Open-mkt buys · 90d
$294.7K
6 trades · 2 insiders
Open-mkt sales · 90d
$400.2K
6 trades · 1 insiders
Net · 90d
$-105.5K
Insiders on file
25
Daily buy vs sell · 90 days
■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Errico Thomas J. | Director, 10% Owner | 40 | $844.6K | $0 | 2026-09-14 |
| Fox Michael | See Remarks | 7 | $98.0K | $0 | 2026-09-11 |
| Bonfiglioli Elena | Director | 3 | $0 | $0 | 2026-09-09 |
| Theofilos James Charles | Director | 3 | $0 | $0 | 2026-09-09 |
| Goldstein Julie Ann | Director | 11 | $1.3K | $0 | 2026-09-09 |
| Wilber Patricia | Director | 8 | $208 | $0 | 2026-09-09 |
| GANDOLFO JOHN P | Director | 12 | $29.4K | $0 | 2026-09-09 |
| Lev Joshua S. | See Remarks | 28 | $0 | $505.8K | 2026-09-08 |
| Goldberger Daniel S | Other | 36 | $597.9K | $640.8K | 2026-04-23 |
| PATTON THOMAS M | Director | 10 | $562 | $0 | 2025-09-02 |
| Theofilos Charles Steve | Director | 4 | $0 | $0 | 2024-09-03 |
| CUNEO F PETER | Director | 8 | $170 | $0 | 2024-09-03 |
| POSNER BRIAN M | Chief Financial Officer | 10 | $34.3K | $6.0K | 2024-01-12 |
| Moody Trevor J | Director | 10 | $221.7K | $0 | 2023-08-02 |
| Errico Joseph P | See Remarks | 21 | $276.5K | $535.3K | 2022-12-13 |
| Ondra Stephen | Director | 3 | $0 | $0 | 2021-06-11 |
| ATIEH MICHAEL G | Director | 3 | $0 | $0 | 2021-06-11 |
| TULLIS JAMES L L | Director | 6 | $1.59M | $0 | 2020-04-14 |
| Core Ventures II, LLC | 10% Owner | 3 | $0 | $0 | 2019-11-19 |
| Amato Francis R. | Chief Executive Officer | 4 | $49.0K | $0 | 2019-06-07 |
| Colucci Nicholas | Director | 1 | $0 | $0 | 2019-06-07 |
| COX CARRIE SMITH | Director | 5 | $118.7K | $0 | 2019-06-07 |
| Staats Peter S. | Chief Medical Officer | 3 | $48.3K | $0 | 2019-03-28 |
| Vraniak Glenn S. | Chief Financial Officer | 2 | $0 | $0 | 2019-03-22 |
| Merck Global Health Innovation Fund, LLC | 10% Owner | 1 | $2.50M | $0 | 2018-06-21 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Errico Thomas J. | Director | P Buy | 2026-09-14 | 2026-09-22 | 5,000 | $9.82 | $49.1K | 363,904 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2026-09-14 | 2026-09-22 | 5,000 | $9.82 | $49.1K | 363,904 | SEC↗ |
| Fox Michael | See Remarks | A Award | 2026-09-11 | 2026-09-14 | 5,000 | $9.80 | $49.0K | 130,000 | SEC↗ |
| Fox Michael | See Remarks | P Buy | 2026-09-11 | 2026-09-18 | 5,000 | $9.80 | $49.0K | 130,000 | SEC↗ |
| Fox Michael | See Remarks | A Award | 2026-09-11 | 2026-09-14 | 5,000 | $9.80 | $49.0K | 130,000 | SEC↗ |
| Fox Michael | See Remarks | P Buy | 2026-09-11 | 2026-09-18 | 5,000 | $9.80 | $49.0K | 130,000 | SEC↗ |
| GANDOLFO JOHN P | Director | A Award | 2026-09-09 | 2026-09-10 | 11,123 | — | $0 | 99,221 | SEC↗ |
| Errico Thomas J. | Director | A Award | 2026-09-09 | 2026-09-10 | 15,572 | — | $0 | 358,904 | SEC↗ |
| Goldstein Julie Ann | Director | A Award | 2026-09-09 | 2026-09-10 | 11,123 | — | $0 | 112,510 | SEC↗ |
| Bonfiglioli Elena | Director | A Award | 2026-09-09 | 2026-09-10 | 11,123 | — | $0 | 41,672 | SEC↗ |
| Wilber Patricia | Director | A Award | 2026-09-09 | 2026-09-10 | 11,123 | — | $0 | 83,448 | SEC↗ |
| Theofilos James Charles | Director | A Award | 2026-09-09 | 2026-09-10 | 11,123 | — | $0 | 34,670 | SEC↗ |
| Wilber Patricia | Director | A Award | 2026-09-09 | 2026-09-10 | 11,123 | — | $0 | 83,448 | SEC↗ |
| Theofilos James Charles | Director | A Award | 2026-09-09 | 2026-09-10 | 11,123 | — | $0 | 34,670 | SEC↗ |
| Goldstein Julie Ann | Director | A Award | 2026-09-09 | 2026-09-10 | 11,123 | — | $0 | 112,510 | SEC↗ |
| GANDOLFO JOHN P | Director | A Award | 2026-09-09 | 2026-09-10 | 11,123 | — | $0 | 99,221 | SEC↗ |
| Errico Thomas J. | Director | A Award | 2026-09-09 | 2026-09-10 | 15,572 | — | $0 | 358,904 | SEC↗ |
| Bonfiglioli Elena | Director | A Award | 2026-09-09 | 2026-09-10 | 11,123 | — | $0 | 41,672 | SEC↗ |
| Lev Joshua S. | See Remarks | A Award | 2026-09-08 | 2026-09-10 | 55,000 | — | $0 | 139,889 | SEC↗ |
| Fox Michael | See Remarks | A Award | 2026-09-08 | 2026-09-10 | 55,000 | — | $0 | 125,000 | SEC↗ |
| Lev Joshua S. | See Remarks | A Award | 2026-09-08 | 2026-09-10 | 55,000 | — | $0 | 139,889 | SEC↗ |
| Fox Michael | See Remarks | A Award | 2026-09-08 | 2026-09-10 | 55,000 | — | $0 | 125,000 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | M Exercise deriv | 2026-08-25 | 2026-08-25 | 3,000 | — | $0 | 0 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | S Sale | 2026-08-25 | 2026-08-25 | 3,000 | $9.36 | $28.1K | 84,889 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | M Exercise | 2026-08-25 | 2026-08-25 | 3,000 | $4.50 | $13.5K | 87,889 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | M Exercise deriv | 2026-08-25 | 2026-08-25 | 3,000 | — | $0 | 0 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | S Sale | 2026-08-25 | 2026-08-25 | 3,000 | $9.36 | $28.1K | 84,889 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | M Exercise | 2026-08-25 | 2026-08-25 | 3,000 | $4.50 | $13.5K | 87,889 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | M Exercise deriv | 2026-08-24 | 2026-08-25 | 5,000 | — | $0 | 3,000 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | S Sale | 2026-08-24 | 2026-08-25 | 5,000 | $9.88 | $49.4K | 84,889 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | M Exercise | 2026-08-24 | 2026-08-25 | 5,000 | $4.50 | $22.5K | 89,889 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | M Exercise deriv | 2026-08-24 | 2026-08-25 | 5,000 | — | $0 | 3,000 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | S Sale | 2026-08-24 | 2026-08-25 | 5,000 | $9.88 | $49.4K | 84,889 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | M Exercise | 2026-08-24 | 2026-08-25 | 5,000 | $4.50 | $22.5K | 89,889 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | M Exercise deriv | 2026-08-21 | 2026-08-25 | 12,000 | — | $0 | 8,000 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | M Exercise | 2026-08-21 | 2026-08-25 | 12,000 | $4.50 | $54.0K | 96,889 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | S Sale | 2026-08-21 | 2026-08-25 | 12,000 | $10.22 | $122.6K | 84,889 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | M Exercise deriv | 2026-08-21 | 2026-08-25 | 12,000 | — | $0 | 8,000 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | S Sale | 2026-08-21 | 2026-08-25 | 12,000 | $10.22 | $122.6K | 84,889 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | M Exercise | 2026-08-21 | 2026-08-25 | 12,000 | $4.50 | $54.0K | 96,889 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2026-08-13 | 2026-08-17 | 5,000 | $9.85 | $49.3K | 343,332 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2026-08-13 | 2026-08-17 | 5,000 | $9.85 | $49.3K | 343,332 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | S Sale | 2026-05-28 | 2026-05-29 | 6,667 | $9.00 | $60.0K | 84,889 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | S Sale | 2026-05-22 | 2026-05-22 | 3,000 | $6.50 | $19.5K | 91,556 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2026-05-21 | 2026-05-26 | 9,992 | $5.99 | $59.9K | 360,071 | SEC↗ |
| Errico Thomas J. | Director | L Small acq | 2026-05-20 | 2026-05-26 | 8 | $5.98 | $48 | 350,079 | SEC↗ |
| Goldberger Daniel S | Other | S Sale | 2026-04-23 | 2026-06-12 | 80,000 | $6.80 | $544.0K | 211,471 | SEC↗ |
| Fox Michael | Chief Operating Officer | A Award | 2026-04-13 | 2026-04-14 | 70,000 | — | $0 | 70,000 | SEC↗ |
| Goldberger Daniel S | Other | S Sale | 2026-04-10 | 2026-04-14 | 16,072 | $6.02 | $96.8K | 291,471 | SEC↗ |
| Lev Joshua S. | CFO and Interim President | A Award | 2026-04-01 | 2026-04-01 | 45,000 | — | $0 | 94,556 | SEC↗ |
| Errico Thomas J. | Director | X Exercise deriv | 2026-03-19 | 2026-03-20 | 22,803 | — | $0 | 0 | SEC↗ |
| Errico Thomas J. | Director | X Exercise deriv | 2026-03-19 | 2026-03-20 | 19,252 | — | $0 | 0 | SEC↗ |
| Errico Thomas J. | Director | X Exercise | 2026-03-19 | 2026-03-20 | 19,252 | $6.43 | $123.8K | 350,071 | SEC↗ |
| Errico Thomas J. | Director | X Exercise | 2026-03-19 | 2026-03-20 | 22,803 | $4.35 | $99.2K | 330,819 | SEC↗ |
| Lev Joshua S. | Chief Financial Officer | A Award | 2026-01-26 | 2026-01-28 | 25,000 | — | $0 | 49,556 | SEC↗ |
| Lev Joshua S. | Chief Financial Officer | A Award | 2026-01-26 | 2026-01-28 | 2,889 | — | $0 | 24,556 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | A Award | 2026-01-26 | 2026-01-28 | 20,375 | $7.47 | $152.2K | 312,940 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | A Award | 2026-01-26 | 2026-01-28 | 26,000 | — | $0 | 338,940 | SEC↗ |
| Lev Joshua S. | Chief Financial Officer | S Sale | 2025-12-04 | 2025-12-05 | 2,500 | $5.05 | $12.6K | 21,667 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2025-12-02 | 2025-12-03 | 1,000 | $4.84 | $4.8K | 292,565 | SEC↗ |
| Lev Joshua S. | Chief Financial Officer | S Sale | 2025-11-12 | 2025-11-14 | 2,166 | $6.18 | $13.4K | 23,667 | SEC↗ |
| Bonfiglioli Elena | Director | A Award | 2025-09-10 | 2025-09-12 | 30,549 | — | $0 | 30,549 | SEC↗ |
| PATTON THOMAS M | Director | A Award | 2025-09-02 | 2025-09-04 | 19,011 | — | $0 | 102,782 | SEC↗ |
| GANDOLFO JOHN P | Director | A Award | 2025-09-02 | 2025-09-04 | 19,011 | — | $0 | 88,098 | SEC↗ |
| Errico Thomas J. | Director | A Award | 2025-09-02 | 2025-09-04 | 26,615 | — | $0 | 308,016 | SEC↗ |
| Goldstein Julie Ann | Director | A Award | 2025-09-02 | 2025-09-04 | 19,011 | — | $0 | 101,387 | SEC↗ |
| Wilber Patricia | Director | A Award | 2025-09-02 | 2025-09-04 | 19,011 | — | $0 | 72,325 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2025-08-11 | 2025-08-12 | 1,000 | $4.23 | $4.2K | 291,565 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2025-08-11 | 2025-08-13 | 15,000 | $4.47 | $67.0K | 281,401 | SEC↗ |
| Theofilos James Charles | Director | A Award | 2025-08-01 | 2025-08-05 | 22,156 | — | $0 | 23,547 | SEC↗ |
| GANDOLFO JOHN P | Director | P Buy | 2025-05-23 | 2025-05-27 | 1,800 | $5.01 | $9.0K | 69,087 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2025-05-12 | 2025-05-13 | 10,000 | $4.77 | $47.7K | 266,401 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2025-03-17 | 2025-03-17 | 6,000 | $8.10 | $48.6K | 256,401 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2025-03-17 | 2025-03-18 | 1,000 | $8.59 | $8.6K | 290,565 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | A Award | 2025-01-18 | 2025-01-21 | 40,000 | — | $0 | 289,565 | SEC↗ |
| Lev Joshua S. | Chief Financial Officer | A Award | 2025-01-15 | 2025-01-17 | 10,000 | — | $0 | 26,333 | SEC↗ |
| CUNEO F PETER | Director | A Award deriv | 2024-09-03 | 2024-09-05 | 27,783 | — | $0 | 27,783 | SEC↗ |
| Goldstein Julie Ann | Director | A Award deriv | 2024-09-03 | 2024-09-05 | 19,845 | — | $0 | 19,845 | SEC↗ |
| Theofilos Charles Steve | Director | A Award | 2024-09-03 | 2024-09-05 | 16,582 | — | $0 | 454,202 | SEC↗ |
| PATTON THOMAS M | Director | A Award | 2024-09-03 | 2024-09-05 | 16,583 | — | $0 | 83,771 | SEC↗ |
| GANDOLFO JOHN P | Director | A Award | 2024-09-03 | 2024-09-05 | 16,583 | — | $0 | 67,287 | SEC↗ |
| Wilber Patricia | Director | A Award | 2024-09-03 | 2024-09-05 | 16,583 | — | $0 | 49,697 | SEC↗ |
| Errico Thomas J. | Director | A Award | 2024-09-03 | 2024-09-05 | 16,583 | — | $0 | 250,401 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2024-08-15 | 2024-08-19 | 5,000 | $6.12 | $30.6K | 233,818 | SEC↗ |
| CUNEO F PETER | Director | A Award deriv | 2024-07-11 | 2024-07-15 | 50,000 | — | $0 | 50,000 | SEC↗ |
| GANDOLFO JOHN P | Director | P Buy | 2024-06-13 | 2024-06-17 | 1,000 | $6.43 | $6.4K | 50,704 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy deriv | 2024-06-05 | 2024-06-06 | 19,252 | $0.06 | $1.2K | 19,252 | SEC↗ |
| PATTON THOMAS M | Director | P Buy deriv | 2024-06-05 | 2024-06-06 | 3,850 | $0.06 | $231 | 3,850 | SEC↗ |
| Goldstein Julie Ann | Director | P Buy deriv | 2024-06-05 | 2024-06-06 | 3,850 | $0.06 | $231 | 3,850 | SEC↗ |
| Wilber Patricia | Director | P Buy deriv | 2024-06-05 | 2024-06-06 | 3,465 | $0.06 | $208 | 3,465 | SEC↗ |
| Errico Thomas J. | Director | P Buy deriv | 2024-06-05 | 2024-06-07 | 19,252 | $0.06 | $1.2K | 19,252 | SEC↗ |
| Theofilos Charles Steve | Director | P Buy deriv | 2024-06-05 | 2024-06-07 | 770,119 | — | $0 | 770,119 | SEC↗ |
| Theofilos Charles Steve | Director | P Buy deriv | 2024-06-05 | 2024-06-07 | 385,059 | — | $0 | 385,059 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2024-06-05 | 2024-06-06 | 38,505 | $6.43 | $247.6K | 249,565 | SEC↗ |
| PATTON THOMAS M | Director | A Award | 2024-06-05 | 2024-06-06 | 7,701 | $6.43 | $49.5K | 67,188 | SEC↗ |
| Goldstein Julie Ann | Director | A Award | 2024-06-05 | 2024-06-06 | 7,701 | $6.43 | $49.5K | 77,380 | SEC↗ |
| Wilber Patricia | Director | A Award | 2024-06-05 | 2024-06-06 | 6,931 | $6.43 | $44.6K | 33,114 | SEC↗ |
| Errico Thomas J. | Director | A Award | 2024-06-05 | 2024-06-07 | 38,505 | $6.43 | $247.6K | 228,818 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | A Award | 2024-01-16 | 2024-01-18 | 75,000 | — | $0 | 211,060 | SEC↗ |
| POSNER BRIAN M | Chief Financial Officer | P Buy | 2024-01-12 | 2024-01-17 | 16,000 | — | $0 | 22,437 | SEC↗ |
| Theofilos Charles Steve | Director | A Award | 2024-01-01 | 2024-01-03 | 25,210 | — | $0 | 437,620 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2023-09-15 | 2023-09-19 | 1,500 | $5.56 | $8.3K | 136,060 | SEC↗ |
| Goldstein Julie Ann | Director | A Award deriv | 2023-08-04 | 2023-08-08 | 25,989 | — | $0 | 25,989 | SEC↗ |
| CUNEO F PETER | Director | A Award deriv | 2023-08-04 | 2023-08-08 | 36,383 | — | $0 | 36,383 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2023-08-04 | 2023-08-08 | 50,000 | — | $0 | 134,560 | SEC↗ |
| GANDOLFO JOHN P | Director | A Award | 2023-08-04 | 2023-08-08 | 21,739 | — | $0 | 49,704 | SEC↗ |
| PATTON THOMAS M | Director | A Award | 2023-08-04 | 2023-08-08 | 21,739 | — | $0 | 59,487 | SEC↗ |
| Errico Thomas J. | Director | A Award | 2023-08-04 | 2023-08-08 | 21,739 | — | $0 | 189,606 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy deriv | 2023-08-02 | 2023-08-03 | 25,495 | $0.06 | $1.5K | 25,495 | SEC↗ |
| Errico Thomas J. | Director | P Buy deriv | 2023-08-02 | 2023-08-04 | 22,803 | $0.06 | $1.4K | 22,803 | SEC↗ |
| PATTON THOMAS M | Director | P Buy deriv | 2023-08-02 | 2023-08-04 | 5,524 | $0.06 | $331 | 5,524 | SEC↗ |
| CUNEO F PETER | Director | P Buy deriv | 2023-08-02 | 2023-08-04 | 2,832 | $0.06 | $170 | 2,832 | SEC↗ |
| Goldstein Julie Ann | Director | P Buy deriv | 2023-08-02 | 2023-08-04 | 16,997 | $0.06 | $1.0K | 16,997 | SEC↗ |
| Moody Trevor J | Director | P Buy deriv | 2023-08-02 | 2023-08-04 | 11,331 | $0.06 | $680 | 11,331 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2023-08-02 | 2023-08-03 | 50,991 | $4.35 | $221.8K | 84,560 | SEC↗ |
| Errico Thomas J. | Director | A Award | 2023-08-02 | 2023-08-04 | 45,607 | $4.35 | $198.4K | 167,867 | SEC↗ |
| PATTON THOMAS M | Director | A Award | 2023-08-02 | 2023-08-04 | 11,049 | $4.35 | $48.1K | 37,748 | SEC↗ |
| CUNEO F PETER | Director | A Award | 2023-08-02 | 2023-08-04 | 5,665 | $4.35 | $24.6K | 5,665 | SEC↗ |
| Goldstein Julie Ann | Director | A Award | 2023-08-02 | 2023-08-04 | 33,994 | $4.35 | $147.9K | 69,679 | SEC↗ |
| Moody Trevor J | Director | A Award | 2023-08-02 | 2023-08-04 | 22,662 | $4.35 | $98.6K | 67,592 | SEC↗ |
| Wilber Patricia | Director | A Award | 2023-08-02 | 2023-08-08 | 21,739 | — | $0 | 26,183 | SEC↗ |
| POSNER BRIAN M | Chief Financial Officer | A Award deriv | 2023-07-31 | 2023-08-02 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2023-03-17 | 2023-03-20 | 500 | $3.43 | $1.7K | 33,569 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2023-03-16 | 2023-03-20 | 500 | $3.46 | $1.7K | 33,069 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2023-03-15 | 2023-03-16 | 500 | $3.55 | $1.8K | 467,542 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2023-03-14 | 2023-03-16 | 500 | $3.73 | $1.9K | 467,042 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2023-03-13 | 2023-03-16 | 500 | $3.86 | $1.9K | 466,542 | SEC↗ |
| Errico Thomas J. | Director | A Award | 2023-03-13 | 2023-03-20 | 6,750 | $3.61 | $24.4K | 122,260 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2022-12-14 | 2022-12-16 | 5,000 | $0.35 | $1.8K | 466,042 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2022-12-13 | 2022-12-15 | 5,000 | $0.33 | $1.6K | 461,042 | SEC↗ |
| Errico Joseph P | Director | P Buy | 2022-12-13 | 2022-12-15 | 100,000 | $0.33 | $33.0K | 2,724,841 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2022-12-12 | 2022-12-14 | 5,000 | $0.32 | $1.6K | 456,042 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2022-12-09 | 2022-12-13 | 5,000 | $0.30 | $1.5K | 451,042 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2022-12-08 | 2022-12-12 | 10,000 | $0.28 | $2.8K | 446,042 | SEC↗ |
| CUNEO F PETER | Director | A Award deriv | 2022-12-02 | 2022-12-06 | 322,534 | — | $0 | 322,534 | SEC↗ |
| Moody Trevor J | Director | A Award | 2022-12-02 | 2022-12-06 | 205,987 | — | $0 | 673,952 | SEC↗ |
| GANDOLFO JOHN P | Director | A Award | 2022-12-02 | 2022-12-06 | 205,987 | — | $0 | 419,497 | SEC↗ |
| PATTON THOMAS M | Director | A Award | 2022-12-02 | 2022-12-06 | 205,987 | — | $0 | 400,497 | SEC↗ |
| Errico Joseph P | Director | A Award | 2022-12-02 | 2022-12-06 | 205,987 | — | $0 | 2,624,841 | SEC↗ |
| Errico Thomas J. | Director | A Award | 2022-12-02 | 2022-12-06 | 205,987 | — | $0 | 1,732,687 | SEC↗ |
| Errico Joseph P | Director | P Buy | 2022-11-29 | 2022-12-01 | 25,000 | $0.33 | $8.3K | 2,418,854 | SEC↗ |
| Errico Joseph P | Director | P Buy | 2022-11-25 | 2022-11-29 | 50,000 | $0.31 | $15.5K | 2,393,854 | SEC↗ |
| Errico Joseph P | Director | P Buy | 2022-11-23 | 2022-11-28 | 100,000 | $0.31 | $31.0K | 2,343,854 | SEC↗ |
| Errico Joseph P | Director | P Buy | 2022-11-22 | 2022-11-25 | 75,000 | $0.33 | $24.8K | 2,243,854 | SEC↗ |
| Errico Joseph P | Director | P Buy | 2022-11-17 | 2022-11-21 | 100,000 | $0.31 | $31.0K | 2,168,854 | SEC↗ |
| Errico Joseph P | Director | P Buy | 2022-11-16 | 2022-11-18 | 100,000 | $0.29 | $29.0K | 2,068,854 | SEC↗ |
| Errico Joseph P | Director | P Buy | 2022-11-14 | 2022-11-16 | 100,000 | $0.24 | $24.0K | 1,968,854 | SEC↗ |
| Errico Joseph P | Director | P Buy | 2022-11-10 | 2022-11-15 | 100,000 | $0.24 | $24.0K | 1,868,854 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2022-11-08 | 2022-11-10 | 100,000 | $0.22 | $22.0K | 1,526,700 | SEC↗ |
| Errico Joseph P | Director | P Buy | 2022-06-13 | 2022-06-15 | 100,000 | $0.56 | $56.0K | 1,765,651 | SEC↗ |
| Moody Trevor J | Director | P Buy | 2022-05-31 | 2022-06-01 | 39,478 | $0.44 | $17.4K | 423,455 | SEC↗ |
| Moody Trevor J | Director | P Buy | 2022-05-27 | 2022-06-01 | 10,522 | $0.43 | $4.5K | 383,977 | SEC↗ |
| Goldstein Julie Ann | Director | A Award | 2022-05-23 | 2022-05-25 | 100,000 | $0.40 | $40.0K | 460,212 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2022-05-19 | 2022-05-23 | 15,197 | $0.40 | $6.1K | 1,426,700 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2022-05-18 | 2022-05-19 | 42,032 | $0.40 | $16.8K | 1,411,503 | SEC↗ |
| GANDOLFO JOHN P | Director | P Buy | 2022-05-17 | 2022-05-18 | 15,000 | $0.36 | $5.4K | 19,000 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2022-05-17 | 2022-05-19 | 42,771 | $0.39 | $16.7K | 1,369,471 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2022-05-16 | 2022-05-17 | 28,208 | $0.34 | $9.6K | 328,516 | SEC↗ |
| Wilber Patricia | Director | A Award | 2022-03-15 | 2022-03-16 | 150,000 | — | $0 | 150,000 | SEC↗ |
| Goldstein Julie Ann | Director | A Award | 2022-03-15 | 2022-03-16 | 150,000 | — | $0 | 510,212 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | A Award deriv | 2022-01-17 | 2022-01-19 | 250,000 | — | $0 | 250,000 | SEC↗ |
| POSNER BRIAN M | Chief Financial Officer | A Award deriv | 2022-01-14 | 2022-01-18 | 100,000 | — | $0 | 100,000 | SEC↗ |
| POSNER BRIAN M | Chief Financial Officer | P Buy | 2021-12-10 | 2021-12-13 | 10,000 | $0.75 | $7.5K | 96,555 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2021-12-07 | 2021-12-08 | 15,000 | $0.71 | $10.7K | 300,308 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2021-11-23 | 2021-11-26 | 15,000 | $0.75 | $11.3K | 285,308 | SEC↗ |
| POSNER BRIAN M | Chief Financial Officer | P Buy | 2021-11-09 | 2021-11-10 | 10,000 | $0.96 | $9.6K | 86,555 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | M Exercise deriv | 2021-10-01 | 2021-10-05 | 53,764 | — | $0 | 107,528 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | M Exercise | 2021-10-01 | 2021-10-05 | 53,764 | — | $0 | 270,308 | SEC↗ |
| POSNER BRIAN M | Chief Financial Officer | S Sale | 2021-08-17 | 2021-08-19 | 6,478 | $0.92 | $6.0K | 76,555 | SEC↗ |
| Moody Trevor J | Director | P Buy | 2021-07-02 | 2021-07-07 | 100,000 | $1.00 | $100.0K | 373,455 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2021-07-02 | 2021-07-07 | 50,000 | $1.00 | $50.0K | 1,326,700 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | P Buy | 2021-07-02 | 2021-07-07 | 50,000 | $1.00 | $50.0K | 216,544 | SEC↗ |
| Errico Joseph P | Director | A Award deriv | 2021-06-11 | 2021-06-15 | 44,510 | — | $0 | 44,510 | SEC↗ |
| GANDOLFO JOHN P | Director | A Award deriv | 2021-06-11 | 2021-06-15 | 44,510 | — | $0 | 44,510 | SEC↗ |
| Moody Trevor J | Director | A Award deriv | 2021-06-11 | 2021-06-15 | 44,510 | — | $0 | 44,510 | SEC↗ |
| Errico Thomas J. | Director, 10% Owner | A Award deriv | 2021-06-11 | 2021-06-15 | 67,568 | — | $0 | 67,568 | SEC↗ |
| ATIEH MICHAEL G | Director | A Award deriv | 2021-06-11 | 2021-06-15 | 66,766 | — | $0 | 66,766 | SEC↗ |
| Ondra Stephen | Director | A Award deriv | 2021-06-11 | 2021-06-15 | 44,510 | — | $0 | 44,510 | SEC↗ |
| CUNEO F PETER | Director | A Award deriv | 2021-06-11 | 2021-06-15 | 67,568 | — | $0 | 67,568 | SEC↗ |
| PATTON THOMAS M | Director | A Award deriv | 2021-06-11 | 2021-06-15 | 44,510 | — | $0 | 44,510 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2021-05-17 | 2021-05-19 | 31,250 | $1.59 | $49.7K | 1,275,700 | SEC↗ |
| GANDOLFO JOHN P | Director | P Buy | 2021-03-16 | 2021-03-17 | 4,000 | $2.15 | $8.6K | 4,000 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | A Award deriv | 2021-01-25 | 2021-01-27 | 270,000 | — | $0 | 270,000 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | A Award | 2021-01-25 | 2021-01-26 | 112,781 | — | $0 | 166,544 | SEC↗ |
| POSNER BRIAN M | Chief Financial Officer | A Award deriv | 2021-01-18 | 2021-01-20 | 250,000 | — | $0 | 250,000 | SEC↗ |
| ATIEH MICHAEL G | Director | A Award deriv | 2020-06-12 | 2020-06-16 | 112,500 | — | $0 | 112,500 | SEC↗ |
| Errico Joseph P | Director, 10% Owner | A Award deriv | 2020-06-12 | 2020-06-16 | 75,000 | — | $0 | 75,000 | SEC↗ |
| Errico Thomas J. | Director, 10% Owner | A Award deriv | 2020-06-12 | 2020-06-16 | 75,000 | — | $0 | 75,000 | SEC↗ |
| Ondra Stephen | Director | A Award deriv | 2020-06-12 | 2020-06-16 | 75,000 | — | $0 | 75,000 | SEC↗ |
| POSNER BRIAN M | Chief Financial Officer | A Award deriv | 2020-06-12 | 2020-06-16 | 105,000 | — | $0 | 105,000 | SEC↗ |
| Moody Trevor J | Director | A Award deriv | 2020-06-12 | 2020-06-16 | 75,000 | — | $0 | 75,000 | SEC↗ |
| TULLIS JAMES L L | Director | P Buy | 2020-04-14 | 2020-04-16 | 1,764,705 | $0.85 | $1.50M | 1,764,705 | SEC↗ |
| Moody Trevor J | Director | P Buy | 2020-04-14 | 2020-04-16 | 116,647 | $0.85 | $99.1K | 177,944 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2020-04-14 | 2020-04-16 | 176,470 | $0.85 | $150.0K | 1,245,450 | SEC↗ |
| GANDOLFO JOHN P | Director | A Award deriv | 2020-04-02 | 2020-04-06 | 150,000 | — | $0 | 150,000 | SEC↗ |
| CUNEO F PETER | Director | A Award deriv | 2020-04-02 | 2020-04-06 | 150,000 | — | $0 | 150,000 | SEC↗ |
| PATTON THOMAS M | Director | A Award | 2020-04-02 | 2020-04-06 | 150,000 | — | $0 | 150,000 | SEC↗ |
| TULLIS JAMES L L | Director | J Other | 2019-12-12 | 2019-12-16 | 98,918 | — | $0 | 0 | SEC↗ |
| TULLIS JAMES L L | Director | J Other | 2019-12-12 | 2019-12-16 | 8,680 | — | $0 | 172,504 | SEC↗ |
| TULLIS JAMES L L | Director | P Buy | 2019-11-22 | 2019-11-26 | 4,984 | $1.43 | $7.1K | 163,824 | SEC↗ |
| Core Ventures II, LLC | 10% Owner | J Other | 2019-11-19 | 2019-11-20 | 1,156,494 | — | $0 | 646,342 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | A Award deriv | 2019-10-01 | 2019-10-03 | 215,053 | — | $0 | 215,053 | SEC↗ |
| Goldberger Daniel S | Chief Executive Officer | A Award deriv | 2019-10-01 | 2019-10-03 | 764,331 | — | $0 | 764,331 | SEC↗ |
| Errico Thomas J. | Director | A Award | 2019-08-19 | 2023-08-08 | 707 | $26.43 | $18.7K | 168,574 | SEC↗ |
| Errico Thomas J. | Director | P Buy | 2019-08-16 | 2019-08-20 | 18,974 | $1.62 | $30.7K | 883,237 | SEC↗ |
| TULLIS JAMES L L | Director | P Buy | 2019-08-16 | 2019-08-20 | 47,613 | $1.64 | $78.1K | 158,840 | SEC↗ |
| POSNER BRIAN M | Chief Financial Officer | A Award deriv | 2019-06-27 | 2019-07-01 | 73,033 | — | $0 | 73,033 | SEC↗ |
| Core Ventures II, LLC | 10% Owner | J Other | 2019-06-24 | 2019-06-26 | 4,697,813 | — | $0 | 1,802,836 | SEC↗ |
| Colucci Nicholas | Director | A Award deriv | 2019-06-07 | 2019-06-11 | 44,642 | — | $0 | 44,642 | SEC↗ |
| Ondra Stephen | Director | A Award deriv | 2019-06-07 | 2019-06-11 | 63,291 | — | $0 | 63,291 | SEC↗ |
| COX CARRIE SMITH | Director | A Award deriv | 2019-06-07 | 2019-06-11 | 66,964 | — | $0 | 66,964 | SEC↗ |
| TULLIS JAMES L L | Director | A Award deriv | 2019-06-07 | 2019-06-11 | 44,642 | — | $0 | 44,642 | SEC↗ |
| Errico Thomas J. | Director, 10% Owner | A Award deriv | 2019-06-07 | 2019-06-11 | 63,291 | — | $0 | 63,291 | SEC↗ |
| ATIEH MICHAEL G | Director | A Award deriv | 2019-06-07 | 2019-06-11 | 63,291 | — | $0 | 63,291 | SEC↗ |
| Amato Francis R. | Chief Executive Officer | A Award deriv | 2019-06-07 | 2019-06-11 | 22,321 | — | $0 | 22,321 | SEC↗ |
| Moody Trevor J | Director | A Award deriv | 2019-06-07 | 2019-06-11 | 44,642 | — | $0 | 44,642 | SEC↗ |
| Errico Thomas J. | Director, 10% Owner | P Buy | 2019-06-07 | 2019-06-11 | 7,000 | $1.77 | $12.4K | 484,651 | SEC↗ |
| Errico Thomas J. | Director, 10% Owner | P Buy | 2019-06-06 | 2019-06-06 | 15,000 | $1.82 | $27.3K | 471,651 | SEC↗ |
| Errico Thomas J. | Director, 10% Owner | P Buy | 2019-06-06 | 2019-06-06 | 6,000 | $1.64 | $9.8K | 477,651 | SEC↗ |
| POSNER BRIAN M | Chief Financial Officer | P Buy | 2019-06-06 | 2019-06-06 | 10,000 | $1.72 | $17.2K | 10,000 | SEC↗ |
| COX CARRIE SMITH | Director | P Buy | 2019-06-06 | 2019-06-06 | 10,000 | $1.82 | $18.2K | 21,000 | SEC↗ |
| Errico Joseph P | See Remarks | S Sale | 2019-04-12 | 2019-04-12 | 25,869 | $5.53 | $143.1K | 532,349 | SEC↗ |
| Errico Joseph P | See Remarks | S Sale | 2019-04-11 | 2019-04-12 | 13,723 | $5.49 | $75.3K | 558,218 | SEC↗ |
| Amato Francis R. | Chief Executive Officer | A Award deriv | 2019-04-01 | 2019-04-03 | 307,125 | — | $0 | 307,125 | SEC↗ |
| Amato Francis R. | Chief Executive Officer | A Award deriv | 2019-04-01 | 2019-04-03 | 74,404 | — | $0 | 74,404 | SEC↗ |
| Errico Joseph P | See Remarks | A Award deriv | 2019-04-01 | 2019-04-03 | 25,706 | — | $0 | 25,706 | SEC↗ |
| Errico Joseph P | See Remarks | A Award deriv | 2019-04-01 | 2019-04-03 | 106,112 | — | $0 | 106,112 | SEC↗ |
| Errico Joseph P | See Remarks | S Sale | 2019-04-01 | 2019-04-03 | 10,408 | $6.97 | $72.5K | 571,941 | SEC↗ |
| Staats Peter S. | Chief Medical Officer | A Award deriv | 2019-03-28 | 2019-04-01 | 47,000 | — | $0 | 47,000 | SEC↗ |
| Staats Peter S. | Chief Medical Officer | A Award | 2019-03-28 | 2019-04-01 | 8,976 | — | $0 | 163,612 | SEC↗ |
| Vraniak Glenn S. | Chief Financial Officer | A Award deriv | 2019-03-22 | 2019-03-26 | 18,750 | — | $0 | 155,685 | SEC↗ |
| Vraniak Glenn S. | Chief Financial Officer | A Award | 2019-03-22 | 2019-03-26 | 2,976 | $8.40 | $25.0K | 120,811 | SEC↗ |
| Errico Joseph P | See Remarks | S Sale | 2019-01-17 | 2019-01-17 | 7,841 | $4.84 | $38.0K | 582,349 | SEC↗ |
| Errico Joseph P | See Remarks | S Sale | 2019-01-16 | 2019-01-17 | 19,810 | $4.89 | $96.9K | 590,190 | SEC↗ |
| Errico Joseph P | See Remarks | S Sale | 2019-01-15 | 2019-01-17 | 22,349 | $4.90 | $109.5K | 610,000 | SEC↗ |
| Core Ventures II, LLC | 10% Owner | J Other | 2019-01-11 | 2019-01-15 | 1,232,056 | — | $0 | 6,500,649 | SEC↗ |
| Staats Peter S. | Chief Medical Officer | P Buy | 2018-12-13 | 2018-12-17 | 10,000 | $4.83 | $48.3K | 154,636 | SEC↗ |
| Amato Francis R. | Chief Executive Officer | P Buy | 2018-12-06 | 2018-12-10 | 7,500 | $6.53 | $49.0K | 358,831 | SEC↗ |
| COX CARRIE SMITH | Director | P Buy | 2018-12-03 | 2018-12-04 | 6,400 | $6.79 | $43.5K | 10,100 | SEC↗ |
| COX CARRIE SMITH | Director | P Buy | 2018-12-03 | 2018-12-04 | 900 | $6.78 | $6.1K | 11,000 | SEC↗ |
| COX CARRIE SMITH | Director | P Buy | 2018-08-17 | 2018-08-20 | 3,700 | $13.76 | $50.9K | 17,033 | SEC↗ |
| Merck Global Health Innovation | 10% Owner | P Buy | 2018-06-21 | 2018-06-22 | 166,666 | $15.00 | $2.50M | 3,346,032 | SEC↗ |