Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$0
Insiders on file
30
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Alesina Susan | Director | 2 | $0 | $0 | 2023-03-02 |
| Stephenson Pamela | Chief Commercial Officer | 33 | $0 | $286.4K | 2023-03-02 |
| Okey Stephanie | Director | 12 | $0 | $0 | 2023-03-02 |
| Duncan Jason | General Counsel | 59 | $0 | $1.03M | 2023-03-02 |
| Hopkinson Craig C. | Director | 2 | $0 | $0 | 2023-03-02 |
| STRECK PAUL | Chief Medical Officer | 4 | $0 | $0 | 2023-03-02 |
| Dable Habib J | Director | 2 | $0 | $0 | 2023-03-02 |
| Mattsson Jan | Chief Scientific Officer | 44 | $0 | $3.76M | 2023-03-02 |
| Gutch Michael | Director | 14 | $0 | $0 | 2023-03-02 |
| Chiswell David | Director | 16 | $0 | $0 | 2023-03-02 |
| Cooper Ronald Harold Wilfred | President and CEO | 36 | $50.8K | $226.9K | 2023-03-02 |
| Graham Michelle | Chief Human Resources Officer | 18 | $0 | $100.7K | 2023-03-02 |
| Harford Simon N.R. | CFO and Treasurer | 34 | $0 | $138.7K | 2023-03-02 |
| SCOON DAVEY | Director | 16 | $0 | $0 | 2023-03-02 |
| Carter Martha J. | Chief Regulatory Officer | 47 | $0 | $1.73M | 2023-03-02 |
| PERCEPTIVE ADVISORS LLC | 10% Owner | 8 | $16.00M | $9.51M | 2022-10-13 |
| Horn Patrick Taylor | Chief Medical Officer | 14 | $0 | $30.3K | 2021-10-22 |
| Klibanski Anne | Director | 5 | $0 | $0 | 2021-06-24 |
| JEFFS ROGER | Director | 6 | $0 | $0 | 2021-06-24 |
| PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | 10% Owner | 1 | $5.37M | $0 | 2020-02-03 |
| Shea Thomas A. | CFO and Treasurer | 4 | $0 | $0 | 2018-06-08 |
| Soni Paresh | Chief Medical Officer | 4 | $0 | $0 | 2018-06-08 |
| BROWN JULIA R | Director | 8 | $0 | $0 | 2018-06-07 |
| PHASE4 VENTURES III GENERAL PARTNER Ltd | 10% Owner | 2 | $0 | $3.44M | 2018-01-30 |
| PHASE4 VENTURES III LP | 10% Owner | 2 | $0 | $3.44M | 2018-01-30 |
| EDELMAN JOSEPH | 10% Owner | 1 | $9.07M | $0 | 2018-01-25 |
| ASTRAZENECA AB | 10% Owner | 1 | $0 | $10.70M | 2017-12-01 |
| Zorn Peter A | Senior VP, Corp Dev, GC & Sec | 4 | $0 | $0 | 2017-08-21 |
| Pollard-Knight Denise | Director, 10% Owner | 3 | $0 | $0 | 2017-06-16 |
| Preston Heather | Director | 1 | $0 | $0 | 2017-01-23 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Hopkinson Craig C. | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 10,495 | — | $0 | 0 | SEC↗ |
| SCOON DAVEY | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 3,000 | — | $0 | 0 | SEC↗ |
| SCOON DAVEY | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 8,000 | — | $0 | 0 | SEC↗ |
| SCOON DAVEY | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 8,000 | — | $0 | 0 | SEC↗ |
| SCOON DAVEY | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 8,000 | — | $0 | 0 | SEC↗ |
| SCOON DAVEY | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 5,500 | — | $0 | 0 | SEC↗ |
| SCOON DAVEY | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 5,500 | — | $0 | 0 | SEC↗ |
| SCOON DAVEY | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 3,333 | — | $0 | 0 | SEC↗ |
| SCOON DAVEY | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 333 | — | $0 | 0 | SEC↗ |
| SCOON DAVEY | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 4,500 | — | $0 | 0 | SEC↗ |
| Dable Habib J | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 16,000 | — | $0 | 0 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 20,000 | — | $0 | 0 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 73,950 | — | $0 | 0 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 23,700 | — | $0 | 0 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 31,500 | — | $0 | 0 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 31,500 | — | $0 | 0 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 40,000 | — | $0 | 0 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 13,000 | — | $0 | 0 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | D To issuer deriv | 2023-03-02 | 2023-03-02 | 37,500 | — | $0 | 0 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | D To issuer deriv | 2023-03-02 | 2023-03-02 | 15,900 | — | $0 | 0 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | D To issuer deriv | 2023-03-02 | 2023-03-02 | 65,850 | — | $0 | 0 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | D To issuer deriv | 2023-03-02 | 2023-03-02 | 23,700 | — | $0 | 0 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | D To issuer deriv | 2023-03-02 | 2023-03-02 | 24,337 | — | $0 | 0 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | D To issuer deriv | 2023-03-02 | 2023-03-02 | 10,063 | — | $0 | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 31,500 | — | $0 | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 19,688 | — | $0 | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 2,500 | — | $0 | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 30,000 | — | $0 | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 62,009 | — | $0 | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 65,850 | — | $0 | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 15,900 | — | $0 | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 3,250 | — | $0 | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 23,700 | — | $0 | 0 | SEC↗ |
| Gutch Michael | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 5,500 | — | $0 | 0 | SEC↗ |
| Gutch Michael | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 8,000 | — | $0 | 0 | SEC↗ |
| Gutch Michael | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 8,000 | — | $0 | 0 | SEC↗ |
| Gutch Michael | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 4,500 | — | $0 | 0 | SEC↗ |
| Gutch Michael | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 3,000 | — | $0 | 0 | SEC↗ |
| Gutch Michael | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 5,500 | — | $0 | 0 | SEC↗ |
| Gutch Michael | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 8,000 | — | $0 | 0 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | D To issuer deriv | 2023-03-02 | 2023-03-02 | 37,500 | — | $0 | 0 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | D To issuer deriv | 2023-03-02 | 2023-03-02 | 23,700 | — | $0 | 0 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | D To issuer deriv | 2023-03-02 | 2023-03-02 | 50,950 | — | $0 | 0 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | D To issuer deriv | 2023-03-02 | 2023-03-02 | 31,500 | — | $0 | 0 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 23,700 | — | $0 | 0 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 31,500 | — | $0 | 0 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 37,500 | — | $0 | 0 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 75,513 | — | $0 | 0 | SEC↗ |
| STRECK PAUL | Chief Medical Officer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 118,966 | — | $0 | 0 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | D To issuer deriv | 2023-03-02 | 2023-03-02 | 123,750 | — | $0 | 0 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | D To issuer deriv | 2023-03-02 | 2023-03-02 | 132,150 | — | $0 | 0 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | D To issuer deriv | 2023-03-02 | 2023-03-02 | 219,350 | — | $0 | 0 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | D To issuer deriv | 2023-03-02 | 2023-03-02 | 155,381 | — | $0 | 0 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | D To issuer deriv | 2023-03-02 | 2023-03-02 | 19,422 | — | $0 | 0 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | D To issuer deriv | 2023-03-02 | 2023-03-02 | 60,000 | — | $0 | 0 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | D To issuer deriv | 2023-03-02 | 2023-03-02 | 124,000 | — | $0 | 0 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | D To issuer deriv | 2023-03-02 | 2023-03-02 | 124,000 | — | $0 | 0 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | D To issuer deriv | 2023-03-02 | 2023-03-02 | 93,000 | — | $0 | 0 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | D To issuer deriv | 2023-03-02 | 2023-03-02 | 43,027 | — | $0 | 0 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 23,700 | — | $0 | 0 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 73,950 | — | $0 | 0 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 37,500 | — | $0 | 0 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 31,500 | — | $0 | 0 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | D To issuer deriv | 2023-03-02 | 2023-03-02 | 31,500 | — | $0 | 0 | SEC↗ |
| Okey Stephanie | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 8,000 | — | $0 | 0 | SEC↗ |
| Okey Stephanie | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 8,000 | — | $0 | 0 | SEC↗ |
| Okey Stephanie | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 8,000 | — | $0 | 0 | SEC↗ |
| Okey Stephanie | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 5,500 | — | $0 | 0 | SEC↗ |
| Okey Stephanie | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 5,500 | — | $0 | 0 | SEC↗ |
| Okey Stephanie | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 11,000 | — | $0 | 0 | SEC↗ |
| Alesina Susan | Director | D To issuer deriv | 2023-03-02 | 2023-03-02 | 16,000 | — | $0 | 0 | SEC↗ |
| Chiswell David | Director | D To issuer deriv | 2023-03-02 | 2023-03-03 | 5,500 | — | $0 | 0 | SEC↗ |
| Chiswell David | Director | D To issuer deriv | 2023-03-02 | 2023-03-03 | 3,000 | — | $0 | 0 | SEC↗ |
| Chiswell David | Director | D To issuer deriv | 2023-03-02 | 2023-03-03 | 5,500 | — | $0 | 0 | SEC↗ |
| Chiswell David | Director | D To issuer deriv | 2023-03-02 | 2023-03-03 | 4,500 | — | $0 | 0 | SEC↗ |
| Chiswell David | Director | D To issuer deriv | 2023-03-02 | 2023-03-03 | 8,000 | — | $0 | 0 | SEC↗ |
| Chiswell David | Director | D To issuer deriv | 2023-03-02 | 2023-03-03 | 8,000 | — | $0 | 0 | SEC↗ |
| Chiswell David | Director | D To issuer deriv | 2023-03-02 | 2023-03-03 | 8,000 | — | $0 | 0 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | U Tender | 2023-03-02 | 2023-03-02 | 35,524 | — | $0 | 0 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | U Tender | 2023-03-02 | 2023-03-02 | 3,296 | — | $0 | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | U Tender | 2023-03-02 | 2023-03-02 | 3,656 | — | $0 | 3,654 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | U Tender | 2023-03-02 | 2023-03-02 | 5,543 | — | $0 | 0 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | U Tender | 2023-03-02 | 2023-03-02 | 22,242 | — | $0 | 0 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | U Tender | 2023-03-02 | 2023-03-02 | 33,094 | — | $0 | 0 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | U Tender | 2023-03-02 | 2023-03-02 | 13,739 | — | $0 | 0 | SEC↗ |
| Chiswell David | Director | U Tender | 2023-03-02 | 2023-03-03 | 56,278 | — | $0 | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | S Sale | 2023-01-23 | 2023-01-23 | 120 | $43.80 | $5.3K | 14,506 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | S Sale | 2023-01-23 | 2023-01-23 | 1,057 | $43.80 | $46.3K | 57,444 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2023-01-23 | 2023-01-23 | 228 | $43.80 | $10.0K | 14,146 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2023-01-23 | 2023-01-23 | 102 | $43.80 | $4.5K | 32,689 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2023-01-23 | 2023-01-23 | 197 | $43.80 | $8.6K | 54,474 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | S Sale | 2023-01-23 | 2023-01-23 | 102 | $43.80 | $4.5K | 24,493 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2023-01-23 | 2023-01-23 | 102 | $43.80 | $4.5K | 42,755 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2023-01-19 | 2023-01-20 | 1,776 | $43.80 | $77.8K | 32,791 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | S Sale | 2023-01-19 | 2023-01-20 | 1,774 | $43.90 | $77.9K | 24,595 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2023-01-19 | 2023-01-20 | 3,088 | $43.80 | $135.3K | 54,671 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2023-01-19 | 2023-01-20 | 938 | $43.90 | $41.2K | 14,374 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | S Sale | 2023-01-19 | 2023-01-20 | 938 | $43.90 | $41.2K | 14,626 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2023-01-19 | 2023-01-20 | 1,774 | $43.90 | $77.9K | 42,857 | SEC↗ |
| STRECK PAUL | Chief Medical Officer | A Award | 2023-01-19 | 2023-01-25 | 55,000 | — | $0 | 118,966 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | A Award | 2023-01-19 | 2023-01-25 | 55,000 | — | $0 | 97,755 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | A Award | 2023-01-19 | 2023-01-25 | 55,000 | — | $0 | 87,689 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | A Award | 2023-01-19 | 2023-01-25 | 32,000 | — | $0 | 56,493 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | A Award | 2023-01-19 | 2023-01-25 | 55,000 | — | $0 | 69,146 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | A Award | 2023-01-19 | 2023-01-25 | 55,000 | — | $0 | 69,506 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | A Award | 2023-01-19 | 2023-01-25 | 55,000 | — | $0 | 109,474 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | A Award | 2023-01-19 | 2023-01-25 | 195,000 | — | $0 | 252,444 | SEC↗ |
| STRECK PAUL | Chief Medical Officer | A Award | 2023-01-19 | 2023-01-27 | 55,000 | — | $0 | 118,966 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | A Award | 2023-01-19 | 2023-01-27 | 55,000 | — | $0 | 97,755 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | A Award | 2023-01-19 | 2023-01-27 | 55,000 | — | $0 | 87,689 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | A Award | 2023-01-19 | 2023-01-27 | 32,000 | — | $0 | 56,493 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | A Award | 2023-01-19 | 2023-01-27 | 55,000 | — | $0 | 69,146 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | A Award | 2023-01-19 | 2023-01-27 | 55,000 | — | $0 | 69,506 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | A Award | 2023-01-19 | 2023-01-27 | 55,000 | — | $0 | 109,474 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | A Award | 2023-01-19 | 2023-01-27 | 195,000 | — | $0 | 252,444 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2022-12-27 | 2023-01-09 | 469 | $19.06 | $8.9K | 44,631 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2022-12-27 | 2022-12-27 | 469 | $19.06 | $8.9K | 45,178 | SEC↗ |
| STRECK PAUL | Chief Medical Officer | A Award | 2022-12-19 | 2022-12-21 | 63,966 | — | $0 | 63,966 | SEC↗ |
| Hopkinson Craig C. | Director | A Award | 2022-12-01 | 2022-12-05 | 10,495 | — | $0 | 10,495 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | S Sale | 2022-10-24 | 2023-01-09 | 919 | $19.58 | $18.0K | 58,501 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | S Sale | 2022-10-24 | 2022-10-25 | 919 | $19.58 | $18.0K | 55,461 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | S Sale | 2022-10-24 | 2022-10-25 | 104 | $19.58 | $2.0K | 15,564 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2022-10-24 | 2022-10-25 | 104 | $19.58 | $2.0K | 33,295 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | S Sale | 2022-10-24 | 2022-10-25 | 104 | $19.58 | $2.0K | 26,369 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2022-10-24 | 2022-10-25 | 202 | $19.58 | $4.0K | 57,759 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-10-24 | 2022-10-25 | 456 | $19.40 | $8.8K | 14,931 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-10-24 | 2022-10-25 | 96 | $19.54 | $1.9K | 15,387 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-10-24 | 2022-10-25 | 104 | $19.58 | $2.0K | 15,483 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2022-10-24 | 2022-10-25 | 104 | $19.58 | $2.0K | 45,647 | SEC↗ |
| PERCEPTIVE ADVISORS LLC | 10% Owner | S Sale | 2022-10-13 | 2022-10-13 | 178,726 | $22.01 | $3.93M | 1,940,129 | SEC↗ |
| PERCEPTIVE ADVISORS LLC | 10% Owner | S Sale | 2022-10-13 | 2022-10-13 | 406 | $22.79 | $9.3K | 1,939,723 | SEC↗ |
| PERCEPTIVE ADVISORS LLC | 10% Owner | S Sale | 2022-10-12 | 2022-10-13 | 89,979 | $22.26 | $2.00M | 2,126,095 | SEC↗ |
| PERCEPTIVE ADVISORS LLC | 10% Owner | S Sale | 2022-10-12 | 2022-10-13 | 7,240 | $23.23 | $168.2K | 2,118,855 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2022-10-11 | 2022-10-13 | 80 | $23.79 | $1.9K | 33,399 | SEC↗ |
| PERCEPTIVE ADVISORS LLC | 10% Owner | S Sale | 2022-10-11 | 2022-10-13 | 38,310 | $24.18 | $926.3K | 2,221,489 | SEC↗ |
| PERCEPTIVE ADVISORS LLC | 10% Owner | S Sale | 2022-10-11 | 2022-10-13 | 5,415 | $24.78 | $134.2K | 2,216,074 | SEC↗ |
| PERCEPTIVE ADVISORS LLC | 10% Owner | S Sale | 2022-10-11 | 2022-10-13 | 100,340 | $23.23 | $2.33M | 2,259,799 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2022-09-26 | 2022-09-27 | 445 | $19.40 | $8.6K | 45,751 | SEC↗ |
| Alesina Susan | Director | A Award deriv | 2022-08-08 | 2022-08-10 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Dable Habib J | Director | A Award deriv | 2022-08-08 | 2022-08-10 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-07-25 | 2022-07-25 | 93 | $24.40 | $2.3K | 15,807 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-07-25 | 2022-07-25 | 220 | $23.66 | $5.2K | 15,587 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2022-07-22 | 2023-01-09 | 106 | $24.67 | $2.6K | 45,649 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | S Sale | 2022-07-22 | 2022-07-25 | 929 | $24.67 | $22.9K | 56,380 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-07-22 | 2022-07-25 | 238 | $24.45 | $5.8K | 15,900 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-07-22 | 2022-07-25 | 106 | $24.68 | $2.6K | 16,138 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2022-07-22 | 2022-07-25 | 106 | $24.67 | $2.6K | 46,196 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2022-07-22 | 2022-07-25 | 106 | $24.67 | $2.6K | 33,479 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | S Sale | 2022-07-22 | 2022-07-25 | 106 | $24.67 | $2.6K | 26,473 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | S Sale | 2022-07-22 | 2022-07-25 | 106 | $24.68 | $2.6K | 15,668 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2022-07-22 | 2022-07-25 | 205 | $24.68 | $5.1K | 57,961 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2022-07-12 | 2022-07-13 | 95 | $24.03 | $2.3K | 33,585 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2022-06-27 | 2022-06-28 | 461 | $19.47 | $9.0K | 45,755 | SEC↗ |
| Chiswell David | Director | A Award deriv | 2022-06-24 | 2022-06-28 | 8,000 | — | $0 | 8,000 | SEC↗ |
| Gutch Michael | Director | A Award deriv | 2022-06-24 | 2022-06-28 | 8,000 | — | $0 | 8,000 | SEC↗ |
| Okey Stephanie | Director | A Award deriv | 2022-06-24 | 2022-06-28 | 8,000 | — | $0 | 8,000 | SEC↗ |
| SCOON DAVEY | Director | A Award deriv | 2022-06-24 | 2022-06-28 | 8,000 | — | $0 | 8,000 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-04-25 | 2022-04-25 | 221 | $33.44 | $7.4K | 16,099 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-04-25 | 2022-04-25 | 91 | $33.40 | $3.0K | 16,008 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-04-22 | 2022-04-25 | 103 | $32.93 | $3.4K | 16,320 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-04-22 | 2022-04-25 | 240 | $33.07 | $7.9K | 16,423 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | S Sale | 2022-04-22 | 2022-04-25 | 907 | $33.11 | $30.0K | 56,082 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2022-04-22 | 2022-04-25 | 103 | $32.92 | $3.4K | 46,216 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2022-04-22 | 2022-04-25 | 103 | $32.92 | $3.4K | 33,680 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2022-04-22 | 2022-04-25 | 200 | $32.92 | $6.6K | 58,166 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | S Sale | 2022-04-22 | 2022-04-25 | 103 | $32.92 | $3.4K | 26,579 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | S Sale | 2022-04-22 | 2022-04-25 | 103 | $32.92 | $3.4K | 15,774 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2022-04-11 | 2022-04-11 | 96 | $35.74 | $3.4K | 33,783 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2022-03-28 | 2022-03-29 | 454 | $30.53 | $13.9K | 46,319 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | S Sale | 2022-01-24 | 2022-01-25 | 418 | $24.72 | $10.3K | 26,682 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | S Sale | 2022-01-24 | 2022-01-25 | 423 | $24.52 | $10.4K | 15,877 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | S Sale | 2022-01-24 | 2022-01-25 | 3,684 | $24.88 | $91.7K | 56,989 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2022-01-24 | 2022-01-25 | 808 | $24.88 | $20.1K | 58,366 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2022-01-24 | 2022-01-25 | 416 | $24.88 | $10.4K | 46,773 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2022-01-24 | 2022-01-25 | 416 | $24.88 | $10.4K | 33,879 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-01-24 | 2022-01-25 | 416 | $24.88 | $10.4K | 17,935 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-01-24 | 2022-01-25 | 96 | $25.09 | $2.4K | 17,839 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2022-01-24 | 2022-01-25 | 1,176 | $24.94 | $29.3K | 16,663 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | A Award deriv | 2022-01-18 | 2022-01-20 | 132,150 | — | $0 | 132,150 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | A Award deriv | 2022-01-18 | 2022-01-20 | 15,900 | — | $0 | 15,900 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | A Award deriv | 2022-01-18 | 2022-01-20 | 15,900 | — | $0 | 15,900 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | A Award | 2022-01-18 | 2022-01-20 | 21,600 | — | $0 | 47,189 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | A Award | 2022-01-18 | 2022-01-20 | 10,800 | — | $0 | 18,351 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | A Award | 2022-01-18 | 2022-01-20 | 21,600 | — | $0 | 34,295 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | A Award | 2022-01-18 | 2022-01-20 | 21,600 | — | $0 | 27,100 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | A Award | 2022-01-18 | 2022-01-20 | 10,800 | — | $0 | 16,300 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | A Award | 2022-01-18 | 2022-01-20 | 21,600 | — | $0 | 59,174 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2022-01-11 | 2022-01-11 | 111 | $25.95 | $2.9K | 12,695 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2021-12-27 | 2021-12-27 | 474 | $23.92 | $11.3K | 25,589 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2021-10-25 | 2021-10-25 | 217 | $29.21 | $6.3K | 7,355 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2021-10-22 | 2021-10-25 | 95 | $28.85 | $2.7K | 7,572 | SEC↗ |
| Horn Patrick Taylor | Chief Medical Officer | S Sale | 2021-10-22 | 2021-10-25 | 95 | $28.83 | $2.7K | 12,355 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2021-10-11 | 2021-10-12 | 93 | $30.23 | $2.8K | 12,614 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2021-09-27 | 2021-09-28 | 451 | $32.05 | $14.5K | 26,063 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | M Exercise deriv | 2021-09-17 | 2021-09-20 | 11,973 | — | $0 | 43,027 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | M Exercise | 2021-09-17 | 2021-09-20 | 11,973 | $19.19 | $229.8K | 68,433 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | F Tax w/h | 2021-09-17 | 2021-09-20 | 7,760 | $29.61 | $229.8K | 60,673 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2021-07-23 | 2021-07-26 | 223 | $31.43 | $7.0K | 7,667 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2021-07-22 | 2021-07-26 | 90 | $34.13 | $3.1K | 7,890 | SEC↗ |
| Horn Patrick Taylor | Chief Medical Officer | S Sale | 2021-07-22 | 2021-07-26 | 90 | $34.13 | $3.1K | 12,450 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2021-07-13 | 2021-07-15 | 98 | $35.02 | $3.4K | 12,707 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | M Exercise deriv | 2021-06-25 | 2021-06-28 | 6,300 | — | $0 | 24,337 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | M Exercise | 2021-06-25 | 2021-06-28 | 6,300 | $24.67 | $155.4K | 14,280 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2021-06-25 | 2021-06-28 | 6,300 | $36.22 | $228.2K | 7,980 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2021-06-25 | 2021-06-28 | 471 | $36.01 | $17.0K | 26,514 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | M Exercise deriv | 2021-06-24 | 2021-06-28 | 9,137 | — | $0 | 10,063 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | M Exercise deriv | 2021-06-24 | 2021-06-28 | 863 | — | $0 | 30,637 | SEC↗ |
| Chiswell David | Director | A Award deriv | 2021-06-24 | 2021-06-28 | 8,000 | — | $0 | 8,000 | SEC↗ |
| Gutch Michael | Director | A Award deriv | 2021-06-24 | 2021-06-28 | 8,000 | — | $0 | 8,000 | SEC↗ |
| JEFFS ROGER | Director | A Award deriv | 2021-06-24 | 2021-06-28 | 8,000 | — | $0 | 8,000 | SEC↗ |
| SCOON DAVEY | Director | A Award deriv | 2021-06-24 | 2021-06-28 | 8,000 | — | $0 | 8,000 | SEC↗ |
| Okey Stephanie | Director | A Award deriv | 2021-06-24 | 2021-06-28 | 8,000 | — | $0 | 8,000 | SEC↗ |
| Klibanski Anne | Director | A Award deriv | 2021-06-24 | 2021-06-28 | 8,000 | — | $0 | 8,000 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2021-06-24 | 2021-06-28 | 10,000 | $36.38 | $363.8K | 7,980 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | M Exercise | 2021-06-24 | 2021-06-28 | 9,137 | $24.04 | $219.7K | 17,117 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | M Exercise | 2021-06-24 | 2021-06-28 | 863 | $24.67 | $21.3K | 17,980 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2021-04-23 | 2021-04-26 | 222 | $32.32 | $7.2K | 7,849 | SEC↗ |
| Horn Patrick Taylor | Chief Medical Officer | S Sale | 2021-04-22 | 2021-04-26 | 90 | $31.75 | $2.9K | 11,893 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2021-04-22 | 2021-04-26 | 90 | $31.75 | $2.9K | 8,071 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2021-04-12 | 2021-04-14 | 92 | $32.12 | $3.0K | 12,196 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | M Exercise deriv | 2021-04-01 | 2021-04-02 | 300 | — | $0 | 19,200 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | M Exercise | 2021-04-01 | 2021-04-02 | 300 | $24.04 | $7.2K | 8,461 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2021-04-01 | 2021-04-02 | 300 | $36.16 | $10.8K | 8,161 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2021-03-31 | 2021-04-02 | 1,426 | $35.04 | $50.0K | 8,161 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2021-03-29 | 2021-03-31 | 422 | $34.02 | $14.4K | 26,985 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2021-03-03 | 2021-03-03 | 400 | $36.20 | $14.5K | 37,574 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2021-03-03 | 2021-03-05 | 400 | $36.20 | $14.5K | 37,574 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2021-03-02 | 2021-03-03 | 612 | $36.54 | $22.4K | 40,781 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2021-03-02 | 2021-03-03 | 12,351 | $36.07 | $445.5K | 41,393 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2021-03-02 | 2021-03-03 | 2,807 | $37.15 | $104.3K | 37,974 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2021-03-02 | 2021-03-05 | 612 | $36.54 | $22.4K | 40,781 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2021-03-02 | 2021-03-05 | 2,807 | $37.15 | $104.3K | 37,974 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2021-03-02 | 2021-03-05 | 12,351 | $36.07 | $445.5K | 41,393 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | M Exercise deriv | 2021-03-01 | 2021-03-03 | 39,330 | — | $0 | 0 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | M Exercise deriv | 2021-03-01 | 2021-03-05 | 39,330 | — | $0 | 0 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | M Exercise | 2021-03-01 | 2021-03-03 | 39,330 | $1.00 | $39.3K | 69,044 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2021-03-01 | 2021-03-03 | 15,300 | $37.45 | $573.0K | 53,744 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | M Exercise | 2021-03-01 | 2021-03-05 | 39,330 | $1.00 | $39.3K | 69,044 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2021-03-01 | 2021-03-05 | 15,300 | $37.45 | $573.0K | 53,744 | SEC↗ |
| Horn Patrick Taylor | Chief Medical Officer | S Sale | 2021-01-22 | 2021-01-25 | 110 | $34.62 | $3.8K | 9,825 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2021-01-22 | 2021-01-25 | 110 | $34.62 | $3.8K | 9,332 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | A Award deriv | 2021-01-21 | 2021-01-25 | 93,000 | — | $0 | 93,000 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | A Award deriv | 2021-01-21 | 2021-01-25 | 23,700 | — | $0 | 23,700 | SEC↗ |
| Horn Patrick Taylor | Chief Medical Officer | A Award deriv | 2021-01-21 | 2021-01-25 | 23,700 | — | $0 | 23,700 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | A Award deriv | 2021-01-21 | 2021-01-25 | 23,700 | — | $0 | 23,700 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | A Award deriv | 2021-01-21 | 2021-01-25 | 23,700 | — | $0 | 23,700 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | A Award deriv | 2021-01-21 | 2021-01-25 | 23,700 | — | $0 | 23,700 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | A Award deriv | 2021-01-21 | 2021-01-25 | 23,700 | — | $0 | 23,700 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | A Award deriv | 2021-01-21 | 2021-01-25 | 23,700 | — | $0 | 23,700 | SEC↗ |
| Cooper Ronald Harold Wilfred | President and CEO | A Award | 2021-01-21 | 2021-01-25 | 48,700 | — | $0 | 56,460 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | A Award | 2021-01-21 | 2021-01-25 | 5,500 | — | $0 | 27,407 | SEC↗ |
| Horn Patrick Taylor | Chief Medical Officer | A Award | 2021-01-21 | 2021-01-25 | 5,500 | — | $0 | 9,935 | SEC↗ |
| Graham Michelle | Chief Human Resources Office | A Award | 2021-01-21 | 2021-01-25 | 5,500 | — | $0 | 5,500 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | A Award | 2021-01-21 | 2021-01-25 | 5,500 | — | $0 | 5,500 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | A Award | 2021-01-21 | 2021-01-25 | 5,500 | — | $0 | 29,714 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | A Award | 2021-01-21 | 2021-01-25 | 5,500 | — | $0 | 9,442 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | A Award | 2021-01-21 | 2021-01-25 | 5,500 | — | $0 | 10,114 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2021-01-11 | 2021-01-13 | 110 | $37.33 | $4.1K | 4,614 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2021-01-11 | 2021-01-25 | 110 | $37.33 | $4.1K | 4,614 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2020-12-28 | 2020-12-29 | 460 | $39.07 | $18.0K | 21,907 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2020-10-22 | 2020-10-23 | 89 | $34.71 | $3.1K | 3,781 | SEC↗ |
| Horn Patrick Taylor | Chief Medical Officer | S Sale | 2020-10-22 | 2020-10-23 | 89 | $34.55 | $3.1K | 4,285 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2020-10-12 | 2020-10-13 | 90 | $37.30 | $3.4K | 4,616 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2020-09-25 | 2020-09-25 | 451 | $33.20 | $15.0K | 22,367 | SEC↗ |
| PERCEPTIVE ADVISORS LLC | 10% Owner | P Buy | 2020-09-14 | 2020-09-15 | 400,000 | $40.00 | $16.00M | 2,360,139 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise deriv | 2020-09-11 | 2020-09-15 | 938 | — | $0 | 62,009 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise deriv | 2020-09-11 | 2020-09-15 | 9,062 | — | $0 | 3,250 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | S Sale | 2020-09-11 | 2020-09-15 | 10,000 | $40.03 | $400.3K | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise | 2020-09-11 | 2020-09-15 | 938 | $29.76 | $27.9K | 10,000 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise | 2020-09-11 | 2020-09-15 | 9,062 | $24.48 | $221.8K | 9,062 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise deriv | 2020-09-10 | 2020-09-10 | 688 | — | $0 | 12,312 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise deriv | 2020-09-10 | 2020-09-10 | 9,312 | — | $0 | 19,688 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | S Sale | 2020-09-10 | 2020-09-10 | 10,000 | $42.41 | $424.1K | 0 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise | 2020-09-10 | 2020-09-10 | 688 | $24.48 | $16.8K | 10,000 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise | 2020-09-10 | 2020-09-10 | 9,312 | $24.04 | $223.9K | 9,312 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise deriv | 2020-09-09 | 2020-09-10 | 7,500 | — | $0 | 2,500 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise deriv | 2020-09-09 | 2020-09-10 | 2,500 | — | $0 | 29,000 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise | 2020-09-09 | 2020-09-10 | 7,500 | $19.19 | $143.9K | 7,500 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise | 2020-09-09 | 2020-09-10 | 2,500 | $24.04 | $60.1K | 10,000 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | S Sale | 2020-09-09 | 2020-09-10 | 7,500 | $38.68 | $290.1K | 2,500 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | S Sale | 2020-09-09 | 2020-09-10 | 2,500 | $39.82 | $99.5K | 0 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | M Exercise deriv | 2020-09-08 | 2020-09-10 | 3,500 | — | $0 | 19,500 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise deriv | 2020-09-08 | 2020-09-10 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Mattsson Jan | Chief Scientific Officer | S Sale | 2020-09-08 | 2020-09-10 | 10,000 | $45.55 | $455.5K | 24,214 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | M Exercise | 2020-09-08 | 2020-09-10 | 3,500 | $24.04 | $84.1K | 7,870 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2020-09-08 | 2020-09-10 | 4,000 | $45.55 | $182.2K | 3,870 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | M Exercise | 2020-09-08 | 2020-09-10 | 10,000 | $19.19 | $191.9K | 10,000 | SEC↗ |
| Carter Martha J. | Chief Regulatory Officer | S Sale | 2020-09-08 | 2020-09-10 | 10,000 | $45.55 | $455.5K | 0 | SEC↗ |
| Horn Patrick Taylor | Chief Medical Officer | S Sale | 2020-07-22 | 2020-07-23 | 91 | $25.80 | $2.3K | 4,374 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2020-07-22 | 2020-07-23 | 91 | $25.80 | $2.3K | 4,370 | SEC↗ |
| Harford Simon N.R. | CFO and Treasurer | S Sale | 2020-07-10 | 2020-07-10 | 92 | $25.56 | $2.4K | 4,706 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2020-06-25 | 2020-06-26 | 397 | $30.79 | $12.2K | 22,818 | SEC↗ |
| Gutch Michael | Director | A Award deriv | 2020-06-19 | 2020-06-19 | 8,000 | — | $0 | 8,000 | SEC↗ |
| JEFFS ROGER | Director | A Award deriv | 2020-06-19 | 2020-06-19 | 8,000 | — | $0 | 8,000 | SEC↗ |
| Klibanski Anne | Director | A Award deriv | 2020-06-19 | 2020-06-19 | 8,000 | — | $0 | 8,000 | SEC↗ |
| Okey Stephanie | Director | A Award deriv | 2020-06-19 | 2020-06-19 | 8,000 | — | $0 | 8,000 | SEC↗ |
| SCOON DAVEY | Director | A Award deriv | 2020-06-19 | 2020-06-19 | 8,000 | — | $0 | 8,000 | SEC↗ |
| Chiswell David | Director | A Award deriv | 2020-06-19 | 2020-06-19 | 8,000 | — | $0 | 8,000 | SEC↗ |
| Duncan Jason | Chief Legal Officer and GC | S Sale | 2020-04-22 | 2020-04-24 | 92 | $17.68 | $1.6K | 4,461 | SEC↗ |
| Horn Patrick Taylor | Chief Medical Officer | S Sale | 2020-04-22 | 2020-04-24 | 92 | $17.64 | $1.6K | 4,465 | SEC↗ |