Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$0
Insiders on file
37
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Winton Matthew | COO | 11 | $0 | $0 | 2025-07-01 |
| Subramanian Sanjay | SVP, CFO & Head of BD | 15 | $100.0K | $0 | 2025-07-01 |
| Sullivan Lynne Marie | Director | 6 | $0 | $0 | 2025-07-01 |
| Treco Douglas A | Director | 20 | $0 | $60.1K | 2025-07-01 |
| Bolte Axel | See Remarks | 21 | $250.0K | $0 | 2025-07-01 |
| Hopfner Robert Lorne | Director, 10% Owner | 18 | $16.20M | $0 | 2025-07-01 |
| Harris Erik | Director | 1 | $0 | $0 | 2024-10-03 |
| Bhagat Sarah M | Director | 5 | $0 | $0 | 2024-06-18 |
| Edwards Martin | Director | 5 | $0 | $0 | 2024-06-18 |
| Mathers Edward T | Director | 5 | $0 | $0 | 2024-06-18 |
| DIAZ REINALDO M | Director | 5 | $0 | $0 | 2024-06-18 |
| Pivotal bioVenture Partners Fund I, L.P. | Director | 2 | $4.00M | $0 | 2023-08-01 |
| Bjarke Henric Bjorn | See Remarks | 7 | $129.9K | $0 | 2022-12-15 |
| Pivotal bioVenture Partners Fund I U.G.P., Ltd | Director | 1 | $3.95M | $0 | 2022-04-19 |
| Longitude Capital Partners III, LLC | 10% Owner | 1 | $5.00M | $0 | 2022-04-19 |
| Inozyme Pharma, Inc. | Director | 1 | $0 | $0 | 2021-06-23 |
| DiPalma Stephen J. | Interim CFO | 1 | $0 | $0 | 2021-05-17 |
| Basso Stephen | Senior Vice President, Finance | 4 | $0 | $0 | 2021-03-24 |
| Jungles Steven J | See Remarks | 4 | $0 | $0 | 2021-03-04 |
| Wenkert Deborah | SVP, CMO | 1 | $0 | $0 | 2021-02-02 |
| Novo Holdings A/S | 10% Owner | 5 | $6.00M | $7.88M | 2021-01-28 |
| Huertas Pedro | See Remarks | 2 | $0 | $0 | 2021-01-13 |
| ALEXION PHARMACEUTICALS, INC. | 10% Owner | 2 | $0 | $0 | 2020-07-28 |
| Schlessinger Joseph | 10% Owner | 2 | $0 | $0 | 2020-07-28 |
| Pivotal bioVenture Partners Fund I G.P., L.P. | 10% Owner | 3 | $3.00M | $0 | 2020-07-28 |
| Rock Springs Capital LLC | 10% Owner | 4 | $9.60M | $0 | 2020-07-28 |
| Makhzoumi Mohamad | 10% Owner | 5 | $4.00M | $0 | 2020-07-28 |
| New Enterprise Associates 15, L.P. | 10% Owner | 5 | $4.00M | $0 | 2020-07-28 |
| Florence Anthony A. Jr. | 10% Owner | 5 | $4.00M | $0 | 2020-07-28 |
| Sonsini Peter W. | 10% Owner | 5 | $4.00M | $0 | 2020-07-28 |
| Tammenoms Bakker Juliet | 10% Owner | 5 | $10.00M | $0 | 2020-07-28 |
| Kolchinsky Peter | 10% Owner | 3 | $9.60M | $0 | 2020-07-28 |
| BASKETT FOREST | 10% Owner | 5 | $4.00M | $0 | 2020-07-28 |
| HEALY JAMES | 10% Owner | 3 | $7.00M | $0 | 2020-07-28 |
| SANDELL SCOTT D | 10% Owner | 5 | $4.00M | $0 | 2020-07-28 |
| MAKOWER JOSHUA | 10% Owner | 5 | $4.00M | $0 | 2020-07-28 |
| Sanofi | 10% Owner | 3 | $1.30M | $0 | 2020-07-28 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Treco Douglas A | CEO & Chairman | D To issuer deriv | 2025-07-01 | 2025-07-03 | 150,000 | — | $0 | 0 | SEC↗ |
| Treco Douglas A | CEO & Chairman | D To issuer deriv | 2025-07-01 | 2025-07-03 | 86,979 | — | $0 | 0 | SEC↗ |
| Treco Douglas A | CEO & Chairman | D To issuer deriv | 2025-07-01 | 2025-07-03 | 400,000 | — | $0 | 0 | SEC↗ |
| Sullivan Lynne Marie | Director | D To issuer deriv | 2025-07-01 | 2025-07-03 | 28,368 | — | $0 | 0 | SEC↗ |
| Bolte Axel | Director | D To issuer deriv | 2025-07-01 | 2025-07-03 | 234,176 | — | $0 | 0 | SEC↗ |
| Bolte Axel | Director | D To issuer deriv | 2025-07-01 | 2025-07-03 | 159,187 | — | $0 | 0 | SEC↗ |
| Winton Matthew | COO | D To issuer deriv | 2025-07-01 | 2025-07-03 | 145,000 | — | $0 | 0 | SEC↗ |
| Winton Matthew | COO | D To issuer deriv | 2025-07-01 | 2025-07-03 | 41,500 | — | $0 | 0 | SEC↗ |
| Subramanian Sanjay | SVP, CFO & Head of BD | D To issuer deriv | 2025-07-01 | 2025-07-03 | 38,500 | — | $0 | 0 | SEC↗ |
| Subramanian Sanjay | SVP, CFO & Head of BD | D To issuer deriv | 2025-07-01 | 2025-07-03 | 180,000 | — | $0 | 0 | SEC↗ |
| Subramanian Sanjay | SVP, CFO & Head of BD | D To issuer deriv | 2025-07-01 | 2025-07-03 | 135,000 | — | $0 | 0 | SEC↗ |
| Subramanian Sanjay | SVP, CFO & Head of BD | D To issuer deriv | 2025-07-01 | 2025-07-03 | 145,000 | — | $0 | 0 | SEC↗ |
| Hopfner Robert Lorne | Director | U Tender | 2025-07-01 | 2025-07-03 | 1,571,741 | $4.00 | $6.29M | 0 | SEC↗ |
| Hopfner Robert Lorne | Director | U Tender | 2025-07-01 | 2025-07-03 | 2,923,110 | $4.00 | $11.69M | 0 | SEC↗ |
| Treco Douglas A | CEO & Chairman | U Tender | 2025-07-01 | 2025-07-03 | 43,861 | $4.00 | $175.4K | 0 | SEC↗ |
| Bolte Axel | Director | U Tender | 2025-07-01 | 2025-07-03 | 423,926 | $4.00 | $1.70M | 0 | SEC↗ |
| Winton Matthew | COO | U Tender | 2025-07-01 | 2025-07-03 | 21,743 | $4.00 | $87.0K | 0 | SEC↗ |
| Subramanian Sanjay | SVP, CFO & Head of BD | U Tender | 2025-07-01 | 2025-07-03 | 39,701 | $4.00 | $158.8K | 0 | SEC↗ |
| Subramanian Sanjay | SVP, CFO & Head of BD | A Award | 2025-06-25 | 2025-06-27 | 6,813 | $0.74 | $5.0K | 39,701 | SEC↗ |
| Treco Douglas A | CEO & Chairman | A Award | 2025-06-25 | 2025-06-27 | 2,815 | $0.74 | $2.1K | 43,861 | SEC↗ |
| Winton Matthew | COO | A Award | 2025-06-25 | 2025-06-27 | 14,355 | $0.74 | $10.6K | 21,743 | SEC↗ |
| Bolte Axel | Director | M Exercise deriv | 2025-05-15 | 2025-05-20 | 152,823 | — | $0 | 0 | SEC↗ |
| Bolte Axel | Director | M Exercise deriv | 2025-05-15 | 2025-05-20 | 4,407 | — | $0 | 0 | SEC↗ |
| Bolte Axel | Director | M Exercise | 2025-05-15 | 2025-05-20 | 152,823 | $0.98 | $149.8K | 419,519 | SEC↗ |
| Bolte Axel | Director | M Exercise | 2025-05-15 | 2025-05-20 | 4,407 | $0.98 | $4.3K | 423,926 | SEC↗ |
| Treco Douglas A | CEO & Chairman | S Sale | 2025-04-02 | 2025-04-03 | 8,819 | $0.89 | $7.8K | 41,046 | SEC↗ |
| Treco Douglas A | CEO & Chairman | M Exercise deriv | 2025-04-01 | 2025-04-03 | 25,000 | — | $0 | 50,000 | SEC↗ |
| Treco Douglas A | CEO & Chairman | M Exercise | 2025-04-01 | 2025-04-03 | 25,000 | — | $0 | 49,865 | SEC↗ |
| Subramanian Sanjay | SVP, CFO & Head of BD | A Award | 2025-03-31 | 2025-04-02 | 2,490 | $0.77 | $1.9K | 32,888 | SEC↗ |
| Winton Matthew | COO | A Award | 2025-03-31 | 2025-04-02 | 2,490 | $0.77 | $1.9K | 7,388 | SEC↗ |
| Treco Douglas A | CEO | A Award deriv | 2025-03-11 | 2025-03-17 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Treco Douglas A | CEO | A Award deriv | 2025-03-11 | 2025-03-17 | 400,000 | — | $0 | 400,000 | SEC↗ |
| Winton Matthew | COO | A Award deriv | 2025-03-11 | 2025-03-17 | 145,000 | — | $0 | 145,000 | SEC↗ |
| Winton Matthew | COO | A Award deriv | 2025-03-11 | 2025-03-17 | 41,500 | — | $0 | 41,500 | SEC↗ |
| Subramanian Sanjay | SVP, CFO | A Award deriv | 2025-03-11 | 2025-03-17 | 38,500 | — | $0 | 38,500 | SEC↗ |
| Subramanian Sanjay | SVP, CFO | A Award deriv | 2025-03-11 | 2025-03-17 | 145,000 | — | $0 | 145,000 | SEC↗ |
| Harris Erik | Director | A Award deriv | 2024-10-03 | 2024-10-07 | 56,000 | — | $0 | 56,000 | SEC↗ |
| Winton Matthew | COO | A Award | 2024-09-30 | 2024-10-03 | 1,710 | $4.45 | $7.6K | 4,898 | SEC↗ |
| Treco Douglas A | CEO | A Award | 2024-09-30 | 2024-10-03 | 1,710 | $4.45 | $7.6K | 22,375 | SEC↗ |
| Edwards Martin | Director | A Award deriv | 2024-06-18 | 2024-06-20 | 28,000 | — | $0 | 28,000 | SEC↗ |
| Bolte Axel | Director | A Award deriv | 2024-06-18 | 2024-06-20 | 28,000 | — | $0 | 28,000 | SEC↗ |
| Bhagat Sarah M | Director | A Award deriv | 2024-06-18 | 2024-06-20 | 28,000 | — | $0 | 28,000 | SEC↗ |
| Sullivan Lynne Marie | Director | A Award deriv | 2024-06-18 | 2024-06-20 | 28,000 | — | $0 | 28,000 | SEC↗ |
| DIAZ REINALDO M | Director | A Award deriv | 2024-06-18 | 2024-06-20 | 28,000 | — | $0 | 28,000 | SEC↗ |
| Hopfner Robert Lorne | Director | A Award deriv | 2024-06-18 | 2024-06-20 | 28,000 | — | $0 | 28,000 | SEC↗ |
| Mathers Edward T | Director | A Award deriv | 2024-06-18 | 2024-06-20 | 28,000 | — | $0 | 28,000 | SEC↗ |
| Treco Douglas A | CEO | S Sale | 2024-04-02 | 2024-04-03 | 7,523 | $6.94 | $52.2K | 20,665 | SEC↗ |
| Treco Douglas A | CEO | M Exercise deriv | 2024-04-01 | 2024-04-03 | 25,000 | — | $0 | 75,000 | SEC↗ |
| Treco Douglas A | CEO | M Exercise | 2024-04-01 | 2024-04-03 | 25,000 | — | $0 | 28,188 | SEC↗ |
| Winton Matthew | COO | A Award | 2024-03-28 | 2024-04-03 | 3,188 | $3.33 | $10.6K | 3,188 | SEC↗ |
| Subramanian Sanjay | SVP, CFO | A Award deriv | 2024-03-13 | 2024-03-15 | 165,000 | — | $0 | 165,000 | SEC↗ |
| Treco Douglas A | CEO | A Award deriv | 2024-03-13 | 2024-03-15 | 300,000 | — | $0 | 300,000 | SEC↗ |
| Winton Matthew | COO | A Award deriv | 2024-03-13 | 2024-03-15 | 175,000 | — | $0 | 175,000 | SEC↗ |
| Subramanian Sanjay | SVP, CFO | A Award | 2023-09-29 | 2023-10-03 | 2,319 | $3.57 | $8.3K | 30,398 | SEC↗ |
| Hopfner Robert Lorne | Director | P Buy | 2023-08-01 | 2023-08-03 | 714,285 | $4.80 | $3.43M | 1,571,741 | SEC↗ |
| Hopfner Robert Lorne | Director | P Buy | 2023-08-01 | 2023-08-03 | 119,048 | $4.80 | $571.4K | 2,923,110 | SEC↗ |
| Pivotal bioVenture Partners Fu | Director | P Buy | 2023-08-01 | 2023-08-03 | 119,048 | $4.80 | $571.4K | 2,923,110 | SEC↗ |
| Pivotal bioVenture Partners Fu | Director | P Buy | 2023-08-01 | 2023-08-03 | 714,285 | $4.80 | $3.43M | 1,571,741 | SEC↗ |
| Bhagat Sarah M | Director | A Award deriv | 2023-06-13 | 2023-06-15 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Bolte Axel | Director | A Award deriv | 2023-06-13 | 2023-06-15 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Hopfner Robert Lorne | Director | A Award deriv | 2023-06-13 | 2023-06-15 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Edwards Martin | Director | A Award deriv | 2023-06-13 | 2023-06-15 | 16,000 | — | $0 | 16,000 | SEC↗ |
| DIAZ REINALDO M | Director | A Award deriv | 2023-06-13 | 2023-06-15 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Sullivan Lynne Marie | Director | A Award deriv | 2023-06-13 | 2023-06-15 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Mathers Edward T | Director | A Award deriv | 2023-06-13 | 2023-06-15 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Hopfner Robert Lorne | Director | P Buy | 2023-05-12 | 2023-05-15 | 228,702 | $6.25 | $1.43M | 3,661,518 | SEC↗ |
| Hopfner Robert Lorne | Director | P Buy | 2023-05-11 | 2023-05-15 | 219,230 | $6.48 | $1.42M | 3,432,816 | SEC↗ |
| Bolte Axel | Director | A Award deriv | 2023-05-01 | 2023-05-03 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Winton Matthew | COO | A Award deriv | 2023-04-03 | 2023-04-04 | 250,000 | — | $0 | 250,000 | SEC↗ |
| Treco Douglas A | CEO | A Award deriv | 2023-04-01 | 2023-04-04 | 800,000 | — | $0 | 800,000 | SEC↗ |
| Treco Douglas A | CEO | A Award deriv | 2023-04-01 | 2023-04-04 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Subramanian Sanjay | SVP, CFO | A Award | 2023-03-31 | 2023-04-04 | 979 | $2.21 | $2.2K | 28,079 | SEC↗ |
| Bolte Axel | Director | A Award | 2023-03-31 | 2023-04-04 | 4,806 | $2.21 | $10.6K | 266,696 | SEC↗ |
| Hopfner Robert Lorne | Director | P Buy | 2023-03-29 | 2023-03-30 | 344,592 | $4.54 | $1.56M | 3,213,586 | SEC↗ |
| Hopfner Robert Lorne | Director | P Buy | 2023-03-28 | 2023-03-29 | 156,766 | $4.16 | $652.1K | 2,868,994 | SEC↗ |
| Hopfner Robert Lorne | Director | P Buy | 2023-03-27 | 2023-03-29 | 51,074 | $3.70 | $189.0K | 2,712,228 | SEC↗ |
| Subramanian Sanjay | SVP, CFO | A Award deriv | 2023-03-23 | 2023-03-27 | 135,000 | — | $0 | 135,000 | SEC↗ |
| Bjarke Henric Bjorn | SVP, COO | P Buy | 2022-12-15 | 2022-12-19 | 21,500 | $1.39 | $29.9K | 105,441 | SEC↗ |
| Bjarke Henric Bjorn | SVP, COO | A Award | 2022-09-30 | 2022-10-04 | 3,315 | $2.28 | $7.6K | 83,941 | SEC↗ |
| Bolte Axel | Chief Executive Officer | A Award | 2022-09-30 | 2022-10-04 | 3,315 | $2.28 | $7.6K | 261,890 | SEC↗ |
| Bhagat Sarah M | Director | A Award deriv | 2022-06-10 | 2022-06-14 | 9,367 | — | $0 | 9,367 | SEC↗ |
| DIAZ REINALDO M | Director | A Award deriv | 2022-06-10 | 2022-06-14 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Edwards Martin | Director | A Award deriv | 2022-06-10 | 2022-06-14 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Hopfner Robert Lorne | Director | A Award deriv | 2022-06-10 | 2022-06-14 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Sullivan Lynne Marie | Director | A Award deriv | 2022-06-10 | 2022-06-14 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Treco Douglas A | Director | A Award deriv | 2022-06-10 | 2022-06-14 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Mathers Edward T | Director | A Award deriv | 2022-06-10 | 2022-06-14 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Subramanian Sanjay | SVP, CFO | P Buy | 2022-04-19 | 2022-04-20 | 27,100 | $3.69 | $100.0K | 27,100 | SEC↗ |
| Bolte Axel | Chief Executive Officer | P Buy | 2022-04-19 | 2022-04-20 | 67,750 | $3.69 | $250.0K | 258,575 | SEC↗ |
| Bjarke Henric Bjorn | SVP, COO | P Buy | 2022-04-19 | 2022-04-20 | 27,100 | $3.69 | $100.0K | 80,626 | SEC↗ |
| Hopfner Robert Lorne | Director | P Buy | 2022-04-19 | 2022-04-20 | 1,070,000 | $3.69 | $3.95M | 2,661,154 | SEC↗ |
| Pivotal bioVenture Partners Fu | Director | P Buy | 2022-04-19 | 2022-04-20 | 1,070,000 | $3.69 | $3.95M | 2,661,154 | SEC↗ |
| Longitude Capital Partners III | 10% Owner | P Buy | 2022-04-19 | 2022-04-21 | 1,355,000 | $3.69 | $5.00M | 4,174,379 | SEC↗ |
| Subramanian Sanjay | SVP, CFO | A Award deriv | 2022-03-21 | 2022-03-22 | 180,000 | — | $0 | 180,000 | SEC↗ |
| Bjarke Henric Bjorn | SVP, COO | A Award deriv | 2022-02-24 | 2022-02-28 | 115,000 | — | $0 | 115,000 | SEC↗ |
| Bolte Axel | Chief Executive Officer | A Award deriv | 2022-02-24 | 2022-02-28 | 275,000 | — | $0 | 275,000 | SEC↗ |
| Bolte Axel | Chief Executive Officer | M Exercise deriv | 2021-06-24 | 2021-06-25 | 66,788 | — | $0 | 100,480 | SEC↗ |
| Bolte Axel | Chief Executive Officer | S Sale | 2021-06-24 | 2021-06-25 | 66,788 | — | $0 | 190,825 | SEC↗ |
| Bolte Axel | Chief Executive Officer | M Exercise | 2021-06-24 | 2021-06-25 | 66,788 | $0.98 | $65.5K | 257,613 | SEC↗ |
| Inozyme Pharma, Inc. | Director | A Award deriv | 2021-06-23 | 2021-06-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| DIAZ REINALDO M | Director | A Award deriv | 2021-06-23 | 2021-06-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Hopfner Robert Lorne | Director | A Award deriv | 2021-06-23 | 2021-06-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Sullivan Lynne Marie | Director | A Award deriv | 2021-06-23 | 2021-06-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Treco Douglas A | Director | A Award deriv | 2021-06-23 | 2021-06-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Edwards Martin | Director | A Award deriv | 2021-06-23 | 2021-06-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Mathers Edward T | Director | A Award deriv | 2021-06-23 | 2021-06-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Bhagat Sarah M | Director | A Award deriv | 2021-06-23 | 2021-06-25 | 9,367 | — | $0 | 9,367 | SEC↗ |
| DiPalma Stephen J. | Interim CFO | A Award deriv | 2021-05-17 | 2021-05-18 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Basso Stephen | SVP Finance (PFO) | A Award deriv | 2021-03-24 | 2021-03-25 | 13,000 | — | $0 | 13,000 | SEC↗ |
| Basso Stephen | SVP Finance (PFO) | A Award deriv | 2021-03-04 | 2021-03-17 | 27,000 | — | $0 | 27,000 | SEC↗ |
| Bjarke Henric Bjorn | SVP, COO | A Award deriv | 2021-03-04 | 2021-03-17 | 51,000 | — | $0 | 51,000 | SEC↗ |
| Bolte Axel | Chief Executive Officer | A Award deriv | 2021-03-04 | 2021-03-17 | 117,000 | — | $0 | 117,000 | SEC↗ |
| Jungles Steven J | SVP, CTO | A Award deriv | 2021-03-04 | 2021-03-17 | 42,000 | — | $0 | 42,000 | SEC↗ |
| Wenkert Deborah | SVP, CMO | A Award deriv | 2021-02-02 | 2021-02-04 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Novo Holdings A/S | 10% Owner | S Sale | 2021-01-28 | 2021-02-01 | 375,000 | $21.00 | $7.88M | 2,194,379 | SEC↗ |
| Bolte Axel | Chief Executive Officer | A Award deriv | 2021-01-13 | 2021-01-14 | 159,187 | — | $0 | 159,187 | SEC↗ |
| Bolte Axel | Chief Executive Officer | A Award deriv | 2021-01-13 | 2021-01-14 | 66,788 | — | $0 | 66,788 | SEC↗ |
| Basso Stephen | SVP Finance (PFO) | A Award deriv | 2021-01-13 | 2021-01-14 | 41,794 | — | $0 | 41,794 | SEC↗ |
| Bjarke Henric Bjorn | SVP, COO | A Award deriv | 2021-01-13 | 2021-01-14 | 51,105 | — | $0 | 51,105 | SEC↗ |
| Huertas Pedro | SVP, CMO | A Award deriv | 2021-01-13 | 2021-01-14 | 36,074 | — | $0 | 36,074 | SEC↗ |
| Jungles Steven J | SVP, CTO | A Award deriv | 2021-01-13 | 2021-01-14 | 44,315 | — | $0 | 44,315 | SEC↗ |
| HEALY JAMES | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-28 | 11,888,112 | — | $0 | 0 | SEC↗ |
| ALEXION PHARMACEUTICALS, INC. | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-28 | 8,294,360 | — | $0 | 0 | SEC↗ |
| Hopfner Robert Lorne | Director, 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-28 | 10,489,510 | — | $0 | 0 | SEC↗ |
| Schlessinger Joseph | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-28 | 100,000 | — | $0 | 0 | SEC↗ |
| Pivotal bioVenture Partners Fu | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-28 | 10,489,510 | — | $0 | 0 | SEC↗ |
| Jungles Steven J | See Remarks | C Conversion deriv | 2020-07-28 | 2020-07-28 | 100,000 | — | $0 | 0 | SEC↗ |
| Tammenoms Bakker Juliet | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-28 | 1,398,600 | — | $0 | 0 | SEC↗ |
| Tammenoms Bakker Juliet | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-28 | 15,000,000 | — | $0 | 0 | SEC↗ |
| New Enterprise Associates 15, | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-28 | 2,000,533 | — | $0 | 0 | SEC↗ |
| New Enterprise Associates 15, | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-28 | 187,156 | — | $0 | 0 | SEC↗ |
| Kolchinsky Peter | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-28 | 10,489,510 | — | $0 | 0 | SEC↗ |
| Rock Springs Capital LLC | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-28 | 3,496,504 | — | $0 | 0 | SEC↗ |
| Sanofi | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-29 | 3,279,720 | — | $0 | 0 | SEC↗ |
| Novo Holdings A/S | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-29 | 1,398,600 | — | $0 | 0 | SEC↗ |
| Novo Holdings A/S | 10% Owner | C Conversion deriv | 2020-07-28 | 2020-07-29 | 15,000,000 | — | $0 | 0 | SEC↗ |
| HEALY JAMES | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 1,590,808 | — | $0 | 1,590,808 | SEC↗ |
| HEALY JAMES | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 437,500 | $16.00 | $7.00M | 2,028,308 | SEC↗ |
| ALEXION PHARMACEUTICALS, INC. | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 1,109,910 | — | $0 | 1,109,910 | SEC↗ |
| Hopfner Robert Lorne | Director, 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 1,403,654 | — | $0 | 1,403,654 | SEC↗ |
| Hopfner Robert Lorne | Director, 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 187,500 | $16.00 | $3.00M | 1,591,154 | SEC↗ |
| Schlessinger Joseph | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 13,381 | — | $0 | 286,479 | SEC↗ |
| Pivotal bioVenture Partners Fu | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 187,500 | $16.00 | $3.00M | 1,591,154 | SEC↗ |
| Pivotal bioVenture Partners Fu | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 1,403,654 | — | $0 | 1,403,654 | SEC↗ |
| Jungles Steven J | See Remarks | C Conversion | 2020-07-28 | 2020-07-28 | 13,381 | — | $0 | 55,417 | SEC↗ |
| Tammenoms Bakker Juliet | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 187,154 | — | $0 | 2,194,379 | SEC↗ |
| Tammenoms Bakker Juliet | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 625,000 | $16.00 | $10.00M | 2,819,379 | SEC↗ |
| Tammenoms Bakker Juliet | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 2,007,225 | — | $0 | 2,007,225 | SEC↗ |
| New Enterprise Associates 15, | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 187,156 | — | $0 | 2,187,689 | SEC↗ |
| New Enterprise Associates 15, | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 250,000 | $16.00 | $4.00M | 2,437,689 | SEC↗ |
| New Enterprise Associates 15, | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 2,000,533 | — | $0 | 2,000,533 | SEC↗ |
| BASKETT FOREST | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 187,156 | — | $0 | 2,187,689 | SEC↗ |
| BASKETT FOREST | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 250,000 | $16.00 | $4.00M | 2,437,689 | SEC↗ |
| BASKETT FOREST | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 2,000,533 | — | $0 | 2,000,533 | SEC↗ |
| Florence Anthony A. Jr. | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 187,156 | — | $0 | 2,187,689 | SEC↗ |
| Florence Anthony A. Jr. | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 250,000 | $16.00 | $4.00M | 2,437,689 | SEC↗ |
| Florence Anthony A. Jr. | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 2,000,533 | — | $0 | 2,000,533 | SEC↗ |
| Makhzoumi Mohamad | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 2,000,533 | — | $0 | 2,000,533 | SEC↗ |
| Makhzoumi Mohamad | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 187,156 | — | $0 | 2,187,689 | SEC↗ |
| Makhzoumi Mohamad | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 250,000 | $16.00 | $4.00M | 2,437,689 | SEC↗ |
| MAKOWER JOSHUA | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 250,000 | $16.00 | $4.00M | 2,437,689 | SEC↗ |
| MAKOWER JOSHUA | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 187,156 | — | $0 | 2,187,689 | SEC↗ |
| MAKOWER JOSHUA | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 2,000,533 | — | $0 | 2,000,533 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 250,000 | $16.00 | $4.00M | 2,437,689 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 187,156 | — | $0 | 2,187,689 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 2,000,533 | — | $0 | 2,000,533 | SEC↗ |
| Sonsini Peter W. | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 187,156 | — | $0 | 2,187,689 | SEC↗ |
| Sonsini Peter W. | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 250,000 | $16.00 | $4.00M | 2,437,689 | SEC↗ |
| Sonsini Peter W. | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 2,000,533 | — | $0 | 2,000,533 | SEC↗ |
| Kolchinsky Peter | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 1,403,653 | — | $0 | 1,403,653 | SEC↗ |
| Kolchinsky Peter | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 600,000 | $16.00 | $9.60M | 2,003,653 | SEC↗ |
| Rock Springs Capital LLC | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 24,000 | $16.00 | $384.0K | 1,067,884 | SEC↗ |
| Rock Springs Capital LLC | 10% Owner | P Buy | 2020-07-28 | 2020-07-28 | 576,000 | $16.00 | $9.22M | 1,043,884 | SEC↗ |
| Rock Springs Capital LLC | 10% Owner | C Conversion | 2020-07-28 | 2020-07-28 | 467,884 | — | $0 | 467,884 | SEC↗ |
| Sanofi | 10% Owner | C Conversion | 2020-07-28 | 2020-07-29 | 438,875 | — | $0 | 438,875 | SEC↗ |
| Sanofi | 10% Owner | P Buy | 2020-07-28 | 2020-07-29 | 81,250 | $16.00 | $1.30M | 520,125 | SEC↗ |
| Novo Holdings A/S | 10% Owner | C Conversion | 2020-07-28 | 2020-07-29 | 2,194,379 | — | $0 | 2,194,379 | SEC↗ |
| Novo Holdings A/S | 10% Owner | P Buy | 2020-07-28 | 2020-07-29 | 375,000 | $16.00 | $6.00M | 2,569,379 | SEC↗ |
| BASKETT FOREST | 10% Owner | C Conversion deriv | 2020-07-25 | 2020-07-28 | 2,000,533 | — | $0 | 0 | SEC↗ |
| BASKETT FOREST | 10% Owner | C Conversion deriv | 2020-07-25 | 2020-07-28 | 187,156 | — | $0 | 0 | SEC↗ |
| Florence Anthony A. Jr. | 10% Owner | C Conversion deriv | 2020-07-25 | 2020-07-28 | 187,156 | — | $0 | 0 | SEC↗ |
| Florence Anthony A. Jr. | 10% Owner | C Conversion deriv | 2020-07-25 | 2020-07-28 | 2,000,533 | — | $0 | 0 | SEC↗ |
| Makhzoumi Mohamad | 10% Owner | C Conversion deriv | 2020-07-25 | 2020-07-28 | 2,000,533 | — | $0 | 0 | SEC↗ |
| Makhzoumi Mohamad | 10% Owner | C Conversion deriv | 2020-07-25 | 2020-07-28 | 187,156 | — | $0 | 0 | SEC↗ |
| MAKOWER JOSHUA | 10% Owner | C Conversion deriv | 2020-07-25 | 2020-07-28 | 2,000,533 | — | $0 | 0 | SEC↗ |
| MAKOWER JOSHUA | 10% Owner | C Conversion deriv | 2020-07-25 | 2020-07-28 | 187,156 | — | $0 | 0 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | C Conversion deriv | 2020-07-25 | 2020-07-28 | 2,000,533 | — | $0 | 0 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | C Conversion deriv | 2020-07-25 | 2020-07-28 | 187,156 | — | $0 | 0 | SEC↗ |
| Sonsini Peter W. | 10% Owner | C Conversion deriv | 2020-07-25 | 2020-07-28 | 2,000,533 | — | $0 | 0 | SEC↗ |
| Sonsini Peter W. | 10% Owner | C Conversion deriv | 2020-07-25 | 2020-07-28 | 187,156 | — | $0 | 0 | SEC↗ |
| Basso Stephen | Senior Vice President, Finan | A Award deriv | 2020-07-23 | 2020-07-24 | 27,433 | — | $0 | 27,433 | SEC↗ |
| Bhagat Sarah M | Director | A Award deriv | 2020-07-23 | 2020-07-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Sullivan Lynne Marie | Director | A Award deriv | 2020-07-23 | 2020-07-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| DIAZ REINALDO M | Director | A Award deriv | 2020-07-23 | 2020-07-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Hopfner Robert Lorne | Director | A Award deriv | 2020-07-23 | 2020-07-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Bolte Axel | See Remarks | A Award deriv | 2020-07-23 | 2020-07-24 | 287,706 | — | $0 | 287,706 | SEC↗ |
| Bjarke Henric Bjorn | See Remarks | A Award deriv | 2020-07-23 | 2020-07-24 | 32,905 | — | $0 | 32,905 | SEC↗ |
| Edwards Martin | Director | A Award deriv | 2020-07-23 | 2020-07-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Treco Douglas A | Director | A Award deriv | 2020-07-23 | 2020-07-24 | 9,367 | — | $0 | 9,367 | SEC↗ |
| Huertas Pedro | See Remarks | A Award deriv | 2020-07-23 | 2020-07-24 | 43,951 | — | $0 | 43,951 | SEC↗ |
| Mathers Edward T | Director | A Award deriv | 2020-07-23 | 2020-07-24 | 9,367 | — | $0 | 9,367 | SEC↗ |