CBIO

CRESCENT BIOPHARMA, INC.CIK 1253689 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

—

0 trades · 0 insiders

Open-mkt sales · 90d

$571.0K

18 trades · 7 insiders

Net · 90d

$-571.0K

Insiders on file

AI insights for CBIO PRO

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AI insights for CBIO

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date

Insiders

Insider	Role	Trades	Bought	Sold	Last trade
McNeill Jonathan	President and COO	9	$0	$524.1K	2026-09-18
Brumm Joshua T	Chief Executive Officer, Director	9	$0	$1.08M	2026-09-18
Pinkas Jan	Chief Scientific Officer	7	$0	$46.7K	2026-09-16
Bispham Barbara Harlin	See Remarks	6	$0	$44.1K	2026-09-16
Im Ellie Eunkyung	Chief Medical Officer	6	$0	$44.2K	2026-09-16
Scalzo Richard William	Chief Financial Officer	6	$0	$40.3K	2026-09-16
Lynch Ryan	See Remarks	6	$0	$17.0K	2026-09-16
Fairmount Healthcare Fund II L.P.	Director, 10% Owner	2	$20.00M	$0	2026-07-16
Balcom Alexandra	Director	2	$0	$0	2026-06-02
Moran Susan	Director	2	$0	$0	2026-06-02
Violin Jonathan	Director	2	$0	$0	2026-06-02
Harwin Peter Evan	Director, 10% Owner	4	$20.00M	$0	2026-06-02
Lubner David Charles	Director	2	$0	$0	2026-06-02
Doughty Christopher Grant	Chief Business Officer	3	$0	$0	2025-12-15
BVF GP HOLDINGS LLC	10% Owner	6	$0	$0	2025-06-13
GNI Hong Kong Ltd	10% Owner	4	$0	$0	2023-10-27
Miller Seline E.	SVP Finance; Interim CFO & PAO	4	$3.0K	$0	2023-08-31
Hunt Andrea	Director	19	$0	$0	2023-08-31
LAWLOR AUGUSTINE	Director	28	$0	$423.3K	2023-08-31
USMAN NASSIM	President and CEO	43	$35.4K	$0	2023-08-31
Blouse Grant E.	Chief Scientific Officer	4	$7.2K	$0	2022-08-09
Ling Geoffrey M.D.	Director	12	$18.7K	$0	2022-01-07
Williams Eddie	Director	19	$11.6K	$0	2022-01-07
DESOUZA ERROL B	Director	23	$0	$0	2021-10-01
JEW JEANNE Y	Director	1	$0	$0	2021-09-09
Levy Howard	Chief Medical Officer	26	$29.0K	$1.9K	2021-08-09
TETLOW SHARON	Director	5	$0	$0	2021-06-09
Musil Clinton	Chief Financial Officer	3	$0	$0	2021-02-08
Cai Veronica	Controller	4	$8.2K	$0	2020-03-13
Richard John P	Director	11	$18.0K	$0	2020-03-13
Payne Fletcher	Chief Financial Officer	18	$20.0K	$0	2019-08-12
HILL STEPHEN A	Director	11	$10.1K	$0	2018-09-06
Deerfield Mgmt L.P.	10% Owner	10	$0	$2.19M	2018-03-08
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	10% Owner	5	$0	$2.19M	2018-03-08
SELICK HAROLD E	Director	19	$0	$0	2018-01-16
Madison Edwin	Chief Scientific Officer	9	$0	$0	2015-10-22
Himawan Jeff	Director, 10% Owner	12	$0	$0	2015-08-20

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
McNeill Jonathan	President and COO	S Sale	2026-09-18	2026-09-18	3,839	$16.71	$64.1K	134,588	SEC↗
Brumm Joshua T	Chief Executive Officer	S Sale	2026-09-18	2026-09-18	7,837	$16.71	$131.0K	271,765	SEC↗
McNeill Jonathan	President and COO	S Sale	2026-09-18	2026-09-18	3,839	$16.71	$64.1K	134,588	SEC↗
Brumm Joshua T	Chief Executive Officer, Dir	S Sale	2026-09-18	2026-09-18	7,837	$16.71	$131.0K	271,765	SEC↗
McNeill Jonathan	President and COO	S Sale	2026-09-16	2026-09-18	731	$17.90	$13.1K	138,427	SEC↗
Brumm Joshua T	Chief Executive Officer	S Sale	2026-09-16	2026-09-18	1,610	$17.90	$28.8K	279,602	SEC↗
Bispham Barbara Harlin	See Remarks	S Sale	2026-09-16	2026-09-18	620	$17.90	$11.1K	18,710	SEC↗
Scalzo Richard William	Chief Financial Officer	S Sale	2026-09-16	2026-09-18	568	$17.90	$10.2K	19,730	SEC↗
Im Ellie Eunkyung	Chief Medical Officer	S Sale	2026-09-16	2026-09-18	623	$17.90	$11.2K	21,446	SEC↗
Pinkas Jan	Chief Scientific Officer	S Sale	2026-09-16	2026-09-18	658	$17.90	$11.8K	21,581	SEC↗
Lynch Ryan	See Remarks	S Sale	2026-09-16	2026-09-18	240	$17.90	$4.3K	13,631	SEC↗
Lynch Ryan	See Remarks	S Sale	2026-09-16	2026-09-18	240	$17.90	$4.3K	13,631	SEC↗
Pinkas Jan	Chief Scientific Officer	S Sale	2026-09-16	2026-09-18	658	$17.90	$11.8K	21,581	SEC↗
Im Ellie Eunkyung	Chief Medical Officer	S Sale	2026-09-16	2026-09-18	623	$17.90	$11.2K	21,446	SEC↗
Scalzo Richard William	Chief Financial Officer	S Sale	2026-09-16	2026-09-18	568	$17.90	$10.2K	19,730	SEC↗
McNeill Jonathan	President and COO	S Sale	2026-09-16	2026-09-18	731	$17.90	$13.1K	138,427	SEC↗
Brumm Joshua T	Chief Executive Officer, Dir	S Sale	2026-09-16	2026-09-18	1,610	$17.90	$28.8K	279,602	SEC↗
Bispham Barbara Harlin	See Remarks	S Sale	2026-09-16	2026-09-18	620	$17.90	$11.1K	18,710	SEC↗
Fairmount Healthcare Fund II L	Director, 10% Owner	P Buy deriv	2026-07-16	2026-07-20	525,897	$14.50	$7.63M	2,294,037	SEC↗
Fairmount Healthcare Fund II L	Director, 10% Owner	P Buy	2026-07-16	2026-07-20	853,450	$14.50	$12.38M	3,601,316	SEC↗
Brumm Joshua T	Chief Executive Officer	S Sale	2026-06-22	2026-06-23	42,305	$17.99	$761.1K	281,212	SEC↗
McNeill Jonathan	President and COO	S Sale	2026-06-22	2026-06-23	20,549	$17.99	$369.7K	139,158	SEC↗
Im Ellie Eunkyung	Chief Medical Officer	S Sale	2026-06-22	2026-06-23	1,219	$17.99	$21.9K	22,069	SEC↗
Bispham Barbara Harlin	See Remarks	S Sale	2026-06-22	2026-06-23	1,218	$17.99	$21.9K	19,330	SEC↗
Scalzo Richard William	Chief Financial Officer	S Sale	2026-06-22	2026-06-23	1,112	$17.99	$20.0K	20,298	SEC↗
Pinkas Jan	Chief Scientific Officer	S Sale	2026-06-22	2026-06-23	1,288	$17.99	$23.2K	22,239	SEC↗
Lynch Ryan	See Remarks	S Sale	2026-06-22	2026-06-23	465	$17.99	$8.4K	13,871	SEC↗
Harwin Peter Evan	Director, 10% Owner	A Award deriv	2026-06-02	2026-06-03	11,050	—	$0	11,050	SEC↗
Moran Susan	Director	A Award deriv	2026-06-02	2026-06-03	11,050	—	$0	11,050	SEC↗
Balcom Alexandra	Director	A Award deriv	2026-06-02	2026-06-03	11,050	—	$0	11,050	SEC↗
Lubner David Charles	Director	A Award deriv	2026-06-02	2026-06-03	11,050	—	$0	11,050	SEC↗
Violin Jonathan	Director	A Award deriv	2026-06-02	2026-06-03	11,050	—	$0	11,050	SEC↗
Bispham Barbara Harlin	See Remarks	A Award deriv	2025-12-15	2025-12-17	72,185	—	$0	72,185	SEC↗
Lynch Ryan	See Remarks	A Award deriv	2025-12-15	2025-12-17	33,512	—	$0	33,512	SEC↗
Im Ellie Eunkyung	Chief Medical Officer	A Award deriv	2025-12-15	2025-12-17	65,190	—	$0	65,190	SEC↗
McNeill Jonathan	President and COO	A Award deriv	2025-12-15	2025-12-17	78,029	—	$0	78,029	SEC↗
Scalzo Richard William	Chief Financial Officer	A Award deriv	2025-12-15	2025-12-17	57,688	—	$0	57,688	SEC↗
Brumm Joshua T	Chief Executive Officer	A Award deriv	2025-12-15	2025-12-17	180,467	—	$0	180,467	SEC↗
Doughty Christopher Grant	Chief Business Officer	A Award deriv	2025-12-15	2025-12-17	58,855	—	$0	58,855	SEC↗
Pinkas Jan	Chief Scientific Officer	A Award deriv	2025-12-15	2025-12-17	70,025	—	$0	70,025	SEC↗
Bispham Barbara Harlin	See Remarks	A Award	2025-12-15	2025-12-17	12,422	—	$0	12,422	SEC↗
Bispham Barbara Harlin	See Remarks	A Award	2025-12-15	2025-12-17	6,000	—	$0	18,422	SEC↗
Lynch Ryan	See Remarks	A Award	2025-12-15	2025-12-17	4,000	—	$0	12,378	SEC↗
Lynch Ryan	See Remarks	A Award	2025-12-15	2025-12-17	8,378	—	$0	8,378	SEC↗
Im Ellie Eunkyung	Chief Medical Officer	A Award	2025-12-15	2025-12-17	16,298	—	$0	16,298	SEC↗
Im Ellie Eunkyung	Chief Medical Officer	A Award	2025-12-15	2025-12-17	5,000	—	$0	21,298	SEC↗
McNeill Jonathan	President and COO	A Award	2025-12-15	2025-12-17	6,000	—	$0	159,707	SEC↗
McNeill Jonathan	President and COO	A Award	2025-12-15	2025-12-17	19,507	—	$0	153,707	SEC↗
Scalzo Richard William	Chief Financial Officer	A Award	2025-12-15	2025-12-17	5,000	—	$0	19,422	SEC↗
Scalzo Richard William	Chief Financial Officer	A Award	2025-12-15	2025-12-17	14,422	—	$0	14,422	SEC↗
Brumm Joshua T	Chief Executive Officer	A Award	2025-12-15	2025-12-17	10,000	—	$0	323,517	SEC↗
Brumm Joshua T	Chief Executive Officer	A Award	2025-12-15	2025-12-17	45,117	—	$0	313,517	SEC↗
Doughty Christopher Grant	Chief Business Officer	A Award	2025-12-15	2025-12-17	8,000	—	$0	62,194	SEC↗
Doughty Christopher Grant	Chief Business Officer	A Award	2025-12-15	2025-12-17	14,714	—	$0	54,194	SEC↗
Pinkas Jan	Chief Scientific Officer	A Award	2025-12-15	2025-12-17	17,507	—	$0	17,507	SEC↗
Pinkas Jan	Chief Scientific Officer	A Award	2025-12-15	2025-12-17	5,000	—	$0	22,507	SEC↗
Brumm Joshua T	Chief Executive Officer	A Award deriv	2025-12-08	2025-12-10	345,672	—	$0	345,672	SEC↗
McNeill Jonathan	President and COO	A Award deriv	2025-12-08	2025-12-10	172,836	—	$0	172,836	SEC↗
Harwin Peter Evan	Director, 10% Owner	P Buy deriv	2025-12-04	2025-12-08	131,434	$13.41	$1.76M	1,768,140	SEC↗
Harwin Peter Evan	Director, 10% Owner	P Buy	2025-12-04	2025-12-08	1,360,000	$13.41	$18.24M	2,747,866	SEC↗
Pinkas Jan	Chief Scientific Officer	A Award deriv	2025-07-16	2025-07-16	142,474	—	$0	142,474	SEC↗
Lubner David Charles	Director	A Award deriv	2025-06-23	2025-06-23	9,023	—	$0	9,023	SEC↗
Balcom Alexandra	Director	A Award deriv	2025-06-23	2025-06-23	9,023	—	$0	9,023	SEC↗
Violin Jonathan	Director	A Award deriv	2025-06-23	2025-06-23	9,023	—	$0	9,023	SEC↗
Harwin Peter Evan	Director, 10% Owner	A Award deriv	2025-06-23	2025-06-23	9,023	—	$0	9,023	SEC↗
Moran Susan	Director	A Award deriv	2025-06-23	2025-06-23	9,023	—	$0	9,023	SEC↗
BVF GP HOLDINGS LLC	10% Owner	J Other deriv	2025-06-13	2025-06-17	304,098	—	$0	304,098	SEC↗
BVF GP HOLDINGS LLC	10% Owner	J Other deriv	2025-06-13	2025-06-17	257,515	—	$0	257,515	SEC↗
BVF GP HOLDINGS LLC	10% Owner	J Other deriv	2025-06-13	2025-06-17	25,944	—	$0	25,944	SEC↗
BVF GP HOLDINGS LLC	10% Owner	J Other	2025-06-13	2025-06-17	657,308	—	$0	707,116	SEC↗
BVF GP HOLDINGS LLC	10% Owner	J Other	2025-06-13	2025-06-17	556,617	—	$0	593,740	SEC↗
BVF GP HOLDINGS LLC	10% Owner	J Other	2025-06-13	2025-06-17	56,079	—	$0	62,383	SEC↗
GNI Hong Kong Ltd	10% Owner	J Other deriv	2023-10-27	2023-10-27	10,577	—	$0	0	SEC↗
GNI Hong Kong Ltd	10% Owner	J Other	2023-10-27	2023-10-27	5,371,304	—	$0	0	SEC↗
LAWLOR AUGUSTINE	Director	D To issuer	2023-08-31	2023-09-01	25	—	$0	0	SEC↗
LAWLOR AUGUSTINE	Director	D To issuer	2023-08-31	2023-09-01	24	—	$0	0	SEC↗
GNI Hong Kong Ltd	10% Owner	D To issuer	2023-08-31	2023-09-01	895	—	$0	0	SEC↗
GNI Hong Kong Ltd	10% Owner	D To issuer	2023-08-31	2023-09-01	5,371	—	$0	0	SEC↗
USMAN NASSIM	President & CEO	D To issuer	2023-08-31	2023-09-01	25	—	$0	0	SEC↗
USMAN NASSIM	President & CEO	D To issuer	2023-08-31	2023-09-01	8	—	$0	0	SEC↗
USMAN NASSIM	President & CEO	D To issuer	2023-08-31	2023-09-01	1	—	$0	0	SEC↗
Hunt Andrea	Director	D To issuer	2023-08-31	2023-09-01	28	—	$0	0	SEC↗
Miller Seline E.	SVP Finance; Interim CFO & P	D To issuer	2023-08-31	2023-09-01	7	—	$0	0	SEC↗
Blouse Grant E.	Chief Scientific Officer	P Buy	2022-08-09	2022-08-10	3,250	$0.47	$1.5K	9,417	SEC↗
Miller Seline E.	SVP Finance; Interim CFO & P	P Buy	2022-08-09	2022-08-10	3,250	$0.47	$1.5K	6,500	SEC↗
USMAN NASSIM	President & CEO	P Buy	2022-08-09	2022-08-10	3,250	$0.47	$1.5K	24,541	SEC↗
Blouse Grant E.	Chief Scientific Officer	A Award deriv	2022-02-11	2022-02-23	200,000	—	$0	200,000	SEC↗
Miller Seline E.	SVP Finance; Interim CFO & P	A Award deriv	2022-02-11	2022-02-23	107,500	—	$0	107,500	SEC↗
Blouse Grant E.	Chief Scientific Officer	P Buy	2022-02-09	2022-02-16	3,250	$0.46	$1.5K	6,167	SEC↗
Miller Seline E.	SVP Finance; Interim CFO & P	P Buy	2022-02-09	2022-02-16	3,250	$0.46	$1.5K	3,250	SEC↗
USMAN NASSIM	President & CEO	P Buy	2022-02-09	2022-02-16	3,250	$0.46	$1.5K	21,291	SEC↗
Hunt Andrea	Director	A Award	2022-01-07	2022-01-07	7,521	—	$0	28,228	SEC↗
Ling Geoffrey M.D.	Director	A Award	2022-01-07	2022-01-07	12,855	—	$0	31,790	SEC↗
Williams Eddie	Director	A Award	2022-01-07	2022-01-07	12,308	—	$0	34,804	SEC↗
DESOUZA ERROL B	Director	A Award	2021-10-01	2021-10-05	3,588	—	$0	29,801	SEC↗
Hunt Andrea	Director	A Award	2021-10-01	2021-10-05	1,824	—	$0	20,707	SEC↗
LAWLOR AUGUSTINE	Director	A Award	2021-10-01	2021-10-05	5,839	—	$0	24,573	SEC↗
Ling Geoffrey M.D.	Director	A Award	2021-10-01	2021-10-05	2,858	—	$0	18,935	SEC↗
Williams Eddie	Director	A Award	2021-10-01	2021-10-05	2,980	—	$0	22,496	SEC↗
JEW JEANNE Y	Director	A Award deriv	2021-09-09	2021-09-13	28,000	—	$0	28,000	SEC↗
Blouse Grant E.	Chief Scientific Officer	P Buy	2021-08-09	2021-08-11	1,163	$3.62	$4.2K	2,917	SEC↗
Levy Howard	Chief Medical Officer	P Buy	2021-08-09	2021-08-11	639	$3.62	$2.3K	639	SEC↗
USMAN NASSIM	President & CEO	P Buy	2021-08-09	2021-08-11	867	$3.62	$3.1K	18,041	SEC↗
DESOUZA ERROL B	Director	A Award	2021-07-01	2021-07-02	3,406	—	$0	26,213	SEC↗
Hunt Andrea	Director	A Award	2021-07-01	2021-07-02	2,886	—	$0	18,883	SEC↗
LAWLOR AUGUSTINE	Director	A Award	2021-07-01	2021-07-02	5,542	—	$0	18,734	SEC↗
Ling Geoffrey M.D.	Director	A Award	2021-07-01	2021-07-02	2,713	—	$0	16,077	SEC↗
Williams Eddie	Director	A Award	2021-07-01	2021-07-02	1,414	—	$0	19,516	SEC↗
DESOUZA ERROL B	Director	A Award deriv	2021-06-09	2021-07-02	14,000	—	$0	14,000	SEC↗
Hunt Andrea	Director	A Award deriv	2021-06-09	2021-07-02	14,000	—	$0	14,000	SEC↗
LAWLOR AUGUSTINE	Director	A Award deriv	2021-06-09	2021-07-02	14,000	—	$0	14,000	SEC↗
Ling Geoffrey M.D.	Director	A Award deriv	2021-06-09	2021-07-02	14,000	—	$0	14,000	SEC↗
TETLOW SHARON	Director	A Award deriv	2021-06-09	2021-07-02	14,000	—	$0	14,000	SEC↗
Williams Eddie	Director	A Award deriv	2021-06-09	2021-07-02	14,000	—	$0	14,000	SEC↗
USMAN NASSIM	President & CEO	M Exercise deriv	2021-04-05	2021-04-07	5,000	—	$0	259,783	SEC↗
USMAN NASSIM	President & CEO	M Exercise	2021-04-05	2021-04-07	5,000	$4.63	$23.1K	17,174	SEC↗
DESOUZA ERROL B	Director	A Award	2021-04-01	2021-04-05	2,926	—	$0	22,807	SEC↗
Hunt Andrea	Director	A Award	2021-04-01	2021-04-05	2,480	—	$0	15,997	SEC↗
LAWLOR AUGUSTINE	Director	A Award	2021-04-01	2021-04-05	4,761	—	$0	13,192	SEC↗
Ling Geoffrey M.D.	Director	A Award	2021-04-01	2021-04-05	2,331	—	$0	13,364	SEC↗
Williams Eddie	Director	A Award	2021-04-01	2021-04-05	1,215	—	$0	18,102	SEC↗
Levy Howard	Chief Medical Officer	P Buy	2021-02-09	2021-02-22	1,670	$4.81	$8.0K	23,390	SEC↗
USMAN NASSIM	President & CEO	P Buy	2021-02-09	2021-02-22	582	$4.81	$2.8K	12,174	SEC↗
Levy Howard	Chief Medical Officer	A Award deriv	2021-02-08	2021-04-26	25,000	—	$0	25,000	SEC↗
Musil Clinton	Chief Financial Officer	A Award deriv	2021-02-08	2021-04-26	54,000	—	$0	54,000	SEC↗
USMAN NASSIM	President & CEO	A Award deriv	2021-02-08	2021-04-26	140,000	—	$0	140,000	SEC↗
Levy Howard	Chief Medical Officer	A Award deriv	2021-02-08	2021-02-10	25,000	—	$0	25,000	SEC↗
Musil Clinton	Chief Financial Officer	A Award deriv	2021-02-08	2021-02-10	54,000	—	$0	54,000	SEC↗
USMAN NASSIM	President & CEO	A Award deriv	2021-02-08	2021-02-10	140,000	—	$0	140,000	SEC↗
DESOUZA ERROL B	Director	A Award	2021-01-05	2021-01-06	2,129	—	$0	19,881	SEC↗
Hunt Andrea	Director	A Award	2021-01-05	2021-01-06	1,881	—	$0	13,517	SEC↗
LAWLOR AUGUSTINE	Director	A Award	2021-01-05	2021-01-06	3,417	—	$0	8,431	SEC↗
Ling Geoffrey M.D.	Director	A Award	2021-01-05	2021-01-06	1,782	—	$0	11,033	SEC↗
Williams Eddie	Director	A Award	2021-01-05	2021-01-06	940	—	$0	16,887	SEC↗
DESOUZA ERROL B	Director	A Award	2020-10-01	2020-10-02	3,125	—	$0	17,752	SEC↗
Hunt Andrea	Director	A Award	2020-10-01	2020-10-02	2,761	—	$0	11,636	SEC↗
LAWLOR AUGUSTINE	Director	A Award	2020-10-01	2020-10-02	5,014	—	$0	5,014	SEC↗
Ling Geoffrey M.D.	Director	A Award	2020-10-01	2020-10-02	2,616	—	$0	9,251	SEC↗
Williams Eddie	Director	A Award	2020-10-01	2020-10-02	1,380	—	$0	15,947	SEC↗
Levy Howard	Chief Medical Officer	P Buy	2020-08-10	2020-08-12	1,768	$4.81	$8.5K	4,268	SEC↗
USMAN NASSIM	President & CEO	P Buy	2020-08-10	2020-08-12	582	$4.81	$2.8K	11,592	SEC↗
Musil Clinton	Chief Financial Officer	A Award deriv	2020-07-01	2020-07-02	140,000	—	$0	140,000	SEC↗
DESOUZA ERROL B	Director	A Award	2020-07-01	2020-07-02	2,129	—	$0	14,627	SEC↗
Hunt Andrea	Director	A Award	2020-07-01	2020-07-02	2,076	—	$0	8,875	SEC↗
LAWLOR AUGUSTINE	Director	A Award	2020-07-01	2020-07-02	3,673	—	$0	24,215	SEC↗
Ling Geoffrey M.D.	Director	A Award	2020-07-01	2020-07-02	1,703	—	$0	6,635	SEC↗
TETLOW SHARON	Director	A Award	2020-07-01	2020-07-02	1,703	—	$0	3,635	SEC↗
Williams Eddie	Director	A Award	2020-07-01	2020-07-02	1,011	—	$0	14,567	SEC↗
DESOUZA ERROL B	Director	A Award deriv	2020-06-11	2020-06-12	5,000	—	$0	5,000	SEC↗
Hunt Andrea	Director	A Award deriv	2020-06-11	2020-06-12	5,000	—	$0	5,000	SEC↗
LAWLOR AUGUSTINE	Director	A Award deriv	2020-06-11	2020-06-12	5,000	—	$0	5,000	SEC↗
Ling Geoffrey M.D.	Director	A Award deriv	2020-06-11	2020-06-12	5,000	—	$0	5,000	SEC↗
TETLOW SHARON	Director	A Award deriv	2020-06-11	2020-06-12	5,000	—	$0	5,000	SEC↗
Williams Eddie	Director	A Award deriv	2020-06-11	2020-06-12	5,000	—	$0	5,000	SEC↗
DESOUZA ERROL B	Director	A Award	2020-04-01	2020-04-03	2,860	—	$0	12,498	SEC↗
Hunt Andrea	Director	A Award	2020-04-01	2020-04-03	1,673	—	$0	6,799	SEC↗
LAWLOR AUGUSTINE	Director	A Award	2020-04-01	2020-04-03	4,934	—	$0	20,542	SEC↗
Ling Geoffrey M.D.	Director	A Award	2020-04-01	2020-04-03	1,932	—	$0	4,932	SEC↗
TETLOW SHARON	Director	A Award	2020-04-01	2020-04-03	1,932	—	$0	1,932	SEC↗
Williams Eddie	Director	A Award	2020-04-01	2020-04-03	2,717	—	$0	13,556	SEC↗
Levy Howard	Chief Medical Officer	P Buy	2020-03-16	2020-03-17	2,500	$4.05	$10.1K	2,500	SEC↗
Cai Veronica	Controller	P Buy	2020-03-13	2020-03-13	2,000	$4.11	$8.2K	7,353	SEC↗
Richard John P	Director	P Buy	2020-03-13	2020-03-13	2,500	$3.98	$9.9K	3,716	SEC↗
USMAN NASSIM	President & CEO	P Buy	2020-03-13	2020-03-13	4,000	$3.91	$15.6K	11,010	SEC↗
Williams Eddie	Director	P Buy	2020-03-04	2020-03-04	2,000	$5.78	$11.6K	10,839	SEC↗
LAWLOR AUGUSTINE	Director	S Sale	2020-02-25	2020-02-25	69,401	$6.10	$423.3K	0	SEC↗
Ling Geoffrey M.D.	Director	P Buy	2020-02-25	2020-02-27	3,000	$6.23	$18.7K	3,000	SEC↗
Cai Veronica	Controller	A Award	2020-02-10	2020-02-12	1,678	$6.23	$10.5K	5,353	SEC↗
Levy Howard	Chief Medical Officer	A Award	2020-02-10	2020-02-12	1,358	$6.23	$8.5K	1,358	SEC↗
USMAN NASSIM	President & CEO	A Award	2020-02-10	2020-02-12	430	$6.23	$2.7K	7,010	SEC↗
Levy Howard	Chief Medical Officer	A Award deriv	2020-01-23	2020-01-27	45,000	—	$0	45,000	SEC↗
USMAN NASSIM	President & CEO	A Award deriv	2020-01-23	2020-01-27	115,000	—	$0	115,000	SEC↗
Cai Veronica	Controller	A Award deriv	2020-01-23	2020-01-27	12,000	—	$0	12,000	SEC↗
Ling Geoffrey M.D.	Director	A Award deriv	2020-01-15	2020-01-17	10,000	—	$0	10,000	SEC↗
TETLOW SHARON	Director	A Award deriv	2020-01-15	2020-01-17	10,000	—	$0	10,000	SEC↗
DESOUZA ERROL B	Director	A Award	2020-01-02	2020-01-02	1,835	—	$0	9,638	SEC↗
Hunt Andrea	Director	A Award	2020-01-02	2020-01-02	1,073	—	$0	5,126	SEC↗
LAWLOR AUGUSTINE	Director	A Award	2020-01-02	2020-01-02	3,166	—	$0	15,608	SEC↗
Williams Eddie	Director	A Award	2020-01-02	2020-01-02	1,743	—	$0	8,839	SEC↗
DESOUZA ERROL B	Director	A Award	2019-10-01	2019-10-02	2,545	—	$0	7,803	SEC↗
Hunt Andrea	Director	A Award	2019-10-01	2019-10-02	1,489	—	$0	4,053	SEC↗
LAWLOR AUGUSTINE	Director	A Award	2019-10-01	2019-10-02	4,391	—	$0	12,442	SEC↗
Williams Eddie	Director	A Award	2019-10-01	2019-10-02	2,418	—	$0	7,096	SEC↗
Cai Veronica	Controller	A Award deriv	2019-09-16	2020-01-27	3,000	—	$0	3,000	SEC↗
USMAN NASSIM	President & CEO	A Award	2019-08-12	2019-08-12	413	$6.51	$2.7K	6,580	SEC↗
Payne Fletcher	Chief Financial Officer	A Award	2019-08-12	2019-08-12	1,180	$6.51	$7.7K	3,744	SEC↗
DESOUZA ERROL B	Director	A Award	2019-07-01	2019-07-02	1,810	—	$0	5,258	SEC↗
Hunt Andrea	Director	A Award	2019-07-01	2019-07-02	1,036	—	$0	2,564	SEC↗
LAWLOR AUGUSTINE	Director	A Award	2019-07-01	2019-07-02	2,905	—	$0	8,051	SEC↗
Williams Eddie	Director	A Award	2019-07-01	2019-07-02	1,642	—	$0	4,678	SEC↗
DESOUZA ERROL B	Director	A Award deriv	2019-06-13	2019-06-17	5,000	—	$0	5,000	SEC↗
Hunt Andrea	Director	A Award deriv	2019-06-13	2019-06-17	5,000	—	$0	5,000	SEC↗
Richard John P	Director	A Award deriv	2019-06-13	2019-06-17	5,000	—	$0	5,000	SEC↗
Williams Eddie	Director	A Award deriv	2019-06-13	2019-06-17	5,000	—	$0	5,000	SEC↗
LAWLOR AUGUSTINE	Director	A Award deriv	2019-06-13	2019-06-17	5,000	—	$0	5,000	SEC↗
Richard John P	Director	P Buy	2019-05-24	2019-05-28	1,000	$8.03	$8.0K	1,216	SEC↗
Levy Howard	Chief Medical Officer	M Exercise	2019-05-21	2019-05-22	4,400	$4.63	$20.4K	16,094	SEC↗
Levy Howard	Chief Medical Officer	G Gift	2019-05-21	2019-05-22	16,094	—	$0	16,094	SEC↗
USMAN NASSIM	President & CEO	G Gift	2019-05-21	2019-05-22	4,400	—	$0	8,456	SEC↗
USMAN NASSIM	President & CEO	G Gift	2019-05-21	2019-05-22	4,400	—	$0	6,167	SEC↗
USMAN NASSIM	President & CEO	M Exercise	2019-05-21	2019-05-22	4,400	$4.63	$20.4K	10,567	SEC↗
Levy Howard	Chief Medical Officer	M Exercise deriv	2019-05-20	2019-05-22	4,400	—	$0	81,218	SEC↗
USMAN NASSIM	President & CEO	M Exercise deriv	2019-05-20	2019-05-22	4,400	—	$0	264,783	SEC↗
DESOUZA ERROL B	Director	A Award	2019-04-01	2019-04-02	1,504	—	$0	3,448	SEC↗
Hunt Andrea	Director	A Award	2019-04-01	2019-04-02	717	—	$0	1,528	SEC↗
LAWLOR AUGUSTINE	Director	A Award	2019-04-01	2019-04-02	2,414	—	$0	5,146	SEC↗
Williams Eddie	Director	A Award	2019-04-01	2019-04-02	1,364	—	$0	3,036	SEC↗
Levy Howard	Chief Medical Officer	A Award	2019-02-11	2019-02-13	2,485	$7.04	$17.5K	11,867	SEC↗
USMAN NASSIM	President & CEO	A Award	2019-02-11	2019-02-13	350	$7.04	$2.5K	6,167	SEC↗
Payne Fletcher	Chief Financial Officer	A Award	2019-02-11	2019-02-13	1,002	$7.04	$7.1K	3,731	SEC↗
Payne Fletcher	Chief Financial Officer	M Exercise deriv	2019-02-04	2019-02-04	1,503	—	$0	73,497	SEC↗
Payne Fletcher	Chief Financial Officer	M Exercise	2019-02-04	2019-02-04	1,503	$4.63	$7.0K	3,230	SEC↗
USMAN NASSIM	President & CEO	M Exercise deriv	2019-01-31	2019-02-04	5,729	—	$0	269,271	SEC↗
Levy Howard	Chief Medical Officer	M Exercise deriv	2019-01-31	2019-02-04	1,500	—	$0	93,500	SEC↗
USMAN NASSIM	President & CEO	M Exercise	2019-01-31	2019-02-04	5,729	$4.63	$26.5K	11,041	SEC↗
Levy Howard	Chief Medical Officer	M Exercise	2019-01-31	2019-02-04	1,500	$4.63	$6.9K	9,382	SEC↗
Levy Howard	Chief Medical Officer	A Award deriv	2019-01-24	2019-01-28	35,000	—	$0	35,000	SEC↗
Payne Fletcher	Chief Financial Officer	A Award deriv	2019-01-24	2019-01-28	38,000	—	$0	38,000	SEC↗
USMAN NASSIM	President and CEO	A Award deriv	2019-01-24	2019-01-28	80,000	—	$0	80,000	SEC↗
DESOUZA ERROL B	Director	A Award	2018-12-31	2019-01-03	1,703	—	$0	1,944	SEC↗
Hunt Andrea	Director	A Award	2018-12-31	2019-01-03	811	—	$0	811	SEC↗
LAWLOR AUGUSTINE	Director	A Award	2018-12-31	2019-01-03	2,732	—	$0	2,732	SEC↗
Williams Eddie	Director	A Award	2018-12-31	2019-01-03	1,544	—	$0	1,672	SEC↗
Levy Howard	Chief Medical Officer	M Exercise deriv	2018-11-26	2018-11-27	149	—	$0	87,118	SEC↗
Levy Howard	Chief Medical Officer	M Exercise	2018-11-26	2018-11-27	149	$4.63	$690	7,709	SEC↗
Levy Howard	Chief Medical Officer	M Exercise deriv	2018-11-16	2018-11-16	173	—	$0	87,267	SEC↗
Levy Howard	Chief Medical Officer	S Sale	2018-11-16	2018-11-16	173	$11.00	$1.9K	7,560	SEC↗
Levy Howard	Chief Medical Officer	M Exercise	2018-11-16	2018-11-16	173	$4.63	$801	7,733	SEC↗
HILL STEPHEN A	Director	D To issuer	2018-09-06	2018-09-06	190	$10.07	$1.9K	1,190	SEC↗
Levy Howard	Chief Medical Officer	A Award deriv	2018-07-30	2018-08-01	35,000	—	$0	35,000	SEC↗
Payne Fletcher	Chief Financial Officer	A Award deriv	2018-07-30	2018-08-01	25,000	—	$0	25,000	SEC↗
USMAN NASSIM	President & CEO	A Award deriv	2018-07-30	2018-08-01	75,000	—	$0	75,000	SEC↗
DESOUZA ERROL B	Director	A Award deriv	2018-06-13	2018-06-15	5,000	—	$0	5,000	SEC↗
HILL STEPHEN A	Director	A Award deriv	2018-06-13	2018-06-15	5,000	—	$0	5,000	SEC↗
Hunt Andrea	Director	A Award deriv	2018-06-13	2018-06-15	5,000	—	$0	5,000	SEC↗
LAWLOR AUGUSTINE	Director	A Award deriv	2018-06-13	2018-06-15	5,000	—	$0	5,000	SEC↗
Richard John P	Director	A Award deriv	2018-06-13	2018-06-15	5,000	—	$0	5,000	SEC↗
Williams Eddie	Director	A Award deriv	2018-06-13	2018-06-15	5,000	—	$0	5,000	SEC↗
Levy Howard	Chief Medical Officer	M Exercise deriv	2018-05-03	2018-05-04	7,560	—	$0	87,440	SEC↗
Levy Howard	Chief Medical Officer	M Exercise	2018-05-03	2018-05-04	7,560	$4.63	$35.0K	7,560	SEC↗
USMAN NASSIM	President & CEO	G Gift	2018-04-09	2018-04-11	88	—	$0	0	SEC↗
USMAN NASSIM	President & CEO	G Gift	2018-04-09	2018-04-11	88	—	$0	4,144	SEC↗
USMAN NASSIM	President & CEO	M Exercise deriv	2018-04-04	2018-04-06	88	—	$0	274,912	SEC↗
USMAN NASSIM	President & CEO	M Exercise	2018-04-04	2018-04-06	88	$4.63	$407	88	SEC↗
Payne Fletcher	Chief Financial Officer	M Exercise deriv	2018-03-26	2018-03-28	59	—	$0	74,941	SEC↗
Payne Fletcher	Chief Financial Officer	M Exercise	2018-03-26	2018-03-28	59	$4.63	$273	59	SEC↗
DEERFIELD MANAGEMENT COMPANY,	10% Owner	S Sale	2018-03-08	2018-03-08	8,123	$29.03	$235.8K	1,113,222	SEC↗
DEERFIELD MANAGEMENT COMPANY,	10% Owner	S Sale	2018-03-08	2018-03-08	1,194	$30.00	$35.8K	1,121,345	SEC↗
Deerfield Mgmt L.P.	10% Owner	S Sale	2018-03-08	2018-03-21	5,890	$29.03	$171.0K	807,257	SEC↗
Deerfield Mgmt L.P.	10% Owner	S Sale	2018-03-08	2018-03-21	866	$30.00	$26.0K	813,147	SEC↗
Deerfield Mgmt L.P.	10% Owner	S Sale	2018-03-08	2018-03-21	2,233	$29.03	$64.8K	305,965	SEC↗
Deerfield Mgmt L.P.	10% Owner	S Sale	2018-03-08	2018-03-21	328	$30.00	$9.8K	308,198	SEC↗
DEERFIELD MANAGEMENT COMPANY,	10% Owner	S Sale	2018-03-07	2018-03-08	10,000	$30.00	$300.0K	1,122,539	SEC↗
Deerfield Mgmt L.P.	10% Owner	S Sale	2018-03-07	2018-03-21	2,748	$30.00	$82.4K	308,526	SEC↗
Deerfield Mgmt L.P.	10% Owner	S Sale	2018-03-07	2018-03-21	7,252	$30.00	$217.6K	814,013	SEC↗
DEERFIELD MANAGEMENT COMPANY,	10% Owner	S Sale	2018-03-06	2018-03-08	39,300	$31.18	$1.23M	1,132,539	SEC↗
DEERFIELD MANAGEMENT COMPANY,	10% Owner	S Sale	2018-03-06	2018-03-08	13,161	$29.94	$394.0K	1,171,839	SEC↗
Deerfield Mgmt L.P.	10% Owner	S Sale	2018-03-06	2018-03-21	10,802	$31.18	$336.8K	311,274	SEC↗
Deerfield Mgmt L.P.	10% Owner	S Sale	2018-03-06	2018-03-21	28,498	$31.18	$888.6K	821,265	SEC↗
Deerfield Mgmt L.P.	10% Owner	S Sale	2018-03-06	2018-03-21	3,617	$29.94	$108.3K	322,076	SEC↗
Deerfield Mgmt L.P.	10% Owner	S Sale	2018-03-06	2018-03-21	9,544	$29.94	$285.7K	849,763	SEC↗
DESOUZA ERROL B	Director	J Other deriv	2018-02-20	2018-02-22	4,679	—	$0	0	SEC↗
DESOUZA ERROL B	Director	J Other deriv	2018-02-20	2018-02-22	0	—	$0	0	SEC↗
HILL STEPHEN A	Director	J Other deriv	2018-02-20	2018-02-22	21,600	—	$0	0	SEC↗
HILL STEPHEN A	Director	J Other deriv	2018-02-20	2018-02-22	0	—	$0	0	SEC↗
Richard John P	Director	J Other deriv	2018-02-20	2018-02-22	0	—	$0	0	SEC↗
SELICK HAROLD E	Director	A Award deriv	2018-01-16	2018-01-18	197	—	$0	197	SEC↗
SELICK HAROLD E	Director	D To issuer deriv	2018-01-16	2018-01-18	197	—	$0	0	SEC↗
SELICK HAROLD E	Director	D To issuer deriv	2018-01-16	2018-01-18	550	—	$0	0	SEC↗
SELICK HAROLD E	Director	A Award deriv	2018-01-16	2018-01-18	550	—	$0	550	SEC↗
SELICK HAROLD E	Director	D To issuer deriv	2018-01-16	2018-01-18	450	—	$0	0	SEC↗
SELICK HAROLD E	Director	A Award deriv	2018-01-16	2018-01-18	450	—	$0	450	SEC↗
SELICK HAROLD E	Director	D To issuer deriv	2018-01-16	2018-01-18	500	—	$0	0	SEC↗
SELICK HAROLD E	Director	A Award deriv	2018-01-16	2018-01-18	500	—	$0	500	SEC↗
SELICK HAROLD E	Director	D To issuer deriv	2018-01-16	2018-01-18	10,000	—	$0	0	SEC↗
SELICK HAROLD E	Director	A Award deriv	2018-01-16	2018-01-18	10,000	—	$0	10,000	SEC↗
Levy Howard	Chief Medical Officer	A Award deriv	2018-01-12	2018-01-16	33,000	—	$0	33,000	SEC↗
Payne Fletcher	Chief Financial Officer	A Award deriv	2018-01-12	2018-01-16	26,000	—	$0	26,000	SEC↗
USMAN NASSIM	President and CEO	A Award deriv	2018-01-12	2018-01-16	95,000	—	$0	95,000	SEC↗
Williams Eddie	Director	A Award deriv	2018-01-02	2018-01-02	10,000	—	$0	10,000	SEC↗
Richard John P	Director	J Other deriv	2017-12-20	2017-12-22	0	—	$0	0	SEC↗
Hunt Andrea	Director	A Award deriv	2017-10-25	2017-10-26	10,000	—	$0	10,000	SEC↗
DESOUZA ERROL B	Director	A Award deriv	2017-07-13	2017-07-14	10,000	—	$0	10,000	SEC↗
HILL STEPHEN A	Director	A Award deriv	2017-07-13	2017-07-14	10,000	—	$0	10,000	SEC↗
LAWLOR AUGUSTINE	Director	A Award deriv	2017-07-13	2017-07-14	10,000	—	$0	10,000	SEC↗
SELICK HAROLD E	Director	A Award deriv	2017-07-13	2017-07-14	10,000	—	$0	10,000	SEC↗
Richard John P	Director	A Award deriv	2017-07-13	2017-07-17	10,000	—	$0	10,000	SEC↗
USMAN NASSIM	President & CEO	A Award deriv	2017-07-11	2017-07-12	275,000	—	$0	275,000	SEC↗
Payne Fletcher	Chief Financial Officer	A Award deriv	2017-07-11	2017-07-12	75,000	—	$0	75,000	SEC↗
Levy Howard	Chief Medical Officer	A Award deriv	2017-07-11	2017-07-12	95,000	—	$0	95,000	SEC↗
DESOUZA ERROL B	Director	A Award deriv	2016-06-09	2016-06-13	7,500	—	$0	7,500	SEC↗
HILL STEPHEN A	Director	A Award deriv	2016-06-09	2016-06-13	7,500	—	$0	7,500	SEC↗
LAWLOR AUGUSTINE	Director	A Award deriv	2016-06-09	2016-06-13	7,500	—	$0	7,500	SEC↗
Richard John P	Director	A Award deriv	2016-06-09	2016-06-13	7,500	—	$0	7,500	SEC↗
SELICK HAROLD E	Director	A Award deriv	2016-06-09	2016-06-13	7,500	—	$0	7,500	SEC↗
USMAN NASSIM	President and CEO	A Award deriv	2016-06-09	2016-06-13	7,500	—	$0	7,500	SEC↗
USMAN NASSIM	President and CEO	J Other deriv	2016-06-09	2016-06-13	0	—	$0	0	SEC↗
Levy Howard	Chief Medical Officer	A Award deriv	2016-04-18	2016-04-19	100,000	—	$0	100,000	SEC↗
HILL STEPHEN A	Director	P Buy	2015-12-17	2015-12-18	5,000	$2.03	$10.1K	20,711	SEC↗
Payne Fletcher	Chief Financial Officer	P Buy	2015-12-17	2015-12-18	10,000	$2.00	$20.0K	25,032	SEC↗