Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
$1.19M
3 trades · 2 insiders
Net · 90d
$-1.19M
Insiders on file
24
Daily buy vs sell · 90 days
■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Walsh Kathleen E | Director | 7 | $0 | $0 | 2033-06-06 |
| Evans John M. | Chief Executive Officer | 173 | $0 | $39.82M | 2026-10-16 |
| Cavanagh Bethany J | SVP, Finance and Treasurer | 15 | $0 | $713.7K | 2026-10-01 |
| Ciaramella Giuseppe | President and CSO | 117 | $0 | $28.64M | 2026-09-24 |
| Simon Amy | Chief Medical Officer | 25 | $0 | $2.93M | 2026-07-27 |
| FMR LLC | Other | 61 | $0 | $40.83M | 2026-06-26 |
| Fishman Mark | Director | 9 | $0 | $0 | 2026-06-03 |
| Guindo Chirfi | Director | 3 | $0 | $0 | 2026-06-03 |
| Shaw Christi | Director | 4 | $0 | $0 | 2026-06-03 |
| COOPER GRAHAM K | Director | 28 | $0 | $1.60M | 2026-06-03 |
| MARAGANORE JOHN | Director | 6 | $0 | $0 | 2026-06-03 |
| Bellon Christine | Chief Legal Officer | 37 | $0 | $1.90M | 2026-04-01 |
| Emany Sravan Kumar | Chief Financial Officer | 5 | $0 | $170.6K | 2026-03-31 |
| Ho Carole | Director | 5 | $0 | $0 | 2025-06-04 |
| Burrell Terry-Ann | Chief Financial Officer | 54 | $0 | $15.69M | 2024-04-26 |
| Burow Kristina | Director | 29 | $0 | $0 | 2023-06-06 |
| ARCH Venture Partners IX, L.P. | 10% Owner | 5 | $0 | $0 | 2021-06-30 |
| BYBEE CLINTON | 10% Owner | 18 | $0 | $0 | 2021-06-29 |
| ARCH Venture Fund IX, L.P. | 10% Owner | 4 | $0 | $0 | 2021-03-31 |
| NELSEN ROBERT | Director, 10% Owner | 17 | $0 | $0 | 2021-03-31 |
| ARCH Venture Partners IX Overage, L.P. | 10% Owner | 8 | $0 | $0 | 2020-02-10 |
| Green Jeremy | 10% Owner | 2 | $0 | $0 | 2020-02-10 |
| PS Management GP, LLC | 10% Owner | 5 | $0 | $608.05M | 2014-01-31 |
| Pershing Square Capital Management, L.P. | 10% Owner | 2 | $0 | $0 | 2013-07-01 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Walsh Kathleen E | Director | A Award deriv | 2033-06-06 | 2023-06-08 | 16,532 | — | $0 | 16,532 | SEC↗ |
| Evans John M. | CEO, Director | M Exercise deriv | 2026-10-16 | 2026-10-16 | 25,000 | — | $0 | 155,804 | SEC↗ |
| Evans John M. | CEO, Director | S Sale | 2026-10-16 | 2026-10-16 | 25,000 | $23.98 | $599.6K | 1,047,205 | SEC↗ |
| Evans John M. | CEO, Director | M Exercise | 2026-10-16 | 2026-10-16 | 25,000 | $1.03 | $25.8K | 1,072,205 | SEC↗ |
| Evans John M. | CEO, Director | M Exercise deriv | 2026-10-15 | 2026-10-16 | 25,000 | — | $0 | 180,804 | SEC↗ |
| Evans John M. | CEO, Director | S Sale | 2026-10-15 | 2026-10-16 | 25,000 | $23.57 | $589.1K | 1,047,205 | SEC↗ |
| Evans John M. | CEO, Director | M Exercise | 2026-10-15 | 2026-10-16 | 25,000 | $1.03 | $25.8K | 1,072,205 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | S Sale | 2026-10-01 | 2026-10-02 | 187 | $24.41 | $4.6K | 50,984 | SEC↗ |
| Ciaramella Giuseppe | President | G Gift | 2026-09-24 | 2026-09-25 | 123,407 | — | $0 | 130,504 | SEC↗ |
| Ciaramella Giuseppe | President | G Gift | 2026-09-24 | 2026-09-25 | 123,407 | — | $0 | 130,504 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2026-07-27 | 2026-07-29 | 16,667 | $25.74 | $429.0K | 85,696 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2026-07-27 | 2026-07-29 | 16,667 | $25.74 | $429.0K | 85,696 | SEC↗ |
| Evans John M. | CEO | M Exercise deriv | 2026-06-30 | 2026-07-01 | 25,000 | — | $0 | 205,804 | SEC↗ |
| Evans John M. | CEO | S Sale | 2026-06-30 | 2026-07-01 | 1,900 | $34.84 | $66.2K | 1,047,205 | SEC↗ |
| Evans John M. | CEO | S Sale | 2026-06-30 | 2026-07-01 | 23,100 | $34.26 | $791.4K | 1,049,105 | SEC↗ |
| Evans John M. | CEO | M Exercise | 2026-06-30 | 2026-07-01 | 25,000 | $1.03 | $25.8K | 1,072,205 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2026-06-30 | 2026-07-02 | 373 | $34.73 | $13.0K | 102,363 | SEC↗ |
| Evans John M. | CEO | M Exercise deriv | 2026-06-29 | 2026-07-01 | 6,337 | — | $0 | 230,804 | SEC↗ |
| Evans John M. | CEO | M Exercise deriv | 2026-06-29 | 2026-07-01 | 18,663 | — | $0 | 9 | SEC↗ |
| Evans John M. | CEO | M Exercise | 2026-06-29 | 2026-07-01 | 18,663 | $0.67 | $12.5K | 1,065,868 | SEC↗ |
| Evans John M. | CEO | M Exercise | 2026-06-29 | 2026-07-01 | 6,337 | $1.03 | $6.5K | 1,072,205 | SEC↗ |
| Evans John M. | CEO | S Sale | 2026-06-29 | 2026-07-01 | 13,421 | $35.13 | $471.5K | 1,058,784 | SEC↗ |
| Evans John M. | CEO | S Sale | 2026-06-29 | 2026-07-01 | 11,579 | $35.91 | $415.8K | 1,047,205 | SEC↗ |
| FMR LLC | 10% Owner | S Sale | 2026-06-26 | 2026-06-29 | 251,488 | $35.26 | $8.87M | 854,583 | SEC↗ |
| FMR LLC | 10% Owner | S Sale | 2026-06-25 | 2026-06-29 | 33,372 | $35.12 | $1.17M | 1,106,071 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise deriv | 2026-06-17 | 2026-06-22 | 6,505 | — | $0 | 0 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise deriv | 2026-06-17 | 2026-06-22 | 29,000 | — | $0 | 56,946 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise | 2026-06-17 | 2026-06-22 | 29,000 | $1.03 | $29.9K | 253,911 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise | 2026-06-17 | 2026-06-22 | 6,505 | $0.67 | $4.4K | 224,911 | SEC↗ |
| COOPER GRAHAM K | Director | A Award deriv | 2026-06-03 | 2026-06-05 | 19,676 | — | $0 | 19,676 | SEC↗ |
| MARAGANORE JOHN | Director | A Award deriv | 2026-06-03 | 2026-06-05 | 19,676 | — | $0 | 19,676 | SEC↗ |
| Walsh Kathleen E | Director | A Award deriv | 2026-06-03 | 2026-06-05 | 19,676 | — | $0 | 19,676 | SEC↗ |
| Shaw Christi | Director | A Award deriv | 2026-06-03 | 2026-06-05 | 19,676 | — | $0 | 19,676 | SEC↗ |
| Guindo Chirfi | Director | A Award deriv | 2026-06-03 | 2026-06-05 | 19,676 | — | $0 | 19,676 | SEC↗ |
| Fishman Mark | Director | A Award deriv | 2026-06-03 | 2026-06-05 | 19,676 | — | $0 | 19,676 | SEC↗ |
| Ciaramella Giuseppe | President | S Sale | 2026-04-01 | 2026-04-06 | 11,810 | $24.58 | $290.3K | 218,406 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2026-04-01 | 2026-04-06 | 5,956 | $24.58 | $146.4K | 109,711 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | S Sale | 2026-04-01 | 2026-04-06 | 3,242 | $24.58 | $79.7K | 51,171 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2026-04-01 | 2026-04-06 | 6,700 | $24.58 | $164.7K | 102,735 | SEC↗ |
| Evans John M. | CEO | S Sale | 2026-04-01 | 2026-04-06 | 30,078 | $24.58 | $739.3K | 1,047,205 | SEC↗ |
| Evans John M. | CEO | M Exercise deriv | 2026-03-31 | 2026-04-01 | 25,000 | — | $0 | 18,672 | SEC↗ |
| Evans John M. | CEO | A Award | 2026-03-31 | 2026-04-01 | 90,000 | — | $0 | 1,076,667 | SEC↗ |
| Evans John M. | CEO | S Sale | 2026-03-31 | 2026-04-01 | 25,000 | $22.76 | $569.0K | 986,667 | SEC↗ |
| Evans John M. | CEO | M Exercise | 2026-03-31 | 2026-04-01 | 25,000 | $0.67 | $16.8K | 1,011,667 | SEC↗ |
| Ciaramella Giuseppe | President | A Award | 2026-03-31 | 2026-04-02 | 40,000 | — | $0 | 230,216 | SEC↗ |
| Emany Sravan Kumar | Chief Financial Officer | A Award | 2026-03-31 | 2026-04-02 | 31,750 | — | $0 | 105,456 | SEC↗ |
| Simon Amy | Chief Medical Officer | A Award | 2026-03-31 | 2026-04-02 | 31,750 | — | $0 | 109,114 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | A Award | 2026-03-31 | 2026-04-02 | 20,000 | — | $0 | 54,813 | SEC↗ |
| Bellon Christine | Chief Legal Officer | A Award | 2026-03-31 | 2026-04-02 | 20,000 | — | $0 | 115,667 | SEC↗ |
| Evans John M. | CEO | M Exercise deriv | 2026-03-30 | 2026-04-01 | 25,000 | — | $0 | 43,672 | SEC↗ |
| Evans John M. | CEO | M Exercise | 2026-03-30 | 2026-04-01 | 25,000 | $0.67 | $16.8K | 1,011,667 | SEC↗ |
| Evans John M. | CEO | S Sale | 2026-03-30 | 2026-04-01 | 25,000 | $22.37 | $559.3K | 986,667 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise deriv | 2026-02-24 | 2026-02-26 | 35,000 | — | $0 | 397,313 | SEC↗ |
| Ciaramella Giuseppe | President | S Sale | 2026-02-24 | 2026-02-26 | 35,000 | $32.00 | $1.12M | 190,216 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise | 2026-02-24 | 2026-02-26 | 35,000 | $17.00 | $595.0K | 225,216 | SEC↗ |
| Simon Amy | Chief Medical Officer | A Award deriv | 2026-01-31 | 2026-02-02 | 88,500 | — | $0 | 88,500 | SEC↗ |
| Evans John M. | CEO | A Award deriv | 2026-01-31 | 2026-02-02 | 180,000 | — | $0 | 180,000 | SEC↗ |
| Bellon Christine | Chief Legal Officer | A Award deriv | 2026-01-31 | 2026-02-02 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Emany Sravan Kumar | Chief Financial Officer | A Award deriv | 2026-01-31 | 2026-02-02 | 63,500 | — | $0 | 63,500 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | A Award deriv | 2026-01-31 | 2026-02-02 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Ciaramella Giuseppe | President | A Award deriv | 2026-01-31 | 2026-02-02 | 80,000 | — | $0 | 80,000 | SEC↗ |
| Evans John M. | CEO | M Exercise deriv | 2026-01-30 | 2026-02-02 | 25,000 | — | $0 | 68,672 | SEC↗ |
| Evans John M. | CEO | M Exercise | 2026-01-30 | 2026-02-02 | 25,000 | $0.67 | $16.8K | 1,011,667 | SEC↗ |
| Evans John M. | CEO | S Sale | 2026-01-30 | 2026-02-02 | 22,094 | $28.27 | $624.6K | 989,573 | SEC↗ |
| Evans John M. | CEO | S Sale | 2026-01-30 | 2026-02-02 | 2,906 | $29.00 | $84.3K | 986,667 | SEC↗ |
| Evans John M. | CEO | M Exercise deriv | 2026-01-29 | 2026-02-02 | 5,664 | — | $0 | 93,672 | SEC↗ |
| Evans John M. | CEO | M Exercise deriv | 2026-01-29 | 2026-02-02 | 19,336 | — | $0 | 0 | SEC↗ |
| Evans John M. | CEO | S Sale | 2026-01-29 | 2026-02-02 | 8,667 | $29.74 | $257.8K | 986,667 | SEC↗ |
| Evans John M. | CEO | S Sale | 2026-01-29 | 2026-02-02 | 16,333 | $29.19 | $476.8K | 995,334 | SEC↗ |
| Evans John M. | CEO | M Exercise | 2026-01-29 | 2026-02-02 | 5,664 | $0.67 | $3.8K | 1,011,667 | SEC↗ |
| Evans John M. | CEO | M Exercise | 2026-01-29 | 2026-02-02 | 19,336 | $0.67 | $13.0K | 1,006,003 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2026-01-22 | 2026-01-26 | 1,371 | $34.00 | $46.6K | 95,667 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | S Sale | 2026-01-22 | 2026-01-26 | 6,198 | $35.00 | $216.9K | 34,813 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | S Sale | 2026-01-20 | 2026-01-21 | 3,034 | $30.12 | $91.4K | 41,011 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2026-01-15 | 2026-01-20 | 559 | $35.40 | $19.8K | 97,038 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2026-01-15 | 2026-01-20 | 2,111 | $33.62 | $71.0K | 113,556 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2026-01-15 | 2026-01-20 | 15,959 | $34.72 | $554.1K | 97,597 | SEC↗ |
| Simon Amy | Chief Medical Officer | A Award | 2025-12-31 | 2026-01-05 | 12,500 | — | $0 | 77,364 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2025-12-31 | 2026-01-05 | 1,254 | $27.10 | $34.0K | 115,667 | SEC↗ |
| Emany Sravan Kumar | Chief Financial Officer | S Sale | 2025-12-31 | 2026-01-05 | 6,294 | $27.10 | $170.6K | 73,706 | SEC↗ |
| FMR LLC | 10% Owner | S Sale | 2025-10-27 | 2025-10-29 | 459 | $26.68 | $12.2K | 14 | SEC↗ |
| FMR LLC | 10% Owner | G Gift | 2025-10-06 | 2025-10-08 | 1,232,434 | — | $0 | 841,231 | SEC↗ |
| Evans John M. | CEO | M Exercise deriv | 2025-10-02 | 2025-10-03 | 25,000 | — | $0 | 19,336 | SEC↗ |
| Evans John M. | CEO | M Exercise | 2025-10-02 | 2025-10-03 | 25,000 | $0.67 | $16.8K | 1,011,667 | SEC↗ |
| Evans John M. | CEO | S Sale | 2025-10-02 | 2025-10-03 | 25,000 | $24.63 | $615.8K | 986,667 | SEC↗ |
| Evans John M. | CEO | M Exercise deriv | 2025-10-01 | 2025-10-03 | 25,000 | — | $0 | 44,336 | SEC↗ |
| Evans John M. | CEO | M Exercise | 2025-10-01 | 2025-10-03 | 25,000 | $0.67 | $16.8K | 1,011,667 | SEC↗ |
| Evans John M. | CEO | S Sale | 2025-10-01 | 2025-10-03 | 25,000 | $24.51 | $612.8K | 986,667 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2025-10-01 | 2025-10-03 | 373 | $24.53 | $9.1K | 116,921 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | S Sale | 2025-10-01 | 2025-10-03 | 467 | $24.53 | $11.5K | 44,045 | SEC↗ |
| FMR LLC | 10% Owner | S Sale | 2025-07-30 | 2025-08-01 | 48,374 | $20.50 | $991.7K | 2,073,665 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2025-07-03 | 2025-07-03 | 876 | $20.12 | $17.6K | 64,864 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2025-07-01 | 2025-07-03 | 374 | $16.94 | $6.3K | 65,740 | SEC↗ |
| COOPER GRAHAM K | Director | A Award deriv | 2025-06-04 | 2025-06-06 | 33,662 | — | $0 | 33,662 | SEC↗ |
| Ho Carole | Director | A Award deriv | 2025-06-04 | 2025-06-06 | 33,662 | — | $0 | 33,662 | SEC↗ |
| Guindo Chirfi | Director | A Award deriv | 2025-06-04 | 2025-06-06 | 33,662 | — | $0 | 33,662 | SEC↗ |
| MARAGANORE JOHN | Director | A Award deriv | 2025-06-04 | 2025-06-06 | 33,662 | — | $0 | 33,662 | SEC↗ |
| Shaw Christi | Director | A Award deriv | 2025-06-04 | 2025-06-06 | 33,662 | — | $0 | 33,662 | SEC↗ |
| Fishman Mark | Director | A Award deriv | 2025-06-04 | 2025-06-06 | 33,662 | — | $0 | 33,662 | SEC↗ |
| Walsh Kathleen E | Director | A Award deriv | 2025-06-04 | 2025-06-06 | 33,662 | — | $0 | 33,662 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2025-04-02 | 2025-04-03 | 20,997 | $17.73 | $372.3K | 65,742 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2025-04-01 | 2025-04-03 | 9,566 | $18.35 | $175.5K | 86,739 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | S Sale | 2025-04-01 | 2025-04-03 | 3,015 | $18.35 | $55.3K | 44,512 | SEC↗ |
| Ciaramella Giuseppe | President | S Sale | 2025-04-01 | 2025-04-03 | 7,434 | $18.35 | $136.4K | 190,216 | SEC↗ |
| Evans John M. | CEO | S Sale | 2025-04-01 | 2025-04-03 | 30,663 | $18.35 | $562.7K | 986,249 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2025-04-01 | 2025-04-03 | 5,674 | $18.35 | $104.1K | 117,294 | SEC↗ |
| Evans John M. | CEO | A Award | 2025-03-31 | 2025-04-02 | 77,500 | — | $0 | 1,016,159 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | A Award | 2025-03-31 | 2025-04-02 | 10,000 | — | $0 | 47,527 | SEC↗ |
| Ciaramella Giuseppe | President | A Award | 2025-03-31 | 2025-04-02 | 35,000 | — | $0 | 197,650 | SEC↗ |
| Simon Amy | Chief Medical Officer | A Award | 2025-03-31 | 2025-04-02 | 27,500 | — | $0 | 96,305 | SEC↗ |
| Bellon Christine | Chief Legal Officer | A Award | 2025-03-31 | 2025-04-02 | 20,000 | — | $0 | 122,968 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | S Sale | 2025-02-18 | 2025-02-20 | 6,287 | $35.00 | $220.0K | 37,527 | SEC↗ |
| Bellon Christine | Chief Legal Officer | M Exercise deriv | 2025-02-14 | 2025-02-19 | 9,492 | — | $0 | 0 | SEC↗ |
| Bellon Christine | Chief Legal Officer | M Exercise deriv | 2025-02-14 | 2025-02-19 | 508 | — | $0 | 10,410 | SEC↗ |
| Bellon Christine | Chief Legal Officer | M Exercise | 2025-02-14 | 2025-02-19 | 9,492 | $7.22 | $68.5K | 112,460 | SEC↗ |
| Bellon Christine | Chief Legal Officer | M Exercise | 2025-02-14 | 2025-02-19 | 508 | $7.22 | $3.7K | 112,968 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2025-02-14 | 2025-02-19 | 10,000 | $34.00 | $340.0K | 102,968 | SEC↗ |
| Evans John M. | CEO | A Award deriv | 2025-01-31 | 2025-02-03 | 155,000 | — | $0 | 155,000 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | A Award deriv | 2025-01-31 | 2025-02-03 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Simon Amy | Chief Medical Officer | A Award deriv | 2025-01-31 | 2025-02-03 | 55,000 | — | $0 | 55,000 | SEC↗ |
| Ciaramella Giuseppe | President | A Award deriv | 2025-01-31 | 2025-02-03 | 70,000 | — | $0 | 70,000 | SEC↗ |
| Bellon Christine | Chief Legal Officer | A Award deriv | 2025-01-31 | 2025-02-03 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Evans John M. | CEO | M Exercise deriv | 2025-01-30 | 2025-04-02 | 30,000 | — | $0 | 69,336 | SEC↗ |
| Evans John M. | CEO | M Exercise | 2025-01-30 | 2025-04-02 | 30,000 | $0.67 | $20.1K | 968,659 | SEC↗ |
| Evans John M. | CEO | S Sale | 2025-01-30 | 2025-02-03 | 29,800 | $26.75 | $797.1K | 908,859 | SEC↗ |
| Evans John M. | CEO | S Sale | 2025-01-30 | 2025-02-03 | 200 | $27.28 | $5.5K | 908,659 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | S Sale | 2025-01-02 | 2025-01-06 | 1,117 | $24.68 | $27.6K | 43,814 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2025-01-02 | 2025-01-06 | 1,241 | $24.68 | $30.6K | 102,968 | SEC↗ |
| Emany Sravan Kumar | Chief Financial Officer | A Award deriv | 2024-12-31 | 2025-01-02 | 160,000 | — | $0 | 160,000 | SEC↗ |
| Emany Sravan Kumar | Chief Financial Officer | A Award | 2024-12-31 | 2025-01-02 | 80,000 | — | $0 | 80,000 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise deriv | 2024-12-17 | 2024-12-19 | 53,500 | — | $0 | 6,505 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise | 2024-12-17 | 2024-12-19 | 53,500 | $0.67 | $35.8K | 162,650 | SEC↗ |
| Guindo Chirfi | Director | A Award deriv | 2024-12-02 | 2024-12-04 | 39,086 | — | $0 | 39,086 | SEC↗ |
| Ciaramella Giuseppe | President | S Sale | 2024-11-06 | 2024-11-08 | 51,110 | $26.36 | $1.35M | 109,150 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise deriv | 2024-10-14 | 2024-10-16 | 27,318 | — | $0 | 0 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise deriv | 2024-10-14 | 2024-10-16 | 1,457 | — | $0 | 0 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise deriv | 2024-10-14 | 2024-10-16 | 12,979 | — | $0 | 0 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise | 2024-10-14 | 2024-10-16 | 12,979 | $4.22 | $54.8K | 209,913 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise | 2024-10-14 | 2024-10-16 | 1,457 | $7.22 | $10.5K | 211,370 | SEC↗ |
| Ciaramella Giuseppe | President | S Sale | 2024-10-14 | 2024-10-16 | 51,110 | $26.27 | $1.34M | 160,260 | SEC↗ |
| Ciaramella Giuseppe | President | M Exercise | 2024-10-14 | 2024-10-16 | 27,318 | $0.67 | $18.3K | 196,934 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | S Sale | 2024-10-01 | 2024-10-02 | 289 | $23.48 | $6.8K | 44,931 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2024-10-01 | 2024-10-02 | 385 | $23.48 | $9.0K | 104,209 | SEC↗ |
| Evans John M. | CEO | S Sale | 2024-09-30 | 2024-10-02 | 60,000 | $24.60 | $1.48M | 938,659 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | A Award | 2024-09-30 | 2024-10-02 | 2,500 | — | $0 | 45,220 | SEC↗ |
| Cavanagh Bethany J | SVP, Finance and Treasurer | A Award deriv | 2024-08-31 | 2024-09-03 | 5,000 | — | $0 | 5,000 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2024-07-02 | 2024-07-03 | 748 | $22.95 | $17.2K | 68,805 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2024-07-01 | 2024-07-03 | 502 | $23.76 | $11.9K | 69,553 | SEC↗ |
| Evans John M. | CEO | S Sale | 2024-06-27 | 2024-06-28 | 60,000 | $24.50 | $1.47M | 998,343 | SEC↗ |
| Fishman Mark | Director | A Award deriv | 2024-06-05 | 2024-06-07 | 23,114 | — | $0 | 23,114 | SEC↗ |
| Walsh Kathleen E | Director | A Award deriv | 2024-06-05 | 2024-06-07 | 23,114 | — | $0 | 23,114 | SEC↗ |
| COOPER GRAHAM K | Director | A Award deriv | 2024-06-05 | 2024-06-07 | 23,114 | — | $0 | 23,114 | SEC↗ |
| Ho Carole | Director | A Award deriv | 2024-06-05 | 2024-06-07 | 23,114 | — | $0 | 23,114 | SEC↗ |
| MARAGANORE JOHN | Director | A Award deriv | 2024-06-05 | 2024-06-07 | 23,114 | — | $0 | 23,114 | SEC↗ |
| Shaw Christi | Director | A Award deriv | 2024-06-05 | 2024-06-07 | 23,114 | — | $0 | 23,114 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | A Award deriv | 2024-04-26 | 2024-04-29 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | A Award | 2024-04-26 | 2024-04-29 | 12,500 | — | $0 | 82,637 | SEC↗ |
| Ciaramella Giuseppe | President | A Award deriv | 2024-04-03 | 2024-04-03 | 27,318 | — | $0 | 27,318 | SEC↗ |
| Ciaramella Giuseppe | President | A Award deriv | 2024-04-03 | 2024-04-03 | 12,979 | — | $0 | 12,979 | SEC↗ |
| Evans John M. | CEO | A Award deriv | 2024-04-03 | 2024-04-03 | 53,965 | — | $0 | 53,965 | SEC↗ |
| Evans John M. | CEO | A Award deriv | 2024-04-03 | 2024-04-03 | 99,336 | — | $0 | 99,336 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2024-04-02 | 2024-04-03 | 16,530 | $30.54 | $504.8K | 70,060 | SEC↗ |
| Ciaramella Giuseppe | President | S Sale | 2024-04-01 | 2024-04-03 | 4,534 | $32.12 | $145.6K | 169,616 | SEC↗ |
| Evans John M. | CEO | S Sale | 2024-04-01 | 2024-04-03 | 18,102 | $32.13 | $581.6K | 1,058,343 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | S Sale | 2024-04-01 | 2024-04-03 | 5,446 | $32.12 | $174.9K | 70,137 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2024-04-01 | 2024-04-03 | 3,401 | $32.12 | $109.2K | 104,594 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2024-04-01 | 2024-04-03 | 7,157 | $32.13 | $230.0K | 86,590 | SEC↗ |
| Evans John M. | CEO | A Award | 2024-03-31 | 2024-04-01 | 77,500 | — | $0 | 1,076,445 | SEC↗ |
| Ciaramella Giuseppe | President | A Award | 2024-03-31 | 2024-04-02 | 35,000 | — | $0 | 174,150 | SEC↗ |
| Bellon Christine | Chief Legal Officer | A Award | 2024-03-31 | 2024-04-02 | 27,500 | — | $0 | 107,995 | SEC↗ |
| Simon Amy | Chief Medical Officer | A Award | 2024-03-31 | 2024-04-02 | 27,500 | — | $0 | 93,747 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | A Award | 2024-03-31 | 2024-04-02 | 27,500 | — | $0 | 75,583 | SEC↗ |
| Evans John M. | CEO | S Sale | 2024-03-28 | 2024-04-01 | 60,000 | $33.86 | $2.03M | 998,262 | SEC↗ |
| FMR LLC | Other | S Sale | 2024-02-14 | 2024-02-15 | 854,323 | $30.51 | $26.07M | 1,281,188 | SEC↗ |
| FMR LLC | Other | S Sale | 2024-02-14 | 2024-02-15 | 45,677 | $31.34 | $1.43M | 1,235,511 | SEC↗ |
| FMR LLC | Other | S Sale | 2024-02-13 | 2024-02-15 | 1,155 | $30.93 | $35.7K | 2,771,913 | SEC↗ |
| FMR LLC | Other | S Sale | 2024-02-13 | 2024-02-15 | 410 | $30.28 | $12.4K | 2,773,068 | SEC↗ |
| Simon Amy | Chief Medical Officer | A Award deriv | 2024-01-31 | 2024-02-02 | 55,000 | $24.40 | $1.34M | 55,000 | SEC↗ |
| Ciaramella Giuseppe | President | A Award deriv | 2024-01-31 | 2024-02-02 | 70,000 | $24.40 | $1.71M | 70,000 | SEC↗ |
| Evans John M. | CEO | A Award deriv | 2024-01-31 | 2024-02-02 | 155,000 | $24.40 | $3.78M | 155,000 | SEC↗ |
| Bellon Christine | Chief Legal Officer | A Award deriv | 2024-01-31 | 2024-02-02 | 55,000 | $24.40 | $1.34M | 55,000 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | A Award deriv | 2024-01-31 | 2024-02-02 | 55,000 | $24.40 | $1.34M | 55,000 | SEC↗ |
| Evans John M. | CEO | S Sale | 2024-01-31 | 2024-02-02 | 60,000 | $25.33 | $1.52M | 1,058,262 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2024-01-03 | 2024-01-05 | 1,907 | $26.42 | $50.4K | 80,495 | SEC↗ |
| FMR LLC | 10% Owner | J Other | 2023-12-22 | 2023-12-27 | 29,549 | — | $0 | 2,773,478 | SEC↗ |
| Shaw Christi | Director | A Award deriv | 2023-12-13 | 2023-12-14 | 39,046 | — | $0 | 39,046 | SEC↗ |
| Bellon Christine | Chief Legal Officer | M Exercise deriv | 2023-11-20 | 2023-11-22 | 5,818 | — | $0 | 10,918 | SEC↗ |
| Bellon Christine | Chief Legal Officer | M Exercise deriv | 2023-11-20 | 2023-11-22 | 4,182 | — | $0 | 9,492 | SEC↗ |
| Bellon Christine | Chief Legal Officer | M Exercise | 2023-11-20 | 2023-11-22 | 4,182 | $7.22 | $30.2K | 86,584 | SEC↗ |
| Bellon Christine | Chief Legal Officer | M Exercise | 2023-11-20 | 2023-11-22 | 5,818 | $7.22 | $42.0K | 92,402 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2023-11-20 | 2023-11-22 | 5,000 | $30.00 | $150.0K | 87,402 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2023-11-20 | 2023-11-22 | 5,000 | $31.00 | $155.0K | 82,402 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2023-10-30 | 2023-11-01 | 3,448 | $18.70 | $64.5K | 65,469 | SEC↗ |
| Ciaramella Giuseppe | President and CSO | M Exercise deriv | 2023-10-20 | 2023-10-24 | 90,900 | — | $0 | 60,005 | SEC↗ |
| Ciaramella Giuseppe | President and CSO | M Exercise | 2023-10-20 | 2023-10-24 | 90,900 | $0.67 | $60.9K | 139,150 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2023-10-02 | 2023-10-04 | 388 | $22.85 | $8.9K | 82,402 | SEC↗ |
| Ciaramella Giuseppe | President and CSO | M Exercise deriv | 2023-07-24 | 2023-07-25 | 1,206 | — | $0 | 19,002 | SEC↗ |
| Ciaramella Giuseppe | President and CSO | M Exercise | 2023-07-24 | 2023-07-25 | 1,206 | $7.22 | $8.7K | 49,456 | SEC↗ |
| Ciaramella Giuseppe | President and CSO | S Sale | 2023-07-24 | 2023-07-25 | 1,206 | $32.01 | $38.6K | 48,250 | SEC↗ |
| Ciaramella Giuseppe | President and CSO | M Exercise deriv | 2023-07-21 | 2023-07-25 | 69,438 | — | $0 | 20,208 | SEC↗ |
| Ciaramella Giuseppe | President and CSO | M Exercise deriv | 2023-07-21 | 2023-07-25 | 21,846 | — | $0 | 1,457 | SEC↗ |
| Ciaramella Giuseppe | President and CSO | S Sale | 2023-07-21 | 2023-07-25 | 155,324 | $32.06 | $4.98M | 48,250 | SEC↗ |
| Ciaramella Giuseppe | President and CSO | M Exercise | 2023-07-21 | 2023-07-25 | 69,438 | $7.22 | $501.3K | 181,728 | SEC↗ |
| Ciaramella Giuseppe | President and CSO | M Exercise | 2023-07-21 | 2023-07-25 | 21,846 | $7.22 | $157.7K | 203,574 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2023-07-10 | 2023-08-09 | 391 | $30.48 | $11.9K | 68,917 | SEC↗ |
| MARAGANORE JOHN | Director | A Award deriv | 2023-06-06 | 2023-06-08 | 16,532 | — | $0 | 16,532 | SEC↗ |
| Ho Carole | Director | A Award deriv | 2023-06-06 | 2023-06-08 | 16,532 | — | $0 | 16,532 | SEC↗ |
| Fishman Mark | Director | A Award deriv | 2023-06-06 | 2023-06-08 | 16,532 | — | $0 | 16,532 | SEC↗ |
| COOPER GRAHAM K | Director | A Award deriv | 2023-06-06 | 2023-06-08 | 16,532 | — | $0 | 16,532 | SEC↗ |
| Burow Kristina | Director | A Award deriv | 2023-06-06 | 2023-06-08 | 16,532 | — | $0 | 16,532 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | S Sale | 2023-04-04 | 2023-04-05 | 2,186 | $29.09 | $63.6K | 47,117 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2023-04-04 | 2023-04-05 | 1,161 | $29.09 | $33.8K | 69,308 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2023-04-04 | 2023-04-05 | 10,493 | $29.77 | $312.4K | 70,469 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2023-04-04 | 2023-04-05 | 1,161 | $29.09 | $33.8K | 82,790 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | S Sale | 2023-04-04 | 2023-04-05 | 1,754 | $29.09 | $51.0K | 112,290 | SEC↗ |
| Evans John M. | CEO | S Sale | 2023-04-04 | 2023-04-05 | 6,493 | $29.09 | $188.9K | 1,117,979 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | S Sale | 2023-04-03 | 2023-04-05 | 2,454 | $30.31 | $74.4K | 49,303 | SEC↗ |
| Simon Amy | Chief Medical Officer | S Sale | 2023-04-03 | 2023-04-05 | 4,445 | $30.31 | $134.7K | 80,962 | SEC↗ |
| Bellon Christine | Chief Legal Officer | S Sale | 2023-04-03 | 2023-04-05 | 931 | $30.31 | $28.2K | 83,951 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | S Sale | 2023-04-03 | 2023-04-05 | 1,918 | $30.31 | $58.1K | 114,044 | SEC↗ |
| Evans John M. | CEO | S Sale | 2023-04-03 | 2023-04-05 | 5,161 | $30.31 | $156.4K | 1,124,472 | SEC↗ |
| Evans John M. | CEO | M Exercise deriv | 2023-03-31 | 2023-03-31 | 13,850 | — | $0 | 196,904 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | A Award | 2023-03-31 | 2023-03-31 | 20,000 | — | $0 | 51,277 | SEC↗ |
| Simon Amy | Chief Medical Officer | A Award | 2023-03-31 | 2023-03-31 | 20,000 | — | $0 | 85,129 | SEC↗ |
| Evans John M. | CEO | M Exercise | 2023-03-31 | 2023-03-31 | 13,850 | $7.22 | $100.0K | 1,129,153 | SEC↗ |
| Evans John M. | CEO | A Award | 2023-03-31 | 2023-03-31 | 56,250 | — | $0 | 1,115,303 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | A Award | 2023-03-31 | 2023-03-31 | 20,000 | — | $0 | 115,962 | SEC↗ |
| Bellon Christine | Chief Legal Officer | A Award | 2023-03-31 | 2023-03-31 | 17,500 | — | $0 | 84,882 | SEC↗ |
| Bellon Christine | Chief Legal Officer | M Exercise deriv | 2023-03-30 | 2023-03-31 | 2,669 | — | $0 | 16,736 | SEC↗ |
| Bellon Christine | Chief Legal Officer | M Exercise deriv | 2023-03-30 | 2023-03-31 | 6,272 | — | $0 | 13,674 | SEC↗ |
| Bellon Christine | Chief Legal Officer | M Exercise | 2023-03-30 | 2023-03-31 | 2,669 | $7.22 | $19.3K | 67,382 | SEC↗ |
| Bellon Christine | Chief Legal Officer | M Exercise | 2023-03-30 | 2023-03-31 | 6,272 | $7.22 | $45.3K | 64,713 | SEC↗ |
| Evans John M. | CEO | L Small acq | 2023-03-06 | 2023-03-31 | 225 | — | $0 | 1,059,053 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | A Award deriv | 2023-01-31 | 2023-04-19 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | A Award deriv | 2023-01-31 | 2023-03-31 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Evans John M. | CEO | A Award deriv | 2023-01-31 | 2023-03-31 | 112,500 | — | $0 | 112,500 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | A Award deriv | 2023-01-31 | 2023-03-31 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | M Exercise deriv | 2023-01-27 | 2023-01-30 | 36,152 | — | $0 | 185,565 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | M Exercise | 2023-01-27 | 2023-01-30 | 36,152 | $13.68 | $494.6K | 67,429 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | S Sale | 2023-01-27 | 2023-01-30 | 36,152 | $45.08 | $1.63M | 31,277 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | M Exercise deriv | 2023-01-26 | 2023-01-30 | 1,102 | — | $0 | 221,717 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | S Sale | 2023-01-26 | 2023-01-30 | 1,102 | $45.16 | $49.8K | 31,277 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | M Exercise | 2023-01-26 | 2023-01-30 | 1,102 | $13.68 | $15.1K | 32,379 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | M Exercise deriv | 2023-01-24 | 2023-01-25 | 14,810 | — | $0 | 222,819 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | M Exercise | 2023-01-24 | 2023-01-25 | 14,810 | $13.68 | $202.6K | 46,087 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | S Sale | 2023-01-24 | 2023-01-25 | 14,810 | $45.01 | $666.6K | 31,277 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | M Exercise deriv | 2023-01-23 | 2023-01-25 | 5,426 | — | $0 | 237,629 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | S Sale | 2023-01-23 | 2023-01-25 | 5,426 | $45.02 | $244.3K | 31,277 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | M Exercise | 2023-01-23 | 2023-01-25 | 5,426 | $13.68 | $74.2K | 36,703 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | M Exercise deriv | 2023-01-18 | 2023-01-20 | 39,886 | — | $0 | 243,055 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | S Sale | 2023-01-18 | 2023-01-20 | 47,195 | $45.14 | $2.13M | 31,277 | SEC↗ |
| Burrell Terry-Ann | Chief Financial Officer | M Exercise | 2023-01-18 | 2023-01-20 | 39,886 | $13.68 | $545.6K | 78,472 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise deriv | 2023-01-03 | 2023-01-05 | 4,326 | — | $0 | 0 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise deriv | 2023-01-03 | 2023-01-05 | 9,106 | — | $0 | 0 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise deriv | 2023-01-03 | 2023-01-05 | 40,297 | — | $0 | 150,905 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | S Sale | 2023-01-03 | 2023-01-05 | 600 | $39.94 | $24.0K | 95,962 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise | 2023-01-03 | 2023-01-05 | 9,106 | $0.67 | $6.1K | 105,068 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise | 2023-01-03 | 2023-01-05 | 4,326 | $4.22 | $18.3K | 109,394 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise | 2023-01-03 | 2023-01-05 | 40,297 | $0.67 | $27.0K | 149,691 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | S Sale | 2023-01-03 | 2023-01-05 | 37,525 | $37.14 | $1.39M | 112,166 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | S Sale | 2023-01-03 | 2023-01-05 | 13,704 | $37.99 | $520.6K | 98,462 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | S Sale | 2023-01-03 | 2023-01-05 | 1,900 | $39.07 | $74.2K | 96,562 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise deriv | 2022-12-30 | 2023-01-03 | 4,500 | — | $0 | 191,202 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise | 2022-12-30 | 2023-01-03 | 4,500 | $0.67 | $3.0K | 95,962 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise deriv | 2022-12-12 | 2022-12-14 | 8,652 | — | $0 | 4,326 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise deriv | 2022-12-12 | 2022-12-14 | 18,211 | — | $0 | 189,491 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise deriv | 2022-12-12 | 2022-12-20 | 18,211 | — | $0 | 9,106 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise | 2022-12-12 | 2022-12-14 | 18,211 | $0.67 | $12.2K | 133,825 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | M Exercise | 2022-12-12 | 2022-12-14 | 8,652 | $4.22 | $36.5K | 142,477 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | S Sale | 2022-12-12 | 2022-12-14 | 31,699 | $42.30 | $1.34M | 110,778 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | S Sale | 2022-12-12 | 2022-12-14 | 5,383 | $43.87 | $236.2K | 91,462 | SEC↗ |
| Ciaramella Giuseppe | President & CSO | S Sale | 2022-12-12 | 2022-12-14 | 13,933 | $43.15 | $601.2K | 96,845 | SEC↗ |
| Evans John M. | CEO | S Sale | 2022-10-31 | 2022-11-02 | 7,768 | $46.19 | $358.8K | 1,073,185 | SEC↗ |
| Evans John M. | CEO | S Sale | 2022-10-31 | 2022-11-02 | 7,567 | $44.92 | $339.9K | 1,080,953 | SEC↗ |
| Evans John M. | CEO | S Sale | 2022-10-31 | 2022-11-02 | 2,909 | $47.89 | $139.3K | 1,058,520 | SEC↗ |
| Evans John M. | CEO | S Sale | 2022-10-31 | 2022-11-02 | 5,008 | $44.93 | $225.0K | 117,992 | SEC↗ |
| Evans John M. | CEO | S Sale | 2022-10-31 | 2022-11-02 | 4,569 | $46.19 | $211.0K | 113,423 | SEC↗ |
| Evans John M. | CEO | S Sale | 2022-10-31 | 2022-11-02 | 8,235 | $46.91 | $386.3K | 105,188 | SEC↗ |
| Evans John M. | CEO | S Sale | 2022-10-31 | 2022-11-02 | 2,188 | $47.91 | $104.8K | 103,000 | SEC↗ |
| Evans John M. | CEO | S Sale | 2022-10-31 | 2022-11-02 | 11,756 | $46.88 | $551.1K | 1,061,429 | SEC↗ |
| FMR LLC | 10% Owner | J Other | 2022-09-06 | 2022-09-08 | 25,620 | — | $0 | 0 | SEC↗ |
| FMR LLC | 10% Owner | S Sale | 2022-09-06 | 2022-09-08 | 551 | $54.25 | $29.9K | 0 | SEC↗ |
| FMR LLC | 10% Owner | J Other | 2022-09-06 | 2022-09-08 | 551 | — | $0 | 551 | SEC↗ |
| Walsh Kathleen E | Director | A Award deriv | 2022-09-01 | 2022-09-02 | 10,391 | — | $0 | 10,391 | SEC↗ |
| Fishman Mark | Director | A Award deriv | 2022-09-01 | 2022-09-02 | 10,391 | — | $0 | 10,391 | SEC↗ |
| MARAGANORE JOHN | Director | A Award deriv | 2022-09-01 | 2022-09-02 | 10,391 | — | $0 | 10,391 | SEC↗ |
| COOPER GRAHAM K | Director | A Award deriv | 2022-09-01 | 2022-09-02 | 10,391 | — | $0 | 10,391 | SEC↗ |
| Burow Kristina | Director | A Award deriv | 2022-09-01 | 2022-09-02 | 10,391 | — | $0 | 10,391 | SEC↗ |
| Ho Carole | Director | A Award deriv | 2022-09-01 | 2022-09-02 | 10,391 | — | $0 | 10,391 | SEC↗ |
| FMR LLC | 10% Owner | S Sale | 2022-08-05 | 2022-08-08 | 167 | $61.00 | $10.2K | 0 | SEC↗ |
| FMR LLC | 10% Owner | S Sale | 2022-08-05 | 2022-08-08 | 20,159 | $60.50 | $1.22M | 0 | SEC↗ |
| FMR LLC | 10% Owner | J Other | 2022-08-04 | 2022-08-08 | 180,366 | — | $0 | 193,184 | SEC↗ |
| FMR LLC | 10% Owner | J Other | 2022-08-04 | 2022-08-08 | 800,000 | — | $0 | 2,135,511 | SEC↗ |
| FMR LLC | 10% Owner | J Other | 2022-08-04 | 2022-08-08 | 375,536 | — | $0 | 375,536 | SEC↗ |
| FMR LLC | 10% Owner | J Other | 2022-08-04 | 2022-08-08 | 312,512 | — | $0 | 2,803,027 | SEC↗ |
| FMR LLC | 10% Owner | J Other | 2022-08-04 | 2022-08-08 | 20,159 | — | $0 | 20,159 | SEC↗ |
| FMR LLC | 10% Owner | J Other | 2022-08-04 | 2022-08-08 | 167,564 | — | $0 | 25,620 | SEC↗ |
| FMR LLC | 10% Owner | J Other | 2022-08-04 | 2022-08-08 | 375,369 | — | $0 | 167 | SEC↗ |
| Evans John M. | CEO | S Sale | 2022-07-28 | 2022-07-29 | 10,181 | $64.87 | $660.4K | 1,108,339 | SEC↗ |
| Evans John M. | CEO | S Sale | 2022-07-28 | 2022-07-29 | 15,236 | $65.82 | $1.00M | 1,093,103 | SEC↗ |