Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
$3.80M
38 trades · 5 insiders
Net · 90d
$-3.80M
Insiders on file
22
Daily buy vs sell · 90 days
■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Fox Jonathan C | Director | 14 | $300.4K | $0 | 2026-10-01 |
| Donovan Joanne M. | CMO | 61 | $0 | $6.15M | 2026-08-13 |
| Russell Alan J | Chief Scientific Officer, Director | 109 | $0 | $23.76M | 2026-08-12 |
| Derakhshan Behrad | Chief Business Officer | 57 | $0 | $2.28M | 2026-08-12 |
| Nofi Michael | Chief Financial Officer | 8 | $0 | $0 | 2026-08-12 |
| MOORE JOHN R | General Counsel | 127 | $0 | $4.67M | 2026-08-12 |
| KOCH KEVIN | President and CEO, Director | 47 | $0 | $2.13M | 2026-08-12 |
| Martin Christopher Nathan | Director | 2 | $0 | $0 | 2026-06-05 |
| Edris Badreddin | Director | 21 | $0 | $3.40M | 2026-06-05 |
| Brege Laura | Director | 5 | $0 | $0 | 2026-06-05 |
| Morris Arlene | Director | 4 | $0 | $0 | 2026-06-05 |
| Thompson Peter A. | Director, 10% Owner | 19 | $26.74M | $0 | 2026-06-05 |
| ROOT JONATHAN D | Director | 11 | $250.0K | $0 | 2026-06-05 |
| Blaustein Robert | Chief Development Officer | 4 | $0 | $0 | 2025-08-12 |
| Carruthers R Michael | Chief Financial Officer | 36 | $0 | $5.09M | 2025-08-12 |
| OrbiMed Genesis GP LLC | Director, 10% Owner | 3 | $15.00M | $0 | 2025-04-03 |
| Semigran Marc | Chief Development Officer | 8 | $0 | $881.9K | 2024-12-24 |
| OrbiMed Capital GP VI LLC | Director, 10% Owner | 2 | $5.99M | $0 | 2024-01-23 |
| Novo Holdings A/S | 10% Owner | 6 | $15.00M | $0 | 2022-09-14 |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | 10% Owner | 2 | $0 | $0 | 2021-03-30 |
| Deerfield Private Design Fund IV, L.P. | 10% Owner | 7 | $10.00M | $0 | 2021-03-30 |
| ORBIMED ADVISORS LLC | Director, 10% Owner | 9 | $5.75M | $0 | 2021-03-30 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Fox Jonathan C | Director | A Award | 2026-10-01 | 2026-10-02 | 308 | — | $0 | 25,141 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-08-13 | 2026-08-14 | 2,919 | $43.41 | $126.7K | 8,625 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-08-13 | 2026-08-14 | 2,919 | $43.41 | $126.7K | 8,625 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise deriv | 2026-08-12 | 2026-08-14 | 17,969 | — | $0 | 35,938 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise deriv | 2026-08-12 | 2026-08-14 | 21,875 | — | $0 | 65,625 | SEC↗ |
| KOCH KEVIN | President and CEO | A Award deriv | 2026-08-12 | 2026-08-14 | 100,000 | — | $0 | 100,000 | SEC↗ |
| KOCH KEVIN | President and CEO | A Award deriv | 2026-08-12 | 2026-08-14 | 200,000 | — | $0 | 200,000 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | A Award deriv | 2026-08-12 | 2026-08-14 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise deriv | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 11,563 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise deriv | 2026-08-12 | 2026-08-14 | 7,500 | — | $0 | 22,500 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | A Award deriv | 2026-08-12 | 2026-08-14 | 50,000 | — | $0 | 50,000 | SEC↗ |
| MOORE JOHN R | General Counsel | A Award deriv | 2026-08-12 | 2026-08-14 | 32,500 | — | $0 | 32,500 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise deriv | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 11,563 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise deriv | 2026-08-12 | 2026-08-14 | 6,718 | — | $0 | 20,157 | SEC↗ |
| MOORE JOHN R | General Counsel | A Award deriv | 2026-08-12 | 2026-08-14 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | A Award deriv | 2026-08-12 | 2026-08-14 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | A Award deriv | 2026-08-12 | 2026-08-14 | 32,500 | — | $0 | 32,500 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2026-08-12 | 2026-08-14 | 7,031 | — | $0 | 21,094 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 11,563 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise deriv | 2026-08-12 | 2026-08-14 | 7,031 | — | $0 | 21,094 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise deriv | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 11,563 | SEC↗ |
| Donovan Joanne M. | CMO | A Award deriv | 2026-08-12 | 2026-08-14 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Donovan Joanne M. | CMO | A Award deriv | 2026-08-12 | 2026-08-14 | 32,500 | — | $0 | 32,500 | SEC↗ |
| Nofi Michael | Chief Financial Officer | A Award deriv | 2026-08-12 | 2026-08-14 | 24,375 | — | $0 | 24,375 | SEC↗ |
| Nofi Michael | Chief Financial Officer | A Award deriv | 2026-08-12 | 2026-08-14 | 48,750 | — | $0 | 48,750 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | A Award deriv | 2026-08-12 | 2026-08-17 | 100,000 | — | $0 | 100,000 | SEC↗ |
| MOORE JOHN R | General Counsel | A Award deriv | 2026-08-12 | 2026-08-17 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | A Award deriv | 2026-08-12 | 2026-08-17 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Donovan Joanne M. | CMO | A Award deriv | 2026-08-12 | 2026-08-17 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Nofi Michael | Chief Financial Officer | A Award deriv | 2026-08-12 | 2026-08-17 | 48,750 | — | $0 | 48,750 | SEC↗ |
| KOCH KEVIN | President and CEO | S Sale | 2026-08-12 | 2026-08-14 | 913 | $44.33 | $40.5K | 52,488 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise | 2026-08-12 | 2026-08-14 | 17,969 | — | $0 | 48,584 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise | 2026-08-12 | 2026-08-14 | 21,875 | — | $0 | 70,459 | SEC↗ |
| KOCH KEVIN | President and CEO | S Sale | 2026-08-12 | 2026-08-14 | 8,782 | $43.64 | $383.2K | 61,677 | SEC↗ |
| KOCH KEVIN | President and CEO | S Sale | 2026-08-12 | 2026-08-14 | 8,276 | $43.66 | $361.3K | 53,401 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 29,426 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise | 2026-08-12 | 2026-08-14 | 7,500 | — | $0 | 36,926 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | S Sale | 2026-08-12 | 2026-08-14 | 2,171 | $43.79 | $95.1K | 34,755 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | S Sale | 2026-08-12 | 2026-08-14 | 304 | $44.50 | $13.5K | 34,451 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | S Sale | 2026-08-12 | 2026-08-14 | 2,475 | $43.70 | $108.2K | 31,826 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | S Sale | 2026-08-12 | 2026-08-14 | 150 | $44.44 | $6.7K | 34,301 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 15,995 | SEC↗ |
| MOORE JOHN R | General Counsel | S Sale | 2026-08-12 | 2026-08-14 | 2,419 | $43.80 | $106.0K | 17,697 | SEC↗ |
| MOORE JOHN R | General Counsel | S Sale | 2026-08-12 | 2026-08-14 | 99 | $44.50 | $4.4K | 20,116 | SEC↗ |
| MOORE JOHN R | General Counsel | S Sale | 2026-08-12 | 2026-08-14 | 59 | $44.41 | $2.6K | 20,215 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise | 2026-08-12 | 2026-08-14 | 6,718 | — | $0 | 22,713 | SEC↗ |
| MOORE JOHN R | General Counsel | S Sale | 2026-08-12 | 2026-08-14 | 2,439 | $43.81 | $106.9K | 20,274 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2026-08-12 | 2026-08-14 | 2,273 | $43.68 | $99.3K | 31,856 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2026-08-12 | 2026-08-14 | 390 | $44.46 | $17.3K | 31,466 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 30,336 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2026-08-12 | 2026-08-14 | 7,031 | — | $0 | 37,367 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2026-08-12 | 2026-08-14 | 3,238 | $43.68 | $141.4K | 34,129 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 11,035 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise | 2026-08-12 | 2026-08-14 | 7,031 | — | $0 | 18,066 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-08-12 | 2026-08-14 | 2,839 | $43.78 | $124.3K | 15,227 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-08-12 | 2026-08-14 | 2,779 | $43.71 | $121.5K | 12,448 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-08-12 | 2026-08-14 | 104 | $44.43 | $4.6K | 12,344 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-08-12 | 2026-08-14 | 800 | $44.52 | $35.6K | 11,544 | SEC↗ |
| Russell Alan J | Chief Scientific Officer, Di | A Award deriv | 2026-08-12 | 2026-08-14 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Russell Alan J | Chief Scientific Officer, Di | A Award deriv | 2026-08-12 | 2026-08-14 | 32,500 | — | $0 | 32,500 | SEC↗ |
| Russell Alan J | Chief Scientific Officer, Di | M Exercise deriv | 2026-08-12 | 2026-08-14 | 7,031 | — | $0 | 21,094 | SEC↗ |
| Russell Alan J | Chief Scientific Officer, Di | M Exercise deriv | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 11,563 | SEC↗ |
| Russell Alan J | Chief Scientific Officer, Di | S Sale | 2026-08-12 | 2026-08-14 | 390 | $44.46 | $17.3K | 31,466 | SEC↗ |
| Russell Alan J | Chief Scientific Officer, Di | S Sale | 2026-08-12 | 2026-08-14 | 2,273 | $43.68 | $99.3K | 31,856 | SEC↗ |
| Russell Alan J | Chief Scientific Officer, Di | S Sale | 2026-08-12 | 2026-08-14 | 3,238 | $43.68 | $141.4K | 34,129 | SEC↗ |
| Russell Alan J | Chief Scientific Officer, Di | M Exercise | 2026-08-12 | 2026-08-14 | 7,031 | — | $0 | 37,367 | SEC↗ |
| Russell Alan J | Chief Scientific Officer, Di | M Exercise | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 30,336 | SEC↗ |
| Nofi Michael | Chief Financial Officer | A Award deriv | 2026-08-12 | 2026-08-14 | 48,750 | — | $0 | 48,750 | SEC↗ |
| Nofi Michael | Chief Financial Officer | A Award deriv | 2026-08-12 | 2026-08-14 | 24,375 | — | $0 | 24,375 | SEC↗ |
| MOORE JOHN R | General Counsel | A Award deriv | 2026-08-12 | 2026-08-14 | 65,000 | — | $0 | 65,000 | SEC↗ |
| MOORE JOHN R | General Counsel | A Award deriv | 2026-08-12 | 2026-08-14 | 32,500 | — | $0 | 32,500 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise deriv | 2026-08-12 | 2026-08-14 | 6,718 | — | $0 | 20,157 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise deriv | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 11,563 | SEC↗ |
| MOORE JOHN R | General Counsel | S Sale | 2026-08-12 | 2026-08-14 | 2,419 | $43.80 | $105.9K | 17,697 | SEC↗ |
| MOORE JOHN R | General Counsel | S Sale | 2026-08-12 | 2026-08-14 | 99 | $44.50 | $4.4K | 20,116 | SEC↗ |
| MOORE JOHN R | General Counsel | S Sale | 2026-08-12 | 2026-08-14 | 59 | $44.41 | $2.6K | 20,215 | SEC↗ |
| MOORE JOHN R | General Counsel | S Sale | 2026-08-12 | 2026-08-14 | 2,439 | $43.81 | $106.8K | 20,274 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise | 2026-08-12 | 2026-08-14 | 6,718 | — | $0 | 22,713 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 15,995 | SEC↗ |
| KOCH KEVIN | President and CEO, Director | A Award deriv | 2026-08-12 | 2026-08-14 | 200,000 | — | $0 | 200,000 | SEC↗ |
| KOCH KEVIN | President and CEO, Director | A Award deriv | 2026-08-12 | 2026-08-14 | 100,000 | — | $0 | 100,000 | SEC↗ |
| KOCH KEVIN | President and CEO, Director | M Exercise deriv | 2026-08-12 | 2026-08-14 | 21,875 | — | $0 | 65,625 | SEC↗ |
| KOCH KEVIN | President and CEO, Director | M Exercise deriv | 2026-08-12 | 2026-08-14 | 17,969 | — | $0 | 35,938 | SEC↗ |
| KOCH KEVIN | President and CEO, Director | S Sale | 2026-08-12 | 2026-08-14 | 913 | $44.33 | $40.5K | 52,488 | SEC↗ |
| KOCH KEVIN | President and CEO, Director | S Sale | 2026-08-12 | 2026-08-14 | 8,276 | $43.66 | $361.3K | 53,401 | SEC↗ |
| KOCH KEVIN | President and CEO, Director | S Sale | 2026-08-12 | 2026-08-14 | 8,782 | $43.64 | $383.3K | 61,677 | SEC↗ |
| KOCH KEVIN | President and CEO, Director | M Exercise | 2026-08-12 | 2026-08-14 | 21,875 | — | $0 | 70,459 | SEC↗ |
| KOCH KEVIN | President and CEO, Director | M Exercise | 2026-08-12 | 2026-08-14 | 17,969 | — | $0 | 48,584 | SEC↗ |
| Donovan Joanne M. | CMO | A Award deriv | 2026-08-12 | 2026-08-14 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Donovan Joanne M. | CMO | A Award deriv | 2026-08-12 | 2026-08-14 | 32,500 | — | $0 | 32,500 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise deriv | 2026-08-12 | 2026-08-14 | 7,031 | — | $0 | 21,094 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise deriv | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 11,563 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-08-12 | 2026-08-14 | 800 | $44.52 | $35.6K | 11,544 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-08-12 | 2026-08-14 | 104 | $44.43 | $4.6K | 12,344 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-08-12 | 2026-08-14 | 2,779 | $43.71 | $121.5K | 12,448 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-08-12 | 2026-08-14 | 2,839 | $43.78 | $124.3K | 15,227 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise | 2026-08-12 | 2026-08-14 | 7,031 | — | $0 | 18,066 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 11,035 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | A Award deriv | 2026-08-12 | 2026-08-14 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | A Award deriv | 2026-08-12 | 2026-08-14 | 50,000 | — | $0 | 50,000 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise deriv | 2026-08-12 | 2026-08-14 | 7,500 | — | $0 | 22,500 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise deriv | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 11,563 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | S Sale | 2026-08-12 | 2026-08-14 | 2,475 | $43.70 | $108.2K | 31,826 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | S Sale | 2026-08-12 | 2026-08-14 | 150 | $44.44 | $6.7K | 34,301 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | S Sale | 2026-08-12 | 2026-08-14 | 304 | $44.50 | $13.5K | 34,451 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | S Sale | 2026-08-12 | 2026-08-14 | 2,171 | $43.79 | $95.1K | 34,755 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise | 2026-08-12 | 2026-08-14 | 7,500 | — | $0 | 36,926 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise | 2026-08-12 | 2026-08-14 | 5,781 | — | $0 | 29,426 | SEC↗ |
| Russell Alan J | Chief Scientific Officer, Di | A Award deriv | 2026-08-12 | 2026-08-17 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Nofi Michael | Chief Financial Officer | A Award deriv | 2026-08-12 | 2026-08-17 | 48,750 | — | $0 | 48,750 | SEC↗ |
| MOORE JOHN R | General Counsel | A Award deriv | 2026-08-12 | 2026-08-17 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Donovan Joanne M. | CMO | A Award deriv | 2026-08-12 | 2026-08-17 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | A Award deriv | 2026-08-12 | 2026-08-17 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2026-07-01 | 2026-07-02 | 69,648 | — | $0 | 1,077,717 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2026-07-01 | 2026-07-02 | 130,352 | — | $0 | 0 | SEC↗ |
| Fox Jonathan C | Director | A Award | 2026-07-01 | 2026-07-01 | 319 | — | $0 | 24,833 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2026-07-01 | 2026-07-02 | 130,352 | $39.41 | $5.14M | 94,203 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2026-07-01 | 2026-07-02 | 130,352 | $0.45 | $58.7K | 154,907 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2026-07-01 | 2026-07-02 | 69,648 | $0.18 | $12.5K | 224,555 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2026-07-01 | 2026-07-02 | 69,648 | $39.41 | $2.74M | 24,555 | SEC↗ |
| ROOT JONATHAN D | Director | A Award deriv | 2026-06-05 | 2026-07-17 | 16,377 | — | $0 | 16,377 | SEC↗ |
| Fox Jonathan C | Director | A Award deriv | 2026-06-05 | 2026-06-16 | 16,377 | — | $0 | 16,377 | SEC↗ |
| Martin Christopher Nathan | Director | A Award deriv | 2026-06-05 | 2026-06-16 | 16,377 | — | $0 | 16,377 | SEC↗ |
| Edris Badreddin | Director | A Award deriv | 2026-06-05 | 2026-06-16 | 5,619 | — | $0 | 5,619 | SEC↗ |
| Edris Badreddin | Director | A Award deriv | 2026-06-05 | 2026-06-16 | 8,188 | — | $0 | 8,188 | SEC↗ |
| Morris Arlene | Director | A Award deriv | 2026-06-05 | 2026-06-17 | 16,377 | — | $0 | 16,377 | SEC↗ |
| Thompson Peter A. | Director, 10% Owner | A Award deriv | 2026-06-05 | 2026-06-17 | 16,377 | — | $0 | 16,377 | SEC↗ |
| Brege Laura | Director | A Award deriv | 2026-06-05 | 2026-06-17 | 16,377 | — | $0 | 16,377 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise deriv | 2026-05-05 | 2026-05-05 | 50,000 | — | $0 | 75,000 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise | 2026-05-05 | 2026-05-05 | 50,000 | $7.08 | $354.0K | 54,367 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-05-05 | 2026-05-05 | 50,000 | $38.57 | $1.93M | 4,367 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-05-04 | 2026-05-05 | 5,230 | $31.29 | $163.6K | 4,367 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise deriv | 2026-04-01 | 2026-04-02 | 28,662 | — | $0 | 125,000 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-04-01 | 2026-04-02 | 28,662 | $32.31 | $926.1K | 9,597 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise | 2026-04-01 | 2026-04-02 | 28,662 | $7.08 | $202.9K | 38,259 | SEC↗ |
| Fox Jonathan C | Director | A Award | 2026-04-01 | 2026-04-03 | 339 | — | $0 | 24,514 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise deriv | 2026-03-31 | 2026-03-31 | 21,338 | — | $0 | 153,662 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise | 2026-03-31 | 2026-03-31 | 21,338 | $7.08 | $151.1K | 30,935 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-03-31 | 2026-03-31 | 21,338 | $32.12 | $685.4K | 9,597 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-03-27 | 2026-03-30 | 6,735 | $30.98 | $208.7K | 9,597 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2026-03-27 | 2026-03-30 | 9,623 | $30.98 | $298.1K | 16,332 | SEC↗ |
| Edris Badreddin | Director | M Exercise deriv | 2026-01-21 | 2026-01-23 | 10,463 | — | $0 | 0 | SEC↗ |
| Edris Badreddin | Director | M Exercise deriv | 2026-01-21 | 2026-01-23 | 7,605 | — | $0 | 0 | SEC↗ |
| Edris Badreddin | Director | M Exercise deriv | 2026-01-21 | 2026-01-23 | 17,236 | — | $0 | 0 | SEC↗ |
| Edris Badreddin | Director | M Exercise deriv | 2026-01-21 | 2026-01-23 | 13,690 | — | $0 | 0 | SEC↗ |
| Edris Badreddin | Director | M Exercise deriv | 2026-01-21 | 2026-01-23 | 66,477 | — | $0 | 0 | SEC↗ |
| Edris Badreddin | Director | S Sale | 2026-01-21 | 2026-01-23 | 7,605 | $29.44 | $223.9K | 96,760 | SEC↗ |
| Edris Badreddin | Director | S Sale | 2026-01-21 | 2026-01-23 | 17,236 | $29.44 | $507.4K | 104,365 | SEC↗ |
| Edris Badreddin | Director | S Sale | 2026-01-21 | 2026-01-23 | 10,463 | $29.44 | $308.0K | 86,297 | SEC↗ |
| Edris Badreddin | Director | S Sale | 2026-01-21 | 2026-01-23 | 66,477 | $29.44 | $1.96M | 19,820 | SEC↗ |
| Edris Badreddin | Director | M Exercise | 2026-01-21 | 2026-01-23 | 66,477 | $1.93 | $128.3K | 127,686 | SEC↗ |
| Edris Badreddin | Director | M Exercise | 2026-01-21 | 2026-01-23 | 13,690 | $0.39 | $5.3K | 33,510 | SEC↗ |
| Edris Badreddin | Director | M Exercise | 2026-01-21 | 2026-01-23 | 17,236 | $0.64 | $11.0K | 50,746 | SEC↗ |
| Edris Badreddin | Director | M Exercise | 2026-01-21 | 2026-01-23 | 10,463 | $1.93 | $20.2K | 61,209 | SEC↗ |
| Edris Badreddin | Director | M Exercise | 2026-01-21 | 2026-01-23 | 7,605 | $0.71 | $5.4K | 135,291 | SEC↗ |
| Edris Badreddin | Director | S Sale | 2026-01-21 | 2026-01-23 | 13,690 | $29.44 | $403.0K | 121,601 | SEC↗ |
| Fox Jonathan C | Director | A Award | 2026-01-02 | 2026-01-05 | 473 | — | $0 | 24,175 | SEC↗ |
| Martin Christopher Nathan | Director | A Award deriv | 2025-11-19 | 2025-11-24 | 45,150 | — | $0 | 45,150 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2025-11-12 | 2025-11-13 | 100,000 | — | $0 | 1,147,365 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2025-11-12 | 2025-11-13 | 100,000 | $0.18 | $18.0K | 123,400 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2025-11-12 | 2025-11-13 | 100,000 | $21.12 | $2.11M | 23,400 | SEC↗ |
| Fox Jonathan C | Director | P Buy | 2025-11-11 | 2025-11-13 | 10,700 | $18.64 | $199.4K | 23,702 | SEC↗ |
| Nofi Michael | Chief Financial Officer | A Award deriv | 2025-11-10 | 2025-11-13 | 262,500 | — | $0 | 262,500 | SEC↗ |
| Nofi Michael | Chief Financial Officer | A Award deriv | 2025-11-10 | 2025-11-13 | 43,750 | — | $0 | 43,750 | SEC↗ |
| Fox Jonathan C | Director | A Award | 2025-10-01 | 2025-10-02 | 728 | — | $0 | 13,002 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2025-08-26 | 2025-08-28 | 100,000 | — | $0 | 1,247,365 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2025-08-26 | 2025-08-28 | 100,000 | $0.18 | $18.0K | 123,400 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2025-08-26 | 2025-08-28 | 100,000 | $14.60 | $1.46M | 23,400 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise deriv | 2025-08-12 | 2025-08-14 | 5,781 | — | $0 | 17,344 | SEC↗ |
| Donovan Joanne M. | CMO | A Award deriv | 2025-08-12 | 2025-08-14 | 168,750 | — | $0 | 168,750 | SEC↗ |
| Donovan Joanne M. | CMO | A Award deriv | 2025-08-12 | 2025-08-14 | 28,125 | — | $0 | 28,125 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise deriv | 2025-08-12 | 2025-08-14 | 17,968 | — | $0 | 53,907 | SEC↗ |
| KOCH KEVIN | President and CEO | A Award deriv | 2025-08-12 | 2025-08-14 | 87,500 | — | $0 | 87,500 | SEC↗ |
| KOCH KEVIN | President and CEO | A Award deriv | 2025-08-12 | 2025-08-14 | 525,000 | — | $0 | 525,000 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | A Award deriv | 2025-08-12 | 2025-08-14 | 28,125 | — | $0 | 28,125 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2025-08-12 | 2025-08-14 | 5,781 | — | $0 | 17,344 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | A Award deriv | 2025-08-12 | 2025-08-14 | 168,750 | — | $0 | 168,750 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | A Award deriv | 2025-08-12 | 2025-08-14 | 161,250 | — | $0 | 161,250 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | M Exercise deriv | 2025-08-12 | 2025-08-14 | 5,781 | — | $0 | 17,344 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | A Award deriv | 2025-08-12 | 2025-08-14 | 26,875 | — | $0 | 26,875 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise deriv | 2025-08-12 | 2025-08-14 | 5,781 | — | $0 | 17,344 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | A Award deriv | 2025-08-12 | 2025-08-14 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | A Award deriv | 2025-08-12 | 2025-08-14 | 180,000 | — | $0 | 180,000 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise deriv | 2025-08-12 | 2025-08-14 | 5,781 | — | $0 | 17,344 | SEC↗ |
| MOORE JOHN R | General Counsel | A Award deriv | 2025-08-12 | 2025-08-14 | 161,250 | — | $0 | 161,250 | SEC↗ |
| MOORE JOHN R | General Counsel | A Award deriv | 2025-08-12 | 2025-08-14 | 26,875 | — | $0 | 26,875 | SEC↗ |
| Blaustein Robert | Chief Development Officer | A Award deriv | 2025-08-12 | 2025-08-14 | 17,500 | — | $0 | 17,500 | SEC↗ |
| Blaustein Robert | Chief Development Officer | A Award deriv | 2025-08-12 | 2025-08-14 | 105,000 | — | $0 | 105,000 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise | 2025-08-12 | 2025-08-14 | 5,781 | — | $0 | 28,223 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2025-08-12 | 2025-08-14 | 2,862 | $13.39 | $38.3K | 25,361 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise | 2025-08-12 | 2025-08-14 | 17,968 | — | $0 | 38,587 | SEC↗ |
| KOCH KEVIN | President and CEO | S Sale | 2025-08-12 | 2025-08-14 | 7,972 | $13.39 | $106.7K | 30,615 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2025-08-12 | 2025-08-14 | 5,781 | — | $0 | 25,307 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2025-08-12 | 2025-08-14 | 1,907 | $13.39 | $25.5K | 23,400 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | S Sale | 2025-08-12 | 2025-08-14 | 1,428 | $13.39 | $19.1K | 86,162 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | M Exercise | 2025-08-12 | 2025-08-14 | 5,781 | — | $0 | 87,590 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise | 2025-08-12 | 2025-08-14 | 5,781 | — | $0 | 26,136 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | S Sale | 2025-08-12 | 2025-08-14 | 2,491 | $13.39 | $33.4K | 23,645 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise | 2025-08-12 | 2025-08-14 | 5,781 | — | $0 | 12,312 | SEC↗ |
| MOORE JOHN R | General Counsel | S Sale | 2025-08-12 | 2025-08-14 | 2,098 | $13.39 | $28.1K | 10,214 | SEC↗ |
| Fox Jonathan C | Director | A Award | 2025-07-01 | 2025-07-02 | 858 | — | $0 | 12,274 | SEC↗ |
| Thompson Peter A. | Director, 10% Owner | A Award deriv | 2025-06-16 | 2025-06-18 | 30,000 | — | $0 | 30,000 | SEC↗ |
| ROOT JONATHAN D | Director | A Award deriv | 2025-06-16 | 2025-06-18 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Morris Arlene | Director | A Award deriv | 2025-06-16 | 2025-06-18 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Fox Jonathan C | Director | A Award deriv | 2025-06-16 | 2025-06-18 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Edris Badreddin | Director | A Award deriv | 2025-06-16 | 2025-06-18 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Brege Laura | Director | A Award deriv | 2025-06-16 | 2025-06-18 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | S Sale | 2025-05-02 | 2025-05-07 | 1,314 | $16.45 | $21.6K | 81,014 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | S Sale | 2025-05-02 | 2025-05-07 | 1,691 | $16.45 | $27.8K | 20,355 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2025-05-02 | 2025-05-07 | 5,187 | $16.45 | $85.3K | 21,588 | SEC↗ |
| KOCH KEVIN | President and CEO | S Sale | 2025-05-02 | 2025-05-07 | 4,276 | $16.45 | $70.3K | 20,619 | SEC↗ |
| MOORE JOHN R | General Counsel | S Sale | 2025-05-02 | 2025-05-07 | 1,930 | $16.45 | $31.7K | 6,531 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2025-05-02 | 2025-05-07 | 1,551 | $16.45 | $25.5K | 18,521 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | M Exercise deriv | 2025-05-01 | 2025-05-07 | 5,209 | — | $0 | 0 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise deriv | 2025-05-01 | 2025-05-07 | 5,209 | — | $0 | 0 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise deriv | 2025-05-01 | 2025-05-07 | 10,417 | — | $0 | 0 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise deriv | 2025-05-01 | 2025-05-07 | 10,417 | — | $0 | 0 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise deriv | 2025-05-01 | 2025-05-07 | 5,209 | — | $0 | 0 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2025-05-01 | 2025-05-07 | 5,209 | — | $0 | 0 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | M Exercise | 2025-05-01 | 2025-05-07 | 5,209 | — | $0 | 82,328 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise | 2025-05-01 | 2025-05-07 | 5,209 | — | $0 | 22,046 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise | 2025-05-01 | 2025-05-07 | 10,417 | — | $0 | 26,775 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise | 2025-05-01 | 2025-05-07 | 10,417 | — | $0 | 24,895 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise | 2025-05-01 | 2025-05-07 | 5,209 | — | $0 | 8,461 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2025-05-01 | 2025-05-07 | 5,209 | — | $0 | 20,072 | SEC↗ |
| OrbiMed Genesis GP LLC | Director, 10% Owner | P Buy | 2025-04-03 | 2025-04-04 | 372,578 | $20.13 | $7.50M | 14,809,075 | SEC↗ |
| OrbiMed Genesis GP LLC | Director, 10% Owner | P Buy | 2025-04-03 | 2025-04-04 | 124,193 | $20.13 | $2.50M | 443,792 | SEC↗ |
| Thompson Peter A. | Director, 10% Owner | P Buy | 2025-04-03 | 2025-04-04 | 124,193 | $20.13 | $2.50M | 443,792 | SEC↗ |
| Thompson Peter A. | Director, 10% Owner | P Buy | 2025-04-03 | 2025-04-04 | 372,578 | $20.13 | $7.50M | 14,809,075 | SEC↗ |
| Fox Jonathan C | Director | A Award | 2025-04-01 | 2025-04-03 | 559 | — | $0 | 11,416 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise deriv | 2025-03-07 | 2025-03-11 | 100 | — | $0 | 41,545 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2025-03-07 | 2025-03-11 | 200 | — | $0 | 1,456,580 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise | 2025-03-07 | 2025-03-11 | 100 | $0.18 | $18 | 14,578 | SEC↗ |
| KOCH KEVIN | President and CEO | S Sale | 2025-03-07 | 2025-03-11 | 100 | $30.00 | $3.0K | 14,478 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2025-03-07 | 2025-03-11 | 200 | $30.02 | $6.0K | 14,863 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2025-03-07 | 2025-03-11 | 200 | $0.18 | $36 | 15,063 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise deriv | 2025-02-06 | 2025-02-07 | 900 | — | $0 | 41,645 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2025-02-06 | 2025-02-07 | 1,200 | — | $0 | 1,347,565 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise | 2025-02-06 | 2025-02-07 | 900 | $13.11 | $11.8K | 15,378 | SEC↗ |
| KOCH KEVIN | President and CEO | S Sale | 2025-02-06 | 2025-02-07 | 900 | $31.13 | $28.0K | 14,478 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2025-02-06 | 2025-02-07 | 1,200 | $0.18 | $216 | 16,063 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2025-02-06 | 2025-02-07 | 1,200 | $30.13 | $36.2K | 14,863 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise deriv | 2025-02-05 | 2025-02-07 | 10,000 | — | $0 | 92,929 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise deriv | 2025-02-05 | 2025-02-07 | 8,636 | — | $0 | 42,545 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2025-02-05 | 2025-02-07 | 8,015 | — | $0 | 1,348,765 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | S Sale | 2025-02-05 | 2025-02-07 | 10,000 | $30.03 | $300.3K | 16,837 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise | 2025-02-05 | 2025-02-07 | 10,000 | $1.93 | $19.3K | 26,837 | SEC↗ |
| KOCH KEVIN | President and CEO | S Sale | 2025-02-05 | 2025-02-07 | 8,636 | $30.03 | $259.3K | 14,478 | SEC↗ |
| KOCH KEVIN | President and CEO | M Exercise | 2025-02-05 | 2025-02-07 | 8,636 | $0.18 | $1.6K | 23,114 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2025-02-05 | 2025-02-07 | 8,015 | $30.02 | $240.6K | 14,863 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2025-02-05 | 2025-02-07 | 8,015 | $0.18 | $1.4K | 22,878 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise deriv | 2025-01-28 | 2025-01-30 | 25,000 | — | $0 | 175,000 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2025-01-28 | 2025-01-30 | 25,000 | $27.63 | $690.8K | 16,358 | SEC↗ |
| Donovan Joanne M. | CMO | M Exercise | 2025-01-28 | 2025-01-30 | 25,000 | $7.08 | $177.0K | 41,358 | SEC↗ |
| Blaustein Robert | Chief Development Officer | A Award deriv | 2025-01-21 | 2025-01-23 | 160,000 | — | $0 | 160,000 | SEC↗ |
| Blaustein Robert | Chief Development Officer | A Award deriv | 2025-01-21 | 2025-01-23 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2024-12-30 | 2024-12-31 | 100,000 | — | $0 | 1,356,780 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2024-12-30 | 2024-12-31 | 100,000 | $27.37 | $2.74M | 14,863 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2024-12-30 | 2024-12-31 | 100,000 | $0.18 | $18.0K | 114,863 | SEC↗ |
| Semigran Marc | Chief Development Officer | M Exercise deriv | 2024-12-24 | 2024-12-27 | 29,709 | — | $0 | 270,291 | SEC↗ |
| Semigran Marc | Chief Development Officer | S Sale | 2024-12-24 | 2024-12-27 | 1,729 | $30.08 | $52.0K | 6,716 | SEC↗ |
| Semigran Marc | Chief Development Officer | M Exercise | 2024-12-24 | 2024-12-27 | 29,709 | $8.94 | $265.6K | 36,425 | SEC↗ |
| Semigran Marc | Chief Development Officer | S Sale | 2024-12-24 | 2024-12-27 | 27,980 | $29.66 | $829.9K | 8,445 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | M Exercise deriv | 2024-10-11 | 2024-10-16 | 70,000 | — | $0 | 127,122 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | M Exercise | 2024-10-11 | 2024-10-16 | 70,000 | $0.71 | $49.7K | 76,904 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise deriv | 2024-09-23 | 2024-09-24 | 20,922 | — | $0 | 41,636 | SEC↗ |
| MOORE JOHN R | General Counsel | S Sale | 2024-09-23 | 2024-09-24 | 20,922 | $27.63 | $578.1K | 3,252 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise | 2024-09-23 | 2024-09-24 | 20,922 | $0.71 | $14.9K | 24,174 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | M Exercise deriv | 2024-09-20 | 2024-09-24 | 96,068 | — | $0 | 40,990 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise deriv | 2024-09-20 | 2024-09-24 | 42,068 | — | $0 | 102,949 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise deriv | 2024-09-20 | 2024-09-24 | 50,000 | — | $0 | 62,558 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise deriv | 2024-09-20 | 2024-09-24 | 75,000 | — | $0 | 1,456,780 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | S Sale | 2024-09-20 | 2024-09-24 | 50,000 | $28.55 | $1.43M | 6,904 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | M Exercise | 2024-09-20 | 2024-09-24 | 50,000 | $1.93 | $96.5K | 56,904 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | S Sale | 2024-09-20 | 2024-09-24 | 24,960 | $28.59 | $713.6K | 6,904 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | S Sale | 2024-09-20 | 2024-09-24 | 4,064 | $28.59 | $116.2K | 31,864 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | S Sale | 2024-09-20 | 2024-09-24 | 46,068 | $28.59 | $1.32M | 35,928 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | M Exercise | 2024-09-20 | 2024-09-24 | 46,068 | $1.93 | $88.9K | 81,996 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | S Sale | 2024-09-20 | 2024-09-24 | 42,068 | $29.03 | $1.22M | 15,121 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | M Exercise | 2024-09-20 | 2024-09-24 | 42,068 | $1.93 | $81.2K | 57,189 | SEC↗ |
| Donovan Joanne M. | CMO | S Sale | 2024-09-20 | 2024-09-24 | 7,162 | $28.29 | $202.6K | 14,538 | SEC↗ |
| MOORE JOHN R | General Counsel | M Exercise | 2024-09-20 | 2024-09-24 | 50,000 | $0.71 | $35.5K | 53,252 | SEC↗ |
| MOORE JOHN R | General Counsel | S Sale | 2024-09-20 | 2024-09-24 | 50,000 | $28.37 | $1.42M | 3,252 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2024-09-20 | 2024-09-24 | 815 | $29.51 | $24.1K | 12,719 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | M Exercise | 2024-09-20 | 2024-09-24 | 75,000 | $0.18 | $13.5K | 87,719 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | S Sale | 2024-09-20 | 2024-09-24 | 74,185 | $28.25 | $2.10M | 13,534 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | A Award deriv | 2024-08-12 | 2024-08-14 | 23,125 | — | $0 | 23,125 | SEC↗ |
| Carruthers R Michael | Chief Financial Officer | A Award deriv | 2024-08-12 | 2024-08-14 | 138,750 | — | $0 | 138,750 | SEC↗ |
| Donovan Joanne M. | CMO | A Award deriv | 2024-08-12 | 2024-08-14 | 23,125 | — | $0 | 23,125 | SEC↗ |
| Donovan Joanne M. | CMO | A Award deriv | 2024-08-12 | 2024-08-14 | 138,750 | — | $0 | 138,750 | SEC↗ |
| KOCH KEVIN | President and CEO | A Award deriv | 2024-08-12 | 2024-08-14 | 71,875 | — | $0 | 71,875 | SEC↗ |
| KOCH KEVIN | President and CEO | A Award deriv | 2024-08-12 | 2024-08-14 | 431,250 | — | $0 | 431,250 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | A Award deriv | 2024-08-12 | 2024-08-14 | 138,750 | — | $0 | 138,750 | SEC↗ |
| Derakhshan Behrad | Chief Business Officer | A Award deriv | 2024-08-12 | 2024-08-14 | 23,125 | — | $0 | 23,125 | SEC↗ |
| MOORE JOHN R | General Counsel | A Award deriv | 2024-08-12 | 2024-08-14 | 138,750 | — | $0 | 138,750 | SEC↗ |
| MOORE JOHN R | General Counsel | A Award deriv | 2024-08-12 | 2024-08-14 | 23,125 | — | $0 | 23,125 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | A Award deriv | 2024-08-12 | 2024-08-14 | 138,750 | — | $0 | 138,750 | SEC↗ |
| Russell Alan J | Chief Scientific Officer | A Award deriv | 2024-08-12 | 2024-08-14 | 23,125 | — | $0 | 23,125 | SEC↗ |
| Semigran Marc | Chief Development Officer | A Award deriv | 2024-08-12 | 2024-08-14 | 23,125 | — | $0 | 23,125 | SEC↗ |
| Semigran Marc | Chief Development Officer | A Award deriv | 2024-08-12 | 2024-08-14 | 138,750 | — | $0 | 138,750 | SEC↗ |