MIST

Milestone Pharmaceuticals Inc.CIK 1408443 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for MIST PRO

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AI insights for MIST

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Duty Stuart	Director	4	$0	$0	2026-06-10
Wills Robert James	Director	11	$74.0K	$0	2026-06-10
Saik Andrew	Director	4	$0	$0	2026-06-10
Fischer Seth H. Z.	Director	5	$0	$0	2026-06-10
TOMSICEK MICHAEL JOHN	Director	8	$79.8K	$0	2026-06-10
Giles Lisa M.	Director	7	$0	$0	2026-06-10
PAPA JOSEPH C	Director	6	$0	$0	2026-06-10
Oliveto Joseph	President and CEO	24	$0	$555.7K	2026-04-16
Nelson Jeffrey Edward	Chief Operating Officer	12	$0	$158.2K	2026-02-02
Bharucha David	Chief Medical Officer	18	$47.4K	$158.2K	2026-02-02
Hasija Amit	CFO & EVP of Corp. Development	20	$0	$158.2K	2026-02-02
Muller Lorenz	Chief Commercial Officer	28	$0	$145.9K	2026-02-02
Liebert Debra K.	Director	11	$73.9K	$0	2025-07-11
Pasternak Richard C	Director	6	$52.0K	$0	2023-06-07
WONG RODERICK	10% Owner	5	$4.48M	$0	2023-03-22
RTW INVESTMENTS, LP	10% Owner	18	$66.98M	$13.56M	2022-09-07
TRUEX PAUL F	Director	12	$28.0K	$0	2022-05-31
Plat Francis	Chief Medical Officer	3	$0	$0	2021-03-24
FONDS DE SOLIDARITE DES TRAVAILLEURS DU QUEBEC	10% Owner	13	$6.50M	$4.32M	2020-07-29
Edick Paul R	Director	1	$0	$0	2020-06-05
Novo Holdings A/S	10% Owner	6	$5.00M	$3.84M	2019-11-25
Maness Timothy	Vice President, Finance	2	$0	$0	2019-09-09
Douville Philippe	Chief Scientific Officer	2	$0	$0	2019-05-13
BDC CAPITAL INC.	10% Owner	1	$3.00M	$0	2019-05-08

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Wills Robert James	Director	A Award deriv	2026-06-10	2026-06-12	77,000	—	$0	77,000	SEC↗
Duty Stuart	Director	A Award deriv	2026-06-10	2026-06-12	77,000	—	$0	77,000	SEC↗
Fischer Seth H. Z.	Director	A Award deriv	2026-06-10	2026-06-12	77,000	—	$0	77,000	SEC↗
Giles Lisa M.	Director	A Award deriv	2026-06-10	2026-06-12	77,000	—	$0	77,000	SEC↗
PAPA JOSEPH C	Director	A Award deriv	2026-06-10	2026-06-12	77,000	—	$0	77,000	SEC↗
Saik Andrew	Director	A Award deriv	2026-06-10	2026-06-12	77,000	—	$0	77,000	SEC↗
TOMSICEK MICHAEL JOHN	Director	A Award deriv	2026-06-10	2026-06-12	77,000	—	$0	77,000	SEC↗
Oliveto Joseph	President and CEO	S Sale	2026-04-16	2026-04-20	36,500	$2.26	$82.5K	446,244	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2026-02-02	2026-02-04	453,000	—	$0	453,000	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2026-02-02	2026-02-04	679,000	—	$0	679,000	SEC↗
Bharucha David	Chief Medical Officer	A Award deriv	2026-02-02	2026-02-04	204,000	—	$0	204,000	SEC↗
Bharucha David	Chief Medical Officer	A Award deriv	2026-02-02	2026-02-04	136,000	—	$0	136,000	SEC↗
Nelson Jeffrey Edward	Chief Operating Officer	A Award deriv	2026-02-02	2026-02-04	204,000	—	$0	204,000	SEC↗
Nelson Jeffrey Edward	Chief Operating Officer	A Award deriv	2026-02-02	2026-02-04	136,000	—	$0	136,000	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2026-02-02	2026-02-04	204,000	—	$0	204,000	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2026-02-02	2026-02-04	136,000	—	$0	136,000	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2026-02-02	2026-02-04	136,000	—	$0	136,000	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2026-02-02	2026-02-04	204,000	—	$0	204,000	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2026-02-02	2026-02-05	204,000	—	$0	204,000	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2026-02-02	2026-02-05	204,000	—	$0	204,000	SEC↗
Nelson Jeffrey Edward	Chief Operating Officer	A Award deriv	2026-02-02	2026-02-05	204,000	—	$0	204,000	SEC↗
Bharucha David	Chief Medical Officer	A Award deriv	2026-02-02	2026-02-05	204,000	—	$0	204,000	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2026-02-02	2026-02-05	679,000	—	$0	679,000	SEC↗
Oliveto Joseph	President and CEO	M Exercise deriv	2026-01-26	2026-01-28	66,600	—	$0	199,800	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	M Exercise deriv	2026-01-26	2026-01-28	20,100	—	$0	60,300	SEC↗
Muller Lorenz	Chief Commercial Officer	M Exercise deriv	2026-01-26	2026-01-28	20,100	—	$0	60,300	SEC↗
Nelson Jeffrey Edward	Chief Operating Officer	M Exercise deriv	2026-01-26	2026-01-28	20,100	—	$0	60,300	SEC↗
Bharucha David	Chief Medical Officer	M Exercise deriv	2026-01-26	2026-01-28	20,100	—	$0	60,300	SEC↗
Oliveto Joseph	President and CEO	M Exercise	2026-01-26	2026-01-28	66,600	—	$0	517,267	SEC↗
Oliveto Joseph	President and CEO	S Sale	2026-01-26	2026-01-28	34,523	$1.93	$66.6K	482,744	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	M Exercise	2026-01-26	2026-01-28	20,100	—	$0	112,093	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	S Sale	2026-01-26	2026-01-28	12,245	$1.93	$23.6K	99,848	SEC↗
Muller Lorenz	Chief Commercial Officer	S Sale	2026-01-26	2026-01-28	11,180	$1.93	$21.6K	205,406	SEC↗
Muller Lorenz	Chief Commercial Officer	M Exercise	2026-01-26	2026-01-28	20,100	—	$0	216,586	SEC↗
Nelson Jeffrey Edward	Chief Operating Officer	S Sale	2026-01-26	2026-01-28	12,245	$1.93	$23.6K	49,848	SEC↗
Nelson Jeffrey Edward	Chief Operating Officer	M Exercise	2026-01-26	2026-01-28	20,100	—	$0	62,093	SEC↗
Bharucha David	Chief Medical Officer	M Exercise	2026-01-26	2026-01-28	20,100	—	$0	125,426	SEC↗
Bharucha David	Chief Medical Officer	S Sale	2026-01-26	2026-01-28	12,245	$1.93	$23.6K	113,181	SEC↗
Oliveto Joseph	President and CEO	S Sale	2026-01-08	2026-01-09	43,000	$2.25	$96.8K	303,721	SEC↗
Oliveto Joseph	President and CEO	S Sale	2026-01-07	2026-01-09	500	$2.25	$1.1K	346,721	SEC↗
Oliveto Joseph	President and CEO	S Sale	2025-12-15	2026-01-28	133,054	$2.32	$308.7K	450,667	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	S Sale	2025-12-15	2026-01-28	58,007	$2.32	$134.6K	91,993	SEC↗
Muller Lorenz	Chief Commercial Officer	S Sale	2025-12-15	2026-01-28	53,566	$2.32	$124.3K	196,486	SEC↗
Nelson Jeffrey Edward	Chief Operating Officer	S Sale	2025-12-15	2026-01-28	58,007	$2.32	$134.6K	41,993	SEC↗
Bharucha David	Chief Medical Officer	S Sale	2025-12-15	2026-01-28	58,007	$2.32	$134.6K	105,326	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2025-12-12	2026-01-28	280,000	—	$0	280,000	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2025-12-12	2026-01-28	100,000	—	$0	100,000	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2025-12-12	2026-01-28	100,000	—	$0	100,000	SEC↗
Nelson Jeffrey Edward	Chief Operating Officer	A Award deriv	2025-12-12	2026-01-28	100,000	—	$0	100,000	SEC↗
Bharucha David	Chief Medical Officer	A Award deriv	2025-12-12	2026-01-28	100,000	—	$0	100,000	SEC↗
Oliveto Joseph	President and CEO	A Award	2025-12-12	2026-01-28	280,000	—	$0	583,721	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award	2025-12-12	2026-01-28	100,000	—	$0	150,000	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award	2025-12-12	2026-01-28	100,000	—	$0	250,052	SEC↗
Nelson Jeffrey Edward	Chief Operating Officer	A Award	2025-12-12	2026-01-28	100,000	—	$0	100,000	SEC↗
Bharucha David	Chief Medical Officer	A Award	2025-12-12	2026-01-28	100,000	—	$0	163,333	SEC↗
Muller Lorenz	Chief Commercial Officer	G Gift	2025-12-09	2025-12-11	25,000	—	$0	150,052	SEC↗
PAPA JOSEPH C	Director	A Award deriv	2025-07-11	2025-07-15	100,000	—	$0	100,000	SEC↗
PAPA JOSEPH C	Director	A Award deriv	2025-07-11	2025-07-15	100,000	—	$0	100,000	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2025-07-11	2025-07-15	66,666	—	$0	66,666	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2025-07-11	2025-07-15	66,666	—	$0	66,666	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2025-07-11	2025-07-15	66,666	—	$0	66,666	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2025-07-11	2025-07-15	66,666	—	$0	66,666	SEC↗
Bharucha David	Chief Medical Officer	A Award deriv	2025-07-11	2025-07-15	53,333	—	$0	53,333	SEC↗
Bharucha David	Chief Medical Officer	A Award deriv	2025-07-11	2025-07-15	53,333	—	$0	53,333	SEC↗
Wills Robert James	Director	A Award deriv	2025-07-11	2025-07-15	50,000	—	$0	50,000	SEC↗
Wills Robert James	Director	A Award deriv	2025-07-11	2025-07-15	50,000	—	$0	50,000	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2025-07-11	2025-07-15	50,000	—	$0	50,000	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2025-07-11	2025-07-15	50,000	—	$0	50,000	SEC↗
Liebert Debra K.	Director	A Award deriv	2025-07-11	2025-07-15	16,793	—	$0	16,793	SEC↗
Liebert Debra K.	Director	A Award deriv	2025-07-11	2025-07-15	16,793	—	$0	16,793	SEC↗
PAPA JOSEPH C	Director	A Award	2025-07-11	2025-07-15	100,000	—	$0	100,000	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award	2025-07-11	2025-07-15	66,666	—	$0	175,052	SEC↗
Oliveto Joseph	President and CEO	A Award	2025-07-11	2025-07-15	66,666	—	$0	347,221	SEC↗
Bharucha David	Chief Medical Officer	A Award	2025-07-11	2025-07-15	53,333	—	$0	63,333	SEC↗
Wills Robert James	Director	A Award	2025-07-11	2025-07-15	50,000	—	$0	65,000	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award	2025-07-11	2025-07-15	50,000	—	$0	50,000	SEC↗
Liebert Debra K.	Director	A Award	2025-07-11	2025-07-15	16,666	—	$0	16,793	SEC↗
Duty Stuart	Director	A Award deriv	2025-06-10	2025-06-12	40,000	—	$0	40,000	SEC↗
Fischer Seth H. Z.	Director	A Award deriv	2025-06-10	2025-06-12	40,000	—	$0	40,000	SEC↗
Giles Lisa M.	Director	A Award deriv	2025-06-10	2025-06-12	40,000	—	$0	40,000	SEC↗
PAPA JOSEPH C	Director	A Award deriv	2025-06-10	2025-06-12	40,000	—	$0	40,000	SEC↗
Saik Andrew	Director	A Award deriv	2025-06-10	2025-06-12	40,000	—	$0	40,000	SEC↗
TOMSICEK MICHAEL JOHN	Director	A Award deriv	2025-06-10	2025-06-12	40,000	—	$0	40,000	SEC↗
Wills Robert James	Director	A Award deriv	2025-06-10	2025-06-12	40,000	—	$0	40,000	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2025-01-27	2025-01-29	266,400	—	$0	266,400	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2025-01-27	2025-01-29	399,600	—	$0	399,600	SEC↗
Bharucha David	Chief Medical Officer	A Award deriv	2025-01-27	2025-01-29	120,600	—	$0	120,600	SEC↗
Bharucha David	Chief Medical Officer	A Award deriv	2025-01-27	2025-01-29	80,400	—	$0	80,400	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2025-01-27	2025-01-29	120,600	—	$0	120,600	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2025-01-27	2025-01-29	80,400	—	$0	80,400	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2025-01-27	2025-01-29	80,400	—	$0	80,400	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2025-01-27	2025-01-29	120,600	—	$0	120,600	SEC↗
Nelson Jeffrey Edward	Chief Operating Officer	A Award deriv	2025-01-27	2025-01-29	120,600	—	$0	120,600	SEC↗
Nelson Jeffrey Edward	Chief Operating Officer	A Award deriv	2025-01-27	2025-01-29	80,400	—	$0	80,400	SEC↗
PAPA JOSEPH C	Director	A Award deriv	2024-09-03	2024-09-05	80,000	—	$0	80,000	SEC↗
Wills Robert James	Director	A Award deriv	2024-08-28	2024-08-29	40,000	—	$0	40,000	SEC↗
Fischer Seth H. Z.	Director	A Award deriv	2024-08-28	2024-08-29	40,000	—	$0	40,000	SEC↗
Giles Lisa M.	Director	A Award deriv	2024-08-28	2024-08-29	40,000	—	$0	40,000	SEC↗
TOMSICEK MICHAEL JOHN	Director	A Award deriv	2024-08-28	2024-08-29	40,000	—	$0	40,000	SEC↗
Duty Stuart	Director	A Award deriv	2024-08-28	2024-08-29	40,000	—	$0	40,000	SEC↗
Saik Andrew	Director	A Award deriv	2024-08-28	2024-08-29	40,000	—	$0	40,000	SEC↗
Duty Stuart	Director	A Award deriv	2024-07-15	2024-07-17	80,000	—	$0	80,000	SEC↗
Saik Andrew	Director	A Award deriv	2024-07-15	2024-07-17	80,000	—	$0	80,000	SEC↗
Fischer Seth H. Z.	Director	A Award deriv	2023-06-07	2023-06-09	30,000	—	$0	30,000	SEC↗
Giles Lisa M.	Director	A Award deriv	2023-06-07	2023-06-09	30,000	—	$0	30,000	SEC↗
Liebert Debra K.	Director	A Award deriv	2023-06-07	2023-06-09	30,000	—	$0	30,000	SEC↗
Pasternak Richard C	Director	A Award deriv	2023-06-07	2023-06-09	30,000	—	$0	30,000	SEC↗
TOMSICEK MICHAEL JOHN	Director	A Award deriv	2023-06-07	2023-06-09	30,000	—	$0	30,000	SEC↗
Wills Robert James	Director	A Award deriv	2023-06-07	2023-06-09	30,000	—	$0	30,000	SEC↗
WONG RODERICK	10% Owner	J Other	2023-03-22	2023-03-24	1,059,000	—	$0	3,256,102	SEC↗
Fischer Seth H. Z.	Director	A Award deriv	2023-03-21	2023-03-23	42,000	—	$0	42,000	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2023-02-16	2023-02-17	360,000	—	$0	360,000	SEC↗
Bharucha David	Chief Medical Officer	A Award deriv	2023-02-16	2023-02-17	185,000	—	$0	185,000	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2023-02-16	2023-02-17	130,000	—	$0	130,000	SEC↗
Nelson Jeffrey Edward	Chief Operating Officer	A Award deriv	2023-02-16	2023-02-17	105,000	—	$0	105,000	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2023-02-16	2023-02-17	105,000	—	$0	105,000	SEC↗
Bharucha David	Chief Medical Officer	P Buy	2022-12-05	2022-12-05	7,000	$4.69	$32.8K	10,000	SEC↗
Bharucha David	Chief Medical Officer	P Buy	2022-12-01	2022-12-05	3,000	$4.86	$14.6K	3,000	SEC↗
Liebert Debra K.	Director	P Buy	2022-10-21	2022-10-21	4,000	$5.26	$21.0K	4,000	SEC↗
Liebert Debra K.	Director	P Buy	2022-10-20	2022-10-21	10,000	$5.29	$52.9K	10,000	SEC↗
Pasternak Richard C	Director	P Buy	2022-10-20	2022-10-21	10,000	$5.20	$52.0K	10,000	SEC↗
TOMSICEK MICHAEL JOHN	Director	P Buy	2022-10-19	2022-10-21	15,000	$5.32	$79.8K	15,000	SEC↗
Wills Robert James	Director	P Buy	2022-10-19	2022-10-21	15,000	$4.93	$74.0K	15,000	SEC↗
Liebert Debra K.	Director	J Other	2022-09-14	2022-09-15	127	—	$0	127	SEC↗
RTW INVESTMENTS, LP	10% Owner	S Sale	2022-09-07	2022-09-09	1,557,346	$8.71	$13.56M	4,315,102	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy	2022-09-07	2022-09-09	1,557,346	$8.71	$13.56M	4,315,102	SEC↗
Liebert Debra K.	Director	A Award deriv	2022-07-05	2022-08-11	30,000	—	$0	30,000	SEC↗
Giles Lisa M.	Director	A Award deriv	2022-07-05	2022-08-11	30,000	—	$0	30,000	SEC↗
Wills Robert James	Director	A Award deriv	2022-07-05	2022-08-11	30,000	—	$0	30,000	SEC↗
TOMSICEK MICHAEL JOHN	Director	A Award deriv	2022-07-05	2022-08-11	30,000	—	$0	30,000	SEC↗
Pasternak Richard C	Director	A Award deriv	2022-07-05	2022-08-11	30,000	—	$0	30,000	SEC↗
TRUEX PAUL F	Director	M Exercise deriv	2022-05-31	2022-06-01	822	—	$0	117	SEC↗
TRUEX PAUL F	Director	M Exercise deriv	2022-05-31	2022-06-01	45,072	—	$0	0	SEC↗
TRUEX PAUL F	Director	M Exercise deriv	2022-05-31	2022-06-01	8,016	—	$0	0	SEC↗
TRUEX PAUL F	Director	M Exercise deriv	2022-05-31	2022-06-01	22,870	—	$0	2,659	SEC↗
TRUEX PAUL F	Director	M Exercise	2022-05-31	2022-06-01	8,016	$1.12	$9.0K	8,016	SEC↗
TRUEX PAUL F	Director	M Exercise	2022-05-31	2022-06-01	45,072	$1.54	$69.4K	53,088	SEC↗
TRUEX PAUL F	Director	M Exercise	2022-05-31	2022-06-01	22,870	$1.54	$35.2K	75,958	SEC↗
TRUEX PAUL F	Director	M Exercise	2022-05-31	2022-06-01	822	$2.66	$2.2K	76,780	SEC↗
TRUEX PAUL F	Director	P Buy	2022-05-31	2022-06-01	5,000	$5.60	$28.0K	81,780	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2022-03-21	2022-03-23	160,000	—	$0	160,000	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2022-03-21	2022-03-23	175,000	—	$0	175,000	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2022-03-21	2022-03-23	500,000	—	$0	500,000	SEC↗
Bharucha David	Chief Medical Officer	A Award deriv	2022-02-15	2022-02-17	330,000	—	$0	330,000	SEC↗
Wills Robert James	Director	A Award deriv	2021-06-14	2021-07-29	30,000	—	$0	30,000	SEC↗
Giles Lisa M.	Director	A Award deriv	2021-06-14	2021-07-29	30,000	—	$0	30,000	SEC↗
Liebert Debra K.	Director	A Award deriv	2021-06-14	2021-07-29	30,000	—	$0	30,000	SEC↗
Pasternak Richard C	Director	A Award deriv	2021-06-14	2021-07-29	30,000	—	$0	30,000	SEC↗
TOMSICEK MICHAEL JOHN	Director	A Award deriv	2021-06-14	2021-07-29	30,000	—	$0	30,000	SEC↗
TRUEX PAUL F	Director	A Award deriv	2021-06-14	2021-07-29	30,000	—	$0	30,000	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy deriv	2021-05-21	2021-05-24	910,746	$5.48	$4.99M	8,518,257	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2021-03-24	2021-03-26	200,000	—	$0	200,000	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2021-03-24	2021-03-26	240,000	—	$0	240,000	SEC↗
Plat Francis	Chief Medical Officer	A Award deriv	2021-03-24	2021-03-26	130,000	—	$0	130,000	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2021-03-24	2021-03-26	670,000	—	$0	670,000	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy deriv	2020-10-27	2020-10-29	952,380	$5.24	$4.99M	7,607,511	SEC↗
Giles Lisa M.	Director	A Award deriv	2020-10-01	2020-10-05	30,000	—	$0	30,000	SEC↗
Wills Robert James	Director	A Award deriv	2020-10-01	2020-10-05	30,000	—	$0	30,000	SEC↗
Muller Lorenz	Chief Commercial Officer	M Exercise deriv	2020-08-26	2020-08-28	5,700	—	$0	49,754	SEC↗
Muller Lorenz	Chief Commercial Officer	M Exercise	2020-08-26	2020-08-28	5,700	$1.54	$8.8K	108,386	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	S Sale	2020-07-29	2020-07-30	500,000	$8.32	$4.16M	2,254,920	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	S Sale	2020-07-28	2020-07-30	19,863	$8.10	$160.9K	2,754,920	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy deriv	2020-07-22	2020-07-24	6,655,131	$3.75	$24.96M	6,655,131	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2020-06-05	2020-06-08	35,000	—	$0	35,000	SEC↗
Edick Paul R	Director	A Award deriv	2020-06-05	2020-06-08	15,000	—	$0	15,000	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2020-06-05	2020-06-08	115,000	—	$0	115,000	SEC↗
Liebert Debra K.	Director	A Award deriv	2020-06-05	2020-06-08	15,000	—	$0	15,000	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2020-06-05	2020-06-08	150,000	—	$0	150,000	SEC↗
Pasternak Richard C	Director	A Award deriv	2020-06-05	2020-06-08	15,000	—	$0	15,000	SEC↗
TOMSICEK MICHAEL JOHN	Director	A Award deriv	2020-06-05	2020-06-08	15,000	—	$0	15,000	SEC↗
TRUEX PAUL F	Director	A Award deriv	2020-06-05	2020-06-08	15,000	—	$0	15,000	SEC↗
Plat Francis	Chief Medical Officer	A Award deriv	2020-06-05	2020-06-08	35,000	—	$0	35,000	SEC↗
Muller Lorenz	Chief Commercial Officer	M Exercise deriv	2020-04-03	2020-06-08	18,043	—	$0	32,903	SEC↗
Muller Lorenz	Chief Commercial Officer	M Exercise deriv	2020-04-03	2020-06-08	32,528	—	$0	55,454	SEC↗
Muller Lorenz	Chief Commercial Officer	M Exercise	2020-04-03	2020-06-08	32,528	$1.54	$50.1K	84,643	SEC↗
Muller Lorenz	Chief Commercial Officer	M Exercise	2020-04-03	2020-06-08	18,043	$1.54	$27.8K	102,686	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy	2020-03-19	2020-03-19	5,870	$10.87	$63.8K	4,315,102	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy	2020-03-18	2020-03-19	2,705	$10.36	$28.0K	4,309,232	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy	2020-03-02	2020-03-19	78,263	$18.95	$1.48M	4,306,527	SEC↗
Muller Lorenz	Chief Commercial Officer	A Award deriv	2020-01-23	2020-01-24	60,000	—	$0	60,000	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2020-01-23	2020-01-24	82,000	—	$0	82,000	SEC↗
Oliveto Joseph	President and CEO	A Award deriv	2020-01-23	2020-01-24	200,000	—	$0	200,000	SEC↗
Plat Francis	Chief Medical Officer	A Award deriv	2020-01-23	2020-01-24	84,000	—	$0	84,000	SEC↗
WONG RODERICK	10% Owner	P Buy	2020-01-13	2020-01-13	270,000	$16.25	$4.39M	4,228,264	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy	2019-12-31	2020-01-02	21,438	$15.50	$332.3K	3,958,264	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy	2019-12-30	2020-01-02	1,333	$15.48	$20.6K	3,936,826	SEC↗
Oliveto Joseph	President and CEO	M Exercise deriv	2019-12-21	2020-06-08	7,400	—	$0	113,856	SEC↗
Oliveto Joseph	President and CEO	M Exercise	2019-12-21	2020-06-08	7,400	$1.54	$11.4K	280,555	SEC↗
Novo Holdings A/S	10% Owner	S Sale	2019-11-25	2019-11-27	240,000	$16.00	$3.84M	2,434,470	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy	2019-11-20	2019-11-22	400,000	$16.00	$6.40M	3,935,493	SEC↗
Pasternak Richard C	Director	A Award deriv	2019-11-12	2019-11-14	19,000	—	$0	19,000	SEC↗
Liebert Debra K.	Director	A Award deriv	2019-11-12	2019-11-14	19,000	—	$0	19,000	SEC↗
TRUEX PAUL F	Director	A Award deriv	2019-11-12	2019-11-14	4,000	—	$0	4,000	SEC↗
WONG RODERICK	10% Owner	P Buy	2019-10-15	2019-10-15	1,100	$18.00	$19.8K	3,535,493	SEC↗
WONG RODERICK	10% Owner	P Buy	2019-10-11	2019-10-15	4,208	$17.30	$72.8K	3,534,393	SEC↗
WONG RODERICK	10% Owner	P Buy	2019-10-10	2019-10-15	179	$16.00	$2.9K	3,530,185	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy	2019-10-03	2019-10-03	1,908	$18.31	$34.9K	3,530,006	SEC↗
Muller Lorenz	Chief Commercial Officer	M Exercise deriv	2019-10-01	2020-06-08	2,500	—	$0	87,982	SEC↗
Muller Lorenz	Chief Commercial Officer	M Exercise	2019-10-01	2020-06-08	2,500	$1.54	$3.9K	52,115	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy	2019-10-01	2019-10-03	6,242	$17.63	$110.0K	3,528,098	SEC↗
Hasija Amit	CFO & EVP of Corp. Developme	A Award deriv	2019-09-09	2019-09-11	147,000	—	$0	147,000	SEC↗
Maness Timothy	Chief Accounting Officer	A Award deriv	2019-09-09	2019-09-11	20,000	—	$0	20,000	SEC↗
Novo Holdings A/S	10% Owner	M Exercise deriv	2019-05-13	2019-05-14	964,089	—	$0	0	SEC↗
Novo Holdings A/S	10% Owner	M Exercise deriv	2019-05-13	2019-05-14	1,377,048	—	$0	0	SEC↗
Douville Philippe	Chief Scientific Officer	C Conversion deriv	2019-05-13	2019-05-14	4,124	—	$0	0	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	C Conversion deriv	2019-05-13	2019-05-15	574,292	—	$0	0	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	C Conversion deriv	2019-05-13	2019-05-15	139,849	—	$0	0	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	C Conversion deriv	2019-05-13	2019-05-15	798,974	—	$0	0	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	C Conversion deriv	2019-05-13	2019-05-15	437,203	—	$0	0	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	C Conversion deriv	2019-05-13	2019-05-15	306,092	—	$0	0	SEC↗
Novo Holdings A/S	10% Owner	P Buy	2019-05-13	2019-05-14	333,333	$15.00	$5.00M	2,674,470	SEC↗
Novo Holdings A/S	10% Owner	M Exercise	2019-05-13	2019-05-14	964,089	—	$0	2,341,137	SEC↗
Novo Holdings A/S	10% Owner	M Exercise	2019-05-13	2019-05-14	1,377,048	—	$0	1,377,048	SEC↗
Douville Philippe	Chief Scientific Officer	C Conversion	2019-05-13	2019-05-14	4,124	—	$0	43,392	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	C Conversion	2019-05-13	2019-05-15	574,292	—	$0	1,543,682	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	C Conversion	2019-05-13	2019-05-15	798,974	—	$0	969,390	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	C Conversion	2019-05-13	2019-05-15	139,849	—	$0	170,416	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	P Buy	2019-05-13	2019-05-15	433,333	$15.00	$6.50M	2,720,310	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	C Conversion	2019-05-13	2019-05-15	437,203	—	$0	1,980,885	SEC↗
FONDS DE SOLIDARITE DES TRAVAI	10% Owner	C Conversion	2019-05-13	2019-05-15	306,092	—	$0	2,286,977	SEC↗
RTW INVESTMENTS, LP	10% Owner	C Conversion deriv	2019-05-09	2019-05-09	203,942	—	$0	0	SEC↗
RTW INVESTMENTS, LP	10% Owner	C Conversion deriv	2019-05-09	2019-05-09	2,651,247	—	$0	0	SEC↗
RTW INVESTMENTS, LP	10% Owner	C Conversion	2019-05-09	2019-05-09	2,651,247	—	$0	2,651,247	SEC↗
RTW INVESTMENTS, LP	10% Owner	P Buy	2019-05-09	2019-05-09	666,667	$15.00	$10.00M	3,521,856	SEC↗
RTW INVESTMENTS, LP	10% Owner	C Conversion	2019-05-09	2019-05-09	203,942	—	$0	2,855,189	SEC↗
Maness Timothy	Vice President, Finance	A Award deriv	2019-05-08	2019-05-09	46,998	—	$0	46,998	SEC↗
BDC CAPITAL INC.	10% Owner	P Buy	2019-05-08	2019-05-09	200,000	$15.00	$3.00M	2,388,088	SEC↗