deriv | 2020-06-08 | 2020-06-10 | 28,100 | — | $0 | 28,100 | SEC↗ |
| Shanafelt Armen | Director | A Award deriv | 2020-06-08 | 2020-06-10 | 28,100 | — | $0 | 28,100 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2020-04-30 | 2020-05-04 | 165,000 | $4.75 | $783.8K | 538,469 | SEC↗ |
| Hanley Jr. Michael Conick | Chief Commercial Officer | A Award deriv | 2020-02-14 | 2020-02-19 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Quinn Anthony G. | President & CEO | A Award deriv | 2020-02-14 | 2020-02-19 | 301,000 | — | $0 | 301,000 | SEC↗ |
| Rao Madduri Ravin | Chief Medical Officer | A Award deriv | 2020-02-14 | 2020-02-19 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Sloan Leslie | Chief Operating Officer | A Award deriv | 2020-02-14 | 2020-02-19 | 100,000 | — | $0 | 100,000 | SEC↗ |
| York Charles N II | Chief Financial Officer and | A Award deriv | 2020-02-14 | 2020-02-19 | 126,000 | — | $0 | 126,000 | SEC↗ |
| Rao Madduri Ravin | Chief Medical Officer | A Award deriv | 2019-11-01 | 2019-11-04 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Hanley Jr. Michael Conick | Chief Commercial Officer | A Award deriv | 2019-10-21 | 2019-10-23 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise deriv | 2019-10-04 | 2019-10-07 | 17,603 | — | $0 | 119,914 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise deriv | 2019-10-04 | 2019-10-07 | 662 | — | $0 | 0 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise | 2019-10-04 | 2019-10-07 | 662 | $5.46 | $3.6K | 354,305 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise | 2019-10-04 | 2019-10-07 | 17,603 | $6.31 | $111.1K | 371,908 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2019-06-14 | 2019-06-14 | 5,282 | $6.23 | $32.9K | 353,643 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2019-06-13 | 2019-06-14 | 14,406 | $6.17 | $88.9K | 348,361 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2019-06-12 | 2019-06-14 | 12,217 | $6.11 | $74.6K | 333,955 | SEC↗ |
| Bruhn Suzanne Louise | Director | A Award deriv | 2019-06-07 | 2019-06-07 | 12,400 | — | $0 | 12,400 | SEC↗ |
| Cox Russell J. | Director | A Award deriv | 2019-06-07 | 2019-06-07 | 12,400 | — | $0 | 12,400 | SEC↗ |
| Magovcevic Ivana | Director | A Award deriv | 2019-06-07 | 2019-06-07 | 12,400 | — | $0 | 12,400 | SEC↗ |
| Mahatme Sandesh | Director | A Award deriv | 2019-06-07 | 2019-06-07 | 12,400 | — | $0 | 12,400 | SEC↗ |
| Shanafelt Armen | Director | A Award deriv | 2019-06-07 | 2019-06-07 | 12,400 | — | $0 | 12,400 | SEC↗ |
| LAWLIS V BRYAN | Director | A Award deriv | 2019-06-07 | 2019-06-07 | 12,400 | — | $0 | 12,400 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2019-05-22 | 2019-05-22 | 3,809 | $6.86 | $26.1K | 321,738 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2019-05-21 | 2019-05-22 | 13,794 | $6.89 | $95.0K | 317,929 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2019-05-20 | 2019-05-22 | 8,989 | $6.56 | $59.0K | 304,135 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2019-05-17 | 2019-05-17 | 6,218 | $6.65 | $41.3K | 295,146 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2019-05-16 | 2019-05-17 | 5,520 | $6.83 | $37.7K | 288,928 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2019-05-15 | 2019-05-17 | 6,256 | $6.76 | $42.3K | 283,408 | SEC↗ |
| Sloan Leslie | Chief Operating Officer | A Award deriv | 2019-03-06 | 2019-03-08 | 36,000 | — | $0 | 36,000 | SEC↗ |
| Quinn Anthony G. | President & CEO | A Award deriv | 2019-02-28 | 2019-03-01 | 280,000 | — | $0 | 280,000 | SEC↗ |
| Schuchart Aaron | Chief Business Officer | A Award deriv | 2019-02-28 | 2019-03-01 | 60,000 | — | $0 | 60,000 | SEC↗ |
| Wooldridge James | Chief Medical Officer | A Award deriv | 2019-02-28 | 2019-03-01 | 50,200 | — | $0 | 50,200 | SEC↗ |
| York Charles N II | Chief Financial Officer and | A Award deriv | 2019-02-28 | 2019-03-01 | 87,600 | — | $0 | 87,600 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2019-02-15 | 2019-05-17 | 719 | $7.10 | $5.1K | 277,152 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise deriv | 2019-02-06 | 2019-02-08 | 1,323 | — | $0 | 662 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise deriv | 2019-02-06 | 2019-02-08 | 7,433 | — | $0 | 137,517 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise | 2019-02-06 | 2019-02-08 | 7,433 | $6.31 | $46.9K | 276,433 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise | 2019-02-06 | 2019-02-08 | 1,323 | $5.46 | $7.2K | 269,000 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise deriv | 2018-12-07 | 2018-12-10 | 3,306 | — | $0 | 1,985 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise deriv | 2018-12-07 | 2018-12-10 | 18,584 | — | $0 | 144,950 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise deriv | 2018-12-07 | 2018-12-10 | 150,000 | — | $0 | 0 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise | 2018-12-07 | 2018-12-10 | 150,000 | $4.11 | $616.5K | 245,787 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise | 2018-12-07 | 2018-12-10 | 3,306 | $5.46 | $18.1K | 249,093 | SEC↗ |
| Quinn Anthony G. | President & CEO | M Exercise | 2018-12-07 | 2018-12-10 | 18,584 | $6.31 | $117.3K | 267,677 | SEC↗ |
| Schuchart Aaron | Chief Business Officer | S Sale | 2018-09-27 | 2018-09-28 | 5,900 | $9.50 | $56.0K | 2,500 | SEC↗ |
| Schuchart Aaron | Chief Business Officer | S Sale | 2018-09-27 | 2018-09-28 | 100 | $9.55 | $955 | 8,400 | SEC↗ |
| Schuchart Aaron | Chief Business Officer | M Exercise deriv | 2018-08-17 | 2018-08-21 | 8,500 | — | $0 | 91,500 | SEC↗ |
| Schuchart Aaron | Chief Business Officer | M Exercise | 2018-08-17 | 2018-08-21 | 8,500 | $3.50 | $29.8K | 8,500 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2018-08-15 | 2018-12-10 | 994 | $9.13 | $9.1K | 95,787 | SEC↗ |
| GEORGIOU GEORGE | Director | M Exercise deriv | 2018-08-13 | 2018-08-15 | 17,333 | — | $0 | 6,667 | SEC↗ |
| GEORGIOU GEORGE | Director | M Exercise deriv | 2018-08-13 | 2018-08-15 | 20,000 | — | $0 | 10,000 | SEC↗ |
| GEORGIOU GEORGE | Director | M Exercise | 2018-08-13 | 2018-08-15 | 20,000 | $4.73 | $94.6K | 175,861 | SEC↗ |
| GEORGIOU GEORGE | Director | M Exercise | 2018-08-13 | 2018-08-15 | 17,333 | $7.28 | $126.2K | 155,861 | SEC↗ |
| Quinn Anthony G. | President & CEO | A Award deriv | 2018-07-18 | 2018-07-20 | 50,000 | — | $0 | 50,000 | SEC↗ |
| Quinn Anthony G. | President & CEO | A Award deriv | 2018-07-18 | 2018-07-20 | 300,000 | — | $0 | 300,000 | SEC↗ |
| Quinn Anthony G. | President & CEO | A Award deriv | 2018-07-18 | 2018-07-20 | 75,000 | — | $0 | 75,000 | SEC↗ |
| Quinn Anthony G. | President & CEO | A Award deriv | 2018-07-18 | 2018-07-20 | 75,000 | — | $0 | 75,000 | SEC↗ |
| LAWLIS V BRYAN | Director | A Award deriv | 2018-07-13 | 2018-07-17 | 36,800 | — | $0 | 36,800 | SEC↗ |
| Quinn Anthony G. | Interim CEO | M Exercise deriv | 2018-07-12 | 2018-07-16 | 24,000 | — | $0 | 0 | SEC↗ |
| Quinn Anthony G. | Interim CEO | M Exercise deriv | 2018-07-12 | 2018-07-16 | 14,866 | — | $0 | 163,534 | SEC↗ |
| Quinn Anthony G. | Interim CEO | M Exercise | 2018-07-12 | 2018-07-16 | 24,000 | $7.04 | $169.0K | 77,927 | SEC↗ |
| Quinn Anthony G. | Interim CEO | M Exercise | 2018-07-12 | 2018-07-16 | 14,866 | $6.31 | $93.8K | 92,793 | SEC↗ |
| Quinn Anthony G. | Interim CEO | M Exercise deriv | 2018-07-11 | 2018-07-13 | 3,307 | — | $0 | 5,291 | SEC↗ |
| Quinn Anthony G. | Interim CEO | M Exercise | 2018-07-11 | 2018-07-13 | 3,307 | $5.46 | $18.1K | 53,927 | SEC↗ |
| Bruhn Suzanne Louise | Director | A Award deriv | 2018-06-07 | 2018-06-08 | 18,400 | — | $0 | 18,400 | SEC↗ |
| Cox Russell J. | Director | A Award deriv | 2018-06-07 | 2018-06-08 | 18,400 | — | $0 | 18,400 | SEC↗ |
| GEORGIOU GEORGE | Director | A Award deriv | 2018-06-07 | 2018-06-08 | 18,400 | — | $0 | 18,400 | SEC↗ |
| Mahatme Sandesh | Director | A Award deriv | 2018-06-07 | 2018-06-08 | 18,400 | — | $0 | 18,400 | SEC↗ |
| Shanafelt Armen | Director, 10% Owner | A Award deriv | 2018-06-07 | 2018-06-08 | 18,400 | — | $0 | 18,400 | SEC↗ |
| Novartis Bioventures Ltd | 10% Owner | S Sale | 2018-05-11 | 2018-05-14 | 19,550 | $10.06 | $196.7K | 2,175,314 | SEC↗ |
| Novartis Bioventures Ltd | 10% Owner | S Sale | 2018-05-10 | 2018-05-11 | 22,725 | $10.13 | $230.2K | 2,194,864 | SEC↗ |
| Novartis Bioventures Ltd | 10% Owner | S Sale | 2018-05-09 | 2018-05-11 | 51,230 | $10.11 | $517.9K | 2,217,589 | SEC↗ |
| NOVARTIS AG | 10% Owner | S Sale | 2018-05-08 | 2018-05-09 | 26,557 | $10.03 | $266.4K | 2,268,819 | SEC↗ |
| NOVARTIS AG | 10% Owner | S Sale | 2018-05-07 | 2018-05-09 | 15,548 | $10.11 | $157.2K | 2,295,376 | SEC↗ |
| Magovcevic Ivana | Director | A Award deriv | 2018-03-22 | 2018-03-26 | 36,800 | — | $0 | 36,800 | SEC↗ |
| Schuchart Aaron | Chief Business Officer | A Award deriv | 2018-02-20 | 2018-02-22 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Quinn Anthony G. | Interim CEO | A Award deriv | 2018-02-20 | 2018-02-22 | 178,400 | — | $0 | 178,400 | SEC↗ |
| York Charles N II | Chief Financial Officer and | A Award deriv | 2018-02-20 | 2018-02-22 | 92,100 | — | $0 | 92,100 | SEC↗ |
| Wooldridge James | Chief Medical Officer | A Award deriv | 2018-02-20 | 2018-02-22 | 45,000 | — | $0 | 45,000 | SEC↗ |
| Quinn Anthony G. | President & CEO | P Buy | 2018-02-15 | 2018-12-10 | 2,000 | $6.02 | $12.0K | 94,793 | SEC↗ |
| Quinn Anthony G. | Interim CEO | M Exercise deriv | 2018-02-15 | 2018-02-20 | 15,211 | — | $0 | 8,598 | SEC↗ |
| Quinn Anthony G. | Interim CEO | M Exercise | 2018-02-15 | 2018-02-20 | 15,211 | $5.46 | $83.1K | 50,620 | SEC↗ |
| Quinn Anthony G. | Interim CEO | P Buy | 2017-12-08 | 2017-12-08 | 600 | $5.07 | $3.0K | 35,409 | SEC↗ |
| Quinn Anthony G. | Interim CEO | P Buy | 2017-12-07 | 2017-12-08 | 2,800 | $4.99 | $14.0K | 34,809 | SEC↗ |
| Quinn Anthony G. | Interim CEO | P Buy | 2017-12-06 | 2017-12-08 | 4,888 | $4.92 | $24.0K | 32,009 | SEC↗ |
| Quinn Anthony G. | Director | P Buy | 2017-12-05 | 2017-12-05 | 5,065 | $4.93 | $25.0K | 27,121 | SEC↗ |
| York Charles N II | Chief Financial Officer and | P Buy | 2017-12-05 | 2017-12-05 | 10,241 | $4.76 | $48.7K | 34,787 | SEC↗ |
| Quinn Anthony G. | Director | P Buy | 2017-12-04 | 2017-12-05 | 7,956 | $4.98 | $39.6K | 22,056 | SEC↗ |
| York Charles N II | Chief Financial Officer and | P Buy | 2017-12-04 | 2017-12-05 | 3,259 | $4.97 | $16.2K | 24,546 | SEC↗ |
| Cox Russell J. | Director | A Award deriv | 2017-12-01 | 2017-12-05 | 30,000 | — | $0 | 30,000 | SEC↗ |
| GEORGIOU GEORGE | Director | A Award deriv | 2017-12-01 | 2017-12-05 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Mahatme Sandesh | Director | A Award deriv | 2017-12-01 | 2017-12-05 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Shanafelt Armen | Director, 10% Owner | A Award deriv | 2017-12-01 | 2017-12-05 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Quinn Anthony G. | Director | P Buy | 2017-12-01 | 2017-12-05 | 4,100 | $4.53 | $18.6K | 14,100 | SEC↗ |
| York Charles N II | Chief Financial Officer and | P Buy | 2017-12-01 | 2017-12-05 | 6,500 | $4.59 | $29.8K | 21,287 | SEC↗ |
| Quinn Anthony G. | Interim CEO | A Award deriv | 2017-08-31 | 2017-09-01 | 150,000 | — | $0 | 150,000 | SEC↗ |
| Rowlinson Scott W | VP, Research | A Award deriv | 2017-08-22 | 2017-08-24 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Schuchart Aaron | Chief Business Officer | A Award deriv | 2017-08-22 | 2017-08-24 | 10,000 | — | $0 | 10,000 | SEC↗ |
| TYLER JOSEPH E | VP, Manufacturing | A Award deriv | 2017-08-22 | 2017-08-24 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Wooldridge James | Chief Medical Officer | A Award deriv | 2017-08-22 | 2017-08-24 | 165,000 | — | $0 | 165,000 | SEC↗ |
| Wooldridge James | Chief Medical Officer | A Award deriv | 2017-08-22 | 2017-08-24 | 10,000 | — | $0 | 10,000 | SEC↗ |
| York Charles N II | Chief Financial Officer and | A Award deriv | 2017-08-22 | 2017-08-24 | 58,500 | — | $0 | 58,500 | SEC↗ |
| York Charles N II | Chief Financial Officer and | P Buy | 2017-08-15 | 2017-12-05 | 1,959 | $2.52 | $4.9K | 14,787 | SEC↗ |
| Schuchart Aaron | Chief Business Officer | A Award deriv | 2017-06-16 | 2017-06-20 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Quinn Anthony | interim Chief Medical Office | A Award deriv | 2017-04-21 | 2017-04-25 | 24,000 | — | $0 | 24,000 | SEC↗ |
| Hebel Henry | VP, Product Development | A Award deriv | 2017-03-20 | 2017-03-22 | 38,200 | — | $0 | 38,200 | SEC↗ |
| Lowe David George | CEO and President | A Award deriv | 2017-03-20 | 2017-03-22 | 160,000 | — | $0 | 160,000 | SEC↗ |
| Rowlinson Scott W | VP, Research | A Award deriv | 2017-03-20 | 2017-03-22 | 60,000 | — | $0 | 60,000 | SEC↗ |
| TYLER JOSEPH E | VP, Manufacturing | A Award deriv | 2017-03-20 | 2017-03-22 | 39,000 | — | $0 | 39,000 | SEC↗ |
| York Charles N II | Chief Financial Officer and | A Award deriv | 2017-03-20 | 2017-03-22 | 90,000 | — | $0 | 90,000 | SEC↗ |
| ORBIMED ADVISORS LLC | 10% Owner | P Buy | 2017-02-21 | 2017-02-21 | 7,000 | $5.36 | $37.5K | 1,469,524 | SEC↗ |
| ORBIMED ADVISORS LLC | 10% Owner | P Buy | 2017-02-17 | 2017-02-21 | 71,800 | $5.19 | $372.6K | 1,462,524 | SEC↗ |
| ORBIMED ADVISORS LLC | 10% Owner | P Buy | 2017-02-16 | 2017-02-21 | 30,500 | $5.04 | $153.7K | 1,390,724 | SEC↗ |
| York Charles N II | Chief Financial Officer and | P Buy | 2017-02-15 | 2017-12-05 | 2,000 | $4.28 | $8.6K | 12,828 | SEC↗ |
| Bruhn Suzanne Louise | Director | A Award deriv | 2017-02-15 | 2017-02-16 | 82,000 | — | $0 | 82,000 | SEC↗ |
| York Charles N II | Chief Financial Officer and | P Buy | 2016-08-15 | 2017-12-05 | 2,000 | $3.99 | $8.0K | 10,828 | SEC↗ |
| Cox Russell J. | Director | A Award deriv | 2016-05-17 | 2016-05-19 | 10,000 | — | $0 | 10,000 | SEC↗ |
| GEORGIOU GEORGE | Director | A Award deriv | 2016-05-17 | 2016-05-19 | 24,000 | — | $0 | 24,000 | SEC↗ |
| Hebel Henry | VP, Product Development | A Award deriv | 2016-05-17 | 2016-05-19 | 43,000 | — | $0 | 43,000 | SEC↗ |
| Lowe David George | CEO and President | A Award deriv | 2016-05-17 | 2016-05-19 | 160,000 | — | $0 | 160,000 | SEC↗ |
| Mahatme Sandesh | Director | A Award deriv | 2016-05-17 | 2016-05-19 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Rojas-Caro Sandra | Chief Medical Officer | A Award deriv | 2016-05-17 | 2016-05-19 | 200,000 | — | $0 | 200,000 | SEC↗ |
| Rowlinson Scott W | VP, Research | A Award deriv | 2016-05-17 | 2016-05-19 | 47,000 | — | $0 | 47,000 | SEC↗ |
| Shanafelt Armen | Director, 10% Owner | A Award deriv | 2016-05-17 | 2016-05-19 | 24,000 | — | $0 | 24,000 | SEC↗ |
| TYLER JOSEPH E | VP, Manufacturing | A Award deriv | 2016-05-17 | 2016-05-19 | 33,000 | — | $0 | 33,000 | SEC↗ |
| York Charles N II | Chief Financial Officer and | A Award deriv | 2016-05-17 | 2016-05-19 | 55,000 | — | $0 | 55,000 | SEC↗ |
| Lowe David George | CEO and President | C Conversion deriv | 2016-04-12 | 2016-04-12 | 2,801 | — | $0 | 0 | SEC↗ |
| Lowe David George | CEO and President | C Conversion deriv | 2016-04-12 | 2016-04-12 | 2,857 | — | $0 | 0 | SEC↗ |
| NOVARTIS AG | 10% Owner | C Conversion deriv | 2016-04-12 | 2016-04-12 | 1,120,448 | — | $0 | 0 | SEC↗ |
| NOVARTIS AG | 10% Owner | C Conversion deriv | 2016-04-12 | 2016-04-12 | 890,476 | — | $0 | 0 | SEC↗ |
| Rowlinson Scott W | VP, Research | C Conversion deriv | 2016-04-12 | 2016-04-12 | 11,204 | — | $0 | 0 | SEC↗ |
| TYLER JOSEPH E | VP, Manufacturing | C Conversion deriv | 2016-04-12 | 2016-04-12 | 8,403 | — | $0 | 0 | SEC↗ |
| TYLER JOSEPH E | VP, Manufacturing | C Conversion deriv | 2016-04-12 | 2016-04-12 | 22,857 | — | $0 | 0 | SEC↗ |
| York Charles N II | Chief Financial Officer and | C Conversion deriv | 2016-04-12 | 2016-04-12 | 1,324 | — | $0 | 0 | SEC↗ |
| York Charles N II | Chief Financial Officer and | C Conversion deriv | 2016-04-12 | 2016-04-12 | 9,523 | — | $0 | 0 | SEC↗ |
| York Charles N II | Chief Financial Officer and | C Conversion deriv | 2016-04-12 | 2016-04-12 | 2,037 | — | $0 | 0 | SEC↗ |
| LILLY ELI & CO | 10% Owner | C Conversion deriv | 2016-04-12 | 2016-04-14 | 1,120,448 | — | $0 | 0 | SEC↗ |
| LILLY ELI & CO | 10% Owner | C Conversion deriv | 2016-04-12 | 2016-04-14 | 890,476 | — | $0 | 0 | SEC↗ |
| Cox Russell J. | Director | P Buy | 2016-04-12 | 2016-04-12 | 7,000 | $10.00 | $70.0K | 7,000 | SEC↗ |
| Lowe David George | CEO and President | C Conversion | 2016-04-12 | 2016-04-12 | 5,658 | — | $0 | 5,658 | SEC↗ |
| NOVARTIS AG | 10% Owner | P Buy | 2016-04-12 | 2016-04-12 | 300,000 | $10.00 | $3.00M | 2,310,924 | SEC↗ |
| NOVARTIS AG | 10% Owner | C Conversion | 2016-04-12 | 2016-04-12 | 2,010,924 | — | $0 | 2,010,924 | SEC↗ |
| Quinn Anthony | Director | P Buy | 2016-04-12 | 2016-04-12 | 10,000 | $10.00 | $100.0K | 10,000 | SEC↗ |
| Rowlinson Scott W | VP, Research | C Conversion | 2016-04-12 | 2016-04-12 | 11,204 | — | $0 | 11,204 | SEC↗ |
| TYLER JOSEPH E | VP, Manufacturing | C Conversion | 2016-04-12 | 2016-04-12 | 31,260 | — | $0 | 42,428 | SEC↗ |
| York Charles N II | Chief Financial Officer and | C Conversion | 2016-04-12 | 2016-04-12 | 1,324 | — | $0 | 8,828 | SEC↗ |
| York Charles N II | Chief Financial Officer and | C Conversion | 2016-04-12 | 2016-04-12 | 11,560 | — | $0 | 11,560 | SEC↗ |
| LILLY ELI & CO | 10% Owner | C Conversion | 2016-04-12 | 2016-04-14 | 2,010,924 | — | $0 | 2,068,543 | SEC↗ |
| LILLY ELI & CO | 10% Owner | P Buy | 2016-04-12 | 2016-04-14 | 500,000 | $10.00 | $5.00M | 2,568,543 | SEC↗ |
| Shanafelt Armen | 10% Owner | C Conversion | 2016-04-12 | 2016-04-14 | 2,010,924 | — | $0 | 2,068,543 | SEC↗ |