Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$0
Insiders on file
33
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Michaud Charles Jr | See Remarks | 10 | $0 | $974 | 2024-03-25 |
| Alloway Paul | See Remarks | 18 | $0 | $24.3K | 2024-03-25 |
| TZIANABOS ARTHUR | President & CEO | 31 | $0 | $2.06M | 2024-01-09 |
| Seymour Albert | See remarks | 36 | $0 | $1.65M | 2023-09-06 |
| Jordan Julie | Chief Medical Officer | 12 | $0 | $2.7K | 2023-08-03 |
| Poulton Jeffrey V. | Director | 4 | $0 | $0 | 2023-06-14 |
| REICIN ALISE | Director | 5 | $0 | $0 | 2023-06-14 |
| Patterson Matthew R | Director | 6 | $0 | $0 | 2023-06-14 |
| Thistle Mary | Director | 6 | $0 | $0 | 2023-06-14 |
| GILLIS STEVEN | Director | 9 | $0 | $0 | 2023-06-14 |
| Blum Michael Lee | Chief Commercial Officer | 7 | $0 | $3.4K | 2023-02-23 |
| Smith W Bradford | See remarks | 48 | $0 | $1.27M | 2023-02-23 |
| PARMAR KUSH | Director, 10% Owner | 23 | $0 | $37.36M | 2022-06-15 |
| Gregory Richard J. | Director | 7 | $0 | $0 | 2022-06-15 |
| Kelly Timothy P | See Remarks. | 36 | $0 | $319.4K | 2022-02-24 |
| Cohn Gabriel | Chief Medical Officer | 7 | $0 | $6.3K | 2022-01-05 |
| 5AM Co-Investors IV, L.P. | 10% Owner | 4 | $0 | $17.03M | 2020-12-22 |
| Schwab Andrew J. | 10% Owner | 9 | $0 | $6.72M | 2020-12-14 |
| DEERFIELD PARTNERS, L.P. | 10% Owner | 2 | $0 | $8.02M | 2020-01-30 |
| Deerfield Mgmt III, L.P. | 10% Owner | 3 | $0 | $10.04M | 2020-01-28 |
| DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | Director, 10% Owner | 4 | $0 | $7.68M | 2019-12-24 |
| Deerfield Mgmt L.P. | Director, 10% Owner | 7 | $12.00M | $3.59M | 2019-12-23 |
| Rasty Siyamak | Chief Operating Officer | 3 | $0 | $321.8K | 2019-07-09 |
| Wheeler Cameron | Director | 3 | $0 | $0 | 2019-06-06 |
| ARCH Venture Fund VIII Overage, L.P. | 10% Owner | 1 | $0 | $0 | 2019-05-21 |
| ROCKLAGE SCOTT M | 10% Owner | 4 | $0 | $13.61M | 2019-05-16 |
| Rock Springs Capital Master Fund LP | 10% Owner | 3 | $4.00M | $0 | 2018-04-02 |
| Vida Ventures, LLC | 10% Owner | 3 | $6.00M | $0 | 2018-04-02 |
| Deerfield Mgmt HIF, L.P. | Director, 10% Owner | 10 | $20.00M | $0 | 2018-04-02 |
| Temasek Life Sciences Private Ltd | 10% Owner | 5 | $10.00M | $0 | 2018-04-02 |
| SHAH MAHENDRA | Director | 5 | $0 | $0 | 2018-04-02 |
| BYBEE CLINTON | 10% Owner | 3 | $0 | $0 | 2018-04-02 |
| NOVARTIS AG | 10% Owner | 2 | $0 | $0 | 2018-04-02 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Michaud Charles Jr | See Remarks | M Exercise deriv | 2024-03-25 | 2024-03-27 | 1,088 | — | $0 | 0 | SEC↗ |
| Michaud Charles Jr | See Remarks | M Exercise deriv | 2024-03-25 | 2024-03-27 | 5,360 | — | $0 | 0 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise deriv | 2024-03-25 | 2024-03-27 | 18,090 | — | $0 | 0 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise deriv | 2024-03-25 | 2024-03-27 | 5,440 | — | $0 | 0 | SEC↗ |
| Michaud Charles Jr | See Remarks | M Exercise | 2024-03-25 | 2024-03-27 | 6,448 | — | $0 | 18,046 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise | 2024-03-25 | 2024-03-27 | 23,530 | — | $0 | 51,566 | SEC↗ |
| TZIANABOS ARTHUR | Director | S Sale | 2024-01-09 | 2024-02-15 | 13,037 | $0.57 | $7.4K | 128,778 | SEC↗ |
| Michaud Charles Jr | See Remarks | S Sale | 2024-01-03 | 2024-01-05 | 1,708 | $0.57 | $974 | 11,598 | SEC↗ |
| Alloway Paul | See Remarks | S Sale | 2024-01-03 | 2024-01-05 | 7,280 | $0.57 | $4.1K | 28,036 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise deriv | 2024-01-01 | 2024-01-03 | 8,910 | — | $0 | 18,090 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise deriv | 2024-01-01 | 2024-01-03 | 4,420 | — | $0 | 0 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise deriv | 2024-01-01 | 2024-01-03 | 5,280 | — | $0 | 5,440 | SEC↗ |
| Michaud Charles Jr | See Remarks | M Exercise deriv | 2024-01-01 | 2024-01-03 | 1,056 | — | $0 | 1,088 | SEC↗ |
| Michaud Charles Jr | See Remarks | M Exercise deriv | 2024-01-01 | 2024-01-03 | 2,640 | — | $0 | 5,360 | SEC↗ |
| Michaud Charles Jr | See Remarks | M Exercise deriv | 2024-01-01 | 2024-01-03 | 544 | — | $0 | 0 | SEC↗ |
| TZIANABOS ARTHUR | Director | M Exercise deriv | 2024-01-01 | 2024-02-15 | 14,280 | — | $0 | 0 | SEC↗ |
| TZIANABOS ARTHUR | Director | M Exercise deriv | 2024-01-01 | 2024-02-15 | 19,140 | — | $0 | 19,720 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise | 2024-01-01 | 2024-01-03 | 8,910 | — | $0 | 35,316 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise | 2024-01-01 | 2024-01-03 | 4,420 | — | $0 | 21,126 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise | 2024-01-01 | 2024-01-03 | 5,280 | — | $0 | 26,406 | SEC↗ |
| Michaud Charles Jr | See Remarks | M Exercise | 2024-01-01 | 2024-01-03 | 1,056 | — | $0 | 10,666 | SEC↗ |
| Michaud Charles Jr | See Remarks | M Exercise | 2024-01-01 | 2024-01-03 | 2,640 | — | $0 | 13,306 | SEC↗ |
| Michaud Charles Jr | See Remarks | M Exercise | 2024-01-01 | 2024-01-03 | 544 | — | $0 | 9,610 | SEC↗ |
| TZIANABOS ARTHUR | Director | M Exercise | 2024-01-01 | 2024-02-15 | 14,280 | — | $0 | 122,675 | SEC↗ |
| TZIANABOS ARTHUR | Director | M Exercise | 2024-01-01 | 2024-02-15 | 19,140 | — | $0 | 141,815 | SEC↗ |
| Seymour Albert | See Remarks | M Exercise deriv | 2023-09-06 | 2023-09-08 | 4,620 | — | $0 | 9,380 | SEC↗ |
| Seymour Albert | See Remarks | S Sale | 2023-09-06 | 2023-09-08 | 1,448 | $1.15 | $1.7K | 150,874 | SEC↗ |
| Seymour Albert | See Remarks | M Exercise | 2023-09-06 | 2023-09-08 | 4,620 | — | $0 | 152,322 | SEC↗ |
| Jordan Julie | Chief Medical Officer | M Exercise deriv | 2023-08-03 | 2023-08-07 | 4,644 | — | $0 | 0 | SEC↗ |
| Jordan Julie | Chief Medical Officer | M Exercise deriv | 2023-08-03 | 2023-08-07 | 1,548 | — | $0 | 0 | SEC↗ |
| Jordan Julie | Chief Medical Officer | M Exercise deriv | 2023-08-03 | 2023-08-07 | 387 | — | $0 | 0 | SEC↗ |
| Jordan Julie | Chief Medical Officer | S Sale | 2023-08-03 | 2023-08-07 | 109 | $1.39 | $152 | 4,160 | SEC↗ |
| Jordan Julie | Chief Medical Officer | M Exercise | 2023-08-03 | 2023-08-07 | 387 | — | $0 | 4,269 | SEC↗ |
| Jordan Julie | Chief Medical Officer | S Sale | 2023-08-03 | 2023-08-07 | 1,308 | $1.39 | $1.8K | 7,496 | SEC↗ |
| Jordan Julie | Chief Medical Officer | M Exercise | 2023-08-03 | 2023-08-07 | 1,548 | — | $0 | 4,318 | SEC↗ |
| Jordan Julie | Chief Medical Officer | S Sale | 2023-08-03 | 2023-08-07 | 436 | $1.39 | $606 | 3,882 | SEC↗ |
| Jordan Julie | Chief Medical Officer | M Exercise | 2023-08-03 | 2023-08-07 | 4,644 | — | $0 | 8,804 | SEC↗ |
| Jordan Julie | Chief Medical Officer | M Exercise deriv | 2023-08-02 | 2023-08-04 | 350 | — | $0 | 0 | SEC↗ |
| Jordan Julie | Chief Medical Officer | M Exercise | 2023-08-02 | 2023-08-04 | 350 | — | $0 | 2,869 | SEC↗ |
| Jordan Julie | Chief Medical Officer | S Sale | 2023-08-02 | 2023-08-04 | 99 | $1.31 | $130 | 2,770 | SEC↗ |
| REICIN ALISE | Director | A Award deriv | 2023-06-14 | 2023-06-15 | 23,000 | — | $0 | 23,000 | SEC↗ |
| Poulton Jeffrey V. | Director | A Award deriv | 2023-06-14 | 2023-06-15 | 23,000 | — | $0 | 23,000 | SEC↗ |
| TZIANABOS ARTHUR | Director | A Award deriv | 2023-06-14 | 2023-06-15 | 23,000 | — | $0 | 23,000 | SEC↗ |
| Thistle Mary | Director | A Award deriv | 2023-06-14 | 2023-06-15 | 23,000 | — | $0 | 23,000 | SEC↗ |
| Patterson Matthew R | Director | A Award deriv | 2023-06-14 | 2023-06-15 | 23,000 | — | $0 | 23,000 | SEC↗ |
| GILLIS STEVEN | Director | A Award deriv | 2023-06-14 | 2023-06-15 | 23,000 | — | $0 | 23,000 | SEC↗ |
| Alloway Paul | See Remarks | S Sale | 2023-03-02 | 2023-03-06 | 10,965 | $1.45 | $15.9K | 16,706 | SEC↗ |
| Seymour Albert | See Remarks | A Award deriv | 2023-02-23 | 2023-02-27 | 105,000 | — | $0 | 105,000 | SEC↗ |
| Seymour Albert | See Remarks | A Award deriv | 2023-02-23 | 2023-02-27 | 632,000 | — | $0 | 632,000 | SEC↗ |
| Smith W Bradford | See remarks | A Award deriv | 2023-02-23 | 2023-02-27 | 36,000 | — | $0 | 36,000 | SEC↗ |
| Smith W Bradford | See remarks | A Award deriv | 2023-02-23 | 2023-02-27 | 213,000 | — | $0 | 213,000 | SEC↗ |
| Blum Michael Lee | Chief Commercial Officer | A Award deriv | 2023-02-23 | 2023-02-27 | 104,000 | — | $0 | 104,000 | SEC↗ |
| Blum Michael Lee | Chief Commercial Officer | A Award deriv | 2023-02-23 | 2023-02-27 | 17,000 | — | $0 | 17,000 | SEC↗ |
| Alloway Paul | See Remarks | A Award deriv | 2023-02-23 | 2023-02-27 | 27,000 | — | $0 | 27,000 | SEC↗ |
| Alloway Paul | See Remarks | A Award deriv | 2023-02-23 | 2023-02-27 | 164,000 | — | $0 | 164,000 | SEC↗ |
| TZIANABOS ARTHUR | Director | S Sale | 2023-01-09 | 2023-01-11 | 10,616 | $1.39 | $14.8K | 108,395 | SEC↗ |
| Seymour Albert | See Remarks | S Sale | 2023-01-09 | 2023-01-11 | 3,620 | $1.39 | $5.0K | 143,166 | SEC↗ |
| Smith W Bradford | See Remarks | S Sale | 2023-01-09 | 2023-01-11 | 3,729 | $1.39 | $5.2K | 14,219 | SEC↗ |
| Alloway Paul | See Remarks | S Sale | 2023-01-09 | 2023-01-11 | 3,090 | $1.39 | $4.3K | 20,103 | SEC↗ |
| Blum Michael Lee | Chief Commercial Officer | S Sale | 2023-01-09 | 2023-01-11 | 2,454 | $1.39 | $3.4K | 13,538 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise deriv | 2023-01-01 | 2023-01-04 | 4,290 | — | $0 | 4,420 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise deriv | 2023-01-01 | 2023-01-04 | 5,280 | — | $0 | 10,720 | SEC↗ |
| Smith W Bradford | See Remarks | M Exercise deriv | 2023-01-01 | 2023-01-04 | 6,930 | — | $0 | 14,070 | SEC↗ |
| Smith W Bradford | See Remarks | M Exercise deriv | 2023-01-01 | 2023-01-04 | 6,600 | — | $0 | 6,800 | SEC↗ |
| Seymour Albert | See Remarks | M Exercise deriv | 2023-01-01 | 2023-01-04 | 6,930 | — | $0 | 14,070 | SEC↗ |
| Seymour Albert | See Remarks | M Exercise deriv | 2023-01-01 | 2023-01-04 | 4,290 | — | $0 | 4,420 | SEC↗ |
| TZIANABOS ARTHUR | Director | M Exercise deriv | 2023-01-01 | 2023-01-04 | 19,140 | — | $0 | 38,860 | SEC↗ |
| TZIANABOS ARTHUR | Director | M Exercise deriv | 2023-01-01 | 2023-01-04 | 13,860 | — | $0 | 14,280 | SEC↗ |
| Blum Michael Lee | Chief Commercial Officer | M Exercise deriv | 2023-01-01 | 2023-01-04 | 4,950 | — | $0 | 10,050 | SEC↗ |
| Blum Michael Lee | Chief Commercial Officer | M Exercise deriv | 2023-01-01 | 2023-01-04 | 2,640 | — | $0 | 2,720 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise | 2023-01-01 | 2023-01-04 | 5,280 | — | $0 | 23,193 | SEC↗ |
| Alloway Paul | See Remarks | M Exercise | 2023-01-01 | 2023-01-04 | 4,290 | — | $0 | 17,913 | SEC↗ |
| Smith W Bradford | See Remarks | M Exercise | 2023-01-01 | 2023-01-04 | 6,930 | — | $0 | 17,948 | SEC↗ |
| Smith W Bradford | See Remarks | M Exercise | 2023-01-01 | 2023-01-04 | 6,600 | — | $0 | 11,018 | SEC↗ |
| Seymour Albert | See Remarks | M Exercise | 2023-01-01 | 2023-01-04 | 6,930 | — | $0 | 146,786 | SEC↗ |
| Seymour Albert | See Remarks | M Exercise | 2023-01-01 | 2023-01-04 | 4,290 | — | $0 | 139,856 | SEC↗ |
| TZIANABOS ARTHUR | Director | M Exercise | 2023-01-01 | 2023-01-04 | 19,140 | — | $0 | 119,011 | SEC↗ |
| TZIANABOS ARTHUR | Director | M Exercise | 2023-01-01 | 2023-01-04 | 13,860 | — | $0 | 99,871 | SEC↗ |
| Blum Michael Lee | Chief Commercial Officer | M Exercise | 2023-01-01 | 2023-01-04 | 2,640 | — | $0 | 11,042 | SEC↗ |
| Blum Michael Lee | Chief Commercial Officer | M Exercise | 2023-01-01 | 2023-01-04 | 4,950 | — | $0 | 15,992 | SEC↗ |
| Seymour Albert | See remarks | A Award deriv | 2022-09-06 | 2022-09-08 | 14,000 | — | $0 | 14,000 | SEC↗ |
| Seymour Albert | See remarks | A Award deriv | 2022-09-06 | 2022-09-08 | 23,000 | — | $0 | 23,000 | SEC↗ |
| PARMAR KUSH | Director | A Award deriv | 2022-06-15 | 2022-06-17 | 18,000 | — | $0 | 18,000 | SEC↗ |
| REICIN ALISE | Director | A Award deriv | 2022-06-15 | 2022-06-17 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Poulton Jeffrey V. | Director | A Award deriv | 2022-06-15 | 2022-06-17 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Gregory Richard J. | Director | A Award deriv | 2022-06-15 | 2022-06-17 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Thistle Mary | Director | A Award deriv | 2022-06-15 | 2022-06-17 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Patterson Matthew R | Director | A Award deriv | 2022-06-15 | 2022-06-17 | 18,000 | — | $0 | 18,000 | SEC↗ |
| GILLIS STEVEN | Director | A Award deriv | 2022-06-15 | 2022-06-17 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Seymour Albert | See Remarks | A Award deriv | 2022-04-21 | 2022-04-21 | 60,000 | — | $0 | 60,000 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | A Award deriv | 2022-02-24 | 2022-02-28 | 58,000 | — | $0 | 58,000 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | A Award deriv | 2022-02-24 | 2022-02-28 | 350,000 | — | $0 | 350,000 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | A Award deriv | 2022-02-24 | 2022-02-28 | 128,000 | — | $0 | 128,000 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | A Award deriv | 2022-02-24 | 2022-02-28 | 21,000 | — | $0 | 21,000 | SEC↗ |
| Kelly Timothy P | Chief Operating Officer | A Award deriv | 2022-02-24 | 2022-02-28 | 28,200 | — | $0 | 28,200 | SEC↗ |
| Kelly Timothy P | Chief Operating Officer | A Award deriv | 2022-02-24 | 2022-02-28 | 4,800 | — | $0 | 4,800 | SEC↗ |
| Smith W Bradford | CFO & Treasurer | A Award deriv | 2022-02-24 | 2022-02-28 | 126,000 | — | $0 | 126,000 | SEC↗ |
| Smith W Bradford | CFO & Treasurer | A Award deriv | 2022-02-24 | 2022-02-28 | 21,000 | — | $0 | 21,000 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | S Sale | 2022-01-05 | 2022-01-12 | 5,354 | $3.78 | $20.2K | 86,011 | SEC↗ |
| Cohn Gabriel | Chief Medical Officer | S Sale | 2022-01-05 | 2022-01-12 | 1,661 | $3.78 | $6.3K | 2,629 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2022-01-05 | 2022-01-12 | 1,661 | $3.78 | $6.3K | 131,646 | SEC↗ |
| Kelly Timothy P | Chief Operating Officer | S Sale | 2022-01-05 | 2022-01-12 | 1,406 | $3.78 | $5.3K | 2,224 | SEC↗ |
| Smith W Bradford | CFO & Treasurer | S Sale | 2022-01-05 | 2022-01-12 | 2,182 | $3.78 | $8.2K | 4,418 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | M Exercise deriv | 2022-01-01 | 2022-01-12 | 13,860 | — | $0 | 28,140 | SEC↗ |
| Cohn Gabriel | Chief Medical Officer | M Exercise deriv | 2022-01-01 | 2022-01-12 | 4,290 | — | $0 | 8,710 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | M Exercise deriv | 2022-01-01 | 2022-01-12 | 4,290 | — | $0 | 8,710 | SEC↗ |
| Kelly Timothy P | Chief Operating Officer | M Exercise deriv | 2022-01-01 | 2022-01-12 | 3,630 | — | $0 | 7,370 | SEC↗ |
| Smith W Bradford | CFO & Treasurer | M Exercise deriv | 2022-01-01 | 2022-01-12 | 6,600 | — | $0 | 13,400 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | M Exercise | 2022-01-01 | 2022-01-12 | 13,860 | — | $0 | 91,365 | SEC↗ |
| Cohn Gabriel | Chief Medical Officer | M Exercise | 2022-01-01 | 2022-01-12 | 4,290 | — | $0 | 4,290 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | M Exercise | 2022-01-01 | 2022-01-12 | 4,290 | — | $0 | 133,307 | SEC↗ |
| Kelly Timothy P | Chief Operating Officer | M Exercise | 2022-01-01 | 2022-01-12 | 3,630 | — | $0 | 3,630 | SEC↗ |
| Smith W Bradford | CFO & Treasurer | M Exercise | 2022-01-01 | 2022-01-12 | 6,600 | — | $0 | 6,600 | SEC↗ |
| Kelly Timothy P | See Remarks. | S Sale | 2021-09-03 | 2021-09-08 | 54 | $7.70 | $416 | 0 | SEC↗ |
| GILLIS STEVEN | Director | A Award deriv | 2021-06-17 | 2021-06-22 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Thistle Mary | Director | A Award deriv | 2021-06-17 | 2021-06-22 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Poulton Jeffrey V. | Director | A Award deriv | 2021-06-17 | 2021-06-22 | 18,000 | — | $0 | 18,000 | SEC↗ |
| REICIN ALISE | Director | A Award deriv | 2021-06-17 | 2021-06-22 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Patterson Matthew R | Director | A Award deriv | 2021-06-17 | 2021-06-22 | 18,000 | — | $0 | 18,000 | SEC↗ |
| PARMAR KUSH | Director | A Award deriv | 2021-06-17 | 2021-06-22 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Gregory Richard J. | Director | A Award deriv | 2021-06-17 | 2021-06-22 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Kelly Timothy P | Chief Operating Officer | A Award deriv | 2021-04-07 | 2021-04-09 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Kelly Timothy P | See Remarks | S Sale | 2021-03-01 | 2021-09-08 | 6,232 | $11.16 | $69.5K | 0 | SEC↗ |
| Kelly Timothy P | See Remarks. | M Exercise deriv | 2021-03-01 | 2021-03-03 | 2,000 | — | $0 | 41,500 | SEC↗ |
| Kelly Timothy P | See Remarks. | M Exercise deriv | 2021-03-01 | 2021-03-03 | 2,000 | — | $0 | 32,001 | SEC↗ |
| Kelly Timothy P | See Remarks. | M Exercise | 2021-03-01 | 2021-03-03 | 2,000 | $6.63 | $13.3K | 4,232 | SEC↗ |
| Kelly Timothy P | See Remarks. | S Sale | 2021-03-01 | 2021-03-03 | 6,232 | $11.16 | $69.5K | 0 | SEC↗ |
| Kelly Timothy P | See Remarks. | M Exercise | 2021-03-01 | 2021-03-03 | 2,000 | $2.89 | $5.8K | 6,232 | SEC↗ |
| Smith W Bradford | CFO & Treasurer | M Exercise deriv | 2021-02-08 | 2021-02-09 | 13,500 | — | $0 | 101,904 | SEC↗ |
| Smith W Bradford | CFO & Treasurer | M Exercise | 2021-02-08 | 2021-02-09 | 13,500 | $0.64 | $8.6K | 13,500 | SEC↗ |
| Smith W Bradford | CFO & Treasurer | S Sale | 2021-02-08 | 2021-02-09 | 13,500 | $14.25 | $192.4K | 0 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | A Award deriv | 2021-02-05 | 2021-02-09 | 42,000 | — | $0 | 42,000 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | A Award deriv | 2021-02-05 | 2021-02-09 | 254,000 | — | $0 | 254,000 | SEC↗ |
| Cohn Gabriel | Chief Medical Officer | A Award deriv | 2021-02-05 | 2021-02-09 | 78,000 | — | $0 | 78,000 | SEC↗ |
| Cohn Gabriel | Chief Medical Officer | A Award deriv | 2021-02-05 | 2021-02-09 | 13,000 | — | $0 | 13,000 | SEC↗ |
| Smith W Bradford | CFO & Treasurer | A Award deriv | 2021-02-05 | 2021-02-09 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Smith W Bradford | CFO & Treasurer | A Award deriv | 2021-02-05 | 2021-02-09 | 122,000 | — | $0 | 122,000 | SEC↗ |
| Kelly Timothy P | See Remarks | A Award deriv | 2021-02-05 | 2021-02-09 | 11,000 | — | $0 | 11,000 | SEC↗ |
| Kelly Timothy P | See Remarks | A Award deriv | 2021-02-05 | 2021-02-09 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | A Award deriv | 2021-02-05 | 2021-02-09 | 78,000 | — | $0 | 78,000 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | A Award deriv | 2021-02-05 | 2021-02-09 | 13,000 | — | $0 | 13,000 | SEC↗ |
| Kelly Timothy P | See Remarks | M Exercise deriv | 2021-02-02 | 2021-02-05 | 500 | — | $0 | 44,500 | SEC↗ |
| Kelly Timothy P | See Remarks | S Sale | 2021-02-02 | 2021-02-05 | 500 | $13.00 | $6.5K | 0 | SEC↗ |
| Kelly Timothy P | See Remarks | M Exercise | 2021-02-02 | 2021-02-05 | 500 | $6.63 | $3.3K | 500 | SEC↗ |
| Kelly Timothy P | See Remarks | M Exercise deriv | 2021-02-01 | 2021-02-03 | 2,000 | — | $0 | 34,001 | SEC↗ |
| Kelly Timothy P | See Remarks | M Exercise deriv | 2021-02-01 | 2021-02-03 | 2,000 | — | $0 | 43,500 | SEC↗ |
| Kelly Timothy P | See Remarks | S Sale | 2021-02-01 | 2021-02-03 | 4,000 | $12.37 | $49.5K | 0 | SEC↗ |
| Kelly Timothy P | See Remarks | M Exercise | 2021-02-01 | 2021-02-03 | 2,000 | $6.63 | $13.3K | 2,000 | SEC↗ |
| Kelly Timothy P | See Remarks | M Exercise | 2021-02-01 | 2021-02-03 | 2,000 | $2.89 | $5.8K | 4,000 | SEC↗ |
| Kelly Timothy P | See Remarks | M Exercise deriv | 2021-01-12 | 2021-01-14 | 500 | — | $0 | 45,000 | SEC↗ |
| Kelly Timothy P | See Remarks | M Exercise | 2021-01-12 | 2021-01-14 | 500 | $6.63 | $3.3K | 500 | SEC↗ |
| Kelly Timothy P | See Remarks | S Sale | 2021-01-12 | 2021-01-14 | 500 | $13.00 | $6.5K | 0 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2021-01-07 | 2021-01-08 | 5,103 | $12.05 | $61.5K | 129,017 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2021-01-06 | 2021-01-08 | 9,897 | $12.06 | $119.4K | 134,120 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2021-01-05 | 2021-01-07 | 10,000 | $11.44 | $114.4K | 144,017 | SEC↗ |
| Kelly Timothy P | See Remarks | M Exercise deriv | 2021-01-04 | 2021-01-06 | 2,000 | — | $0 | 45,500 | SEC↗ |
| Kelly Timothy P | See Remarks | M Exercise deriv | 2021-01-04 | 2021-01-06 | 2,000 | — | $0 | 36,001 | SEC↗ |
| Kelly Timothy P | See Remarks | M Exercise | 2021-01-04 | 2021-01-06 | 2,000 | $2.89 | $5.8K | 4,000 | SEC↗ |
| Kelly Timothy P | See Remarks | M Exercise | 2021-01-04 | 2021-01-06 | 2,000 | $6.63 | $13.3K | 2,000 | SEC↗ |
| Kelly Timothy P | See Remarks | S Sale | 2021-01-04 | 2021-01-06 | 4,000 | $11.50 | $46.0K | 0 | SEC↗ |
| 5AM Co-Investors IV, L.P. | 10% Owner | S Sale | 2020-12-22 | 2020-12-28 | 20,000 | $12.82 | $256.4K | 181,435 | SEC↗ |
| 5AM Co-Investors IV, L.P. | 10% Owner | S Sale | 2020-12-22 | 2020-12-28 | 480,000 | $12.82 | $6.15M | 4,354,484 | SEC↗ |
| PARMAR KUSH | Director | S Sale | 2020-12-22 | 2020-12-28 | 480,000 | $12.82 | $6.15M | 4,354,484 | SEC↗ |
| PARMAR KUSH | Director | S Sale | 2020-12-22 | 2020-12-28 | 20,000 | $12.82 | $256.4K | 181,435 | SEC↗ |
| Schwab Andrew J. | 10% Owner | S Sale | 2020-12-14 | 2020-12-16 | 328,862 | $11.88 | $3.91M | 4,834,484 | SEC↗ |
| Schwab Andrew J. | 10% Owner | S Sale | 2020-12-14 | 2020-12-16 | 151,138 | $13.06 | $1.97M | 5,163,346 | SEC↗ |
| Schwab Andrew J. | 10% Owner | S Sale | 2020-12-14 | 2020-12-16 | 13,703 | $11.88 | $162.8K | 201,435 | SEC↗ |
| Schwab Andrew J. | 10% Owner | S Sale | 2020-12-14 | 2020-12-16 | 6,297 | $13.06 | $82.2K | 215,138 | SEC↗ |
| PARMAR KUSH | Director | S Sale | 2020-12-14 | 2020-12-16 | 328,862 | $11.88 | $3.91M | 4,834,484 | SEC↗ |
| PARMAR KUSH | Director | S Sale | 2020-12-14 | 2020-12-16 | 6,297 | $13.06 | $82.2K | 215,138 | SEC↗ |
| PARMAR KUSH | Director | S Sale | 2020-12-14 | 2020-12-16 | 13,703 | $11.88 | $162.8K | 201,435 | SEC↗ |
| PARMAR KUSH | Director | S Sale | 2020-12-14 | 2020-12-16 | 151,138 | $13.06 | $1.97M | 5,163,346 | SEC↗ |
| Poulton Jeffrey V. | Director | A Award deriv | 2020-07-21 | 2020-07-21 | 36,000 | — | $0 | 36,000 | SEC↗ |
| GILLIS STEVEN | Director | A Award deriv | 2020-06-10 | 2020-06-12 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Patterson Matthew R | Director | A Award deriv | 2020-06-10 | 2020-06-12 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Thistle Mary | Director | A Award deriv | 2020-06-10 | 2020-06-12 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Gregory Richard J. | Director | A Award deriv | 2020-06-10 | 2020-06-12 | 18,000 | — | $0 | 18,000 | SEC↗ |
| PARMAR KUSH | Director, 10% Owner | A Award deriv | 2020-06-10 | 2020-06-12 | 18,000 | — | $0 | 18,000 | SEC↗ |
| REICIN ALISE | Director | A Award deriv | 2020-06-10 | 2020-06-12 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Kelly Timothy P | See Remarks | S Sale | 2020-03-17 | 2020-03-18 | 1,315 | $13.01 | $17.1K | 0 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise deriv | 2020-02-03 | 2020-02-05 | 12,000 | — | $0 | 103,404 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | S Sale | 2020-02-03 | 2020-02-05 | 12,500 | $16.16 | $202.0K | 77,505 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise | 2020-02-03 | 2020-02-05 | 12,000 | $0.63 | $7.6K | 12,000 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | S Sale | 2020-02-03 | 2020-02-05 | 12,000 | $16.16 | $193.9K | 0 | SEC↗ |
| DEERFIELD PARTNERS, L.P. | 10% Owner | S Sale | 2020-01-30 | 2020-01-31 | 509,970 | $15.45 | $7.88M | 0 | SEC↗ |
| DEERFIELD PARTNERS, L.P. | 10% Owner | S Sale | 2020-01-29 | 2020-01-31 | 8,857 | $15.45 | $136.8K | 509,970 | SEC↗ |
| Deerfield Mgmt III, L.P. | 10% Owner | S Sale | 2020-01-28 | 2020-01-28 | 65,891 | $15.51 | $1.02M | 518,827 | SEC↗ |
| Deerfield Mgmt III, L.P. | 10% Owner | S Sale | 2020-01-27 | 2020-01-28 | 193,359 | $15.77 | $3.05M | 584,718 | SEC↗ |
| Deerfield Mgmt III, L.P. | 10% Owner | S Sale | 2020-01-24 | 2020-01-28 | 380,256 | $15.69 | $5.97M | 778,077 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise deriv | 2020-01-02 | 2020-01-03 | 6,000 | — | $0 | 115,404 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | S Sale | 2020-01-02 | 2020-01-03 | 6,000 | $20.50 | $123.0K | 0 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise | 2020-01-02 | 2020-01-03 | 6,000 | $0.63 | $3.8K | 6,000 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2020-01-02 | 2020-01-03 | 9,133 | $20.50 | $187.2K | 154,017 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | S Sale | 2020-01-02 | 2020-01-03 | 12,500 | $20.50 | $256.3K | 90,005 | SEC↗ |
| DEERFIELD MANAGEMENT COMPANY, | 10% Owner | S Sale | 2019-12-24 | 2019-12-27 | 198,767 | $21.95 | $4.36M | 2,321,199 | SEC↗ |
| DEERFIELD MANAGEMENT COMPANY, | 10% Owner | S Sale | 2019-12-24 | 2019-12-27 | 151,233 | $21.95 | $3.32M | 1,766,106 | SEC↗ |
| Deerfield Mgmt L.P. | 10% Owner | S Sale | 2019-12-23 | 2019-12-23 | 56,595 | $21.83 | $1.24M | 1,917,339 | SEC↗ |
| Deerfield Mgmt L.P. | 10% Owner | S Sale | 2019-12-23 | 2019-12-23 | 74,384 | $21.83 | $1.62M | 2,519,966 | SEC↗ |
| Deerfield Mgmt L.P. | 10% Owner | S Sale | 2019-12-20 | 2019-12-23 | 9,130 | $21.50 | $196.3K | 1,973,934 | SEC↗ |
| Deerfield Mgmt L.P. | 10% Owner | S Sale | 2019-12-20 | 2019-12-23 | 11,999 | $21.50 | $258.0K | 2,594,350 | SEC↗ |
| Deerfield Mgmt L.P. | 10% Owner | S Sale | 2019-12-19 | 2019-12-23 | 5,454 | $21.68 | $118.2K | 1,983,064 | SEC↗ |
| Deerfield Mgmt L.P. | 10% Owner | S Sale | 2019-12-19 | 2019-12-23 | 7,168 | $21.68 | $155.4K | 2,606,349 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | A Award deriv | 2019-12-11 | 2019-12-13 | 111,000 | — | $0 | 111,000 | SEC↗ |
| Kelly Timothy P | See Remarks | A Award deriv | 2019-12-11 | 2019-12-13 | 112,000 | — | $0 | 112,000 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | A Award deriv | 2019-12-11 | 2019-12-13 | 110,000 | — | $0 | 110,000 | SEC↗ |
| Cohn Gabriel | Chief Medical Officer | A Award deriv | 2019-12-11 | 2019-12-13 | 15,000 | — | $0 | 15,000 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | A Award deriv | 2019-12-11 | 2019-12-13 | 358,000 | — | $0 | 358,000 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise deriv | 2019-12-02 | 2019-12-03 | 6,000 | — | $0 | 121,404 | SEC↗ |
| Cohn Gabriel | Chief Medical Officer | A Award deriv | 2019-12-02 | 2019-12-03 | 120,000 | — | $0 | 120,000 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2019-12-02 | 2019-12-03 | 9,300 | $16.23 | $150.9K | 163,150 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | S Sale | 2019-12-02 | 2019-12-03 | 12,500 | $16.25 | $203.1K | 102,505 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise | 2019-12-02 | 2019-12-03 | 6,000 | $0.64 | $3.8K | 6,000 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | S Sale | 2019-12-02 | 2019-12-03 | 6,000 | $16.21 | $97.3K | 0 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise deriv | 2019-11-29 | 2019-12-03 | 6,000 | — | $0 | 127,404 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2019-11-29 | 2019-12-03 | 9,300 | $16.06 | $149.4K | 172,450 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | S Sale | 2019-11-29 | 2019-12-03 | 12,500 | $16.04 | $200.5K | 115,005 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise | 2019-11-29 | 2019-12-03 | 6,000 | $0.64 | $3.8K | 6,000 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | S Sale | 2019-11-29 | 2019-12-03 | 6,000 | $16.00 | $96.0K | 0 | SEC↗ |
| Gregory Richard J. | Director | M Exercise deriv | 2019-11-18 | 2020-01-29 | 10,806 | — | $0 | 0 | SEC↗ |
| Gregory Richard J. | Director | M Exercise | 2019-11-18 | 2020-01-29 | 10,806 | $0.03 | $324 | 10,806 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise deriv | 2019-10-01 | 2019-10-02 | 6,000 | — | $0 | 133,404 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2019-10-01 | 2019-10-02 | 100 | $18.23 | $1.8K | 181,750 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2019-10-01 | 2019-10-02 | 9,200 | $17.38 | $159.9K | 181,850 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | S Sale | 2019-10-01 | 2019-10-02 | 12,400 | $17.39 | $215.6K | 127,605 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | S Sale | 2019-10-01 | 2019-10-02 | 100 | $18.23 | $1.8K | 127,505 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise | 2019-10-01 | 2019-10-02 | 6,000 | $0.64 | $3.8K | 6,000 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | S Sale | 2019-10-01 | 2019-10-02 | 100 | $18.23 | $1.8K | 0 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | S Sale | 2019-10-01 | 2019-10-02 | 5,900 | $17.38 | $102.5K | 100 | SEC↗ |
| Kelly Timothy P | See Remarks | S Sale | 2019-09-05 | 2019-09-09 | 1,166 | $19.94 | $23.3K | 0 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise deriv | 2019-09-03 | 2019-09-05 | 6,000 | — | $0 | 139,404 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | S Sale | 2019-09-03 | 2019-09-05 | 12,500 | $18.75 | $234.4K | 140,005 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2019-09-03 | 2019-09-05 | 9,300 | $18.74 | $174.3K | 191,050 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise | 2019-09-03 | 2019-09-05 | 6,000 | $0.64 | $3.8K | 6,000 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | S Sale | 2019-09-03 | 2019-09-05 | 6,000 | $18.74 | $112.4K | 0 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise deriv | 2019-08-01 | 2019-08-05 | 6,000 | — | $0 | 145,404 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | S Sale | 2019-08-01 | 2019-08-05 | 12,500 | $17.37 | $217.1K | 152,505 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise | 2019-08-01 | 2019-08-05 | 6,000 | $0.64 | $3.8K | 6,000 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | S Sale | 2019-08-01 | 2019-08-05 | 6,000 | $17.37 | $104.2K | 0 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2019-08-01 | 2019-08-05 | 9,300 | $17.37 | $161.5K | 200,350 | SEC↗ |
| REICIN ALISE | Director | A Award deriv | 2019-07-11 | 2019-07-15 | 31,160 | — | $0 | 31,160 | SEC↗ |
| Rasty Siyamak | Chief Operating Officer | S Sale | 2019-07-09 | 2019-07-11 | 8,000 | $20.00 | $160.0K | 222,707 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise deriv | 2019-07-01 | 2019-07-03 | 6,000 | — | $0 | 151,404 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | S Sale | 2019-07-01 | 2019-07-03 | 12,500 | $18.98 | $237.3K | 165,005 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | S Sale | 2019-07-01 | 2019-07-03 | 6,000 | $19.00 | $114.0K | 0 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise | 2019-07-01 | 2019-07-03 | 6,000 | $0.64 | $3.8K | 6,000 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2019-07-01 | 2019-07-03 | 9,200 | $18.98 | $174.6K | 209,750 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2019-07-01 | 2019-07-03 | 100 | $19.56 | $2.0K | 209,650 | SEC↗ |
| GILLIS STEVEN | Director | A Award deriv | 2019-06-06 | 2019-06-10 | 15,580 | — | $0 | 15,580 | SEC↗ |
| PARMAR KUSH | Director, 10% Owner | A Award deriv | 2019-06-06 | 2019-06-10 | 15,580 | — | $0 | 15,580 | SEC↗ |
| Patterson Matthew R | Director | A Award deriv | 2019-06-06 | 2019-06-10 | 15,580 | — | $0 | 15,580 | SEC↗ |
| Thistle Mary | Director | A Award deriv | 2019-06-06 | 2019-06-10 | 15,580 | — | $0 | 15,580 | SEC↗ |
| Wheeler Cameron | Director | A Award deriv | 2019-06-06 | 2019-06-10 | 15,580 | — | $0 | 15,580 | SEC↗ |
| Gregory Richard J. | Director | A Award deriv | 2019-06-06 | 2019-06-10 | 15,580 | — | $0 | 15,580 | SEC↗ |
| DEERFIELD MANAGEMENT COMPANY, | Director, 10% Owner | A Award deriv | 2019-06-06 | 2019-06-11 | 15,580 | — | $0 | 15,580 | SEC↗ |
| Wheeler Cameron | Director | A Award deriv | 2019-06-06 | 2019-06-11 | 15,580 | — | $0 | 15,580 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise deriv | 2019-06-03 | 2019-06-05 | 6,000 | — | $0 | 157,404 | SEC↗ |
| Rasty Siyamak | Chief Operating Officer | S Sale | 2019-06-03 | 2019-06-05 | 8,000 | $20.22 | $161.8K | 230,707 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | S Sale | 2019-06-03 | 2019-06-05 | 12,500 | $19.86 | $248.3K | 177,505 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | S Sale | 2019-06-03 | 2019-06-05 | 9,300 | $19.90 | $185.1K | 218,950 | SEC↗ |
| Kelly Timothy P | See Remarks | S Sale | 2019-06-03 | 2019-06-05 | 1,288 | $20.00 | $25.8K | 0 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | M Exercise | 2019-06-03 | 2019-06-05 | 6,000 | $0.64 | $3.8K | 6,000 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | S Sale | 2019-06-03 | 2019-06-05 | 6,000 | $19.94 | $119.6K | 0 | SEC↗ |
| ARCH Venture Fund VIII Overage | 10% Owner | J Other | 2019-05-21 | 2019-05-23 | 300,001 | — | $0 | 5,768,694 | SEC↗ |
| PARMAR KUSH | Director, 10% Owner | S Sale | 2019-05-16 | 2019-05-20 | 24,600 | $21.47 | $528.2K | 221,435 | SEC↗ |
| PARMAR KUSH | Director, 10% Owner | S Sale | 2019-05-16 | 2019-05-20 | 590,400 | $21.47 | $12.68M | 5,314,484 | SEC↗ |
| ROCKLAGE SCOTT M | 10% Owner | S Sale | 2019-05-16 | 2019-05-20 | 24,600 | $21.47 | $528.2K | 221,435 | SEC↗ |
| ROCKLAGE SCOTT M | 10% Owner | S Sale | 2019-05-16 | 2019-05-20 | 590,400 | $21.47 | $12.68M | 5,314,484 | SEC↗ |
| Deerfield Mgmt L.P. | Director, 10% Owner | P Buy | 2019-04-12 | 2019-04-15 | 533,333 | $22.50 | $12.00M | 1,158,333 | SEC↗ |
| Smith W Bradford | CFO, Treasurer & Secretary | A Award deriv | 2018-12-14 | 2018-12-18 | 88,000 | — | $0 | 88,000 | SEC↗ |
| TZIANABOS ARTHUR | President & CEO | A Award deriv | 2018-12-14 | 2018-12-18 | 203,000 | — | $0 | 203,000 | SEC↗ |
| Kelly Timothy P | See Remarks | A Award deriv | 2018-12-14 | 2018-12-18 | 66,000 | — | $0 | 66,000 | SEC↗ |
| Seymour Albert | Chief Scientific Officer | A Award deriv | 2018-12-14 | 2018-12-18 | 74,000 | — | $0 | 74,000 | SEC↗ |
| PARMAR KUSH | Director, 10% Owner | S Sale | 2018-12-10 | 2018-12-12 | 623 | $26.01 | $16.2K | 246,035 | SEC↗ |
| PARMAR KUSH | Director, 10% Owner | S Sale | 2018-12-10 | 2018-12-12 | 14,952 | $26.01 | $388.9K | 5,904,884 | SEC↗ |
| ROCKLAGE SCOTT M | 10% Owner | S Sale | 2018-12-10 | 2018-12-12 | 14,952 | $26.01 | $388.9K | 5,904,884 | SEC↗ |
| ROCKLAGE SCOTT M | 10% Owner | S Sale | 2018-12-10 | 2018-12-12 | 623 | $26.01 | $16.2K | 246,035 | SEC↗ |
| Schwab Andrew J. | 10% Owner | S Sale | 2018-11-23 | 2018-11-27 | 28,495 | $20.04 | $571.0K | 5,919,836 | SEC↗ |
| Schwab Andrew J. | 10% Owner | S Sale | 2018-11-23 | 2018-11-27 | 1,187 | $20.04 | $23.8K | 246,658 | SEC↗ |
| PARMAR KUSH | Director, 10% Owner | S Sale | 2018-11-23 | 2018-11-27 | 28,495 | $20.04 | $571.0K | 5,919,836 | SEC↗ |
| PARMAR KUSH | Director, 10% Owner | S Sale | 2018-11-23 | 2018-11-27 | 1,187 | $20.04 | $23.8K | 246,658 | SEC↗ |
| 5AM Co-Investors IV, L.P. | 10% Owner | S Sale | 2018-11-16 | 2018-11-20 | 504,864 | $20.20 | $10.20M | 5,948,331 | SEC↗ |
| 5AM Co-Investors IV, L.P. | 10% Owner | S Sale | 2018-11-16 | 2018-11-20 | 21,036 | $20.20 | $424.9K | 247,845 | SEC↗ |
| PARMAR KUSH | Director, 10% Owner | S Sale | 2018-11-16 | 2018-11-20 | 21,036 | $20.20 | $424.9K | 247,845 | SEC↗ |
| PARMAR KUSH | Director, 10% Owner | S Sale | 2018-11-16 | 2018-11-20 | 504,864 | $20.20 | $10.20M | 5,948,331 | SEC↗ |
| Temasek Life Sciences Private | 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 1,605,681 | — | $0 | 0 | SEC↗ |
| Temasek Life Sciences Private | 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 989,612 | — | $0 | 0 | SEC↗ |
| Vida Ventures, LLC | 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 395,845 | — | $0 | 0 | SEC↗ |
| Rock Springs Capital Master Fu | 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 395,845 | — | $0 | 0 | SEC↗ |
| NOVARTIS AG | 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 1,979,226 | — | $0 | 0 | SEC↗ |
| PARMAR KUSH | Director, 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 1,187,535 | — | $0 | 0 | SEC↗ |
| PARMAR KUSH | Director, 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 4,204,502 | — | $0 | 0 | SEC↗ |
| BYBEE CLINTON | 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 1,385,457 | — | $0 | 0 | SEC↗ |
| BYBEE CLINTON | 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 4,683,238 | — | $0 | 0 | SEC↗ |
| GILLIS STEVEN | Director | C Conversion deriv | 2018-04-02 | 2018-04-04 | 4,683,238 | — | $0 | 0 | SEC↗ |
| GILLIS STEVEN | Director | C Conversion deriv | 2018-04-02 | 2018-04-04 | 1,385,457 | — | $0 | 0 | SEC↗ |
| SHAH MAHENDRA | Director | C Conversion deriv | 2018-04-02 | 2018-04-04 | 659,742 | — | $0 | 0 | SEC↗ |
| Schwab Andrew J. | 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 1,187,535 | — | $0 | 0 | SEC↗ |
| Schwab Andrew J. | 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 4,204,502 | — | $0 | 0 | SEC↗ |
| Deerfield Mgmt HIF, L.P. | Director, 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 6,944,444 | — | $0 | 0 | SEC↗ |
| Deerfield Mgmt HIF, L.P. | Director, 10% Owner | C Conversion deriv | 2018-04-02 | 2018-04-04 | 6,944,445 | — | $0 | 0 | SEC↗ |