APLT

Applied Therapeutics, Inc.CIK 1697532 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for APLT PRO

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AI insights for APLT

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Bailey Evan Prescott	Chief Medical Officer	6	$0	$0	2026-02-03
Chinoporos Constantine	See Remarks	7	$0	$17.3K	2026-02-03
Kanter Stacy J.	Director	26	$509.7K	$4.7K	2026-02-03
Lerner Teena	Director	29	$0	$0	2026-02-03
Funtleyder Leslie D.	See Remarks	85	$0	$5.27M	2026-02-03
Hooks Corwin Dale	Chief Commercial Officer	5	$0	$0	2026-02-03
SKYLER JAY S	Director	22	$0	$0	2026-02-03
Perfetti Riccardo	Chief Medical Officer	210	$125.8K	$3.22M	2025-03-04
JOHNSON JOHN	Executive Chairman	2	$0	$0	2024-12-19
Shendelman Shoshana	President and CEO	76	$1.49M	$15.00M	2024-08-14
MARCUS JOEL S	Director	50	$1.52M	$1.78M	2024-06-06
Alexandria Equities No. 7, LLC	10% Owner	10	$9.75M	$2.05M	2024-06-05
Hansard Adam	Chief Commercial Officer	26	$0	$348.8K	2024-03-14
ALEXANDRIA REAL ESTATE EQUITIES, INC.	10% Owner	7	$1000.0K	$572.2K	2023-11-03
Alexandria Venture Investments, LLC	10% Owner	12	$5.00M	$0	2023-10-12
Ortega Steven A.	Principal Accounting Officer	3	$0	$0	2022-11-15
Mahadevan Chids	See Remarks	11	$0	$1.5K	2022-08-02
Silberstein Charles	Chief Financial Officer	9	$0	$108.1K	2022-01-07
Vignola Mark J.	Chief Financial Officer	1	$0	$0	2019-05-13

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Lerner Teena	Director	D To issuer deriv	2026-02-03	2026-02-03	16,500	—	$0	0	SEC↗
Lerner Teena	Director	D To issuer deriv	2026-02-03	2026-02-03	16,500	—	$0	0	SEC↗
Lerner Teena	Director	D To issuer deriv	2026-02-03	2026-02-03	10,230	—	$0	0	SEC↗
Lerner Teena	Director	D To issuer deriv	2026-02-03	2026-02-03	20,460	—	$0	0	SEC↗
Lerner Teena	Director	D To issuer deriv	2026-02-03	2026-02-03	23,941	—	$0	0	SEC↗
Lerner Teena	Director	D To issuer deriv	2026-02-03	2026-02-03	200,000	—	$0	0	SEC↗
Bailey Evan Prescott	Chief Medical Officer	D To issuer deriv	2026-02-03	2026-02-03	4,883	—	$0	0	SEC↗
Bailey Evan Prescott	Chief Medical Officer	D To issuer deriv	2026-02-03	2026-02-03	19,531	—	$0	0	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	D To issuer deriv	2026-02-03	2026-02-03	20,460	—	$0	0	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	D To issuer deriv	2026-02-03	2026-02-03	16,500	—	$0	0	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	D To issuer deriv	2026-02-03	2026-02-03	16,500	—	$0	0	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	D To issuer deriv	2026-02-03	2026-02-03	150,000	—	$0	0	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	D To issuer deriv	2026-02-03	2026-02-03	40,502	—	$0	0	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	D To issuer deriv	2026-02-03	2026-02-03	10,230	—	$0	0	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2026-02-03	2026-02-03	16,500	—	$0	0	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2026-02-03	2026-02-03	16,500	—	$0	0	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2026-02-03	2026-02-03	20,460	—	$0	0	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2026-02-03	2026-02-03	200,000	—	$0	0	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2026-02-03	2026-02-03	10,230	—	$0	0	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2026-02-03	2026-02-04	16,500	—	$0	0	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2026-02-03	2026-02-04	16,500	—	$0	0	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2026-02-03	2026-02-04	20,460	—	$0	0	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2026-02-03	2026-02-04	200,000	—	$0	0	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2026-02-03	2026-02-04	10,230	—	$0	0	SEC↗
Lerner Teena	Director	U Tender	2026-02-03	2026-02-03	82,922	—	$0	0	SEC↗
Lerner Teena	Director	D To issuer	2026-02-03	2026-02-03	22,500	—	$0	82,922	SEC↗
Bailey Evan Prescott	Chief Medical Officer	D To issuer	2026-02-03	2026-02-03	1,235,915	—	$0	60,901	SEC↗
Bailey Evan Prescott	Chief Medical Officer	U Tender	2026-02-03	2026-02-03	60,901	—	$0	0	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	U Tender	2026-02-03	2026-02-03	152,959	—	$0	0	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	D To issuer	2026-02-03	2026-02-03	2,375,000	—	$0	152,959	SEC↗
SKYLER JAY S	Director	U Tender	2026-02-03	2026-02-03	42,500	—	$0	0	SEC↗
SKYLER JAY S	Director	D To issuer	2026-02-03	2026-02-03	22,500	—	$0	42,500	SEC↗
Chinoporos Constantine	See Remarks	D To issuer	2026-02-03	2026-02-03	1,000,000	—	$0	57,111	SEC↗
Chinoporos Constantine	See Remarks	U Tender	2026-02-03	2026-02-03	57,111	—	$0	0	SEC↗
Hooks Corwin Dale	Chief Commercial Officer	U Tender	2026-02-03	2026-02-03	5,753	—	$0	0	SEC↗
Hooks Corwin Dale	Chief Commercial Officer	D To issuer	2026-02-03	2026-02-03	862,500	—	$0	5,753	SEC↗
Kanter Stacy J.	Director	D To issuer	2026-02-03	2026-02-04	22,500	—	$0	42,500	SEC↗
Kanter Stacy J.	Director	U Tender	2026-02-03	2026-02-04	42,500	—	$0	0	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	A Award	2026-01-01	2026-01-02	150,000	—	$0	1,340,459	SEC↗
Bailey Evan Prescott	Chief Medical Officer	A Award	2025-12-19	2026-02-03	437,500	—	$0	1,296,816	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	A Award	2025-12-19	2026-02-03	1,187,500	—	$0	2,527,959	SEC↗
Chinoporos Constantine	See Remarks	A Award	2025-12-19	2026-02-03	437,500	—	$0	1,057,111	SEC↗
Hooks Corwin Dale	Chief Commercial Officer	A Award	2025-12-19	2026-02-03	312,500	—	$0	868,253	SEC↗
Kanter Stacy J.	Director	S Sale	2025-12-16	2025-12-18	43,000	$0.11	$4.7K	65,000	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	A Award	2025-10-01	2025-10-01	150,000	—	$0	1,190,459	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	A Award	2025-07-01	2025-07-03	150,000	—	$0	937,121	SEC↗
Bailey Evan Prescott	Chief Medical Officer	A Award	2025-06-15	2025-06-17	300,000	—	$0	841,669	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	A Award	2025-06-09	2025-07-03	150,000	—	$0	787,121	SEC↗
SKYLER JAY S	Director	A Award deriv	2025-06-09	2025-06-11	200,000	—	$0	200,000	SEC↗
Kanter Stacy J.	Director	A Award deriv	2025-06-09	2025-06-11	200,000	—	$0	200,000	SEC↗
Lerner Teena	Director	A Award deriv	2025-06-09	2025-06-11	200,000	—	$0	200,000	SEC↗
Chinoporos Constantine	See Remarks	A Award	2025-03-24	2025-03-26	350,000	—	$0	621,436	SEC↗
Funtleyder Leslie D.	See Remarks	A Award	2025-03-24	2025-03-26	350,000	—	$0	740,459	SEC↗
Hooks Corwin Dale	Chief Commercial Officer	A Award	2025-03-24	2025-03-26	250,000	—	$0	550,000	SEC↗
Chinoporos Constantine	See Remarks	S Sale	2025-03-04	2025-03-06	447	$0.44	$197	271,436	SEC↗
Funtleyder Leslie D.	See Remarks	S Sale	2025-03-04	2025-03-06	14,502	$0.44	$6.4K	390,459	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2025-03-04	2025-03-06	10,366	$0.44	$4.6K	890,409	SEC↗
Chinoporos Constantine	See Remarks	S Sale	2025-02-06	2025-02-07	28,117	$0.61	$17.2K	271,883	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2025-02-06	2025-02-07	86,078	$0.61	$52.5K	900,775	SEC↗
Funtleyder Leslie D.	See Remarks	S Sale	2025-02-06	2025-02-07	22,950	$0.61	$14.0K	404,961	SEC↗
Funtleyder Leslie D.	See Remarks	A Award deriv	2024-12-19	2024-12-20	150,000	—	$0	150,000	SEC↗
JOHNSON JOHN	Executive Chairman	A Award deriv	2024-12-19	2024-12-20	1,000,000	—	$0	1,000,000	SEC↗
Funtleyder Leslie D.	See Remarks	A Award	2024-12-19	2024-12-20	150,000	—	$0	427,911	SEC↗
JOHNSON JOHN	Executive Chairman	A Award	2024-12-19	2024-12-20	500,000	—	$0	500,000	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2024-08-22	2024-08-23	22,681	$5.83	$132.2K	986,853	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	S Sale	2024-08-22	2024-08-23	13,530	$5.83	$78.9K	277,911	SEC↗
Shendelman Shoshana	President and CEO	S Sale	2024-08-14	2024-08-14	119,591	$5.93	$709.2K	4,690,839	SEC↗
Shendelman Shoshana	President and CEO	S Sale	2024-08-13	2024-08-14	357,423	$6.18	$2.21M	4,810,430	SEC↗
Shendelman Shoshana	President and CEO	S Sale	2024-08-12	2024-08-14	300,000	$5.98	$1.79M	5,167,853	SEC↗
Shendelman Shoshana	President and CEO	G Gift	2024-08-05	2024-08-14	747,886	—	$0	747,886	SEC↗
Shendelman Shoshana	President and CEO	G Gift	2024-08-05	2024-08-14	747,886	—	$0	0	SEC↗
Lerner Teena	Director	A Award	2024-06-06	2024-06-07	45,000	—	$0	105,422	SEC↗
MARCUS JOEL S	Director	A Award	2024-06-06	2024-06-07	45,000	—	$0	498,414	SEC↗
SKYLER JAY S	Director	A Award	2024-06-06	2024-06-07	45,000	—	$0	65,000	SEC↗
Kanter Stacy J.	Director	A Award	2024-06-06	2024-06-07	45,000	—	$0	108,000	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	S Sale	2024-06-06	2024-06-10	16,980	$4.32	$73.4K	291,441	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2024-06-06	2024-06-10	22,003	$4.32	$95.1K	1,009,534	SEC↗
Shendelman Shoshana	President and CEO	S Sale	2024-06-06	2024-06-10	61,795	$4.32	$267.0K	3,756,019	SEC↗
Alexandria Equities No. 7, LLC	10% Owner	S Sale	2024-06-05	2024-06-06	150,000	$4.24	$636.0K	5,855,077	SEC↗
Alexandria Equities No. 7, LLC	10% Owner	S Sale	2024-06-04	2024-06-06	150,000	$4.21	$631.5K	6,005,077	SEC↗
Hooks Corwin Dale	Chief Commercial Officer	A Award	2024-04-12	2024-04-15	300,000	—	$0	300,000	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	S Sale	2024-03-14	2024-03-18	28,727	$5.39	$154.8K	308,421	SEC↗
Hansard Adam	Chief Commercial Officer	S Sale	2024-03-14	2024-03-18	48,871	$5.39	$263.4K	732,919	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2024-03-14	2024-03-18	110,804	$5.39	$597.2K	1,031,537	SEC↗
Shendelman Shoshana	President and CEO	S Sale	2024-03-14	2024-03-18	318,573	$5.39	$1.72M	3,817,814	SEC↗
Chinoporos Constantine	See Remarks	A Award	2023-12-28	2024-03-18	300,000	—	$0	300,000	SEC↗
Hansard Adam	Chief Commercial Officer	A Award	2023-12-21	2023-12-22	400,000	—	$0	781,790	SEC↗
Perfetti Riccardo	Chief Medical Officer	A Award	2023-12-21	2023-12-22	450,000	—	$0	1,142,341	SEC↗
Shendelman Shoshana	President and CEO	A Award	2023-12-21	2023-12-22	1,100,000	—	$0	3,696,387	SEC↗
Shendelman Shoshana	President and CEO	A Award	2023-12-21	2023-12-22	440,000	—	$0	4,136,387	SEC↗
Kanter Stacy J.	Director	P Buy	2023-12-01	2023-12-05	30,000	$2.18	$65.4K	63,000	SEC↗
Hansard Adam	Chief Commercial Officer	S Sale	2023-11-30	2023-12-01	965	$1.97	$1.9K	381,790	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2023-11-30	2023-12-01	1,583	$1.97	$3.1K	692,341	SEC↗
Shendelman Shoshana	President and CEO	S Sale	2023-11-30	2023-12-01	3,968	$1.97	$7.8K	2,596,387	SEC↗
Alexandria Equities No. 7, LLC	10% Owner	J Other	2023-11-29	2023-12-01	575,000	—	$0	203,977	SEC↗
Alexandria Equities No. 7, LLC	10% Owner	J Other	2023-11-29	2023-12-01	575,000	—	$0	6,155,077	SEC↗
Funtleyder Leslie D.	Chief Financial Officer	A Award	2023-11-20	2023-11-20	300,000	—	$0	337,148	SEC↗
ALEXANDRIA REAL ESTATE EQUITIE	10% Owner	S Sale	2023-11-03	2023-11-06	143,450	$2.31	$331.4K	5,580,077	SEC↗
ALEXANDRIA REAL ESTATE EQUITIE	10% Owner	S Sale	2023-11-02	2023-11-06	103,808	$2.32	$240.8K	5,723,527	SEC↗
Alexandria Equities No. 7, LLC	10% Owner	S Sale	2023-11-01	2023-11-02	172,742	$2.36	$407.7K	5,827,335	SEC↗
Alexandria Equities No. 7, LLC	10% Owner	S Sale	2023-10-31	2023-11-02	155,000	$2.41	$373.6K	6,000,077	SEC↗
Alexandria Venture Investments	10% Owner	J Other deriv	2023-10-12	2023-10-16	615,000	—	$0	1,500,000	SEC↗
Alexandria Venture Investments	10% Owner	J Other deriv	2023-10-12	2023-10-16	615,000	—	$0	0	SEC↗
Alexandria Venture Investments	10% Owner	J Other	2023-10-12	2023-10-16	1,600,000	—	$0	778,977	SEC↗
Alexandria Venture Investments	10% Owner	J Other	2023-10-12	2023-10-16	1,600,000	—	$0	6,155,077	SEC↗
Hansard Adam	Chief Commercial Officer	S Sale	2023-09-27	2023-09-29	9,720	$2.70	$26.2K	382,755	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2023-09-27	2023-09-29	10,932	$2.70	$29.5K	693,924	SEC↗
Shendelman Shoshana	President and CEO	S Sale	2023-09-27	2023-09-29	115,632	$2.70	$312.2K	2,600,355	SEC↗
MARCUS JOEL S	Director	M Exercise deriv	2023-09-15	2023-09-19	12,375	—	$0	0	SEC↗
MARCUS JOEL S	Director	M Exercise	2023-09-15	2023-09-19	12,375	$1.05	$13.0K	453,414	SEC↗
Funtleyder Leslie D.	Director	A Award	2023-06-06	2023-06-08	20,000	—	$0	37,148	SEC↗
Kanter Stacy J.	Director	A Award	2023-06-06	2023-06-08	20,000	—	$0	33,000	SEC↗
Lerner Teena	Director	A Award	2023-06-06	2023-06-08	20,000	—	$0	60,422	SEC↗
MARCUS JOEL S	Director	A Award	2023-06-06	2023-06-08	20,000	—	$0	441,039	SEC↗
SKYLER JAY S	Director	A Award	2023-06-06	2023-06-08	20,000	—	$0	20,000	SEC↗
Hansard Adam	Chief Commercial Officer	S Sale	2023-01-11	2023-01-13	4,495	$0.91	$4.1K	92,475	SEC↗
Hansard Adam	Chief Commercial Officer	A Award	2023-01-11	2023-01-13	300,000	—	$0	392,475	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2023-01-11	2023-01-13	6,053	$0.91	$5.5K	154,856	SEC↗
Perfetti Riccardo	Chief Medical Officer	A Award	2023-01-11	2023-01-13	550,000	—	$0	704,856	SEC↗
Shendelman Shoshana	President and CEO	S Sale	2023-01-11	2023-01-13	15,870	$0.91	$14.4K	751,625	SEC↗
Shendelman Shoshana	President and CEO	A Award	2023-01-11	2023-01-13	1,964,362	—	$0	2,715,987	SEC↗
Ortega Steven A.	Principal Accounting Officer	A Award	2022-11-15	2022-11-17	40,000	—	$0	55,404	SEC↗
Shendelman Shoshana	President and CEO	P Buy	2022-10-14	2022-10-14	50,000	$0.65	$32.5K	767,495	SEC↗
Shendelman Shoshana	President and CEO	P Buy	2022-10-13	2022-10-13	73,256	$0.56	$41.0K	717,495	SEC↗
Shendelman Shoshana	President and CEO	P Buy	2022-10-12	2022-10-12	38,153	$0.52	$19.8K	644,239	SEC↗
MARCUS JOEL S	Director	M Exercise deriv	2022-09-14	2022-09-16	4,125	—	$0	12,375	SEC↗
MARCUS JOEL S	Director	M Exercise deriv	2022-09-14	2022-09-16	16,500	—	$0	0	SEC↗
MARCUS JOEL S	Director	M Exercise deriv	2022-09-14	2022-09-16	10,230	—	$0	0	SEC↗
MARCUS JOEL S	Director	M Exercise deriv	2022-09-14	2022-09-16	7,389	—	$0	0	SEC↗
MARCUS JOEL S	Director	M Exercise	2022-09-14	2022-09-16	10,230	$1.05	$10.7K	400,414	SEC↗
MARCUS JOEL S	Director	M Exercise	2022-09-14	2022-09-16	7,389	$1.05	$7.8K	390,184	SEC↗
MARCUS JOEL S	Director	M Exercise	2022-09-14	2022-09-16	16,500	$1.05	$17.3K	416,914	SEC↗
MARCUS JOEL S	Director	M Exercise	2022-09-14	2022-09-16	4,125	$1.05	$4.3K	421,039	SEC↗
Funtleyder Leslie D.	Director	D To issuer deriv	2022-08-02	2022-08-04	20,460	—	$0	0	SEC↗
Funtleyder Leslie D.	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	0	SEC↗
Funtleyder Leslie D.	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	16,500	SEC↗
Funtleyder Leslie D.	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	0	SEC↗
Funtleyder Leslie D.	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	16,500	SEC↗
Funtleyder Leslie D.	Director	D To issuer deriv	2022-08-02	2022-08-04	10,230	—	$0	0	SEC↗
Funtleyder Leslie D.	Director	D To issuer deriv	2022-08-02	2022-08-04	10,230	—	$0	10,230	SEC↗
Funtleyder Leslie D.	Director	D To issuer deriv	2022-08-02	2022-08-04	20,460	—	$0	20,460	SEC↗
Hansard Adam	Chief Commercial Officer	D To issuer deriv	2022-08-02	2022-08-04	21,100	—	$0	21,100	SEC↗
Hansard Adam	Chief Commercial Officer	D To issuer deriv	2022-08-02	2022-08-04	104,665	—	$0	104,665	SEC↗
Hansard Adam	Chief Commercial Officer	D To issuer deriv	2022-08-02	2022-08-04	104,665	—	$0	0	SEC↗
Hansard Adam	Chief Commercial Officer	D To issuer deriv	2022-08-02	2022-08-04	21,100	—	$0	21,100	SEC↗
Hansard Adam	Chief Commercial Officer	D To issuer deriv	2022-08-02	2022-08-04	21,100	—	$0	0	SEC↗
Hansard Adam	Chief Commercial Officer	D To issuer deriv	2022-08-02	2022-08-04	32,339	—	$0	32,339	SEC↗
Hansard Adam	Chief Commercial Officer	D To issuer deriv	2022-08-02	2022-08-04	21,100	—	$0	0	SEC↗
Hansard Adam	Chief Commercial Officer	D To issuer deriv	2022-08-02	2022-08-04	50,000	—	$0	50,000	SEC↗
Hansard Adam	Chief Commercial Officer	D To issuer deriv	2022-08-02	2022-08-04	32,339	—	$0	0	SEC↗
Hansard Adam	Chief Commercial Officer	D To issuer deriv	2022-08-02	2022-08-04	50,000	—	$0	0	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	0	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2022-08-02	2022-08-04	20,460	—	$0	20,460	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2022-08-02	2022-08-04	20,460	—	$0	0	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2022-08-02	2022-08-04	10,230	—	$0	10,230	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2022-08-02	2022-08-04	10,230	—	$0	0	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	16,500	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	0	SEC↗
Kanter Stacy J.	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	16,500	SEC↗
Lerner Teena	Director	D To issuer deriv	2022-08-02	2022-08-04	20,460	—	$0	20,460	SEC↗
Lerner Teena	Director	D To issuer deriv	2022-08-02	2022-08-04	20,460	—	$0	0	SEC↗
Lerner Teena	Director	D To issuer deriv	2022-08-02	2022-08-04	10,230	—	$0	10,230	SEC↗
Lerner Teena	Director	D To issuer deriv	2022-08-02	2022-08-04	10,230	—	$0	0	SEC↗
Lerner Teena	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	16,500	SEC↗
Lerner Teena	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	0	SEC↗
Lerner Teena	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	16,500	SEC↗
Lerner Teena	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	0	SEC↗
Mahadevan Chids	See Remarks	D To issuer deriv	2022-08-02	2022-08-04	19,058	—	$0	19,058	SEC↗
Mahadevan Chids	See Remarks	D To issuer deriv	2022-08-02	2022-08-04	19,058	—	$0	0	SEC↗
Mahadevan Chids	See Remarks	D To issuer deriv	2022-08-02	2022-08-04	7,264	—	$0	0	SEC↗
Mahadevan Chids	See Remarks	D To issuer deriv	2022-08-02	2022-08-04	7,264	—	$0	7,264	SEC↗
Mahadevan Chids	See Remarks	D To issuer deriv	2022-08-02	2022-08-04	8,824	—	$0	0	SEC↗
Mahadevan Chids	See Remarks	D To issuer deriv	2022-08-02	2022-08-04	8,824	—	$0	8,824	SEC↗
MARCUS JOEL S	Director	D To issuer deriv	2022-08-02	2022-08-04	10,230	—	$0	10,230	SEC↗
MARCUS JOEL S	Director	D To issuer deriv	2022-08-02	2022-08-04	7,389	—	$0	0	SEC↗
MARCUS JOEL S	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	16,500	SEC↗
MARCUS JOEL S	Director	D To issuer deriv	2022-08-02	2022-08-04	10,230	—	$0	0	SEC↗
MARCUS JOEL S	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	16,500	SEC↗
MARCUS JOEL S	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	0	SEC↗
MARCUS JOEL S	Director	D To issuer deriv	2022-08-02	2022-08-04	7,389	—	$0	7,389	SEC↗
MARCUS JOEL S	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	D To issuer deriv	2022-08-02	2022-08-04	36,495	—	$0	36,495	SEC↗
Perfetti Riccardo	Chief Medical Officer	D To issuer deriv	2022-08-02	2022-08-04	32,100	—	$0	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	D To issuer deriv	2022-08-02	2022-08-04	32,100	—	$0	32,100	SEC↗
Perfetti Riccardo	Chief Medical Officer	D To issuer deriv	2022-08-02	2022-08-04	32,100	—	$0	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	D To issuer deriv	2022-08-02	2022-08-04	50,000	—	$0	50,000	SEC↗
Perfetti Riccardo	Chief Medical Officer	D To issuer deriv	2022-08-02	2022-08-04	36,495	—	$0	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	D To issuer deriv	2022-08-02	2022-08-04	32,100	—	$0	32,100	SEC↗
Perfetti Riccardo	Chief Medical Officer	D To issuer deriv	2022-08-02	2022-08-04	51,666	—	$0	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	D To issuer deriv	2022-08-02	2022-08-04	51,666	—	$0	51,666	SEC↗
Perfetti Riccardo	Chief Medical Officer	D To issuer deriv	2022-08-02	2022-08-04	134,997	—	$0	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	D To issuer deriv	2022-08-02	2022-08-04	134,997	—	$0	134,997	SEC↗
Perfetti Riccardo	Chief Medical Officer	D To issuer deriv	2022-08-02	2022-08-04	50,000	—	$0	0	SEC↗
Shendelman Shoshana	President and CEO	D To issuer deriv	2022-08-02	2022-08-04	607,484	—	$0	607,484	SEC↗
Shendelman Shoshana	President and CEO	D To issuer deriv	2022-08-02	2022-08-04	607,484	—	$0	0	SEC↗
Shendelman Shoshana	President and CEO	D To issuer deriv	2022-08-02	2022-08-04	23,317	—	$0	23,317	SEC↗
Shendelman Shoshana	President and CEO	D To issuer deriv	2022-08-02	2022-08-04	23,317	—	$0	0	SEC↗
Shendelman Shoshana	President and CEO	D To issuer deriv	2022-08-02	2022-08-04	134,979	—	$0	134,979	SEC↗
Shendelman Shoshana	President and CEO	D To issuer deriv	2022-08-02	2022-08-04	134,979	—	$0	0	SEC↗
Shendelman Shoshana	President and CEO	D To issuer deriv	2022-08-02	2022-08-04	101,670	—	$0	101,670	SEC↗
Shendelman Shoshana	President and CEO	D To issuer deriv	2022-08-02	2022-08-04	101,670	—	$0	0	SEC↗
Shendelman Shoshana	President and CEO	D To issuer deriv	2022-08-02	2022-08-04	234,616	—	$0	234,616	SEC↗
Shendelman Shoshana	President and CEO	D To issuer deriv	2022-08-02	2022-08-04	234,616	—	$0	0	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2022-08-02	2022-08-04	10,230	—	$0	0	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	0	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	16,500	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2022-08-02	2022-08-04	20,460	—	$0	20,460	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2022-08-02	2022-08-04	20,460	—	$0	0	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2022-08-02	2022-08-04	10,230	—	$0	10,230	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	16,500	SEC↗
SKYLER JAY S	Director	D To issuer deriv	2022-08-02	2022-08-04	16,500	—	$0	0	SEC↗
Alexandria Venture Investments	10% Owner	P Buy deriv	2022-06-27	2022-06-29	2,950,000	—	$0	2,950,000	SEC↗
Alexandria Venture Investments	10% Owner	P Buy deriv	2022-06-27	2022-06-29	2,050,000	—	$0	2,050,000	SEC↗
Alexandria Venture Investments	10% Owner	P Buy deriv	2022-06-27	2022-06-29	615,000	$1.00	$615.0K	615,000	SEC↗
Alexandria Venture Investments	10% Owner	P Buy deriv	2022-06-27	2022-06-29	885,000	$1.00	$885.0K	885,000	SEC↗
Alexandria Venture Investments	10% Owner	P Buy	2022-06-27	2022-06-29	1,435,000	$1.00	$1.44M	2,378,977	SEC↗
Alexandria Venture Investments	10% Owner	P Buy	2022-06-27	2022-06-29	2,065,000	$1.00	$2.06M	4,555,077	SEC↗
Funtleyder Leslie D.	Director	A Award deriv	2022-06-03	2022-06-07	16,500	—	$0	16,500	SEC↗
Kanter Stacy J.	Director	A Award deriv	2022-06-03	2022-06-07	16,500	—	$0	16,500	SEC↗
Lerner Teena	Director	A Award deriv	2022-06-03	2022-06-07	16,500	—	$0	16,500	SEC↗
MARCUS JOEL S	Director	A Award deriv	2022-06-03	2022-06-07	16,500	—	$0	16,500	SEC↗
SKYLER JAY S	Director	A Award deriv	2022-06-03	2022-06-07	16,500	—	$0	16,500	SEC↗
Mahadevan Chids	See Remarks	S Sale	2022-05-16	2022-05-18	905	$1.65	$1.5K	9,800	SEC↗
Hansard Adam	Chief Commercial Officer	A Award deriv	2022-04-13	2022-04-15	50,000	—	$0	50,000	SEC↗
Mahadevan Chids	See Remarks	A Award deriv	2022-04-13	2022-04-15	19,058	—	$0	19,058	SEC↗
Ortega Steven A.	Principal Accounting Officer	A Award deriv	2022-04-13	2022-04-15	10,675	—	$0	10,675	SEC↗
Perfetti Riccardo	Chief Medical Officer	A Award deriv	2022-04-13	2022-04-15	50,000	—	$0	50,000	SEC↗
Mahadevan Chids	See Remarks	A Award	2022-04-13	2022-04-15	2,136	—	$0	10,705	SEC↗
Ortega Steven A.	Principal Accounting Officer	A Award	2022-04-13	2022-04-15	3,081	—	$0	15,404	SEC↗
Perfetti Riccardo	Chief Medical Officer	P Buy	2022-03-23	2022-03-23	30,000	$1.97	$59.1K	160,909	SEC↗
Perfetti Riccardo	Chief Medical Officer	P Buy	2022-03-22	2022-03-23	21,961	$1.98	$43.5K	130,909	SEC↗
Perfetti Riccardo	Chief Medical Officer	P Buy	2022-03-21	2022-03-23	12,548	$1.85	$23.2K	108,948	SEC↗
Alexandria Venture Investments	10% Owner	J Other	2022-02-23	2022-02-25	300,000	—	$0	2,490,077	SEC↗
Alexandria Venture Investments	10% Owner	J Other	2022-02-23	2022-02-25	300,000	—	$0	943,977	SEC↗
Shendelman Shoshana	President and CEO	A Award deriv	2022-01-25	2022-01-27	234,616	—	$0	234,616	SEC↗
Hansard Adam	Chief Commercial Officer	A Award deriv	2022-01-07	2022-01-11	21,100	—	$0	21,100	SEC↗
Perfetti Riccardo	Chief Medical Officer	A Award deriv	2022-01-07	2022-01-11	32,100	—	$0	32,100	SEC↗
Shendelman Shoshana	President and CEO	A Award deriv	2022-01-07	2022-01-11	80,600	—	$0	80,600	SEC↗
Silberstein Charles	Chief Financial Officer	A Award deriv	2022-01-07	2022-01-11	32,000	—	$0	32,000	SEC↗
Hansard Adam	Chief Commercial Officer	A Award	2022-01-07	2022-01-11	31,700	—	$0	96,970	SEC↗
Perfetti Riccardo	Chief Medical Officer	A Award	2022-01-07	2022-01-11	48,200	—	$0	96,400	SEC↗
Shendelman Shoshana	President and CEO	A Award	2022-01-07	2022-01-11	120,900	—	$0	606,086	SEC↗
Silberstein Charles	Chief Financial Officer	A Award	2022-01-07	2022-01-11	47,900	—	$0	183,603	SEC↗
Hansard Adam	Chief Commercial Officer	A Award	2021-12-14	2022-01-11	31,700	—	$0	65,270	SEC↗
Perfetti Riccardo	Chief Medical Officer	A Award	2021-12-14	2022-01-11	48,200	—	$0	48,200	SEC↗
Shendelman Shoshana	President and CEO	A Award	2021-12-14	2022-01-11	120,900	—	$0	485,186	SEC↗
Silberstein Charles	Chief Financial Officer	A Award	2021-12-14	2022-01-11	47,900	—	$0	135,703	SEC↗
Silberstein Charles	Chief Financial Officer	A Award deriv	2021-12-14	2021-12-16	32,000	—	$0	32,000	SEC↗
Hansard Adam	Chief Commercial Officer	A Award deriv	2021-12-14	2021-12-16	21,100	—	$0	21,100	SEC↗
Perfetti Riccardo	Chief Medical Officer	A Award deriv	2021-12-14	2021-12-16	32,100	—	$0	32,100	SEC↗
Shendelman Shoshana	President and CEO	A Award deriv	2021-12-14	2021-12-16	80,600	—	$0	80,600	SEC↗
Silberstein Charles	Chief Financial Officer	A Award	2021-12-14	2021-12-16	47,900	—	$0	135,703	SEC↗
Hansard Adam	Chief Commercial Officer	A Award	2021-12-14	2021-12-16	31,700	—	$0	65,270	SEC↗
Perfetti Riccardo	Chief Medical Officer	A Award	2021-12-14	2021-12-16	48,200	—	$0	48,200	SEC↗
Shendelman Shoshana	President and CEO	A Award	2021-12-14	2021-12-16	120,900	—	$0	485,186	SEC↗
Shendelman Shoshana	President and CEO	P Buy	2021-09-14	2021-09-14	9,300	$14.49	$134.8K	364,286	SEC↗
Shendelman Shoshana	President and CEO	P Buy	2021-09-13	2021-09-14	701	$14.69	$10.3K	354,986	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise deriv	2021-08-10	2021-08-11	8,873	—	$0	94,874	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-08-10	2021-08-11	800	$16.35	$13.1K	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-08-10	2021-08-11	8,273	$15.85	$131.1K	600	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise	2021-08-10	2021-08-11	8,873	$1.44	$12.8K	8,873	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise deriv	2021-08-09	2021-08-11	15,000	—	$0	103,747	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-08-09	2021-08-11	4,700	$17.85	$83.9K	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-08-09	2021-08-11	10,300	$17.18	$177.0K	4,700	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise	2021-08-09	2021-08-11	15,000	$1.44	$21.6K	15,000	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise deriv	2021-07-29	2021-07-29	15,000	—	$0	118,747	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-07-29	2021-07-29	15,000	$17.18	$257.7K	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise	2021-07-29	2021-07-29	15,000	$1.44	$21.6K	15,000	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise deriv	2021-07-28	2021-07-29	15,000	—	$0	133,747	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise	2021-07-28	2021-07-29	15,000	$1.44	$21.6K	15,000	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-07-28	2021-07-29	15,000	$17.50	$262.5K	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise deriv	2021-07-27	2021-07-29	15,000	—	$0	148,747	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-07-27	2021-07-29	7,776	$17.05	$132.6K	7,224	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-07-27	2021-07-29	7,224	$17.39	$125.6K	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise	2021-07-27	2021-07-29	15,000	$1.44	$21.6K	15,000	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise deriv	2021-07-15	2021-07-15	460	—	$0	163,747	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-07-15	2021-07-15	460	$19.54	$9.0K	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise	2021-07-15	2021-07-15	460	$1.44	$662	460	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise deriv	2021-07-14	2021-07-15	460	—	$0	164,207	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise	2021-07-14	2021-07-15	460	$1.44	$662	460	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-07-14	2021-07-15	460	$20.51	$9.4K	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise deriv	2021-07-13	2021-07-15	460	—	$0	164,667	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise	2021-07-13	2021-07-15	460	$1.44	$662	460	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-07-13	2021-07-15	460	$21.25	$9.8K	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise deriv	2021-06-30	2021-06-30	460	—	$0	165,127	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise	2021-06-30	2021-06-30	460	$1.44	$662	460	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-06-30	2021-06-30	160	$20.80	$3.3K	300	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-06-30	2021-06-30	300	$21.71	$6.5K	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise deriv	2021-06-29	2021-06-30	460	—	$0	165,587	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise	2021-06-29	2021-06-30	460	$1.44	$662	460	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-06-29	2021-06-30	460	$21.76	$10.0K	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise deriv	2021-06-28	2021-06-30	3,547	—	$0	166,047	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-06-28	2021-06-30	1,200	$24.01	$28.8K	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-06-28	2021-06-30	1,987	$23.51	$46.7K	1,200	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-06-28	2021-06-30	360	$21.96	$7.9K	3,187	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise	2021-06-28	2021-06-30	3,547	$1.44	$5.1K	3,547	SEC↗
Silberstein Charles	Chief Financial Officer	S Sale	2021-06-08	2021-06-10	5,047	$21.42	$108.1K	87,803	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-06-07	2021-06-07	260	$21.38	$5.6K	0	SEC↗
Perfetti Riccardo	Chief Medical Officer	S Sale	2021-06-07	2021-06-07	200	$20.43	$4.1K	260	SEC↗
Perfetti Riccardo	Chief Medical Officer	M Exercise	2021-06-07	2021-06-07	460	$1.44	$662	460	SEC↗