GHDX

GENOMIC HEALTH INCCIK 1131324 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for GHDX PRO

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AI insights for GHDX

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Hoof Torsten	Chief Int'l Commercial Officer	7	$0	$0	2019-11-08
Vaughn James J	Chief Commercial Officer	193	$0	$11.99M	2019-11-08
Radford Jason W.	Chief Legal Officer	34	$0	$1.19M	2019-11-08
McEachron Kim	Chief People Officer	32	$0	$1.19M	2019-11-08
Leber Laura	Chief Communication Officer	54	$0	$4.20M	2019-11-08
Pla Frederic	Chief Bus & Prod Dev Officer	72	$0	$5.59M	2019-11-08
Flannelly Barry P	Director	5	$0	$0	2019-11-08
Parker Geoffrey M.	Director	10	$0	$0	2019-11-08
Cohen Fred E	Director	82	$0	$3.63M	2019-11-08
Cole G Bradley	COO	380	$0	$25.11M	2019-11-08
Shak Steven	EVP of R&D & CMO	273	$0	$46.03M	2019-11-08
Popovits Kimberly J	President and CEO	342	$21.2K	$38.10M	2019-11-08
FUCHS HENRY J	Director	49	$0	$2.45M	2019-11-08
GRAHAM GINGER L	Director	62	$0	$0	2019-11-08
EXACT SCIENCES CORP	10% Owner	1	$0	$0	2019-11-08
667, L.P.	Director, 10% Owner	164	$14.14M	$58.81M	2019-10-01
BAKER JULIAN	Director, 10% Owner	109	$21.67M	$23.16M	2019-08-29
Baker Bros. Investments II, L.P.	Director, 10% Owner	49	$0	$11.52M	2019-07-01
14159, L.P.	Director, 10% Owner	128	$10.63M	$61.19M	2019-06-14
BAKER FELIX	Director, 10% Owner	155	$18.17M	$31.51M	2019-04-12
Baker Bros. Advisors (GP) LLC	Director, 10% Owner	42	$0	$45.19M	2019-03-19
Baker/Tisch Investments, LP	Director, 10% Owner	71	$0	$26.80M	2019-03-19
Baker Brothers Life Sciences LP	Director, 10% Owner	147	$32.32M	$49.22M	2019-03-14
Baker Bros. Investments, L.P.	Director, 10% Owner	96	$0	$14.58M	2019-03-11
BAKER BROS. ADVISORS LP	Director, 10% Owner	116	$36.28M	$19.88M	2019-02-27
Febbo Phillip G.	Chief Medical Officer	23	$0	$713.3K	2018-02-20
LIVINGSTON RANDALL S	Director	42	$0	$628.0K	2016-06-10
COLELLA SAMUEL D	Director	32	$0	$1.69M	2014-10-01
Schorno Dean L	CFO	82	$0	$1.88M	2014-06-10
HIBBS KATHY L	SVP & General Counsel	21	$0	$235.7K	2014-02-18
MYERS WOODROW A JR	Director	28	$0	$1.75M	2013-10-01
Scott Randal W	Executive Chairman	29	$0	$6.07M	2012-07-11
14159 capital (GP), LLC	Director, 10% Owner	4	$206.4K	$0	2012-03-05
Baker Brothers Life Sciences Capital (GP), LLC	Director, 10% Owner	9	$15.82M	$0	2012-03-05
Baker Joffre	Chief Scientific Officer	5	$0	$0	2012-02-15
Baker Biotech Capital (GP), LLC	Director, 10% Owner	9	$1.76M	$0	2012-02-10

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Popovits Kimberly J	President and CEO	D To issuer deriv	2019-11-08	2019-11-14	59,844	—	$0	0	SEC↗
Popovits Kimberly J	President and CEO	D To issuer deriv	2019-11-08	2019-11-14	131,656	—	$0	59,844	SEC↗
Popovits Kimberly J	President and CEO	D To issuer deriv	2019-11-08	2019-11-14	141,038	—	$0	12,822	SEC↗
Popovits Kimberly J	President and CEO	D To issuer deriv	2019-11-08	2019-11-14	100,000	—	$0	0	SEC↗
Popovits Kimberly J	President and CEO	D To issuer deriv	2019-11-08	2019-11-14	67,500	—	$0	0	SEC↗
Popovits Kimberly J	President and CEO	D To issuer deriv	2019-11-08	2019-11-14	12,822	—	$0	0	SEC↗
Popovits Kimberly J	President and CEO	D To issuer deriv	2019-11-08	2019-11-14	75,610	—	$0	0	SEC↗
Popovits Kimberly J	President and CEO	D To issuer deriv	2019-11-08	2019-11-14	92,869	—	$0	0	SEC↗
Popovits Kimberly J	President and CEO	D To issuer deriv	2019-11-08	2019-11-14	72,231	—	$0	92,869	SEC↗
Cole G Bradley	CFO	D To issuer deriv	2019-11-08	2019-11-14	29,436	—	$0	0	SEC↗
Cole G Bradley	CFO	D To issuer deriv	2019-11-08	2019-11-14	55,000	—	$0	0	SEC↗
Cole G Bradley	CFO	D To issuer deriv	2019-11-08	2019-11-14	20,000	—	$0	0	SEC↗
Cole G Bradley	CFO	D To issuer deriv	2019-11-08	2019-11-14	1,888	—	$0	0	SEC↗
Cole G Bradley	CFO	D To issuer deriv	2019-11-08	2019-11-14	27,740	—	$0	0	SEC↗
Cole G Bradley	CFO	D To issuer deriv	2019-11-08	2019-11-14	5,142	—	$0	0	SEC↗
Cole G Bradley	CFO	D To issuer deriv	2019-11-08	2019-11-14	38,582	—	$0	17,538	SEC↗
Cole G Bradley	CFO	D To issuer deriv	2019-11-08	2019-11-14	17,538	—	$0	0	SEC↗
Cole G Bradley	CFO	D To issuer deriv	2019-11-08	2019-11-14	22,894	—	$0	29,436	SEC↗
Cole G Bradley	CFO	D To issuer deriv	2019-11-08	2019-11-14	56,558	—	$0	5,142	SEC↗
Shak Steven	Chief Scientific Officer	D To issuer deriv	2019-11-08	2019-11-14	20,180	—	$0	0	SEC↗
Shak Steven	Chief Scientific Officer	D To issuer deriv	2019-11-08	2019-11-14	23,384	—	$0	0	SEC↗
Shak Steven	Chief Scientific Officer	D To issuer deriv	2019-11-08	2019-11-14	18,186	—	$0	23,384	SEC↗
Shak Steven	Chief Scientific Officer	D To issuer deriv	2019-11-08	2019-11-14	14,622	—	$0	0	SEC↗
Shak Steven	Chief Scientific Officer	D To issuer deriv	2019-11-08	2019-11-14	32,168	—	$0	14,622	SEC↗
Shak Steven	Chief Scientific Officer	D To issuer deriv	2019-11-08	2019-11-14	3,857	—	$0	0	SEC↗
Shak Steven	Chief Scientific Officer	D To issuer deriv	2019-11-08	2019-11-14	42,423	—	$0	3,857	SEC↗
Pla Frederic	COO	D To issuer deriv	2019-11-08	2019-11-14	29,544	—	$0	37,986	SEC↗
Pla Frederic	COO	D To issuer deriv	2019-11-08	2019-11-14	77,167	—	$0	0	SEC↗
Pla Frederic	COO	D To issuer deriv	2019-11-08	2019-11-14	28,570	—	$0	0	SEC↗
Pla Frederic	COO	D To issuer deriv	2019-11-08	2019-11-14	37,986	—	$0	0	SEC↗
Pla Frederic	COO	D To issuer deriv	2019-11-08	2019-11-14	12,625	—	$0	5,142	SEC↗
Pla Frederic	COO	D To issuer deriv	2019-11-08	2019-11-14	17,538	—	$0	0	SEC↗
Pla Frederic	COO	D To issuer deriv	2019-11-08	2019-11-14	24,864	—	$0	17,538	SEC↗
Pla Frederic	COO	D To issuer deriv	2019-11-08	2019-11-14	5,142	—	$0	0	SEC↗
Vaughn James J	Chief Commercial Officer	D To issuer deriv	2019-11-08	2019-11-14	16,900	—	$0	0	SEC↗
Vaughn James J	Chief Commercial Officer	D To issuer deriv	2019-11-08	2019-11-14	26,331	—	$0	0	SEC↗
Vaughn James J	Chief Commercial Officer	D To issuer deriv	2019-11-08	2019-11-14	13,376	—	$0	26,331	SEC↗
Vaughn James J	Chief Commercial Officer	D To issuer deriv	2019-11-08	2019-11-14	9,530	—	$0	0	SEC↗
Vaughn James J	Chief Commercial Officer	D To issuer deriv	2019-11-08	2019-11-14	18,027	—	$0	16,900	SEC↗
Vaughn James J	Chief Commercial Officer	D To issuer deriv	2019-11-08	2019-11-14	5,142	—	$0	0	SEC↗
Vaughn James J	Chief Commercial Officer	D To issuer deriv	2019-11-08	2019-11-14	17,739	—	$0	5,142	SEC↗
Radford Jason W.	Chief Legal Officer	D To issuer deriv	2019-11-08	2019-11-14	19,485	—	$0	0	SEC↗
Radford Jason W.	Chief Legal Officer	D To issuer deriv	2019-11-08	2019-11-14	12,000	—	$0	0	SEC↗
Radford Jason W.	Chief Legal Officer	D To issuer deriv	2019-11-08	2019-11-14	9,643	—	$0	877	SEC↗
Radford Jason W.	Chief Legal Officer	D To issuer deriv	2019-11-08	2019-11-14	877	—	$0	0	SEC↗
Radford Jason W.	Chief Legal Officer	D To issuer deriv	2019-11-08	2019-11-14	18,095	—	$0	8,225	SEC↗
Radford Jason W.	Chief Legal Officer	D To issuer deriv	2019-11-08	2019-11-14	8,225	—	$0	0	SEC↗
Radford Jason W.	Chief Legal Officer	D To issuer deriv	2019-11-08	2019-11-14	16,270	—	$0	0	SEC↗
Radford Jason W.	Chief Legal Officer	D To issuer deriv	2019-11-08	2019-11-14	15,155	—	$0	19,485	SEC↗
Hoof Torsten	Chief Int'l Commercial Offic	D To issuer deriv	2019-11-08	2019-11-14	10,950	—	$0	0	SEC↗
Hoof Torsten	Chief Int'l Commercial Offic	D To issuer deriv	2019-11-08	2019-11-14	5,750	—	$0	11,500	SEC↗
Hoof Torsten	Chief Int'l Commercial Offic	D To issuer deriv	2019-11-08	2019-11-14	11,500	—	$0	0	SEC↗
Hoof Torsten	Chief Int'l Commercial Offic	D To issuer deriv	2019-11-08	2019-11-14	1,980	—	$0	5,940	SEC↗
Hoof Torsten	Chief Int'l Commercial Offic	D To issuer deriv	2019-11-08	2019-11-14	5,940	—	$0	0	SEC↗
McEachron Kim	Chief People Officer	D To issuer deriv	2019-11-08	2019-11-14	9,838	—	$0	4,472	SEC↗
McEachron Kim	Chief People Officer	D To issuer deriv	2019-11-08	2019-11-14	10,040	—	$0	0	SEC↗
McEachron Kim	Chief People Officer	D To issuer deriv	2019-11-08	2019-11-14	9,000	—	$0	0	SEC↗
McEachron Kim	Chief People Officer	D To issuer deriv	2019-11-08	2019-11-14	13,484	—	$0	1,226	SEC↗
McEachron Kim	Chief People Officer	D To issuer deriv	2019-11-08	2019-11-14	1,226	—	$0	0	SEC↗
McEachron Kim	Chief People Officer	D To issuer deriv	2019-11-08	2019-11-14	6,562	—	$0	0	SEC↗
McEachron Kim	Chief People Officer	D To issuer deriv	2019-11-08	2019-11-14	4,472	—	$0	0	SEC↗
McEachron Kim	Chief People Officer	D To issuer deriv	2019-11-08	2019-11-14	7,621	—	$0	9,799	SEC↗
McEachron Kim	Chief People Officer	D To issuer deriv	2019-11-08	2019-11-14	9,799	—	$0	0	SEC↗
McEachron Kim	Chief People Officer	D To issuer deriv	2019-11-08	2019-11-14	9,530	—	$0	0	SEC↗
Leber Laura	Chief Communication Officer	D To issuer deriv	2019-11-08	2019-11-14	8,100	—	$0	0	SEC↗
Leber Laura	Chief Communication Officer	D To issuer deriv	2019-11-08	2019-11-14	11,250	—	$0	0	SEC↗
Leber Laura	Chief Communication Officer	D To issuer deriv	2019-11-08	2019-11-14	10,220	—	$0	0	SEC↗
Leber Laura	Chief Communication Officer	D To issuer deriv	2019-11-08	2019-11-14	9,000	—	$0	0	SEC↗
Leber Laura	Chief Communication Officer	D To issuer deriv	2019-11-08	2019-11-14	11,458	—	$0	1,042	SEC↗
Leber Laura	Chief Communication Officer	D To issuer deriv	2019-11-08	2019-11-14	1,042	—	$0	0	SEC↗
Leber Laura	Chief Communication Officer	D To issuer deriv	2019-11-08	2019-11-14	8,366	—	$0	3,804	SEC↗
Leber Laura	Chief Communication Officer	D To issuer deriv	2019-11-08	2019-11-14	3,804	—	$0	0	SEC↗
Leber Laura	Chief Communication Officer	D To issuer deriv	2019-11-08	2019-11-14	6,190	—	$0	7,960	SEC↗
Leber Laura	Chief Communication Officer	D To issuer deriv	2019-11-08	2019-11-14	7,960	—	$0	0	SEC↗
Leber Laura	Chief Communication Officer	D To issuer deriv	2019-11-08	2019-11-14	15,000	—	$0	0	SEC↗
GRAHAM GINGER L	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
GRAHAM GINGER L	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
GRAHAM GINGER L	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
GRAHAM GINGER L	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
GRAHAM GINGER L	Director	D To issuer deriv	2019-11-08	2019-11-14	6,583	—	$0	0	SEC↗
GRAHAM GINGER L	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
GRAHAM GINGER L	Director	D To issuer deriv	2019-11-08	2019-11-14	1,515	—	$0	0	SEC↗
GRAHAM GINGER L	Director	D To issuer deriv	2019-11-08	2019-11-14	8,250	—	$0	0	SEC↗
GRAHAM GINGER L	Director	D To issuer deriv	2019-11-08	2019-11-14	8,250	—	$0	0	SEC↗
Flannelly Barry P	Director	D To issuer deriv	2019-11-08	2019-11-14	20,000	—	$0	0	SEC↗
Cohen Fred E	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
Cohen Fred E	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
Cohen Fred E	Director	D To issuer deriv	2019-11-08	2019-11-14	6,583	—	$0	0	SEC↗
Cohen Fred E	Director	D To issuer deriv	2019-11-08	2019-11-14	1,515	—	$0	0	SEC↗
Cohen Fred E	Director	D To issuer deriv	2019-11-08	2019-11-14	8,250	—	$0	0	SEC↗
Cohen Fred E	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
Parker Geoffrey M.	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
Parker Geoffrey M.	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
Parker Geoffrey M.	Director	D To issuer deriv	2019-11-08	2019-11-14	6,583	—	$0	0	SEC↗
Parker Geoffrey M.	Director	D To issuer deriv	2019-11-08	2019-11-14	20,000	—	$0	0	SEC↗
FUCHS HENRY J	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
FUCHS HENRY J	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
FUCHS HENRY J	Director	D To issuer deriv	2019-11-08	2019-11-14	6,583	—	$0	0	SEC↗
FUCHS HENRY J	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
FUCHS HENRY J	Director	D To issuer deriv	2019-11-08	2019-11-14	10,000	—	$0	0	SEC↗
EXACT SCIENCES CORP	10% Owner	P Buy	2019-11-08	2019-11-13	37,643,330	—	$0	100	SEC↗
Popovits Kimberly J	President and CEO	D To issuer	2019-11-08	2019-11-14	36,168	—	$0	0	SEC↗
Popovits Kimberly J	President and CEO	D To issuer	2019-11-08	2019-11-14	68,268	—	$0	0	SEC↗
Popovits Kimberly J	President and CEO	D To issuer	2019-11-08	2019-11-14	12,298	—	$0	0	SEC↗
Cole G Bradley	CFO	D To issuer	2019-11-08	2019-11-14	11,794	—	$0	0	SEC↗
Cole G Bradley	CFO	D To issuer	2019-11-08	2019-11-14	27,385	—	$0	11,794	SEC↗
Shak Steven	Chief Scientific Officer	D To issuer	2019-11-08	2019-11-14	9,210	—	$0	0	SEC↗
Shak Steven	Chief Scientific Officer	D To issuer	2019-11-08	2019-11-14	49,585	—	$0	9,210	SEC↗
Pla Frederic	COO	D To issuer	2019-11-08	2019-11-14	18,510	—	$0	13,381	SEC↗
Pla Frederic	COO	D To issuer	2019-11-08	2019-11-14	13,381	—	$0	0	SEC↗
Vaughn James J	Chief Commercial Officer	D To issuer	2019-11-08	2019-11-14	11,281	—	$0	0	SEC↗
Vaughn James J	Chief Commercial Officer	D To issuer	2019-11-08	2019-11-14	5,249	—	$0	11,281	SEC↗
Radford Jason W.	Chief Legal Officer	D To issuer	2019-11-08	2019-11-14	20,924	—	$0	0	SEC↗
Radford Jason W.	Chief Legal Officer	D To issuer	2019-11-08	2019-11-14	8,384	—	$0	20,924	SEC↗
Hoof Torsten	Chief Int'l Commercial Offic	D To issuer	2019-11-08	2019-11-14	10,388	—	$0	0	SEC↗
Hoof Torsten	Chief Int'l Commercial Offic	D To issuer	2019-11-08	2019-11-14	4,479	—	$0	10,388	SEC↗
McEachron Kim	Chief People Officer	D To issuer	2019-11-08	2019-11-14	25,293	—	$0	11,261	SEC↗
McEachron Kim	Chief People Officer	D To issuer	2019-11-08	2019-11-14	11,261	—	$0	0	SEC↗
Leber Laura	Chief Communication Officer	D To issuer	2019-11-08	2019-11-14	9,384	—	$0	0	SEC↗
Leber Laura	Chief Communication Officer	D To issuer	2019-11-08	2019-11-14	4,352	—	$0	9,384	SEC↗
GRAHAM GINGER L	Director	D To issuer	2019-11-08	2019-11-14	955	—	$0	0	SEC↗
GRAHAM GINGER L	Director	D To issuer	2019-11-08	2019-11-14	52,349	—	$0	955	SEC↗
Flannelly Barry P	Director	D To issuer	2019-11-08	2019-11-14	397	—	$0	0	SEC↗
Cohen Fred E	Director	D To issuer	2019-11-08	2019-11-14	68,165	—	$0	955	SEC↗
Cohen Fred E	Director	D To issuer	2019-11-08	2019-11-14	955	—	$0	0	SEC↗
Cohen Fred E	Director	D To issuer	2019-11-08	2019-11-14	6,068	—	$0	0	SEC↗
Parker Geoffrey M.	Director	A Award	2019-11-08	2019-11-14	955	—	$0	0	SEC↗
FUCHS HENRY J	Director	D To issuer	2019-11-08	2019-11-14	6,878	—	$0	955	SEC↗
FUCHS HENRY J	Director	D To issuer	2019-11-08	2019-11-14	955	—	$0	0	SEC↗
Leber Laura	Chief Communication Officer	M Exercise deriv	2019-10-17	2019-10-21	13,183	—	$0	0	SEC↗
Leber Laura	Chief Communication Officer	S Sale	2019-10-17	2019-10-21	13,183	$70.94	$935.2K	13,736	SEC↗
Leber Laura	Chief Communication Officer	M Exercise	2019-10-17	2019-10-21	13,183	$22.98	$302.9K	26,919	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise deriv	2019-10-08	2019-10-09	4,500	—	$0	39,707	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-10-08	2019-10-09	10,000	$67.74	$677.4K	68,268	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-10-08	2019-10-09	4,500	$67.75	$304.9K	16,417	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise	2019-10-08	2019-10-09	4,500	$33.21	$149.4K	20,917	SEC↗
Cole G Bradley	CFO	M Exercise deriv	2019-10-07	2019-10-09	22,560	—	$0	20,000	SEC↗
Cole G Bradley	CFO	M Exercise	2019-10-07	2019-10-09	22,560	$30.84	$695.8K	61,530	SEC↗
Cole G Bradley	CFO	S Sale	2019-10-07	2019-10-09	22,560	$69.01	$1.56M	38,970	SEC↗
667, L.P.	Director, 10% Owner	A Award	2019-10-01	2019-10-03	370	$67.28	$24.9K	165,980	SEC↗
667, L.P.	Director, 10% Owner	A Award	2019-10-01	2019-10-03	370	$67.28	$24.9K	160,223	SEC↗
667, L.P.	Director, 10% Owner	A Award	2019-10-01	2019-10-03	370	$67.28	$24.9K	244,595	SEC↗
667, L.P.	Director, 10% Owner	A Award	2019-10-01	2019-10-03	370	$67.28	$24.9K	1,217,279	SEC↗
667, L.P.	Director, 10% Owner	A Award	2019-10-01	2019-10-03	370	$67.28	$24.9K	7,642,042	SEC↗
GRAHAM GINGER L	Director	A Award	2019-10-01	2019-10-03	185	$67.28	$12.4K	53,304	SEC↗
Cohen Fred E	Director	A Award	2019-10-01	2019-10-03	185	$67.28	$12.4K	69,120	SEC↗
Flannelly Barry P	Director	A Award	2019-10-01	2019-10-03	185	$67.28	$12.4K	397	SEC↗
FUCHS HENRY J	Director	A Award	2019-10-01	2019-10-03	185	$67.28	$12.4K	7,833	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-09-17	2019-09-19	25,000	$71.47	$1.79M	58,795	SEC↗
Cole G Bradley	CFO	M Exercise deriv	2019-09-10	2019-09-11	18,112	—	$0	1,888	SEC↗
Cole G Bradley	CFO	M Exercise	2019-09-10	2019-09-11	18,112	$28.05	$508.0K	57,082	SEC↗
Cole G Bradley	CFO	S Sale	2019-09-10	2019-09-11	13,303	$71.60	$952.5K	43,779	SEC↗
Cole G Bradley	CFO	S Sale	2019-09-10	2019-09-11	4,809	$72.33	$347.8K	38,970	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise deriv	2019-09-09	2019-09-11	1,500	—	$0	44,207	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise deriv	2019-09-09	2019-09-11	3,000	—	$0	0	SEC↗
Cole G Bradley	CFO	M Exercise deriv	2019-09-09	2019-09-11	25,000	—	$0	20,000	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-09-09	2019-09-11	1,300	$73.24	$95.2K	16,617	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-09-09	2019-09-11	200	$74.13	$14.8K	16,417	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise	2019-09-09	2019-09-11	3,000	$31.12	$93.4K	19,417	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-09-09	2019-09-11	3,000	$72.08	$216.2K	17,917	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise	2019-09-09	2019-09-11	1,500	$33.21	$49.8K	20,917	SEC↗
Cole G Bradley	CFO	M Exercise	2019-09-09	2019-09-11	25,000	$28.05	$701.3K	63,970	SEC↗
Cole G Bradley	CFO	S Sale	2019-09-09	2019-09-11	17,531	$72.10	$1.26M	46,439	SEC↗
Cole G Bradley	CFO	S Sale	2019-09-09	2019-09-11	5,707	$73.35	$418.6K	40,732	SEC↗
Cole G Bradley	CFO	S Sale	2019-09-09	2019-09-11	1,762	$74.00	$130.4K	38,970	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-09-09	2019-09-11	6,917	$72.10	$498.7K	81,351	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-09-09	2019-09-11	2,483	$73.35	$182.1K	78,868	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-09-09	2019-09-11	600	$74.10	$44.5K	78,268	SEC↗
BAKER JULIAN	Director, 10% Owner	G Gift	2019-08-29	2019-08-30	95,289	—	$0	0	SEC↗
BAKER JULIAN	Director, 10% Owner	J Other	2019-08-29	2019-08-30	7,815	—	$0	165,610	SEC↗
BAKER JULIAN	Director, 10% Owner	J Other	2019-08-29	2019-08-30	8,866	—	$0	43,361	SEC↗
BAKER JULIAN	Director, 10% Owner	J Other	2019-08-29	2019-08-30	8,340	—	$0	95,289	SEC↗
BAKER JULIAN	Director, 10% Owner	J Other	2019-08-29	2019-08-30	8,341	—	$0	95,289	SEC↗
BAKER JULIAN	Director, 10% Owner	G Gift	2019-08-29	2019-08-30	95,289	—	$0	0	SEC↗
Popovits Kimberly J	President and CEO	G Gift	2019-08-22	2019-09-11	10,200	—	$0	88,268	SEC↗
Pla Frederic	COO	M Exercise deriv	2019-08-19	2019-08-21	1,251	—	$0	42,402	SEC↗
Pla Frederic	COO	M Exercise	2019-08-19	2019-08-21	1,251	$27.48	$34.4K	33,142	SEC↗
Pla Frederic	COO	S Sale	2019-08-19	2019-08-21	1,251	$75.00	$93.8K	31,891	SEC↗
Radford Jason W.	Chief Legal Officer	S Sale	2019-08-15	2019-08-19	100	$74.80	$7.5K	29,295	SEC↗
Radford Jason W.	Chief Legal Officer	S Sale	2019-08-15	2019-08-19	2,081	$74.09	$154.2K	29,395	SEC↗
Popovits Kimberly J	President and CEO	M Exercise deriv	2019-08-13	2019-08-14	15,000	—	$0	0	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-08-13	2019-08-14	7,607	$74.68	$568.1K	108,468	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-08-13	2019-08-14	5,091	$74.67	$380.1K	98,468	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-08-13	2019-08-14	4,909	$73.72	$361.9K	103,559	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-08-13	2019-08-14	7,393	$73.72	$545.0K	116,075	SEC↗
Popovits Kimberly J	President and CEO	M Exercise	2019-08-13	2019-08-14	15,000	$29.34	$440.1K	123,468	SEC↗
Popovits Kimberly J	President and CEO	M Exercise deriv	2019-08-12	2019-08-14	25,000	—	$0	15,000	SEC↗
Cole G Bradley	CFO	M Exercise deriv	2019-08-12	2019-08-14	60,000	—	$0	0	SEC↗
Popovits Kimberly J	President and CEO	M Exercise	2019-08-12	2019-08-14	25,000	$29.34	$733.5K	133,468	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-08-12	2019-08-14	24,553	$73.30	$1.80M	108,915	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-08-12	2019-08-14	447	$73.76	$33.0K	108,468	SEC↗
Cole G Bradley	CFO	M Exercise	2019-08-12	2019-08-14	60,000	$29.34	$1.76M	98,970	SEC↗
Cole G Bradley	CFO	S Sale	2019-08-12	2019-08-14	58,775	$73.30	$4.31M	40,195	SEC↗
Cole G Bradley	CFO	S Sale	2019-08-12	2019-08-14	1,225	$73.75	$90.3K	38,970	SEC↗
Popovits Kimberly J	President and CEO	M Exercise deriv	2019-08-09	2019-08-12	25,000	—	$0	40,000	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-08-09	2019-08-12	24,000	$73.63	$1.77M	109,468	SEC↗
Popovits Kimberly J	President and CEO	M Exercise	2019-08-09	2019-08-12	25,000	$29.34	$733.5K	133,468	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-08-09	2019-08-12	1,000	$74.37	$74.4K	108,468	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise deriv	2019-08-08	2019-08-12	3,000	—	$0	3,000	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise deriv	2019-08-08	2019-08-12	1,103	—	$0	45,707	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise deriv	2019-08-08	2019-08-12	397	—	$0	6,000	SEC↗
Popovits Kimberly J	President and CEO	M Exercise deriv	2019-08-08	2019-08-12	25,000	—	$0	65,000	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-08-08	2019-08-12	700	$73.57	$51.5K	19,820	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise	2019-08-08	2019-08-12	397	$31.12	$12.4K	16,814	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-08-08	2019-08-12	1,277	$74.21	$94.8K	16,417	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-08-08	2019-08-12	1,723	$73.56	$126.7K	17,694	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-08-08	2019-08-12	403	$74.20	$29.9K	19,417	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-08-08	2019-08-12	397	$72.80	$28.9K	20,520	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise	2019-08-08	2019-08-12	3,000	$31.12	$93.4K	20,917	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise	2019-08-08	2019-08-12	1,103	$33.21	$36.6K	17,917	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-08-08	2019-08-12	9,235	$74.23	$685.5K	108,468	SEC↗
Popovits Kimberly J	President and CEO	S Sale	2019-08-08	2019-08-12	15,765	$73.63	$1.16M	117,703	SEC↗
Popovits Kimberly J	President and CEO	M Exercise	2019-08-08	2019-08-12	25,000	$29.34	$733.5K	133,468	SEC↗
Cole G Bradley	CFO	G Gift	2019-08-07	2019-08-14	5,000	—	$0	38,970	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-08-06	2019-08-07	16,860	$72.14	$1.22M	91,935	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-08-06	2019-08-07	8,140	$72.86	$593.1K	83,795	SEC↗
McEachron Kim	Chief People Officer	M Exercise deriv	2019-08-05	2019-08-07	2,438	—	$0	6,562	SEC↗
McEachron Kim	Chief People Officer	M Exercise deriv	2019-08-05	2019-08-07	9,665	—	$0	0	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-08-05	2019-08-07	2,471	$71.85	$177.5K	108,795	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-08-05	2019-08-07	22,529	$71.22	$1.60M	111,266	SEC↗
McEachron Kim	Chief People Officer	S Sale	2019-08-05	2019-08-07	12,103	$71.53	$865.7K	36,472	SEC↗
McEachron Kim	Chief People Officer	M Exercise	2019-08-05	2019-08-07	2,438	$28.05	$68.4K	48,575	SEC↗
McEachron Kim	Chief People Officer	M Exercise	2019-08-05	2019-08-07	9,665	$30.69	$296.6K	46,137	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-08-02	2019-08-05	25,000	$72.43	$1.81M	133,795	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-08-01	2019-08-05	17,628	$72.72	$1.28M	166,167	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-08-01	2019-08-05	7,372	$73.22	$539.8K	158,795	SEC↗
Cole G Bradley	CFO	M Exercise deriv	2019-07-09	2019-07-11	6,471	—	$0	0	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-07-09	2019-07-10	7,800	$57.06	$445.1K	183,795	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-07-09	2019-07-10	17,200	$56.27	$967.8K	191,595	SEC↗
Cole G Bradley	CFO	S Sale	2019-07-09	2019-07-11	1,438	$56.23	$80.9K	49,003	SEC↗
Cole G Bradley	CFO	M Exercise	2019-07-09	2019-07-11	6,471	$17.18	$111.2K	50,441	SEC↗
Cole G Bradley	CFO	S Sale	2019-07-09	2019-07-11	5,033	$57.33	$288.5K	43,970	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise deriv	2019-07-08	2019-07-09	3,000	—	$0	6,397	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise deriv	2019-07-08	2019-07-09	1,500	—	$0	9,397	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise	2019-07-08	2019-07-09	1,500	$31.12	$46.7K	20,917	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise	2019-07-08	2019-07-09	3,000	$31.12	$93.4K	19,417	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-07-08	2019-07-09	501	$57.85	$29.0K	17,917	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-07-08	2019-07-09	2,499	$56.95	$142.3K	18,418	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-07-08	2019-07-09	1,300	$56.95	$74.0K	16,617	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-07-08	2019-07-09	200	$57.74	$11.5K	16,417	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-07-08	2019-07-10	4,048	$57.76	$233.8K	208,795	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-07-08	2019-07-10	20,952	$56.97	$1.19M	212,843	SEC↗
McEachron Kim	Chief People Officer	M Exercise deriv	2019-07-05	2019-07-09	5,335	—	$0	9,665	SEC↗
McEachron Kim	Chief People Officer	M Exercise	2019-07-05	2019-07-09	5,335	$30.69	$163.7K	41,807	SEC↗
McEachron Kim	Chief People Officer	S Sale	2019-07-05	2019-07-09	5,335	$60.01	$320.2K	36,472	SEC↗
Baker Bros. Investments II, L.	Director, 10% Owner	A Award	2019-07-01	2019-07-03	424	$58.86	$25.0K	1,216,909	SEC↗
Baker Bros. Investments II, L.	Director, 10% Owner	A Award	2019-07-01	2019-07-03	424	$58.86	$25.0K	244,225	SEC↗
Baker Bros. Investments II, L.	Director, 10% Owner	A Award	2019-07-01	2019-07-03	424	$58.86	$25.0K	159,853	SEC↗
Baker Bros. Investments II, L.	Director, 10% Owner	A Award	2019-07-01	2019-07-03	424	$58.86	$25.0K	7,641,672	SEC↗
Baker Bros. Investments II, L.	Director, 10% Owner	A Award	2019-07-01	2019-07-03	424	$58.86	$25.0K	173,425	SEC↗
Baker Bros. Investments II, L.	Director, 10% Owner	A Award	2019-07-01	2019-07-03	424	$58.86	$25.0K	52,227	SEC↗
GRAHAM GINGER L	Director	A Award	2019-07-01	2019-07-03	212	$58.86	$12.5K	53,119	SEC↗
FUCHS HENRY J	Director	A Award	2019-07-01	2019-07-03	212	$58.86	$12.5K	7,648	SEC↗
Flannelly Barry P	Director	A Award	2019-07-01	2019-07-03	212	$58.86	$12.5K	212	SEC↗
Cohen Fred E	Director	A Award	2019-07-01	2019-07-03	212	$58.86	$12.5K	68,935	SEC↗
Shak Steven	Chief Scientific Officer	M Exercise deriv	2019-06-14	2019-06-17	10,550	—	$0	0	SEC↗
14159, L.P.	Director, 10% Owner	A Award deriv	2019-06-14	2019-06-18	13,166	—	$0	13,166	SEC↗
Parker Geoffrey M.	Director	A Award deriv	2019-06-14	2019-06-18	6,583	—	$0	6,583	SEC↗
GRAHAM GINGER L	Director	A Award deriv	2019-06-14	2019-06-18	6,583	—	$0	6,583	SEC↗
FUCHS HENRY J	Director	A Award deriv	2019-06-14	2019-06-18	6,583	—	$0	6,583	SEC↗
Cohen Fred E	Director	A Award deriv	2019-06-14	2019-06-18	6,583	—	$0	6,583	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-06-14	2019-06-17	1,664	$52.27	$87.0K	233,795	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-06-14	2019-06-17	8,886	$51.54	$458.0K	235,459	SEC↗
Shak Steven	Chief Scientific Officer	M Exercise	2019-06-14	2019-06-17	10,550	$31.12	$328.3K	244,345	SEC↗
14159, L.P.	Director, 10% Owner	A Award	2019-06-14	2019-06-18	1,910	—	$0	51,803	SEC↗
14159, L.P.	Director, 10% Owner	A Award	2019-06-14	2019-06-18	1,910	—	$0	173,001	SEC↗
14159, L.P.	Director, 10% Owner	A Award	2019-06-14	2019-06-18	1,910	—	$0	7,641,248	SEC↗
14159, L.P.	Director, 10% Owner	A Award	2019-06-14	2019-06-18	1,910	—	$0	1,216,485	SEC↗
14159, L.P.	Director, 10% Owner	A Award	2019-06-14	2019-06-18	1,910	—	$0	243,801	SEC↗
14159, L.P.	Director, 10% Owner	A Award	2019-06-14	2019-06-18	1,910	—	$0	159,429	SEC↗
Parker Geoffrey M.	Director	A Award	2019-06-14	2019-06-18	955	—	$0	955	SEC↗
GRAHAM GINGER L	Director	A Award	2019-06-14	2019-06-18	955	—	$0	52,907	SEC↗
FUCHS HENRY J	Director	A Award	2019-06-14	2019-06-18	955	—	$0	7,436	SEC↗
Cohen Fred E	Director	A Award	2019-06-14	2019-06-18	955	—	$0	68,723	SEC↗
Shak Steven	Chief Scientific Officer	M Exercise deriv	2019-06-13	2019-06-17	25,000	—	$0	10,550	SEC↗
Shak Steven	Chief Scientific Officer	M Exercise	2019-06-13	2019-06-17	25,000	$31.12	$778.0K	258,795	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-06-13	2019-06-17	809	$52.43	$42.4K	233,795	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-06-13	2019-06-17	24,191	$51.93	$1.26M	234,604	SEC↗
Shak Steven	Chief Scientific Officer	M Exercise deriv	2019-06-12	2019-06-13	9,887	—	$0	35,550	SEC↗
Shak Steven	Chief Scientific Officer	M Exercise deriv	2019-06-12	2019-06-13	15,113	—	$0	0	SEC↗
Shak Steven	Chief Scientific Officer	M Exercise	2019-06-12	2019-06-13	15,113	$30.84	$466.1K	248,592	SEC↗
Shak Steven	Chief Scientific Officer	M Exercise	2019-06-12	2019-06-13	9,887	$31.12	$307.7K	258,479	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-06-12	2019-06-13	25,000	$51.34	$1.28M	233,479	SEC↗
Cole G Bradley	CFO	M Exercise deriv	2019-06-11	2019-06-13	5,000	—	$0	6,471	SEC↗
Shak Steven	Chief Scientific Officer	M Exercise deriv	2019-06-11	2019-06-13	4,563	—	$0	45,437	SEC↗
Shak Steven	Chief Scientific Officer	M Exercise deriv	2019-06-11	2019-06-13	20,437	—	$0	15,113	SEC↗
Cole G Bradley	CFO	S Sale	2019-06-11	2019-06-13	4,230	$51.30	$217.0K	44,492	SEC↗
Cole G Bradley	CFO	S Sale	2019-06-11	2019-06-13	770	$52.34	$40.3K	43,722	SEC↗
Cole G Bradley	CFO	M Exercise	2019-06-11	2019-06-13	5,000	$17.18	$85.9K	48,722	SEC↗
Shak Steven	Chief Scientific Officer	M Exercise	2019-06-11	2019-06-13	4,563	$31.12	$142.0K	238,042	SEC↗
Shak Steven	Chief Scientific Officer	M Exercise	2019-06-11	2019-06-13	20,437	$30.84	$630.3K	258,479	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-06-11	2019-06-13	21,298	$51.27	$1.09M	237,181	SEC↗
Shak Steven	Chief Scientific Officer	S Sale	2019-06-11	2019-06-13	3,702	$52.33	$193.7K	233,479	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise deriv	2019-06-06	2019-06-10	1,500	—	$0	10,897	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise deriv	2019-06-06	2019-06-10	3,000	—	$0	12,397	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-06-06	2019-06-10	1,400	$52.30	$73.2K	20,520	SEC↗
Vaughn James J	Chief Commercial Officer	M Exercise	2019-06-06	2019-06-10	3,000	$31.12	$93.4K	23,420	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-06-06	2019-06-10	271	$54.65	$14.8K	16,175	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-06-06	2019-06-10	370	$53.06	$19.6K	16,446	SEC↗
Vaughn James J	Chief Commercial Officer	S Sale	2019-06-06	2019-06-10	3,604	$52.25	$188.3K	16,816	SEC↗