Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
$23.83M
55 trades · 4 insiders
Net · 90d
$-23.83M
Insiders on file
30
Daily buy vs sell · 90 days
■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Bitterman Kevin | Director | 131 | $8.00M | $71.38M | 2026-10-21 |
| Quisel John D | Chief Executive Officer, Director | 75 | $0 | $20.06M | 2026-09-15 |
| Yu Jonathan Yen-Wen | Chief Operating Officer | 48 | $0 | $6.50M | 2026-08-25 |
| Khara Rahul | General Counsel | 54 | $0 | $4.00M | 2026-08-06 |
| Nicholson Donald William | Director | 5 | $0 | $0 | 2026-06-18 |
| White William Richard | Director | 70 | $0 | $2.96M | 2026-06-18 |
| Chin Mark | Director | 5 | $0 | $0 | 2026-06-18 |
| AHMED NADIM | Director | 2 | $0 | $0 | 2026-06-18 |
| Ratcliffe Liam | Director | 5 | $0 | $0 | 2026-06-18 |
| GEMAYEL GEORGES | Director | 6 | $0 | $0 | 2026-06-18 |
| Franchi Jean M. | Chief Financial Officer | 16 | $0 | $1.72M | 2026-04-14 |
| Savage William Jacob | Chief Medical Officer | 61 | $0 | $5.60M | 2026-04-13 |
| Stephenson Pamela | Chief Commercial Officer | 8 | $0 | $518.9K | 2026-02-17 |
| AI DMI LLC | 10% Owner | 1 | $0 | $59.87M | 2025-10-22 |
| Ashiya Mona | Director, 10% Owner | 51 | $5.50M | $52.70M | 2025-06-11 |
| ORBIMED ADVISORS LLC | Director, 10% Owner | 6 | $2.50M | $310.5K | 2025-03-24 |
| OrbiMed Capital GP VI LLC | Director, 10% Owner | 28 | $0 | $19.80M | 2025-03-21 |
| OrbiMed Genesis GP LLC | Director | 17 | $3.00M | $32.59M | 2024-06-17 |
| Access Industries Holdings LLC | 10% Owner | 1 | $0 | $0 | 2024-06-17 |
| Atlas Venture Associates X, LLC | 10% Owner | 3 | $0 | $10.15M | 2024-01-23 |
| Bryce Joanne | Chief Financial Officer | 29 | $0 | $1.09M | 2024-01-10 |
| Atlas Venture Associates Opportunity I, L.P. | 10% Owner | 7 | $0 | $22.05M | 2024-01-10 |
| Atlas Venture Associates Opportunity I, LLC | 10% Owner | 22 | $0 | $11.68M | 2023-12-14 |
| Atlas Venture Fund X, L.P. | 10% Owner | 3 | $0 | $18.99M | 2023-09-16 |
| MacDonald Brian Richard | Chief Innovation Officer | 11 | $0 | $711.1K | 2023-06-30 |
| Novo Holdings A/S | 10% Owner | 1 | $0 | $57.63M | 2023-06-28 |
| Blavatnik Len | 10% Owner | 1 | $10.00M | $0 | 2023-06-16 |
| ACCESS INDUSTRIES MANAGEMENT, LLC | 10% Owner | 1 | $10.00M | $0 | 2023-02-15 |
| Backstrom Jay T. | Director | 1 | $0 | $0 | 2022-12-29 |
| ATLAS VENTURE ASSOCIATES X, L.P. | 10% Owner | 2 | $0 | $0 | 2022-12-29 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Bitterman Kevin | Director | S Sale | 2026-10-21 | 2026-10-21 | 266 | $80.23 | $21.3K | 12,991 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-10-21 | 2026-10-21 | 11,470 | $80.23 | $920.2K | 293,430 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-10-21 | 2026-10-21 | 13,783 | $80.23 | $1.11M | 296,277 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-10-20 | 2026-10-21 | 55 | $79.95 | $4.4K | 13,257 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-10-20 | 2026-10-21 | 2,388 | $79.95 | $190.9K | 304,900 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-10-20 | 2026-10-21 | 2,869 | $79.95 | $229.4K | 310,060 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-10-19 | 2026-10-21 | 115 | $79.97 | $9.2K | 13,312 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-10-19 | 2026-10-21 | 4,942 | $79.97 | $395.2K | 307,288 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-10-19 | 2026-10-21 | 5,937 | $79.97 | $474.8K | 312,929 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise deriv | 2026-09-15 | 2026-09-16 | 36,000 | — | $0 | 150,120 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise | 2026-09-15 | 2026-09-16 | 36,000 | $1.01 | $36.4K | 262,064 | SEC↗ |
| Quisel John D | Chief Executive Officer, Dir | M Exercise deriv | 2026-09-15 | 2026-09-16 | 36,000 | — | $0 | 150,120 | SEC↗ |
| Quisel John D | Chief Executive Officer, Dir | M Exercise | 2026-09-15 | 2026-09-16 | 36,000 | $1.01 | $36.4K | 262,064 | SEC↗ |
| Bitterman Kevin | Director | M Exercise deriv | 2026-09-11 | 2026-09-15 | 7,136 | — | $0 | 0 | SEC↗ |
| Bitterman Kevin | Director | M Exercise deriv | 2026-09-11 | 2026-09-15 | 10,000 | — | $0 | 0 | SEC↗ |
| Bitterman Kevin | Director | M Exercise deriv | 2026-09-11 | 2026-09-15 | 10,000 | — | $0 | 0 | SEC↗ |
| Bitterman Kevin | Director | M Exercise | 2026-09-11 | 2026-09-15 | 7,136 | $45.69 | $326.0K | 7,136 | SEC↗ |
| Bitterman Kevin | Director | M Exercise | 2026-09-11 | 2026-09-15 | 10,000 | $38.85 | $388.5K | 17,136 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-11 | 2026-09-15 | 27,136 | $70.11 | $1.90M | 0 | SEC↗ |
| Bitterman Kevin | Director | M Exercise | 2026-09-11 | 2026-09-15 | 10,000 | $50.86 | $508.6K | 27,136 | SEC↗ |
| Bitterman Kevin | Director | M Exercise deriv | 2026-09-11 | 2026-09-15 | 10,000 | — | $0 | 0 | SEC↗ |
| Bitterman Kevin | Director | M Exercise deriv | 2026-09-11 | 2026-09-15 | 10,000 | — | $0 | 0 | SEC↗ |
| Bitterman Kevin | Director | M Exercise deriv | 2026-09-11 | 2026-09-15 | 7,136 | — | $0 | 0 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-11 | 2026-09-15 | 27,136 | $70.11 | $1.90M | 0 | SEC↗ |
| Bitterman Kevin | Director | M Exercise | 2026-09-11 | 2026-09-15 | 10,000 | $50.86 | $508.6K | 27,136 | SEC↗ |
| Bitterman Kevin | Director | M Exercise | 2026-09-11 | 2026-09-15 | 10,000 | $38.85 | $388.5K | 17,136 | SEC↗ |
| Bitterman Kevin | Director | M Exercise | 2026-09-11 | 2026-09-15 | 7,136 | $45.69 | $326.0K | 7,136 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-04 | 2026-09-09 | 759 | $79.96 | $60.7K | 312,230 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-04 | 2026-09-09 | 18 | $79.96 | $1.4K | 13,427 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-04 | 2026-09-09 | 912 | $79.96 | $72.9K | 318,866 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-04 | 2026-09-09 | 18 | $79.96 | $1.4K | 13,427 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-04 | 2026-09-09 | 759 | $79.96 | $60.7K | 312,230 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-04 | 2026-09-09 | 912 | $79.96 | $72.9K | 318,866 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-03 | 2026-09-03 | 2,339 | $79.98 | $187.1K | 312,989 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-03 | 2026-09-03 | 2,810 | $79.98 | $224.7K | 319,778 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-03 | 2026-09-03 | 54 | $79.98 | $4.3K | 13,445 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-03 | 2026-09-03 | 54 | $79.98 | $4.3K | 13,445 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-03 | 2026-09-03 | 2,339 | $79.98 | $187.1K | 312,989 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-03 | 2026-09-03 | 2,810 | $79.98 | $224.7K | 319,778 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-02 | 2026-09-03 | 511 | $80.17 | $41.0K | 13,501 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-02 | 2026-09-03 | 2 | $80.98 | $162 | 13,499 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-02 | 2026-09-03 | 9 | $80.98 | $729 | 315,328 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-02 | 2026-09-03 | 10 | $80.98 | $810 | 322,588 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-02 | 2026-09-03 | 22,090 | $80.17 | $1.77M | 315,337 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-02 | 2026-09-03 | 26,542 | $80.17 | $2.13M | 322,598 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-02 | 2026-09-03 | 2 | $80.98 | $162 | 13,499 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-02 | 2026-09-03 | 9 | $80.98 | $729 | 315,328 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-02 | 2026-09-03 | 10 | $80.98 | $810 | 322,588 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-02 | 2026-09-03 | 511 | $80.17 | $41.0K | 13,501 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-02 | 2026-09-03 | 22,090 | $80.17 | $1.77M | 315,337 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-02 | 2026-09-03 | 26,542 | $80.17 | $2.13M | 322,598 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-01 | 2026-09-03 | 1 | $79.95 | $80 | 14,012 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-01 | 2026-09-03 | 58 | $79.95 | $4.6K | 337,427 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-01 | 2026-09-03 | 70 | $79.95 | $5.6K | 349,140 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-01 | 2026-09-03 | 1 | $79.95 | $80 | 14,012 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-01 | 2026-09-03 | 58 | $79.95 | $4.6K | 337,427 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2026-09-01 | 2026-09-03 | 70 | $79.95 | $5.6K | 349,140 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise deriv | 2026-08-25 | 2026-08-26 | 8,796 | — | $0 | 13,847 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise | 2026-08-25 | 2026-08-26 | 8,796 | $13.50 | $118.7K | 63,120 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2026-08-25 | 2026-08-26 | 8,796 | $83.12 | $731.1K | 54,324 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise deriv | 2026-08-25 | 2026-08-26 | 8,796 | — | $0 | 13,847 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2026-08-25 | 2026-08-26 | 8,796 | $83.12 | $731.1K | 54,324 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise | 2026-08-25 | 2026-08-26 | 8,796 | $13.50 | $118.7K | 63,120 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise deriv | 2026-08-24 | 2026-08-26 | 300 | — | $0 | 22,643 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise | 2026-08-24 | 2026-08-26 | 300 | $13.50 | $4.0K | 54,624 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2026-08-24 | 2026-08-26 | 300 | $82.53 | $24.8K | 54,324 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise deriv | 2026-08-24 | 2026-08-26 | 300 | — | $0 | 22,643 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2026-08-24 | 2026-08-26 | 300 | $82.53 | $24.8K | 54,324 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise | 2026-08-24 | 2026-08-26 | 300 | $13.50 | $4.0K | 54,624 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise deriv | 2026-08-17 | 2026-08-18 | 33,000 | — | $0 | 91,586 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2026-08-17 | 2026-08-18 | 8,400 | $78.11 | $656.1K | 250,664 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2026-08-17 | 2026-08-18 | 11,888 | $79.84 | $949.1K | 226,064 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2026-08-17 | 2026-08-18 | 12,712 | $79.20 | $1.01M | 237,952 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise | 2026-08-17 | 2026-08-18 | 33,000 | $13.50 | $445.5K | 259,064 | SEC↗ |
| Quisel John D | Chief Executive Officer, Dir | M Exercise deriv | 2026-08-17 | 2026-08-18 | 33,000 | — | $0 | 91,586 | SEC↗ |
| Quisel John D | Chief Executive Officer, Dir | S Sale | 2026-08-17 | 2026-08-18 | 11,888 | $79.84 | $949.2K | 226,064 | SEC↗ |
| Quisel John D | Chief Executive Officer, Dir | S Sale | 2026-08-17 | 2026-08-18 | 12,712 | $79.20 | $1.01M | 237,952 | SEC↗ |
| Quisel John D | Chief Executive Officer, Dir | S Sale | 2026-08-17 | 2026-08-18 | 8,400 | $78.11 | $656.1K | 250,664 | SEC↗ |
| Quisel John D | Chief Executive Officer, Dir | M Exercise | 2026-08-17 | 2026-08-18 | 33,000 | $13.50 | $445.5K | 259,064 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise deriv | 2026-08-12 | 2026-08-14 | 804 | — | $0 | 22,943 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise | 2026-08-12 | 2026-08-14 | 804 | $13.50 | $10.9K | 55,128 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2026-08-12 | 2026-08-14 | 804 | $82.64 | $66.4K | 54,324 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise deriv | 2026-08-12 | 2026-08-14 | 804 | — | $0 | 22,943 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2026-08-12 | 2026-08-14 | 804 | $82.64 | $66.4K | 54,324 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise | 2026-08-12 | 2026-08-14 | 804 | $13.50 | $10.9K | 55,128 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise deriv | 2026-08-06 | 2026-08-07 | 5,000 | — | $0 | 49,804 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise | 2026-08-06 | 2026-08-07 | 5,000 | $14.69 | $73.5K | 57,324 | SEC↗ |
| Khara Rahul | Chief Legal Officer | S Sale | 2026-08-06 | 2026-08-07 | 5,000 | $80.00 | $400.0K | 52,324 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise deriv | 2026-08-06 | 2026-08-07 | 5,000 | — | $0 | 49,804 | SEC↗ |
| Khara Rahul | Chief Legal Officer | S Sale | 2026-08-06 | 2026-08-07 | 5,000 | $80.00 | $400.0K | 52,324 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise | 2026-08-06 | 2026-08-07 | 5,000 | $14.69 | $73.5K | 57,324 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise deriv | 2026-07-13 | 2026-07-14 | 7,416 | — | $0 | 124,586 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise deriv | 2026-07-13 | 2026-07-14 | 25,584 | — | $0 | 15,791 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2026-07-13 | 2026-07-14 | 9,704 | $74.27 | $720.7K | 249,360 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise | 2026-07-13 | 2026-07-14 | 7,416 | $13.50 | $100.1K | 259,064 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise | 2026-07-13 | 2026-07-14 | 25,584 | $9.86 | $252.3K | 251,648 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2026-07-13 | 2026-07-14 | 6,400 | $76.05 | $486.7K | 226,064 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2026-07-13 | 2026-07-14 | 16,896 | $74.95 | $1.27M | 232,464 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise deriv | 2026-07-07 | 2026-07-09 | 100 | — | $0 | 23,747 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2026-07-07 | 2026-07-09 | 100 | $82.50 | $8.3K | 54,324 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise | 2026-07-07 | 2026-07-09 | 100 | $13.50 | $1.4K | 54,424 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise deriv | 2026-06-29 | 2026-06-30 | 1,649 | — | $0 | 54,804 | SEC↗ |
| Khara Rahul | Chief Legal Officer | S Sale | 2026-06-29 | 2026-06-30 | 1,649 | $75.00 | $123.7K | 52,173 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise | 2026-06-29 | 2026-06-30 | 1,649 | $14.69 | $24.2K | 53,822 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise deriv | 2026-06-26 | 2026-06-30 | 300 | — | $0 | 23,847 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise deriv | 2026-06-26 | 2026-06-30 | 851 | — | $0 | 56,453 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2026-06-26 | 2026-06-30 | 300 | $72.50 | $21.8K | 54,324 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise | 2026-06-26 | 2026-06-30 | 300 | $13.50 | $4.0K | 54,624 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise | 2026-06-26 | 2026-06-30 | 851 | $14.69 | $12.5K | 53,024 | SEC↗ |
| Khara Rahul | Chief Legal Officer | S Sale | 2026-06-26 | 2026-06-30 | 851 | $75.00 | $63.8K | 52,173 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise deriv | 2026-06-22 | 2026-06-24 | 9,700 | — | $0 | 24,147 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2026-06-22 | 2026-06-24 | 9,700 | $72.66 | $704.8K | 54,324 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise | 2026-06-22 | 2026-06-24 | 9,700 | $13.50 | $130.9K | 64,024 | SEC↗ |
| AHMED NADIM | Director | A Award deriv | 2026-06-18 | 2026-06-23 | 5,176 | — | $0 | 5,176 | SEC↗ |
| Bitterman Kevin | Director | A Award deriv | 2026-06-18 | 2026-06-23 | 6,212 | — | $0 | 6,212 | SEC↗ |
| Chin Mark | Director | A Award deriv | 2026-06-18 | 2026-06-23 | 6,212 | — | $0 | 6,212 | SEC↗ |
| GEMAYEL GEORGES | Director | A Award deriv | 2026-06-18 | 2026-06-23 | 6,212 | — | $0 | 6,212 | SEC↗ |
| Nicholson Donald William | Director | A Award deriv | 2026-06-18 | 2026-06-23 | 6,212 | — | $0 | 6,212 | SEC↗ |
| Ratcliffe Liam | Director | A Award deriv | 2026-06-18 | 2026-06-23 | 6,212 | — | $0 | 6,212 | SEC↗ |
| White William Richard | Director | A Award deriv | 2026-06-18 | 2026-06-23 | 6,212 | — | $0 | 6,212 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise deriv | 2026-06-18 | 2026-06-23 | 34,000 | — | $0 | 41,375 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise deriv | 2026-06-18 | 2026-06-23 | 7,500 | — | $0 | 57,304 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2026-06-18 | 2026-06-23 | 22,927 | $69.92 | $1.60M | 237,137 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2026-06-18 | 2026-06-23 | 9,522 | $70.70 | $673.2K | 227,615 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2026-06-18 | 2026-06-23 | 1,551 | $71.61 | $111.1K | 226,064 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise | 2026-06-18 | 2026-06-23 | 34,000 | $9.86 | $335.2K | 260,064 | SEC↗ |
| Khara Rahul | Chief Legal Officer | S Sale | 2026-06-18 | 2026-06-23 | 5,400 | $69.94 | $377.7K | 54,273 | SEC↗ |
| Khara Rahul | Chief Legal Officer | S Sale | 2026-06-18 | 2026-06-23 | 1,600 | $70.73 | $113.2K | 52,673 | SEC↗ |
| Khara Rahul | Chief Legal Officer | S Sale | 2026-06-18 | 2026-06-23 | 500 | $71.62 | $35.8K | 52,173 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise | 2026-06-18 | 2026-06-23 | 7,500 | $14.69 | $110.2K | 59,673 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise deriv | 2026-06-16 | 2026-06-18 | 5,261 | — | $0 | 1,753 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise deriv | 2026-06-16 | 2026-06-18 | 13,351 | — | $0 | 31,951 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2026-06-16 | 2026-06-18 | 11,651 | $68.76 | $801.1K | 61,285 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise | 2026-06-16 | 2026-06-18 | 5,261 | $9.86 | $51.9K | 59,585 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise | 2026-06-16 | 2026-06-18 | 13,351 | $9.86 | $131.6K | 72,936 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2026-06-16 | 2026-06-18 | 6,961 | $69.92 | $486.7K | 54,324 | SEC↗ |
| Franchi Jean M. | Chief Financial Officer | S Sale | 2026-04-14 | 2026-04-15 | 6,257 | $69.24 | $433.2K | 64,333 | SEC↗ |
| Franchi Jean M. | Chief Financial Officer | S Sale | 2026-04-13 | 2026-04-15 | 400 | $69.00 | $27.6K | 70,590 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | S Sale | 2026-04-13 | 2026-04-15 | 3,531 | $66.12 | $233.5K | 81,680 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | S Sale | 2026-04-13 | 2026-04-15 | 2,200 | $66.81 | $147.0K | 79,480 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | S Sale | 2026-03-02 | 2026-03-04 | 2,986 | $66.41 | $198.3K | 85,211 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | S Sale | 2026-03-02 | 2026-03-04 | 4,392 | $65.52 | $287.8K | 88,197 | SEC↗ |
| Franchi Jean M. | Chief Financial Officer | S Sale | 2026-02-25 | 2026-02-27 | 353 | $69.06 | $24.4K | 70,990 | SEC↗ |
| Franchi Jean M. | Chief Financial Officer | S Sale | 2026-02-18 | 2026-02-19 | 3,397 | $65.01 | $220.8K | 75,027 | SEC↗ |
| Franchi Jean M. | Chief Financial Officer | S Sale | 2026-02-18 | 2026-02-19 | 3,684 | $65.89 | $242.7K | 71,343 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2026-02-17 | 2026-02-17 | 13,264 | $62.86 | $833.8K | 226,064 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2026-02-17 | 2026-02-17 | 3,231 | $62.86 | $203.1K | 54,324 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | S Sale | 2026-02-17 | 2026-02-17 | 3,256 | $62.86 | $204.7K | 92,589 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | S Sale | 2026-02-17 | 2026-02-17 | 5,531 | $62.86 | $347.7K | 80,998 | SEC↗ |
| Khara Rahul | Chief Legal Officer | S Sale | 2026-02-17 | 2026-02-17 | 2,853 | $62.86 | $179.3K | 52,173 | SEC↗ |
| Franchi Jean M. | Chief Financial Officer | S Sale | 2026-02-17 | 2026-02-19 | 4,075 | $62.86 | $256.2K | 78,424 | SEC↗ |
| Quisel John D | Chief Executive Officer | A Award deriv | 2026-02-10 | 2026-02-11 | 82,800 | — | $0 | 82,800 | SEC↗ |
| Franchi Jean M. | Chief Financial Officer | A Award deriv | 2026-02-10 | 2026-02-11 | 25,500 | — | $0 | 25,500 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | A Award deriv | 2026-02-10 | 2026-02-11 | 25,500 | — | $0 | 25,500 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | A Award deriv | 2026-02-10 | 2026-02-11 | 25,500 | — | $0 | 25,500 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | A Award deriv | 2026-02-10 | 2026-02-11 | 25,500 | — | $0 | 25,500 | SEC↗ |
| Khara Rahul | Chief Legal Officer | A Award deriv | 2026-02-10 | 2026-02-11 | 25,500 | — | $0 | 25,500 | SEC↗ |
| Quisel John D | Chief Executive Officer | A Award | 2026-02-10 | 2026-02-11 | 55,200 | — | $0 | 239,328 | SEC↗ |
| Franchi Jean M. | Chief Financial Officer | A Award | 2026-02-10 | 2026-02-11 | 19,000 | — | $0 | 82,499 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | A Award | 2026-02-10 | 2026-02-11 | 17,000 | — | $0 | 57,555 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | A Award | 2026-02-10 | 2026-02-11 | 17,000 | — | $0 | 95,845 | SEC↗ |
| Stephenson Pamela | Chief Commercial Officer | A Award | 2026-02-10 | 2026-02-11 | 17,000 | — | $0 | 86,529 | SEC↗ |
| Khara Rahul | Chief Legal Officer | A Award | 2026-02-10 | 2026-02-11 | 17,000 | — | $0 | 55,026 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise deriv | 2026-01-20 | 2026-01-21 | 1,000 | — | $0 | 21,270 | SEC↗ |
| Khara Rahul | Chief Legal Officer | S Sale | 2026-01-20 | 2026-01-21 | 1,000 | $69.74 | $69.7K | 37,793 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise | 2026-01-20 | 2026-01-21 | 1,000 | $13.50 | $13.5K | 38,793 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise deriv | 2026-01-02 | 2026-01-05 | 6,500 | — | $0 | 22,270 | SEC↗ |
| Khara Rahul | Chief Legal Officer | S Sale | 2026-01-02 | 2026-01-05 | 350 | $77.67 | $27.2K | 43,943 | SEC↗ |
| Khara Rahul | Chief Legal Officer | M Exercise | 2026-01-02 | 2026-01-05 | 6,500 | $13.50 | $87.8K | 44,293 | SEC↗ |
| Khara Rahul | Chief Legal Officer | S Sale | 2026-01-02 | 2026-01-05 | 4,993 | $78.62 | $392.5K | 38,950 | SEC↗ |
| Khara Rahul | Chief Legal Officer | S Sale | 2026-01-02 | 2026-01-05 | 1,157 | $79.27 | $91.7K | 37,793 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | M Exercise deriv | 2025-12-22 | 2025-12-29 | 99 | — | $0 | 29,905 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | M Exercise deriv | 2025-12-22 | 2025-12-29 | 219 | — | $0 | 2,628 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | M Exercise deriv | 2025-12-22 | 2025-12-29 | 2,825 | — | $0 | 3,550 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | M Exercise | 2025-12-22 | 2025-12-29 | 99 | $13.50 | $1.3K | 78,845 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | M Exercise | 2025-12-22 | 2025-12-29 | 219 | $9.86 | $2.2K | 78,746 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | M Exercise | 2025-12-22 | 2025-12-29 | 2,825 | $9.86 | $27.9K | 78,527 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise deriv | 2025-12-19 | 2025-12-19 | 12,300 | — | $0 | 186,120 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise | 2025-12-19 | 2025-12-19 | 12,300 | $1.01 | $12.4K | 184,128 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-17 | 2025-12-18 | 213 | $91.47 | $19.5K | 337,485 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-17 | 2025-12-18 | 148 | $91.47 | $13.5K | 14,013 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-17 | 2025-12-18 | 393 | $91.47 | $35.9K | 349,210 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-16 | 2025-12-16 | 14,359 | $91.24 | $1.31M | 14,161 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-16 | 2025-12-16 | 35,898 | $91.24 | $3.28M | 349,603 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-16 | 2025-12-16 | 18,666 | $91.24 | $1.70M | 337,698 | SEC↗ |
| Bitterman Kevin | Director | M Exercise deriv | 2025-12-15 | 2025-12-16 | 7,000 | — | $0 | 0 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | S Sale | 2025-12-15 | 2025-12-16 | 3,642 | $90.60 | $330.0K | 85,153 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | S Sale | 2025-12-15 | 2025-12-16 | 9,151 | $91.44 | $836.8K | 76,002 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | S Sale | 2025-12-15 | 2025-12-16 | 300 | $92.23 | $27.7K | 75,702 | SEC↗ |
| Bitterman Kevin | Director | M Exercise | 2025-12-15 | 2025-12-16 | 7,000 | $13.50 | $94.5K | 7,000 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-15 | 2025-12-16 | 7,000 | $91.87 | $643.1K | 0 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-15 | 2025-12-16 | 28,913 | $91.18 | $2.64M | 389,422 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-15 | 2025-12-16 | 3,921 | $92.01 | $360.8K | 385,501 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-15 | 2025-12-16 | 14,811 | $91.18 | $1.35M | 358,413 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-15 | 2025-12-16 | 2,049 | $92.01 | $188.5K | 356,364 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-15 | 2025-12-16 | 11,427 | $91.18 | $1.04M | 30,092 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-15 | 2025-12-16 | 1,572 | $92.01 | $144.6K | 28,520 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-12 | 2025-12-16 | 1,371 | $93.80 | $128.6K | 41,519 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-12 | 2025-12-16 | 1,540 | $92.58 | $142.6K | 42,890 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-12 | 2025-12-16 | 6,570 | $92.05 | $604.8K | 44,430 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-12 | 2025-12-16 | 1,793 | $93.80 | $168.2K | 373,224 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-12 | 2025-12-16 | 8,527 | $92.05 | $784.9K | 377,022 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-12 | 2025-12-16 | 3,446 | $93.80 | $323.2K | 418,335 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-12 | 2025-12-16 | 3,852 | $92.58 | $356.6K | 421,781 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-12 | 2025-12-16 | 16,403 | $92.05 | $1.51M | 425,633 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-12-12 | 2025-12-16 | 2,005 | $92.58 | $185.6K | 375,017 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise deriv | 2025-12-11 | 2025-12-15 | 40,000 | — | $0 | 75,375 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2025-12-11 | 2025-12-15 | 16,888 | $93.65 | $1.58M | 171,828 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2025-12-11 | 2025-12-15 | 16,356 | $92.96 | $1.52M | 188,716 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2025-12-11 | 2025-12-15 | 4,337 | $92.21 | $399.9K | 205,072 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2025-12-11 | 2025-12-15 | 2,419 | $90.97 | $220.1K | 209,409 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise | 2025-12-11 | 2025-12-15 | 40,000 | $9.86 | $394.4K | 211,828 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise deriv | 2025-11-11 | 2025-11-13 | 30,000 | — | $0 | 7,941 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2025-11-11 | 2025-11-13 | 4,585 | $83.99 | $385.1K | 57,955 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2025-11-11 | 2025-11-13 | 8,015 | $83.15 | $666.4K | 62,540 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2025-11-11 | 2025-11-13 | 9,360 | $85.33 | $798.7K | 48,595 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | M Exercise | 2025-11-11 | 2025-11-13 | 30,000 | $2.65 | $79.5K | 70,555 | SEC↗ |
| Yu Jonathan Yen-Wen | Chief Operating Officer | S Sale | 2025-11-11 | 2025-11-13 | 8,040 | $85.91 | $690.7K | 40,555 | SEC↗ |
| AI DMI LLC | 10% Owner | S Sale | 2025-10-22 | 2025-10-24 | 744,047 | $80.47 | $59.87M | 2,814,379 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 2,251 | $89.70 | $201.9K | 396,094 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 2,251 | $89.70 | $201.9K | 452,580 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 13,014 | $88.91 | $1.16M | 398,345 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 13,014 | $88.91 | $1.16M | 454,831 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 5,065 | $87.37 | $442.5K | 411,359 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 5,066 | $87.37 | $442.6K | 467,845 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 3,000 | $86.13 | $258.4K | 416,424 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 3,000 | $86.13 | $258.4K | 472,911 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 1,125 | $84.89 | $95.5K | 419,424 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 1,125 | $84.89 | $95.5K | 475,911 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 10,094 | $90.66 | $915.1K | 442,486 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 10,095 | $90.66 | $915.2K | 385,999 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 450 | $91.88 | $41.3K | 442,036 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-17 | 2025-10-17 | 450 | $91.88 | $41.3K | 385,549 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-16 | 2025-10-17 | 1,425 | $77.11 | $109.9K | 477,036 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-15 | 2025-10-17 | 2,618 | $77.76 | $203.6K | 478,461 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-15 | 2025-10-17 | 19,542 | $77.16 | $1.51M | 481,079 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-08 | 2025-10-09 | 13,267 | $72.39 | $960.4K | 500,621 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-08 | 2025-10-09 | 8,219 | $68.26 | $561.0K | 564,363 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-08 | 2025-10-09 | 12,689 | $71.51 | $907.4K | 513,888 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-08 | 2025-10-09 | 25,400 | $70.54 | $1.79M | 526,577 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-08 | 2025-10-09 | 12,386 | $69.31 | $858.5K | 551,977 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-07 | 2025-10-09 | 11,378 | $68.01 | $773.8K | 579,243 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-10-07 | 2025-10-09 | 6,661 | $69.01 | $459.7K | 572,582 | SEC↗ |
| GEMAYEL GEORGES | Director | A Award deriv | 2025-09-16 | 2025-09-18 | 1,000 | — | $0 | 1,000 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise deriv | 2025-09-09 | 2025-09-11 | 10,000 | — | $0 | 198,420 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise | 2025-09-09 | 2025-09-11 | 10,000 | $1.01 | $10.1K | 171,828 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-08-22 | 2025-08-26 | 2,287 | $61.03 | $139.6K | 590,621 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-08-14 | 2025-08-15 | 7,212 | $60.99 | $439.9K | 592,908 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-08-13 | 2025-08-15 | 24,962 | $61.15 | $1.53M | 600,120 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-08-05 | 2025-08-07 | 395 | $60.95 | $24.1K | 625,082 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-07-30 | 2025-08-01 | 8,492 | $61.04 | $518.4K | 625,477 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-07-24 | 2025-07-25 | 13,033 | $61.17 | $797.2K | 633,969 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-07-23 | 2025-07-25 | 29,837 | $60.97 | $1.82M | 647,002 | SEC↗ |
| Bitterman Kevin | Director | S Sale | 2025-07-18 | 2025-07-22 | 664 | $61.13 | $40.6K | 676,839 | SEC↗ |
| Franchi Jean M. | Chief Financial Officer | S Sale | 2025-07-17 | 2025-07-18 | 2,031 | $59.00 | $119.8K | 63,499 | SEC↗ |
| AHMED NADIM | Director | A Award deriv | 2025-07-14 | 2025-07-16 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Franchi Jean M. | Chief Financial Officer | S Sale | 2025-07-10 | 2025-07-14 | 2,000 | $57.50 | $115.0K | 65,530 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise deriv | 2025-07-09 | 2025-07-11 | 34,800 | — | $0 | 115,375 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2025-07-09 | 2025-07-11 | 3,593 | $56.20 | $201.9K | 161,828 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2025-07-09 | 2025-07-11 | 31,207 | $55.23 | $1.72M | 165,421 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise | 2025-07-09 | 2025-07-11 | 34,800 | $9.86 | $343.1K | 196,628 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise deriv | 2025-07-03 | 2025-07-08 | 5,200 | — | $0 | 150,175 | SEC↗ |
| Quisel John D | Chief Executive Officer | S Sale | 2025-07-03 | 2025-07-08 | 5,200 | $55.09 | $286.5K | 161,828 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise | 2025-07-03 | 2025-07-08 | 5,200 | $9.86 | $51.3K | 167,028 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | M Exercise deriv | 2025-06-27 | 2025-07-01 | 29,659 | — | $0 | 6,375 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | M Exercise deriv | 2025-06-27 | 2025-07-01 | 2,411 | — | $0 | 2,847 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | M Exercise | 2025-06-27 | 2025-07-01 | 29,659 | $9.86 | $292.4K | 86,384 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | M Exercise | 2025-06-27 | 2025-07-01 | 2,411 | $9.86 | $23.8K | 88,795 | SEC↗ |
| Franchi Jean M. | Chief Financial Officer | S Sale | 2025-06-16 | 2025-06-18 | 2,000 | $52.26 | $104.5K | 67,530 | SEC↗ |
| Ashiya Mona | Director | A Award deriv | 2025-06-11 | 2025-06-13 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Bitterman Kevin | Director | A Award deriv | 2025-06-11 | 2025-06-13 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Chin Mark | Director | A Award deriv | 2025-06-11 | 2025-06-13 | 10,000 | — | $0 | 10,000 | SEC↗ |
| GEMAYEL GEORGES | Director | A Award deriv | 2025-06-11 | 2025-06-13 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Nicholson Donald William | Director | A Award deriv | 2025-06-11 | 2025-06-13 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Ratcliffe Liam | Director | A Award deriv | 2025-06-11 | 2025-06-13 | 10,000 | — | $0 | 10,000 | SEC↗ |
| White William Richard | Director | A Award deriv | 2025-06-11 | 2025-06-13 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | S Sale | 2025-06-06 | 2025-06-09 | 2,996 | $50.00 | $149.8K | 56,725 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | S Sale | 2025-05-20 | 2025-05-22 | 6,677 | $50.04 | $334.1K | 59,721 | SEC↗ |
| Savage William Jacob | Chief Medical Officer | S Sale | 2025-05-02 | 2025-05-06 | 2,100 | $50.17 | $105.4K | 66,398 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise deriv | 2025-04-07 | 2025-04-08 | 7,000 | — | $0 | 208,420 | SEC↗ |
| Quisel John D | Chief Executive Officer | M Exercise | 2025-04-07 | 2025-04-08 | 7,000 | $1.01 | $7.1K | 161,828 | SEC↗ |
| ORBIMED ADVISORS LLC | Director | S Sale | 2025-03-24 | 2025-03-26 | 1,956 | $54.11 | $105.8K | 482,308 | SEC↗ |
| ORBIMED ADVISORS LLC | Director | S Sale | 2025-03-24 | 2025-03-26 | 3,026 | $54.11 | $163.7K | 746,171 | SEC↗ |
| ORBIMED ADVISORS LLC | Director | S Sale | 2025-03-24 | 2025-03-26 | 756 | $54.11 | $40.9K | 186,541 | SEC↗ |
| Ashiya Mona | Director | S Sale | 2025-03-24 | 2025-03-26 | 756 | $54.11 | $40.9K | 186,541 | SEC↗ |
| Ashiya Mona | Director | S Sale | 2025-03-24 | 2025-03-26 | 3,026 | $54.11 | $163.7K | 746,171 | SEC↗ |
| Ashiya Mona | Director | S Sale | 2025-03-24 | 2025-03-26 | 1,956 | $54.11 | $105.8K | 482,308 | SEC↗ |
| OrbiMed Capital GP VI LLC | Director | S Sale | 2025-03-21 | 2025-03-21 | 1,320 | $54.00 | $71.3K | 187,297 | SEC↗ |
| OrbiMed Capital GP VI LLC | Director | S Sale | 2025-03-21 | 2025-03-21 | 5,279 | $54.00 | $285.1K | 749,197 | SEC↗ |
| OrbiMed Capital GP VI LLC | Director | S Sale | 2025-03-21 | 2025-03-21 | 3,412 | $54.00 | $184.2K | 484,264 | SEC↗ |
| Ashiya Mona | Director | S Sale | 2025-03-21 | 2025-03-21 | 3,412 | $54.00 | $184.2K | 484,264 | SEC↗ |
| Ashiya Mona | Director | S Sale | 2025-03-21 | 2025-03-21 | 5,279 | $54.00 | $285.1K | 749,197 | SEC↗ |
| Ashiya Mona | Director | S Sale | 2025-03-21 | 2025-03-21 | 1,320 | $54.00 | $71.3K | 187,297 | SEC↗ |
| OrbiMed Capital GP VI LLC | Director | S Sale | 2025-03-20 | 2025-03-21 | 364 | $54.01 | $19.7K | 188,617 | SEC↗ |
| OrbiMed Capital GP VI LLC | Director | S Sale | 2025-03-20 | 2025-03-21 | 1,457 | $54.01 | $78.7K | 754,476 | SEC↗ |
| OrbiMed Capital GP VI LLC | Director | S Sale | 2025-03-20 | 2025-03-21 | 941 | $54.01 | $50.8K | 487,676 | SEC↗ |
| Ashiya Mona | Director | S Sale | 2025-03-20 | 2025-03-21 | 364 | $54.01 | $19.7K | 188,617 | SEC↗ |
| Ashiya Mona | Director | S Sale | 2025-03-20 | 2025-03-21 | 1,457 | $54.01 | $78.7K | 754,476 | SEC↗ |
| Ashiya Mona | Director | S Sale | 2025-03-20 | 2025-03-21 | 941 | $54.01 | $50.8K | 487,676 | SEC↗ |
| OrbiMed Capital GP VI LLC | Director | S Sale | 2025-03-19 | 2025-03-21 | 5,228 | $54.02 | $282.4K | 188,981 | SEC↗ |