KROS

Keros Therapeutics, Inc.CIK 1664710 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

$20.5K

2 trades · 1 insiders

Open-mkt sales · 90d

$202.3K

8 trades · 4 insiders

Net · 90d

$-181.7K

Insiders on file

AI insights for KROS PRO

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AI insights for KROS

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date

Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Tanini Annita	Corp. Controller & VP, Finance	2	$0	$25.2K	2026-08-18
Cho Esther	SVP, General Counsel	5	$0	$169.9K	2026-08-18
Lerner Lorena Raquel	Chief Scientific Officer	4	$0	$136.8K	2026-08-18
Newton Charles W.	Director	5	$0	$16.9K	2026-08-18
BIENAIME JEAN JACQUES	Director	12	$86.0K	$0	2026-08-17
Prener Anne	Director	2	$0	$0	2026-07-01
Knowles Julius	Director	280	$25.0K	$28.79M	2026-06-04
Farzan Nima	Director	10	$0	$28.2K	2026-06-04
Seth Alpna	Director	8	$0	$28.1K	2026-06-04
GRAY MARY ANN	Director	9	$0	$0	2026-06-03
Seehra Jasbir	Chief Executive Officer	22	$320.0K	$113.4K	2026-04-02
Regnante Keith	Chief Financial Officer	23	$0	$5.56M	2026-02-24
OrbiMed Genesis GP LLC	Director	4	$0	$11.00M	2025-11-21
GORDON CARL L	Director	15	$6.00M	$11.00M	2025-11-21
Schneeberger Daniel	10% Owner	9	$0	$95.66M	2025-10-15
Pontifax (China) IV L.P.	10% Owner	8	$3.00M	$84.98M	2025-10-15
Nussbaum Ran	Director, 10% Owner	38	$7.00M	$0	2025-06-04
Kariv Tomer	Director, 10% Owner	38	$7.00M	$0	2025-06-04
ADAR1 Capital Management, LLC	10% Owner	3	$0	$0	2025-05-16
ADAR1 Partners, LP	10% Owner	8	$9.47M	$0	2025-04-09
CHYUNG YUNG H.	Chief Medical Officer	2	$0	$0	2025-02-18
Rovaldi Christopher	Chief Operating Officer	14	$0	$162.0K	2025-02-18
Cooper Simon Peter	Chief Medical Officer	4	$0	$0	2024-02-13
Pontifax Late Stage GP Ltd.	10% Owner	6	$0	$0	2022-11-29
Lachey Jennifer	Chief Scientific Officer	102	$0	$6.26M	2022-07-15
Ordonez Claudia	Chief Medical Officer	25	$0	$290.5K	2021-06-11
Pontifax Late Stage Fund L.P.	10% Owner	30	$10.00M	$0	2020-11-17
Pontifax (Israel) IV, L.P.	10% Owner	4	$3.00M	$0	2020-11-17
Arkin Bio Venture Partners Ltd.	10% Owner	7	$1.92M	$0	2020-04-13
Lazarus Alon	Director, 10% Owner	7	$1.92M	$0	2020-04-13
OrbiMed Capital GP VII LLC	Director	5	$6.00M	$0	2020-04-13

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Newton Charles W.	Director	S Sale	2026-08-18	2026-08-20	551	$10.30	$5.7K	12,114	SEC↗
Cho Esther	Chief Legal Officer	S Sale	2026-08-18	2026-08-20	4,485	$10.29	$46.2K	35,770	SEC↗
Lerner Lorena Raquel	Chief Scientific Officer	S Sale	2026-08-18	2026-08-20	3,568	$10.29	$36.7K	27,559	SEC↗
Tanini Annita	Corp. Controller & VP, Finan	S Sale	2026-08-18	2026-08-20	1,224	$10.29	$12.6K	45,144	SEC↗
Tanini Annita	Corp. Controller & VP, Finan	S Sale	2026-08-18	2026-08-20	1,224	$10.29	$12.6K	45,144	SEC↗
Lerner Lorena Raquel	Chief Scientific Officer	S Sale	2026-08-18	2026-08-20	3,568	$10.29	$36.7K	27,559	SEC↗
Newton Charles W.	Director	S Sale	2026-08-18	2026-08-20	551	$10.30	$5.7K	12,114	SEC↗
Cho Esther	Chief Legal Officer	S Sale	2026-08-18	2026-08-20	4,485	$10.29	$46.2K	35,770	SEC↗
BIENAIME JEAN JACQUES	Director	P Buy	2026-08-17	2026-08-19	1,000	$10.27	$10.3K	19,592	SEC↗
BIENAIME JEAN JACQUES	Director	P Buy	2026-08-17	2026-08-19	1,000	$10.27	$10.3K	19,592	SEC↗
BIENAIME JEAN JACQUES	Director	P Buy	2026-07-15	2026-07-17	1,000	$10.61	$10.6K	18,592	SEC↗
Prener Anne	Director	A Award deriv	2026-07-01	2026-07-06	14,870	—	$0	14,870	SEC↗
Prener Anne	Director	A Award	2026-07-01	2026-07-06	13,786	—	$0	13,786	SEC↗
BIENAIME JEAN JACQUES	Director	P Buy	2026-06-15	2026-06-17	1,000	$10.19	$10.2K	17,592	SEC↗
Newton Charles W.	Director	S Sale	2026-06-11	2026-06-15	550	$10.04	$5.5K	12,665	SEC↗
Seth Alpna	Director	S Sale	2026-06-04	2026-06-05	2,625	$10.72	$28.1K	9,767	SEC↗
Knowles Julius	Director	S Sale	2026-06-04	2026-06-08	2,625	$10.73	$28.2K	10,958	SEC↗
Farzan Nima	Director	S Sale	2026-06-04	2026-06-08	2,625	$10.73	$28.2K	9,767	SEC↗
BIENAIME JEAN JACQUES	Director	A Award deriv	2026-06-03	2026-06-05	7,433	—	$0	7,433	SEC↗
Farzan Nima	Director	A Award deriv	2026-06-03	2026-06-05	7,433	—	$0	7,433	SEC↗
GRAY MARY ANN	Director	A Award deriv	2026-06-03	2026-06-05	7,433	—	$0	7,433	SEC↗
Knowles Julius	Director	A Award deriv	2026-06-03	2026-06-05	7,433	—	$0	7,433	SEC↗
Seth Alpna	Director	A Award deriv	2026-06-03	2026-06-05	7,433	—	$0	7,433	SEC↗
BIENAIME JEAN JACQUES	Director	A Award	2026-06-03	2026-06-05	7,142	—	$0	16,592	SEC↗
Farzan Nima	Director	A Award	2026-06-03	2026-06-05	7,142	—	$0	12,392	SEC↗
GRAY MARY ANN	Director	A Award	2026-06-03	2026-06-05	7,142	—	$0	12,392	SEC↗
Knowles Julius	Director	A Award	2026-06-03	2026-06-05	7,142	—	$0	13,583	SEC↗
Seth Alpna	Director	A Award	2026-06-03	2026-06-05	7,142	—	$0	12,392	SEC↗
BIENAIME JEAN JACQUES	Director	P Buy	2026-05-15	2026-05-19	1,000	$10.58	$10.6K	9,450	SEC↗
BIENAIME JEAN JACQUES	Director	P Buy	2026-04-15	2026-04-17	1,000	$11.70	$11.7K	8,450	SEC↗
Seehra Jasbir	CHIEF EXECUTIVE OFFICER	M Exercise deriv	2026-04-02	2026-04-06	55,000	—	$0	197,444	SEC↗
Seehra Jasbir	CHIEF EXECUTIVE OFFICER	M Exercise	2026-04-02	2026-04-06	55,000	$0.30	$16.5K	440,708	SEC↗
Newton Charles W.	Director	A Award deriv	2026-03-09	2026-03-11	14,788	—	$0	14,788	SEC↗
BIENAIME JEAN JACQUES	Director	P Buy	2026-03-09	2026-03-11	2,000	$11.21	$22.4K	7,450	SEC↗
Newton Charles W.	Director	A Award	2026-03-09	2026-03-11	13,215	—	$0	13,215	SEC↗
Lerner Lorena Raquel	Chief Scientific Officer	A Award deriv	2026-02-24	2026-02-26	75,000	—	$0	75,000	SEC↗
Cho Esther	Chief Legal Officer	A Award deriv	2026-02-24	2026-02-26	80,000	—	$0	80,000	SEC↗
Regnante Keith	CHIEF FINANCIAL OFFICER	A Award deriv	2026-02-24	2026-02-26	60,000	—	$0	60,000	SEC↗
Seehra Jasbir	CHIEF EXECUTIVE OFFICER	A Award deriv	2026-02-24	2026-02-26	100,000	—	$0	100,000	SEC↗
Seehra Jasbir	CHIEF EXECUTIVE OFFICER	A Award deriv	2026-02-24	2026-02-26	217,000	—	$0	217,000	SEC↗
Cho Esther	Chief Legal Officer	A Award deriv	2026-02-24	2026-03-27	80,000	—	$0	80,000	SEC↗
Seehra Jasbir	CHIEF EXECUTIVE OFFICER	S Sale	2026-02-19	2026-02-20	7,015	$16.17	$113.4K	385,708	SEC↗
Regnante Keith	CHIEF FINANCIAL OFFICER	S Sale	2026-02-18	2026-02-20	4,739	$16.35	$77.5K	39,261	SEC↗
Cho Esther	SVP, General Counsel	S Sale	2026-02-18	2026-02-20	4,745	$16.35	$77.6K	39,755	SEC↗
Lerner Lorena Raquel	Chief Science Officer	S Sale	2026-02-18	2026-02-20	3,873	$16.35	$63.3K	31,127	SEC↗
Seehra Jasbir	CHIEF EXECUTIVE OFFICER	A Award deriv	2026-01-07	2026-01-09	62,500	—	$0	62,500	SEC↗
Knowles Julius	Director	D To issuer	2025-11-21	2025-12-18	130,494	$17.75	$2.32M	102,233	SEC↗
Knowles Julius	Director	D To issuer	2025-11-21	2025-12-18	191,527	$17.75	$3.40M	150,047	SEC↗
GORDON CARL L	Director	D To issuer	2025-11-21	2025-12-18	140,057	$17.75	$2.49M	759,155	SEC↗
GORDON CARL L	Director	D To issuer	2025-11-21	2025-12-18	74,465	$17.75	$1.32M	45,057	SEC↗
OrbiMed Genesis GP LLC	Director	D To issuer	2025-11-21	2025-12-18	74,465	$17.75	$1.32M	45,057	SEC↗
OrbiMed Genesis GP LLC	Director	D To issuer	2025-11-21	2025-12-18	140,057	$17.75	$2.49M	759,155	SEC↗
Schneeberger Daniel	10% Owner	S Sale	2025-10-15	2025-10-15	743,358	$17.75	$13.19M	0	SEC↗
Schneeberger Daniel	10% Owner	S Sale	2025-10-15	2025-10-15	4,391,237	$17.75	$77.94M	0	SEC↗
Schneeberger Daniel	10% Owner	S Sale	2025-10-15	2025-10-15	254,669	$17.75	$4.52M	0	SEC↗
Pontifax (China) IV L.P.	10% Owner	S Sale	2025-10-15	2025-10-17	1,121,045	$17.75	$19.90M	0	SEC↗
Pontifax (China) IV L.P.	10% Owner	S Sale	2025-10-15	2025-10-17	1,226,412	$17.75	$21.77M	0	SEC↗
Pontifax (China) IV L.P.	10% Owner	S Sale	2025-10-15	2025-10-17	155,262	$17.75	$2.76M	0	SEC↗
Pontifax (China) IV L.P.	10% Owner	S Sale	2025-10-15	2025-10-17	2,284,612	$17.75	$40.55M	0	SEC↗
Seehra Jasbir	CHIEF EXECUTIVE OFFICER	A Award	2025-09-03	2025-09-05	90,500	—	$0	392,723	SEC↗
Schneeberger Daniel	10% Owner	X Exercise deriv	2025-06-20	2025-06-24	2	—	$0	0	SEC↗
Schneeberger Daniel	10% Owner	X Exercise deriv	2025-06-20	2025-06-24	14	—	$0	0	SEC↗
Schneeberger Daniel	10% Owner	X Exercise deriv	2025-06-20	2025-06-24	1	—	$0	0	SEC↗
Schneeberger Daniel	10% Owner	X Exercise	2025-06-20	2025-06-24	200	$70.00	$14.0K	743,358	SEC↗
Schneeberger Daniel	10% Owner	X Exercise	2025-06-20	2025-06-24	100	$60.00	$6.0K	4,392,637	SEC↗
Schneeberger Daniel	10% Owner	X Exercise	2025-06-20	2025-06-24	1,400	$70.00	$98.0K	4,391,237	SEC↗
BIENAIME JEAN JACQUES	Director	A Award deriv	2025-06-04	2025-06-06	10,500	—	$0	10,500	SEC↗
Farzan Nima	Director	A Award deriv	2025-06-04	2025-06-06	10,500	—	$0	10,500	SEC↗
GRAY MARY ANN	Director	A Award deriv	2025-06-04	2025-06-06	10,500	—	$0	10,500	SEC↗
Seth Alpna	Director	A Award deriv	2025-06-04	2025-06-06	10,500	—	$0	10,500	SEC↗
Nussbaum Ran	Director, 10% Owner	A Award deriv	2025-06-04	2025-06-06	10,500	—	$0	10,500	SEC↗
Kariv Tomer	Director, 10% Owner	A Award deriv	2025-06-04	2025-06-06	10,500	—	$0	10,500	SEC↗
GORDON CARL L	Director	A Award deriv	2025-06-04	2025-06-06	10,500	—	$0	10,500	SEC↗
Knowles Julius	Director	A Award deriv	2025-06-04	2025-06-06	10,500	—	$0	10,500	SEC↗
BIENAIME JEAN JACQUES	Director	A Award	2025-06-04	2025-06-06	5,250	—	$0	5,450	SEC↗
Farzan Nima	Director	A Award	2025-06-04	2025-06-06	5,250	—	$0	5,250	SEC↗
GRAY MARY ANN	Director	A Award	2025-06-04	2025-06-06	5,250	—	$0	5,250	SEC↗
Seth Alpna	Director	A Award	2025-06-04	2025-06-06	5,250	—	$0	5,250	SEC↗
Nussbaum Ran	Director, 10% Owner	A Award	2025-06-04	2025-06-06	5,250	—	$0	5,250	SEC↗
Kariv Tomer	Director, 10% Owner	A Award	2025-06-04	2025-06-06	5,250	—	$0	5,250	SEC↗
GORDON CARL L	Director	A Award	2025-06-04	2025-06-06	5,250	—	$0	5,250	SEC↗
Knowles Julius	Director	A Award	2025-06-04	2025-06-06	5,250	—	$0	6,441	SEC↗
ADAR1 Capital Management, LLC	10% Owner	E Expire deriv	2025-05-16	2025-06-12	178	—	$0	0	SEC↗
ADAR1 Capital Management, LLC	10% Owner	E Expire deriv	2025-05-16	2025-06-12	300	—	$0	0	SEC↗
ADAR1 Capital Management, LLC	10% Owner	E Expire deriv	2025-05-16	2025-06-12	836	—	$0	0	SEC↗
ADAR1 Partners, LP	10% Owner	J Other deriv	2025-04-09	2025-04-11	325,000	—	$0	624,333	SEC↗
ADAR1 Partners, LP	10% Owner	J Other deriv	2025-04-09	2025-04-11	500,000	—	$0	124,333	SEC↗
ADAR1 Partners, LP	10% Owner	J Other deriv	2025-04-09	2025-04-11	74,333	—	$0	50,000	SEC↗
ADAR1 Partners, LP	10% Owner	P Buy	2025-04-09	2025-04-11	74,333	$10.33	$767.9K	4,392,737	SEC↗
ADAR1 Partners, LP	10% Owner	P Buy	2025-04-09	2025-04-11	18,560	$9.40	$174.5K	3,493,404	SEC↗
ADAR1 Partners, LP	10% Owner	P Buy	2025-04-09	2025-04-11	16,365	$9.40	$153.8K	743,558	SEC↗
ADAR1 Partners, LP	10% Owner	P Buy	2025-04-09	2025-04-11	325,000	$9.86	$3.20M	3,818,404	SEC↗
ADAR1 Partners, LP	10% Owner	P Buy	2025-04-09	2025-04-11	500,000	$10.33	$5.17M	4,318,404	SEC↗
Seehra Jasbir	CHIEF EXECUTIVE OFFICER	M Exercise deriv	2025-04-04	2025-04-07	49,367	—	$0	252,444	SEC↗
Seehra Jasbir	CHIEF EXECUTIVE OFFICER	M Exercise	2025-04-04	2025-04-07	49,367	$0.30	$14.8K	302,223	SEC↗
Rovaldi Christopher	Chief Operating Officer	A Award	2025-02-18	2025-02-19	60,000	—	$0	60,000	SEC↗
Regnante Keith	CHIEF FINANCIAL OFFICER	A Award	2025-02-18	2025-02-19	44,000	—	$0	44,000	SEC↗
CHYUNG YUNG H.	Chief Medical Officer	A Award	2025-02-18	2025-02-19	44,000	—	$0	44,000	SEC↗
CHYUNG YUNG H.	Chief Medical Officer	A Award deriv	2024-11-08	2024-11-12	110,000	—	$0	110,000	SEC↗
OrbiMed Genesis GP LLC	Director	S Sale	2024-08-13	2024-08-15	220,600	$44.01	$9.71M	899,212	SEC↗
OrbiMed Genesis GP LLC	Director	S Sale	2024-08-13	2024-08-15	29,400	$44.01	$1.29M	119,522	SEC↗
GORDON CARL L	Director	S Sale	2024-08-13	2024-08-15	29,400	$44.01	$1.29M	119,522	SEC↗
GORDON CARL L	Director	S Sale	2024-08-13	2024-08-15	220,600	$44.01	$9.71M	899,212	SEC↗
BIENAIME JEAN JACQUES	Director	A Award deriv	2024-06-03	2024-06-05	17,600	—	$0	17,600	SEC↗
Farzan Nima	Director	A Award deriv	2024-05-30	2024-06-03	10,000	—	$0	10,000	SEC↗
GORDON CARL L	Director	A Award deriv	2024-05-30	2024-06-03	10,000	—	$0	10,000	SEC↗
GRAY MARY ANN	Director	A Award deriv	2024-05-30	2024-06-03	10,000	—	$0	10,000	SEC↗
Knowles Julius	Director	A Award deriv	2024-05-30	2024-06-03	10,000	—	$0	10,000	SEC↗
Nussbaum Ran	Director, 10% Owner	A Award deriv	2024-05-30	2024-06-03	10,000	—	$0	10,000	SEC↗
Kariv Tomer	Director, 10% Owner	A Award deriv	2024-05-30	2024-06-03	10,000	—	$0	10,000	SEC↗
Seth Alpna	Director	A Award deriv	2024-05-30	2024-06-03	10,000	—	$0	10,000	SEC↗
Seehra Jasbir	CHIEF EXECUTIVE OFFICER	A Award deriv	2024-02-23	2024-02-23	125,000	—	$0	125,000	SEC↗
Cooper Simon Peter	CHIEF MEDICAL OFFICER	A Award deriv	2024-02-13	2024-02-15	40,000	—	$0	40,000	SEC↗
Rovaldi Christopher	CHIEF OPERATING OFFICER	A Award deriv	2024-02-13	2024-02-15	150,000	—	$0	150,000	SEC↗
Regnante Keith	CHIEF FINANCIAL OFFICER	A Award deriv	2024-02-13	2024-02-15	40,000	—	$0	40,000	SEC↗
Seehra Jasbir	CHIEF EXECUTIVE OFFICER	A Award deriv	2024-02-13	2024-02-15	125,000	—	$0	125,000	SEC↗
Regnante Keith	CHIEF FINANCIAL OFFICER	M Exercise	2024-01-04	2025-01-24	40,000	$16.00	$640.0K	40,000	SEC↗
Regnante Keith	CHIEF FINANCIAL OFFICER	S Sale	2024-01-04	2025-01-24	40,000	$45.29	$1.81M	0	SEC↗
Regnante Keith	Chief Financial Officer	M Exercise deriv	2024-01-04	2024-01-08	40,000	—	$0	53,622	SEC↗
Regnante Keith	Chief Financial Officer	S Sale	2023-11-04	2024-01-08	40,000	$45.29	$1.81M	0	SEC↗
Regnante Keith	Chief Financial Officer	M Exercise	2023-11-04	2024-01-08	40,000	$16.00	$640.0K	40,000	SEC↗
Regnante Keith	Chief Financial Officer	M Exercise deriv	2023-06-09	2023-06-12	20,000	—	$0	93,622	SEC↗
Regnante Keith	Chief Financial Officer	S Sale	2023-06-09	2023-06-12	15,993	$45.03	$720.2K	4,007	SEC↗
Regnante Keith	Chief Financial Officer	S Sale	2023-06-09	2023-06-12	1,428	$46.46	$66.3K	2,579	SEC↗
Regnante Keith	Chief Financial Officer	S Sale	2023-06-09	2023-06-12	2,579	$47.25	$121.9K	0	SEC↗
Regnante Keith	Chief Financial Officer	M Exercise	2023-06-09	2023-06-12	20,000	$16.00	$320.0K	20,000	SEC↗
Regnante Keith	Chief Financial Officer	M Exercise deriv	2023-06-08	2023-06-12	20,000	—	$0	113,622	SEC↗
Regnante Keith	Chief Financial Officer	M Exercise	2023-06-08	2023-06-12	20,000	$16.00	$320.0K	20,000	SEC↗
Regnante Keith	Chief Financial Officer	S Sale	2023-06-08	2023-06-12	17,301	$47.66	$824.6K	2,699	SEC↗
Regnante Keith	Chief Financial Officer	S Sale	2023-06-08	2023-06-12	2,699	$48.65	$131.3K	0	SEC↗
Farzan Nima	Director	A Award deriv	2023-06-06	2023-06-08	10,000	—	$0	10,000	SEC↗
GRAY MARY ANN	Director	A Award deriv	2023-06-06	2023-06-08	10,000	—	$0	10,000	SEC↗
Knowles Julius	Director	A Award deriv	2023-06-06	2023-06-08	10,000	—	$0	10,000	SEC↗
Nussbaum Ran	Director, 10% Owner	A Award deriv	2023-06-06	2023-06-08	10,000	—	$0	10,000	SEC↗
Kariv Tomer	Director, 10% Owner	A Award deriv	2023-06-06	2023-06-08	10,000	—	$0	10,000	SEC↗
Seth Alpna	Director	A Award deriv	2023-06-06	2023-06-08	10,000	—	$0	10,000	SEC↗
GORDON CARL L	Director	A Award deriv	2023-06-06	2023-06-08	10,000	—	$0	10,000	SEC↗
Seth Alpna	Director	A Award deriv	2023-05-01	2023-05-03	20,000	—	$0	20,000	SEC↗
Seehra Jasbir	Chief Executive Officer	M Exercise deriv	2023-04-08	2023-04-11	4,000	—	$0	45,087	SEC↗
Seehra Jasbir	Chief Executive Officer	M Exercise	2023-04-08	2023-04-11	4,000	$0.48	$1.9K	252,856	SEC↗
Seehra Jasbir	Chief Executive Officer	A Award deriv	2023-02-16	2023-02-17	200,000	—	$0	200,000	SEC↗
Regnante Keith	Chief Financial Officer	A Award deriv	2023-02-16	2023-02-17	40,000	—	$0	40,000	SEC↗
Cooper Simon Peter	Chief Medical Officer	A Award deriv	2023-02-16	2023-02-17	40,000	—	$0	40,000	SEC↗
Rovaldi Christopher	Chief Operating Officer	A Award deriv	2023-02-16	2023-02-17	100,000	—	$0	100,000	SEC↗
Kariv Tomer	Director, 10% Owner	X Exercise deriv	2022-11-29	2022-11-30	3,539	—	$0	0	SEC↗
Kariv Tomer	Director, 10% Owner	X Exercise deriv	2022-11-29	2022-11-30	1,723	—	$0	0	SEC↗
Kariv Tomer	Director, 10% Owner	X Exercise deriv	2022-11-29	2022-11-30	1,914	—	$0	0	SEC↗
Nussbaum Ran	Director, 10% Owner	X Exercise deriv	2022-11-29	2022-11-30	3,539	—	$0	0	SEC↗
Nussbaum Ran	Director, 10% Owner	X Exercise deriv	2022-11-29	2022-11-30	1,914	—	$0	0	SEC↗
Nussbaum Ran	Director, 10% Owner	X Exercise deriv	2022-11-29	2022-11-30	1,723	—	$0	0	SEC↗
Pontifax Late Stage GP Ltd.	10% Owner	X Exercise deriv	2022-11-29	2022-11-30	1,914	—	$0	0	SEC↗
Pontifax Late Stage GP Ltd.	10% Owner	X Exercise deriv	2022-11-29	2022-11-30	3,539	—	$0	0	SEC↗
Pontifax Late Stage GP Ltd.	10% Owner	X Exercise deriv	2022-11-29	2022-11-30	1,723	—	$0	0	SEC↗
Kariv Tomer	Director, 10% Owner	X Exercise	2022-11-29	2022-11-30	1,723	—	$0	1,121,045	SEC↗
Kariv Tomer	Director, 10% Owner	X Exercise	2022-11-29	2022-11-30	3,539	—	$0	2,284,612	SEC↗
Kariv Tomer	Director, 10% Owner	X Exercise	2022-11-29	2022-11-30	1,914	—	$0	1,226,412	SEC↗
Nussbaum Ran	Director, 10% Owner	X Exercise	2022-11-29	2022-11-30	1,723	—	$0	1,121,045	SEC↗
Nussbaum Ran	Director, 10% Owner	X Exercise	2022-11-29	2022-11-30	1,914	—	$0	1,226,412	SEC↗
Nussbaum Ran	Director, 10% Owner	X Exercise	2022-11-29	2022-11-30	3,539	—	$0	2,284,612	SEC↗
Pontifax Late Stage GP Ltd.	10% Owner	X Exercise	2022-11-29	2022-11-30	1,723	—	$0	1,121,045	SEC↗
Pontifax Late Stage GP Ltd.	10% Owner	X Exercise	2022-11-29	2022-11-30	3,539	—	$0	2,284,612	SEC↗
Pontifax Late Stage GP Ltd.	10% Owner	X Exercise	2022-11-29	2022-11-30	1,914	—	$0	1,226,412	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2022-07-15	2022-07-19	46,034	—	$0	8,755	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-07-15	2022-07-19	46,034	$30.00	$1.38M	95,100	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2022-07-15	2022-07-19	46,034	$0.30	$13.8K	141,134	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2022-07-13	2022-07-15	1,916	—	$0	54,789	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-07-13	2022-07-15	1,916	$30.00	$57.5K	95,100	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2022-07-13	2022-07-15	1,916	$0.30	$575	93,184	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2022-06-14	2022-06-14	9,400	—	$0	56,705	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2022-06-14	2022-06-14	9,400	$0.30	$2.8K	95,100	SEC↗
Seehra Jasbir	Chief Executive Officer	M Exercise deriv	2022-06-09	2022-06-10	5,000	—	$0	8,822	SEC↗
Seehra Jasbir	Chief Executive Officer	M Exercise	2022-06-09	2022-06-10	5,000	$0.30	$1.5K	248,856	SEC↗
Farzan Nima	Director	A Award deriv	2022-06-01	2022-06-03	8,293	—	$0	8,293	SEC↗
GORDON CARL L	Director	A Award deriv	2022-06-01	2022-06-03	8,293	—	$0	8,293	SEC↗
GRAY MARY ANN	Director	A Award deriv	2022-06-01	2022-06-03	8,293	—	$0	8,293	SEC↗
Kariv Tomer	Director, 10% Owner	A Award deriv	2022-06-01	2022-06-03	8,293	—	$0	8,293	SEC↗
Knowles Julius	Director	A Award deriv	2022-06-01	2022-06-03	8,293	—	$0	8,293	SEC↗
Nussbaum Ran	Director, 10% Owner	A Award deriv	2022-06-01	2022-06-03	8,293	—	$0	8,293	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2022-05-11	2022-05-13	5,300	—	$0	66,105	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-05-11	2022-05-13	16	$45.45	$727	85,700	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-05-11	2022-05-13	223	$44.23	$9.9K	85,716	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-05-11	2022-05-13	719	$43.32	$31.1K	85,939	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-05-11	2022-05-13	944	$42.49	$40.1K	86,658	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-05-11	2022-05-13	3,398	$41.26	$140.2K	87,602	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2022-05-11	2022-05-13	5,300	$0.30	$1.6K	91,000	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2022-04-11	2022-04-13	5,300	—	$0	71,405	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2022-04-11	2022-04-13	5,300	$0.30	$1.6K	91,000	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-04-11	2022-04-13	2,315	$63.50	$147.0K	86,259	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-04-11	2022-04-13	559	$64.15	$35.9K	85,700	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-04-11	2022-04-13	1,009	$62.32	$62.9K	88,574	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-04-11	2022-04-13	1,417	$61.37	$87.0K	89,583	SEC↗
Rovaldi Christopher	Chief Operating Officer	M Exercise deriv	2022-04-06	2022-04-08	1,728	—	$0	8,002	SEC↗
Rovaldi Christopher	Chief Operating Officer	M Exercise	2022-04-06	2022-04-08	1,728	$16.00	$27.6K	1,728	SEC↗
Rovaldi Christopher	Chief Operating Officer	S Sale	2022-04-06	2022-04-08	1,728	$65.00	$112.3K	0	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2022-04-04	2022-04-06	7,950	—	$0	76,705	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-04-04	2022-04-06	7,950	$60.00	$477.0K	85,700	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2022-04-04	2022-04-06	7,950	$0.30	$2.4K	93,650	SEC↗
Rovaldi Christopher	Chief Operating Officer	M Exercise deriv	2022-04-01	2022-04-05	864	—	$0	9,730	SEC↗
Rovaldi Christopher	Chief Operating Officer	S Sale	2022-04-01	2022-04-05	105	$58.83	$6.2K	0	SEC↗
Rovaldi Christopher	Chief Operating Officer	S Sale	2022-04-01	2022-04-05	366	$57.97	$21.2K	105	SEC↗
Rovaldi Christopher	Chief Operating Officer	M Exercise	2022-04-01	2022-04-05	864	$16.00	$13.8K	864	SEC↗
Rovaldi Christopher	Chief Operating Officer	S Sale	2022-04-01	2022-04-05	2	$54.34	$109	862	SEC↗
Rovaldi Christopher	Chief Operating Officer	S Sale	2022-04-01	2022-04-05	104	$56.20	$5.8K	758	SEC↗
Rovaldi Christopher	Chief Operating Officer	S Sale	2022-04-01	2022-04-05	287	$56.89	$16.3K	471	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2022-03-11	2022-03-15	2,650	—	$0	84,655	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-03-11	2022-03-15	875	$54.54	$47.7K	85,700	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2022-03-11	2022-03-15	2,650	$0.30	$795	88,350	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-03-11	2022-03-15	1,062	$52.43	$55.7K	87,288	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-03-11	2022-03-15	713	$53.36	$38.0K	86,575	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2022-02-11	2022-02-15	2,650	—	$0	87,305	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-02-11	2022-02-15	1,378	$52.35	$72.1K	85,899	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2022-02-11	2022-02-15	2,650	$0.30	$795	88,350	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-02-11	2022-02-15	1,073	$51.50	$55.3K	87,277	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-02-11	2022-02-15	199	$53.10	$10.6K	85,700	SEC↗
Rovaldi Christopher	Chief Operating Officer	A Award deriv	2022-02-01	2022-02-03	100,000	—	$0	100,000	SEC↗
Cooper Simon Peter	Chief Medical Officer	A Award deriv	2022-01-21	2022-01-25	50,000	—	$0	50,000	SEC↗
Lachey Jennifer	Chief Scientific Officer	A Award deriv	2022-01-21	2022-01-25	50,000	—	$0	50,000	SEC↗
Regnante Keith	Chief Financial Officer	A Award deriv	2022-01-21	2022-01-25	50,000	—	$0	50,000	SEC↗
Seehra Jasbir	Chief Executive Officer	A Award deriv	2022-01-21	2022-01-25	165,000	—	$0	165,000	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2022-01-11	2022-01-13	2,650	—	$0	89,955	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-01-11	2022-01-13	320	$52.01	$16.6K	88,030	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-01-11	2022-01-13	1,196	$53.56	$64.1K	86,834	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-01-11	2022-01-13	1,134	$54.45	$61.7K	85,700	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2022-01-11	2022-01-13	2,650	$0.30	$795	88,350	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2022-01-05	2022-01-07	2,650	—	$0	92,605	SEC↗
Knowles Julius	Director	S Sale	2022-01-05	2022-01-05	435	$59.00	$25.7K	232,727	SEC↗
Knowles Julius	Director	S Sale	2022-01-05	2022-01-05	667	$59.00	$39.4K	341,574	SEC↗
Knowles Julius	Director	S Sale	2022-01-05	2022-01-05	886	$58.20	$51.6K	233,162	SEC↗
Knowles Julius	Director	S Sale	2022-01-05	2022-01-05	1,356	$58.20	$78.9K	342,241	SEC↗
Knowles Julius	Director	S Sale	2022-01-05	2022-01-05	271	$57.23	$15.5K	234,048	SEC↗
Knowles Julius	Director	S Sale	2022-01-05	2022-01-05	419	$57.23	$24.0K	343,597	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2022-01-05	2022-01-07	2,650	$60.00	$159.0K	85,700	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2022-01-05	2022-01-07	2,650	$0.30	$795	88,350	SEC↗
Knowles Julius	Director	S Sale	2022-01-04	2022-01-05	794	$54.95	$43.6K	355,365	SEC↗
Knowles Julius	Director	S Sale	2022-01-04	2022-01-05	2,195	$58.86	$129.2K	234,319	SEC↗
Knowles Julius	Director	S Sale	2022-01-04	2022-01-05	3,367	$58.86	$198.2K	344,016	SEC↗
Knowles Julius	Director	S Sale	2022-01-04	2022-01-05	2,704	$57.99	$156.8K	236,514	SEC↗
Knowles Julius	Director	S Sale	2022-01-04	2022-01-05	4,151	$57.99	$240.7K	347,383	SEC↗
Knowles Julius	Director	S Sale	2022-01-04	2022-01-05	1,113	$56.95	$63.4K	239,218	SEC↗
Knowles Julius	Director	S Sale	2022-01-04	2022-01-05	1,707	$56.95	$97.2K	351,534	SEC↗
Knowles Julius	Director	S Sale	2022-01-04	2022-01-05	1,383	$56.10	$77.6K	240,331	SEC↗
Knowles Julius	Director	S Sale	2022-01-04	2022-01-05	2,124	$56.10	$119.2K	353,241	SEC↗
Knowles Julius	Director	S Sale	2022-01-04	2022-01-05	524	$54.95	$28.8K	241,714	SEC↗
Knowles Julius	Director	S Sale	2022-01-03	2022-01-05	2,406	$56.82	$136.7K	249,130	SEC↗
Knowles Julius	Director	S Sale	2022-01-03	2022-01-05	5,094	$57.83	$294.6K	361,644	SEC↗
Knowles Julius	Director	S Sale	2022-01-03	2022-01-05	3,318	$57.83	$191.9K	245,812	SEC↗
Knowles Julius	Director	S Sale	2022-01-03	2022-01-05	5,236	$58.96	$308.7K	356,408	SEC↗
Knowles Julius	Director	S Sale	2022-01-03	2022-01-05	3,412	$58.96	$201.2K	242,400	SEC↗
Knowles Julius	Director	S Sale	2022-01-03	2022-01-05	249	$59.40	$14.8K	356,159	SEC↗
Knowles Julius	Director	S Sale	2022-01-03	2022-01-05	162	$59.40	$9.6K	242,238	SEC↗
Knowles Julius	Director	S Sale	2022-01-03	2022-01-05	3,678	$56.82	$209.0K	366,738	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2021-12-15	2021-12-15	735	—	$0	95,255	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2021-12-15	2021-12-15	735	$50.00	$36.8K	85,700	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2021-12-15	2021-12-15	735	$0.30	$221	86,435	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2021-12-13	2021-12-15	1,915	—	$0	95,990	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2021-12-13	2021-12-15	1,915	$0.30	$575	87,615	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2021-12-13	2021-12-15	7	$53.64	$375	85,700	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2021-12-13	2021-12-15	1,518	$50.11	$76.1K	86,097	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2021-12-13	2021-12-15	390	$52.22	$20.4K	85,707	SEC↗
Knowles Julius	Director	S Sale	2021-12-02	2021-12-03	90	$54.67	$4.9K	251,536	SEC↗
Knowles Julius	Director	S Sale	2021-12-02	2021-12-03	138	$54.67	$7.5K	370,416	SEC↗
Knowles Julius	Director	S Sale	2021-12-02	2021-12-03	5,705	$53.86	$307.3K	251,626	SEC↗
Knowles Julius	Director	S Sale	2021-12-02	2021-12-03	8,747	$53.86	$471.1K	370,554	SEC↗
Knowles Julius	Director	S Sale	2021-12-02	2021-12-03	4,155	$53.17	$220.9K	257,331	SEC↗
Knowles Julius	Director	S Sale	2021-12-02	2021-12-03	6,372	$53.17	$338.8K	379,301	SEC↗
Knowles Julius	Director	S Sale	2021-12-02	2021-12-03	52	$52.00	$2.7K	261,486	SEC↗
Knowles Julius	Director	S Sale	2021-12-02	2021-12-03	79	$51.99	$4.1K	385,673	SEC↗
Knowles Julius	Director	S Sale	2021-12-01	2021-12-03	2,528	$55.71	$140.8K	387,318	SEC↗
Knowles Julius	Director	S Sale	2021-12-01	2021-12-03	3,372	$54.67	$184.3K	264,208	SEC↗
Knowles Julius	Director	S Sale	2021-12-01	2021-12-03	2,766	$53.48	$147.9K	267,580	SEC↗
Knowles Julius	Director	S Sale	2021-12-01	2021-12-03	5,168	$54.67	$282.5K	389,846	SEC↗
Knowles Julius	Director	S Sale	2021-12-01	2021-12-03	1,021	$56.27	$57.5K	261,538	SEC↗
Knowles Julius	Director	S Sale	2021-12-01	2021-12-03	1,566	$56.27	$88.1K	385,752	SEC↗
Knowles Julius	Director	S Sale	2021-12-01	2021-12-03	1,649	$55.71	$91.9K	262,559	SEC↗
Knowles Julius	Director	S Sale	2021-12-01	2021-12-03	4,243	$53.48	$226.9K	395,014	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2021-11-11	2021-11-12	5,300	—	$0	97,905	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2021-11-11	2021-11-12	739	$58.73	$43.4K	90,261	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2021-11-11	2021-11-12	4,561	$59.78	$272.7K	85,700	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2021-11-11	2021-11-12	5,300	$0.30	$1.6K	91,000	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2021-11-10	2021-11-12	15,900	—	$0	103,205	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2021-11-10	2021-11-12	15,900	$0.30	$4.8K	101,600	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2021-11-10	2021-11-12	15,900	$60.00	$954.0K	85,700	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise deriv	2021-11-04	2021-11-05	10,600	—	$0	119,105	SEC↗
Lachey Jennifer	Chief Scientific Officer	S Sale	2021-11-04	2021-11-05	10,600	$50.00	$530.0K	85,700	SEC↗
Lachey Jennifer	Chief Scientific Officer	M Exercise	2021-11-04	2021-11-05	10,600	$0.30	$3.2K	96,300	SEC↗
Knowles Julius	Director	S Sale	2021-11-03	2021-11-03	2,346	$42.45	$99.6K	270,346	SEC↗
Knowles Julius	Director	S Sale	2021-11-03	2021-11-03	3,597	$42.45	$152.7K	399,257	SEC↗
Knowles Julius	Director	S Sale	2021-11-03	2021-11-03	3,957	$41.65	$164.8K	272,692	SEC↗
Knowles Julius	Director	S Sale	2021-11-03	2021-11-03	6,067	$41.65	$252.7K	402,854	SEC↗
Knowles Julius	Director	S Sale	2021-11-02	2021-11-03	991	$43.04	$42.7K	276,649	SEC↗
Knowles Julius	Director	S Sale	2021-11-02	2021-11-03	1,518	$43.04	$65.3K	408,921	SEC↗
Knowles Julius	Director	S Sale	2021-11-02	2021-11-03	2,120	$42.10	$89.3K	277,640	SEC↗
Knowles Julius	Director	S Sale	2021-11-02	2021-11-03	3,252	$42.10	$136.9K	410,439	SEC↗
Knowles Julius	Director	S Sale	2021-11-01	2021-11-03	4,797	$42.43	$203.5K	279,760	SEC↗
Knowles Julius	Director	S Sale	2021-11-01	2021-11-03	7,350	$42.43	$311.9K	413,691	SEC↗
Knowles Julius	Director	S Sale	2021-11-01	2021-11-03	4,599	$41.85	$192.5K	284,557	SEC↗
Knowles Julius	Director	S Sale	2021-11-01	2021-11-03	7,057	$41.85	$295.3K	421,041	SEC↗
Knowles Julius	Director	S Sale	2021-10-20	2021-10-21	148	$37.55	$5.6K	290,619	SEC↗
Knowles Julius	Director	S Sale	2021-10-20	2021-10-21	1,463	$38.31	$56.0K	289,156	SEC↗
Knowles Julius	Director	S Sale	2021-10-20	2021-10-21	2,242	$38.31	$85.9K	428,098	SEC↗