EVOK

Evoke Pharma IncCIK 1403708 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for EVOK PRO

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AI insights for EVOK

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Kowieski Mark	Chief Financial Officer	6	$0	$0	2025-12-17
PYSZCZYMUKA GREG	Director	4	$0	$0	2025-12-17
Mack Daniel	10% Owner	7	$0	$180	2025-12-17
Smeal Benjamin C.	Director	4	$0	$0	2025-12-17
CARLSON MARILYN R.	Chief Medical Officer	39	$0	$0	2025-12-17
Brady Todd C	Director	19	$22.8K	$0	2025-12-17
Hill Malcolm R	Director	20	$0	$0	2025-12-17
D'Onofrio Matthew J	President & Chief Op. Officer	44	$0	$134.1K	2025-12-17
REED VICKIE S	Director	9	$0	$0	2025-12-17
WIDDER KENNETH J	Director, 10% Owner	26	$1.30M	$0	2025-12-17
GARNER CAM L	Director	20	$0	$0	2025-12-17
Klein Roger M.	10% Owner	2	$0	$95.9K	2025-11-06
Gonyer David A	President and CEO	37	$0	$209.8K	2023-02-08
RHOADS ANN D	Director	9	$0	$0	2021-05-05
LVPMC, LLC	10% Owner	3	$1.18M	$0	2018-08-20
GLENN SCOTT L	Director	8	$0	$0	2018-04-26
DP VII ASSOCIATES LP	10% Owner	3	$0	$27.6K	2016-05-26
BLAIR JAMES C	10% Owner	11	$0	$1.63M	2016-05-26
VITULLO NICOLE	10% Owner	9	$0	$222.8K	2016-04-27
TREU JESSE I	10% Owner	7	$0	$108.9K	2016-04-27
DOVEY BRIAN H	10% Owner	9	$0	$273.0K	2016-04-20
DOMAIN PARTERS VII L P	10% Owner	6	$0	$388.4K	2016-04-11
Halak Brian K	10% Owner	5	$0	$1.4K	2015-08-18
LVP III Associates, L.P.	10% Owner	6	$0	$0	2013-09-30
SCHOEMAKER KATHLEEN K	10% Owner	4	$0	$0	2013-09-30

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
D'Onofrio Matthew J	Chief Executive Officer	D To issuer deriv	2025-12-17	2025-12-17	70,000	—	$0	0	SEC↗
D'Onofrio Matthew J	Chief Executive Officer	D To issuer deriv	2025-12-17	2025-12-17	64,840	—	$0	0	SEC↗
REED VICKIE S	Director	D To issuer deriv	2025-12-17	2025-12-17	1,250	—	$0	0	SEC↗
REED VICKIE S	Director	D To issuer deriv	2025-12-17	2025-12-17	1,250	—	$0	0	SEC↗
REED VICKIE S	Director	D To issuer deriv	2025-12-17	2025-12-17	5,833	—	$0	0	SEC↗
Brady Todd C	Director	D To issuer deriv	2025-12-17	2025-12-17	1,187	—	$0	0	SEC↗
Brady Todd C	Director	D To issuer deriv	2025-12-17	2025-12-17	1,218	—	$0	0	SEC↗
Brady Todd C	Director	D To issuer deriv	2025-12-17	2025-12-17	5,833	—	$0	0	SEC↗
Kowieski Mark	Chief Financial Officer	D To issuer deriv	2025-12-17	2025-12-17	13,000	—	$0	0	SEC↗
Kowieski Mark	Chief Financial Officer	D To issuer deriv	2025-12-17	2025-12-17	17,291	—	$0	0	SEC↗
WIDDER KENNETH J	Director	D To issuer deriv	2025-12-17	2025-12-17	5,833	—	$0	0	SEC↗
WIDDER KENNETH J	Director	D To issuer deriv	2025-12-17	2025-12-17	1,187	—	$0	0	SEC↗
WIDDER KENNETH J	Director	D To issuer deriv	2025-12-17	2025-12-17	1,187	—	$0	0	SEC↗
Hill Malcolm R	Director	D To issuer deriv	2025-12-17	2025-12-17	1,218	—	$0	0	SEC↗
Hill Malcolm R	Director	D To issuer deriv	2025-12-17	2025-12-17	5,833	—	$0	0	SEC↗
Hill Malcolm R	Director	D To issuer deriv	2025-12-17	2025-12-17	1,218	—	$0	0	SEC↗
GARNER CAM L	Director	D To issuer deriv	2025-12-17	2025-12-17	8,750	—	$0	0	SEC↗
GARNER CAM L	Director	D To issuer deriv	2025-12-17	2025-12-17	1,291	—	$0	0	SEC↗
GARNER CAM L	Director	D To issuer deriv	2025-12-17	2025-12-17	1,479	—	$0	0	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	D To issuer deriv	2025-12-17	2025-12-17	11,000	—	$0	0	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	D To issuer deriv	2025-12-17	2025-12-17	17,291	—	$0	0	SEC↗
Smeal Benjamin C.	Director	D To issuer deriv	2025-12-17	2025-12-17	5,833	—	$0	0	SEC↗
Smeal Benjamin C.	Director	D To issuer deriv	2025-12-17	2025-12-17	1,125	—	$0	0	SEC↗
PYSZCZYMUKA GREG	Director	D To issuer deriv	2025-12-17	2025-12-17	1,155	—	$0	0	SEC↗
PYSZCZYMUKA GREG	Director	D To issuer deriv	2025-12-17	2025-12-17	5,833	—	$0	0	SEC↗
Mack Daniel	10% Owner	J Other deriv	2025-12-17	2025-12-19	433,962	$11.00	$4.77M	0	SEC↗
Mack Daniel	10% Owner	J Other deriv	2025-12-17	2025-12-19	117,019	$4.71	$551.2K	0	SEC↗
Mack Daniel	10% Owner	J Other deriv	2025-12-17	2025-12-19	117,019	$4.71	$551.2K	0	SEC↗
Mack Daniel	10% Owner	J Other deriv	2025-12-17	2025-12-19	158,531	$10.99	$1.74M	0	SEC↗
Mack Daniel	10% Owner	J Other deriv	2025-12-17	2025-12-19	250,627	$10.99	$2.75M	0	SEC↗
Mack Daniel	10% Owner	J Other	2025-12-17	2025-12-19	148,153	$11.00	$1.63M	0	SEC↗
D'Onofrio Matthew J	Chief Executive Officer	U Tender	2025-12-16	2025-12-17	15,509	—	$0	0	SEC↗
Brady Todd C	Director	U Tender	2025-12-16	2025-12-17	27	—	$0	0	SEC↗
Kowieski Mark	Chief Financial Officer	U Tender	2025-12-16	2025-12-17	11,815	—	$0	0	SEC↗
Hill Malcolm R	Director	U Tender	2025-12-16	2025-12-17	133	—	$0	0	SEC↗
GARNER CAM L	Director	U Tender	2025-12-16	2025-12-17	2,330	—	$0	0	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	U Tender	2025-12-16	2025-12-17	360	—	$0	0	SEC↗
Klein Roger M.	10% Owner	S Sale	2025-11-06	2025-11-07	4,000	$10.65	$42.6K	125,000	SEC↗
Klein Roger M.	10% Owner	S Sale	2025-11-06	2025-11-07	5,000	$10.66	$53.3K	29,000	SEC↗
PYSZCZYMUKA GREG	Director	A Award deriv	2025-05-21	2025-05-22	1,155	—	$0	6,988	SEC↗
Smeal Benjamin C.	Director	A Award deriv	2025-05-21	2025-05-22	1,125	—	$0	6,958	SEC↗
WIDDER KENNETH J	Director	A Award deriv	2025-05-21	2025-05-22	1,187	—	$0	8,207	SEC↗
REED VICKIE S	Director	A Award deriv	2025-05-21	2025-05-22	1,250	—	$0	8,333	SEC↗
GARNER CAM L	Director	A Award deriv	2025-05-21	2025-05-22	1,291	—	$0	11,520	SEC↗
Hill Malcolm R	Director	A Award deriv	2025-05-21	2025-05-22	1,218	—	$0	8,269	SEC↗
Brady Todd C	Director	A Award deriv	2025-05-21	2025-05-22	1,187	—	$0	8,238	SEC↗
D'Onofrio Matthew J	Chief Executive Officer	A Award	2025-03-21	2025-03-24	1,000	$2.80	$2.8K	9,820	SEC↗
Kowieski Mark	Chief Financial Officer	A Award	2025-03-20	2025-03-24	4,500	$3.21	$14.4K	4,916	SEC↗
D'Onofrio Matthew J	Chief Executive Officer	A Award	2025-02-28	2025-03-03	6,849	$3.65	$25.0K	8,820	SEC↗
PYSZCZYMUKA GREG	Director	A Award deriv	2025-02-20	2025-02-24	5,833	—	$0	5,833	SEC↗
REED VICKIE S	Director	A Award deriv	2025-01-28	2025-01-29	5,833	—	$0	5,833	SEC↗
Brady Todd C	Director	A Award deriv	2025-01-28	2025-01-29	5,833	—	$0	5,833	SEC↗
D'Onofrio Matthew J	Chief Executive Officer	A Award deriv	2025-01-28	2025-01-29	70,000	—	$0	70,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2025-01-28	2025-01-29	11,000	—	$0	11,000	SEC↗
Kowieski Mark	Chief Financial Officer	A Award deriv	2025-01-28	2025-01-29	13,000	—	$0	13,000	SEC↗
GARNER CAM L	Director	A Award deriv	2025-01-28	2025-01-29	8,750	—	$0	8,750	SEC↗
Hill Malcolm R	Director	A Award deriv	2025-01-28	2025-01-29	5,833	—	$0	5,833	SEC↗
WIDDER KENNETH J	Director	A Award deriv	2025-01-28	2025-01-29	5,833	—	$0	5,833	SEC↗
Mack Daniel	10% Owner	S Sale	2025-01-28	2025-01-30	41	$4.39	$180	148,153	SEC↗
Smeal Benjamin C.	Director	A Award deriv	2024-10-18	2024-10-22	5,833	—	$0	5,833	SEC↗
D'Onofrio Matthew J	Chief Executive Officer	A Award deriv	2024-08-07	2024-08-08	64,840	—	$0	64,840	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2024-08-07	2024-08-08	17,291	—	$0	17,291	SEC↗
Kowieski Mark	Chief Financial Officer	A Award deriv	2024-08-07	2024-08-08	17,291	—	$0	17,291	SEC↗
Brady Todd C	Director	A Award deriv	2024-05-22	2024-05-24	14,625	—	$0	14,625	SEC↗
WIDDER KENNETH J	Director	A Award deriv	2024-05-22	2024-05-24	14,250	—	$0	14,250	SEC↗
REED VICKIE S	Director	A Award deriv	2024-05-22	2024-05-24	15,000	—	$0	15,000	SEC↗
GARNER CAM L	Director	A Award deriv	2024-05-22	2024-05-24	17,750	—	$0	17,750	SEC↗
Hill Malcolm R	Director	A Award deriv	2024-05-22	2024-05-24	14,625	—	$0	14,625	SEC↗
Brady Todd C	Director	A Award deriv	2023-05-10	2023-05-11	14,625	—	$0	14,625	SEC↗
GARNER CAM L	Director	A Award deriv	2023-05-10	2023-05-11	17,750	—	$0	17,750	SEC↗
Hill Malcolm R	Director	A Award deriv	2023-05-10	2023-05-11	14,625	—	$0	14,625	SEC↗
REED VICKIE S	Director	A Award deriv	2023-05-10	2023-05-11	15,000	—	$0	15,000	SEC↗
WIDDER KENNETH J	Director	A Award deriv	2023-05-10	2023-05-11	14,250	—	$0	14,250	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2023-02-08	2023-02-10	15,000	—	$0	15,000	SEC↗
D'Onofrio Matthew J	President & Chief Op. Office	A Award deriv	2023-02-08	2023-02-10	25,000	—	$0	25,000	SEC↗
Gonyer David A	CEO	A Award deriv	2023-02-08	2023-02-10	30,000	—	$0	30,000	SEC↗
Brady Todd C	Director	A Award deriv	2022-04-27	2022-04-28	57,750	—	$0	57,750	SEC↗
GARNER CAM L	Director	A Award deriv	2022-04-27	2022-04-28	67,500	—	$0	67,500	SEC↗
Hill Malcolm R	Director	A Award deriv	2022-04-27	2022-04-28	57,750	—	$0	57,750	SEC↗
REED VICKIE S	Director	A Award deriv	2022-04-27	2022-04-28	58,000	—	$0	58,000	SEC↗
WIDDER KENNETH J	Director	A Award deriv	2022-04-27	2022-04-28	56,000	—	$0	56,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2022-02-02	2022-02-04	100,000	—	$0	100,000	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2022-02-02	2022-02-04	100,000	—	$0	100,000	SEC↗
Gonyer David A	President and CEO	A Award deriv	2022-02-02	2022-02-04	175,000	—	$0	175,000	SEC↗
REED VICKIE S	Director	A Award deriv	2021-05-13	2021-05-17	70,000	—	$0	70,000	SEC↗
GARNER CAM L	Director	A Award deriv	2021-05-05	2021-07-23	67,500	—	$0	67,500	SEC↗
Brady Todd C	Director	A Award deriv	2021-05-05	2021-07-23	57,750	—	$0	57,750	SEC↗
Hill Malcolm R	Director	A Award deriv	2021-05-05	2021-07-23	54,000	—	$0	54,000	SEC↗
RHOADS ANN D	Director	A Award deriv	2021-05-05	2021-07-23	61,750	—	$0	61,750	SEC↗
WIDDER KENNETH J	Director	A Award deriv	2021-05-05	2021-07-23	56,000	—	$0	56,000	SEC↗
	President and CEO	A Award deriv	2021-01-27	2021-01-29	415,000	—	$0	415,000	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2021-01-27	2021-01-29	300,000	—	$0	300,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2021-01-27	2021-01-29	300,000	—	$0	300,000	SEC↗
Gonyer David A	President and CEO	S Sale	2020-12-14	2020-12-14	23,954	$2.94	$70.4K	339,782	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	S Sale	2020-12-11	2020-12-14	40,357	$2.91	$117.4K	283,997	SEC↗
Gonyer David A	President and CEO	S Sale	2020-12-11	2020-12-14	48,046	$2.90	$139.3K	363,736	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	S Sale	2020-12-10	2020-12-14	5,643	$2.95	$16.6K	324,354	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	M Exercise deriv	2020-12-09	2020-12-11	46,000	—	$0	0	SEC↗
Gonyer David A	President and CEO	M Exercise deriv	2020-12-09	2020-12-11	72,000	—	$0	0	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	M Exercise	2020-12-09	2020-12-11	46,000	$0.40	$18.4K	329,997	SEC↗
Gonyer David A	President and CEO	M Exercise	2020-12-09	2020-12-11	72,000	$0.40	$28.8K	411,782	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	J Other	2020-09-01	2020-09-02	20,238	$1.05	$21.2K	283,997	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	J Other	2020-09-01	2020-09-02	20,238	$1.05	$21.2K	51,876	SEC↗
Gonyer David A	President and CEO	J Other	2020-09-01	2020-09-02	20,238	$1.05	$21.2K	339,782	SEC↗
Brady Todd C	Director	A Award deriv	2020-05-27	2020-05-29	57,750	—	$0	57,750	SEC↗
GARNER CAM L	Director	A Award deriv	2020-05-27	2020-05-29	67,500	—	$0	67,500	SEC↗
RHOADS ANN D	Director	A Award deriv	2020-05-27	2020-05-29	61,750	—	$0	61,750	SEC↗
WIDDER KENNETH J	Director	A Award deriv	2020-05-27	2020-05-29	56,000	—	$0	56,000	SEC↗
Hill Malcolm R	Director	A Award deriv	2020-05-27	2020-05-29	54,000	—	$0	54,000	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award	2020-03-02	2020-03-03	25,000	$0.85	$21.3K	263,759	SEC↗
Gonyer David A	President and CEO	A Award deriv	2020-02-28	2020-03-03	325,000	—	$0	325,000	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2020-02-28	2020-03-03	200,000	—	$0	200,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2020-02-28	2020-03-03	200,000	—	$0	200,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	D To issuer deriv	2019-06-17	2019-06-19	100,000	—	$0	0	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2019-06-17	2019-06-19	25,312	—	$0	25,312	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2019-06-17	2019-06-19	56,250	—	$0	56,250	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2019-06-17	2019-06-19	37,500	—	$0	37,500	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	D To issuer deriv	2019-06-17	2019-06-19	125,000	—	$0	0	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	D To issuer deriv	2019-06-17	2019-06-19	125,000	—	$0	0	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2019-06-17	2019-06-19	75,000	—	$0	75,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	D To issuer deriv	2019-06-17	2019-06-19	33,750	—	$0	0	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	D To issuer deriv	2019-06-17	2019-06-19	75,000	—	$0	0	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	D To issuer deriv	2019-06-17	2019-06-19	50,000	—	$0	0	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2019-06-17	2019-06-19	93,750	—	$0	93,750	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2019-06-17	2019-06-19	93,750	—	$0	93,750	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2019-06-17	2019-06-19	39,375	—	$0	39,375	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2019-06-17	2019-06-19	53,015	—	$0	53,015	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	D To issuer deriv	2019-06-17	2019-06-19	150,000	—	$0	0	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2019-06-17	2019-06-19	112,500	—	$0	112,500	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2019-06-17	2019-06-19	112,500	—	$0	112,500	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2019-06-17	2019-06-19	112,500	—	$0	112,500	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	D To issuer deriv	2019-06-17	2019-06-19	52,500	—	$0	0	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	D To issuer deriv	2019-06-17	2019-06-19	70,687	—	$0	0	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	D To issuer deriv	2019-06-17	2019-06-19	65,000	—	$0	0	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2019-06-17	2019-06-19	48,750	—	$0	48,750	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	D To issuer deriv	2019-06-17	2019-06-19	150,000	—	$0	0	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	D To issuer deriv	2019-06-17	2019-06-19	150,000	—	$0	0	SEC↗
Gonyer David A	President and CEO	D To issuer deriv	2019-06-17	2019-06-19	85,000	—	$0	0	SEC↗
Gonyer David A	President and CEO	D To issuer deriv	2019-06-17	2019-06-19	70,687	—	$0	0	SEC↗
Gonyer David A	President and CEO	D To issuer deriv	2019-06-17	2019-06-19	60,000	—	$0	0	SEC↗
Gonyer David A	President and CEO	D To issuer deriv	2019-06-17	2019-06-19	225,000	—	$0	0	SEC↗
Gonyer David A	President and CEO	D To issuer deriv	2019-06-17	2019-06-19	225,000	—	$0	0	SEC↗
Gonyer David A	President and CEO	D To issuer deriv	2019-06-17	2019-06-19	225,000	—	$0	0	SEC↗
Gonyer David A	President and CEO	A Award deriv	2019-06-17	2019-06-19	63,750	—	$0	63,750	SEC↗
Gonyer David A	President and CEO	A Award deriv	2019-06-17	2019-06-19	53,015	—	$0	53,015	SEC↗
Gonyer David A	President and CEO	A Award deriv	2019-06-17	2019-06-19	45,000	—	$0	45,000	SEC↗
Gonyer David A	President and CEO	A Award deriv	2019-06-17	2019-06-19	168,750	—	$0	168,750	SEC↗
Gonyer David A	President and CEO	A Award deriv	2019-06-17	2019-06-19	168,750	—	$0	168,750	SEC↗
Gonyer David A	President and CEO	A Award deriv	2019-06-17	2019-06-19	168,750	—	$0	168,750	SEC↗
Brady Todd C	Director	A Award deriv	2019-05-02	2019-05-03	34,000	—	$0	34,000	SEC↗
GARNER CAM L	Director	A Award deriv	2019-05-02	2019-05-03	37,500	—	$0	37,500	SEC↗
Hill Malcolm R	Director	A Award deriv	2019-05-02	2019-05-03	32,500	—	$0	32,500	SEC↗
RHOADS ANN D	Director	A Award deriv	2019-05-02	2019-05-03	36,500	—	$0	36,500	SEC↗
WIDDER KENNETH J	Director	A Award deriv	2019-05-02	2019-05-03	34,000	—	$0	34,000	SEC↗
Gonyer David A	President and CEO	A Award deriv	2019-02-06	2019-02-08	225,000	—	$0	225,000	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2019-02-06	2019-02-08	150,000	—	$0	150,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2019-02-06	2019-02-08	125,000	—	$0	125,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	J Other	2018-08-31	2018-09-05	3,101	$1.63	$5.1K	31,638	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	J Other	2018-08-31	2018-09-05	13,036	$1.63	$21.2K	238,759	SEC↗
Gonyer David A	President and CEO	J Other	2018-08-31	2018-09-05	6,901	$1.63	$11.2K	319,544	SEC↗
LVPMC, LLC	10% Owner	P Buy	2018-08-20	2018-08-21	11,628	$2.35	$27.3K	48,449	SEC↗
LVPMC, LLC	10% Owner	P Buy	2018-08-20	2018-08-21	23,256	$2.35	$54.7K	96,897	SEC↗
LVPMC, LLC	10% Owner	P Buy	2018-08-20	2018-08-21	465,116	$2.35	$1.09M	1,937,983	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2018-04-26	2018-04-27	125,000	—	$0	125,000	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2018-04-26	2018-04-27	150,000	—	$0	150,000	SEC↗
Gonyer David A	President and CEO	A Award deriv	2018-04-26	2018-04-27	225,000	—	$0	225,000	SEC↗
GARNER CAM L	Director	A Award deriv	2018-04-26	2018-04-27	37,500	—	$0	37,500	SEC↗
Brady Todd C	Director	A Award deriv	2018-04-26	2018-04-27	34,000	—	$0	34,000	SEC↗
GLENN SCOTT L	Director	A Award deriv	2018-04-26	2018-04-27	32,500	—	$0	32,500	SEC↗
Hill Malcolm R	Director	A Award deriv	2018-04-26	2018-04-27	31,500	—	$0	31,500	SEC↗
RHOADS ANN D	Director	A Award deriv	2018-04-26	2018-04-27	36,500	—	$0	36,500	SEC↗
WIDDER KENNETH J	Director	A Award deriv	2018-04-26	2018-04-27	34,000	—	$0	34,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	J Other	2017-08-31	2017-09-05	4,023	$2.15	$8.6K	28,537	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	J Other	2017-08-31	2017-09-05	1,115	$2.15	$2.4K	225,723	SEC↗
Gonyer David A	President and CEO	J Other	2017-08-31	2017-09-05	8,240	$2.15	$17.7K	312,643	SEC↗
GARNER CAM L	Director	A Award deriv	2017-05-03	2017-05-05	37,500	—	$0	37,500	SEC↗
Brady Todd C	Director	A Award deriv	2017-05-03	2017-05-05	34,000	—	$0	34,000	SEC↗
GLENN SCOTT L	Director	A Award deriv	2017-05-03	2017-05-05	32,500	—	$0	32,500	SEC↗
Hill Malcolm R	Director	A Award deriv	2017-05-03	2017-05-05	31,500	—	$0	31,500	SEC↗
RHOADS ANN D	Director	A Award deriv	2017-05-03	2017-05-05	36,500	—	$0	36,500	SEC↗
WIDDER KENNETH J	Director	A Award deriv	2017-05-03	2017-05-05	34,000	—	$0	34,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	J Other	2017-02-28	2017-03-02	7,875	$1.60	$12.6K	24,514	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	J Other	2017-02-28	2017-03-02	12,000	$1.60	$19.2K	224,608	SEC↗
Gonyer David A	President and CEO	J Other	2017-02-28	2017-03-02	12,000	$1.60	$19.2K	304,403	SEC↗
WIDDER KENNETH J	Director	P Buy	2017-02-22	2017-02-24	10,465	$2.90	$30.3K	36,821	SEC↗
WIDDER KENNETH J	Director	P Buy	2017-02-22	2017-02-24	20,930	$2.90	$60.7K	73,641	SEC↗
WIDDER KENNETH J	Director	P Buy	2017-02-22	2017-02-24	418,605	$2.90	$1.21M	1,472,867	SEC↗
Gonyer David A	President and CEO	A Award deriv	2017-01-25	2017-01-27	225,000	—	$0	225,000	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2017-01-25	2017-01-27	150,000	—	$0	150,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2017-01-25	2017-01-27	100,000	—	$0	100,000	SEC↗
BLAIR JAMES C	10% Owner	S Sale	2016-05-26	2016-05-27	344,120	$4.70	$1.62M	606,283	SEC↗
DP VII ASSOCIATES LP	10% Owner	S Sale	2016-05-26	2016-05-27	5,880	$4.70	$27.6K	10,328	SEC↗
GARNER CAM L	Director	A Award deriv	2016-04-27	2016-04-29	20,500	—	$0	20,500	SEC↗
Brady Todd C	Director	A Award deriv	2016-04-27	2016-04-29	19,000	—	$0	19,000	SEC↗
GLENN SCOTT L	Director	A Award deriv	2016-04-27	2016-04-29	17,500	—	$0	17,500	SEC↗
Hill Malcolm R	Director	A Award deriv	2016-04-27	2016-04-29	16,500	—	$0	16,500	SEC↗
RHOADS ANN D	Director	A Award deriv	2016-04-27	2016-04-29	21,500	—	$0	21,500	SEC↗
WIDDER KENNETH J	Director, 10% Owner	A Award deriv	2016-04-27	2016-04-29	19,000	—	$0	19,000	SEC↗
TREU JESSE I	10% Owner	S Sale	2016-04-27	2016-04-27	3,603	$5.02	$18.1K	950,403	SEC↗
VITULLO NICOLE	10% Owner	S Sale	2016-04-27	2016-04-27	61	$5.02	$306	16,208	SEC↗
TREU JESSE I	10% Owner	S Sale	2016-04-25	2016-04-27	1,492	$5.20	$7.8K	954,006	SEC↗
VITULLO NICOLE	10% Owner	S Sale	2016-04-25	2016-04-27	21	$5.20	$109	16,269	SEC↗
VITULLO NICOLE	10% Owner	S Sale	2016-04-20	2016-04-21	4,424	$5.29	$23.4K	955,498	SEC↗
DOVEY BRIAN H	10% Owner	S Sale	2016-04-20	2016-04-21	76	$5.29	$402	16,290	SEC↗
VITULLO NICOLE	10% Owner	S Sale	2016-04-19	2016-04-21	37,054	$5.36	$198.6K	959,922	SEC↗
DOVEY BRIAN H	10% Owner	S Sale	2016-04-19	2016-04-21	632	$5.36	$3.4K	16,366	SEC↗
DOMAIN PARTERS VII L P	10% Owner	S Sale	2016-04-11	2016-04-13	4,348	$5.22	$22.7K	996,976	SEC↗
VITULLO NICOLE	10% Owner	S Sale	2016-04-11	2016-04-13	75	$5.22	$392	16,998	SEC↗
DOVEY BRIAN H	10% Owner	S Sale	2016-04-08	2016-04-08	14,554	$5.35	$77.9K	1,001,324	SEC↗
BLAIR JAMES C	10% Owner	S Sale	2016-04-08	2016-04-08	251	$5.35	$1.3K	17,073	SEC↗
DOVEY BRIAN H	10% Owner	S Sale	2016-04-07	2016-04-08	27,781	$5.26	$146.1K	1,015,878	SEC↗
BLAIR JAMES C	10% Owner	S Sale	2016-04-07	2016-04-08	475	$5.26	$2.5K	17,324	SEC↗
DOVEY BRIAN H	10% Owner	S Sale	2016-04-06	2016-04-08	8,669	$5.22	$45.3K	1,043,659	SEC↗
BLAIR JAMES C	10% Owner	S Sale	2016-04-06	2016-04-08	148	$5.22	$773	17,799	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	J Other	2016-03-01	2016-03-01	7,331	$2.90	$21.3K	16,639	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	J Other	2016-03-01	2016-03-01	10,937	$2.90	$31.7K	212,608	SEC↗
Gonyer David A	President and CEO	J Other	2016-03-01	2016-03-01	4,669	$2.90	$13.5K	292,403	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	D To issuer deriv	2016-02-05	2016-02-05	100,000	—	$0	0	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	D To issuer deriv	2016-02-05	2016-02-05	45,000	—	$0	0	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2016-02-05	2016-02-05	75,000	—	$0	75,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2016-02-05	2016-02-05	33,750	—	$0	33,750	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2016-02-05	2016-02-05	52,500	—	$0	52,500	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	D To issuer deriv	2016-02-05	2016-02-05	94,250	—	$0	0	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	D To issuer deriv	2016-02-05	2016-02-05	70,000	—	$0	0	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2016-02-05	2016-02-05	70,687	—	$0	70,687	SEC↗
Gonyer David A	President and CEO	A Award deriv	2016-02-05	2016-02-05	60,000	—	$0	60,000	SEC↗
Gonyer David A	President and CEO	A Award deriv	2016-02-05	2016-02-05	70,687	—	$0	70,687	SEC↗
Gonyer David A	President and CEO	D To issuer deriv	2016-02-05	2016-02-05	80,000	—	$0	0	SEC↗
Gonyer David A	President and CEO	D To issuer deriv	2016-02-05	2016-02-05	94,250	—	$0	0	SEC↗
Gonyer David A	President and CEO	A Award deriv	2016-01-28	2016-01-29	85,000	—	$0	85,000	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2016-01-28	2016-01-29	65,000	—	$0	65,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2016-01-28	2016-01-29	50,000	—	$0	50,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	J Other	2015-08-31	2015-09-02	1,994	$3.31	$6.6K	9,308	SEC↗
Gonyer David A	President and CEO	J Other	2015-08-31	2015-09-02	4,023	$3.31	$13.3K	287,734	SEC↗
TREU JESSE I	10% Owner	S Sale	2015-08-18	2015-08-20	11,836	$7.02	$83.1K	1,052,328	SEC↗
Halak Brian K	10% Owner	S Sale	2015-08-18	2015-08-20	202	$7.02	$1.4K	17,947	SEC↗
Brady Todd C	Director	A Award deriv	2015-04-22	2015-04-24	9,000	—	$0	9,000	SEC↗
GARNER CAM L	Director	A Award deriv	2015-04-22	2015-04-24	9,000	—	$0	9,000	SEC↗
GLENN SCOTT L	Director	A Award deriv	2015-04-22	2015-04-24	9,000	—	$0	9,000	SEC↗
Hill Malcolm R	Director	A Award deriv	2015-04-22	2015-04-24	9,000	—	$0	9,000	SEC↗
RHOADS ANN D	Director	A Award deriv	2015-04-22	2015-04-24	9,000	—	$0	9,000	SEC↗
WIDDER KENNETH J	Director, 10% Owner	A Award deriv	2015-04-22	2015-04-24	9,000	—	$0	9,000	SEC↗
BLAIR JAMES C	10% Owner	S Sale	2015-04-16	2015-04-16	554	$7.07	$3.9K	18,149	SEC↗
DOMAIN PARTERS VII L P	10% Owner	S Sale	2015-04-16	2015-04-16	32,411	$7.07	$229.1K	1,064,164	SEC↗
BLAIR JAMES C	10% Owner	S Sale	2015-04-15	2015-04-16	135	$7.58	$1.0K	18,703	SEC↗
DOMAIN PARTERS VII L P	10% Owner	S Sale	2015-04-15	2015-04-16	7,920	$7.58	$60.0K	1,096,575	SEC↗
BLAIR JAMES C	10% Owner	S Sale	2015-04-14	2015-04-16	168	$7.78	$1.3K	18,838	SEC↗
DOMAIN PARTERS VII L P	10% Owner	S Sale	2015-04-14	2015-04-16	9,832	$7.78	$76.5K	1,104,495	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2015-03-06	2015-03-09	45,000	—	$0	45,000	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2015-03-06	2015-03-09	70,000	—	$0	70,000	SEC↗
Gonyer David A	President and CEO	A Award deriv	2015-03-06	2015-03-09	80,000	—	$0	80,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	J Other	2015-02-27	2015-03-02	6,058	$4.75	$28.8K	7,314	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	J Other	2015-02-27	2015-03-02	6,671	$4.75	$31.7K	201,671	SEC↗
Gonyer David A	President and CEO	J Other	2015-02-27	2015-03-02	2,711	$4.75	$12.9K	283,711	SEC↗
Brady Todd C	Director	P Buy	2014-09-23	2014-09-24	4,000	$5.70	$22.8K	4,000	SEC↗
Hill Malcolm R	Director	M Exercise deriv	2014-09-03	2014-09-03	5,250	—	$0	0	SEC↗
Hill Malcolm R	Director	M Exercise	2014-09-03	2014-09-03	5,250	$0.29	$1.5K	19,250	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	J Other	2014-08-29	2014-09-03	1,256	$5.67	$7.1K	1,256	SEC↗
Brady Todd C	Director	A Award deriv	2014-05-20	2014-05-22	9,000	—	$0	9,000	SEC↗
GARNER CAM L	Director	A Award deriv	2014-05-20	2014-05-22	9,000	—	$0	9,000	SEC↗
GLENN SCOTT L	Director	A Award deriv	2014-05-20	2014-05-22	9,000	—	$0	9,000	SEC↗
Hill Malcolm R	Director	A Award deriv	2014-05-20	2014-05-22	9,000	—	$0	9,000	SEC↗
RHOADS ANN D	Director	A Award deriv	2014-05-20	2014-05-22	9,000	—	$0	9,000	SEC↗
WIDDER KENNETH J	Director, 10% Owner	A Award deriv	2014-05-20	2014-05-22	9,000	—	$0	9,000	SEC↗
CARLSON MARILYN R.	Chief Medical Officer	A Award deriv	2013-12-02	2013-12-03	100,000	—	$0	100,000	SEC↗
D'Onofrio Matthew J	Exec VP, Chief Bus. Officer	A Award deriv	2013-12-02	2013-12-03	94,250	—	$0	94,250	SEC↗
Gonyer David A	President and CEO	A Award deriv	2013-12-02	2013-12-03	94,250	—	$0	94,250	SEC↗
GARNER CAM L	Director	C Conversion deriv	2013-09-30	2013-10-02	78,027	—	$0	0	SEC↗
GLENN SCOTT L	Director	C Conversion deriv	2013-09-30	2013-10-02	78,027	—	$0	0	SEC↗
LVP III Associates, L.P.	10% Owner	C Conversion deriv	2013-09-30	2013-10-02	263,566	—	$0	0	SEC↗
LVP III Associates, L.P.	10% Owner	C Conversion deriv	2013-09-30	2013-10-02	5,271,317	—	$0	0	SEC↗
LVP III Associates, L.P.	10% Owner	C Conversion deriv	2013-09-30	2013-10-02	131,784	—	$0	0	SEC↗
WIDDER KENNETH J	Director, 10% Owner	C Conversion deriv	2013-09-30	2013-10-02	131,784	—	$0	0	SEC↗
WIDDER KENNETH J	Director, 10% Owner	C Conversion deriv	2013-09-30	2013-10-02	263,556	—	$0	0	SEC↗
WIDDER KENNETH J	Director, 10% Owner	C Conversion deriv	2013-09-30	2013-10-02	5,271,317	—	$0	0	SEC↗
GARNER CAM L	Director	C Conversion	2013-09-30	2013-10-02	15,605	—	$0	335,605	SEC↗
GLENN SCOTT L	Director	C Conversion	2013-09-30	2013-10-02	15,605	—	$0	15,605	SEC↗
LVP III Associates, L.P.	10% Owner	C Conversion	2013-09-30	2013-10-02	26,356	—	$0	26,356	SEC↗
LVP III Associates, L.P.	10% Owner	C Conversion	2013-09-30	2013-10-02	1,054,262	—	$0	1,054,262	SEC↗
LVP III Associates, L.P.	10% Owner	C Conversion	2013-09-30	2013-10-02	52,711	—	$0	52,711	SEC↗
WIDDER KENNETH J	Director, 10% Owner	C Conversion	2013-09-30	2013-10-02	1,054,262	—	$0	1,054,262	SEC↗
WIDDER KENNETH J	Director, 10% Owner	C Conversion	2013-09-30	2013-10-02	52,711	—	$0	52,711	SEC↗
WIDDER KENNETH J	Director, 10% Owner	C Conversion	2013-09-30	2013-10-02	26,356	—	$0	26,356	SEC↗
DP VII ASSOCIATES LP	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	19,006	—	$0	0	SEC↗
DOMAIN PARTERS VII L P	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	1,114,327	—	$0	0	SEC↗
BLAIR JAMES C	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	19,006	—	$0	0	SEC↗
BLAIR JAMES C	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	1,114,327	—	$0	0	SEC↗
DOVEY BRIAN H	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	19,006	—	$0	0	SEC↗
DOVEY BRIAN H	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	1,114,327	—	$0	0	SEC↗
TREU JESSE I	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	19,006	—	$0	0	SEC↗
TREU JESSE I	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	1,114,327	—	$0	0	SEC↗
SCHOEMAKER KATHLEEN K	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	19,006	—	$0	0	SEC↗
SCHOEMAKER KATHLEEN K	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	1,114,327	—	$0	0	SEC↗
Halak Brian K	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	19,006	—	$0	0	SEC↗
Halak Brian K	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	1,114,327	—	$0	0	SEC↗
VITULLO NICOLE	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	1,114,327	—	$0	0	SEC↗
VITULLO NICOLE	10% Owner	C Conversion deriv	2013-09-30	2013-09-30	19,006	—	$0	0	SEC↗
DP VII ASSOCIATES LP	10% Owner	C Conversion	2013-09-30	2013-09-30	19,006	—	$0	19,006	SEC↗
DOMAIN PARTERS VII L P	10% Owner	C Conversion	2013-09-30	2013-09-30	1,114,327	—	$0	1,114,327	SEC↗
BLAIR JAMES C	10% Owner	C Conversion	2013-09-30	2013-09-30	1,114,327	—	$0	1,114,327	SEC↗