CHMA

CHIASMA, INCCIK 1339469 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for CHMA PRO

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AI insights for CHMA

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Doyle John Brendan	Chief Financial Officer	2	$0	$0	2021-08-05
Giguere Lee	General Counsel	5	$0	$0	2021-08-05
KANNAN RAJ	Chief Executive Officer	9	$522.0K	$0	2021-08-05
LUDLAM WILLIAM	See Remarks	17	$32.9K	$0	2021-08-05
Enamait Drew	VP, Fin & Admin, PAO	12	$0	$0	2021-08-05
Varadan Anand	EVP, Chief Commerical Officer	9	$0	$0	2021-08-05
Geesaman Bard	Director	10	$0	$0	2021-08-05
Mamluk Roni	Director	53	$0	$1.36M	2021-08-05
Minick Scott	Director	23	$187.2K	$0	2021-08-05
Foley Todd	Director, 10% Owner	18	$0	$0	2021-08-05
STONEPINE CAPITAL, L.P.	10% Owner	1	$0	$0	2021-08-05
SCARLETT JOHN A	Director	11	$0	$0	2021-08-05
STACK DAVID M	Director	14	$106.7K	$0	2021-08-05
THERO JOHN F	Director	12	$0	$0	2021-08-05
Fitzpatrick Mark J.	President and CEO	9	$24.0K	$0	2020-12-04
TOBIN JAMES R	Director	2	$0	$0	2016-06-09
GADICKE ANSBERT	Director, 10% Owner	9	$0	$0	2016-06-09
Leuchtenberger Mark	CEO, President	1	$0	$0	2016-02-10
McCarthy Tara	General Counsel and Secretary	1	$0	$0	2016-02-01
Wertheimer Ruth	10% Owner	11	$1.50M	$0	2015-07-21
Scopa James Paul	10% Owner	8	$0	$0	2015-07-21
Abingworth LLP	10% Owner	10	$0	$0	2015-07-15
Miles Vincent J	Director, 10% Owner	10	$0	$0	2015-07-15

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Doyle John Brendan	Chief Financial Officer	D To issuer deriv	2021-08-05	2021-08-05	175,000	—	$0	0	SEC↗
Enamait Drew	VP, Fin & Admin, PAO	D To issuer deriv	2021-08-05	2021-08-05	11,843	—	$0	0	SEC↗
Enamait Drew	VP, Fin & Admin, PAO	D To issuer deriv	2021-08-05	2021-08-05	16,700	—	$0	0	SEC↗
Enamait Drew	VP, Fin & Admin, PAO	D To issuer deriv	2021-08-05	2021-08-05	33,807	—	$0	0	SEC↗
Enamait Drew	VP, Fin & Admin, PAO	D To issuer deriv	2021-08-05	2021-08-05	32,000	—	$0	0	SEC↗
Enamait Drew	VP, Fin & Admin, PAO	D To issuer deriv	2021-08-05	2021-08-05	55,000	—	$0	0	SEC↗
Enamait Drew	VP, Fin & Admin, PAO	D To issuer deriv	2021-08-05	2021-08-05	85,000	—	$0	0	SEC↗
Enamait Drew	VP, Fin & Admin, PAO	D To issuer deriv	2021-08-05	2021-08-05	65,000	—	$0	0	SEC↗
Foley Todd	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Foley Todd	Director	D To issuer deriv	2021-08-05	2021-08-05	10,000	—	$0	0	SEC↗
Foley Todd	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Foley Todd	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Foley Todd	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Geesaman Bard	Director	D To issuer deriv	2021-08-05	2021-08-05	1,145	—	$0	0	SEC↗
Geesaman Bard	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Geesaman Bard	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Geesaman Bard	Director	D To issuer deriv	2021-08-05	2021-08-05	1,145	—	$0	0	SEC↗
Geesaman Bard	Director	D To issuer deriv	2021-08-05	2021-08-05	880	—	$0	0	SEC↗
Giguere Lee	General Counsel	D To issuer deriv	2021-08-05	2021-08-05	100,000	—	$0	0	SEC↗
Giguere Lee	General Counsel	D To issuer deriv	2021-08-05	2021-08-05	90,000	—	$0	0	SEC↗
Giguere Lee	General Counsel	D To issuer deriv	2021-08-05	2021-08-05	75,000	—	$0	0	SEC↗
KANNAN RAJ	CEO and President	D To issuer deriv	2021-08-05	2021-08-05	950,000	—	$0	0	SEC↗
KANNAN RAJ	CEO and President	D To issuer deriv	2021-08-05	2021-08-05	250,000	—	$0	0	SEC↗
KANNAN RAJ	CEO and President	D To issuer deriv	2021-08-05	2021-08-05	300,000	—	$0	0	SEC↗
Varadan Anand	EVP, Chief Commerical Office	D To issuer deriv	2021-08-05	2021-08-05	105,000	—	$0	0	SEC↗
Varadan Anand	EVP, Chief Commerical Office	D To issuer deriv	2021-08-05	2021-08-05	425,000	—	$0	0	SEC↗
Varadan Anand	EVP, Chief Commerical Office	D To issuer deriv	2021-08-05	2021-08-05	112,441	—	$0	0	SEC↗
Varadan Anand	EVP, Chief Commerical Office	D To issuer deriv	2021-08-05	2021-08-05	36,069	—	$0	0	SEC↗
Varadan Anand	EVP, Chief Commerical Office	D To issuer deriv	2021-08-05	2021-08-05	13,692	—	$0	0	SEC↗
THERO JOHN F	Director	D To issuer deriv	2021-08-05	2021-08-05	20,000	—	$0	0	SEC↗
THERO JOHN F	Director	D To issuer deriv	2021-08-05	2021-08-05	10,000	—	$0	0	SEC↗
THERO JOHN F	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
THERO JOHN F	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
THERO JOHN F	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
THERO JOHN F	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
STACK DAVID M	Director	D To issuer deriv	2021-08-05	2021-08-05	10,000	—	$0	0	SEC↗
STACK DAVID M	Director	D To issuer deriv	2021-08-05	2021-08-05	72,683	—	$0	0	SEC↗
STACK DAVID M	Director	D To issuer deriv	2021-08-05	2021-08-05	91,954	—	$0	0	SEC↗
STACK DAVID M	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
STACK DAVID M	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
STACK DAVID M	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
STACK DAVID M	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
SCARLETT JOHN A	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
SCARLETT JOHN A	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
SCARLETT JOHN A	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
SCARLETT JOHN A	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
SCARLETT JOHN A	Director	D To issuer deriv	2021-08-05	2021-08-05	10,000	—	$0	0	SEC↗
Minick Scott	Director	D To issuer deriv	2021-08-05	2021-08-05	10,000	—	$0	0	SEC↗
Minick Scott	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Minick Scott	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Minick Scott	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Minick Scott	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Mamluk Roni	Director	D To issuer deriv	2021-08-05	2021-08-05	40,000	—	$0	0	SEC↗
Mamluk Roni	Director	D To issuer deriv	2021-08-05	2021-08-05	42,019	—	$0	0	SEC↗
Mamluk Roni	Director	D To issuer deriv	2021-08-05	2021-08-05	26,000	—	$0	0	SEC↗
Mamluk Roni	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Mamluk Roni	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Mamluk Roni	Director	D To issuer deriv	2021-08-05	2021-08-05	13,000	—	$0	0	SEC↗
Mamluk Roni	Director	D To issuer deriv	2021-08-05	2021-08-05	213,345	—	$0	0	SEC↗
Mamluk Roni	Director	D To issuer deriv	2021-08-05	2021-08-05	225,689	—	$0	0	SEC↗
LUDLAM WILLIAM	See Remarks	D To issuer deriv	2021-08-05	2021-08-05	45,916	—	$0	0	SEC↗
LUDLAM WILLIAM	See Remarks	D To issuer deriv	2021-08-05	2021-08-05	969	—	$0	0	SEC↗
LUDLAM WILLIAM	See Remarks	D To issuer deriv	2021-08-05	2021-08-05	14,531	—	$0	0	SEC↗
LUDLAM WILLIAM	See Remarks	D To issuer deriv	2021-08-05	2021-08-05	14,084	—	$0	0	SEC↗
LUDLAM WILLIAM	See Remarks	D To issuer deriv	2021-08-05	2021-08-05	52,011	—	$0	0	SEC↗
LUDLAM WILLIAM	See Remarks	D To issuer deriv	2021-08-05	2021-08-05	120,000	—	$0	0	SEC↗
LUDLAM WILLIAM	See Remarks	D To issuer deriv	2021-08-05	2021-08-05	65,000	—	$0	0	SEC↗
LUDLAM WILLIAM	See Remarks	D To issuer deriv	2021-08-05	2021-08-05	70,000	—	$0	0	SEC↗
LUDLAM WILLIAM	See Remarks	D To issuer deriv	2021-08-05	2021-08-05	18,189	—	$0	0	SEC↗
LUDLAM WILLIAM	See Remarks	D To issuer deriv	2021-08-05	2021-08-05	74,997	—	$0	0	SEC↗
LUDLAM WILLIAM	See Remarks	D To issuer deriv	2021-08-05	2021-08-05	25,003	—	$0	0	SEC↗
KANNAN RAJ	CEO and President	D To issuer	2021-08-05	2021-08-05	137,095	—	$0	0	SEC↗
STACK DAVID M	Director	D To issuer	2021-08-05	2021-08-05	25,000	—	$0	0	SEC↗
SCARLETT JOHN A	Director	D To issuer	2021-08-05	2021-08-05	61,322	—	$0	0	SEC↗
Minick Scott	Director	D To issuer	2021-08-05	2021-08-05	62,531	—	$0	0	SEC↗
Minick Scott	Director	D To issuer	2021-08-05	2021-08-05	87,194	—	$0	0	SEC↗
LUDLAM WILLIAM	See Remarks	D To issuer	2021-08-05	2021-08-05	11,799	—	$0	0	SEC↗
STONEPINE CAPITAL, L.P.	10% Owner	D To issuer	2021-08-05	2021-08-09	6,770,000	—	$0	0	SEC↗
Enamait Drew	VP, Fin & Admin, PAO	A Award deriv	2021-02-09	2021-02-11	85,000	—	$0	85,000	SEC↗
Giguere Lee	General Counsel	A Award deriv	2021-02-09	2021-02-11	90,000	—	$0	90,000	SEC↗
KANNAN RAJ	CEO and President	A Award deriv	2021-02-09	2021-02-11	300,000	—	$0	300,000	SEC↗
LUDLAM WILLIAM	See Remarks	A Award deriv	2021-02-09	2021-02-11	120,000	—	$0	120,000	SEC↗
Varadan Anand	EVP, Chief Commerical Office	A Award deriv	2021-02-09	2021-02-11	105,000	—	$0	105,000	SEC↗
Mamluk Roni	Director	M Exercise deriv	2021-02-09	2021-02-11	27,981	—	$0	42,019	SEC↗
Mamluk Roni	Director	S Sale	2021-02-09	2021-02-11	27,981	$5.00	$139.9K	0	SEC↗
Mamluk Roni	Director	M Exercise	2021-02-09	2021-02-11	27,981	$1.85	$51.8K	27,981	SEC↗
Doyle John Brendan	Chief Financial Officer	A Award deriv	2021-01-19	2021-01-20	175,000	—	$0	175,000	SEC↗
Fitzpatrick Mark J.	President	M Exercise deriv	2020-12-04	2020-12-07	10,000	—	$0	363,352	SEC↗
Fitzpatrick Mark J.	President	M Exercise	2020-12-04	2020-12-07	10,000	$2.60	$26.0K	19,612	SEC↗
STACK DAVID M	Director	P Buy	2020-11-30	2020-12-01	25,000	$4.27	$106.7K	25,000	SEC↗
KANNAN RAJ	Chief Executive Officer	P Buy	2020-11-23	2020-11-24	120,000	$4.00	$480.0K	137,095	SEC↗
KANNAN RAJ	Chief Executive Officer	P Buy	2020-07-14	2020-07-15	10,000	$4.20	$42.0K	17,095	SEC↗
Foley Todd	Director	A Award deriv	2020-06-11	2020-06-12	13,000	—	$0	13,000	SEC↗
Geesaman Bard	Director	A Award deriv	2020-06-11	2020-06-12	13,000	—	$0	13,000	SEC↗
Mamluk Roni	Director	A Award deriv	2020-06-11	2020-06-12	13,000	—	$0	13,000	SEC↗
Minick Scott	Director	A Award deriv	2020-06-11	2020-06-12	13,000	—	$0	13,000	SEC↗
STACK DAVID M	Director	A Award deriv	2020-06-11	2020-06-12	13,000	—	$0	13,000	SEC↗
THERO JOHN F	Director	A Award deriv	2020-06-11	2020-06-12	13,000	—	$0	13,000	SEC↗
SCARLETT JOHN A	Director	A Award deriv	2020-06-11	2020-06-12	13,000	—	$0	13,000	SEC↗
Varadan Anand	EVP, Chief Commerical Office	A Award deriv	2020-04-22	2020-04-22	425,000	—	$0	425,000	SEC↗
Mamluk Roni	Director	M Exercise	2020-02-20	2020-02-21	82,186	$0.09	$7.4K	82,186	SEC↗
Mamluk Roni	Director	S Sale	2020-02-20	2020-02-21	82,186	$4.54	$373.1K	0	SEC↗
KANNAN RAJ	Chief Executive Officer	A Award deriv	2020-02-14	2020-02-18	250,000	—	$0	250,000	SEC↗
Enamait Drew	VP, Fin & Admin, PAO	A Award deriv	2020-02-14	2020-02-18	55,000	—	$0	55,000	SEC↗
Giguere Lee	General Counsel	A Award deriv	2020-02-14	2020-02-18	75,000	—	$0	75,000	SEC↗
Fitzpatrick Mark J.	President	A Award deriv	2020-02-14	2020-02-18	150,000	—	$0	150,000	SEC↗
LUDLAM WILLIAM	See Remarks	A Award deriv	2020-02-14	2020-02-18	65,000	—	$0	65,000	SEC↗
Mamluk Roni	Director	M Exercise deriv	2019-12-20	2020-02-21	82,186	—	$0	0	SEC↗
Mamluk Roni	Director	M Exercise deriv	2019-12-20	2019-12-23	61,139	—	$0	0	SEC↗
Mamluk Roni	Director	S Sale	2019-12-20	2019-12-23	61,139	$5.51	$336.9K	0	SEC↗
Mamluk Roni	Director	M Exercise	2019-12-20	2019-12-23	61,139	$0.09	$5.5K	61,139	SEC↗
Mamluk Roni	Director	M Exercise deriv	2019-10-16	2019-10-17	10,000	—	$0	61,139	SEC↗
Mamluk Roni	Director	S Sale	2019-10-16	2019-10-17	10,000	$4.94	$49.4K	0	SEC↗
Mamluk Roni	Director	M Exercise	2019-10-16	2019-10-17	10,000	$0.09	$900	10,000	SEC↗
LUDLAM WILLIAM	See Remarks	P Buy	2019-09-27	2019-09-27	5,050	$4.91	$24.8K	11,799	SEC↗
Mamluk Roni	Director	M Exercise deriv	2019-09-20	2019-09-23	50,000	—	$0	71,139	SEC↗
Mamluk Roni	Director	S Sale	2019-09-20	2019-09-23	50,000	$5.59	$279.5K	0	SEC↗
Mamluk Roni	Director	M Exercise	2019-09-20	2019-09-23	50,000	$0.09	$4.5K	50,000	SEC↗
Minick Scott	Director	P Buy	2019-08-20	2019-08-21	5,518	$5.33	$29.4K	87,194	SEC↗
Minick Scott	Director	P Buy	2019-08-19	2019-08-21	4,300	$5.02	$21.6K	81,676	SEC↗
Mamluk Roni	Director	M Exercise deriv	2019-07-16	2019-07-17	10,000	—	$0	121,139	SEC↗
Mamluk Roni	Director	S Sale	2019-07-16	2019-07-17	10,000	$6.35	$63.5K	0	SEC↗
Mamluk Roni	Director	M Exercise	2019-07-16	2019-07-17	10,000	$0.09	$900	10,000	SEC↗
KANNAN RAJ	Chief Executive Officer	A Award deriv	2019-06-17	2019-06-17	950,000	—	$0	950,000	SEC↗
Foley Todd	Director	A Award deriv	2019-06-13	2019-06-17	13,000	—	$0	13,000	SEC↗
Geesaman Bard	Director	A Award deriv	2019-06-13	2019-06-17	13,000	—	$0	13,000	SEC↗
Mamluk Roni	Director	A Award deriv	2019-06-13	2019-06-17	13,000	—	$0	13,000	SEC↗
Minick Scott	Director	A Award deriv	2019-06-13	2019-06-17	13,000	—	$0	13,000	SEC↗
SCARLETT JOHN A	Director	A Award deriv	2019-06-13	2019-06-17	13,000	—	$0	13,000	SEC↗
STACK DAVID M	Director	A Award deriv	2019-06-13	2019-06-17	13,000	—	$0	13,000	SEC↗
THERO JOHN F	Director	A Award deriv	2019-06-13	2019-06-17	13,000	—	$0	13,000	SEC↗
Mamluk Roni	Director	M Exercise deriv	2019-04-16	2019-04-17	10,000	—	$0	131,139	SEC↗
Mamluk Roni	Director	M Exercise	2019-04-16	2019-04-17	10,000	$0.09	$900	10,000	SEC↗
Mamluk Roni	Director	S Sale	2019-04-16	2019-04-17	10,000	$5.31	$53.1K	0	SEC↗
LUDLAM WILLIAM	See Remarks	P Buy	2019-04-01	2019-04-02	1,625	$5.00	$8.1K	6,749	SEC↗
Mamluk Roni	Director	M Exercise deriv	2019-03-05	2019-03-06	5,000	—	$0	141,139	SEC↗
Mamluk Roni	Director	S Sale	2019-03-05	2019-03-06	5,000	$5.00	$25.0K	0	SEC↗
Mamluk Roni	Director	M Exercise	2019-03-05	2019-03-06	5,000	$0.09	$450	5,000	SEC↗
Enamait Drew	VP, Fin & Admin, PAO	A Award deriv	2019-02-14	2019-02-15	32,000	—	$0	32,000	SEC↗
Fitzpatrick Mark J.	President and CEO	A Award deriv	2019-02-14	2019-02-15	186,000	—	$0	186,000	SEC↗
LUDLAM WILLIAM	See Remarks	A Award deriv	2019-02-14	2019-02-15	70,000	—	$0	70,000	SEC↗
Mamluk Roni	Director	M Exercise deriv	2019-01-22	2019-01-23	5,000	—	$0	146,139	SEC↗
Mamluk Roni	Director	M Exercise	2019-01-22	2019-01-23	5,000	$0.09	$450	5,000	SEC↗
Mamluk Roni	Director	S Sale	2019-01-22	2019-01-23	5,000	$3.67	$18.4K	0	SEC↗
Fitzpatrick Mark J.	President and CEO	P Buy	2018-12-20	2018-12-21	9,612	$2.50	$24.0K	9,612	SEC↗
Minick Scott	Director	P Buy	2018-09-20	2018-09-20	13,000	$3.09	$40.2K	84,220	SEC↗
Minick Scott	Director	P Buy	2018-09-19	2018-09-20	8,000	$3.06	$24.5K	71,220	SEC↗
Minick Scott	Director	P Buy	2018-09-18	2018-09-20	4,000	$3.07	$12.3K	63,220	SEC↗
Mamluk Roni	Director	M Exercise deriv	2018-06-18	2018-06-20	2,389	—	$0	0	SEC↗
Mamluk Roni	Director	M Exercise	2018-06-18	2018-06-20	2,389	$0.09	$215	2,389	SEC↗
Mamluk Roni	Director	S Sale	2018-06-18	2018-06-20	2,389	$1.46	$3.5K	0	SEC↗
Foley Todd	Director	A Award deriv	2018-06-07	2018-06-11	13,000	—	$0	13,000	SEC↗
Geesaman Bard	Director	A Award deriv	2018-06-07	2018-06-11	13,000	—	$0	13,000	SEC↗
Mamluk Roni	Director	A Award deriv	2018-06-07	2018-06-11	13,000	—	$0	13,000	SEC↗
SCARLETT JOHN A	Director	A Award deriv	2018-06-07	2018-06-11	13,000	—	$0	13,000	SEC↗
STACK DAVID M	Director	A Award deriv	2018-06-07	2018-06-11	13,000	—	$0	13,000	SEC↗
THERO JOHN F	Director	A Award deriv	2018-06-07	2018-06-11	13,000	—	$0	13,000	SEC↗
Minick Scott	Director	A Award deriv	2018-06-07	2018-06-11	13,000	—	$0	13,000	SEC↗
Mamluk Roni	Director	M Exercise deriv	2018-03-19	2018-03-20	2,389	—	$0	2,389	SEC↗
Mamluk Roni	Director	M Exercise	2018-03-19	2018-03-20	2,389	$0.09	$215	2,389	SEC↗
Mamluk Roni	Director	S Sale	2018-03-19	2018-03-20	2,389	$1.53	$3.7K	0	SEC↗
Fitzpatrick Mark J.	President and CEO	A Award deriv	2018-02-23	2018-02-26	67,967	—	$0	67,967	SEC↗
Fitzpatrick Mark J.	President and CEO	A Award deriv	2018-02-23	2018-02-26	194,183	—	$0	194,183	SEC↗
Enamait Drew	VP, Fin & Admin, PAO	A Award deriv	2018-02-23	2018-02-26	11,843	—	$0	11,843	SEC↗
Enamait Drew	VP, Fin & Admin, PAO	A Award deriv	2018-02-23	2018-02-26	33,807	—	$0	33,807	SEC↗
Mamluk Roni	Director	M Exercise deriv	2017-12-18	2017-12-19	2,389	—	$0	4,778	SEC↗
Mamluk Roni	Director	M Exercise	2017-12-18	2017-12-19	2,389	$0.09	$215	2,389	SEC↗
Mamluk Roni	Director	S Sale	2017-12-18	2017-12-19	2,389	$1.75	$4.2K	0	SEC↗
Mamluk Roni	Director	M Exercise deriv	2017-10-24	2017-10-26	2,389	—	$0	7,167	SEC↗
Mamluk Roni	Director	M Exercise	2017-10-24	2017-10-26	2,389	$0.09	$215	2,389	SEC↗
Mamluk Roni	Director	S Sale	2017-10-24	2017-10-26	2,389	$2.27	$5.4K	0	SEC↗
Minick Scott	Director	P Buy	2017-09-21	2017-09-22	10,000	$2.36	$23.6K	59,220	SEC↗
Minick Scott	Director	P Buy	2017-09-20	2017-09-22	15,000	$2.38	$35.7K	49,220	SEC↗
THERO JOHN F	Director	A Award deriv	2017-06-15	2017-06-19	13,000	—	$0	13,000	SEC↗
SCARLETT JOHN A	Director	A Award deriv	2017-06-15	2017-06-19	13,000	—	$0	13,000	SEC↗
Minick Scott	Director	A Award deriv	2017-06-15	2017-06-19	13,000	—	$0	13,000	SEC↗
Geesaman Bard	Director	A Award deriv	2017-06-15	2017-06-19	13,000	—	$0	13,000	SEC↗
Foley Todd	Director	A Award deriv	2017-06-15	2017-06-19	13,000	—	$0	13,000	SEC↗
Mamluk Roni	Director	A Award deriv	2017-06-15	2017-06-19	26,000	—	$0	26,000	SEC↗
STACK DAVID M	Director	A Award deriv	2017-06-15	2017-06-19	13,000	—	$0	13,000	SEC↗
Mamluk Roni	Chief Development Officer	A Award deriv	2016-12-14	2016-12-16	70,000	—	$0	70,000	SEC↗
Fitzpatrick Mark J.	President and CEO	A Award deriv	2016-10-25	2016-10-25	373,352	—	$0	373,352	SEC↗
SCARLETT JOHN A	Director	A Award deriv	2016-06-09	2016-06-13	10,000	—	$0	10,000	SEC↗
THERO JOHN F	Director	A Award deriv	2016-06-09	2016-06-13	10,000	—	$0	10,000	SEC↗
TOBIN JAMES R	Director	A Award deriv	2016-06-09	2016-06-13	10,000	—	$0	10,000	SEC↗
Minick Scott	Director	A Award deriv	2016-06-09	2016-06-13	10,000	—	$0	10,000	SEC↗
Geesaman Bard	Director	A Award deriv	2016-06-09	2016-06-13	10,000	—	$0	10,000	SEC↗
STACK DAVID M	Director	A Award deriv	2016-06-09	2016-06-13	10,000	—	$0	10,000	SEC↗
GADICKE ANSBERT	Director	A Award deriv	2016-06-09	2016-06-13	10,000	—	$0	10,000	SEC↗
Foley Todd	Director	A Award deriv	2016-06-09	2016-06-13	10,000	—	$0	10,000	SEC↗
Varadan Anand	Chief Commercial Officer	A Award deriv	2016-02-10	2016-02-12	140,000	—	$0	140,000	SEC↗
Leuchtenberger Mark	CEO, President	A Award deriv	2016-02-10	2016-02-12	125,000	—	$0	125,000	SEC↗
Mamluk Roni	Chief Development Officer	A Award deriv	2016-02-10	2016-02-12	40,000	—	$0	40,000	SEC↗
Fitzpatrick Mark J.	CFO, Treasurer	A Award deriv	2016-02-10	2016-02-12	70,000	—	$0	70,000	SEC↗
McCarthy Tara	General Counsel and Secretar	A Award deriv	2016-02-01	2016-02-01	200,000	$10.06	$2.01M	200,000	SEC↗
THERO JOHN F	Director	A Award deriv	2015-12-10	2015-12-11	20,000	—	$0	20,000	SEC↗
TOBIN JAMES R	Director	A Award deriv	2015-12-10	2015-12-11	20,000	—	$0	20,000	SEC↗
Varadan Anand	Chief Commercial Officer	A Award deriv	2015-08-17	2015-08-19	280,000	$27.72	$7.76M	280,000	SEC↗
Scopa James Paul	10% Owner	C Conversion deriv	2015-07-21	2015-07-21	95,225	—	$0	0	SEC↗
Scopa James Paul	10% Owner	C Conversion deriv	2015-07-21	2015-07-21	13,000,000	—	$0	0	SEC↗
Scopa James Paul	10% Owner	C Conversion deriv	2015-07-21	2015-07-21	22,721,988	—	$0	0	SEC↗
Scopa James Paul	10% Owner	C Conversion deriv	2015-07-21	2015-07-21	16,066,669	—	$0	0	SEC↗
Foley Todd	Director, 10% Owner	C Conversion deriv	2015-07-21	2015-07-21	22,721,988	—	$0	0	SEC↗
Foley Todd	Director, 10% Owner	C Conversion deriv	2015-07-21	2015-07-21	16,066,669	—	$0	0	SEC↗
Foley Todd	Director, 10% Owner	C Conversion deriv	2015-07-21	2015-07-21	13,000,000	—	$0	0	SEC↗
Foley Todd	Director, 10% Owner	C Conversion deriv	2015-07-21	2015-07-21	95,225	—	$0	0	SEC↗
GADICKE ANSBERT	Director, 10% Owner	C Conversion deriv	2015-07-21	2015-07-21	16,066,669	—	$0	0	SEC↗
GADICKE ANSBERT	Director, 10% Owner	C Conversion deriv	2015-07-21	2015-07-21	13,000,000	—	$0	0	SEC↗
GADICKE ANSBERT	Director, 10% Owner	C Conversion deriv	2015-07-21	2015-07-21	22,721,988	—	$0	0	SEC↗
GADICKE ANSBERT	Director, 10% Owner	C Conversion deriv	2015-07-21	2015-07-21	95,225	—	$0	0	SEC↗
Minick Scott	Director	C Conversion deriv	2015-07-21	2015-07-22	11,041	—	$0	0	SEC↗
Minick Scott	Director	C Conversion deriv	2015-07-21	2015-07-22	250,000	—	$0	0	SEC↗
Wertheimer Ruth	10% Owner	C Conversion deriv	2015-07-21	2015-07-23	2,500,000	—	$0	0	SEC↗
Wertheimer Ruth	10% Owner	C Conversion deriv	2015-07-21	2015-07-23	3,000,000	—	$0	0	SEC↗
Wertheimer Ruth	10% Owner	C Conversion deriv	2015-07-21	2015-07-23	4,700,000	—	$0	0	SEC↗
Wertheimer Ruth	10% Owner	C Conversion deriv	2015-07-21	2015-07-23	112,665	—	$0	0	SEC↗
Wertheimer Ruth	10% Owner	C Conversion deriv	2015-07-21	2015-07-23	6,946,314	—	$0	0	SEC↗
Scopa James Paul	10% Owner	C Conversion	2015-07-21	2015-07-21	10,426	—	$0	10,426	SEC↗
Scopa James Paul	10% Owner	C Conversion	2015-07-21	2015-07-21	2,488,171	—	$0	2,498,597	SEC↗
Scopa James Paul	10% Owner	C Conversion	2015-07-21	2015-07-21	1,423,566	—	$0	5,681,544	SEC↗
Scopa James Paul	10% Owner	C Conversion	2015-07-21	2015-07-21	1,759,381	—	$0	4,257,978	SEC↗
Foley Todd	Director, 10% Owner	C Conversion	2015-07-21	2015-07-21	10,426	—	$0	10,426	SEC↗
Foley Todd	Director, 10% Owner	C Conversion	2015-07-21	2015-07-21	2,488,171	—	$0	2,498,597	SEC↗
Foley Todd	Director, 10% Owner	C Conversion	2015-07-21	2015-07-21	1,759,381	—	$0	4,257,978	SEC↗
Foley Todd	Director, 10% Owner	C Conversion	2015-07-21	2015-07-21	1,423,566	—	$0	5,681,544	SEC↗
GADICKE ANSBERT	Director, 10% Owner	C Conversion	2015-07-21	2015-07-21	2,488,171	—	$0	2,498,597	SEC↗
GADICKE ANSBERT	Director, 10% Owner	C Conversion	2015-07-21	2015-07-21	10,426	—	$0	10,426	SEC↗
GADICKE ANSBERT	Director, 10% Owner	C Conversion	2015-07-21	2015-07-21	1,423,566	—	$0	5,681,544	SEC↗
GADICKE ANSBERT	Director, 10% Owner	C Conversion	2015-07-21	2015-07-21	1,759,381	—	$0	4,257,978	SEC↗
Minick Scott	Director	C Conversion	2015-07-21	2015-07-22	27,376	—	$0	96,751	SEC↗
Minick Scott	Director	C Conversion	2015-07-21	2015-07-22	1,209	—	$0	69,375	SEC↗
Wertheimer Ruth	10% Owner	C Conversion	2015-07-21	2015-07-23	12,337	—	$0	12,337	SEC↗
Wertheimer Ruth	10% Owner	C Conversion	2015-07-21	2015-07-23	760,656	—	$0	772,993	SEC↗
Wertheimer Ruth	10% Owner	C Conversion	2015-07-21	2015-07-23	514,674	—	$0	1,287,667	SEC↗
Wertheimer Ruth	10% Owner	C Conversion	2015-07-21	2015-07-23	328,515	—	$0	1,616,182	SEC↗
Wertheimer Ruth	10% Owner	C Conversion	2015-07-21	2015-07-23	273,762	—	$0	273,762	SEC↗
Wertheimer Ruth	10% Owner	P Buy	2015-07-21	2015-07-23	93,750	$16.00	$1.50M	93,750	SEC↗
Abingworth LLP	10% Owner	C Conversion deriv	2015-07-15	2016-03-09	1,642,575	—	$0	0	SEC↗
Abingworth LLP	10% Owner	J Other deriv	2015-07-15	2016-03-09	109,504	—	$0	109,504	SEC↗
Abingworth LLP	10% Owner	J Other deriv	2015-07-15	2016-03-09	410,642	—	$0	410,642	SEC↗
Abingworth LLP	10% Owner	C Conversion deriv	2015-07-15	2016-03-09	438,020	—	$0	0	SEC↗
Miles Vincent J	Director, 10% Owner	C Conversion deriv	2015-07-15	2016-03-09	1,642,575	—	$0	0	SEC↗
Miles Vincent J	Director, 10% Owner	J Other deriv	2015-07-15	2016-03-09	109,504	—	$0	109,504	SEC↗
Miles Vincent J	Director, 10% Owner	C Conversion deriv	2015-07-15	2016-03-09	438,020	—	$0	0	SEC↗
Miles Vincent J	Director, 10% Owner	J Other deriv	2015-07-15	2016-03-09	410,642	—	$0	410,642	SEC↗
Abingworth LLP	10% Owner	C Conversion	2015-07-15	2016-03-09	2,080,595	—	$0	2,080,595	SEC↗
Miles Vincent J	Director, 10% Owner	C Conversion	2015-07-15	2016-03-09	2,080,595	—	$0	2,080,595	SEC↗
Abingworth LLP	10% Owner	C Conversion deriv	2015-07-15	2015-07-17	109,504	—	$0	0	SEC↗
Abingworth LLP	10% Owner	C Conversion deriv	2015-07-15	2015-07-17	410,642	—	$0	0	SEC↗
Abingworth LLP	10% Owner	C Conversion deriv	2015-07-15	2015-07-17	1,642,575	—	$0	0	SEC↗
Abingworth LLP	10% Owner	C Conversion deriv	2015-07-15	2015-07-17	438,020	—	$0	0	SEC↗
Miles Vincent J	Director, 10% Owner	C Conversion deriv	2015-07-15	2015-07-17	410,642	—	$0	0	SEC↗
Miles Vincent J	Director, 10% Owner	C Conversion deriv	2015-07-15	2015-07-17	1,642,575	—	$0	0	SEC↗
Miles Vincent J	Director, 10% Owner	C Conversion deriv	2015-07-15	2015-07-17	109,504	—	$0	0	SEC↗
Miles Vincent J	Director, 10% Owner	C Conversion deriv	2015-07-15	2015-07-17	438,020	—	$0	0	SEC↗
Abingworth LLP	10% Owner	C Conversion	2015-07-15	2015-07-17	2,600,741	—	$0	2,600,741	SEC↗
Miles Vincent J	Director, 10% Owner	C Conversion	2015-07-15	2015-07-17	2,600,741	—	$0	2,600,741	SEC↗