ANAB

ANAPTYSBIO, INCCIK 1370053 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

—

0 trades · 0 insiders

Open-mkt sales · 90d

$249.4K

1 trades · 1 insiders

Net · 90d

$-249.4K

Insiders on file

AI insights for ANAB PRO

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AI insights for ANAB

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date

Insiders

Insider	Role	Trades	Bought	Sold	Last trade
RENTON HOLLINGS	Director	60	$0	$1.62M	2026-10-01
Orwin John A	Director	34	$0	$0	2026-09-15
Schmid John P.	Director	49	$0	$1.16M	2026-06-15
Murphy Christopher M.	Chief Financial Officer	1	$0	$0	2026-05-11
Hughes Owen	Director	1	$0	$0	2026-05-11
GRAY SUSANNAH	Director	1	$0	$0	2026-04-27
Faga Daniel	President, CEO, Director	62	$0	$6.34M	2026-04-20
Lizzul Paul F.	Chief Medical Officer	53	$0	$895.2K	2026-03-12
LOUMEAU ERIC J	General Counsel & Interim CFO	87	$0	$4.40M	2026-02-11
Marquet Magda	Director	20	$0	$530.6K	2026-01-15
MULROY DENNIS	Chief Financial Officer	52	$0	$2.31M	2026-01-08
Ware J. Anthony	Director	21	$50.6K	$193.4K	2026-01-06
Jain Rita	Director	16	$0	$0	2026-01-06
FENTON DENNIS M	Director	20	$0	$117.5K	2026-01-06
EcoR1 Capital, LLC	Director, 10% Owner	9	$88.93M	$14.45M	2025-01-02
Hamill Laura	Director	7	$0	$0	2023-01-06
Topper James N	Director, 10% Owner	27	$6.00M	$0	2023-01-06
Suria Hamza	President, CEO	72	$0	$15.75M	2022-02-10
NODELMAN OLEG	Director, 10% Owner	6	$8.63M	$0	2021-05-04
Londei Marco	Chief Medical Officer	28	$0	$4.07M	2019-12-06
Piscitelli Dominic	Chief Financial Officer	11	$0	$2.67M	2019-02-08
Lydon Nicholas	Director	17	$250.0K	$2.87M	2019-02-08
Naini Nader J	10% Owner	14	$6.00M	$0	2018-05-11
Schoeneck James A	Director	2	$0	$0	2018-02-02
Gallagher Carol Giltner	Director	5	$0	$0	2018-02-02
Novo Holdings A/S	10% Owner	20	$750.0K	$23.32M	2017-08-21
Tomlin Stephen Lawrence	10% Owner	3	$0	$901.9K	2017-07-26
MOYLE MATTHEW	Chief Scientific Officer	1	$0	$0	2017-02-24
Every Nathan R	10% Owner	2	$0	$0	2017-02-02
FRAZIER ALAN D	10% Owner	2	$0	$0	2017-02-02
Heron Patrick J	10% Owner	12	$6.00M	$0	2017-01-31

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
RENTON HOLLINGS	Director	M Exercise deriv	2026-10-01	2026-10-02	5,000	—	$0	10,000	SEC↗
RENTON HOLLINGS	Director	S Sale	2026-10-01	2026-10-02	5,000	$49.87	$249.4K	10,995	SEC↗
RENTON HOLLINGS	Director	M Exercise	2026-10-01	2026-10-02	5,000	$18.03	$90.2K	15,995	SEC↗
Orwin John A	Director	M Exercise deriv	2026-09-15	2026-09-17	1,300	—	$0	0	SEC↗
Orwin John A	Director	M Exercise	2026-09-15	2026-09-17	1,300	—	$0	17,995	SEC↗
Orwin John A	Director	M Exercise deriv	2026-09-15	2026-09-17	1,300	—	$0	0	SEC↗
Orwin John A	Director	M Exercise	2026-09-15	2026-09-17	1,300	—	$0	17,995	SEC↗
Orwin John A	Director	M Exercise deriv	2026-06-15	2026-06-17	6,030	—	$0	0	SEC↗
RENTON HOLLINGS	Director	M Exercise deriv	2026-06-15	2026-06-17	6,030	—	$0	0	SEC↗
Schmid John P.	Director	M Exercise deriv	2026-06-15	2026-06-17	6,030	—	$0	0	SEC↗
Orwin John A	Director	M Exercise	2026-06-15	2026-06-17	6,030	—	$0	16,695	SEC↗
RENTON HOLLINGS	Director	M Exercise	2026-06-15	2026-06-17	6,030	—	$0	10,995	SEC↗
Schmid John P.	Director	M Exercise	2026-06-15	2026-06-17	6,030	—	$0	37,652	SEC↗
Murphy Christopher M.	Chief Financial Officer	A Award deriv	2026-05-11	2026-05-13	25,765	—	$0	25,765	SEC↗
Hughes Owen	Director	A Award deriv	2026-05-11	2026-05-13	11,250	—	$0	11,250	SEC↗
GRAY SUSANNAH	Director	A Award deriv	2026-04-27	2026-04-29	11,250	—	$0	11,250	SEC↗
Faga Daniel	President, CEO	D To issuer deriv	2026-04-20	2026-04-22	194,900	—	$0	194,900	SEC↗
Faga Daniel	President, CEO	D To issuer deriv	2026-04-20	2026-04-22	133,400	—	$0	133,400	SEC↗
Faga Daniel	President, CEO	A Award deriv	2026-04-20	2026-04-22	305,500	—	$0	305,500	SEC↗
Faga Daniel	President, CEO	D To issuer deriv	2026-04-20	2026-04-22	305,500	—	$0	305,500	SEC↗
Faga Daniel	President, CEO	A Award deriv	2026-04-20	2026-04-22	379,620	—	$0	379,620	SEC↗
Faga Daniel	President, CEO	D To issuer deriv	2026-04-20	2026-04-22	379,620	—	$0	379,620	SEC↗
Faga Daniel	President, CEO	A Award deriv	2026-04-20	2026-04-22	194,900	—	$0	194,900	SEC↗
Faga Daniel	President, CEO	A Award deriv	2026-04-20	2026-04-22	133,400	—	$0	133,400	SEC↗
Faga Daniel	President, CEO	A Award deriv	2026-04-20	2026-04-22	9,200	—	$0	9,200	SEC↗
Faga Daniel	President, CEO	D To issuer deriv	2026-04-20	2026-04-22	9,200	—	$0	9,200	SEC↗
Faga Daniel	President, CEO	A Award deriv	2026-04-20	2026-04-22	2,321	—	$0	2,321	SEC↗
Faga Daniel	President, CEO	D To issuer deriv	2026-04-20	2026-04-22	2,321	—	$0	2,321	SEC↗
Faga Daniel	President, CEO	A Award deriv	2026-04-20	2026-04-22	11,000	—	$0	11,000	SEC↗
Faga Daniel	President, CEO	D To issuer deriv	2026-04-20	2026-04-22	11,000	—	$0	16,510	SEC↗
RENTON HOLLINGS	Director	D To issuer deriv	2026-04-20	2026-04-22	10,600	—	$0	10,600	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2026-04-20	2026-04-22	11,000	—	$0	11,000	SEC↗
RENTON HOLLINGS	Director	D To issuer deriv	2026-04-20	2026-04-22	11,000	—	$0	11,000	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2026-04-20	2026-04-22	11,000	—	$0	11,000	SEC↗
RENTON HOLLINGS	Director	D To issuer deriv	2026-04-20	2026-04-22	11,000	—	$0	11,000	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2026-04-20	2026-04-22	6,000	—	$0	6,000	SEC↗
RENTON HOLLINGS	Director	D To issuer deriv	2026-04-20	2026-04-22	6,000	—	$0	6,000	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2026-04-20	2026-04-22	6,000	—	$0	6,000	SEC↗
RENTON HOLLINGS	Director	D To issuer deriv	2026-04-20	2026-04-22	6,000	—	$0	6,000	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2026-04-20	2026-04-22	15,000	—	$0	15,000	SEC↗
RENTON HOLLINGS	Director	D To issuer deriv	2026-04-20	2026-04-22	15,000	—	$0	15,000	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2026-04-20	2026-04-22	5,500	—	$0	5,500	SEC↗
RENTON HOLLINGS	Director	D To issuer deriv	2026-04-20	2026-04-22	5,500	—	$0	5,500	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2026-04-20	2026-04-22	16,510	—	$0	16,510	SEC↗
RENTON HOLLINGS	Director	D To issuer deriv	2026-04-20	2026-04-22	16,510	—	$0	16,510	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2026-04-20	2026-04-22	16,510	—	$0	16,510	SEC↗
RENTON HOLLINGS	Director	D To issuer deriv	2026-04-20	2026-04-22	16,510	—	$0	16,510	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2026-04-20	2026-04-22	10,600	—	$0	10,600	SEC↗
RENTON HOLLINGS	Director	D To issuer deriv	2026-04-20	2026-04-22	9,200	—	$0	9,200	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2026-04-20	2026-04-22	9,200	—	$0	9,200	SEC↗
Schmid John P.	Director	A Award deriv	2026-04-20	2026-04-22	16,510	—	$0	16,510	SEC↗
Schmid John P.	Director	D To issuer deriv	2026-04-20	2026-04-22	16,510	—	$0	16,510	SEC↗
Schmid John P.	Director	A Award deriv	2026-04-20	2026-04-22	10,600	—	$0	10,600	SEC↗
Schmid John P.	Director	D To issuer deriv	2026-04-20	2026-04-22	10,600	—	$0	10,600	SEC↗
Schmid John P.	Director	A Award deriv	2026-04-20	2026-04-22	9,200	—	$0	9,200	SEC↗
Schmid John P.	Director	D To issuer deriv	2026-04-20	2026-04-22	9,200	—	$0	9,200	SEC↗
Schmid John P.	Director	A Award deriv	2026-04-20	2026-04-22	11,000	—	$0	11,000	SEC↗
Schmid John P.	Director	D To issuer deriv	2026-04-20	2026-04-22	11,000	—	$0	11,000	SEC↗
Schmid John P.	Director	A Award deriv	2026-04-20	2026-04-22	11,000	—	$0	11,000	SEC↗
Schmid John P.	Director	D To issuer deriv	2026-04-20	2026-04-22	11,000	—	$0	11,000	SEC↗
Schmid John P.	Director	A Award deriv	2026-04-20	2026-04-22	6,000	—	$0	6,000	SEC↗
Schmid John P.	Director	D To issuer deriv	2026-04-20	2026-04-22	6,000	—	$0	6,000	SEC↗
Schmid John P.	Director	A Award deriv	2026-04-20	2026-04-22	6,000	—	$0	6,000	SEC↗
Schmid John P.	Director	D To issuer deriv	2026-04-20	2026-04-22	6,000	—	$0	6,000	SEC↗
Schmid John P.	Director	A Award deriv	2026-04-20	2026-04-22	15,000	—	$0	15,000	SEC↗
Schmid John P.	Director	D To issuer deriv	2026-04-20	2026-04-22	15,000	—	$0	15,000	SEC↗
Schmid John P.	Director	A Award deriv	2026-04-20	2026-04-22	5,500	—	$0	5,500	SEC↗
Schmid John P.	Director	D To issuer deriv	2026-04-20	2026-04-22	5,500	—	$0	5,500	SEC↗
Schmid John P.	Director	A Award deriv	2026-04-20	2026-04-22	16,510	—	$0	16,510	SEC↗
Schmid John P.	Director	D To issuer deriv	2026-04-20	2026-04-22	16,510	—	$0	16,510	SEC↗
Orwin John A	Director	A Award deriv	2026-04-20	2026-04-22	8,250	—	$0	8,250	SEC↗
Orwin John A	Director	D To issuer deriv	2026-04-20	2026-04-22	16,510	—	$0	16,510	SEC↗
Orwin John A	Director	D To issuer deriv	2026-04-20	2026-04-22	3,311	—	$0	3,311	SEC↗
Orwin John A	Director	A Award deriv	2026-04-20	2026-04-22	3,311	—	$0	3,311	SEC↗
Orwin John A	Director	D To issuer deriv	2026-04-20	2026-04-22	10,600	—	$0	10,600	SEC↗
Orwin John A	Director	A Award deriv	2026-04-20	2026-04-22	10,600	—	$0	10,600	SEC↗
Orwin John A	Director	D To issuer deriv	2026-04-20	2026-04-22	8,250	—	$0	8,250	SEC↗
Orwin John A	Director	A Award deriv	2026-04-20	2026-04-22	16,510	—	$0	16,510	SEC↗
Orwin John A	Director	D To issuer deriv	2026-04-20	2026-04-22	16,510	—	$0	16,510	SEC↗
Orwin John A	Director	A Award deriv	2026-04-20	2026-04-22	16,510	—	$0	16,510	SEC↗
Faga Daniel	President, CEO	D To issuer deriv	2026-04-20	2026-04-23	11,000	—	$0	11,000	SEC↗
Schmid John P.	Director	S Sale	2026-03-30	2026-04-01	522	$57.40	$30.0K	31,622	SEC↗
Schmid John P.	Director	S Sale	2026-03-30	2026-04-01	7,527	$56.70	$426.8K	32,144	SEC↗
Schmid John P.	Director	S Sale	2026-03-30	2026-04-01	12,596	$55.71	$701.7K	39,671	SEC↗
Faga Daniel	President, CEO	S Sale	2026-03-27	2026-03-27	2,570	$57.91	$148.8K	510,564	SEC↗
Faga Daniel	President, CEO	S Sale	2026-03-27	2026-03-27	510	$56.61	$28.9K	513,134	SEC↗
Faga Daniel	President, CEO	S Sale	2026-03-27	2026-03-27	3,662	$58.62	$214.7K	506,902	SEC↗
Faga Daniel	President, CEO	S Sale	2026-03-27	2026-03-27	490	$59.62	$29.2K	506,412	SEC↗
Faga Daniel	President, CEO	S Sale	2026-03-27	2026-03-27	550	$60.63	$33.3K	505,862	SEC↗
Faga Daniel	President, CEO	S Sale	2026-03-27	2026-03-27	1,012	$62.15	$62.9K	504,850	SEC↗
Faga Daniel	President, CEO	S Sale	2026-03-27	2026-03-27	2,592	$63.35	$164.2K	502,258	SEC↗
Faga Daniel	President, CEO	S Sale	2026-03-27	2026-03-27	3,155	$64.19	$202.5K	499,103	SEC↗
Faga Daniel	President, CEO	S Sale	2026-03-27	2026-03-27	3,038	$65.20	$198.1K	496,065	SEC↗
Faga Daniel	President, CEO	S Sale	2026-03-27	2026-03-27	100	$65.99	$6.6K	495,965	SEC↗
Faga Daniel	President, CEO	A Award	2026-03-25	2026-03-27	34,300	—	$0	513,644	SEC↗
Faga Daniel	President, CEO	A Award deriv	2026-03-12	2026-08-07	53,334	—	$0	53,334	SEC↗
Lizzul Paul F.	Chief Medical Officer	A Award deriv	2026-03-12	2026-08-07	16,667	—	$0	16,667	SEC↗
Lizzul Paul F.	Chief Medical Officer	A Award deriv	2026-03-12	2026-08-07	16,667	—	$0	16,667	SEC↗
Faga Daniel	President, CEO, Director	A Award deriv	2026-03-12	2026-08-07	53,334	—	$0	53,334	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2026-02-11	2026-02-13	10,000	—	$0	35,000	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2026-02-11	2026-02-13	10,000	$54.00	$540.0K	12,835	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2026-02-11	2026-02-13	10,000	$29.70	$297.0K	22,835	SEC↗
Marquet Magda	Director	M Exercise deriv	2026-01-15	2026-01-16	11,000	—	$0	0	SEC↗
Marquet Magda	Director	M Exercise	2026-01-15	2026-01-16	11,000	$26.11	$287.2K	20,930	SEC↗
Marquet Magda	Director	S Sale	2026-01-15	2026-01-16	1,710	$48.85	$83.5K	9,930	SEC↗
Marquet Magda	Director	S Sale	2026-01-15	2026-01-16	9,290	$48.12	$447.0K	11,640	SEC↗
Faga Daniel	President, CEO	S Sale	2026-01-08	2026-01-09	14,281	$44.71	$638.5K	479,344	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2026-01-08	2026-01-09	2,210	$44.71	$98.8K	12,835	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	S Sale	2026-01-08	2026-01-09	2,515	$44.71	$112.4K	21,852	SEC↗
Lizzul Paul F.	Chief Medical Officer	S Sale	2026-01-08	2026-01-09	3,650	$44.71	$163.2K	42,088	SEC↗
Faga Daniel	President, CEO	M Exercise deriv	2026-01-07	2026-01-09	26,838	—	$0	80,512	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2026-01-07	2026-01-09	5,888	—	$0	17,662	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise deriv	2026-01-07	2026-01-09	6,700	—	$0	20,100	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise deriv	2026-01-07	2026-01-09	8,525	—	$0	25,575	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	S Sale	2026-01-07	2026-01-08	1,908	$45.11	$86.1K	17,667	SEC↗
Faga Daniel	President, CEO	S Sale	2026-01-07	2026-01-08	9,202	$45.11	$415.1K	466,787	SEC↗
Lizzul Paul F.	Chief Medical Officer	S Sale	2026-01-07	2026-01-08	2,235	$45.11	$100.8K	37,213	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2026-01-07	2026-01-08	1,841	$46.13	$84.9K	9,657	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2026-01-07	2026-01-08	500	$47.23	$23.6K	9,157	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2026-01-07	2026-01-08	5,281	$45.38	$239.7K	11,498	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2026-01-07	2026-01-08	2,017	$45.11	$91.0K	16,779	SEC↗
Faga Daniel	President, CEO	M Exercise	2026-01-07	2026-01-09	26,838	—	$0	493,625	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2026-01-07	2026-01-09	5,888	—	$0	15,045	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise	2026-01-07	2026-01-09	6,700	—	$0	24,367	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise	2026-01-07	2026-01-09	8,525	—	$0	45,738	SEC↗
Orwin John A	Director	A Award deriv	2026-01-06	2026-01-08	8,250	—	$0	8,250	SEC↗
Orwin John A	Director	A Award deriv	2026-01-06	2026-01-08	6,000	—	$0	6,000	SEC↗
Ware J. Anthony	Director	A Award deriv	2026-01-06	2026-01-08	4,000	—	$0	4,000	SEC↗
Ware J. Anthony	Director	A Award deriv	2026-01-06	2026-01-08	5,500	—	$0	5,500	SEC↗
Schmid John P.	Director	A Award deriv	2026-01-06	2026-01-08	5,500	—	$0	5,500	SEC↗
Schmid John P.	Director	A Award deriv	2026-01-06	2026-01-08	4,000	—	$0	4,000	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2026-01-06	2026-01-08	4,000	—	$0	4,000	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2026-01-06	2026-01-08	5,500	—	$0	5,500	SEC↗
Marquet Magda	Director	A Award deriv	2026-01-06	2026-01-08	4,000	—	$0	4,000	SEC↗
Marquet Magda	Director	A Award deriv	2026-01-06	2026-01-08	5,500	—	$0	5,500	SEC↗
Jain Rita	Director	A Award deriv	2026-01-06	2026-01-08	5,500	—	$0	5,500	SEC↗
Jain Rita	Director	A Award deriv	2026-01-06	2026-01-08	4,000	—	$0	4,000	SEC↗
FENTON DENNIS M	Director	A Award deriv	2026-01-06	2026-01-08	4,000	—	$0	4,000	SEC↗
FENTON DENNIS M	Director	A Award deriv	2026-01-06	2026-01-08	5,500	—	$0	5,500	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise deriv	2026-01-06	2026-01-08	5,245	—	$0	5,245	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	A Award deriv	2026-01-06	2026-01-08	21,400	—	$0	21,400	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	A Award deriv	2026-01-06	2026-01-08	29,000	—	$0	29,000	SEC↗
Faga Daniel	President, CEO	M Exercise deriv	2026-01-06	2026-01-08	17,850	—	$0	17,850	SEC↗
Faga Daniel	President, CEO	A Award deriv	2026-01-06	2026-01-08	133,400	—	$0	133,400	SEC↗
Faga Daniel	President, CEO	A Award deriv	2026-01-06	2026-01-08	98,600	—	$0	98,600	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise deriv	2026-01-06	2026-01-08	6,145	—	$0	6,145	SEC↗
Lizzul Paul F.	Chief Medical Officer	A Award deriv	2026-01-06	2026-01-08	21,400	—	$0	21,400	SEC↗
Lizzul Paul F.	Chief Medical Officer	A Award deriv	2026-01-06	2026-01-08	29,000	—	$0	29,000	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	A Award deriv	2026-01-06	2026-01-08	23,200	—	$0	23,200	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2026-01-06	2026-01-08	5,545	—	$0	5,545	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	A Award deriv	2026-01-06	2026-01-08	17,100	—	$0	17,100	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise	2026-01-06	2026-01-08	5,245	—	$0	19,575	SEC↗
Faga Daniel	President, CEO	M Exercise	2026-01-06	2026-01-08	17,850	—	$0	475,989	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise	2026-01-06	2026-01-08	6,145	—	$0	39,448	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2026-01-06	2026-01-08	5,545	—	$0	18,796	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2026-01-05	2026-01-06	2,983	$43.26	$129.0K	13,251	SEC↗
Lizzul Paul F.	Chief Medical Officer	S Sale	2026-01-05	2026-01-06	4,219	$43.26	$182.5K	33,303	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	S Sale	2026-01-05	2026-01-06	3,363	$43.26	$145.5K	14,330	SEC↗
Faga Daniel	President, CEO	S Sale	2026-01-05	2026-01-06	15,309	$43.26	$662.3K	458,139	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2026-01-03	2026-01-06	7,287	—	$0	14,575	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise deriv	2026-01-03	2026-01-06	10,555	—	$0	21,110	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise deriv	2026-01-03	2026-01-06	8,292	—	$0	16,585	SEC↗
Faga Daniel	President, CEO	M Exercise deriv	2026-01-03	2026-01-06	34,677	—	$0	69,355	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2026-01-03	2026-01-06	7,287	—	$0	16,234	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise	2026-01-03	2026-01-06	10,555	—	$0	37,522	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise	2026-01-03	2026-01-06	8,292	—	$0	17,693	SEC↗
Faga Daniel	President, CEO	M Exercise	2026-01-03	2026-01-06	34,677	—	$0	473,448	SEC↗
Schmid John P.	Director	J Other	2025-12-23	2025-12-23	11,068	$51.00	$564.5K	0	SEC↗
Ware J. Anthony	Director	S Sale	2025-12-23	2025-12-23	3,900	$49.58	$193.4K	9,630	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2025-12-22	2025-12-23	10,000	—	$0	43,000	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise deriv	2025-12-22	2025-12-23	10,000	—	$0	60,600	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise deriv	2025-12-22	2025-12-23	1,500	—	$0	83,500	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2025-12-22	2025-12-23	10,000	$14.02	$140.2K	18,947	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2025-12-22	2025-12-23	10,000	$51.00	$510.0K	8,947	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise	2025-12-22	2025-12-23	10,000	$20.16	$201.6K	19,401	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	S Sale	2025-12-22	2025-12-23	10,000	$50.00	$500.0K	9,401	SEC↗
Lizzul Paul F.	Chief Medical Officer	S Sale	2025-12-22	2025-12-23	1,500	$50.00	$75.0K	26,967	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise	2025-12-22	2025-12-23	1,500	$18.50	$27.8K	28,467	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2025-12-18	2025-12-18	141	$46.99	$6.6K	8,947	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2025-12-17	2025-12-18	10,000	—	$0	53,000	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2025-12-17	2025-12-18	10,000	$14.02	$140.2K	19,088	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2025-12-17	2025-12-18	10,000	$46.00	$460.0K	9,088	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise deriv	2025-12-16	2025-12-18	10,000	—	$0	70,600	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2025-12-16	2025-12-18	7,500	—	$0	0	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2025-12-16	2025-12-18	5,000	—	$0	63,000	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise	2025-12-16	2025-12-18	10,000	$20.16	$201.6K	25,126	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	S Sale	2025-12-16	2025-12-18	6,360	$45.21	$287.5K	9,401	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	S Sale	2025-12-16	2025-12-18	9,365	$44.62	$417.9K	15,761	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2025-12-16	2025-12-18	5,000	$14.02	$70.1K	14,088	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2025-12-16	2025-12-18	4,195	$45.24	$189.8K	9,088	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2025-12-16	2025-12-18	8,305	$44.68	$371.1K	13,283	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2025-12-16	2025-12-18	7,500	$20.16	$151.2K	21,588	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2025-09-30	2025-10-01	5,000	—	$0	68,000	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2025-09-30	2025-10-01	5,000	$14.02	$70.1K	17,328	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2025-09-30	2025-10-01	8,240	$29.00	$239.0K	9,088	SEC↗
Orwin John A	Director	M Exercise deriv	2025-09-15	2025-09-17	1,300	—	$0	1,300	SEC↗
Orwin John A	Director	M Exercise	2025-09-15	2025-09-17	1,300	—	$0	10,665	SEC↗
RENTON HOLLINGS	Director	M Exercise deriv	2025-08-08	2025-08-12	10,231	—	$0	0	SEC↗
RENTON HOLLINGS	Director	M Exercise	2025-08-08	2025-08-12	10,231	$6.93	$70.9K	15,196	SEC↗
RENTON HOLLINGS	Director	S Sale	2025-08-08	2025-08-12	7,121	$19.70	$140.3K	4,965	SEC↗
RENTON HOLLINGS	Director	S Sale	2025-08-08	2025-08-12	3,110	$19.44	$60.5K	12,086	SEC↗
RENTON HOLLINGS	Director	M Exercise deriv	2025-07-02	2025-07-03	20,925	—	$0	0	SEC↗
RENTON HOLLINGS	Director	S Sale	2025-07-02	2025-07-03	7,250	$23.09	$167.4K	18,640	SEC↗
RENTON HOLLINGS	Director	S Sale	2025-07-02	2025-07-03	13,675	$23.82	$325.7K	4,965	SEC↗
RENTON HOLLINGS	Director	M Exercise	2025-07-02	2025-07-03	20,925	$6.93	$145.0K	25,890	SEC↗
RENTON HOLLINGS	Director	S Sale	2025-06-18	2025-06-20	3,015	$23.97	$72.3K	4,965	SEC↗
FENTON DENNIS M	Director	S Sale	2025-06-18	2025-06-20	3,015	$23.97	$72.3K	4,965	SEC↗
Ware J. Anthony	Director	M Exercise deriv	2025-06-15	2025-06-17	6,030	—	$0	0	SEC↗
Schmid John P.	Director	M Exercise deriv	2025-06-15	2025-06-17	6,030	—	$0	0	SEC↗
RENTON HOLLINGS	Director	M Exercise deriv	2025-06-15	2025-06-17	6,030	—	$0	0	SEC↗
Orwin John A	Director	M Exercise deriv	2025-06-15	2025-06-17	6,030	—	$0	0	SEC↗
Marquet Magda	Director	M Exercise deriv	2025-06-15	2025-06-17	6,030	—	$0	0	SEC↗
FENTON DENNIS M	Director	M Exercise deriv	2025-06-15	2025-06-17	6,030	—	$0	0	SEC↗
Jain Rita	Director	M Exercise deriv	2025-06-15	2025-06-17	1,300	—	$0	1,300	SEC↗
Jain Rita	Director	M Exercise deriv	2025-06-15	2025-06-17	6,030	—	$0	0	SEC↗
Ware J. Anthony	Director	M Exercise	2025-06-15	2025-06-17	6,030	—	$0	13,530	SEC↗
Schmid John P.	Director	M Exercise	2025-06-15	2025-06-17	6,030	—	$0	52,267	SEC↗
RENTON HOLLINGS	Director	M Exercise	2025-06-15	2025-06-17	6,030	—	$0	7,980	SEC↗
Orwin John A	Director	M Exercise	2025-06-15	2025-06-17	6,030	—	$0	9,365	SEC↗
Marquet Magda	Director	M Exercise	2025-06-15	2025-06-17	6,030	—	$0	9,930	SEC↗
FENTON DENNIS M	Director	M Exercise	2025-06-15	2025-06-17	6,030	—	$0	7,980	SEC↗
Jain Rita	Director	M Exercise	2025-06-15	2025-06-17	7,330	—	$0	11,864	SEC↗
Schmid John P.	Director	J Other	2025-03-25	2025-03-27	11,068	$18.18	$201.2K	11,068	SEC↗
Schmid John P.	Director	M Exercise deriv	2025-01-13	2025-01-15	21,692	—	$0	0	SEC↗
Schmid John P.	Director	M Exercise deriv	2025-01-13	2025-01-15	20,645	—	$0	0	SEC↗
Schmid John P.	Director	M Exercise	2025-01-13	2025-01-15	21,692	$4.55	$98.7K	25,592	SEC↗
Schmid John P.	Director	M Exercise	2025-01-13	2025-01-15	20,645	$8.54	$176.3K	46,237	SEC↗
Faga Daniel	President, CEO	A Award deriv	2025-01-07	2025-01-07	305,500	—	$0	305,500	SEC↗
Faga Daniel	President, CEO	A Award deriv	2025-01-07	2025-01-07	107,350	—	$0	107,350	SEC↗
Ware J. Anthony	Director	A Award deriv	2025-01-07	2025-01-07	16,510	—	$0	16,510	SEC↗
Ware J. Anthony	Director	A Award deriv	2025-01-07	2025-01-07	6,030	—	$0	6,030	SEC↗
Schmid John P.	Director	A Award deriv	2025-01-07	2025-01-07	16,510	—	$0	16,510	SEC↗
Schmid John P.	Director	A Award deriv	2025-01-07	2025-01-07	6,030	—	$0	6,030	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2025-01-07	2025-01-07	6,030	—	$0	6,030	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2025-01-07	2025-01-07	16,510	—	$0	16,510	SEC↗
Orwin John A	Director	A Award deriv	2025-01-07	2025-01-07	6,030	—	$0	6,030	SEC↗
Orwin John A	Director	A Award deriv	2025-01-07	2025-01-07	16,510	—	$0	16,510	SEC↗
Marquet Magda	Director	A Award deriv	2025-01-07	2025-01-07	16,510	—	$0	16,510	SEC↗
Marquet Magda	Director	A Award deriv	2025-01-07	2025-01-07	6,030	—	$0	6,030	SEC↗
Jain Rita	Director	A Award deriv	2025-01-07	2025-01-07	6,030	—	$0	6,030	SEC↗
Jain Rita	Director	A Award deriv	2025-01-07	2025-01-07	16,510	—	$0	16,510	SEC↗
FENTON DENNIS M	Director	A Award deriv	2025-01-07	2025-01-07	16,510	—	$0	16,510	SEC↗
FENTON DENNIS M	Director	A Award deriv	2025-01-07	2025-01-07	6,030	—	$0	6,030	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	A Award deriv	2025-01-07	2025-01-07	23,550	—	$0	23,550	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	A Award deriv	2025-01-07	2025-01-07	67,000	—	$0	67,000	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	A Award deriv	2025-01-07	2025-01-07	26,800	—	$0	26,800	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	A Award deriv	2025-01-07	2025-01-07	76,400	—	$0	76,400	SEC↗
Lizzul Paul F.	Chief Medical Officer	A Award deriv	2025-01-07	2025-01-07	97,200	—	$0	97,200	SEC↗
Lizzul Paul F.	Chief Medical Officer	A Award deriv	2025-01-07	2025-01-07	34,100	—	$0	34,100	SEC↗
Faga Daniel	President, CEO	M Exercise deriv	2025-01-06	2025-01-07	17,850	—	$0	35,700	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2025-01-06	2025-01-07	5,545	—	$0	11,090	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise deriv	2025-01-06	2025-01-07	5,245	—	$0	10,490	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise deriv	2025-01-06	2025-01-07	6,145	—	$0	12,290	SEC↗
Faga Daniel	President, CEO	M Exercise	2025-01-06	2025-01-07	17,850	—	$0	442,853	SEC↗
Faga Daniel	President, CEO	F Tax w/h	2025-01-06	2025-01-07	6,387	$15.30	$97.7K	436,466	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2025-01-06	2025-01-07	5,545	—	$0	13,220	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	F Tax w/h	2025-01-06	2025-01-07	2,217	$15.30	$33.9K	11,003	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	F Tax w/h	2025-01-06	2025-01-07	2,054	$15.30	$31.4K	13,802	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise	2025-01-06	2025-01-07	5,245	—	$0	15,856	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise	2025-01-06	2025-01-07	6,145	—	$0	27,904	SEC↗
Lizzul Paul F.	Chief Medical Officer	F Tax w/h	2025-01-06	2025-01-07	2,261	$15.30	$34.6K	25,643	SEC↗
Faga Daniel	President, CEO	M Exercise deriv	2025-01-03	2025-01-07	34,678	—	$0	104,032	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2025-01-03	2025-01-07	7,288	—	$0	21,862	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise deriv	2025-01-03	2025-01-07	8,293	—	$0	24,877	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise deriv	2025-01-03	2025-01-07	10,555	—	$0	31,665	SEC↗
Faga Daniel	President, CEO	M Exercise	2025-01-03	2025-01-07	34,678	—	$0	438,036	SEC↗
Faga Daniel	President, CEO	F Tax w/h	2025-01-03	2025-01-07	13,033	$14.60	$190.3K	425,003	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2025-01-03	2025-01-07	7,288	—	$0	10,669	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	F Tax w/h	2025-01-03	2025-01-07	2,994	$14.60	$43.7K	7,675	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise	2025-01-03	2025-01-07	8,293	—	$0	14,018	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	F Tax w/h	2025-01-03	2025-01-07	3,407	$14.60	$49.7K	10,611	SEC↗
Lizzul Paul F.	Chief Medical Officer	F Tax w/h	2025-01-03	2025-01-07	4,336	$14.60	$63.3K	21,759	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise	2025-01-03	2025-01-07	10,555	—	$0	26,095	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-01-02	2025-01-02	6,646	$12.95	$86.1K	7,880,094	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2024-12-31	2025-01-02	13,268	$12.93	$171.6K	7,873,448	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2024-12-30	2025-01-02	65,184	$12.92	$842.2K	7,860,180	SEC↗
RENTON HOLLINGS	Director	M Exercise deriv	2024-11-29	2024-12-03	10,000	—	$0	20,925	SEC↗
RENTON HOLLINGS	Director	S Sale	2024-11-29	2024-12-03	10,000	$25.00	$250.0K	1,950	SEC↗
RENTON HOLLINGS	Director	M Exercise	2024-11-29	2024-12-03	10,000	$6.93	$69.3K	11,950	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise deriv	2024-09-23	2024-09-24	1,500	—	$0	85,000	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise	2024-09-23	2024-09-24	1,500	$18.50	$27.8K	16,898	SEC↗
Lizzul Paul F.	Chief Medical Officer	S Sale	2024-09-23	2024-09-24	1,500	$38.67	$58.0K	15,398	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2024-09-17	2024-09-17	3,780	$38.41	$145.2K	3,240	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise deriv	2024-09-16	2024-09-17	10,000	—	$0	80,600	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2024-09-16	2024-09-17	5,000	—	$0	73,000	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	S Sale	2024-09-16	2024-09-17	2,220	$38.93	$86.4K	4,744	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise	2024-09-16	2024-09-17	10,000	$20.16	$201.6K	14,744	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	S Sale	2024-09-16	2024-09-17	10,000	$40.13	$401.3K	4,744	SEC↗
Lizzul Paul F.	Chief Medical Officer	S Sale	2024-09-16	2024-09-17	2,220	$38.93	$86.4K	15,398	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2024-09-16	2024-09-17	6,500	$40.13	$260.8K	7,020	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	S Sale	2024-09-16	2024-09-17	2,220	$38.93	$86.4K	8,520	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2024-09-16	2024-09-17	5,000	$14.02	$70.1K	13,520	SEC↗
Orwin John A	Director	M Exercise deriv	2024-09-15	2024-09-17	1,300	—	$0	2,600	SEC↗
Orwin John A	Director	M Exercise	2024-09-15	2024-09-17	1,300	—	$0	3,335	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise deriv	2024-09-14	2024-09-17	6,000	—	$0	0	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise deriv	2024-09-14	2024-09-17	6,000	—	$0	0	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise deriv	2024-09-14	2024-09-17	6,000	—	$0	0	SEC↗
MULROY DENNIS	CHIEF FINANCIAL OFFICER	M Exercise	2024-09-14	2024-09-17	6,000	—	$0	6,964	SEC↗
Lizzul Paul F.	Chief Medical Officer	M Exercise	2024-09-14	2024-09-17	6,000	—	$0	17,618	SEC↗
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	M Exercise	2024-09-14	2024-09-17	6,000	—	$0	10,740	SEC↗