CNST

CONSTELLATION PHARMACEUTICALS INCCIK 1434418 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for CNST PRO

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AI insights for CNST

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Humphrey Jeffrey	Chief Medical Officer	4	$0	$0	2021-07-15
Trojer Patrick	Chief Scientific Officer	55	$0	$1.78M	2021-07-15
Audia James E	Director	23	$0	$1.17M	2021-07-15
Raythatha Jigar	See Remarks	27	$0	$3.37M	2021-07-15
Trehu Elizabeth	Director	8	$0	$0	2021-07-15
Reeve Emma	Chief Financial Officer	88	$0	$4.16M	2021-07-15
Braunstein Scott	Director	6	$0	$0	2021-07-15
Hoerter Steven L.	Director	9	$0	$0	2021-07-15
Levy Richard S	Director	4	$0	$0	2021-07-15
Valentine Karen	See Remarks	64	$0	$3.30M	2021-07-15
GOLDSMITH MARK A	Director, 10% Owner	41	$0	$1.02M	2021-07-15
Ponoi II Management, LLC	10% Owner	11	$0	$369.5K	2021-02-17
Svennilson Peter	Director, 10% Owner	10	$0	$369.5K	2021-02-17
COLUMN GROUP III GP, LP	10% Owner	4	$936.9K	$0	2020-12-14
Senderowicz Adrian	Chief Medical Officer	16	$0	$1.24M	2020-05-12
GOEDDEL DAVID V	10% Owner	2	$936.9K	$0	2020-03-20
Venrock Healthcare Capital Partners II, L.P.	10% Owner	1	$13.80M	$0	2019-12-13
EVNIN ANTHONY B	Director, 10% Owner	11	$39.80M	$0	2019-12-13
REGENTS OF THE UNIVERSITY OF CALIFORNIA	10% Owner	11	$2.00M	$38.64M	2019-11-12
COLUMN GROUP GP, LP	10% Owner	2	$12.00M	$0	2019-10-03
TEPPER ROBERT I	Director, 10% Owner	11	$4.00M	$0	2019-06-06
STARR KEVIN P	10% Owner	2	$0	$0	2018-08-22
CASDIN VENTURE OPPORTUNITIES FUND GP, LLC	10% Owner	7	$4.00M	$0	2018-07-23
Precision Onco Ltd	10% Owner	2	$0	$0	2018-07-23
Mountain Berg Ltd	10% Owner	4	$0	$0	2018-07-23
Spur Ventures II, LP	10% Owner	4	$0	$0	2018-07-23
Topspin Biotech Fund II, L.P.	10% Owner	10	$0	$0	2018-07-23
Alexandria Venture Investments, LLC	10% Owner	7	$1.00M	$0	2018-07-23
THIRD ROCK VENTURES LP	10% Owner	8	$4.00M	$0	2018-07-23
Flynn James E	10% Owner	3	$3.00M	$0	2018-07-23
ORBIMED ADVISORS LLC	10% Owner	6	$3.00M	$0	2018-07-23

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Levy Richard S	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
Levy Richard S	Director	D To issuer deriv	2021-07-15	2021-07-19	26,342	—	$0	0	SEC↗
Audia James E	Director	D To issuer deriv	2021-07-15	2021-07-19	9,083	—	$0	0	SEC↗
Audia James E	Director	D To issuer deriv	2021-07-15	2021-07-19	11,626	—	$0	0	SEC↗
Audia James E	Director	D To issuer deriv	2021-07-15	2021-07-19	9,083	—	$0	0	SEC↗
Audia James E	Director	D To issuer deriv	2021-07-15	2021-07-19	2,384	—	$0	0	SEC↗
Audia James E	Director	D To issuer deriv	2021-07-15	2021-07-19	24,604	—	$0	0	SEC↗
Audia James E	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
Audia James E	Director	D To issuer deriv	2021-07-15	2021-07-19	1,277	—	$0	0	SEC↗
Audia James E	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
Audia James E	Director	D To issuer deriv	2021-07-15	2021-07-19	8,175	—	$0	0	SEC↗
Audia James E	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
Braunstein Scott	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
Braunstein Scott	Director	D To issuer deriv	2021-07-15	2021-07-19	26,342	—	$0	0	SEC↗
Braunstein Scott	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
GOLDSMITH MARK A	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
GOLDSMITH MARK A	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
GOLDSMITH MARK A	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
GOLDSMITH MARK A	Director	D To issuer deriv	2021-07-15	2021-07-19	12,446	—	$0	0	SEC↗
GOLDSMITH MARK A	Director	D To issuer deriv	2021-07-15	2021-07-19	9,083	—	$0	0	SEC↗
GOLDSMITH MARK A	Director	D To issuer deriv	2021-07-15	2021-07-19	6,825	—	$0	0	SEC↗
Hoerter Steven L.	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
Hoerter Steven L.	Director	D To issuer deriv	2021-07-15	2021-07-19	26,342	—	$0	0	SEC↗
Hoerter Steven L.	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
Hoerter Steven L.	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
Raythatha Jigar	See Remarks	D To issuer deriv	2021-07-15	2021-07-19	141,929	—	$0	0	SEC↗
Raythatha Jigar	See Remarks	D To issuer deriv	2021-07-15	2021-07-19	423,940	—	$0	0	SEC↗
Raythatha Jigar	See Remarks	D To issuer deriv	2021-07-15	2021-07-19	141,929	—	$0	0	SEC↗
Raythatha Jigar	See Remarks	D To issuer deriv	2021-07-15	2021-07-19	204,500	—	$0	0	SEC↗
Raythatha Jigar	See Remarks	D To issuer deriv	2021-07-15	2021-07-19	245,000	—	$0	0	SEC↗
Raythatha Jigar	See Remarks	D To issuer deriv	2021-07-15	2021-07-19	306,938	—	$0	0	SEC↗
Raythatha Jigar	See Remarks	D To issuer deriv	2021-07-15	2021-07-19	200,000	—	$0	0	SEC↗
Reeve Emma	Chief Financial Officer	D To issuer deriv	2021-07-15	2021-07-19	17,666	—	$0	0	SEC↗
Reeve Emma	Chief Financial Officer	D To issuer deriv	2021-07-15	2021-07-19	60,000	—	$0	0	SEC↗
Reeve Emma	Chief Financial Officer	D To issuer deriv	2021-07-15	2021-07-19	37,527	—	$0	0	SEC↗
Reeve Emma	Chief Financial Officer	D To issuer deriv	2021-07-15	2021-07-19	73,428	—	$0	0	SEC↗
Reeve Emma	Chief Financial Officer	D To issuer deriv	2021-07-15	2021-07-19	66,950	—	$0	0	SEC↗
Reeve Emma	Chief Financial Officer	D To issuer deriv	2021-07-15	2021-07-19	80,971	—	$0	0	SEC↗
Reeve Emma	Chief Financial Officer	D To issuer deriv	2021-07-15	2021-07-19	11,777	—	$0	0	SEC↗
Trojer Patrick	Chief Scientific Officer	D To issuer deriv	2021-07-15	2021-07-19	22,708	—	$0	0	SEC↗
Trojer Patrick	Chief Scientific Officer	D To issuer deriv	2021-07-15	2021-07-19	33,330	—	$0	0	SEC↗
Trojer Patrick	Chief Scientific Officer	D To issuer deriv	2021-07-15	2021-07-19	40,000	—	$0	0	SEC↗
Trojer Patrick	Chief Scientific Officer	D To issuer deriv	2021-07-15	2021-07-19	17,312	—	$0	0	SEC↗
Trojer Patrick	Chief Scientific Officer	D To issuer deriv	2021-07-15	2021-07-19	78,000	—	$0	0	SEC↗
Trojer Patrick	Chief Scientific Officer	D To issuer deriv	2021-07-15	2021-07-19	850	—	$0	0	SEC↗
Trojer Patrick	Chief Scientific Officer	D To issuer deriv	2021-07-15	2021-07-19	72,050	—	$0	0	SEC↗
Trojer Patrick	Chief Scientific Officer	D To issuer deriv	2021-07-15	2021-07-19	43,387	—	$0	0	SEC↗
Trojer Patrick	Chief Scientific Officer	D To issuer deriv	2021-07-15	2021-07-19	55,000	—	$0	0	SEC↗
Trojer Patrick	Chief Scientific Officer	D To issuer deriv	2021-07-15	2021-07-19	3,121	—	$0	0	SEC↗
Trehu Elizabeth	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
Trehu Elizabeth	Director	D To issuer deriv	2021-07-15	2021-07-19	26,342	—	$0	0	SEC↗
Trehu Elizabeth	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
Trehu Elizabeth	Director	D To issuer deriv	2021-07-15	2021-07-19	13,171	—	$0	0	SEC↗
Valentine Karen	See Remarks	D To issuer deriv	2021-07-15	2021-07-19	81,939	—	$0	0	SEC↗
Valentine Karen	See Remarks	D To issuer deriv	2021-07-15	2021-07-19	22,425	—	$0	0	SEC↗
Valentine Karen	See Remarks	D To issuer deriv	2021-07-15	2021-07-19	41,800	—	$0	0	SEC↗
Valentine Karen	See Remarks	D To issuer deriv	2021-07-15	2021-07-19	58,600	—	$0	0	SEC↗
Humphrey Jeffrey	Chief Medical Officer	D To issuer deriv	2021-07-15	2021-07-19	35,055	—	$0	0	SEC↗
Humphrey Jeffrey	Chief Medical Officer	D To issuer deriv	2021-07-15	2021-07-19	133,000	—	$0	0	SEC↗
Hoerter Steven L.	Director	D To issuer deriv	2021-07-15	2021-07-23	26,342	—	$0	0	SEC↗
Audia James E	Director	D To issuer	2021-07-15	2021-07-19	25,434	—	$0	0	SEC↗
GOLDSMITH MARK A	Director	D To issuer	2021-07-15	2021-07-19	89,857	—	$0	0	SEC↗
Raythatha Jigar	See Remarks	D To issuer	2021-07-15	2021-07-19	14,961	—	$0	0	SEC↗
Audia James E	Director	A Award deriv	2021-06-02	2021-06-04	13,171	—	$0	13,171	SEC↗
Hoerter Steven L.	Director	A Award deriv	2021-06-02	2021-06-04	13,171	—	$0	13,171	SEC↗
Trehu Elizabeth	Director	A Award deriv	2021-06-02	2021-06-04	13,171	—	$0	13,171	SEC↗
GOLDSMITH MARK A	Director	A Award deriv	2021-06-02	2021-06-04	13,171	—	$0	13,171	SEC↗
Braunstein Scott	Director	A Award deriv	2021-06-02	2021-06-04	13,171	—	$0	13,171	SEC↗
Levy Richard S	Director	A Award deriv	2021-06-02	2021-06-04	13,171	—	$0	13,171	SEC↗
GOLDSMITH MARK A	Director	M Exercise deriv	2021-03-04	2021-03-08	14,987	—	$0	0	SEC↗
GOLDSMITH MARK A	Director	M Exercise	2021-03-04	2021-03-08	14,987	—	$0	14,987	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2021-02-22	2021-02-23	6,260	—	$0	11,777	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2021-02-22	2021-02-23	6,260	$37.60	$235.4K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2021-02-22	2021-02-23	6,260	$8.04	$50.3K	6,260	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2021-02-19	2021-02-23	4,010	—	$0	18,037	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2021-02-19	2021-02-23	4,010	$8.04	$32.2K	4,010	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2021-02-19	2021-02-23	4,010	$37.71	$151.2K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2021-02-18	2021-02-19	1,100	—	$0	22,047	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2021-02-18	2021-02-19	1,100	$8.04	$8.8K	1,100	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2021-02-18	2021-02-19	1,100	$37.58	$41.3K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2021-02-17	2021-02-19	410	—	$0	23,147	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2021-02-17	2021-02-19	410	$8.04	$3.3K	410	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2021-02-17	2021-02-19	410	$37.56	$15.4K	0	SEC↗
Ponoi II Management, LLC	10% Owner	S Sale	2021-02-17	2021-02-19	10,000	$36.95	$369.5K	99,155	SEC↗
Svennilson Peter	10% Owner	S Sale	2021-02-17	2021-02-19	10,000	$36.95	$369.5K	99,155	SEC↗
Reeve Emma	Chief Financial Officer	A Award deriv	2021-02-16	2021-02-18	66,950	—	$0	66,950	SEC↗
Trojer Patrick	Chief Scientific Officer	A Award deriv	2021-02-16	2021-02-18	72,050	—	$0	72,050	SEC↗
Valentine Karen	See Remarks	A Award deriv	2021-02-16	2021-02-18	58,600	—	$0	58,600	SEC↗
Raythatha Jigar	See Remarks	A Award deriv	2021-02-16	2021-02-18	204,500	—	$0	204,500	SEC↗
Humphrey Jeffrey	Chief Medical Officer	A Award deriv	2021-02-16	2021-02-18	35,055	—	$0	35,055	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2021-01-19	2021-01-20	17,203	—	$0	81,939	SEC↗
Valentine Karen	See Remarks	S Sale	2021-01-19	2021-01-20	7,203	$35.11	$252.9K	0	SEC↗
Valentine Karen	See Remarks	S Sale	2021-01-19	2021-01-20	1,227	$33.69	$41.3K	7,203	SEC↗
Valentine Karen	See Remarks	M Exercise	2021-01-19	2021-01-20	17,203	$11.50	$197.8K	17,203	SEC↗
Valentine Karen	See Remarks	S Sale	2021-01-19	2021-01-20	8,773	$33.08	$290.2K	8,430	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-12-21	2020-12-22	4,542	—	$0	80,971	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-12-21	2020-12-22	1,178	—	$0	17,666	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-12-21	2020-12-22	4,542	$6.61	$30.0K	5,720	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-12-21	2020-12-22	5,720	$35.11	$200.8K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-12-21	2020-12-22	1,178	$7.60	$9.0K	1,178	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	S Sale	2020-12-21	2020-12-28	4,020	$35.02	$140.8K	139,043	SEC↗
COLUMN GROUP III GP, LP	10% Owner	X Exercise deriv	2020-12-14	2020-12-16	30,107	—	$0	0	SEC↗
Svennilson Peter	10% Owner	X Exercise deriv	2020-12-14	2020-12-16	30,107	—	$0	0	SEC↗
COLUMN GROUP III GP, LP	10% Owner	X Exercise	2020-12-14	2020-12-16	30,107	$1.55	$46.7K	2,584,957	SEC↗
Svennilson Peter	10% Owner	X Exercise	2020-12-14	2020-12-16	30,107	$1.55	$46.7K	2,584,957	SEC↗
Humphrey Jeffrey	Chief Medical Officer	A Award deriv	2020-07-07	2020-07-08	133,000	—	$0	133,000	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-06-08	2020-06-10	589	—	$0	18,844	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-06-08	2020-06-10	233	$38.35	$8.9K	0	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-06-08	2020-06-10	144	$37.67	$5.4K	233	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-06-08	2020-06-10	589	$7.60	$4.5K	589	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-06-08	2020-06-10	212	$36.59	$7.8K	377	SEC↗
Braunstein Scott	Director	A Award deriv	2020-06-04	2020-06-08	13,171	—	$0	13,171	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	A Award deriv	2020-06-04	2020-06-08	13,171	—	$0	13,171	SEC↗
Audia James E	Director	A Award deriv	2020-06-04	2020-06-08	13,171	—	$0	13,171	SEC↗
Hoerter Steven L.	Director	A Award deriv	2020-06-04	2020-06-08	13,171	—	$0	13,171	SEC↗
Trehu Elizabeth	Director	A Award deriv	2020-06-04	2020-06-08	13,171	—	$0	13,171	SEC↗
Raythatha Jigar	See Remarks	M Exercise deriv	2020-05-12	2020-05-13	9,209	—	$0	423,940	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise deriv	2020-05-12	2020-05-13	1,300	—	$0	12,446	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise deriv	2020-05-12	2020-05-13	300	—	$0	6,825	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise deriv	2020-05-12	2020-05-13	2,625	—	$0	14,987	SEC↗
Senderowicz Adrian	Chief Medical Officer	M Exercise deriv	2020-05-12	2020-05-13	9,357	—	$0	99,663	SEC↗
Raythatha Jigar	See Remarks	M Exercise	2020-05-12	2020-05-13	9,209	$5.51	$50.7K	24,170	SEC↗
Raythatha Jigar	See Remarks	S Sale	2020-05-12	2020-05-13	9,209	$50.17	$462.0K	14,961	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise	2020-05-12	2020-05-13	1,300	$7.60	$9.9K	147,288	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise	2020-05-12	2020-05-13	2,625	$1.55	$4.1K	145,688	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise	2020-05-12	2020-05-13	300	$11.50	$3.5K	145,988	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	S Sale	2020-05-12	2020-05-13	4,225	$50.05	$211.5K	143,063	SEC↗
Senderowicz Adrian	Chief Medical Officer	M Exercise	2020-05-12	2020-05-13	9,357	$5.51	$51.6K	25,241	SEC↗
Senderowicz Adrian	Chief Medical Officer	S Sale	2020-05-12	2020-05-13	9,357	$50.18	$469.5K	15,884	SEC↗
Audia James E	Director	S Sale	2020-05-12	2020-05-13	6,100	$50.10	$305.6K	25,434	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-05-11	2020-05-12	10,736	—	$0	73,428	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-05-11	2020-05-12	1,178	—	$0	19,433	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-05-11	2020-05-12	2,628	—	$0	37,527	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-05-11	2020-05-12	1,520	—	$0	85,513	SEC↗
Raythatha Jigar	See Remarks	M Exercise deriv	2020-05-11	2020-05-13	26	—	$0	433,149	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise deriv	2020-05-11	2020-05-13	100	—	$0	17,612	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-05-11	2020-05-12	16,062	$49.53	$795.6K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-05-11	2020-05-12	1,520	$6.61	$10.0K	16,062	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-05-11	2020-05-12	1,178	$7.60	$9.0K	14,542	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-05-11	2020-05-12	10,736	$8.76	$94.0K	13,364	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-05-11	2020-05-12	2,628	$11.50	$30.2K	2,628	SEC↗
Raythatha Jigar	See Remarks	M Exercise	2020-05-11	2020-05-13	26	$5.51	$143	14,987	SEC↗
Raythatha Jigar	See Remarks	S Sale	2020-05-11	2020-05-13	26	$50.00	$1.3K	14,961	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise	2020-05-11	2020-05-13	100	$1.55	$155	143,163	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	S Sale	2020-05-11	2020-05-13	100	$50.00	$5.0K	143,063	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-05-08	2020-05-12	6,656	—	$0	40,155	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-05-08	2020-05-12	6,085	—	$0	23,557	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-05-08	2020-05-12	12,741	$49.53	$631.1K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-05-08	2020-05-12	6,085	$8.04	$48.9K	6,085	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-05-08	2020-05-12	6,656	$11.50	$76.5K	12,741	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise deriv	2020-05-06	2020-05-07	6,813	—	$0	17,712	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise deriv	2020-05-06	2020-05-07	3,900	—	$0	13,746	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise deriv	2020-05-06	2020-05-07	750	—	$0	7,125	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-05-06	2020-05-07	2,467	—	$0	22,425	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-05-06	2020-05-07	10,099	—	$0	99,142	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise deriv	2020-05-06	2020-05-07	2,836	—	$0	0	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise deriv	2020-05-06	2020-05-07	7,164	—	$0	33,330	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	S Sale	2020-05-06	2020-05-07	11,463	$45.06	$516.5K	143,063	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise	2020-05-06	2020-05-07	3,900	$7.60	$29.6K	154,526	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise	2020-05-06	2020-05-07	750	$11.50	$8.6K	150,626	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise	2020-05-06	2020-05-07	6,813	$1.55	$10.6K	149,876	SEC↗
Audia James E	Director	S Sale	2020-05-06	2020-05-07	7,500	$45.15	$338.6K	31,534	SEC↗
Valentine Karen	See Remarks	S Sale	2020-05-06	2020-05-07	12,566	$40.10	$503.9K	0	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-05-06	2020-05-07	10,099	$11.50	$116.1K	10,099	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-05-06	2020-05-07	2,467	$8.76	$21.6K	12,566	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise	2020-05-06	2020-05-07	2,836	$5.62	$15.9K	10,000	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise	2020-05-06	2020-05-07	7,164	$7.60	$54.4K	7,164	SEC↗
Trojer Patrick	Chief Scientific Officer	S Sale	2020-05-06	2020-05-07	10,000	$45.16	$451.6K	0	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise deriv	2020-05-05	2020-05-07	520	—	$0	17,646	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise deriv	2020-05-05	2020-05-07	2,325	—	$0	24,525	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise deriv	2020-05-05	2020-05-07	300	—	$0	7,875	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-05-05	2020-05-07	4,744	—	$0	109,241	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise	2020-05-05	2020-05-07	520	$7.60	$4.0K	146,208	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise	2020-05-05	2020-05-07	2,325	$1.55	$3.6K	145,388	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise	2020-05-05	2020-05-07	300	$11.50	$3.5K	145,688	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	S Sale	2020-05-05	2020-05-07	3,145	$40.01	$125.8K	143,063	SEC↗
Valentine Karen	See Remarks	S Sale	2020-05-05	2020-05-07	4,744	$40.01	$189.8K	0	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-05-05	2020-05-07	4,744	$11.50	$54.6K	4,744	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-04-27	2020-04-29	400	—	$0	113,985	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise deriv	2020-04-27	2020-04-29	400	—	$0	26,850	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-04-27	2020-04-29	400	$11.50	$4.6K	400	SEC↗
Valentine Karen	See Remarks	S Sale	2020-04-27	2020-04-29	400	$40.13	$16.1K	0	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	M Exercise	2020-04-27	2020-04-29	400	$1.55	$620	143,463	SEC↗
GOLDSMITH MARK A	Director, 10% Owner	S Sale	2020-04-27	2020-04-29	400	$40.12	$16.0K	143,063	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-04-20	2020-04-22	789	—	$0	114,385	SEC↗
Valentine Karen	See Remarks	S Sale	2020-04-20	2020-04-22	789	$33.65	$26.5K	0	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-04-20	2020-04-22	789	$11.50	$9.1K	789	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-04-17	2020-04-20	2,300	—	$0	115,174	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-04-17	2020-04-20	760	—	$0	87,033	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-04-17	2020-04-20	2,300	$11.50	$26.4K	2,300	SEC↗
Valentine Karen	See Remarks	S Sale	2020-04-17	2020-04-20	2,300	$35.19	$80.9K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-04-17	2020-04-20	760	$6.61	$5.0K	760	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-04-17	2020-04-20	760	$35.29	$26.8K	0	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-04-16	2020-04-20	2,998	—	$0	117,474	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-04-16	2020-04-20	2,998	$11.50	$34.5K	2,998	SEC↗
Valentine Karen	See Remarks	S Sale	2020-04-16	2020-04-20	1,955	$33.29	$65.1K	1,043	SEC↗
Valentine Karen	See Remarks	S Sale	2020-04-16	2020-04-20	1,043	$34.09	$35.6K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-04-14	2020-04-16	1,225	—	$0	84,164	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-04-14	2020-04-16	1,225	$35.20	$43.1K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-04-14	2020-04-16	1,225	$8.76	$10.7K	1,225	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-04-09	2020-04-13	111	—	$0	85,389	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-04-09	2020-04-13	589	—	$0	20,611	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-04-09	2020-04-13	635	—	$0	24,892	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-04-09	2020-04-13	111	$35.02	$3.9K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-04-09	2020-04-13	589	$7.60	$4.5K	589	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-04-09	2020-04-13	589	$35.02	$20.6K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-04-09	2020-04-13	111	$8.76	$972	111	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-04-09	2020-04-13	635	$8.76	$5.6K	635	SEC↗
Valentine Karen	See Remarks	S Sale	2020-04-09	2020-04-13	635	$35.02	$22.2K	0	SEC↗
Levy Richard S	Director	A Award deriv	2020-04-03	2020-04-06	26,342	—	$0	26,342	SEC↗
GOEDDEL DAVID V	10% Owner	P Buy	2020-03-20	2020-03-23	5,539	$23.15	$128.2K	6,051,376	SEC↗
COLUMN GROUP III GP, LP	10% Owner	P Buy	2020-03-20	2020-03-23	5,539	$23.15	$128.2K	6,051,376	SEC↗
GOEDDEL DAVID V	10% Owner	P Buy	2020-03-19	2020-03-23	36,135	$22.38	$808.7K	6,045,837	SEC↗
COLUMN GROUP III GP, LP	10% Owner	P Buy	2020-03-19	2020-03-23	36,135	$22.38	$808.7K	6,045,837	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-03-09	2020-03-11	617	—	$0	25,527	SEC↗
Valentine Karen	See Remarks	S Sale	2020-03-09	2020-03-11	152	$31.17	$4.7K	465	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-03-09	2020-03-11	617	$8.76	$5.4K	617	SEC↗
Valentine Karen	See Remarks	S Sale	2020-03-09	2020-03-11	335	$32.08	$10.7K	130	SEC↗
Valentine Karen	See Remarks	S Sale	2020-03-09	2020-03-11	130	$32.92	$4.3K	0	SEC↗
Valentine Karen	Chief Legal Officer	A Award deriv	2020-02-14	2020-02-18	41,800	—	$0	41,800	SEC↗
Senderowicz Adrian	Chief Medical Officer	A Award deriv	2020-02-14	2020-02-18	50,000	—	$0	50,000	SEC↗
Trojer Patrick	Chief Scientific Officer	A Award deriv	2020-02-14	2020-02-18	55,000	—	$0	55,000	SEC↗
Reeve Emma	Chief Financial Officer	A Award deriv	2020-02-14	2020-02-18	60,000	—	$0	60,000	SEC↗
Raythatha Jigar	President and CEO	A Award deriv	2020-02-14	2020-02-18	200,000	—	$0	200,000	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-02-13	2020-02-14	1,906	—	$0	26,144	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-02-13	2020-02-14	2,567	—	$0	120,472	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-02-13	2020-02-14	5,521	—	$0	29,642	SEC↗
Valentine Karen	See Remarks	S Sale	2020-02-13	2020-02-14	4,473	$35.07	$156.9K	0	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-02-13	2020-02-14	1,906	$8.76	$16.7K	1,906	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-02-13	2020-02-14	2,567	$11.50	$29.5K	4,473	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-02-13	2020-02-14	5,521	$8.04	$44.4K	5,521	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-02-13	2020-02-14	5,521	$35.06	$193.6K	0	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-02-12	2020-02-14	1,500	—	$0	123,039	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-02-12	2020-02-14	1,103	—	$0	35,163	SEC↗
Valentine Karen	See Remarks	S Sale	2020-02-12	2020-02-14	1,500	$35.02	$52.5K	0	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-02-12	2020-02-14	1,500	$11.50	$17.3K	1,500	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-02-12	2020-02-14	1,103	$35.02	$38.6K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-02-12	2020-02-14	1,103	$8.04	$8.9K	1,103	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-02-11	2020-02-12	8,550	—	$0	122,689	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-02-11	2020-02-12	7,212	—	$0	21,200	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-02-11	2020-02-12	1,430	—	$0	36,266	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-02-11	2020-02-13	8,550	—	$0	124,539	SEC↗
Valentine Karen	See Remarks	S Sale	2020-02-11	2020-02-12	8,550	$35.03	$299.5K	0	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-02-11	2020-02-12	8,550	$11.50	$98.3K	8,550	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-02-11	2020-02-12	1,430	$35.04	$50.1K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-02-11	2020-02-12	1,430	$8.04	$11.5K	1,430	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-02-11	2020-02-12	7,212	$35.04	$252.7K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-02-11	2020-02-12	7,212	$7.60	$54.8K	7,212	SEC↗
Valentine Karen	See Remarks	S Sale	2020-02-11	2020-02-13	8,550	$35.03	$299.5K	0	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-02-11	2020-02-13	8,550	$11.50	$98.3K	8,550	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-02-10	2020-02-12	14,096	—	$0	131,239	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2020-02-10	2020-02-12	200	—	$0	28,412	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-02-10	2020-02-13	1,850	—	$0	28,050	SEC↗
Valentine Karen	See Remarks	M Exercise deriv	2020-02-10	2020-02-13	12,246	—	$0	133,089	SEC↗
Valentine Karen	See Remarks	S Sale	2020-02-10	2020-02-12	14,096	$33.51	$472.4K	0	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-02-10	2020-02-12	14,096	$11.50	$162.1K	14,096	SEC↗
Reeve Emma	Chief Financial Officer	S Sale	2020-02-10	2020-02-12	200	$35.00	$7.0K	0	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise	2020-02-10	2020-02-12	200	$7.60	$1.5K	200	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-02-10	2020-02-13	1,850	$8.76	$16.2K	1,850	SEC↗
Valentine Karen	See Remarks	M Exercise	2020-02-10	2020-02-13	12,246	$11.50	$140.8K	14,096	SEC↗
Valentine Karen	See Remarks	S Sale	2020-02-10	2020-02-13	14,096	$33.51	$472.4K	0	SEC↗
Venrock Healthcare Capital Par	10% Owner	P Buy	2019-12-13	2019-12-16	400,000	$34.50	$13.80M	4,016,873	SEC↗
EVNIN ANTHONY B	Director	P Buy	2019-12-13	2019-12-16	400,000	$34.50	$13.80M	5,742,765	SEC↗
REGENTS OF THE UNIVERSITY OF C	10% Owner	S Sale	2019-11-12	2019-11-12	12,800	$32.77	$419.5K	2,111,290	SEC↗
REGENTS OF THE UNIVERSITY OF C	10% Owner	S Sale	2019-11-12	2019-11-13	12,800	$32.77	$419.5K	2,110,290	SEC↗
REGENTS OF THE UNIVERSITY OF C	10% Owner	S Sale	2019-11-08	2019-11-12	74,316	$30.44	$2.26M	2,127,090	SEC↗
REGENTS OF THE UNIVERSITY OF C	10% Owner	S Sale	2019-11-08	2019-11-12	1,000,000	$30.25	$30.25M	2,197,406	SEC↗
REGENTS OF THE UNIVERSITY OF C	10% Owner	S Sale	2019-11-08	2019-11-13	74,316	$30.44	$2.26M	2,123,090	SEC↗
REGENTS OF THE UNIVERSITY OF C	10% Owner	S Sale	2019-11-08	2019-11-13	100,000	$30.25	$3.02M	2,197,406	SEC↗
Raythatha Jigar	See Remarks	M Exercise deriv	2019-11-06	2019-11-08	102,750	—	$0	433,175	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise deriv	2019-11-06	2019-11-08	839	—	$0	850	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise deriv	2019-11-06	2019-11-08	2,893	—	$0	43,387	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise deriv	2019-11-06	2019-11-08	5,786	—	$0	40,494	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise deriv	2019-11-06	2019-11-08	18,765	—	$0	2,836	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise deriv	2019-11-06	2019-11-08	801	—	$0	3,121	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise deriv	2019-11-06	2019-11-08	195	—	$0	0	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise deriv	2019-11-06	2019-11-08	8,641	—	$0	17,312	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2019-11-06	2019-11-08	9,084	—	$0	28,612	SEC↗
Reeve Emma	Chief Financial Officer	M Exercise deriv	2019-11-06	2019-11-08	56,542	—	$0	87,793	SEC↗
Senderowicz Adrian	Chief Medical Officer	M Exercise deriv	2019-11-06	2019-11-08	27,232	—	$0	109,020	SEC↗
Raythatha Jigar	See Remarks	S Sale	2019-11-06	2019-11-08	3,170	$21.20	$67.2K	97,161	SEC↗
Raythatha Jigar	See Remarks	M Exercise	2019-11-06	2019-11-08	102,750	$5.51	$566.2K	117,711	SEC↗
Raythatha Jigar	See Remarks	S Sale	2019-11-06	2019-11-08	20,200	$35.23	$711.6K	15,311	SEC↗
Raythatha Jigar	See Remarks	S Sale	2019-11-06	2019-11-08	350	$36.01	$12.6K	14,961	SEC↗
Raythatha Jigar	See Remarks	S Sale	2019-11-06	2019-11-08	20,550	$25.06	$515.0K	76,611	SEC↗
Raythatha Jigar	See Remarks	S Sale	2019-11-06	2019-11-08	29,005	$30.19	$875.7K	47,606	SEC↗
Raythatha Jigar	See Remarks	S Sale	2019-11-06	2019-11-08	12,095	$31.32	$378.8K	35,511	SEC↗
Raythatha Jigar	See Remarks	S Sale	2019-11-06	2019-11-08	17,380	$20.18	$350.7K	100,331	SEC↗
Audia James E	Director	S Sale	2019-11-06	2019-11-08	4,500	$17.55	$79.0K	57,034	SEC↗
Audia James E	Director	S Sale	2019-11-06	2019-11-08	10,500	$18.58	$195.1K	46,534	SEC↗
Audia James E	Director	S Sale	2019-11-06	2019-11-08	7,500	$19.11	$143.3K	39,034	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise	2019-11-06	2019-11-08	195	$4.08	$796	8,417	SEC↗
Trojer Patrick	Chief Scientific Officer	S Sale	2019-11-06	2019-11-08	11,535	$30.16	$347.9K	0	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise	2019-11-06	2019-11-08	801	$5.51	$4.4K	9,218	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise	2019-11-06	2019-11-08	8,641	$5.51	$47.6K	17,859	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise	2019-11-06	2019-11-08	18,765	$5.62	$105.5K	36,624	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise	2019-11-06	2019-11-08	5,786	$7.60	$44.0K	42,410	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise	2019-11-06	2019-11-08	839	$7.60	$6.4K	43,249	SEC↗
Trojer Patrick	Chief Scientific Officer	M Exercise	2019-11-06	2019-11-08	2,893	$8.04	$23.3K	46,142	SEC↗
Trojer Patrick	Chief Scientific Officer	S Sale	2019-11-06	2019-11-08	11,535	$20.01	$230.8K	34,607	SEC↗