Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$0
Insiders on file
20
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Brun Scott C. | Director | 12 | $0 | $0 | 2026-06-09 |
| Bollard Catherine | Director | 16 | $11.0K | $0 | 2026-06-09 |
| Tomasello Shawn | Director | 9 | $50.2K | $0 | 2026-06-09 |
| Simon Mark | Director | 19 | $147.7K | $0 | 2026-06-09 |
| HENRIQUES RICHARD C JR | Director | 14 | $0 | $0 | 2026-06-09 |
| Das Arun | Chief Business Officer | 15 | $0 | $0 | 2026-03-02 |
| Gerard Michael | General Counsel | 15 | $15.0K | $0 | 2026-03-02 |
| Binder Gwendolyn | See Remarks | 55 | $44.6K | $1.69M | 2026-03-02 |
| Chang David J. | Chief Medical Officer | 23 | $19.9K | $0 | 2026-03-02 |
| Marda Anup | Chief Financial Officer | 23 | $49.5K | $0 | 2026-03-02 |
| Nichtberger Steven | President & CEO | 28 | $251.4K | $0 | 2026-03-02 |
| Gavel Steve | Chief Commercial Officer | 2 | $50.3K | $0 | 2026-01-21 |
| 5AM Partners V, LLC | 10% Owner | 2 | $0 | $3.83M | 2021-11-01 |
| 5AM Ventures V, L.P. | 10% Owner | 1 | $0 | $6.06M | 2021-09-07 |
| DANIELS BRIAN | Director | 3 | $0 | $0 | 2021-06-01 |
| Stalter John Brian | General Counsel | 2 | $0 | $0 | 2021-03-01 |
| ROCKLAGE SCOTT M | 10% Owner | 4 | $0 | $5.03M | 2021-01-12 |
| Schwab Andrew J. | 10% Owner | 6 | $5.00M | $4.40M | 2020-12-10 |
| Green Jeremy | 10% Owner | 2 | $0 | $0 | 2019-10-29 |
| DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 10% Owner | 5 | $7.70M | $0 | 2019-10-29 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Brun Scott C. | Director | A Award deriv | 2026-06-09 | 2026-06-10 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Bollard Catherine | Director | A Award deriv | 2026-06-09 | 2026-06-10 | 22,000 | — | $0 | 22,000 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | A Award deriv | 2026-06-09 | 2026-06-10 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Simon Mark | Director | A Award deriv | 2026-06-09 | 2026-06-10 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Tomasello Shawn | Director | A Award deriv | 2026-06-09 | 2026-06-10 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2026-03-02 | 2026-03-02 | 225,000 | — | $0 | 225,000 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2026-03-02 | 2026-03-02 | 674,000 | — | $0 | 674,000 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2026-03-02 | 2026-03-02 | 225,000 | — | $0 | 225,000 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | A Award deriv | 2026-03-02 | 2026-03-02 | 225,000 | — | $0 | 225,000 | SEC↗ |
| Gerard Michael | General Counsel | A Award deriv | 2026-03-02 | 2026-03-02 | 175,000 | — | $0 | 175,000 | SEC↗ |
| Das Arun | Chief Business Officer | A Award deriv | 2026-03-02 | 2026-03-02 | 175,000 | — | $0 | 175,000 | SEC↗ |
| Gerard Michael | General Counsel | P Buy | 2026-01-21 | 2026-01-21 | 6,600 | $2.27 | $15.0K | 6,600 | SEC↗ |
| Simon Mark | Director | P Buy | 2026-01-21 | 2026-01-21 | 11,061 | $2.28 | $25.2K | 147,205 | SEC↗ |
| Nichtberger Steven | President & CEO | P Buy | 2026-01-21 | 2026-01-21 | 45,000 | $2.24 | $100.8K | 1,031,483 | SEC↗ |
| Bollard Catherine | Director | P Buy | 2026-01-21 | 2026-01-21 | 4,405 | $2.27 | $10.0K | 5,405 | SEC↗ |
| Gavel Steve | Chief Commercial Officer | P Buy | 2026-01-21 | 2026-01-21 | 22,170 | $2.27 | $50.3K | 22,170 | SEC↗ |
| Tomasello Shawn | Director | P Buy | 2026-01-21 | 2026-01-21 | 22,725 | $2.21 | $50.2K | 22,725 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | P Buy | 2026-01-21 | 2026-01-21 | 11,312 | $2.19 | $24.8K | 31,312 | SEC↗ |
| Chang David J. | Chief Medical Officer | P Buy | 2026-01-21 | 2026-01-21 | 8,800 | $2.26 | $19.9K | 8,800 | SEC↗ |
| Gavel Steve | CHIEF COMMERCIAL OFFICER | A Award deriv | 2025-10-13 | 2025-10-15 | 275,000 | — | $0 | 275,000 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | A Award deriv | 2025-06-09 | 2025-06-09 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Tomasello Shawn | Director | A Award deriv | 2025-06-09 | 2025-06-09 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Bollard Catherine | Director | A Award deriv | 2025-06-09 | 2025-06-09 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Brun Scott C. | Director | A Award deriv | 2025-06-09 | 2025-06-09 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Simon Mark | Director | A Award deriv | 2025-06-09 | 2025-06-09 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Chang David J. | Chief Medical Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 113,500 | — | $0 | 0 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 113,500 | — | $0 | 113,500 | SEC↗ |
| Chang David J. | Chief Medical Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 135,000 | — | $0 | 0 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 135,000 | — | $0 | 135,000 | SEC↗ |
| Chang David J. | Chief Medical Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 150,000 | — | $0 | 0 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 150,000 | — | $0 | 150,000 | SEC↗ |
| Chang David J. | Chief Medical Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 130,000 | — | $0 | 0 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Chang David J. | Chief Medical Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 185,709 | — | $0 | 0 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 185,709 | — | $0 | 185,709 | SEC↗ |
| Chang David J. | Chief Medical Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 48,836 | — | $0 | 0 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 48,836 | — | $0 | 48,836 | SEC↗ |
| Chang David J. | Chief Medical Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 38,238 | — | $0 | 0 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 38,238 | — | $0 | 38,238 | SEC↗ |
| Bollard Catherine | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 46,428 | — | $0 | 46,428 | SEC↗ |
| Bollard Catherine | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 46,428 | — | $0 | 0 | SEC↗ |
| Bollard Catherine | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Bollard Catherine | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 0 | SEC↗ |
| Bollard Catherine | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 0 | SEC↗ |
| Bollard Catherine | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Bollard Catherine | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Bollard Catherine | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 0 | SEC↗ |
| Das Arun | Chief Business Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Das Arun | Chief Business Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 35,000 | — | $0 | 35,000 | SEC↗ |
| Das Arun | Chief Business Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 100,000 | — | $0 | 0 | SEC↗ |
| Das Arun | Chief Business Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 18,416 | — | $0 | 18,416 | SEC↗ |
| Das Arun | Chief Business Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 18,416 | — | $0 | 0 | SEC↗ |
| Das Arun | Chief Business Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 35,000 | — | $0 | 0 | SEC↗ |
| Das Arun | Chief Business Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 100,000 | — | $0 | 0 | SEC↗ |
| Das Arun | Chief Business Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 150,000 | — | $0 | 150,000 | SEC↗ |
| Das Arun | Chief Business Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 150,000 | — | $0 | 0 | SEC↗ |
| Das Arun | Chief Business Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | A Award deriv | 2025-05-19 | 2025-05-19 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | D To issuer deriv | 2025-05-19 | 2025-05-19 | 130,000 | — | $0 | 0 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | A Award deriv | 2025-05-19 | 2025-05-19 | 176,000 | — | $0 | 176,000 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | D To issuer deriv | 2025-05-19 | 2025-05-19 | 176,000 | — | $0 | 0 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | A Award deriv | 2025-05-19 | 2025-05-19 | 160,000 | — | $0 | 160,000 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | D To issuer deriv | 2025-05-19 | 2025-05-19 | 160,000 | — | $0 | 0 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | A Award deriv | 2025-05-19 | 2025-05-19 | 125,000 | — | $0 | 125,000 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | D To issuer deriv | 2025-05-19 | 2025-05-19 | 125,000 | — | $0 | 0 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | A Award deriv | 2025-05-19 | 2025-05-19 | 29,908 | — | $0 | 29,908 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | D To issuer deriv | 2025-05-19 | 2025-05-19 | 29,908 | — | $0 | 0 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | A Award deriv | 2025-05-19 | 2025-05-19 | 66,667 | — | $0 | 66,667 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | D To issuer deriv | 2025-05-19 | 2025-05-19 | 66,667 | — | $0 | 0 | SEC↗ |
| Simon Mark | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 0 | SEC↗ |
| Simon Mark | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Simon Mark | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 18,460 | — | $0 | 0 | SEC↗ |
| Simon Mark | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 18,460 | — | $0 | 18,460 | SEC↗ |
| Simon Mark | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 0 | SEC↗ |
| Simon Mark | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Simon Mark | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 0 | SEC↗ |
| Simon Mark | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Marda Anup | Chief Financial Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 66,463 | — | $0 | 0 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 139,282 | — | $0 | 139,282 | SEC↗ |
| Marda Anup | Chief Financial Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 139,282 | — | $0 | 0 | SEC↗ |
| Marda Anup | Chief Financial Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 150,000 | — | $0 | 0 | SEC↗ |
| Marda Anup | Chief Financial Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 130,000 | — | $0 | 0 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 150,000 | — | $0 | 150,000 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 66,463 | — | $0 | 66,463 | SEC↗ |
| Marda Anup | Chief Financial Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 24,711 | — | $0 | 0 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 24,711 | — | $0 | 24,711 | SEC↗ |
| Marda Anup | Chief Financial Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 100,000 | — | $0 | 0 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Marda Anup | Chief Financial Officer | D To issuer deriv | 2025-05-19 | 2025-05-19 | 135,000 | — | $0 | 0 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 135,000 | — | $0 | 135,000 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2025-05-19 | 2025-05-19 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Tomasello Shawn | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 44,000 | — | $0 | 44,000 | SEC↗ |
| Tomasello Shawn | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 0 | SEC↗ |
| Tomasello Shawn | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Tomasello Shawn | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 44,000 | — | $0 | 0 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 22,000 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 22,000 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 46,428 | — | $0 | 0 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 46,428 | — | $0 | 46,428 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 0 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 22,000 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 0 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 0 | SEC↗ |
| Gerard Michael | General Counsel | D To issuer deriv | 2025-05-19 | 2025-05-19 | 75,000 | — | $0 | 0 | SEC↗ |
| Gerard Michael | General Counsel | A Award deriv | 2025-05-19 | 2025-05-19 | 75,000 | — | $0 | 75,000 | SEC↗ |
| Gerard Michael | General Counsel | D To issuer deriv | 2025-05-19 | 2025-05-19 | 112,500 | — | $0 | 0 | SEC↗ |
| Gerard Michael | General Counsel | A Award deriv | 2025-05-19 | 2025-05-19 | 112,500 | — | $0 | 112,500 | SEC↗ |
| Gerard Michael | General Counsel | D To issuer deriv | 2025-05-19 | 2025-05-19 | 100,000 | — | $0 | 0 | SEC↗ |
| Gerard Michael | General Counsel | A Award deriv | 2025-05-19 | 2025-05-19 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Gerard Michael | General Counsel | A Award deriv | 2025-05-19 | 2025-05-19 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Gerard Michael | General Counsel | D To issuer deriv | 2025-05-19 | 2025-05-19 | 100,000 | — | $0 | 0 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2025-05-19 | 2025-05-19 | 300,000 | — | $0 | 300,000 | SEC↗ |
| Nichtberger Steven | President & CEO | D To issuer deriv | 2025-05-19 | 2025-05-19 | 99,714 | — | $0 | 0 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2025-05-19 | 2025-05-19 | 99,714 | — | $0 | 99,714 | SEC↗ |
| Nichtberger Steven | President & CEO | D To issuer deriv | 2025-05-19 | 2025-05-19 | 300,000 | — | $0 | 0 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2025-05-19 | 2025-05-19 | 353,000 | — | $0 | 353,000 | SEC↗ |
| Nichtberger Steven | President & CEO | D To issuer deriv | 2025-05-19 | 2025-05-19 | 333,500 | — | $0 | 0 | SEC↗ |
| Nichtberger Steven | President & CEO | D To issuer deriv | 2025-05-19 | 2025-05-19 | 353,000 | — | $0 | 0 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2025-05-19 | 2025-05-19 | 411,600 | — | $0 | 411,600 | SEC↗ |
| Nichtberger Steven | President & CEO | D To issuer deriv | 2025-05-19 | 2025-05-19 | 411,600 | — | $0 | 0 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2025-05-19 | 2025-05-19 | 380,000 | — | $0 | 380,000 | SEC↗ |
| Nichtberger Steven | President & CEO | D To issuer deriv | 2025-05-19 | 2025-05-19 | 380,000 | — | $0 | 0 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2025-05-19 | 2025-05-19 | 333,500 | — | $0 | 333,500 | SEC↗ |
| Brun Scott C. | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 0 | SEC↗ |
| Brun Scott C. | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 0 | SEC↗ |
| Brun Scott C. | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Brun Scott C. | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Brun Scott C. | Director | A Award deriv | 2025-05-19 | 2025-05-19 | 44,000 | — | $0 | 44,000 | SEC↗ |
| Brun Scott C. | Director | D To issuer deriv | 2025-05-19 | 2025-05-19 | 44,000 | — | $0 | 0 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2025-03-03 | 2025-03-04 | 450,000 | — | $0 | 450,000 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2025-03-03 | 2025-03-04 | 145,000 | — | $0 | 145,000 | SEC↗ |
| Das Arun | Chief Business Officer | A Award deriv | 2025-03-03 | 2025-03-04 | 115,000 | — | $0 | 115,000 | SEC↗ |
| Gerard Michael | General Counsel | A Award deriv | 2025-03-03 | 2025-03-04 | 115,000 | — | $0 | 115,000 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2025-03-03 | 2025-03-04 | 145,000 | — | $0 | 145,000 | SEC↗ |
| Binder Gwendolyn | President, Science & Tech. | A Award deriv | 2025-03-03 | 2025-03-04 | 145,000 | — | $0 | 145,000 | SEC↗ |
| Tomasello Shawn | Director | A Award deriv | 2024-06-03 | 2024-06-04 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Brun Scott C. | Director | A Award deriv | 2024-06-03 | 2024-06-04 | 22,000 | — | $0 | 22,000 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | A Award deriv | 2024-06-03 | 2024-06-04 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Simon Mark | Director | A Award deriv | 2024-06-03 | 2024-06-04 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Bollard Catherine | Director | A Award deriv | 2024-06-03 | 2024-06-04 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | A Award deriv | 2024-03-01 | 2024-03-04 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Das Arun | Chief Business Officer | A Award deriv | 2024-03-01 | 2024-03-04 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2024-03-01 | 2024-03-04 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2024-03-01 | 2024-03-04 | 353,000 | — | $0 | 353,000 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2024-03-01 | 2024-03-04 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Gerard Michael | General Counsel | A Award deriv | 2024-03-01 | 2024-03-04 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise deriv | 2024-01-19 | 2024-01-19 | 11,000 | — | $0 | 100,756 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2024-01-19 | 2024-01-19 | 700 | $20.33 | $14.2K | 20,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2024-01-19 | 2024-01-19 | 10,300 | $19.54 | $201.3K | 20,700 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise | 2024-01-19 | 2024-01-19 | 11,000 | $1.01 | $11.1K | 31,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise deriv | 2023-12-19 | 2023-12-19 | 11,000 | — | $0 | 111,756 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise | 2023-12-19 | 2023-12-19 | 11,000 | $1.01 | $11.1K | 31,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-12-19 | 2023-12-19 | 7,868 | $21.76 | $171.2K | 23,132 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-12-19 | 2023-12-19 | 3,132 | $22.22 | $69.6K | 20,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise deriv | 2023-11-20 | 2023-11-21 | 11,000 | — | $0 | 122,756 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-11-20 | 2023-11-21 | 7,458 | $18.02 | $134.4K | 20,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise | 2023-11-20 | 2023-11-21 | 11,000 | $1.01 | $11.1K | 31,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-11-20 | 2023-11-21 | 3,542 | $17.39 | $61.6K | 27,458 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise deriv | 2023-10-19 | 2023-10-19 | 11,000 | — | $0 | 133,756 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-10-19 | 2023-10-19 | 408 | $14.28 | $5.8K | 20,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-10-19 | 2023-10-19 | 10,592 | $13.32 | $141.1K | 20,408 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise | 2023-10-19 | 2023-10-19 | 11,000 | $1.01 | $11.1K | 31,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise deriv | 2023-09-19 | 2023-09-20 | 11,000 | — | $0 | 144,756 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-09-19 | 2023-09-20 | 10,300 | $17.50 | $180.3K | 20,700 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise | 2023-09-19 | 2023-09-20 | 11,000 | $1.01 | $11.1K | 31,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-09-19 | 2023-09-20 | 700 | $18.50 | $12.9K | 20,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise deriv | 2023-08-21 | 2023-08-22 | 11,000 | — | $0 | 155,756 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-08-21 | 2023-08-22 | 300 | $13.82 | $4.1K | 20,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise | 2023-08-21 | 2023-08-22 | 11,000 | $1.01 | $11.1K | 31,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-08-21 | 2023-08-22 | 10,700 | $13.41 | $143.5K | 20,300 | SEC↗ |
| Tomasello Shawn | Director | A Award deriv | 2023-07-21 | 2023-07-24 | 44,000 | — | $0 | 44,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise deriv | 2023-07-19 | 2023-07-19 | 11,000 | — | $0 | 166,756 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise | 2023-07-19 | 2023-07-19 | 11,000 | $1.01 | $11.1K | 31,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-07-19 | 2023-07-19 | 8,185 | $13.67 | $111.9K | 22,815 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-07-19 | 2023-07-19 | 2,815 | $14.26 | $40.1K | 20,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise deriv | 2023-06-20 | 2023-06-21 | 11,000 | — | $0 | 177,756 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-06-20 | 2023-06-21 | 11,000 | $12.99 | $142.9K | 20,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise | 2023-06-20 | 2023-06-21 | 11,000 | $1.01 | $11.1K | 31,000 | SEC↗ |
| Brun Scott C. | Director | A Award deriv | 2023-06-01 | 2023-06-02 | 22,000 | — | $0 | 22,000 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | A Award deriv | 2023-06-01 | 2023-06-02 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Bollard Catherine | Director | A Award deriv | 2023-06-01 | 2023-06-02 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Simon Mark | Director | A Award deriv | 2023-06-01 | 2023-06-02 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise deriv | 2023-05-19 | 2023-05-19 | 22,000 | — | $0 | 188,756 | SEC↗ |
| Binder Gwendolyn | See Remarks | S Sale | 2023-05-19 | 2023-05-19 | 22,000 | $11.81 | $259.8K | 20,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | M Exercise | 2023-05-19 | 2023-05-19 | 22,000 | $1.01 | $22.2K | 42,000 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2023-01-18 | 2023-01-27 | 150,000 | — | $0 | 150,000 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2023-01-18 | 2023-01-27 | 150,000 | — | $0 | 150,000 | SEC↗ |
| Binder Gwendolyn | See Remarks | A Award deriv | 2023-01-18 | 2023-01-27 | 176,000 | — | $0 | 176,000 | SEC↗ |
| Das Arun | Chief Business Officer | A Award deriv | 2023-01-18 | 2023-01-27 | 150,000 | — | $0 | 150,000 | SEC↗ |
| Gerard Michael | General Counsel | A Award deriv | 2023-01-18 | 2023-01-27 | 112,500 | — | $0 | 112,500 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2023-01-18 | 2023-01-27 | 411,600 | — | $0 | 411,600 | SEC↗ |
| Nichtberger Steven | President & CEO | P Buy | 2022-10-19 | 2022-10-19 | 8,127 | $1.25 | $10.2K | 986,483 | SEC↗ |
| Nichtberger Steven | President & CEO | P Buy | 2022-10-18 | 2022-10-18 | 141,873 | $0.99 | $140.5K | 978,356 | SEC↗ |
| Binder Gwendolyn | See Remarks | P Buy | 2022-10-18 | 2022-10-18 | 20,000 | $0.99 | $19.8K | 20,000 | SEC↗ |
| Simon Mark | Director | P Buy | 2022-10-18 | 2022-10-18 | 7,000 | $0.98 | $6.9K | 7,000 | SEC↗ |
| Simon Mark | Director | P Buy | 2022-10-18 | 2022-10-18 | 118,000 | $0.98 | $115.6K | 136,144 | SEC↗ |
| Marda Anup | Chief Financial Officer | P Buy | 2022-10-18 | 2022-10-18 | 50,000 | $0.99 | $49.5K | 50,000 | SEC↗ |
| Bollard Catherine | Director | P Buy | 2022-10-18 | 2022-10-18 | 1,000 | $0.99 | $990 | 1,000 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | A Award deriv | 2022-06-01 | 2022-06-03 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Bollard Catherine | Director | A Award deriv | 2022-06-01 | 2022-06-03 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Simon Mark | Director | A Award deriv | 2022-06-01 | 2022-06-03 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Brun Scott C. | Director | A Award deriv | 2022-06-01 | 2022-06-03 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Nichtberger Steven | President & CEO | M Exercise deriv | 2022-01-31 | 2022-02-02 | 50,000 | — | $0 | 229,677 | SEC↗ |
| Nichtberger Steven | President & CEO | M Exercise | 2022-01-31 | 2022-02-02 | 50,000 | $1.01 | $50.5K | 836,483 | SEC↗ |
| Binder Gwendolyn | See Remarks | A Award deriv | 2022-01-18 | 2022-01-19 | 160,000 | — | $0 | 160,000 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2022-01-18 | 2022-01-19 | 380,000 | — | $0 | 380,000 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2022-01-18 | 2022-01-19 | 135,000 | — | $0 | 135,000 | SEC↗ |
| Das Arun | Chief Business Officer | A Award deriv | 2022-01-18 | 2022-01-19 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Gerard Michael | General Counsel | A Award deriv | 2022-01-18 | 2022-01-19 | 75,000 | — | $0 | 75,000 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2022-01-18 | 2022-01-19 | 135,000 | — | $0 | 135,000 | SEC↗ |
| 5AM Partners V, LLC | 10% Owner | S Sale | 2021-11-01 | 2021-11-03 | 36,544 | $13.00 | $475.1K | 333,144 | SEC↗ |
| 5AM Partners V, LLC | 10% Owner | S Sale | 2021-11-01 | 2021-11-03 | 258,456 | $13.00 | $3.36M | 1,731,119 | SEC↗ |
| 5AM Ventures V, L.P. | 10% Owner | S Sale | 2021-09-07 | 2021-09-09 | 625,000 | $9.70 | $6.06M | 1,989,575 | SEC↗ |
| Gerard Michael | General Counsel | A Award deriv | 2021-09-01 | 2021-09-03 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Brun Scott C. | Director | A Award deriv | 2021-06-24 | 2021-06-28 | 44,000 | — | $0 | 44,000 | SEC↗ |
| DANIELS BRIAN | Director | A Award deriv | 2021-06-01 | 2021-06-03 | 22,000 | — | $0 | 22,000 | SEC↗ |
| HENRIQUES RICHARD C JR | Director | A Award deriv | 2021-06-01 | 2021-06-03 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Bollard Catherine | Director | A Award deriv | 2021-06-01 | 2021-06-03 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Simon Mark | Director | A Award deriv | 2021-06-01 | 2021-06-03 | 22,000 | — | $0 | 22,000 | SEC↗ |
| DANIELS BRIAN | Director | A Award deriv | 2021-06-01 | 2021-06-28 | 22,000 | — | $0 | 0 | SEC↗ |
| Binder Gwendolyn | EVP, Science & Technology | A Award deriv | 2021-03-01 | 2021-03-02 | 125,000 | — | $0 | 125,000 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2021-03-01 | 2021-03-02 | 113,500 | — | $0 | 113,500 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2021-03-01 | 2021-03-02 | 333,500 | — | $0 | 333,500 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2021-03-01 | 2021-03-02 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Stalter John Brian | General Counsel | A Award deriv | 2021-03-01 | 2021-03-02 | 64,500 | — | $0 | 64,500 | SEC↗ |
| ROCKLAGE SCOTT M | 10% Owner | S Sale | 2021-01-12 | 2021-01-12 | 74,470 | $13.00 | $968.1K | 2,614,575 | SEC↗ |
| ROCKLAGE SCOTT M | 10% Owner | S Sale | 2021-01-12 | 2021-01-12 | 10,530 | $13.00 | $136.9K | 369,688 | SEC↗ |
| ROCKLAGE SCOTT M | 10% Owner | S Sale | 2021-01-08 | 2021-01-12 | 37,411 | $13.00 | $486.3K | 380,218 | SEC↗ |
| ROCKLAGE SCOTT M | 10% Owner | S Sale | 2021-01-08 | 2021-01-12 | 264,589 | $13.00 | $3.44M | 2,689,045 | SEC↗ |
| Schwab Andrew J. | 10% Owner | S Sale | 2020-12-10 | 2020-12-14 | 36,916 | $14.75 | $544.5K | 417,629 | SEC↗ |
| Schwab Andrew J. | 10% Owner | S Sale | 2020-12-10 | 2020-12-14 | 261,084 | $14.75 | $3.85M | 2,953,634 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2020-12-08 | 2020-12-09 | 93,226 | — | $0 | 93,226 | SEC↗ |
| Stalter John Brian | General Counsel | A Award deriv | 2020-09-14 | 2020-09-16 | 60,000 | — | $0 | 60,000 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2020-03-01 | 2020-03-03 | 24,711 | — | $0 | 24,711 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2020-03-01 | 2020-03-03 | 38,238 | — | $0 | 38,238 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2020-03-01 | 2020-03-03 | 300,000 | — | $0 | 300,000 | SEC↗ |
| DANIELS BRIAN | Director | A Award deriv | 2020-02-11 | 2020-02-13 | 44,000 | — | $0 | 44,000 | SEC↗ |
| Green Jeremy | 10% Owner | C Conversion deriv | 2019-10-29 | 2019-10-29 | 1,044,568 | — | $0 | 0 | SEC↗ |
| Nichtberger Steven | President & CEO | C Conversion deriv | 2019-10-29 | 2019-10-30 | 90,725 | — | $0 | 0 | SEC↗ |
| Simon Mark | Director | C Conversion deriv | 2019-10-29 | 2019-10-30 | 27,217 | — | $0 | 0 | SEC↗ |
| DEERFIELD MANAGEMENT COMPANY, | 10% Owner | C Conversion deriv | 2019-10-29 | 2019-10-30 | 696,379 | — | $0 | 0 | SEC↗ |
| DEERFIELD MANAGEMENT COMPANY, | 10% Owner | C Conversion deriv | 2019-10-29 | 2019-10-30 | 696,379 | — | $0 | 0 | SEC↗ |
| Schwab Andrew J. | 10% Owner | C Conversion deriv | 2019-10-29 | 2019-10-31 | 1,675,532 | — | $0 | 0 | SEC↗ |
| Schwab Andrew J. | 10% Owner | C Conversion deriv | 2019-10-29 | 2019-10-31 | 3,146,551 | — | $0 | 0 | SEC↗ |
| Green Jeremy | 10% Owner | C Conversion | 2019-10-29 | 2019-10-29 | 696,378 | — | $0 | 696,378 | SEC↗ |
| Nichtberger Steven | President & CEO | C Conversion | 2019-10-29 | 2019-10-30 | 60,483 | — | $0 | 786,483 | SEC↗ |
| Simon Mark | Director | C Conversion | 2019-10-29 | 2019-10-30 | 18,144 | — | $0 | 18,144 | SEC↗ |
| DEERFIELD MANAGEMENT COMPANY, | 10% Owner | P Buy | 2019-10-29 | 2019-10-30 | 700,000 | $11.00 | $7.70M | 700,000 | SEC↗ |
| DEERFIELD MANAGEMENT COMPANY, | 10% Owner | C Conversion | 2019-10-29 | 2019-10-30 | 464,253 | — | $0 | 464,253 | SEC↗ |
| DEERFIELD MANAGEMENT COMPANY, | 10% Owner | C Conversion | 2019-10-29 | 2019-10-30 | 464,253 | — | $0 | 464,253 | SEC↗ |
| Schwab Andrew J. | 10% Owner | P Buy | 2019-10-29 | 2019-10-31 | 454,545 | $11.00 | $5.00M | 454,545 | SEC↗ |
| Schwab Andrew J. | 10% Owner | C Conversion | 2019-10-29 | 2019-10-31 | 3,214,721 | — | $0 | 3,214,721 | SEC↗ |
| Chang David J. | Chief Medical Officer | A Award deriv | 2019-10-24 | 2019-10-28 | 48,836 | — | $0 | 48,836 | SEC↗ |
| Nichtberger Steven | President & CEO | A Award deriv | 2019-10-24 | 2019-10-28 | 99,714 | — | $0 | 99,714 | SEC↗ |
| Marda Anup | Chief Financial Officer | A Award deriv | 2019-10-24 | 2019-10-28 | 66,463 | — | $0 | 66,463 | SEC↗ |
| Binder Gwendolyn | EVP, Science & Technology | A Award deriv | 2019-10-24 | 2019-10-28 | 29,908 | — | $0 | 29,908 | SEC↗ |