ARQL

ARQULE INCCIK 1019695 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for ARQL PRO

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AI insights for ARQL

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
SCHEGERIN MARC	Chief Financial Officer	9	$0	$0	2020-01-16
SCHAMBER BLAINE	VP Finance, CAO	16	$0	$0	2020-01-16
Nussbaum Ran	Director	41	$4.06M	$0	2020-01-16
Kelley Susan L.	Director	20	$60.0K	$0	2020-01-16
Pucci Paolo	Other	64	$208.3K	$0	2020-01-16
SCHWARTZ BRIAN	See Remarks	44	$29.4K	$0	2020-01-16
Lawrence Peter S	President and COO	45	$6.3K	$0	2020-01-16
Messenger William G	Director	22	$10.3K	$0	2020-01-16
LINDSAY RONALD M	Director	23	$82.4K	$0	2020-01-16
BARABE TIMOTHY C	Director	94	$0	$0	2020-01-16
LOBERG MICHAEL D	Director	140	$10.7K	$0	2020-01-16
ZENNER PATRICK J	Director	28	$115.5K	$0	2020-01-16
Weiskopf Robert J	Vice President of Finance	18	$0	$0	2019-03-12
Biotechnology Value Trading Fund OS LP	Other	3	$0	$5.18M	2018-05-30
BIOTECHNOLOGY VALUE FUND II LP	Other	3	$0	$6.91M	2018-04-18
BVF PARTNERS L P/IL	10% Owner	3	$0	$6.67M	2018-04-04
CHAN THOMAS C K	Chief Scientific Officer	1	$0	$0	2012-02-01

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
SCHAMBER BLAINE	VP Finance, CAO	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
SCHAMBER BLAINE	VP Finance, CAO	D To issuer deriv	2020-01-16	2020-01-16	49,100	—	$0	0	SEC↗
SCHAMBER BLAINE	VP Finance, CAO	D To issuer deriv	2020-01-16	2020-01-16	5,300	—	$0	0	SEC↗
SCHAMBER BLAINE	VP Finance, CAO	D To issuer deriv	2020-01-16	2020-01-16	10,000	—	$0	0	SEC↗
SCHAMBER BLAINE	VP Finance, CAO	D To issuer deriv	2020-01-16	2020-01-16	8,500	—	$0	0	SEC↗
SCHAMBER BLAINE	VP Finance, CAO	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
SCHAMBER BLAINE	VP Finance, CAO	D To issuer deriv	2020-01-16	2020-01-16	10,000	—	$0	0	SEC↗
SCHAMBER BLAINE	VP Finance, CAO	D To issuer deriv	2020-01-16	2020-01-16	32,000	—	$0	0	SEC↗
SCHAMBER BLAINE	VP Finance, CAO	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
SCHAMBER BLAINE	VP Finance, CAO	D To issuer deriv	2020-01-16	2020-01-16	16,600	—	$0	0	SEC↗
SCHWARTZ BRIAN	See Remarks	D To issuer deriv	2020-01-16	2020-01-16	130,000	—	$0	0	SEC↗
SCHWARTZ BRIAN	See Remarks	D To issuer deriv	2020-01-16	2020-01-16	260,000	—	$0	0	SEC↗
SCHWARTZ BRIAN	See Remarks	D To issuer deriv	2020-01-16	2020-01-16	107,900	—	$0	0	SEC↗
SCHWARTZ BRIAN	See Remarks	D To issuer deriv	2020-01-16	2020-01-16	40,000	—	$0	0	SEC↗
SCHWARTZ BRIAN	See Remarks	D To issuer deriv	2020-01-16	2020-01-16	65,000	—	$0	0	SEC↗
SCHWARTZ BRIAN	See Remarks	D To issuer deriv	2020-01-16	2020-01-16	314,050	—	$0	0	SEC↗
SCHWARTZ BRIAN	See Remarks	D To issuer deriv	2020-01-16	2020-01-16	140,000	—	$0	0	SEC↗
SCHWARTZ BRIAN	See Remarks	D To issuer deriv	2020-01-16	2020-01-16	12,578	—	$0	0	SEC↗
SCHWARTZ BRIAN	See Remarks	D To issuer deriv	2020-01-16	2020-01-16	21,376	—	$0	0	SEC↗
SCHWARTZ BRIAN	See Remarks	D To issuer deriv	2020-01-16	2020-01-16	106,500	—	$0	0	SEC↗
SCHWARTZ BRIAN	See Remarks	D To issuer deriv	2020-01-16	2020-01-16	108,000	—	$0	0	SEC↗
SCHWARTZ BRIAN	See Remarks	D To issuer deriv	2020-01-16	2020-01-16	147,000	—	$0	0	SEC↗
LOBERG MICHAEL D	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
LOBERG MICHAEL D	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
LOBERG MICHAEL D	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
LOBERG MICHAEL D	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
LOBERG MICHAEL D	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
LOBERG MICHAEL D	Director	D To issuer deriv	2020-01-16	2020-01-16	40,000	—	$0	0	SEC↗
LOBERG MICHAEL D	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
LOBERG MICHAEL D	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
LOBERG MICHAEL D	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
LOBERG MICHAEL D	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
SCHEGERIN MARC	CFO and Treasurer	D To issuer deriv	2020-01-16	2020-01-16	13,000	—	$0	0	SEC↗
SCHEGERIN MARC	CFO and Treasurer	D To issuer deriv	2020-01-16	2020-01-16	255,000	—	$0	0	SEC↗
SCHEGERIN MARC	CFO and Treasurer	D To issuer deriv	2020-01-16	2020-01-16	230,000	—	$0	0	SEC↗
Lawrence Peter S	President and COO	D To issuer deriv	2020-01-16	2020-01-16	60,000	—	$0	0	SEC↗
Lawrence Peter S	President and COO	D To issuer deriv	2020-01-16	2020-01-16	181,500	—	$0	0	SEC↗
Lawrence Peter S	President and COO	D To issuer deriv	2020-01-16	2020-01-16	240,000	—	$0	0	SEC↗
Lawrence Peter S	President and COO	D To issuer deriv	2020-01-16	2020-01-16	185,000	—	$0	0	SEC↗
Lawrence Peter S	President and COO	D To issuer deriv	2020-01-16	2020-01-16	300,000	—	$0	0	SEC↗
Lawrence Peter S	President and COO	D To issuer deriv	2020-01-16	2020-01-16	124,500	—	$0	0	SEC↗
Lawrence Peter S	President and COO	D To issuer deriv	2020-01-16	2020-01-16	140,500	—	$0	0	SEC↗
Lawrence Peter S	President and COO	D To issuer deriv	2020-01-16	2020-01-16	75,000	—	$0	0	SEC↗
Lawrence Peter S	President and COO	D To issuer deriv	2020-01-16	2020-01-16	368,350	—	$0	0	SEC↗
Lawrence Peter S	President and COO	D To issuer deriv	2020-01-16	2020-01-16	39,925	—	$0	0	SEC↗
Lawrence Peter S	President and COO	D To issuer deriv	2020-01-16	2020-01-16	30,877	—	$0	0	SEC↗
Lawrence Peter S	President and COO	D To issuer deriv	2020-01-16	2020-01-16	12,578	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	120,000	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	242,502	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	300,000	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	600,000	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	249,000	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	80,000	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	150,000	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	650,850	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	100,000	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	14,925	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	305,000	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	285,000	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	D To issuer deriv	2020-01-16	2020-01-16	7,578	—	$0	0	SEC↗
ZENNER PATRICK J	Director	D To issuer deriv	2020-01-16	2020-01-16	25,000	—	$0	0	SEC↗
ZENNER PATRICK J	Director	D To issuer deriv	2020-01-16	2020-01-16	25,000	—	$0	0	SEC↗
ZENNER PATRICK J	Director	D To issuer deriv	2020-01-16	2020-01-16	50,000	—	$0	0	SEC↗
ZENNER PATRICK J	Director	D To issuer deriv	2020-01-16	2020-01-16	25,000	—	$0	0	SEC↗
ZENNER PATRICK J	Director	D To issuer deriv	2020-01-16	2020-01-16	25,000	—	$0	0	SEC↗
ZENNER PATRICK J	Director	D To issuer deriv	2020-01-16	2020-01-16	25,000	—	$0	0	SEC↗
ZENNER PATRICK J	Director	D To issuer deriv	2020-01-16	2020-01-16	25,000	—	$0	0	SEC↗
ZENNER PATRICK J	Director	D To issuer deriv	2020-01-16	2020-01-16	25,000	—	$0	0	SEC↗
ZENNER PATRICK J	Director	D To issuer deriv	2020-01-16	2020-01-16	25,000	—	$0	0	SEC↗
LINDSAY RONALD M	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
LINDSAY RONALD M	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
LINDSAY RONALD M	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
LINDSAY RONALD M	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
LINDSAY RONALD M	Director	D To issuer deriv	2020-01-16	2020-01-16	40,000	—	$0	0	SEC↗
LINDSAY RONALD M	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
LINDSAY RONALD M	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
LINDSAY RONALD M	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
LINDSAY RONALD M	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
LINDSAY RONALD M	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Nussbaum Ran	Director	D To issuer deriv	2020-01-16	2020-01-16	40,000	—	$0	0	SEC↗
Nussbaum Ran	Director	D To issuer deriv	2020-01-16	2020-01-16	30,000	—	$0	0	SEC↗
Nussbaum Ran	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
Kelley Susan L.	Director	D To issuer deriv	2020-01-16	2020-01-16	40,000	—	$0	0	SEC↗
Kelley Susan L.	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
Kelley Susan L.	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
Kelley Susan L.	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Kelley Susan L.	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Kelley Susan L.	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Kelley Susan L.	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Kelley Susan L.	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Kelley Susan L.	Director	D To issuer deriv	2020-01-16	2020-01-16	30,000	—	$0	0	SEC↗
Kelley Susan L.	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
BARABE TIMOTHY C	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
BARABE TIMOTHY C	Director	D To issuer deriv	2020-01-16	2020-01-16	40,000	—	$0	0	SEC↗
BARABE TIMOTHY C	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
BARABE TIMOTHY C	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
BARABE TIMOTHY C	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
BARABE TIMOTHY C	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
BARABE TIMOTHY C	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
BARABE TIMOTHY C	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
BARABE TIMOTHY C	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
BARABE TIMOTHY C	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Messenger William G	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
Messenger William G	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Messenger William G	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Messenger William G	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Messenger William G	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Messenger William G	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Messenger William G	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
Messenger William G	Director	D To issuer deriv	2020-01-16	2020-01-16	40,000	—	$0	0	SEC↗
Messenger William G	Director	D To issuer deriv	2020-01-16	2020-01-16	15,000	—	$0	0	SEC↗
Messenger William G	Director	D To issuer deriv	2020-01-16	2020-01-16	20,000	—	$0	0	SEC↗
SCHAMBER BLAINE	VP Finance, CAO	U Tender	2020-01-16	2020-01-16	57,774	$20.00	$1.16M	0	SEC↗
SCHWARTZ BRIAN	See Remarks	U Tender	2020-01-16	2020-01-16	289,838	$20.00	$5.80M	0	SEC↗
LOBERG MICHAEL D	Director	U Tender	2020-01-16	2020-01-16	188,062	$20.00	$3.76M	0	SEC↗
SCHEGERIN MARC	CFO and Treasurer	U Tender	2020-01-16	2020-01-16	23,001	$20.00	$460.0K	0	SEC↗
Lawrence Peter S	President and COO	U Tender	2020-01-16	2020-01-16	314,593	$20.00	$6.29M	0	SEC↗
Pucci Paolo	Chief Executive Officer	U Tender	2020-01-16	2020-01-16	1,235,782	$20.00	$24.72M	0	SEC↗
ZENNER PATRICK J	Director	U Tender	2020-01-16	2020-01-16	122,216	$20.00	$2.44M	0	SEC↗
LINDSAY RONALD M	Director	U Tender	2020-01-16	2020-01-16	60,800	$20.00	$1.22M	0	SEC↗
Nussbaum Ran	Director	U Tender	2020-01-16	2020-01-16	2,319,920	$20.00	$46.40M	0	SEC↗
Nussbaum Ran	Director	U Tender	2020-01-16	2020-01-16	4,290,550	$20.00	$85.81M	0	SEC↗
Nussbaum Ran	Director	U Tender	2020-01-16	2020-01-16	2,088,816	$20.00	$41.78M	0	SEC↗
Nussbaum Ran	Director	U Tender	2020-01-16	2020-01-16	36,923	$20.00	$738.5K	0	SEC↗
Nussbaum Ran	Director	U Tender	2020-01-16	2020-01-16	8,611	$20.00	$172.2K	0	SEC↗
Kelley Susan L.	Director	U Tender	2020-01-16	2020-01-16	50,000	$20.00	$1.00M	0	SEC↗
BARABE TIMOTHY C	Director	U Tender	2020-01-16	2020-01-16	146,897	$20.00	$2.94M	0	SEC↗
Messenger William G	Director	U Tender	2020-01-16	2020-01-16	20,000	$20.00	$400.0K	0	SEC↗
Nussbaum Ran	Director	M Exercise deriv	2019-12-24	2019-12-27	400,558	—	$0	0	SEC↗
Nussbaum Ran	Director	M Exercise deriv	2019-12-24	2019-12-27	823,632	—	$0	0	SEC↗
Nussbaum Ran	Director	M Exercise deriv	2019-12-24	2019-12-27	445,524	—	$0	0	SEC↗
Nussbaum Ran	Director	F Tax w/h	2019-12-24	2019-12-27	71,674	$20.11	$1.44M	4,290,550	SEC↗
Nussbaum Ran	Director	M Exercise	2019-12-24	2019-12-27	445,524	$1.75	$779.7K	2,358,690	SEC↗
Nussbaum Ran	Director	F Tax w/h	2019-12-24	2019-12-27	34,857	$20.11	$701.0K	2,088,816	SEC↗
Nussbaum Ran	Director	M Exercise	2019-12-24	2019-12-27	823,632	$1.75	$1.44M	4,362,224	SEC↗
Nussbaum Ran	Director	F Tax w/h	2019-12-24	2019-12-27	38,770	$20.11	$779.7K	2,319,920	SEC↗
Nussbaum Ran	Director	M Exercise	2019-12-24	2019-12-27	400,558	$1.75	$701.0K	2,123,673	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	M Exercise deriv	2019-12-18	2019-12-20	90,000	—	$0	0	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	M Exercise deriv	2019-12-18	2019-12-20	96,922	—	$0	0	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	M Exercise deriv	2019-12-18	2019-12-20	64,124	—	$0	0	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	M Exercise deriv	2019-12-18	2019-12-20	100,000	—	$0	0	SEC↗
SCHEGERIN MARC	Chief Financial Officer	M Exercise deriv	2019-12-18	2019-12-20	15,000	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise deriv	2019-12-18	2019-12-20	225,000	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise deriv	2019-12-18	2019-12-20	302,422	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise deriv	2019-12-18	2019-12-20	285,075	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise deriv	2019-12-18	2019-12-20	360,000	—	$0	0	SEC↗
Lawrence Peter S	President and COO	M Exercise deriv	2019-12-18	2019-12-20	115,075	—	$0	0	SEC↗
Lawrence Peter S	President and COO	M Exercise deriv	2019-12-18	2019-12-20	92,623	—	$0	0	SEC↗
Lawrence Peter S	President and COO	M Exercise deriv	2019-12-18	2019-12-20	37,500	—	$0	0	SEC↗
Lawrence Peter S	President and COO	M Exercise deriv	2019-12-18	2019-12-20	135,172	—	$0	0	SEC↗
Lawrence Peter S	President and COO	M Exercise deriv	2019-12-18	2019-12-20	115,380	—	$0	0	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	F Tax w/h	2019-12-18	2019-12-20	178,495	$20.11	$3.59M	289,838	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	M Exercise	2019-12-18	2019-12-20	100,000	$1.79	$179.0K	468,333	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	M Exercise	2019-12-18	2019-12-20	64,124	$2.51	$161.0K	368,333	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	M Exercise	2019-12-18	2019-12-20	96,922	$7.95	$770.5K	304,209	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	M Exercise	2019-12-18	2019-12-20	90,000	$3.42	$307.8K	207,287	SEC↗
SCHEGERIN MARC	Chief Financial Officer	F Tax w/h	2019-12-18	2019-12-20	7,706	$20.11	$155.0K	22,303	SEC↗
SCHEGERIN MARC	Chief Financial Officer	M Exercise	2019-12-18	2019-12-20	15,000	$2.52	$37.8K	30,009	SEC↗
Pucci Paolo	Chief Executive Officer	F Tax w/h	2019-12-18	2019-12-20	646,639	$20.11	$13.00M	1,235,245	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise	2019-12-18	2019-12-20	360,000	$1.79	$644.4K	1,881,884	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise	2019-12-18	2019-12-20	285,075	$6.70	$1.91M	1,521,884	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise	2019-12-18	2019-12-20	302,422	$7.95	$2.40M	1,236,809	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise	2019-12-18	2019-12-20	225,000	$3.42	$769.5K	934,387	SEC↗
Lawrence Peter S	President and COO	M Exercise	2019-12-18	2019-12-20	115,075	$6.70	$771.0K	457,900	SEC↗
Lawrence Peter S	President and COO	M Exercise	2019-12-18	2019-12-20	115,380	$3.42	$394.6K	207,743	SEC↗
Lawrence Peter S	President and COO	M Exercise	2019-12-18	2019-12-20	135,172	$7.95	$1.07M	342,915	SEC↗
Lawrence Peter S	President and COO	M Exercise	2019-12-18	2019-12-20	92,623	$2.51	$232.5K	550,613	SEC↗
Lawrence Peter S	President and COO	F Tax w/h	2019-12-18	2019-12-20	273,520	$20.11	$5.50M	314,593	SEC↗
Lawrence Peter S	President and COO	M Exercise	2019-12-18	2019-12-20	37,500	$1.16	$43.5K	588,113	SEC↗
ZENNER PATRICK J	Director	M Exercise deriv	2019-09-24	2019-09-25	25,000	—	$0	0	SEC↗
ZENNER PATRICK J	Director	M Exercise	2019-09-24	2019-09-25	25,000	$6.14	$153.5K	122,216	SEC↗
Lawrence Peter S	President and COO	M Exercise deriv	2019-09-16	2019-09-17	14,620	—	$0	115,380	SEC↗
Lawrence Peter S	President and COO	M Exercise	2019-09-16	2019-09-17	14,620	$3.42	$50.0K	92,363	SEC↗
Nussbaum Ran	Director	X Exercise deriv	2019-09-12	2019-09-16	27,442	—	$0	400,558	SEC↗
Nussbaum Ran	Director	X Exercise deriv	2019-09-12	2019-09-16	56,368	—	$0	823,632	SEC↗
Nussbaum Ran	Director	X Exercise deriv	2019-09-12	2019-09-16	30,476	—	$0	445,524	SEC↗
Nussbaum Ran	Director	X Exercise	2019-09-12	2019-09-16	30,476	$1.75	$53.3K	1,913,166	SEC↗
Nussbaum Ran	Director	X Exercise	2019-09-12	2019-09-16	56,368	$1.75	$98.6K	3,538,592	SEC↗
Nussbaum Ran	Director	X Exercise	2019-09-12	2019-09-16	27,442	$1.75	$48.0K	1,723,115	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise deriv	2019-09-11	2019-09-12	5,000	—	$0	7,578	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise	2019-09-11	2019-09-12	5,000	$7.95	$39.8K	707,417	SEC↗
SCHAMBER BLAINE	Other	M Exercise deriv	2019-08-15	2019-08-19	5,300	—	$0	0	SEC↗
SCHAMBER BLAINE	Other	M Exercise deriv	2019-08-15	2019-08-19	3,250	—	$0	0	SEC↗
SCHAMBER BLAINE	Other	M Exercise	2019-08-15	2019-08-19	3,250	$1.16	$3.8K	49,967	SEC↗
SCHAMBER BLAINE	Other	M Exercise	2019-08-15	2019-08-19	5,300	$3.42	$18.1K	55,267	SEC↗
Nussbaum Ran	Director	P Buy	2019-06-27	2019-07-01	36,923	$9.75	$360.0K	36,923	SEC↗
Nussbaum Ran	Director	P Buy	2019-06-27	2019-07-01	72,205	$9.75	$704.0K	1,882,690	SEC↗
Nussbaum Ran	Director	P Buy	2019-06-27	2019-07-01	65,016	$9.75	$633.9K	1,695,673	SEC↗
Nussbaum Ran	Director	P Buy	2019-06-27	2019-07-01	133,548	$9.75	$1.30M	3,482,224	SEC↗
SCHEGERIN MARC	Chief Financial Officer	M Exercise deriv	2019-06-06	2019-06-10	10,000	—	$0	270,000	SEC↗
SCHEGERIN MARC	Chief Financial Officer	M Exercise	2019-06-06	2019-06-10	10,000	$2.52	$25.2K	13,039	SEC↗
BARABE TIMOTHY C	Director	A Award deriv	2019-05-14	2019-05-15	40,000	—	$0	40,000	SEC↗
Kelley Susan L.	Director	A Award deriv	2019-05-14	2019-05-15	40,000	—	$0	40,000	SEC↗
LINDSAY RONALD M	Director	A Award deriv	2019-05-14	2019-05-15	40,000	—	$0	40,000	SEC↗
LOBERG MICHAEL D	Director	A Award deriv	2019-05-14	2019-05-15	40,000	—	$0	40,000	SEC↗
Messenger William G	Director	A Award deriv	2019-05-14	2019-05-15	40,000	—	$0	40,000	SEC↗
Nussbaum Ran	Director	A Award deriv	2019-05-14	2019-05-15	40,000	—	$0	40,000	SEC↗
ZENNER PATRICK J	Director	A Award deriv	2019-05-14	2019-05-15	50,000	—	$0	50,000	SEC↗
LINDSAY RONALD M	Director	M Exercise deriv	2019-04-15	2019-04-16	10,000	—	$0	0	SEC↗
LINDSAY RONALD M	Director	M Exercise	2019-04-15	2019-04-16	10,000	$3.87	$38.7K	60,800	SEC↗
LOBERG MICHAEL D	Director	M Exercise deriv	2019-04-10	2019-04-11	10,000	—	$0	0	SEC↗
LOBERG MICHAEL D	Director	M Exercise	2019-04-10	2019-04-11	10,000	$3.87	$38.7K	172,514	SEC↗
Messenger William G	Director	M Exercise deriv	2019-04-09	2019-04-11	10,000	—	$0	0	SEC↗
Messenger William G	Director	M Exercise	2019-04-09	2019-04-11	10,000	$3.87	$38.7K	20,000	SEC↗
SCHAMBER BLAINE	VP Finance, CAO	A Award deriv	2019-04-08	2019-04-09	20,000	—	$0	20,000	SEC↗
ZENNER PATRICK J	Director	M Exercise deriv	2019-04-05	2019-04-08	15,000	—	$0	0	SEC↗
ZENNER PATRICK J	Director	M Exercise	2019-04-05	2019-04-08	15,000	$3.87	$58.0K	97,216	SEC↗
BARABE TIMOTHY C	Director	M Exercise deriv	2019-04-04	2019-04-08	10,000	—	$0	0	SEC↗
BARABE TIMOTHY C	Director	M Exercise	2019-04-04	2019-04-08	10,000	$3.87	$38.7K	146,897	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise deriv	2019-03-15	2019-03-18	50,000	—	$0	242,502	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise	2019-03-15	2019-03-18	50,000	$1.16	$58.0K	618,208	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	A Award deriv	2019-03-12	2019-03-14	130,000	—	$0	130,000	SEC↗
Weiskopf Robert J	Chief Financial Officer	A Award deriv	2019-03-12	2019-03-14	80,000	—	$0	80,000	SEC↗
Pucci Paolo	Chief Executive Officer	A Award deriv	2019-03-12	2019-03-14	300,000	—	$0	300,000	SEC↗
Lawrence Peter S	President and COO	A Award deriv	2019-03-12	2019-03-14	150,000	—	$0	150,000	SEC↗
Pucci Paolo	Chief Executive Officer	A Award deriv	2019-01-15	2019-01-17	650,850	—	$0	650,850	SEC↗
Lawrence Peter S	President and COO	A Award deriv	2019-01-15	2019-01-17	368,350	—	$0	368,350	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	A Award deriv	2019-01-15	2019-01-17	314,050	—	$0	314,050	SEC↗
Weiskopf Robert J	Chief Financial Officer	A Award deriv	2019-01-15	2019-01-17	100,000	—	$0	100,000	SEC↗
Lawrence Peter S	President and COO	A Award deriv	2018-07-23	2018-07-25	75,000	—	$0	75,000	SEC↗
Pucci Paolo	Chief Executive Officer	A Award deriv	2018-07-23	2018-07-25	150,000	—	$0	150,000	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	A Award deriv	2018-07-23	2018-07-25	65,000	—	$0	65,000	SEC↗
Weiskopf Robert J	Chief Financial Officer	A Award deriv	2018-07-23	2018-07-25	7,500	—	$0	7,500	SEC↗
Nussbaum Ran	Director	P Buy	2018-07-13	2018-10-22	89,676	$5.50	$493.2K	3,348,676	SEC↗
Nussbaum Ran	Director	P Buy	2018-07-13	2018-10-22	48,485	$5.50	$266.7K	1,810,485	SEC↗
Nussbaum Ran	Director	P Buy	2018-07-13	2018-10-22	43,657	$5.50	$240.1K	1,630,657	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	M Exercise deriv	2018-06-13	2018-06-14	200,000	—	$0	0	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	F Tax w/h	2018-06-13	2018-06-14	148,569	$5.18	$769.6K	97,169	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	M Exercise	2018-06-13	2018-06-14	200,000	$3.62	$724.0K	245,738	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise deriv	2018-06-08	2018-06-11	101,264	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise deriv	2018-06-08	2018-06-11	398,736	—	$0	0	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise	2018-06-08	2018-06-11	101,264	$3.95	$400.0K	521,758	SEC↗
Pucci Paolo	Chief Executive Officer	M Exercise	2018-06-08	2018-06-11	398,736	$3.95	$1.58M	920,494	SEC↗
Pucci Paolo	Chief Executive Officer	F Tax w/h	2018-06-08	2018-06-11	352,286	$5.78	$2.04M	568,208	SEC↗
Biotechnology Value Trading Fu	Other	S Sale	2018-05-30	2018-06-01	312,266	$5.00	$1.56M	3,186,044	SEC↗
Biotechnology Value Trading Fu	Other	S Sale	2018-05-30	2018-06-01	547,860	$5.00	$2.74M	4,682,669	SEC↗
Biotechnology Value Trading Fu	Other	S Sale	2018-05-30	2018-06-01	175,813	$5.00	$879.1K	771,305	SEC↗
Pucci Paolo	Chief Executive Officer	P Buy	2018-05-18	2018-05-18	15,000	$3.39	$50.9K	420,494	SEC↗
Nussbaum Ran	Director	P Buy	2018-05-18	2018-05-18	8,611	$3.29	$28.3K	8,611	SEC↗
Nussbaum Ran	Director	P Buy	2018-05-18	2018-05-22	8,611	$3.29	$28.3K	8,611	SEC↗
ZENNER PATRICK J	Director	P Buy	2018-05-14	2018-05-15	8,446	$2.96	$25.0K	82,216	SEC↗
LINDSAY RONALD M	Director	P Buy	2018-05-11	2018-05-15	6,900	$2.69	$18.6K	50,800	SEC↗
LINDSAY RONALD M	Director	P Buy	2018-05-10	2018-05-11	23,900	$2.67	$63.8K	43,900	SEC↗
Pucci Paolo	Chief Executive Officer	P Buy	2018-05-10	2018-05-11	1,300	$2.64	$3.4K	405,494	SEC↗
BARABE TIMOTHY C	Director	A Award deriv	2018-05-08	2018-05-10	20,000	—	$0	20,000	SEC↗
Kelley Susan L.	Director	A Award deriv	2018-05-08	2018-05-10	20,000	—	$0	20,000	SEC↗
LINDSAY RONALD M	Director	A Award deriv	2018-05-08	2018-05-10	20,000	—	$0	20,000	SEC↗
LOBERG MICHAEL D	Director	A Award deriv	2018-05-08	2018-05-10	20,000	—	$0	20,000	SEC↗
Messenger William G	Director	A Award deriv	2018-05-08	2018-05-10	20,000	—	$0	20,000	SEC↗
Nussbaum Ran	Director	A Award deriv	2018-05-08	2018-05-10	20,000	—	$0	20,000	SEC↗
ZENNER PATRICK J	Director	A Award deriv	2018-05-08	2018-05-10	25,000	—	$0	25,000	SEC↗
Lawrence Peter S	President & COO	A Award deriv	2018-05-08	2018-05-11	60,000	—	$0	60,000	SEC↗
Pucci Paolo	Chief Executive Officer	A Award deriv	2018-05-08	2018-05-11	80,000	—	$0	80,000	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	A Award deriv	2018-05-08	2018-05-11	40,000	—	$0	40,000	SEC↗
Nussbaum Ran	Director	J Other deriv	2018-05-08	2018-05-25	476,000	—	$0	476,000	SEC↗
Nussbaum Ran	Director	J Other deriv	2018-05-08	2018-05-25	428,000	—	$0	428,000	SEC↗
Nussbaum Ran	Director	J Other deriv	2018-05-08	2018-05-25	880,000	—	$0	880,000	SEC↗
Nussbaum Ran	Director	J Other	2018-05-08	2018-05-25	1,587,000	—	$0	1,587,000	SEC↗
Nussbaum Ran	Director	J Other	2018-05-08	2018-05-25	1,762,000	—	$0	1,762,000	SEC↗
Nussbaum Ran	Director	J Other	2018-05-08	2018-05-25	3,259,000	—	$0	3,259,000	SEC↗
BIOTECHNOLOGY VALUE FUND II LP	Other	S Sale	2018-04-18	2018-04-20	1,204,668	$3.10	$3.73M	5,230,529	SEC↗
BIOTECHNOLOGY VALUE FUND II LP	Other	S Sale	2018-04-18	2018-04-20	217,256	$3.10	$673.5K	947,118	SEC↗
BIOTECHNOLOGY VALUE FUND II LP	Other	S Sale	2018-04-18	2018-04-20	808,449	$3.10	$2.51M	3,498,310	SEC↗
BVF PARTNERS L P/IL	10% Owner	S Sale	2018-04-04	2018-04-06	214,336	$2.90	$621.6K	1,164,374	SEC↗
BVF PARTNERS L P/IL	10% Owner	S Sale	2018-04-04	2018-04-06	817,611	$2.90	$2.37M	4,306,759	SEC↗
BVF PARTNERS L P/IL	10% Owner	S Sale	2018-04-04	2018-04-06	1,269,634	$2.90	$3.68M	6,435,197	SEC↗
Lawrence Peter S	President & COO	A Award deriv	2018-01-16	2018-05-10	124,500	—	$0	124,500	SEC↗
Pucci Paolo	Chief Executive Officer	A Award deriv	2018-01-16	2018-05-10	249,000	—	$0	249,000	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	A Award deriv	2018-01-16	2018-05-10	107,900	—	$0	107,900	SEC↗
Weiskopf Robert J	Chief Financial Officer	A Award deriv	2018-01-16	2018-05-10	62,250	—	$0	62,250	SEC↗
Nussbaum Ran	Director	A Award deriv	2017-11-08	2017-11-09	30,000	—	$0	30,000	SEC↗
Pucci Paolo	Chief Executive Officer	P Buy	2017-09-07	2017-09-08	1,101	$1.15	$1.3K	404,194	SEC↗
Pucci Paolo	Chief Executive Officer	P Buy	2017-09-06	2017-09-07	16,397	$1.15	$18.9K	403,093	SEC↗
Pucci Paolo	Chief Executive Officer	P Buy	2017-09-05	2017-09-06	19,156	$1.14	$21.8K	386,696	SEC↗
Pucci Paolo	Chief Executive Officer	P Buy	2017-08-29	2017-08-31	300	$1.05	$315	367,540	SEC↗
Pucci Paolo	Chief Executive Officer	P Buy	2017-08-28	2017-08-29	2,970	$1.05	$3.1K	367,240	SEC↗
Pucci Paolo	Other	P Buy	2017-08-25	2017-08-28	701	$1.05	$736	364,270	SEC↗
Pucci Paolo	Other	P Buy	2017-08-24	2017-08-28	8,791	$1.05	$9.2K	363,569	SEC↗
LOBERG MICHAEL D	Director	A Award	2017-06-26	2017-06-27	1,000	$1.25	$1.3K	162,514	SEC↗
BARABE TIMOTHY C	Director	A Award deriv	2017-05-23	2017-05-24	20,000	—	$0	20,000	SEC↗
Kelley Susan L.	Director	A Award deriv	2017-05-23	2017-05-24	20,000	—	$0	20,000	SEC↗
LINDSAY RONALD M	Director	A Award deriv	2017-05-23	2017-05-24	20,000	—	$0	20,000	SEC↗
LOBERG MICHAEL D	Director	A Award deriv	2017-05-23	2017-05-24	20,000	—	$0	20,000	SEC↗
Messenger William G	Director	A Award deriv	2017-05-23	2017-05-24	20,000	—	$0	20,000	SEC↗
ZENNER PATRICK J	Director	A Award deriv	2017-05-23	2017-05-24	25,000	—	$0	25,000	SEC↗
LOBERG MICHAEL D	Director	A Award	2017-05-23	2017-05-24	813	$1.23	$1000	161,514	SEC↗
LOBERG MICHAEL D	Director	A Award	2017-05-18	2017-05-22	2,561	$1.22	$3.1K	160,701	SEC↗
LOBERG MICHAEL D	Director	A Award	2017-04-26	2017-04-27	618	$1.01	$624	158,140	SEC↗
LOBERG MICHAEL D	Director	A Award	2017-03-21	2017-03-22	847	$1.18	$999	157,522	SEC↗
LOBERG MICHAEL D	Director	A Award	2017-03-01	2017-03-02	480	$1.30	$624	155,651	SEC↗
BARABE TIMOTHY C	Director	A Award	2017-02-18	2017-02-21	5,000	$1.20	$6.0K	136,897	SEC↗
LOBERG MICHAEL D	Director	A Award	2017-02-18	2017-02-21	2,604	$1.20	$3.1K	155,171	SEC↗
Lawrence Peter S	President & COO	A Award deriv	2017-01-17	2017-01-18	185,000	—	$0	185,000	SEC↗
Pucci Paolo	Chief Executive Officer	A Award deriv	2017-01-17	2017-01-18	300,000	—	$0	300,000	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	A Award deriv	2017-01-17	2017-01-18	130,000	—	$0	130,000	SEC↗
Weiskopf Robert J	Chief Financial Officer	A Award deriv	2017-01-17	2017-01-18	95,000	—	$0	95,000	SEC↗
BARABE TIMOTHY C	Director	A Award	2017-01-17	2017-01-18	784	$1.53	$1.2K	131,897	SEC↗
LOBERG MICHAEL D	Director	A Award	2017-01-17	2017-01-18	653	$1.53	$999	152,567	SEC↗
Lawrence Peter S	President & COO	F Tax w/h	2017-01-14	2017-01-18	2,872	$1.58	$4.5K	77,743	SEC↗
SCHWARTZ BRIAN	Chief Medical Officer	F Tax w/h	2017-01-14	2017-01-18	2,847	$1.58	$4.5K	45,738	SEC↗