Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
$17.2K
2 trades · 2 insiders
Net · 90d
$-17.2K
Insiders on file
41
Daily buy vs sell · 90 days
■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| MOORE ALISON | President and CEO, Director | 15 | $0 | $29.3K | 2026-10-12 |
| Erbez Georgia | See Remarks | 8 | $0 | $29.3K | 2026-10-12 |
| De Vre Raymond | Director | 5 | $0 | $8.6K | 2026-06-17 |
| Martinborough Esther | Director | 7 | $0 | $0 | 2026-06-17 |
| Richards Christos | Director | 3 | $0 | $0 | 2026-06-17 |
| Collins Cynthia | Director | 3 | $0 | $0 | 2026-06-17 |
| DILLY STEPHEN GEORGE | See Remarks | 16 | $101.2K | $252.3K | 2026-06-17 |
| Singhvi Rahul | Director | 6 | $0 | $0 | 2026-06-17 |
| Smith David V | Director | 17 | $0 | $62.2K | 2026-06-17 |
| PARKER H STEWART | Director | 5 | $0 | $0 | 2026-06-17 |
| Lutz Stefan | Chief Scientific Officer | 4 | $0 | $17.9K | 2026-02-24 |
| Opaleye Management Inc. | 10% Owner | 71 | $13.73M | $7.60M | 2025-12-01 |
| WOLF DENNIS P | Director | 52 | $0 | $3.48M | 2025-11-21 |
| Norrett Kevin | Chief Operating Officer | 11 | $15.5K | $77.2K | 2025-02-05 |
| Dorgan Byron L | Director | 34 | $0 | $3.35M | 2024-06-11 |
| Fitzgerald Margaret Nell | See remarks | 9 | $20.1K | $71.8K | 2024-01-01 |
| Ryali Sriram | Chief Financial Officer | 5 | $19.8K | $0 | 2024-01-01 |
| Aaker Jennifer | Director | 4 | $0 | $0 | 2023-06-13 |
| NICOLS JOHN J | President and CEO | 155 | $450.9K | $16.21M | 2023-04-18 |
| TAYLOR DEAN ROSS JR | SVP, Chief Scientific Officer | 16 | $0 | $0 | 2023-02-07 |
| Yang Patrick Y | Director | 36 | $816.3K | $6.07M | 2022-06-14 |
| KELLEY BERNARD J | Director | 40 | $0 | $2.36M | 2021-08-10 |
| BARUCH THOMAS R | Director | 27 | $0 | $2.65M | 2020-06-12 |
| Cheng Pam P. | Director | 9 | $0 | $549.8K | 2019-06-11 |
| Glaub Kathleen Sereda | Director | 9 | $0 | $786.8K | 2019-06-11 |
| Lalonde James | SVP, R&D | 50 | $0 | $2.01M | 2019-05-14 |
| SANGSTER GORDON | SVP & Chief Financial Officer | 41 | $0 | $4.85M | 2019-03-21 |
| Aldridge Michael D. | See Remarks | 11 | $0 | $581.9K | 2018-05-17 |
| Vivo Ventures VII Affiliates Fund, L.P. | 10% Owner | 2 | $0 | $6.13M | 2017-09-14 |
| Vivo Ventures Fund VII, L.P. | 10% Owner | 2 | $0 | $474.3K | 2016-09-08 |
| VIVO VENTURES VII, LLC | 10% Owner | 8 | $0 | $706.3K | 2016-08-16 |
| Sheehy Douglas T. | See Remarks | 19 | $0 | $10.5K | 2016-03-05 |
| CMEA Ventures LS Management 2000, L.P. | 10% Owner | 2 | $0 | $6.92M | 2014-11-10 |
| Karsner Alexander | Director | 3 | $0 | $0 | 2014-01-02 |
| O'Toole David D | SVP & Chief Financial Officer | 9 | $45.1K | $0 | 2013-09-04 |
| Tobin Matthew | SVP, Research & Development | 5 | $0 | $0 | 2013-05-16 |
| Anton David L. | SVP, BioIndustrials | 6 | $0 | $10.5K | 2013-02-10 |
| Seufer-Wasserthal Peter | SVP, Pharmaceuticals | 2 | $0 | $0 | 2013-01-24 |
| Dowd Brian Paul | Interim CFO | 3 | $0 | $0 | 2012-06-01 |
| Strumph Peter M | Interim President and CEO | 5 | $0 | $0 | 2012-06-01 |
| Sarret Joseph J. | SVP and CBO | 2 | $0 | $0 | 2012-03-07 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Erbez Georgia | See Remarks | S Sale | 2026-10-12 | 2026-10-14 | 6,335 | $1.36 | $8.6K | 60,475 | SEC↗ |
| MOORE ALISON | President and CEO, Director | S Sale | 2026-10-12 | 2026-10-14 | 6,335 | $1.36 | $8.6K | 244,171 | SEC↗ |
| De Vre Raymond | Director | A Award deriv | 2026-06-17 | 2026-06-18 | 66,350 | — | $0 | 66,350 | SEC↗ |
| DILLY STEPHEN GEORGE | Director | A Award deriv | 2026-06-17 | 2026-06-18 | 66,350 | — | $0 | 66,350 | SEC↗ |
| Martinborough Esther | Director | A Award deriv | 2026-06-17 | 2026-06-18 | 66,350 | — | $0 | 66,350 | SEC↗ |
| Singhvi Rahul | Director | A Award deriv | 2026-06-17 | 2026-06-18 | 66,350 | — | $0 | 66,350 | SEC↗ |
| Smith David V | Director | A Award deriv | 2026-06-17 | 2026-06-18 | 66,350 | — | $0 | 66,350 | SEC↗ |
| Richards Christos | Director | A Award deriv | 2026-06-17 | 2026-06-18 | 66,350 | — | $0 | 66,350 | SEC↗ |
| Collins Cynthia | Director | A Award deriv | 2026-06-17 | 2026-06-18 | 66,350 | — | $0 | 66,350 | SEC↗ |
| PARKER H STEWART | Director | A Award deriv | 2026-06-17 | 2026-06-18 | 66,350 | — | $0 | 66,350 | SEC↗ |
| De Vre Raymond | Director | S Sale | 2026-06-11 | 2026-06-11 | 2,605 | $2.37 | $6.2K | 84,811 | SEC↗ |
| Lutz Stefan | Chief Scientific Officer | S Sale | 2026-02-24 | 2026-02-25 | 5,862 | $1.13 | $6.6K | 130,421 | SEC↗ |
| Erbez Georgia | See Remarks | A Award deriv | 2026-02-23 | 2026-02-25 | 316,100 | — | $0 | 316,100 | SEC↗ |
| MOORE ALISON | President and CEO | A Award deriv | 2026-02-23 | 2026-02-25 | 993,000 | — | $0 | 993,000 | SEC↗ |
| Lutz Stefan | Chief Scientific Officer | A Award deriv | 2026-02-23 | 2026-02-25 | 316,100 | — | $0 | 316,100 | SEC↗ |
| MOORE ALISON | President and CEO | S Sale | 2026-02-06 | 2026-02-09 | 3,826 | $1.31 | $5.0K | 250,506 | SEC↗ |
| Erbez Georgia | See Remarks | S Sale | 2026-02-06 | 2026-02-09 | 3,826 | $1.31 | $5.0K | 66,810 | SEC↗ |
| Lutz Stefan | Chief Scientific Officer | S Sale | 2026-02-06 | 2026-02-09 | 2,492 | $1.31 | $3.3K | 136,283 | SEC↗ |
| Lutz Stefan | CSO | S Sale | 2026-01-07 | 2026-01-08 | 4,685 | $1.70 | $8.0K | 138,775 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-12-01 | 2025-12-01 | 245,000 | $1.67 | $409.1K | 9,955,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-12-01 | 2025-12-01 | 8,533 | $1.67 | $14.3K | 179,989 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-12-01 | 2025-12-15 | 8,533 | $1.67 | $14.3K | 179,989 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-12-01 | 2025-12-15 | 245,000 | $1.67 | $409.1K | 9,955,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-28 | 2025-12-01 | 105,000 | $1.75 | $183.8K | 10,200,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-28 | 2025-12-01 | 2,490 | $1.75 | $4.4K | 188,522 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-28 | 2025-12-15 | 105,000 | $1.75 | $183.8K | 10,200,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-28 | 2025-12-15 | 2,490 | $1.75 | $4.4K | 188,522 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-26 | 2025-12-01 | 5,000 | $1.74 | $8.7K | 191,012 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-26 | 2025-12-01 | 148,318 | $1.74 | $258.1K | 10,305,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-26 | 2025-12-15 | 148,318 | $1.74 | $258.1K | 10,305,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-26 | 2025-12-15 | 5,000 | $1.74 | $8.7K | 191,012 | SEC↗ |
| WOLF DENNIS P | Director | S Sale | 2025-11-21 | 2025-11-25 | 8,952 | $1.56 | $14.0K | 138,951 | SEC↗ |
| MOORE ALISON | President and CEO | A Award deriv | 2025-11-13 | 2025-11-17 | 500,000 | — | $0 | 500,000 | SEC↗ |
| MOORE ALISON | President and CEO | A Award | 2025-11-13 | 2025-11-17 | 85,000 | — | $0 | 254,332 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-12 | 2025-11-14 | 165,000 | $1.96 | $323.4K | 10,453,318 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-12 | 2025-11-14 | 27,459 | $1.94 | $53.3K | 196,012 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-12 | 2025-11-14 | 890,000 | $1.94 | $1.73M | 10,618,318 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-11 | 2025-11-12 | 535,000 | $1.80 | $963.0K | 11,508,318 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-11 | 2025-11-12 | 13,211 | $1.80 | $23.8K | 223,461 | SEC↗ |
| DILLY STEPHEN GEORGE | Director | A Award | 2025-11-11 | 2025-11-12 | 50,000 | $1.85 | $92.5K | 727,053 | SEC↗ |
| De Vre Raymond | Director | S Sale | 2025-11-11 | 2025-11-13 | 1,413 | $1.74 | $2.5K | 87,416 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-11 | 2025-12-15 | 13,211 | $1.80 | $23.8K | 223,461 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-11 | 2025-12-15 | 535,000 | $1.80 | $963.0K | 11,508,318 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-10 | 2025-11-12 | 205,000 | $1.73 | $354.6K | 12,043,318 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-10 | 2025-11-12 | 3,318 | $1.73 | $5.7K | 236,682 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-10 | 2025-12-15 | 3,318 | $1.73 | $5.7K | 236,682 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-10 | 2025-12-15 | 205,000 | $1.73 | $354.6K | 12,043,318 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-07 | 2025-11-12 | 296,682 | $1.70 | $504.4K | 12,248,318 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-07 | 2025-11-12 | 10,000 | $1.70 | $17.0K | 240,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-07 | 2025-12-15 | 10,000 | $1.70 | $17.0K | 240,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2025-11-07 | 2025-12-15 | 296,682 | $1.70 | $504.4K | 12,248,318 | SEC↗ |
| Erbez Georgia | Chief Financial Officer | S Sale | 2025-10-13 | 2025-10-15 | 6,239 | $2.51 | $15.7K | 70,636 | SEC↗ |
| MOORE ALISON | Chief Technical Officer | S Sale | 2025-10-13 | 2025-10-15 | 6,239 | $2.51 | $15.7K | 169,332 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-08-04 | 2025-08-04 | 780 | $2.84 | $2.2K | 12,545,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-07-31 | 2025-08-04 | 84,220 | $2.68 | $225.7K | 12,544,220 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-07-30 | 2025-07-31 | 1,578 | $2.80 | $4.4K | 12,460,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-07-29 | 2025-07-31 | 8,422 | $2.82 | $23.8K | 12,458,422 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-07-18 | 2025-07-22 | 100,000 | $2.82 | $282.0K | 12,450,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-06-27 | 2025-07-01 | 100,000 | $2.39 | $239.0K | 12,350,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-06-16 | 2025-06-16 | 50,898 | $2.24 | $114.0K | 12,250,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-06-13 | 2025-06-16 | 99,102 | $2.23 | $221.0K | 12,199,102 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-06-12 | 2025-06-16 | 100,000 | $2.25 | $225.0K | 12,100,000 | SEC↗ |
| Collins Cynthia | Director | A Award | 2025-06-10 | 2025-06-12 | 40,983 | — | $0 | 112,157 | SEC↗ |
| De Vre Raymond | Director | A Award | 2025-06-10 | 2025-06-12 | 40,983 | — | $0 | 88,829 | SEC↗ |
| Martinborough Esther | Director | A Award | 2025-06-10 | 2025-06-12 | 40,983 | — | $0 | 129,036 | SEC↗ |
| PARKER H STEWART | Director | A Award | 2025-06-10 | 2025-06-12 | 40,983 | — | $0 | 143,583 | SEC↗ |
| Richards Christos | Director | A Award | 2025-06-10 | 2025-06-12 | 40,983 | — | $0 | 85,133 | SEC↗ |
| Singhvi Rahul | Director | A Award | 2025-06-10 | 2025-06-12 | 40,983 | — | $0 | 137,052 | SEC↗ |
| Smith David V | Director | A Award | 2025-06-10 | 2025-06-12 | 40,983 | — | $0 | 105,705 | SEC↗ |
| WOLF DENNIS P | Director | A Award | 2025-06-10 | 2025-06-12 | 40,983 | — | $0 | 147,903 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-05-28 | 2025-05-28 | 5,000 | $2.36 | $11.8K | 12,000,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-05-23 | 2025-05-28 | 2,320,000 | $2.36 | $5.48M | 11,995,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-05-01 | 2025-05-02 | 20,000 | $2.32 | $46.4K | 9,675,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-04-30 | 2025-05-02 | 25,000 | $2.31 | $57.8K | 9,655,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-04-25 | 2025-04-29 | 25,000 | $2.24 | $56.0K | 9,630,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-04-17 | 2025-04-17 | 45,000 | $2.09 | $94.0K | 9,605,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-04-16 | 2025-04-17 | 70,000 | $2.13 | $149.1K | 9,560,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-04-15 | 2025-04-17 | 25,000 | $2.23 | $55.8K | 9,490,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-04-08 | 2025-04-09 | 100,000 | $1.98 | $198.0K | 9,465,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-04-03 | 2025-04-03 | 75,000 | $2.30 | $172.5K | 9,365,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-04-02 | 2025-04-03 | 5,000 | $2.46 | $12.3K | 9,290,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-04-01 | 2025-04-03 | 35,000 | $2.48 | $86.8K | 9,285,000 | SEC↗ |
| Collins Cynthia | Director | A Award | 2025-03-28 | 2025-04-01 | 71,174 | — | $0 | 71,174 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-03-21 | 2025-03-24 | 92,923 | $2.54 | $236.0K | 9,250,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-03-20 | 2025-03-24 | 7 | $2.54 | $18 | 9,157,077 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-03-13 | 2025-03-14 | 85,000 | $2.54 | $215.9K | 9,150,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-03-06 | 2025-03-10 | 100,000 | $2.61 | $261.0K | 9,065,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-03-05 | 2025-03-06 | 10,000 | $2.69 | $26.9K | 8,965,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-03-04 | 2025-03-06 | 55,000 | $2.64 | $145.2K | 8,955,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-03-03 | 2025-03-04 | 47,351 | $2.81 | $133.1K | 8,900,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-02-28 | 2025-03-04 | 147,649 | $2.99 | $441.5K | 8,852,649 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-02-12 | 2025-02-12 | 15,000 | $4.00 | $60.0K | 8,705,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-02-11 | 2025-02-12 | 12,500 | $4.11 | $51.4K | 8,690,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-02-10 | 2025-02-12 | 22,500 | $4.18 | $94.0K | 8,677,500 | SEC↗ |
| DILLY STEPHEN GEORGE | See Remarks | A Award deriv | 2025-02-05 | 2025-02-07 | 532,500 | — | $0 | 532,500 | SEC↗ |
| Erbez Georgia | Chief Financial Officer | A Award deriv | 2025-02-05 | 2025-02-07 | 161,250 | — | $0 | 161,250 | SEC↗ |
| MOORE ALISON | Chief Technical Officer | A Award deriv | 2025-02-05 | 2025-02-07 | 161,250 | — | $0 | 161,250 | SEC↗ |
| Norrett Kevin | Chief Operating Officer | A Award deriv | 2025-02-05 | 2025-02-07 | 161,250 | — | $0 | 161,250 | SEC↗ |
| DILLY STEPHEN GEORGE | See Remarks | A Award | 2025-02-05 | 2025-02-07 | 88,750 | — | $0 | 673,053 | SEC↗ |
| Erbez Georgia | Chief Financial Officer | A Award | 2025-02-05 | 2025-02-07 | 26,875 | — | $0 | 76,875 | SEC↗ |
| MOORE ALISON | Chief Technical Officer | A Award | 2025-02-05 | 2025-02-07 | 26,875 | — | $0 | 175,571 | SEC↗ |
| Norrett Kevin | Chief Operating Officer | A Award | 2025-02-05 | 2025-02-07 | 26,875 | — | $0 | 177,327 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-01-31 | 2025-01-31 | 45,000 | $4.29 | $193.1K | 8,655,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2025-01-30 | 2025-01-31 | 20,000 | $4.49 | $89.8K | 8,610,000 | SEC↗ |
| Richards Christos | Director | A Award | 2025-01-14 | 2025-01-16 | 44,150 | — | $0 | 44,150 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2024-12-31 | 2025-01-02 | 10,000 | $4.66 | $46.6K | 8,590,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2024-12-30 | 2025-01-02 | 35,000 | $4.70 | $164.5K | 8,580,000 | SEC↗ |
| De Vre Raymond | Director | A Award | 2024-11-07 | 2024-11-12 | 47,846 | — | $0 | 47,846 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2024-10-25 | 2024-10-28 | 25,000 | $2.91 | $72.8K | 8,545,000 | SEC↗ |
| Erbez Georgia | Chief Financial Officer | A Award deriv | 2024-10-10 | 2024-10-10 | 300,000 | — | $0 | 300,000 | SEC↗ |
| MOORE ALISON | Chief Technical Officer | A Award deriv | 2024-10-10 | 2024-10-10 | 300,000 | — | $0 | 300,000 | SEC↗ |
| Erbez Georgia | Chief Financial Officer | A Award | 2024-10-10 | 2024-10-10 | 50,000 | — | $0 | 50,000 | SEC↗ |
| MOORE ALISON | Chief Technical Officer | A Award | 2024-10-10 | 2024-10-10 | 50,000 | — | $0 | 148,696 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2024-09-25 | 2024-09-26 | 5,000 | $2.86 | $14.3K | 8,520,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2024-09-24 | 2024-09-26 | 80,000 | $2.94 | $235.2K | 8,515,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2024-09-23 | 2024-09-23 | 45,000 | $2.94 | $132.3K | 8,435,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2024-09-20 | 2024-09-23 | 45,000 | $3.01 | $135.4K | 250,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2024-09-20 | 2024-09-23 | 1,010,000 | $3.01 | $3.04M | 8,390,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2024-09-18 | 2024-09-19 | 6,000 | $3.16 | $19.0K | 205,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2024-09-18 | 2024-09-19 | 55,000 | $3.16 | $173.8K | 7,380,000 | SEC↗ |
| Dorgan Byron L | Director | A Award | 2024-06-11 | 2024-06-13 | 30,120 | — | $0 | 223,581 | SEC↗ |
| Martinborough Esther | Director | A Award | 2024-06-11 | 2024-06-13 | 30,120 | — | $0 | 88,053 | SEC↗ |
| MOORE ALISON | Director | A Award | 2024-06-11 | 2024-06-13 | 30,120 | — | $0 | 98,696 | SEC↗ |
| PARKER H STEWART | Director | A Award | 2024-06-11 | 2024-06-13 | 30,120 | — | $0 | 102,600 | SEC↗ |
| Singhvi Rahul | Director | A Award | 2024-06-11 | 2024-06-13 | 30,120 | — | $0 | 96,069 | SEC↗ |
| WOLF DENNIS P | Director | A Award | 2024-06-11 | 2024-06-13 | 30,120 | — | $0 | 106,920 | SEC↗ |
| Smith David V | Director | A Award | 2024-06-11 | 2024-06-13 | 30,120 | — | $0 | 64,722 | SEC↗ |
| DILLY STEPHEN GEORGE | See Remarks | A Award deriv | 2024-01-01 | 2024-01-02 | 860,500 | — | $0 | 860,500 | SEC↗ |
| Fitzgerald Margaret Nell | See Remarks | A Award deriv | 2024-01-01 | 2024-01-02 | 314,125 | — | $0 | 314,125 | SEC↗ |
| Norrett Kevin | Chief Operating Officer | A Award deriv | 2024-01-01 | 2024-01-02 | 314,125 | — | $0 | 314,125 | SEC↗ |
| Ryali Sriram | Chief Financial Officer | A Award deriv | 2024-01-01 | 2024-01-02 | 314,125 | — | $0 | 314,125 | SEC↗ |
| DILLY STEPHEN GEORGE | See Remarks | A Award | 2024-01-01 | 2024-01-02 | 143,425 | — | $0 | 582,303 | SEC↗ |
| Fitzgerald Margaret Nell | See Remarks | A Award | 2024-01-01 | 2024-01-02 | 52,350 | — | $0 | 133,770 | SEC↗ |
| Norrett Kevin | Chief Operating Officer | A Award | 2024-01-01 | 2024-01-02 | 52,350 | — | $0 | 150,452 | SEC↗ |
| Ryali Sriram | Chief Financial Officer | A Award | 2024-01-01 | 2024-01-02 | 52,350 | — | $0 | 175,791 | SEC↗ |
| Dorgan Byron L | Director | S Sale | 2023-11-15 | 2023-11-17 | 20,000 | $2.11 | $42.2K | 193,461 | SEC↗ |
| Singhvi Rahul | Director | A Award deriv | 2023-11-09 | 2023-11-14 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Norrett Kevin | Chief Operating Officer | P Buy | 2023-09-11 | 2023-09-12 | 9,000 | $1.72 | $15.5K | 98,102 | SEC↗ |
| DILLY STEPHEN GEORGE | See Remarks | P Buy | 2023-09-08 | 2023-09-12 | 58,479 | $1.73 | $101.2K | 438,878 | SEC↗ |
| Fitzgerald Margaret Nell | See Remarks | P Buy | 2023-09-08 | 2023-09-12 | 11,834 | $1.70 | $20.1K | 81,420 | SEC↗ |
| Ryali Sriram | Chief Financial Officer | P Buy | 2023-09-08 | 2023-09-12 | 11,650 | $1.70 | $19.8K | 123,441 | SEC↗ |
| Smith David V | Director | A Award | 2023-06-13 | 2023-06-15 | 34,602 | — | $0 | 34,602 | SEC↗ |
| Smith David V | Director | G Gift | 2023-06-13 | 2023-06-15 | 11,273 | — | $0 | 0 | SEC↗ |
| Singhvi Rahul | Director | A Award | 2023-06-13 | 2023-06-15 | 34,602 | — | $0 | 65,949 | SEC↗ |
| PARKER H STEWART | Director | A Award | 2023-06-13 | 2023-06-15 | 34,602 | — | $0 | 72,480 | SEC↗ |
| MOORE ALISON | Director | A Award | 2023-06-13 | 2023-06-15 | 34,602 | — | $0 | 68,576 | SEC↗ |
| Dorgan Byron L | Director | A Award | 2023-06-13 | 2023-06-15 | 34,602 | — | $0 | 213,461 | SEC↗ |
| WOLF DENNIS P | Director | A Award | 2023-06-13 | 2023-06-15 | 34,602 | — | $0 | 76,800 | SEC↗ |
| Martinborough Esther | Director | A Award | 2023-06-13 | 2023-06-15 | 34,602 | — | $0 | 57,933 | SEC↗ |
| Aaker Jennifer | Director | A Award | 2023-06-13 | 2023-06-15 | 34,602 | — | $0 | 66,211 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise deriv | 2023-04-18 | 2023-04-19 | 35,714 | — | $0 | 142,856 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2023-04-18 | 2023-04-19 | 35,714 | $4.14 | $147.9K | 783,965 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise | 2023-04-18 | 2023-04-19 | 35,714 | $1.97 | $70.4K | 819,679 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise deriv | 2023-04-17 | 2023-04-19 | 35,714 | — | $0 | 178,570 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise | 2023-04-17 | 2023-04-19 | 35,714 | $1.97 | $70.4K | 819,679 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2023-04-17 | 2023-04-19 | 35,714 | $4.24 | $151.4K | 783,965 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise deriv | 2023-03-16 | 2023-03-17 | 35,714 | — | $0 | 214,284 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise | 2023-03-16 | 2023-03-17 | 35,714 | $1.97 | $70.4K | 819,679 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2023-03-16 | 2023-03-17 | 35,714 | $4.11 | $146.8K | 783,965 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise deriv | 2023-03-15 | 2023-03-17 | 35,714 | — | $0 | 249,998 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise | 2023-03-15 | 2023-03-17 | 35,714 | $1.97 | $70.4K | 819,679 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2023-03-15 | 2023-03-17 | 35,714 | $4.09 | $146.1K | 783,965 | SEC↗ |
| Fitzgerald Margaret Nell | See remarks | S Sale | 2023-03-08 | 2023-03-09 | 7,686 | $4.56 | $35.0K | 69,586 | SEC↗ |
| DILLY STEPHEN GEORGE | See Remarks | S Sale | 2023-03-08 | 2023-03-09 | 26,987 | $4.56 | $123.1K | 380,399 | SEC↗ |
| Norrett Kevin | Chief Operating Officer | S Sale | 2023-03-08 | 2023-03-09 | 8,258 | $4.56 | $37.7K | 89,102 | SEC↗ |
| Fitzgerald Margaret Nell | See remarks | S Sale | 2023-03-07 | 2023-03-09 | 8,000 | $4.60 | $36.8K | 77,272 | SEC↗ |
| DILLY STEPHEN GEORGE | See Remarks | S Sale | 2023-03-07 | 2023-03-09 | 28,088 | $4.60 | $129.2K | 407,386 | SEC↗ |
| Norrett Kevin | Chief Operating Officer | S Sale | 2023-03-07 | 2023-03-09 | 8,596 | $4.60 | $39.5K | 97,360 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise deriv | 2023-02-24 | 2023-02-27 | 35,714 | — | $0 | 285,712 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2023-02-24 | 2023-02-27 | 35,714 | $4.83 | $172.5K | 783,965 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise | 2023-02-24 | 2023-02-27 | 35,714 | $1.97 | $70.4K | 819,679 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2023-02-23 | 2023-02-27 | 39,785 | $5.36 | $213.2K | 783,965 | SEC↗ |
| DILLY STEPHEN GEORGE | See Remarks | A Award deriv | 2023-02-21 | 2023-02-21 | 337,500 | — | $0 | 337,500 | SEC↗ |
| Fitzgerald Margaret Nell | See remarks | A Award deriv | 2023-02-21 | 2023-02-21 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Norrett Kevin | Chief Operating Officer | A Award deriv | 2023-02-21 | 2023-02-21 | 67,500 | — | $0 | 67,500 | SEC↗ |
| DILLY STEPHEN GEORGE | See Remarks | A Award | 2023-02-21 | 2023-02-21 | 112,500 | — | $0 | 146,474 | SEC↗ |
| Fitzgerald Margaret Nell | See remarks | A Award | 2023-02-21 | 2023-02-21 | 8,000 | — | $0 | 8,000 | SEC↗ |
| Norrett Kevin | Chief Operating Officer | A Award | 2023-02-21 | 2023-02-21 | 22,500 | — | $0 | 22,500 | SEC↗ |
| Ryali Sriram | Chief Financial Officer | A Award deriv | 2023-02-10 | 2023-02-14 | 372,637 | — | $0 | 372,637 | SEC↗ |
| Ryali Sriram | Chief Financial Officer | A Award | 2023-02-10 | 2023-02-14 | 111,791 | — | $0 | 111,791 | SEC↗ |
| Fitzgerald Margaret Nell | See remarks | A Award | 2023-02-08 | 2023-03-09 | 77,272 | — | $0 | 85,272 | SEC↗ |
| DILLY STEPHEN GEORGE | See Remarks | A Award | 2023-02-08 | 2023-03-09 | 289,000 | — | $0 | 435,474 | SEC↗ |
| Norrett Kevin | Chief Operating Officer | A Award | 2023-02-08 | 2023-03-09 | 83,456 | — | $0 | 105,956 | SEC↗ |
| TAYLOR DEAN ROSS JR | Other | F Tax w/h | 2023-02-07 | 2023-02-09 | 1,224 | $6.51 | $8.0K | 38,554 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise deriv | 2023-01-24 | 2023-01-25 | 35,714 | — | $0 | 321,426 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2023-01-24 | 2023-01-25 | 35,714 | $6.42 | $229.3K | 823,750 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise | 2023-01-24 | 2023-01-25 | 35,714 | $1.97 | $70.4K | 859,464 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2023-01-23 | 2023-01-25 | 39,785 | $6.58 | $261.8K | 823,750 | SEC↗ |
| PARKER H STEWART | Director | A Award | 2022-12-16 | 2022-12-20 | 37,878 | — | $0 | 37,878 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise deriv | 2022-12-12 | 2022-12-13 | 35,714 | — | $0 | 357,140 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2022-12-12 | 2022-12-13 | 35,714 | $5.68 | $202.9K | 863,535 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise | 2022-12-12 | 2022-12-13 | 35,714 | $1.97 | $70.4K | 899,249 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2022-12-09 | 2022-12-13 | 39,785 | $5.66 | $225.2K | 863,535 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise deriv | 2022-11-16 | 2022-11-17 | 35,714 | — | $0 | 392,854 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise | 2022-11-16 | 2022-11-17 | 35,714 | $1.97 | $70.4K | 939,034 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2022-11-16 | 2022-11-17 | 35,714 | $6.36 | $227.1K | 903,320 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2022-11-15 | 2022-11-17 | 39,786 | $6.79 | $270.1K | 903,320 | SEC↗ |
| Fitzgerald Margaret Nell | See remarks | A Award deriv | 2022-11-08 | 2022-11-10 | 382,775 | — | $0 | 382,775 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise deriv | 2022-10-28 | 2022-10-31 | 35,716 | — | $0 | 428,568 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise | 2022-10-28 | 2022-10-31 | 35,716 | $1.97 | $70.4K | 978,822 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2022-10-28 | 2022-10-31 | 35,716 | $5.53 | $197.5K | 943,106 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2022-10-27 | 2022-10-31 | 39,786 | $5.68 | $226.0K | 943,106 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise deriv | 2022-10-06 | 2022-10-07 | 35,716 | — | $0 | 464,284 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise | 2022-10-06 | 2022-10-07 | 35,716 | $1.97 | $70.4K | 1,018,608 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2022-10-06 | 2022-10-07 | 35,716 | $5.99 | $213.9K | 982,892 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2022-10-05 | 2022-10-07 | 39,787 | $6.04 | $240.3K | 982,892 | SEC↗ |
| Norrett Kevin | Chief Operating Officer | A Award deriv | 2022-10-03 | 2022-10-05 | 413,405 | — | $0 | 413,405 | SEC↗ |
| Singhvi Rahul | Director | A Award | 2022-09-28 | 2022-09-30 | 31,347 | — | $0 | 31,347 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise deriv | 2022-08-15 | 2022-08-16 | 39,000 | — | $0 | 0 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise | 2022-08-15 | 2022-08-16 | 39,000 | $2.32 | $90.5K | 1,061,679 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2022-08-15 | 2022-08-16 | 39,000 | $8.78 | $342.4K | 1,022,679 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise deriv | 2022-08-12 | 2022-08-16 | 38,500 | — | $0 | 39,000 | SEC↗ |
| NICOLS JOHN J | Director | M Exercise | 2022-08-12 | 2022-08-16 | 38,500 | $2.32 | $89.3K | 1,061,179 | SEC↗ |
| NICOLS JOHN J | Director | S Sale | 2022-08-12 | 2022-08-16 | 38,500 | $8.62 | $331.9K | 1,022,679 | SEC↗ |
| DILLY STEPHEN GEORGE | See Remarks | A Award deriv | 2022-08-01 | 2022-08-03 | 700,000 | — | $0 | 700,000 | SEC↗ |
| MOORE ALISON | Director | A Award | 2022-06-14 | 2022-06-16 | 11,273 | — | $0 | 33,974 | SEC↗ |
| Dorgan Byron L | Director | A Award | 2022-06-14 | 2022-06-16 | 11,273 | — | $0 | 178,859 | SEC↗ |
| Smith David V | Director | A Award | 2022-06-14 | 2022-06-16 | 11,273 | — | $0 | 11,273 | SEC↗ |
| Smith David V | Director | G Gift | 2022-06-14 | 2022-06-16 | 4,796 | — | $0 | 0 | SEC↗ |
| WOLF DENNIS P | Director | A Award | 2022-06-14 | 2022-06-16 | 11,273 | — | $0 | 42,198 | SEC↗ |
| Martinborough Esther | Director | A Award | 2022-06-14 | 2022-06-16 | 11,273 | — | $0 | 23,331 | SEC↗ |
| Aaker Jennifer | Director | A Award | 2022-06-14 | 2022-06-16 | 11,273 | — | $0 | 31,609 | SEC↗ |
| Yang Patrick Y | Director | A Award | 2022-06-14 | 2022-06-16 | 11,273 | — | $0 | 53,785 | SEC↗ |
| DILLY STEPHEN GEORGE | Director | A Award | 2022-06-14 | 2022-06-16 | 11,273 | — | $0 | 33,974 | SEC↗ |
| Dorgan Byron L | Director | M Exercise deriv | 2022-05-26 | 2022-05-27 | 20,000 | — | $0 | 0 | SEC↗ |
| Dorgan Byron L | Director | M Exercise | 2022-05-26 | 2022-05-27 | 20,000 | $3.62 | $72.4K | 167,586 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise deriv | 2022-05-12 | 2022-05-13 | 38,500 | — | $0 | 77,500 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2022-05-12 | 2022-05-13 | 16,409 | $10.61 | $174.1K | 1,022,679 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise | 2022-05-12 | 2022-05-13 | 38,500 | $2.32 | $89.3K | 1,061,179 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2022-05-12 | 2022-05-13 | 22,091 | $10.09 | $222.9K | 1,039,088 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise deriv | 2022-05-11 | 2022-05-13 | 38,500 | — | $0 | 116,000 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2022-05-11 | 2022-05-13 | 38,500 | $10.31 | $396.9K | 1,022,679 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise | 2022-05-11 | 2022-05-13 | 38,500 | $2.32 | $89.3K | 1,061,179 | SEC↗ |
| WOLF DENNIS P | Director | S Sale | 2022-03-23 | 2022-03-25 | 4,000 | $20.49 | $82.0K | 30,925 | SEC↗ |
| Yang Patrick Y | Director | S Sale | 2022-03-15 | 2022-03-16 | 8,000 | $16.79 | $134.3K | 42,512 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise deriv | 2022-03-10 | 2022-03-11 | 38,500 | — | $0 | 154,500 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2022-03-10 | 2022-03-11 | 38,500 | $18.93 | $728.8K | 1,022,679 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise | 2022-03-10 | 2022-03-11 | 38,500 | $2.32 | $89.3K | 1,061,179 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise deriv | 2022-03-09 | 2022-03-11 | 38,500 | — | $0 | 193,000 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise | 2022-03-09 | 2022-03-11 | 38,500 | $2.32 | $89.3K | 1,061,179 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2022-03-09 | 2022-03-11 | 38,500 | $19.30 | $743.0K | 1,022,679 | SEC↗ |
| TAYLOR DEAN ROSS JR | SVP, Chief Financial Officer | F Tax w/h | 2022-03-05 | 2022-03-08 | 2,414 | $19.30 | $46.6K | 39,778 | SEC↗ |
| TAYLOR DEAN ROSS JR | SVP, Chief Financial Officer | F Tax w/h | 2022-03-05 | 2022-03-08 | 2,013 | $19.30 | $38.9K | 42,192 | SEC↗ |
| NICOLS JOHN J | President and CEO | A Award deriv | 2022-02-08 | 2022-02-09 | 200,062 | — | $0 | 200,062 | SEC↗ |
| TAYLOR DEAN ROSS JR | SVP, Chief Financial Officer | A Award deriv | 2022-02-08 | 2022-02-09 | 16,006 | — | $0 | 16,006 | SEC↗ |
| TAYLOR DEAN ROSS JR | SVP, Chief Financial Officer | A Award | 2022-02-08 | 2022-02-09 | 11,640 | — | $0 | 35,205 | SEC↗ |
| NICOLS JOHN J | President and CEO | A Award deriv | 2022-02-07 | 2022-02-09 | 40,000 | — | $0 | 40,000 | SEC↗ |
| TAYLOR DEAN ROSS JR | SVP, Chief Financial Officer | A Award deriv | 2022-02-07 | 2022-02-09 | 13,000 | — | $0 | 13,000 | SEC↗ |
| TAYLOR DEAN ROSS JR | SVP, Chief Financial Officer | A Award | 2022-02-07 | 2022-02-09 | 9,000 | — | $0 | 44,205 | SEC↗ |
| WOLF DENNIS P | Director | S Sale | 2021-12-20 | 2021-12-21 | 2,404 | $29.27 | $70.4K | 34,925 | SEC↗ |
| WOLF DENNIS P | Director | S Sale | 2021-12-20 | 2021-12-21 | 2,596 | $28.43 | $73.8K | 37,329 | SEC↗ |
| Yang Patrick Y | Director | S Sale | 2021-12-13 | 2021-12-14 | 200 | $32.14 | $6.4K | 50,512 | SEC↗ |
| Yang Patrick Y | Director | S Sale | 2021-12-13 | 2021-12-14 | 7,800 | $31.59 | $246.4K | 50,712 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise deriv | 2021-11-11 | 2021-11-12 | 38,500 | — | $0 | 231,500 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2021-11-11 | 2021-11-12 | 11,327 | $39.07 | $442.5K | 1,022,679 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise | 2021-11-11 | 2021-11-12 | 38,500 | $2.32 | $89.3K | 1,061,179 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2021-11-11 | 2021-11-12 | 27,173 | $38.19 | $1.04M | 1,034,006 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise deriv | 2021-11-10 | 2021-11-12 | 35,000 | — | $0 | 0 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2021-11-10 | 2021-11-12 | 14,071 | $39.85 | $560.7K | 1,042,133 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise | 2021-11-10 | 2021-11-12 | 35,000 | $3.46 | $121.1K | 1,057,679 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2021-11-10 | 2021-11-12 | 1,475 | $39.12 | $57.7K | 1,056,204 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2021-11-10 | 2021-11-12 | 19,454 | $40.69 | $791.6K | 1,022,679 | SEC↗ |
| Dorgan Byron L | Director | S Sale | 2021-10-18 | 2021-10-19 | 2,600 | $28.53 | $74.2K | 147,586 | SEC↗ |
| Dorgan Byron L | Director | S Sale | 2021-10-18 | 2021-10-19 | 17,400 | $27.86 | $484.8K | 150,186 | SEC↗ |
| WOLF DENNIS P | Director | S Sale | 2021-10-15 | 2021-10-18 | 5,900 | $28.30 | $167.0K | 40,025 | SEC↗ |
| WOLF DENNIS P | Director | S Sale | 2021-10-15 | 2021-10-18 | 100 | $28.78 | $2.9K | 39,925 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise deriv | 2021-08-13 | 2021-08-16 | 35,000 | — | $0 | 35,000 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise | 2021-08-13 | 2021-08-16 | 35,000 | $3.46 | $121.1K | 1,057,679 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2021-08-13 | 2021-08-16 | 35,000 | $23.77 | $832.0K | 1,022,679 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise deriv | 2021-08-12 | 2021-08-16 | 35,000 | — | $0 | 70,000 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2021-08-12 | 2021-08-16 | 934 | $25.29 | $23.6K | 1,022,679 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise | 2021-08-12 | 2021-08-16 | 35,000 | $3.46 | $121.1K | 1,057,679 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2021-08-12 | 2021-08-16 | 34,066 | $24.51 | $835.0K | 1,023,613 | SEC↗ |
| KELLEY BERNARD J | Director | M Exercise deriv | 2021-08-10 | 2021-08-12 | 20,000 | — | $0 | 0 | SEC↗ |
| KELLEY BERNARD J | Director | M Exercise | 2021-08-10 | 2021-08-12 | 20,000 | $3.62 | $72.4K | 226,136 | SEC↗ |
| KELLEY BERNARD J | Director | S Sale | 2021-08-10 | 2021-08-12 | 20,000 | $25.84 | $516.8K | 206,136 | SEC↗ |
| Yang Patrick Y | Director | S Sale | 2021-06-16 | 2021-06-17 | 20,000 | $20.31 | $406.2K | 58,512 | SEC↗ |
| MOORE ALISON | Director | A Award | 2021-06-15 | 2021-06-17 | 4,796 | — | $0 | 22,701 | SEC↗ |
| Dorgan Byron L | Director | A Award | 2021-06-15 | 2021-06-17 | 4,796 | — | $0 | 167,586 | SEC↗ |
| Smith David V | Director | A Award | 2021-06-15 | 2021-06-17 | 4,796 | — | $0 | 4,796 | SEC↗ |
| Smith David V | Director | G Gift | 2021-06-15 | 2021-06-17 | 8,952 | — | $0 | 0 | SEC↗ |
| WOLF DENNIS P | Director | A Award | 2021-06-15 | 2021-06-17 | 4,796 | — | $0 | 45,925 | SEC↗ |
| Martinborough Esther | Director | A Award | 2021-06-15 | 2021-06-17 | 4,796 | — | $0 | 12,058 | SEC↗ |
| Aaker Jennifer | Director | A Award | 2021-06-15 | 2021-06-17 | 4,796 | — | $0 | 20,336 | SEC↗ |
| Yang Patrick Y | Director | A Award | 2021-06-15 | 2021-06-17 | 4,796 | — | $0 | 78,512 | SEC↗ |
| DILLY STEPHEN GEORGE | Director | A Award | 2021-06-15 | 2021-06-17 | 4,796 | — | $0 | 22,701 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise deriv | 2021-05-18 | 2021-05-19 | 35,000 | — | $0 | 105,000 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise | 2021-05-18 | 2021-05-19 | 35,000 | $3.46 | $121.1K | 1,057,679 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2021-05-18 | 2021-05-19 | 13,877 | $18.56 | $257.6K | 1,043,802 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2021-05-18 | 2021-05-19 | 21,123 | $18.93 | $399.9K | 1,022,679 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise deriv | 2021-05-17 | 2021-05-19 | 35,385 | — | $0 | 140,000 | SEC↗ |
| NICOLS JOHN J | President and CEO | M Exercise | 2021-05-17 | 2021-05-19 | 35,385 | $3.46 | $122.4K | 1,058,064 | SEC↗ |
| NICOLS JOHN J | President and CEO | S Sale | 2021-05-17 | 2021-05-19 | 35,385 | $18.12 | $641.2K | 1,022,679 | SEC↗ |
| KELLEY BERNARD J | Director | S Sale | 2021-04-21 | 2021-04-22 | 2,500 | $22.64 | $56.6K | 206,136 | SEC↗ |
| Yang Patrick Y | Director | S Sale | 2021-04-06 | 2021-04-07 | 10,000 | $25.15 | $251.5K | 73,716 | SEC↗ |
| Yang Patrick Y | Director | S Sale | 2021-04-05 | 2021-04-07 | 10,000 | $24.27 | $242.7K | 83,716 | SEC↗ |
| WOLF DENNIS P | Director | S Sale | 2021-03-25 | 2021-03-29 | 5,142 | $20.07 | $103.2K | 45,987 | SEC↗ |
| WOLF DENNIS P | Director | S Sale | 2021-03-25 | 2021-03-29 | 4,858 | $20.82 | $101.1K | 41,129 | SEC↗ |
| KELLEY BERNARD J | Director | M Exercise deriv | 2021-03-08 | 2021-03-09 | 20,000 | — | $0 | 0 | SEC↗ |
| KELLEY BERNARD J | Director | S Sale | 2021-03-08 | 2021-03-09 | 20,000 | $18.72 | $374.4K | 208,636 | SEC↗ |