Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
$78.39M
10 trades · 4 insiders
Net · 90d
$-78.39M
Insiders on file
37
Daily buy vs sell · 90 days
■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Hudson Paul | Director | 1 | $0 | $0 | 2026-10-19 |
| Koppikar Utpal | Director | 1 | $0 | $0 | 2026-10-19 |
| Brennan David R | Director | 21 | $301.5K | $6.20M | 2026-09-09 |
| SHAROKY MELVIN MD | Director | 97 | $2.64M | $11.79M | 2026-08-17 |
| Adsett Roger | Chief Operating Officer | 99 | $47.9K | $94.68M | 2026-08-10 |
| Flammer Martina M.D. | Chief Medical Officer | 196 | $0 | $90.19M | 2026-08-06 |
| Lewis William | President and CEO | 486 | $1.31M | $121.53M | 2026-07-23 |
| Butera Samuele | SVP, GM, Global Respiratory | 2 | $0 | $0 | 2026-06-23 |
| Smith Michael Alexander | General Counsel, Senior VP | 108 | $0 | $33.12M | 2026-06-22 |
| Bonstein Sara | Chief Financial Officer | 115 | $0 | $44.19M | 2026-06-03 |
| Desjardins Clarissa | Director | 10 | $201.7K | $0 | 2026-05-13 |
| ANDERSON ELIZABETH M | Director | 11 | $0 | $2.98M | 2026-05-13 |
| LEE LEO | Director | 15 | $796.0K | $14.69M | 2026-05-13 |
| SCHAFER CAROL | Director | 8 | $0 | $0 | 2026-05-13 |
| MCGIRR DAVID W J | Director | 19 | $0 | $451.5K | 2026-02-09 |
| Schaeffer Orlov S Nicole | SVP, HR & Corp. Svcs. | 158 | $0 | $69.85M | 2026-01-02 |
| Wise John Drayton | Chief Commercial Officer | 39 | $0 | $3.03M | 2025-02-07 |
| ALTOMARI ALFRED | Director | 21 | $0 | $1.37M | 2024-05-13 |
| ENGELSEN STEINAR J | Director | 25 | $783.0K | $0 | 2021-11-01 |
| SORIANO JOHN | Chief Compliance Officer | 32 | $0 | $4.85M | 2021-09-07 |
| Pellizzari Christine A | General Counsel & Secretary | 89 | $407.5K | $7.94M | 2021-05-15 |
| GOLL JOHN | Chief Accounting Officer | 6 | $0 | $501.0K | 2020-01-03 |
| HAYDEN DONALD J JR | Director | 36 | $0 | $3.05M | 2019-04-09 |
| TOMBESI PAOLO | Chief Financial Officer | 4 | $0 | $0 | 2019-01-03 |
| STRECK PAUL | Chief Medical Officer | 4 | $0 | $0 | 2018-08-08 |
| POTTER MYRTLE S | Director | 9 | $0 | $82.7K | 2018-05-15 |
| SULLIVAN EUGENE JEFFREY | Chief Medical Officer | 6 | $0 | $0 | 2017-05-17 |
| Drechsler Andrew T | Chief Financial Officer | 22 | $0 | $990.4K | 2017-03-01 |
| Quigley Mark | Vice President, Quality | 8 | $0 | $413.8K | 2015-05-12 |
| WHITCOMB RANDALL W | Director | 14 | $0 | $0 | 2015-03-10 |
| Berry Peggy | Vice President, Regulatory | 5 | $0 | $0 | 2015-02-26 |
| Pauls Matthew | Chief Commercial Officer | 5 | $0 | $0 | 2014-06-02 |
| GUPTA RENU | Executive Vice President & CMO | 11 | $0 | $0 | 2014-01-31 |
| Kollender Richard S | Director | 8 | $0 | $0 | 2013-10-31 |
| FMR LLC | 10% Owner | 42 | $0 | $17.48M | 2013-07-22 |
| Drucker Andrea Holtzman | SVP, Gen. Counsel & Corp Sec. | 2 | $0 | $0 | 2013-06-03 |
| Whitten Timothy | President & CEO | 1 | $21.8K | $0 | 2012-06-01 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Koppikar Utpal | Director | A Award | 2026-10-19 | 2026-10-20 | 6,139 | — | — | 6,139 | SEC↗ |
| Hudson Paul | Director | A Award | 2026-10-19 | 2026-10-20 | 6,139 | — | — | 6,139 | SEC↗ |
| Brennan David R | Director | S Sale | 2026-09-09 | 2026-09-11 | 25,000 | $124.00 | $3.10M | 39,238 | SEC↗ |
| Brennan David R | Director | S Sale | 2026-09-09 | 2026-09-11 | 25,000 | $124.00 | $3.10M | 39,238 | SEC↗ |
| SHAROKY MELVIN MD | Director | S Sale | 2026-08-17 | 2026-08-19 | 5,000 | $127.53 | $637.6K | 0 | SEC↗ |
| SHAROKY MELVIN MD | Director | S Sale | 2026-08-17 | 2026-08-19 | 5,000 | $127.53 | $637.6K | 0 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise deriv | 2026-08-10 | 2026-08-12 | 76,600 | — | $0 | 0 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise deriv | 2026-08-10 | 2026-08-12 | 80,970 | — | $0 | 0 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise deriv | 2026-08-10 | 2026-08-12 | 82,280 | — | $0 | 0 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise | 2026-08-10 | 2026-08-12 | 80,970 | $30.46 | $2.47M | 338,594 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise | 2026-08-10 | 2026-08-12 | 76,600 | $17.16 | $1.31M | 257,624 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise | 2026-08-10 | 2026-08-12 | 82,280 | $13.67 | $1.12M | 181,024 | SEC↗ |
| Adsett Roger | Chief Operating Officer | S Sale | 2026-08-10 | 2026-08-12 | 239,850 | $133.27 | $31.96M | 98,744 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise deriv | 2026-08-10 | 2026-08-12 | 80,970 | — | $0 | 0 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise deriv | 2026-08-10 | 2026-08-12 | 76,600 | — | $0 | 0 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise deriv | 2026-08-10 | 2026-08-12 | 82,280 | — | $0 | 0 | SEC↗ |
| Adsett Roger | Chief Operating Officer | S Sale | 2026-08-10 | 2026-08-12 | 239,850 | $133.27 | $31.96M | 98,744 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise | 2026-08-10 | 2026-08-12 | 80,970 | $30.46 | $2.47M | 338,594 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise | 2026-08-10 | 2026-08-12 | 76,600 | $17.16 | $1.31M | 257,624 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise | 2026-08-10 | 2026-08-12 | 82,280 | $13.67 | $1.12M | 181,024 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise deriv | 2026-08-06 | 2026-08-07 | 8,895 | — | $0 | 35,580 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise deriv | 2026-08-06 | 2026-08-07 | 18,278 | — | $0 | 36,555 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-08-06 | 2026-08-07 | 18,278 | $129.40 | $2.37M | 60,486 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-08-06 | 2026-08-07 | 8,895 | $127.00 | $1.13M | 78,764 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise | 2026-08-06 | 2026-08-07 | 18,278 | $18.95 | $346.4K | 78,764 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise | 2026-08-06 | 2026-08-07 | 8,895 | $25.83 | $229.8K | 87,659 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise deriv | 2026-08-06 | 2026-08-07 | 8,895 | — | $0 | 35,580 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise deriv | 2026-08-06 | 2026-08-07 | 18,278 | — | $0 | 36,555 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-08-06 | 2026-08-07 | 18,278 | $129.40 | $2.37M | 60,486 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-08-06 | 2026-08-07 | 8,895 | $127.00 | $1.13M | 78,764 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise | 2026-08-06 | 2026-08-07 | 8,895 | $25.83 | $229.8K | 87,659 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise | 2026-08-06 | 2026-08-07 | 18,278 | $18.95 | $346.4K | 78,764 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-07-23 | 2026-07-24 | 4,440 | — | $0 | 0 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-07-23 | 2026-07-24 | 6,260 | — | $0 | 0 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-07-23 | 2026-07-24 | 5,872 | $106.43 | $625.0K | 259,058 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-07-23 | 2026-07-24 | 4,828 | $105.62 | $509.9K | 264,930 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-07-23 | 2026-07-24 | 4,440 | $17.16 | $76.2K | 269,758 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-07-23 | 2026-07-24 | 6,260 | $30.46 | $190.7K | 265,318 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-07-09 | 2026-07-10 | 6,259 | — | $0 | 6,260 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-07-09 | 2026-07-10 | 4,440 | — | $0 | 4,440 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-07-09 | 2026-07-10 | 5,005 | $116.55 | $583.3K | 264,752 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-07-09 | 2026-07-10 | 3,359 | $118.52 | $398.1K | 259,058 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-07-09 | 2026-07-10 | 2,335 | $117.62 | $274.6K | 262,417 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-07-09 | 2026-07-10 | 6,259 | $30.46 | $190.6K | 265,317 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-07-09 | 2026-07-10 | 4,440 | $17.16 | $76.2K | 269,757 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise deriv | 2026-07-06 | 2026-07-08 | 4,357 | — | $0 | 4,358 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise deriv | 2026-07-06 | 2026-07-08 | 7,945 | — | $0 | 23,835 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-07-06 | 2026-07-08 | 4,854 | $109.02 | $529.2K | 67,934 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise | 2026-07-06 | 2026-07-08 | 4,357 | $19.74 | $86.0K | 72,788 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise | 2026-07-06 | 2026-07-08 | 7,945 | $29.13 | $231.4K | 68,431 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-07-06 | 2026-07-08 | 7,448 | $110.60 | $823.7K | 60,486 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-06-25 | 2026-06-26 | 8,880 | — | $0 | 8,880 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-06-25 | 2026-06-26 | 12,518 | — | $0 | 12,519 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-06-25 | 2026-06-26 | 12,518 | $30.46 | $381.3K | 271,435 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-06-25 | 2026-06-26 | 8,880 | $17.16 | $152.4K | 280,315 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-06-25 | 2026-06-26 | 12,091 | $102.34 | $1.24M | 268,224 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-06-25 | 2026-06-26 | 1,836 | $103.10 | $189.3K | 266,388 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-06-25 | 2026-06-26 | 3,723 | $104.28 | $388.2K | 262,665 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-06-25 | 2026-06-26 | 2,456 | $105.27 | $258.5K | 260,209 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-06-25 | 2026-06-26 | 1,292 | $106.27 | $137.3K | 258,917 | SEC↗ |
| Butera Samuele | SVP, GM, Global Respiratory | A Award deriv | 2026-06-23 | 2026-06-24 | 12,570 | — | $0 | 12,570 | SEC↗ |
| Butera Samuele | SVP, GM, Global Respiratory | A Award | 2026-06-23 | 2026-06-24 | 7,342 | — | $0 | 7,342 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | S Sale | 2026-06-22 | 2026-06-24 | 1,806 | $95.82 | $173.1K | 37,648 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-06-08 | 2026-06-10 | 6,515 | $94.03 | $612.6K | 258,917 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-06-05 | 2026-06-05 | 1,858 | $103.78 | $192.8K | 60,486 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-06-03 | 2026-06-05 | 2,566 | $102.27 | $262.4K | 62,344 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-06-03 | 2026-06-05 | 7,605 | $102.27 | $777.8K | 265,432 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | S Sale | 2026-06-03 | 2026-06-05 | 2,159 | $102.27 | $220.8K | 39,454 | SEC↗ |
| Bonstein Sara | Chief Financial Officer | S Sale | 2026-06-03 | 2026-06-05 | 2,404 | $102.27 | $245.9K | 69,082 | SEC↗ |
| Adsett Roger | Chief Operating Officer | S Sale | 2026-06-03 | 2026-06-05 | 2,370 | $102.27 | $242.4K | 98,603 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | S Sale | 2026-05-22 | 2026-05-22 | 6,149 | $108.47 | $667.0K | 41,613 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-05-18 | 2026-05-20 | 4,440 | — | $0 | 17,760 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-05-18 | 2026-05-20 | 6,259 | — | $0 | 25,037 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-05-18 | 2026-05-20 | 11,836 | $106.39 | $1.26M | 281,012 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-05-18 | 2026-05-20 | 6,259 | $30.46 | $190.6K | 294,161 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-05-18 | 2026-05-20 | 4,440 | $17.16 | $76.2K | 298,601 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-05-18 | 2026-05-20 | 5,753 | $105.32 | $605.9K | 292,848 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-05-18 | 2026-05-20 | 7,975 | $106.97 | $853.1K | 273,037 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-05-14 | 2026-05-15 | 10,479 | $117.54 | $1.23M | 64,910 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-05-13 | 2026-05-15 | 13,283 | $116.18 | $1.54M | 287,902 | SEC↗ |
| LEE LEO | Director | A Award | 2026-05-13 | 2026-05-15 | 3,305 | — | $0 | 57,971 | SEC↗ |
| Desjardins Clarissa | Director | A Award | 2026-05-13 | 2026-05-15 | 3,305 | — | $0 | 70,312 | SEC↗ |
| Brennan David R | Director | A Award | 2026-05-13 | 2026-05-15 | 3,305 | — | $0 | 64,238 | SEC↗ |
| SHAROKY MELVIN MD | Director | A Award | 2026-05-13 | 2026-05-15 | 3,305 | — | $0 | 246,081 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | S Sale | 2026-05-13 | 2026-05-15 | 4,109 | $116.18 | $477.4K | 47,762 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-05-13 | 2026-05-15 | 3,384 | $116.18 | $393.2K | 75,389 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-05-13 | 2026-05-15 | 4,470 | $112.76 | $504.0K | 78,773 | SEC↗ |
| ANDERSON ELIZABETH M | Director | A Award | 2026-05-13 | 2026-05-15 | 3,305 | — | $0 | 62,034 | SEC↗ |
| Adsett Roger | Chief Operating Officer | S Sale | 2026-05-13 | 2026-05-15 | 5,837 | $116.18 | $678.1K | 100,973 | SEC↗ |
| SCHAFER CAROL | Director | A Award | 2026-05-13 | 2026-05-15 | 3,305 | — | $0 | 66,622 | SEC↗ |
| Bonstein Sara | Chief Financial Officer | S Sale | 2026-05-13 | 2026-05-15 | 8,272 | $116.18 | $961.0K | 71,486 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise deriv | 2026-05-11 | 2026-05-13 | 12,949 | — | $0 | 0 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-05-11 | 2026-05-13 | 830 | $101.18 | $84.0K | 83,243 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-05-11 | 2026-05-13 | 12,119 | $100.35 | $1.22M | 84,073 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise | 2026-05-11 | 2026-05-13 | 12,949 | $17.07 | $221.0K | 96,192 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-05-04 | 2026-05-06 | 6,259 | — | $0 | 31,296 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-05-04 | 2026-05-06 | 4,440 | — | $0 | 22,200 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-05-04 | 2026-05-06 | 599 | $135.18 | $81.0K | 310,852 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-05-04 | 2026-05-06 | 1,247 | $139.09 | $173.4K | 301,566 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-05-04 | 2026-05-06 | 2,721 | $137.86 | $375.1K | 302,813 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-05-04 | 2026-05-06 | 5,318 | $137.01 | $728.6K | 305,534 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-05-04 | 2026-05-06 | 381 | $139.60 | $53.2K | 301,185 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-05-04 | 2026-05-06 | 433 | $134.18 | $58.1K | 311,451 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-05-04 | 2026-05-06 | 4,440 | $17.16 | $76.2K | 311,884 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-05-04 | 2026-05-06 | 6,259 | $30.46 | $190.6K | 307,444 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-04-16 | 2026-04-17 | 4,440 | — | $0 | 26,640 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-04-16 | 2026-04-17 | 6,259 | — | $0 | 37,555 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-04-16 | 2026-04-17 | 825 | $145.79 | $120.3K | 301,185 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-04-16 | 2026-04-17 | 2,255 | $144.66 | $326.2K | 302,010 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-04-16 | 2026-04-17 | 5,373 | $143.81 | $772.7K | 304,265 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-04-16 | 2026-04-17 | 2,246 | $142.99 | $321.2K | 309,638 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-04-16 | 2026-04-17 | 4,440 | $17.16 | $76.2K | 311,884 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-04-16 | 2026-04-17 | 6,259 | $30.46 | $190.6K | 307,444 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-04-06 | 2026-04-08 | 4,440 | — | $0 | 31,080 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-04-06 | 2026-04-08 | 6,259 | — | $0 | 43,814 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-04-06 | 2026-04-08 | 1,434 | $164.01 | $235.2K | 301,185 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-04-06 | 2026-04-08 | 6,259 | $30.46 | $190.6K | 307,444 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-04-06 | 2026-04-08 | 4,440 | $17.16 | $76.2K | 311,884 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-04-06 | 2026-04-08 | 787 | $161.73 | $127.3K | 311,097 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-04-06 | 2026-04-08 | 8,478 | $163.23 | $1.38M | 302,619 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise deriv | 2026-04-01 | 2026-04-03 | 88,060 | — | $0 | 0 | SEC↗ |
| Adsett Roger | Chief Operating Officer | S Sale | 2026-04-01 | 2026-04-03 | 19,001 | $164.11 | $3.12M | 169,154 | SEC↗ |
| Adsett Roger | Chief Operating Officer | S Sale | 2026-04-01 | 2026-04-03 | 62,344 | $164.95 | $10.28M | 106,810 | SEC↗ |
| Adsett Roger | Chief Operating Officer | S Sale | 2026-04-01 | 2026-04-03 | 6,715 | $163.18 | $1.10M | 188,155 | SEC↗ |
| Adsett Roger | Chief Operating Officer | M Exercise | 2026-04-01 | 2026-04-03 | 88,060 | $14.56 | $1.28M | 194,870 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | M Exercise deriv | 2026-03-30 | 2026-03-31 | 5,649 | — | $0 | 8,633 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | M Exercise deriv | 2026-03-30 | 2026-03-31 | 13,989 | — | $0 | 18,561 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | S Sale | 2026-03-30 | 2026-03-31 | 19,638 | $150.98 | $2.96M | 51,871 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | M Exercise | 2026-03-30 | 2026-03-31 | 5,649 | $17.07 | $96.4K | 57,520 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | M Exercise | 2026-03-30 | 2026-03-31 | 13,989 | $27.89 | $390.2K | 71,509 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-03-19 | 2026-03-20 | 4,440 | — | $0 | 35,520 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-03-19 | 2026-03-20 | 6,259 | — | $0 | 50,073 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-03-19 | 2026-03-20 | 4,533 | $144.11 | $653.3K | 301,185 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-03-19 | 2026-03-20 | 4,537 | $143.42 | $650.7K | 305,718 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-03-19 | 2026-03-20 | 1,629 | $142.17 | $231.6K | 310,255 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-03-19 | 2026-03-20 | 6,259 | $30.46 | $190.6K | 307,444 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-03-19 | 2026-03-20 | 4,440 | $17.16 | $76.2K | 311,884 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-03-05 | 2026-03-05 | 6,259 | — | $0 | 56,332 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-03-05 | 2026-03-05 | 4,440 | — | $0 | 39,960 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-03-05 | 2026-03-05 | 3,899 | $146.66 | $571.8K | 303,313 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-03-05 | 2026-03-05 | 2,589 | $145.27 | $376.1K | 307,212 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-03-05 | 2026-03-05 | 2,083 | $144.23 | $300.4K | 309,801 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-03-05 | 2026-03-05 | 4,440 | $17.16 | $76.2K | 311,884 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-03-05 | 2026-03-05 | 6,259 | $30.46 | $190.6K | 307,444 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-03-05 | 2026-03-05 | 2,128 | $147.54 | $314.0K | 301,185 | SEC↗ |
| SHAROKY MELVIN MD | Director | G Gift | 2026-03-03 | 2026-03-05 | 100 | — | $0 | 242,776 | SEC↗ |
| SHAROKY MELVIN MD | Director | G Gift | 2026-02-25 | 2026-02-27 | 1,072 | — | $0 | 242,876 | SEC↗ |
| SHAROKY MELVIN MD | Director | G Gift | 2026-02-25 | 2026-02-27 | 243 | — | $0 | 5,423 | SEC↗ |
| SHAROKY MELVIN MD | Director | G Gift | 2026-02-25 | 2026-02-27 | 243 | — | $0 | 3,724 | SEC↗ |
| SHAROKY MELVIN MD | Director | G Gift | 2026-02-25 | 2026-02-27 | 243 | — | $0 | 5,007 | SEC↗ |
| SHAROKY MELVIN MD | Director | G Gift | 2026-02-25 | 2026-02-27 | 243 | — | $0 | 819 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | M Exercise deriv | 2026-02-24 | 2026-02-25 | 20,248 | — | $0 | 14,282 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | S Sale | 2026-02-24 | 2026-02-25 | 15,771 | $156.53 | $2.47M | 51,871 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | S Sale | 2026-02-24 | 2026-02-25 | 4,151 | $155.06 | $643.7K | 67,642 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | S Sale | 2026-02-24 | 2026-02-25 | 4,852 | $153.93 | $746.9K | 71,793 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | M Exercise | 2026-02-24 | 2026-02-25 | 20,248 | $17.07 | $345.6K | 76,645 | SEC↗ |
| Brennan David R | Director | G Gift | 2026-02-23 | 2026-02-25 | 6,000 | — | $0 | 60,933 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-02-19 | 2026-02-23 | 4,440 | — | $0 | 44,400 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-02-19 | 2026-02-23 | 6,259 | — | $0 | 62,591 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-02-19 | 2026-02-23 | 2,377 | $151.92 | $361.1K | 302,215 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-02-19 | 2026-02-23 | 6,259 | $30.46 | $190.6K | 307,444 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-02-19 | 2026-02-23 | 4,440 | $17.16 | $76.2K | 311,884 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-02-19 | 2026-02-23 | 1,988 | $149.17 | $296.5K | 309,896 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-02-19 | 2026-02-23 | 1,891 | $150.10 | $283.8K | 308,005 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-02-19 | 2026-02-23 | 3,413 | $151.12 | $515.8K | 304,592 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-02-19 | 2026-02-23 | 1,030 | $153.38 | $158.0K | 301,185 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-02-09 | 2026-02-11 | 4,440 | — | $0 | 48,840 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-02-09 | 2026-02-11 | 6,259 | — | $0 | 68,850 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-02-09 | 2026-02-11 | 7,221 | $148.02 | $1.07M | 302,472 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-02-09 | 2026-02-11 | 4,440 | $17.16 | $76.2K | 308,322 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-02-09 | 2026-02-11 | 6,259 | $30.46 | $190.6K | 314,581 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-02-09 | 2026-02-11 | 4,888 | $147.17 | $719.4K | 309,693 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-02-09 | 2026-02-11 | 1,287 | $148.83 | $191.5K | 301,185 | SEC↗ |
| MCGIRR DAVID W J | Director | G Gift | 2026-02-09 | 2026-02-11 | 53,400 | — | $0 | 53,400 | SEC↗ |
| MCGIRR DAVID W J | Director | G Gift | 2026-02-09 | 2026-02-11 | 53,400 | — | $0 | 44,323 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-02-05 | 2026-02-06 | 869 | $152.44 | $132.5K | 83,243 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-02-03 | 2026-02-04 | 795 | $155.77 | $123.8K | 84,112 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | S Sale | 2026-02-03 | 2026-02-04 | 640 | $156.27 | $100.0K | 56,397 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-02-03 | 2026-02-04 | 3,009 | $156.34 | $470.4K | 303,882 | SEC↗ |
| Bonstein Sara | Chief Financial Officer | S Sale | 2026-02-03 | 2026-02-04 | 748 | $156.34 | $116.9K | 79,758 | SEC↗ |
| Adsett Roger | Chief Operating Officer | S Sale | 2026-02-03 | 2026-02-04 | 791 | $156.17 | $123.5K | 106,810 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise deriv | 2026-02-02 | 2026-02-04 | 7,982 | — | $0 | 23,948 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise | 2026-02-02 | 2026-02-04 | 7,982 | $65.72 | $524.6K | 92,889 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-02-02 | 2026-02-04 | 563 | $152.06 | $85.6K | 92,326 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-02-02 | 2026-02-04 | 928 | $153.16 | $142.1K | 91,398 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-02-02 | 2026-02-04 | 3,349 | $154.56 | $517.6K | 88,049 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-02-02 | 2026-02-04 | 3,042 | $155.46 | $472.9K | 85,007 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-02-02 | 2026-02-04 | 100 | $156.86 | $15.7K | 84,907 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-01-20 | 2026-01-22 | 4,440 | — | $0 | 53,280 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-01-20 | 2026-01-22 | 6,259 | — | $0 | 75,109 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-20 | 2026-01-22 | 2,229 | $159.85 | $356.3K | 307,145 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-20 | 2026-01-22 | 5,967 | $158.99 | $948.7K | 309,374 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-20 | 2026-01-22 | 1,243 | $158.37 | $196.9K | 315,341 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-20 | 2026-01-22 | 254 | $160.70 | $40.8K | 306,891 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-01-20 | 2026-01-22 | 4,440 | $17.16 | $76.2K | 317,590 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-01-20 | 2026-01-22 | 6,259 | $30.46 | $190.6K | 313,150 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-20 | 2026-01-22 | 1,006 | $156.80 | $157.7K | 316,584 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-01-12 | 2026-01-13 | 4,440 | — | $0 | 57,720 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2026-01-12 | 2026-01-13 | 6,259 | — | $0 | 81,368 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-12 | 2026-01-13 | 160 | $170.24 | $27.2K | 307,800 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-01-12 | 2026-01-13 | 6,259 | $30.46 | $190.6K | 321,666 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2026-01-12 | 2026-01-13 | 4,440 | $17.16 | $76.2K | 326,106 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-12 | 2026-01-13 | 3,974 | $167.73 | $666.6K | 322,132 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-12 | 2026-01-13 | 315 | $174.86 | $55.1K | 306,891 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-12 | 2026-01-13 | 297 | $172.36 | $51.2K | 307,206 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-12 | 2026-01-13 | 297 | $171.31 | $50.9K | 307,503 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-12 | 2026-01-13 | 6,996 | $169.57 | $1.19M | 307,960 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-12 | 2026-01-13 | 7,176 | $168.63 | $1.21M | 314,956 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-09 | 2026-01-13 | 1,887 | $186.19 | $351.3K | 84,907 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | S Sale | 2026-01-08 | 2026-01-08 | 1,053 | $174.17 | $183.4K | 57,037 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-08 | 2026-01-08 | 3,223 | $174.17 | $561.3K | 315,407 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-08 | 2026-01-08 | 1,660 | $173.87 | $288.6K | 90,045 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-08 | 2026-01-08 | 3,251 | $174.17 | $566.2K | 86,794 | SEC↗ |
| Bonstein Sara | Chief Financial Officer | S Sale | 2026-01-08 | 2026-01-08 | 1,447 | $174.17 | $252.0K | 80,506 | SEC↗ |
| Adsett Roger | Chief Operating Officer | S Sale | 2026-01-08 | 2026-01-08 | 2,059 | $174.17 | $358.6K | 107,601 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | S Sale | 2026-01-07 | 2026-01-08 | 709 | $175.07 | $124.1K | 58,090 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-07 | 2026-01-08 | 2,357 | $175.07 | $412.6K | 318,630 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-07 | 2026-01-08 | 1,434 | $175.84 | $252.2K | 91,705 | SEC↗ |
| Bonstein Sara | Chief Financial Officer | S Sale | 2026-01-07 | 2026-01-08 | 1,678 | $175.07 | $293.8K | 81,953 | SEC↗ |
| Adsett Roger | Chief Operating Officer | S Sale | 2026-01-07 | 2026-01-08 | 802 | $175.07 | $140.4K | 109,660 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise deriv | 2026-01-06 | 2026-01-08 | 8,570 | — | $0 | 0 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | S Sale | 2026-01-06 | 2026-01-08 | 1,396 | $173.33 | $242.0K | 58,799 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2026-01-06 | 2026-01-08 | 4,096 | $173.33 | $710.0K | 320,987 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-06 | 2026-01-08 | 2,830 | $174.21 | $493.0K | 95,711 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-06 | 2026-01-08 | 957 | $175.01 | $167.5K | 94,754 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-06 | 2026-01-08 | 1,615 | $173.33 | $279.9K | 93,139 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-06 | 2026-01-08 | 4,783 | $173.47 | $829.7K | 98,541 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise | 2026-01-06 | 2026-01-08 | 8,570 | $26.43 | $226.5K | 103,324 | SEC↗ |
| Bonstein Sara | Chief Financial Officer | S Sale | 2026-01-06 | 2026-01-08 | 1,517 | $173.33 | $262.9K | 83,631 | SEC↗ |
| Adsett Roger | Chief Operating Officer | S Sale | 2026-01-06 | 2026-01-08 | 1,429 | $173.33 | $247.7K | 110,462 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise deriv | 2026-01-05 | 2026-01-06 | 7,945 | — | $0 | 31,780 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise deriv | 2026-01-05 | 2026-01-06 | 4,358 | — | $0 | 8,715 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-05 | 2026-01-06 | 655 | $174.28 | $114.2K | 95,456 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise | 2026-01-05 | 2026-01-06 | 4,358 | $19.74 | $86.0K | 99,112 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise | 2026-01-05 | 2026-01-06 | 7,945 | $29.13 | $231.4K | 107,057 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-05 | 2026-01-06 | 2,799 | $169.29 | $473.8K | 104,258 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-05 | 2026-01-06 | 702 | $175.73 | $123.4K | 94,754 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-05 | 2026-01-06 | 1,820 | $173.45 | $315.7K | 96,111 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-05 | 2026-01-06 | 286 | $171.92 | $49.2K | 97,931 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-05 | 2026-01-06 | 2,836 | $171.19 | $485.5K | 98,217 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2026-01-05 | 2026-01-06 | 3,205 | $170.61 | $546.8K | 101,053 | SEC↗ |
| Schaeffer Orlov S Nicole | Chief People Strategy Office | M Exercise deriv | 2026-01-02 | 2026-01-06 | 87,290 | — | $0 | 0 | SEC↗ |
| Schaeffer Orlov S Nicole | Chief People Strategy Office | A Award deriv | 2026-01-02 | 2026-01-06 | 27,600 | — | $0 | 27,600 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | A Award deriv | 2026-01-02 | 2026-01-06 | 27,600 | — | $0 | 27,600 | SEC↗ |
| Adsett Roger | Chief Operating Officer | A Award deriv | 2026-01-02 | 2026-01-06 | 31,280 | — | $0 | 31,280 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | A Award deriv | 2026-01-02 | 2026-01-06 | 31,280 | — | $0 | 31,280 | SEC↗ |
| Lewis William | Chair and CEO | A Award deriv | 2026-01-02 | 2026-01-06 | 110,400 | — | $0 | 110,400 | SEC↗ |
| Bonstein Sara | Chief Financial Officer | A Award deriv | 2026-01-02 | 2026-01-06 | 31,280 | — | $0 | 31,280 | SEC↗ |
| Schaeffer Orlov S Nicole | Chief People Strategy Office | S Sale | 2026-01-02 | 2026-01-06 | 34,103 | $175.17 | $5.97M | 63,911 | SEC↗ |
| Schaeffer Orlov S Nicole | Chief People Strategy Office | S Sale | 2026-01-02 | 2026-01-06 | 200 | $177.78 | $35.6K | 41,754 | SEC↗ |
| Schaeffer Orlov S Nicole | Chief People Strategy Office | S Sale | 2026-01-02 | 2026-01-06 | 9,125 | $177.17 | $1.62M | 41,954 | SEC↗ |
| Schaeffer Orlov S Nicole | Chief People Strategy Office | S Sale | 2026-01-02 | 2026-01-06 | 12,832 | $176.08 | $2.26M | 51,079 | SEC↗ |
| Schaeffer Orlov S Nicole | Chief People Strategy Office | S Sale | 2026-01-02 | 2026-01-06 | 31,030 | $174.28 | $5.41M | 98,014 | SEC↗ |
| Schaeffer Orlov S Nicole | Chief People Strategy Office | M Exercise | 2026-01-02 | 2026-01-06 | 87,290 | $13.91 | $1.21M | 129,044 | SEC↗ |
| Schaeffer Orlov S Nicole | Chief People Strategy Office | A Award | 2026-01-02 | 2026-01-06 | 5,293 | — | $0 | 41,754 | SEC↗ |
| Smith Michael Alexander | Chief Legal Officer | A Award | 2026-01-02 | 2026-01-06 | 5,293 | — | $0 | 60,195 | SEC↗ |
| Adsett Roger | Chief Operating Officer | A Award | 2026-01-02 | 2026-01-06 | 5,998 | — | $0 | 111,891 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | A Award | 2026-01-02 | 2026-01-06 | 5,998 | — | $0 | 89,109 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | A Award | 2026-01-02 | 2026-01-06 | 5,645 | — | $0 | 94,754 | SEC↗ |
| Lewis William | Chair and CEO | A Award | 2026-01-02 | 2026-01-06 | 21,172 | — | $0 | 325,083 | SEC↗ |
| Bonstein Sara | Chief Financial Officer | A Award | 2026-01-02 | 2026-01-06 | 5,998 | — | $0 | 79,503 | SEC↗ |
| Bonstein Sara | Chief Financial Officer | A Award | 2026-01-02 | 2026-01-06 | 5,645 | — | $0 | 85,148 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2025-12-18 | 2025-12-19 | 6,259 | — | $0 | 87,627 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2025-12-18 | 2025-12-19 | 4,440 | — | $0 | 62,160 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-18 | 2025-12-19 | 1,783 | $166.60 | $297.0K | 309,868 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2025-12-18 | 2025-12-19 | 4,440 | $17.16 | $76.2K | 308,351 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-18 | 2025-12-19 | 51 | $171.20 | $8.7K | 303,911 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-18 | 2025-12-19 | 362 | $170.26 | $61.6K | 303,962 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-18 | 2025-12-19 | 1,938 | $169.58 | $328.6K | 304,324 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-18 | 2025-12-19 | 2,175 | $168.54 | $366.6K | 306,262 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-18 | 2025-12-19 | 1,431 | $167.29 | $239.4K | 308,437 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-18 | 2025-12-19 | 697 | $165.21 | $115.2K | 311,651 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-18 | 2025-12-19 | 447 | $164.24 | $73.4K | 312,348 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-18 | 2025-12-19 | 1,465 | $163.19 | $239.1K | 312,795 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-18 | 2025-12-19 | 350 | $162.26 | $56.8K | 314,260 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2025-12-18 | 2025-12-19 | 6,259 | $30.46 | $190.6K | 314,610 | SEC↗ |
| SHAROKY MELVIN MD | Director | S Sale | 2025-12-05 | 2025-12-09 | 20,000 | $205.01 | $4.10M | 243,948 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2025-12-04 | 2025-12-05 | 4,440 | — | $0 | 66,600 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise deriv | 2025-12-04 | 2025-12-05 | 6,259 | — | $0 | 93,886 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-04 | 2025-12-05 | 2,222 | $205.66 | $457.0K | 307,872 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-04 | 2025-12-05 | 4,516 | $204.62 | $924.1K | 310,094 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2025-12-04 | 2025-12-05 | 4,440 | $17.16 | $76.2K | 314,610 | SEC↗ |
| Lewis William | Chair and CEO | M Exercise | 2025-12-04 | 2025-12-05 | 6,259 | $30.46 | $190.6K | 310,170 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-04 | 2025-12-05 | 1,040 | $207.42 | $215.7K | 303,911 | SEC↗ |
| Lewis William | Chair and CEO | S Sale | 2025-12-04 | 2025-12-05 | 2,921 | $206.49 | $603.2K | 304,951 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise deriv | 2025-12-01 | 2025-12-03 | 8,895 | — | $0 | 44,475 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | M Exercise | 2025-12-01 | 2025-12-03 | 8,895 | $25.83 | $229.8K | 92,006 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2025-12-01 | 2025-12-03 | 5,886 | $207.03 | $1.22M | 84,670 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2025-12-01 | 2025-12-03 | 1,559 | $207.73 | $323.9K | 83,111 | SEC↗ |
| Flammer Martina M.D. | Chief Medical Officer | S Sale | 2025-12-01 | 2025-12-03 | 1,450 | $205.98 | $298.7K | 90,556 | SEC↗ |
| ANDERSON ELIZABETH M | Director | S Sale | 2025-11-24 | 2025-11-26 | 5,000 | $204.58 | $1.02M | 58,729 | SEC↗ |
| LEE LEO | Director | S Sale | 2025-11-17 | 2025-11-18 | 3,212 | $193.51 | $621.6K | 126,465 | SEC↗ |
| LEE LEO | Director | S Sale | 2025-11-17 | 2025-11-18 | 24,076 | $196.61 | $4.73M | 69,851 | SEC↗ |
| LEE LEO | Director | S Sale | 2025-11-17 | 2025-11-18 | 17,594 | $194.49 | $3.42M | 108,871 | SEC↗ |
| LEE LEO | Director | S Sale | 2025-11-17 | 2025-11-18 | 14,944 | $195.39 | $2.92M | 93,927 | SEC↗ |
| LEE LEO | Director | S Sale | 2025-11-17 | 2025-11-18 | 15,174 | $197.40 | $3.00M | 54,677 | SEC↗ |
| ANDERSON ELIZABETH M | Director | S Sale | 2025-11-14 | 2025-11-18 | 10,000 | $195.87 | $1.96M | 63,729 | SEC↗ |
| Schaeffer Orlov S Nicole | Chief People Strategy Office | M Exercise deriv | 2025-11-12 | 2025-11-14 | 30,000 | — | $0 | 15,760 | SEC↗ |
| Schaeffer Orlov S Nicole | Chief People Strategy Office | S Sale | 2025-11-12 | 2025-11-14 | 19,183 | $194.44 | $3.73M | 36,625 | SEC↗ |
| Schaeffer Orlov S Nicole | Chief People Strategy Office | S Sale | 2025-11-12 | 2025-11-14 | 6,575 | $193.64 | $1.27M | 55,808 | SEC↗ |