JUNO

Juno Therapeutics, Inc.CIK 1594864 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for JUNO PRO

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AI insights for JUNO

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
LEE ANN L.	EVP, Technical Operations	8	$0	$0	2018-03-05
Azelby Robert	See Remarks	43	$0	$14.06M	2018-03-05
Harr Steve	See Remarks	41	$0	$5.19M	2018-03-05
AGARWAL SUNIL	President of R & D	10	$0	$326.1K	2018-03-05
Klausner Richard	Director	48	$0	$10.49M	2018-03-05
Daniel Thomas O	Director	2	$0	$0	2018-03-05
Bishop Hans Edgar	See Remarks	65	$0	$34.48M	2018-03-05
Barron Hal	Director	18	$2.40M	$0	2018-03-05
Cassidy Bernard J	General Counsel and Secretary	53	$0	$4.52M	2018-03-05
EVNIN ANTHONY B	Director	44	$689.2K	$69.82M	2018-03-05
NELSEN ROBERT	Director, 10% Owner	23	$0	$0	2018-03-05
FLATLEY JAY T	Director	8	$724.4K	$0	2018-03-05
PIEN HOWARD H	Director	21	$0	$0	2018-03-05
Wilderotter Mary Agnes	Director	7	$0	$0	2018-03-05
Crestline Investors, Inc.	10% Owner	2	$0	$551.40M	2017-07-13
Levitsky Hyam	See Remarks	8	$0	$531.1K	2017-02-07
Tessier-Lavigne Marc	Director	4	$0	$0	2016-06-17
ARCH Venture Partners VII, LLC	10% Owner	7	$0	$0	2016-03-15
Frohlich Mark W	See Remarks	4	$0	$705.4K	2016-02-29
BRATTON DOUGLAS K	10% Owner	9	$15.00M	$15.99M	2015-07-02
Crestline SI (GP), L.P.	10% Owner	11	$15.63M	$0	2014-12-23

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
AGARWAL SUNIL	President of R & D	D To issuer deriv	2018-03-05	2018-03-07	313,797	—	$0	0	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	D To issuer deriv	2018-03-05	2018-03-07	98,545	—	$0	0	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	D To issuer deriv	2018-03-05	2018-03-07	93,294	—	$0	0	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	D To issuer deriv	2018-03-05	2018-03-07	30,002	—	$0	0	SEC↗
Barron Hal	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$27.00	$324.0K	0	SEC↗
Barron Hal	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$44.60	$535.2K	0	SEC↗
Barron Hal	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$63.71	$764.5K	0	SEC↗
Barron Hal	Director	D To issuer deriv	2018-03-05	2018-03-07	75,000	$80.64	$6.05M	0	SEC↗
Bishop Hans Edgar	CEO & President	D To issuer deriv	2018-03-05	2018-03-07	140,000	—	$0	0	SEC↗
Bishop Hans Edgar	CEO & President	D To issuer deriv	2018-03-05	2018-03-07	200,000	—	$0	0	SEC↗
Bishop Hans Edgar	CEO & President	D To issuer deriv	2018-03-05	2018-03-07	205,823	—	$0	0	SEC↗
Bishop Hans Edgar	CEO & President	D To issuer deriv	2018-03-05	2018-03-07	451,756	—	$0	0	SEC↗
Cassidy Bernard J	General Counsel & Secretary	D To issuer deriv	2018-03-05	2018-03-07	125,000	—	$0	0	SEC↗
Cassidy Bernard J	General Counsel & Secretary	D To issuer deriv	2018-03-05	2018-03-07	37,500	—	$0	0	SEC↗
Cassidy Bernard J	General Counsel & Secretary	D To issuer deriv	2018-03-05	2018-03-07	75,000	—	$0	0	SEC↗
Cassidy Bernard J	General Counsel & Secretary	D To issuer deriv	2018-03-05	2018-03-07	113,636	—	$0	0	SEC↗
Cassidy Bernard J	General Counsel & Secretary	D To issuer deriv	2018-03-05	2018-03-07	50,500	—	$0	0	SEC↗
Daniel Thomas O	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$63.71	$764.5K	0	SEC↗
EVNIN ANTHONY B	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$27.00	$324.0K	0	SEC↗
EVNIN ANTHONY B	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$63.71	$764.5K	0	SEC↗
EVNIN ANTHONY B	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$44.60	$535.2K	0	SEC↗
FLATLEY JAY T	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$63.71	$764.5K	0	SEC↗
FLATLEY JAY T	Director	D To issuer deriv	2018-03-05	2018-03-07	18,000	$62.93	$1.13M	0	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	D To issuer deriv	2018-03-05	2018-03-07	155,000	—	$0	0	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	D To issuer deriv	2018-03-05	2018-03-07	85,000	—	$0	0	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	D To issuer deriv	2018-03-05	2018-03-07	98,750	—	$0	0	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	D To issuer deriv	2018-03-05	2018-03-07	127,841	—	$0	0	SEC↗
Klausner Richard	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$63.71	$764.5K	0	SEC↗
Klausner Richard	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$44.60	$535.2K	0	SEC↗
Klausner Richard	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$27.00	$324.0K	0	SEC↗
LEE ANN L.	EVP, Technical Operations	D To issuer deriv	2018-03-05	2018-03-07	152,900	—	$0	0	SEC↗
NELSEN ROBERT	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$44.60	$535.2K	0	SEC↗
NELSEN ROBERT	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$63.71	$764.5K	0	SEC↗
NELSEN ROBERT	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$27.00	$324.0K	0	SEC↗
PIEN HOWARD H	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$27.00	$324.0K	0	SEC↗
PIEN HOWARD H	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$44.60	$535.2K	0	SEC↗
PIEN HOWARD H	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$63.71	$764.5K	0	SEC↗
Wilderotter Mary Agnes	Director	D To issuer deriv	2018-03-05	2018-03-07	75,000	$78.28	$5.87M	0	SEC↗
Wilderotter Mary Agnes	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$27.00	$324.0K	0	SEC↗
Wilderotter Mary Agnes	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$63.71	$764.5K	0	SEC↗
Wilderotter Mary Agnes	Director	D To issuer deriv	2018-03-05	2018-03-07	12,000	$44.60	$535.2K	0	SEC↗
AGARWAL SUNIL	President of R & D	D To issuer	2018-03-05	2018-03-07	35,893	—	$0	0	SEC↗
AGARWAL SUNIL	President of R & D	D To issuer	2018-03-05	2018-03-07	84,549	—	$0	65,028	SEC↗
AGARWAL SUNIL	President of R & D	D To issuer	2018-03-05	2018-03-07	29,135	—	$0	35,893	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	D To issuer	2018-03-05	2018-03-07	7,500	—	$0	82,112	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	D To issuer	2018-03-05	2018-03-07	20,580	—	$0	61,532	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	D To issuer	2018-03-05	2018-03-07	25,639	—	$0	35,893	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	D To issuer	2018-03-05	2018-03-07	35,893	—	$0	0	SEC↗
Barron Hal	Director	U Tender	2018-03-05	2018-03-07	100,000	$87.00	$8.70M	3,780	SEC↗
Barron Hal	Director	D To issuer	2018-03-05	2018-03-07	3,780	$87.00	$328.9K	0	SEC↗
Bishop Hans Edgar	CEO & President	D To issuer	2018-03-05	2018-03-07	33,133	—	$0	102,319	SEC↗
Bishop Hans Edgar	CEO & President	D To issuer	2018-03-05	2018-03-07	35,893	—	$0	0	SEC↗
Bishop Hans Edgar	CEO & President	U Tender	2018-03-05	2018-03-07	2,263,948	$87.00	$196.96M	184,281	SEC↗
Bishop Hans Edgar	CEO & President	D To issuer	2018-03-05	2018-03-07	66,426	—	$0	35,893	SEC↗
Bishop Hans Edgar	CEO & President	D To issuer	2018-03-05	2018-03-07	48,829	$87.00	$4.25M	135,452	SEC↗
Cassidy Bernard J	General Counsel & Secretary	U Tender	2018-03-05	2018-03-07	26,869	$87.00	$2.34M	0	SEC↗
Cassidy Bernard J	General Counsel & Secretary	D To issuer	2018-03-05	2018-03-07	35,893	—	$0	0	SEC↗
Cassidy Bernard J	General Counsel & Secretary	D To issuer	2018-03-05	2018-03-07	25,639	—	$0	35,893	SEC↗
Cassidy Bernard J	General Counsel & Secretary	D To issuer	2018-03-05	2018-03-07	18,293	—	$0	61,532	SEC↗
Cassidy Bernard J	General Counsel & Secretary	U Tender	2018-03-05	2018-03-07	5,558	$87.00	$483.5K	79,825	SEC↗
FLATLEY JAY T	Director	U Tender	2018-03-05	2018-03-07	31,500	$87.00	$2.74M	0	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	D To issuer	2018-03-05	2018-03-07	11,544	—	$0	35,893	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	D To issuer	2018-03-05	2018-03-07	29,135	—	$0	47,437	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	U Tender	2018-03-05	2018-03-07	492,355	$87.00	$42.83M	147,162	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	D To issuer	2018-03-05	2018-03-07	50,010	$87.00	$4.35M	97,152	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	D To issuer	2018-03-05	2018-03-07	20,580	—	$0	76,572	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	D To issuer	2018-03-05	2018-03-07	35,893	—	$0	0	SEC↗
Klausner Richard	Director	U Tender	2018-03-05	2018-03-07	705,525	$87.00	$61.38M	0	SEC↗
LEE ANN L.	EVP, Technical Operations	D To issuer	2018-03-05	2018-03-07	35,004	—	$0	75,788	SEC↗
LEE ANN L.	EVP, Technical Operations	D To issuer	2018-03-05	2018-03-07	35,000	—	$0	0	SEC↗
LEE ANN L.	EVP, Technical Operations	D To issuer	2018-03-05	2018-03-07	40,788	—	$0	35,000	SEC↗
NELSEN ROBERT	Director	U Tender	2018-03-05	2018-03-07	50,824	$87.00	$4.42M	3,234	SEC↗
NELSEN ROBERT	Director	D To issuer	2018-03-05	2018-03-07	3,234	$87.00	$281.4K	0	SEC↗
NELSEN ROBERT	Director	U Tender	2018-03-05	2018-03-07	10,552,390	$87.00	$918.06M	0	SEC↗
PIEN HOWARD H	Director	U Tender	2018-03-05	2018-03-07	111,587	$87.00	$9.71M	5,050	SEC↗
PIEN HOWARD H	Director	D To issuer	2018-03-05	2018-03-07	5,050	$87.00	$439.4K	0	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	A Award	2018-02-27	2018-03-01	11,544	—	$0	639,517	SEC↗
EVNIN ANTHONY B	Director	G Gift	2018-02-14	2018-03-07	34,842	—	$0	0	SEC↗
PIEN HOWARD H	Director	G Gift	2018-02-13	2018-03-07	1,162	—	$0	116,637	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	S Sale	2018-02-12	2018-02-14	4,157	$85.55	$355.6K	89,614	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	S Sale	2018-02-12	2018-02-15	4,159	$85.55	$355.8K	89,612	SEC↗
EVNIN ANTHONY B	Director	G Gift	2018-02-09	2018-03-07	25,000	—	$0	34,842	SEC↗
PIEN HOWARD H	Director	G Gift	2018-02-09	2018-03-07	12,251	—	$0	117,799	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise deriv	2018-02-08	2018-02-09	2,663	—	$0	98,545	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise deriv	2018-02-08	2018-02-09	834	—	$0	30,002	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise	2018-02-08	2018-02-09	834	$25.29	$21.1K	94,605	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise	2018-02-08	2018-02-09	2,663	$20.76	$55.3K	97,268	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	S Sale	2018-02-08	2018-02-09	3,497	$85.77	$299.9K	93,771	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	F Tax w/h	2018-02-07	2018-02-09	2,700	$85.49	$230.8K	93,771	SEC↗
Bishop Hans Edgar	CEO & President	G Gift	2018-02-07	2018-02-09	116,280	—	$0	2,448,229	SEC↗
Bishop Hans Edgar	CEO & President	F Tax w/h	2018-02-07	2018-02-09	4,346	$85.49	$371.5K	2,564,509	SEC↗
Cassidy Bernard J	General Counsel & Secretary	G Gift	2018-02-07	2018-02-09	26,634	—	$0	85,262	SEC↗
Cassidy Bernard J	General Counsel & Secretary	F Tax w/h	2018-02-07	2018-02-09	1,528	$85.49	$130.6K	111,896	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	G Gift	2018-02-07	2018-02-09	162,790	—	$0	627,973	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	F Tax w/h	2018-02-07	2018-02-09	1,704	$85.49	$145.7K	790,763	SEC↗
Klausner Richard	Director	G Gift	2018-02-07	2018-03-07	23,250	—	$0	705,525	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise deriv	2018-02-01	2018-02-02	4,167	—	$0	93,294	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise	2018-02-01	2018-02-02	4,167	$51.76	$215.7K	100,638	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	S Sale	2018-02-01	2018-02-02	4,167	$85.78	$357.4K	96,471	SEC↗
AGARWAL SUNIL	President of R & D	A Award	2018-01-31	2018-02-02	29,135	—	$0	149,577	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	A Award	2018-01-31	2018-02-02	25,639	—	$0	96,471	SEC↗
Bishop Hans Edgar	CEO & President	A Award	2018-01-31	2018-02-02	66,426	—	$0	2,568,855	SEC↗
Cassidy Bernard J	General Counsel & Secretary	A Award	2018-01-31	2018-02-02	25,639	—	$0	113,424	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	A Award	2018-01-31	2018-02-02	29,135	—	$0	792,467	SEC↗
LEE ANN L.	EVP, Technical Operations	A Award	2018-01-31	2018-02-02	40,788	—	$0	110,792	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise deriv	2018-01-22	2018-01-24	102,539	—	$0	97,461	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise	2018-01-22	2018-01-24	102,539	$51.76	$5.31M	173,371	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	S Sale	2018-01-22	2018-01-24	102,539	$86.25	$8.84M	70,832	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise deriv	2018-01-17	2018-01-19	26,633	—	$0	101,208	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise deriv	2018-01-17	2018-01-19	2,498	—	$0	30,836	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise	2018-01-17	2018-01-19	2,498	$25.29	$63.2K	73,330	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	S Sale	2018-01-17	2018-01-19	7,990	$69.95	$558.9K	70,832	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	S Sale	2018-01-17	2018-01-19	21,141	$68.10	$1.44M	78,822	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise	2018-01-17	2018-01-19	26,633	$20.76	$552.9K	99,963	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise deriv	2018-01-16	2018-01-18	245,750	—	$0	451,756	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2018-01-16	2018-01-18	65,820	$44.72	$2.94M	2,706,859	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise	2018-01-16	2018-01-18	245,750	$6.36	$1.56M	2,772,679	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2018-01-16	2018-01-18	89,888	$45.53	$4.09M	2,616,971	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2018-01-16	2018-01-18	49,082	$46.52	$2.28M	2,567,889	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2018-01-16	2018-01-18	23,003	$47.69	$1.10M	2,544,886	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2018-01-16	2018-01-18	42,457	$48.56	$2.06M	2,502,429	SEC↗
Klausner Richard	Director	S Sale	2018-01-08	2018-01-09	918	$49.37	$45.3K	728,775	SEC↗
Klausner Richard	Director	S Sale	2018-01-08	2018-01-09	4,846	$48.95	$237.2K	729,693	SEC↗
Klausner Richard	Director	S Sale	2018-01-08	2018-01-09	5,011	$47.80	$239.5K	734,539	SEC↗
Klausner Richard	Director	S Sale	2018-01-08	2018-01-09	1,949	$46.85	$91.3K	739,550	SEC↗
Barron Hal	Director	A Award	2018-01-05	2018-01-09	336	—	$0	103,780	SEC↗
EVNIN ANTHONY B	Director	A Award	2018-01-05	2018-01-09	150	—	$0	59,842	SEC↗
Klausner Richard	Director	A Award	2018-01-05	2018-01-09	248	—	$0	741,499	SEC↗
NELSEN ROBERT	Director	A Award	2018-01-05	2018-01-09	237	—	$0	54,058	SEC↗
PIEN HOWARD H	Director	A Award	2018-01-05	2018-01-09	417	—	$0	130,050	SEC↗
PIEN HOWARD H	Director	G Gift	2017-12-22	2018-01-09	25,000	—	$0	129,633	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	M Exercise deriv	2017-12-21	2017-12-22	8,750	—	$0	98,750	SEC↗
Klausner Richard	Director	S Sale	2017-12-21	2017-12-22	3,141	$45.16	$141.8K	741,251	SEC↗
Klausner Richard	Director	S Sale	2017-12-21	2017-12-22	32,859	$44.72	$1.47M	744,392	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	M Exercise	2017-12-21	2017-12-22	8,750	$8.72	$76.3K	772,082	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	S Sale	2017-12-21	2017-12-22	500	$45.18	$22.6K	763,332	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	S Sale	2017-12-21	2017-12-22	8,250	$44.74	$369.1K	763,832	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	S Sale	2017-12-18	2017-12-20	1,816	$44.96	$81.6K	70,832	SEC↗
LEE ANN L.	EVP, Technical Operations	A Award deriv	2017-11-25	2017-11-28	152,900	—	$0	152,900	SEC↗
LEE ANN L.	EVP, Technical Operations	A Award	2017-11-25	2017-11-28	35,000	—	$0	70,004	SEC↗
LEE ANN L.	EVP, Technical Operations	A Award	2017-11-25	2017-11-28	35,004	—	$0	35,004	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	F Tax w/h	2017-11-08	2017-11-09	684	$55.98	$38.3K	72,648	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise deriv	2017-11-02	2017-11-03	6,666	—	$0	33,334	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	M Exercise	2017-11-02	2017-11-03	6,666	$25.29	$168.6K	79,998	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	S Sale	2017-11-02	2017-11-03	6,666	$54.95	$366.3K	73,332	SEC↗
AGARWAL SUNIL	President of R & D	A Award	2017-10-20	2017-10-20	35,893	—	$0	120,442	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	A Award	2017-10-20	2017-10-20	35,893	—	$0	73,332	SEC↗
Bishop Hans Edgar	CEO & President	A Award	2017-10-20	2017-10-20	35,893	—	$0	2,526,929	SEC↗
Cassidy Bernard J	General Counsel & Secretary	A Award	2017-10-20	2017-10-20	35,893	—	$0	86,917	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	A Award	2017-10-20	2017-10-20	35,893	—	$0	763,332	SEC↗
Barron Hal	Director	A Award	2017-10-05	2017-10-06	361	—	$0	103,444	SEC↗
EVNIN ANTHONY B	Director	A Award	2017-10-05	2017-10-06	161	—	$0	59,692	SEC↗
Klausner Richard	Director	A Award	2017-10-05	2017-10-06	266	—	$0	777,251	SEC↗
PIEN HOWARD H	Director	A Award	2017-10-05	2017-10-06	447	—	$0	154,633	SEC↗
NELSEN ROBERT	Director	A Award	2017-10-05	2017-10-10	254	—	$0	53,821	SEC↗
AGARWAL SUNIL	President of R & D	S Sale	2017-10-02	2017-10-04	7,285	$44.76	$326.1K	84,549	SEC↗
Cassidy Bernard J	General Counsel & Secretary	S Sale	2017-09-14	2017-09-14	3,441	$45.90	$157.9K	52,529	SEC↗
Cassidy Bernard J	General Counsel & Secretary	S Sale	2017-09-14	2017-09-14	1,505	$46.58	$70.1K	51,024	SEC↗
Cassidy Bernard J	General Counsel & Secretary	S Sale	2017-09-14	2017-09-14	23,054	$44.67	$1.03M	55,970	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	S Sale	2017-09-13	2017-09-14	12,850	$44.95	$577.6K	37,439	SEC↗
Klausner Richard	Director	S Sale	2017-09-07	2017-09-08	1,337	$43.83	$58.6K	776,985	SEC↗
Klausner Richard	Director	S Sale	2017-09-07	2017-09-08	5,214	$42.76	$223.0K	778,322	SEC↗
Klausner Richard	Director	S Sale	2017-09-07	2017-09-08	5,449	$42.27	$230.3K	783,536	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	S Sale	2017-08-29	2017-08-31	12,869	$39.95	$514.1K	50,289	SEC↗
Klausner Richard	Director	S Sale	2017-08-07	2017-08-09	12,000	$30.34	$364.1K	788,985	SEC↗
Crestline Investors, Inc.	10% Owner	S Sale	2017-07-13	2017-07-17	8,000,000	$27.00	$216.00M	9,166,130	SEC↗
Klausner Richard	Director	S Sale	2017-07-07	2017-07-07	23,600	$29.38	$693.4K	801,385	SEC↗
Klausner Richard	Director	S Sale	2017-07-07	2017-07-07	400	$30.00	$12.0K	800,985	SEC↗
EVNIN ANTHONY B	Director	G Gift	2017-07-06	2017-07-07	7,000	—	$0	59,531	SEC↗
Barron Hal	Director	A Award	2017-07-05	2017-07-07	516	—	$0	103,083	SEC↗
EVNIN ANTHONY B	Director	A Award	2017-07-05	2017-07-07	230	—	$0	66,531	SEC↗
Klausner Richard	Director	A Award	2017-07-05	2017-07-07	380	—	$0	824,985	SEC↗
NELSEN ROBERT	Director, 10% Owner	A Award	2017-07-05	2017-07-07	400	—	$0	53,567	SEC↗
PIEN HOWARD H	Director	A Award	2017-07-05	2017-07-07	640	—	$0	154,186	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	M Exercise deriv	2017-07-03	2017-07-05	8,750	—	$0	107,500	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	S Sale	2017-07-03	2017-07-05	8,750	$30.00	$262.5K	727,439	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	M Exercise	2017-07-03	2017-07-05	8,750	$8.72	$76.3K	736,189	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	M Exercise deriv	2017-06-27	2017-06-29	8,750	—	$0	116,250	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	M Exercise	2017-06-27	2017-06-29	8,750	$8.72	$76.3K	736,189	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	S Sale	2017-06-27	2017-06-29	8,750	$30.00	$262.5K	727,439	SEC↗
EVNIN ANTHONY B	Director	P Buy	2017-06-20	2017-06-21	9,000	$24.40	$219.6K	66,301	SEC↗
Barron Hal	Director	A Award deriv	2017-06-16	2017-06-19	12,000	—	$0	12,000	SEC↗
Daniel Thomas O	Director	A Award deriv	2017-06-16	2017-06-19	12,000	—	$0	12,000	SEC↗
EVNIN ANTHONY B	Director	A Award deriv	2017-06-16	2017-06-19	12,000	—	$0	12,000	SEC↗
FLATLEY JAY T	Director	A Award deriv	2017-06-16	2017-06-19	12,000	—	$0	12,000	SEC↗
Klausner Richard	Director	A Award deriv	2017-06-16	2017-06-19	12,000	—	$0	12,000	SEC↗
NELSEN ROBERT	Director, 10% Owner	A Award deriv	2017-06-16	2017-06-19	12,000	—	$0	12,000	SEC↗
PIEN HOWARD H	Director	A Award deriv	2017-06-16	2017-06-19	12,000	—	$0	12,000	SEC↗
Wilderotter Mary Agnes	Director	A Award deriv	2017-06-16	2017-06-19	12,000	—	$0	12,000	SEC↗
Klausner Richard	Director	S Sale	2017-06-07	2017-06-09	8,768	$24.24	$212.5K	824,605	SEC↗
Klausner Richard	Director	S Sale	2017-06-07	2017-06-09	15,232	$23.23	$353.8K	833,373	SEC↗
FLATLEY JAY T	Director	P Buy	2017-05-30	2018-01-30	10,000	$22.92	$229.2K	31,500	SEC↗
FLATLEY JAY T	Director	P Buy	2017-05-26	2017-05-26	10,000	$24.37	$243.7K	21,500	SEC↗
FLATLEY JAY T	Director	P Buy	2017-05-24	2017-05-26	10,000	$25.15	$251.5K	11,500	SEC↗
FLATLEY JAY T	Director	A Award deriv	2017-05-22	2017-05-23	18,000	—	$0	18,000	SEC↗
AGARWAL SUNIL	President of R & D	A Award deriv	2017-04-13	2017-04-17	313,797	—	$0	313,797	SEC↗
AGARWAL SUNIL	President of R & D	F Tax w/h	2017-04-13	2017-04-17	4,793	$24.01	$115.1K	91,834	SEC↗
AGARWAL SUNIL	President of R & D	A Award	2017-04-13	2017-04-17	96,627	—	$0	96,627	SEC↗
Barron Hal	Director	A Award	2017-04-05	2017-04-06	698	—	$0	102,567	SEC↗
EVNIN ANTHONY B	Director	A Award	2017-04-05	2017-04-06	311	—	$0	57,301	SEC↗
Klausner Richard	Director	A Award	2017-04-05	2017-04-06	514	—	$0	848,605	SEC↗
NELSEN ROBERT	Director, 10% Owner	A Award	2017-04-05	2017-04-06	573	—	$0	53,167	SEC↗
PIEN HOWARD H	Director	A Award	2017-04-05	2017-04-06	865	—	$0	153,546	SEC↗
EVNIN ANTHONY B	Director	P Buy	2017-03-10	2017-03-13	8,000	$22.11	$176.9K	56,990	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	A Award deriv	2017-02-07	2017-02-09	127,841	—	$0	127,841	SEC↗
Bishop Hans Edgar	CEO & President	A Award deriv	2017-02-07	2017-02-09	205,823	—	$0	205,823	SEC↗
Cassidy Bernard J	General Counsel & Secretary	A Award deriv	2017-02-07	2017-02-09	113,636	—	$0	113,636	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	A Award deriv	2017-02-07	2017-02-09	127,841	—	$0	127,841	SEC↗
Levitsky Hyam	EVP, Research & CSO	A Award deriv	2017-02-07	2017-02-09	68,182	—	$0	68,182	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	A Award	2017-02-07	2017-02-09	27,439	—	$0	63,158	SEC↗
Bishop Hans Edgar	CEO & President	A Award	2017-02-07	2017-02-09	44,177	—	$0	2,491,036	SEC↗
Cassidy Bernard J	General Counsel & Secretary	A Award	2017-02-07	2017-02-09	24,390	—	$0	79,024	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	A Award	2017-02-07	2017-02-09	27,439	—	$0	727,439	SEC↗
Levitsky Hyam	EVP, Research & CSO	A Award	2017-02-07	2017-02-09	14,634	—	$0	131,334	SEC↗
Barron Hal	Director	A Award	2017-01-05	2017-01-09	768	—	$0	101,869	SEC↗
EVNIN ANTHONY B	Director	A Award	2017-01-05	2017-01-09	715	—	$0	48,990	SEC↗
Klausner Richard	Director	A Award	2017-01-05	2017-01-09	591	—	$0	848,091	SEC↗
PIEN HOWARD H	Director	A Award	2017-01-05	2017-01-09	995	—	$0	152,681	SEC↗
NELSEN ROBERT	Director, 10% Owner	A Award	2017-01-05	2017-01-09	659	—	$0	52,594	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	S Sale	2016-11-10	2016-11-10	12,921	$24.14	$311.9K	35,719	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	A Award deriv	2016-11-08	2016-11-10	40,000	—	$0	40,000	SEC↗
Azelby Robert	EVP & Chief Commercial Offic	A Award	2016-11-08	2016-11-10	10,000	—	$0	48,640	SEC↗
Barron Hal	Director	A Award	2016-10-05	2016-10-17	438	—	$0	101,101	SEC↗
NELSEN ROBERT	Director, 10% Owner	A Award	2016-10-05	2016-10-17	447	—	$0	51,935	SEC↗
EVNIN ANTHONY B	Director	A Award	2016-10-05	2016-10-17	485	—	$0	48,275	SEC↗
PIEN HOWARD H	Director	A Award	2016-10-05	2016-10-17	675	—	$0	151,686	SEC↗
Klausner Richard	Director	A Award	2016-10-05	2016-10-17	401	—	$0	847,500	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise deriv	2016-09-27	2016-09-29	44,000	—	$0	697,506	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise	2016-09-27	2016-09-29	44,000	$6.36	$279.8K	2,490,859	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2016-09-27	2016-09-29	44,000	$33.00	$1.45M	2,446,859	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise deriv	2016-09-21	2016-09-21	6,057	—	$0	741,506	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise	2016-09-21	2016-09-21	6,057	$6.36	$38.5K	2,524,166	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2016-09-21	2016-09-21	77,307	$30.30	$2.34M	2,446,859	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise deriv	2016-09-20	2016-09-21	6,300	—	$0	747,563	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2016-09-20	2016-09-21	6,300	$30.00	$189.0K	2,518,109	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise	2016-09-20	2016-09-21	6,300	$6.36	$40.1K	2,524,409	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise deriv	2016-09-19	2016-09-21	428	—	$0	753,863	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2016-09-19	2016-09-21	428	$30.00	$12.8K	2,518,109	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise	2016-09-19	2016-09-21	428	$6.36	$2.7K	2,518,537	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise deriv	2016-09-08	2016-09-09	23,042	—	$0	754,291	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2016-09-08	2016-09-09	23,042	$30.06	$692.6K	2,518,109	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise	2016-09-08	2016-09-09	23,042	$6.36	$146.5K	2,541,151	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise deriv	2016-08-31	2016-09-02	18,173	—	$0	777,333	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise	2016-08-31	2016-09-02	18,173	$6.36	$115.6K	2,560,782	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2016-08-31	2016-09-02	42,673	$30.06	$1.28M	2,518,109	SEC↗
EVNIN ANTHONY B	Director	G Gift	2016-08-23	2016-08-25	10,937	—	$0	47,790	SEC↗
Barron Hal	Director	A Award	2016-07-05	2016-07-05	328	—	$0	100,663	SEC↗
PIEN HOWARD H	Director	A Award	2016-07-05	2016-07-05	505	—	$0	151,011	SEC↗
EVNIN ANTHONY B	Director	A Award	2016-07-05	2016-07-05	363	—	$0	58,727	SEC↗
Klausner Richard	Director	A Award	2016-07-05	2016-07-05	300	—	$0	847,099	SEC↗
NELSEN ROBERT	Director, 10% Owner	A Award	2016-07-05	2016-07-05	335	—	$0	51,488	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise deriv	2016-06-30	2016-07-01	44,000	—	$0	795,506	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise deriv	2016-06-30	2016-09-02	44,000	—	$0	795,506	SEC↗
Bishop Hans Edgar	CEO & President	D To issuer	2016-06-30	2016-07-01	108,894	$38.41	$4.18M	2,548,965	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise	2016-06-30	2016-07-01	44,000	$6.36	$279.8K	2,657,859	SEC↗
Bishop Hans Edgar	CEO & President	D To issuer	2016-06-30	2016-07-01	6,356	$39.18	$249.0K	2,542,609	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2016-06-30	2016-09-02	108,894	$38.41	$4.18M	2,548,965	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise	2016-06-30	2016-09-02	44,000	$6.36	$279.8K	2,657,859	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2016-06-30	2016-09-02	6,356	$39.18	$249.0K	2,542,609	SEC↗
Klausner Richard	Director	S Sale	2016-06-24	2016-06-24	12,000	$40.71	$488.5K	846,799	SEC↗
Barron Hal	Director	A Award deriv	2016-06-17	2016-06-21	12,000	—	$0	12,000	SEC↗
EVNIN ANTHONY B	Director	A Award deriv	2016-06-17	2016-06-21	12,000	—	$0	12,000	SEC↗
Klausner Richard	Director	A Award deriv	2016-06-17	2016-06-21	12,000	—	$0	12,000	SEC↗
NELSEN ROBERT	Director, 10% Owner	A Award deriv	2016-06-17	2016-06-21	12,000	—	$0	12,000	SEC↗
PIEN HOWARD H	Director	A Award deriv	2016-06-17	2016-06-21	12,000	—	$0	12,000	SEC↗
Tessier-Lavigne Marc	Director	A Award deriv	2016-06-17	2016-06-21	12,000	—	$0	12,000	SEC↗
Wilderotter Mary Agnes	Director	A Award deriv	2016-06-17	2016-06-21	12,000	—	$0	12,000	SEC↗
Levitsky Hyam	EVP, Research & CSO	S Sale	2016-06-17	2016-06-21	300	$43.20	$13.0K	116,700	SEC↗
Levitsky Hyam	EVP, Research & CSO	S Sale	2016-06-17	2016-06-21	12,118	$42.76	$518.2K	117,000	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	S Sale	2016-06-10	2016-06-13	16,052	$43.69	$701.3K	700,000	SEC↗
Harr Steve	CFO & Head, Corp. Developmen	S Sale	2016-06-10	2016-06-13	13,948	$42.89	$598.2K	716,052	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise deriv	2016-06-09	2016-06-13	54,000	—	$0	839,506	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2016-06-09	2016-06-13	59,675	$45.80	$2.73M	2,644,934	SEC↗
Bishop Hans Edgar	CEO & President	M Exercise	2016-06-09	2016-06-13	54,000	$6.36	$343.4K	2,704,609	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2016-06-09	2016-06-13	16,751	$47.03	$787.8K	2,628,183	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2016-06-09	2016-06-13	8,394	$47.97	$402.7K	2,619,789	SEC↗
Bishop Hans Edgar	CEO & President	S Sale	2016-06-09	2016-06-13	5,930	$48.74	$289.0K	2,613,859	SEC↗
Levitsky Hyam	EVP, Research & CSO	F Tax w/h	2016-05-27	2016-05-27	16,454	$42.04	$691.7K	129,118	SEC↗
Cassidy Bernard J	General Counsel & Secretary	S Sale	2016-05-19	2016-05-20	877	$39.69	$34.8K	54,634	SEC↗
Cassidy Bernard J	General Counsel & Secretary	S Sale	2016-05-19	2016-05-20	2,239	$38.77	$86.8K	55,511	SEC↗
Klausner Richard	Director	S Sale	2016-05-18	2016-05-20	12,000	$40.00	$480.0K	858,799	SEC↗
Cassidy Bernard J	General Counsel & Secretary	S Sale	2016-04-19	2016-04-19	650	$43.60	$28.3K	57,283	SEC↗
Cassidy Bernard J	General Counsel & Secretary	S Sale	2016-04-19	2016-04-19	2,550	$43.00	$109.7K	57,933	SEC↗
Klausner Richard	Director	S Sale	2016-04-15	2016-04-19	1,993	$43.51	$86.7K	870,799	SEC↗
Klausner Richard	Director	S Sale	2016-04-15	2016-04-19	10,007	$42.79	$428.2K	872,792	SEC↗
Barron Hal	Director	A Award	2016-04-05	2016-04-07	335	—	$0	100,335	SEC↗
EVNIN ANTHONY B	Director	A Award	2016-04-05	2016-04-07	364	—	$0	58,364	SEC↗
Klausner Richard	Director	A Award	2016-04-05	2016-04-07	300	—	$0	882,799	SEC↗
NELSEN ROBERT	Director, 10% Owner	A Award	2016-04-05	2016-04-07	329	—	$0	51,153	SEC↗
PIEN HOWARD H	Director	A Award	2016-04-05	2016-04-07	506	—	$0	150,506	SEC↗
EVNIN ANTHONY B	Director	P Buy	2016-03-28	2016-03-30	3,946	$36.22	$142.9K	53,946	SEC↗
EVNIN ANTHONY B	Director	P Buy	2016-03-28	2016-03-30	4,054	$36.94	$149.8K	58,000	SEC↗
Klausner Richard	Director	S Sale	2016-03-22	2016-03-22	12,000	$40.00	$480.0K	882,499	SEC↗
Cassidy Bernard J	General Counsel & Secretary	S Sale	2016-03-18	2016-03-18	1,818	$37.96	$69.0K	61,865	SEC↗
Cassidy Bernard J	General Counsel & Secretary	S Sale	2016-03-18	2016-03-18	1,382	$38.47	$53.2K	60,483	SEC↗
EVNIN ANTHONY B	Director	G Gift	2016-03-17	2016-03-30	15,000	—	$0	50,000	SEC↗
ARCH Venture Partners VII, LLC	10% Owner	J Other	2016-03-15	2016-03-17	1,000,000	—	$0	10,552,390	SEC↗
Harr Steve	See Remarks	S Sale	2016-03-04	2016-03-04	5,000	$45.00	$225.0K	730,000	SEC↗
Klausner Richard	Director	S Sale	2016-03-02	2016-03-02	23,240	$40.39	$938.7K	895,259	SEC↗
Klausner Richard	Director	S Sale	2016-03-02	2016-03-02	760	$41.22	$31.3K	894,499	SEC↗