Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
$9.01M
11 trades · 5 insiders
Net · 90d
$-9.01M
Insiders on file
24
Daily buy vs sell · 90 days
■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| COATS LONNEL | Director | 2 | $0 | $0 | 2026-10-19 |
| Peterson Kristine | Director | 2 | $0 | $0 | 2026-10-19 |
| Congleton Jon | Chief Executive Officer, Director | 41 | $105.6K | $19.33M | 2026-09-30 |
| Slingsby Brian Taylor | Director, 10% Owner | 18 | $7.50M | $13.19M | 2026-09-22 |
| Warren Eric | Chief Commercial Officer | 18 | $0 | $3.70M | 2026-09-21 |
| Karydas Daphne | Director | 21 | $0 | $1.01M | 2026-09-15 |
| Ferguson James J. III | Chief Medical Officer | 4 | $0 | $0 | 2026-08-10 |
| Rodman David Malcom | Chief Medical Officer | 242 | $0 | $20.04M | 2026-08-10 |
| Shah Rajeev M. | Director | 2 | $8.76M | $0 | 2026-03-30 |
| Gold Alexander M | Director | 17 | $0 | $1.58M | 2026-02-19 |
| DiRocco Derek | Director | 5 | $0 | $0 | 2026-02-19 |
| Levy Adam Scott | CFO, Chief Bus. Off. and Secy. | 38 | $100.0K | $9.16M | 2026-02-19 |
| RA Capital Healthcare Fund LP | Director | 2 | $0 | $0 | 2026-02-19 |
| SBLENDORIO GLENN | Director | 5 | $0 | $0 | 2026-02-19 |
| AKKARAJU SRINIVAS | Director, 10% Owner | 10 | $38.10M | $0 | 2026-02-19 |
| Catalys Pacific Fund, LP | 10% Owner | 6 | $0 | $43.35M | 2025-11-20 |
| RA CAPITAL MANAGEMENT, L.P. | Director, 10% Owner | 5 | $30.00M | $0 | 2025-09-04 |
| RA Capital Nexus Fund III, L.P. | Director | 7 | $37.50M | $0 | 2025-03-13 |
| Samsara BioCapital, L.P. | 10% Owner | 4 | $15.60M | $0 | 2025-03-13 |
| Litzka Olivier | Director | 3 | $0 | $0 | 2024-05-22 |
| Kolchinsky Peter | Director | 1 | $0 | $0 | 2024-05-22 |
| Takahashi Takeshi | Director | 2 | $0 | $0 | 2023-07-12 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 5 | $5.00M | $0 | 2023-02-14 |
| Asam Alexander | Director | 1 | $0 | $0 | 2023-02-09 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Peterson Kristine | Director | A Award deriv | 2026-10-19 | 2026-10-20 | 16,600 | — | $0 | 16,600 | SEC↗ |
| Peterson Kristine | Director | A Award | 2026-10-19 | 2026-10-20 | 12,400 | — | $0 | 12,400 | SEC↗ |
| COATS LONNEL | Director | A Award deriv | 2026-10-19 | 2026-10-20 | 16,600 | — | $0 | 16,600 | SEC↗ |
| COATS LONNEL | Director | A Award | 2026-10-19 | 2026-10-20 | 12,400 | — | $0 | 12,400 | SEC↗ |
| Congleton Jon | Chief Executive Officer, Dir | S Sale | 2026-09-30 | 2026-10-02 | 75,000 | $25.46 | $1.91M | 528,621 | SEC↗ |
| Slingsby Brian Taylor | Director | S Sale | 2026-09-22 | 2026-09-24 | 104,320 | $28.81 | $3.01M | 7,805,718 | SEC↗ |
| Slingsby Brian Taylor | Director | S Sale | 2026-09-22 | 2026-09-24 | 104,320 | $28.81 | $3.01M | 7,805,718 | SEC↗ |
| Warren Eric | Chief Commercial Officer | M Exercise deriv | 2026-09-21 | 2026-09-22 | 7,438 | — | $0 | 230,563 | SEC↗ |
| Warren Eric | Chief Commercial Officer | M Exercise | 2026-09-21 | 2026-09-22 | 7,438 | $13.24 | $98.5K | 45,838 | SEC↗ |
| Warren Eric | Chief Commercial Officer | S Sale | 2026-09-21 | 2026-09-22 | 7,438 | $28.12 | $209.2K | 38,400 | SEC↗ |
| Warren Eric | Chief Commercial Officer | M Exercise deriv | 2026-09-21 | 2026-09-22 | 7,438 | — | $0 | 230,563 | SEC↗ |
| Warren Eric | Chief Commercial Officer | S Sale | 2026-09-21 | 2026-09-22 | 7,438 | $28.12 | $209.1K | 38,400 | SEC↗ |
| Warren Eric | Chief Commercial Officer | M Exercise | 2026-09-21 | 2026-09-22 | 7,438 | $13.24 | $98.5K | 45,838 | SEC↗ |
| Karydas Daphne | Director | M Exercise deriv | 2026-09-15 | 2026-09-17 | 3,000 | — | $0 | 35,000 | SEC↗ |
| Karydas Daphne | Director | S Sale | 2026-09-15 | 2026-09-17 | 3,000 | $28.58 | $85.7K | 6,200 | SEC↗ |
| Karydas Daphne | Director | M Exercise | 2026-09-15 | 2026-09-17 | 3,000 | $12.02 | $36.1K | 9,200 | SEC↗ |
| Karydas Daphne | Director | M Exercise deriv | 2026-09-15 | 2026-09-17 | 3,000 | — | $0 | 35,000 | SEC↗ |
| Karydas Daphne | Director | S Sale | 2026-09-15 | 2026-09-17 | 3,000 | $28.58 | $85.7K | 6,200 | SEC↗ |
| Karydas Daphne | Director | M Exercise | 2026-09-15 | 2026-09-17 | 3,000 | $12.02 | $36.1K | 9,200 | SEC↗ |
| Warren Eric | Chief Commercial Officer | M Exercise deriv | 2026-08-21 | 2026-08-25 | 7,437 | — | $0 | 238,001 | SEC↗ |
| Warren Eric | Chief Commercial Officer | S Sale | 2026-08-21 | 2026-08-25 | 7,437 | $25.98 | $193.2K | 38,400 | SEC↗ |
| Warren Eric | Chief Commercial Officer | M Exercise | 2026-08-21 | 2026-08-25 | 7,437 | $13.24 | $98.5K | 45,837 | SEC↗ |
| Warren Eric | Chief Commercial Officer | M Exercise deriv | 2026-08-21 | 2026-08-25 | 7,437 | — | $0 | 238,001 | SEC↗ |
| Warren Eric | Chief Commercial Officer | S Sale | 2026-08-21 | 2026-08-25 | 7,437 | $25.98 | $193.2K | 38,400 | SEC↗ |
| Warren Eric | Chief Commercial Officer | M Exercise | 2026-08-21 | 2026-08-25 | 7,437 | $13.24 | $98.5K | 45,837 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-08-10 | 2026-08-12 | 2,170 | — | $0 | 13,024 | SEC↗ |
| Ferguson James J. III | Chief Medical Officer | A Award deriv | 2026-08-10 | 2026-08-12 | 135,000 | — | $0 | 135,000 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-08-10 | 2026-08-12 | 2,170 | $27.09 | $58.8K | 51,384 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-08-10 | 2026-08-12 | 2,170 | $16.00 | $34.7K | 53,554 | SEC↗ |
| Ferguson James J. III | Chief Medical Officer | A Award | 2026-08-10 | 2026-08-12 | 102,400 | — | $0 | 102,400 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-08-10 | 2026-08-12 | 2,170 | — | $0 | 13,024 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-08-10 | 2026-08-12 | 2,170 | $27.09 | $58.8K | 51,384 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-08-10 | 2026-08-12 | 2,170 | $16.00 | $34.7K | 53,554 | SEC↗ |
| Ferguson James J. III | Chief Medical Officer | A Award deriv | 2026-08-10 | 2026-08-12 | 135,000 | — | $0 | 135,000 | SEC↗ |
| Ferguson James J. III | Chief Medical Officer | A Award | 2026-08-10 | 2026-08-12 | 102,400 | — | $0 | 102,400 | SEC↗ |
| Warren Eric | Chief Commercial Officer | M Exercise deriv | 2026-07-21 | 2026-07-23 | 7,438 | — | $0 | 245,438 | SEC↗ |
| Warren Eric | Chief Commercial Officer | M Exercise | 2026-07-21 | 2026-07-23 | 7,438 | $13.24 | $98.5K | 45,838 | SEC↗ |
| Warren Eric | Chief Commercial Officer | S Sale | 2026-07-21 | 2026-07-23 | 7,438 | $26.87 | $199.9K | 38,400 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-07-17 | 2026-07-20 | 416 | — | $0 | 3,334 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-07-17 | 2026-07-20 | 416 | $26.53 | $11.0K | 51,384 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-07-17 | 2026-07-20 | 416 | $15.44 | $6.4K | 51,800 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-07-15 | 2026-07-15 | 6,349 | $26.61 | $168.9K | 51,384 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-07-13 | 2026-07-15 | 4,167 | — | $0 | 79,167 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-07-13 | 2026-07-15 | 3,542 | — | $0 | 109,792 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-07-13 | 2026-07-15 | 6,349 | — | $0 | 0 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-07-13 | 2026-07-15 | 6,349 | $1.08 | $6.9K | 71,791 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-07-13 | 2026-07-15 | 3,542 | $10.20 | $36.1K | 61,275 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-07-13 | 2026-07-15 | 14,058 | $27.58 | $387.7K | 57,733 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-07-13 | 2026-07-15 | 4,167 | $14.25 | $59.4K | 65,442 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2026-07-13 | 2026-07-15 | 10,700 | $27.24 | $291.5K | 603,621 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-07-09 | 2026-07-10 | 2,171 | — | $0 | 15,194 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-07-09 | 2026-07-10 | 2,171 | $30.30 | $65.8K | 57,733 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-07-09 | 2026-07-10 | 2,171 | $16.00 | $34.7K | 59,904 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2026-06-30 | 2026-06-30 | 58,000 | $25.94 | $1.50M | 631,321 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2026-06-30 | 2026-06-30 | 17,000 | $26.82 | $455.9K | 614,321 | SEC↗ |
| Warren Eric | Chief Commercial Officer | M Exercise deriv | 2026-06-26 | 2026-06-30 | 104,124 | — | $0 | 252,876 | SEC↗ |
| Warren Eric | Chief Commercial Officer | S Sale | 2026-06-26 | 2026-06-30 | 104,124 | $25.90 | $2.70M | 38,400 | SEC↗ |
| Warren Eric | Chief Commercial Officer | M Exercise | 2026-06-26 | 2026-06-30 | 104,124 | $13.24 | $1.38M | 142,524 | SEC↗ |
| Karydas Daphne | Director | M Exercise deriv | 2026-06-17 | 2026-06-17 | 3,000 | — | $0 | 38,000 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-06-17 | 2026-06-17 | 417 | — | $0 | 3,750 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-06-17 | 2026-06-17 | 4,167 | — | $0 | 83,334 | SEC↗ |
| Karydas Daphne | Director | S Sale | 2026-06-17 | 2026-06-17 | 3,000 | $25.00 | $75.0K | 6,200 | SEC↗ |
| Karydas Daphne | Director | M Exercise | 2026-06-17 | 2026-06-17 | 3,000 | $12.02 | $36.1K | 9,200 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-06-17 | 2026-06-17 | 4,167 | $14.25 | $59.4K | 61,262 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-06-17 | 2026-06-17 | 4,584 | $25.00 | $114.6K | 57,095 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-06-17 | 2026-06-17 | 417 | $15.44 | $6.4K | 61,679 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-06-15 | 2026-06-17 | 3,542 | — | $0 | 113,334 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-06-15 | 2026-06-17 | 9,890 | $23.81 | $235.5K | 57,095 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-06-15 | 2026-06-17 | 3,542 | $10.20 | $36.1K | 66,985 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-06-12 | 2026-06-12 | 6,349 | — | $0 | 6,349 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-06-12 | 2026-06-12 | 6,349 | $1.08 | $6.9K | 69,792 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-06-12 | 2026-06-12 | 6,349 | $23.93 | $151.9K | 63,443 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-06-10 | 2026-06-12 | 2,170 | — | $0 | 17,365 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-06-10 | 2026-06-12 | 2,170 | $16.00 | $34.7K | 65,613 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-06-10 | 2026-06-12 | 2,170 | $25.00 | $54.3K | 63,443 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-05-18 | 2026-05-19 | 417 | — | $0 | 4,167 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-05-18 | 2026-05-19 | 417 | $27.55 | $11.5K | 63,443 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-05-18 | 2026-05-19 | 417 | $15.44 | $6.4K | 63,860 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-05-13 | 2026-05-13 | 3,541 | — | $0 | 116,876 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-05-13 | 2026-05-13 | 4,166 | — | $0 | 87,501 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-05-13 | 2026-05-13 | 14,056 | $28.58 | $401.7K | 63,443 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-05-13 | 2026-05-13 | 3,541 | $10.20 | $36.1K | 73,333 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-05-13 | 2026-05-13 | 4,166 | $14.25 | $59.4K | 77,499 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-05-12 | 2026-05-13 | 6,348 | — | $0 | 12,698 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-05-12 | 2026-05-13 | 6,348 | $29.36 | $186.4K | 69,792 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-05-12 | 2026-05-13 | 6,348 | $1.08 | $6.9K | 76,140 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-05-11 | 2026-05-13 | 2,171 | — | $0 | 19,535 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-05-11 | 2026-05-13 | 2,171 | $16.00 | $34.7K | 71,963 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-05-11 | 2026-05-13 | 2,171 | $29.71 | $64.5K | 69,792 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-04-17 | 2026-04-21 | 416 | — | $0 | 4,584 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-04-17 | 2026-04-21 | 416 | $15.44 | $6.4K | 70,208 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-04-17 | 2026-04-21 | 416 | $31.33 | $13.0K | 69,792 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-04-15 | 2026-04-15 | 6,348 | $27.66 | $175.6K | 69,792 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-04-13 | 2026-04-15 | 4,167 | — | $0 | 91,667 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-04-13 | 2026-04-15 | 6,349 | — | $0 | 19,046 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-04-13 | 2026-04-15 | 3,542 | — | $0 | 120,417 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2026-04-13 | 2026-04-15 | 15,730 | $26.83 | $422.0K | 689,321 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-04-13 | 2026-04-15 | 4,167 | $14.25 | $59.4K | 90,198 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-04-13 | 2026-04-15 | 14,058 | $26.54 | $373.1K | 76,140 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-04-13 | 2026-04-15 | 6,349 | $1.08 | $6.9K | 82,489 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-04-13 | 2026-04-15 | 3,542 | $10.20 | $36.1K | 86,031 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-04-09 | 2026-04-13 | 2,170 | — | $0 | 21,706 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-04-09 | 2026-04-13 | 2,170 | $27.38 | $59.4K | 76,140 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-04-09 | 2026-04-13 | 2,170 | $16.00 | $34.7K | 78,310 | SEC↗ |
| Karydas Daphne | Director | M Exercise deriv | 2026-03-31 | 2026-04-02 | 3,000 | — | $0 | 41,000 | SEC↗ |
| Karydas Daphne | Director | S Sale | 2026-03-31 | 2026-04-02 | 3,000 | $25.00 | $75.0K | 6,200 | SEC↗ |
| Karydas Daphne | Director | M Exercise | 2026-03-31 | 2026-04-02 | 3,000 | $12.02 | $36.1K | 9,200 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2026-03-31 | 2026-04-02 | 55,183 | $26.54 | $1.46M | 705,504 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2026-03-31 | 2026-04-02 | 453 | $27.05 | $12.3K | 705,051 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2026-03-31 | 2026-04-02 | 19,364 | $25.50 | $493.8K | 760,687 | SEC↗ |
| Shah Rajeev M. | Director | P Buy | 2026-03-30 | 2026-03-31 | 58,300 | $24.16 | $1.41M | 5,825,521 | SEC↗ |
| Shah Rajeev M. | Director | P Buy | 2026-03-27 | 2026-03-31 | 310,700 | $23.67 | $7.35M | 5,767,221 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-03-17 | 2026-03-17 | 417 | — | $0 | 5,000 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-03-17 | 2026-03-17 | 417 | $15.44 | $6.4K | 76,557 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-03-17 | 2026-03-17 | 417 | $25.65 | $10.7K | 76,140 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-03-13 | 2026-03-16 | 4,167 | — | $0 | 95,834 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-03-13 | 2026-03-16 | 3,542 | — | $0 | 123,959 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-03-13 | 2026-03-16 | 3,542 | $10.20 | $36.1K | 86,031 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-03-13 | 2026-03-16 | 3,079 | $27.37 | $84.3K | 76,393 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-03-13 | 2026-03-16 | 10,726 | $25.91 | $277.9K | 79,472 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-03-13 | 2026-03-16 | 4,167 | $14.25 | $59.4K | 90,198 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-03-13 | 2026-03-16 | 253 | $27.82 | $7.0K | 76,140 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-03-12 | 2026-03-16 | 6,348 | — | $0 | 25,395 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-03-12 | 2026-03-16 | 6,348 | $1.08 | $6.9K | 88,837 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-03-12 | 2026-03-16 | 6,348 | $27.37 | $173.7K | 82,489 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-03-09 | 2026-03-10 | 2,171 | — | $0 | 23,876 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-03-09 | 2026-03-10 | 2,171 | $26.84 | $58.3K | 82,489 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-03-09 | 2026-03-10 | 2,171 | $16.00 | $34.7K | 84,660 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | A Award deriv | 2026-02-19 | 2026-02-20 | 53,300 | — | $0 | 53,300 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | A Award deriv | 2026-02-19 | 2026-02-20 | 51,300 | — | $0 | 51,300 | SEC↗ |
| DiRocco Derek | Director | A Award deriv | 2026-02-19 | 2026-02-20 | 8,300 | — | $0 | 8,300 | SEC↗ |
| AKKARAJU SRINIVAS | Director, 10% Owner | A Award deriv | 2026-02-19 | 2026-02-20 | 8,300 | — | $0 | 8,300 | SEC↗ |
| Slingsby Brian Taylor | Director, 10% Owner | J Other deriv | 2026-02-19 | 2026-02-20 | 8,300 | — | $0 | 8,300 | SEC↗ |
| Slingsby Brian Taylor | Director, 10% Owner | J Other deriv | 2026-02-19 | 2026-02-20 | 8,300 | — | $0 | 0 | SEC↗ |
| Slingsby Brian Taylor | Director, 10% Owner | A Award deriv | 2026-02-19 | 2026-02-20 | 8,300 | — | $0 | 8,300 | SEC↗ |
| Karydas Daphne | Director | A Award deriv | 2026-02-19 | 2026-02-20 | 8,300 | — | $0 | 8,300 | SEC↗ |
| Gold Alexander M | Director | A Award deriv | 2026-02-19 | 2026-02-20 | 8,300 | — | $0 | 8,300 | SEC↗ |
| SBLENDORIO GLENN | Director | A Award deriv | 2026-02-19 | 2026-02-20 | 8,300 | — | $0 | 8,300 | SEC↗ |
| Congleton Jon | Chief Executive Officer | A Award deriv | 2026-02-19 | 2026-02-20 | 187,900 | — | $0 | 187,900 | SEC↗ |
| RA Capital Healthcare Fund LP | Director | A Award deriv | 2026-02-19 | 2026-02-20 | 8,300 | — | $0 | 8,300 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | A Award | 2026-02-19 | 2026-02-20 | 39,900 | — | $0 | 48,538 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | A Award | 2026-02-19 | 2026-02-20 | 38,400 | — | $0 | 82,489 | SEC↗ |
| DiRocco Derek | Director | A Award | 2026-02-19 | 2026-02-20 | 6,200 | — | $0 | 6,200 | SEC↗ |
| AKKARAJU SRINIVAS | Director, 10% Owner | A Award | 2026-02-19 | 2026-02-20 | 6,200 | — | $0 | 6,200 | SEC↗ |
| Slingsby Brian Taylor | Director, 10% Owner | A Award | 2026-02-19 | 2026-02-20 | 6,200 | — | $0 | 6,200 | SEC↗ |
| Slingsby Brian Taylor | Director, 10% Owner | J Other | 2026-02-19 | 2026-02-20 | 6,200 | — | $0 | 7,910,038 | SEC↗ |
| Slingsby Brian Taylor | Director, 10% Owner | J Other | 2026-02-19 | 2026-02-20 | 6,200 | — | $0 | 0 | SEC↗ |
| Karydas Daphne | Director | A Award | 2026-02-19 | 2026-02-20 | 6,200 | — | $0 | 6,200 | SEC↗ |
| Gold Alexander M | Director | A Award | 2026-02-19 | 2026-02-20 | 6,200 | — | $0 | 6,200 | SEC↗ |
| SBLENDORIO GLENN | Director | A Award | 2026-02-19 | 2026-02-20 | 6,200 | — | $0 | 6,200 | SEC↗ |
| Congleton Jon | Chief Executive Officer | A Award | 2026-02-19 | 2026-02-20 | 140,900 | — | $0 | 780,051 | SEC↗ |
| RA Capital Healthcare Fund LP | Director | A Award | 2026-02-19 | 2026-02-20 | 6,200 | — | $0 | 6,200 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-02-17 | 2026-02-17 | 417 | — | $0 | 5,417 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-02-17 | 2026-02-17 | 417 | $15.44 | $6.4K | 44,506 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-02-17 | 2026-02-17 | 417 | $27.59 | $11.5K | 44,089 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-02-13 | 2026-02-13 | 4,166 | — | $0 | 100,001 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-02-13 | 2026-02-13 | 3,541 | — | $0 | 127,501 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-02-13 | 2026-02-13 | 3,541 | $10.20 | $36.1K | 53,978 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-02-13 | 2026-02-13 | 3,541 | $27.33 | $96.8K | 50,437 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-02-13 | 2026-02-13 | 4,166 | $14.25 | $59.4K | 54,603 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-02-13 | 2026-02-13 | 6,348 | $27.58 | $175.1K | 44,089 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-02-13 | 2026-02-13 | 4,166 | $27.33 | $113.9K | 50,437 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-02-12 | 2026-02-13 | 6,349 | — | $0 | 31,743 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-02-12 | 2026-02-13 | 6,349 | $1.08 | $6.9K | 56,786 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-02-12 | 2026-02-13 | 5,828 | $28.94 | $168.7K | 50,958 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-02-12 | 2026-02-13 | 521 | $29.64 | $15.4K | 50,437 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-02-09 | 2026-02-11 | 2,171 | — | $0 | 26,047 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-02-09 | 2026-02-11 | 2,171 | $16.00 | $34.7K | 52,608 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-02-09 | 2026-02-11 | 2,171 | $30.21 | $65.6K | 50,437 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-20 | 2026-01-20 | 416 | — | $0 | 5,834 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-20 | 2026-01-20 | 416 | $15.44 | $6.4K | 50,853 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-01-20 | 2026-01-20 | 416 | $32.10 | $13.4K | 50,437 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-01-14 | 2026-01-15 | 11,367 | $32.61 | $370.7K | 50,437 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-13 | 2026-01-15 | 3,542 | — | $0 | 131,042 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-13 | 2026-01-15 | 4,167 | — | $0 | 104,167 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-13 | 2026-01-15 | 3,542 | $10.20 | $36.1K | 65,346 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-13 | 2026-01-15 | 4,167 | $14.25 | $59.4K | 69,513 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-01-13 | 2026-01-15 | 7,709 | $32.75 | $252.5K | 61,804 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-12 | 2026-01-13 | 6,348 | — | $0 | 38,092 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-01-12 | 2026-01-13 | 6,348 | $32.32 | $205.2K | 61,804 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-12 | 2026-01-13 | 6,348 | $1.08 | $6.9K | 68,152 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2026-01-12 | 2026-01-13 | 10,758 | $32.14 | $345.8K | 8,638 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2026-01-12 | 2026-01-13 | 7,117 | $33.15 | $235.9K | 639,151 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2026-01-12 | 2026-01-13 | 9,119 | $32.21 | $293.7K | 646,268 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-09 | 2026-01-13 | 2,170 | — | $0 | 28,218 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-01-09 | 2026-01-13 | 2,170 | $33.27 | $72.2K | 61,804 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-09 | 2026-01-13 | 2,170 | $16.00 | $34.7K | 63,974 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-05 | 2026-01-06 | 53,630 | — | $0 | 30,388 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-05 | 2026-01-06 | 26,069 | — | $0 | 134,584 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-05 | 2026-01-06 | 10,121 | — | $0 | 6,250 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-05 | 2026-01-06 | 28,038 | — | $0 | 44,440 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-05 | 2026-01-06 | 67,473 | — | $0 | 108,334 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-05 | 2026-01-06 | 28,038 | $1.08 | $30.3K | 97,226 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-01-05 | 2026-01-06 | 139,245 | $34.83 | $4.85M | 115,274 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-05 | 2026-01-06 | 67,473 | $14.25 | $961.5K | 254,519 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-05 | 2026-01-06 | 53,630 | $16.00 | $858.1K | 187,046 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-05 | 2026-01-06 | 26,069 | $10.20 | $265.9K | 133,416 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-05 | 2026-01-06 | 10,121 | $15.44 | $156.3K | 107,347 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-01-05 | 2026-01-06 | 53,470 | $35.53 | $1.90M | 61,804 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-02 | 2026-01-06 | 24,193 | — | $0 | 175,807 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-02 | 2026-01-06 | 20,168 | — | $0 | 84,018 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-02 | 2026-01-06 | 9,347 | — | $0 | 160,653 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-02 | 2026-01-06 | 3,629 | — | $0 | 16,371 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2026-01-02 | 2026-01-06 | 10,053 | — | $0 | 72,478 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2026-01-02 | 2026-01-06 | 70,037 | $35.87 | $2.51M | 69,188 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-02 | 2026-01-06 | 24,193 | $14.25 | $344.8K | 139,225 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-02 | 2026-01-06 | 20,168 | $16.00 | $322.7K | 115,032 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-02 | 2026-01-06 | 9,347 | $10.20 | $95.3K | 94,864 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-02 | 2026-01-06 | 3,629 | $15.44 | $56.0K | 85,517 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2026-01-02 | 2026-01-06 | 10,053 | $1.08 | $10.9K | 81,888 | SEC↗ |
| Congleton Jon | Chief Executive Officer | M Exercise deriv | 2025-11-21 | 2025-11-24 | 24,082 | — | $0 | 0 | SEC↗ |
| Congleton Jon | Chief Executive Officer | M Exercise | 2025-11-21 | 2025-11-24 | 24,082 | $0.54 | $13.0K | 655,387 | SEC↗ |
| Catalys Pacific Fund, LP | 10% Owner | S Sale | 2025-11-20 | 2025-11-21 | 1,000,000 | $43.35 | $43.35M | 7,903,838 | SEC↗ |
| Gold Alexander M | Director | M Exercise deriv | 2025-11-13 | 2025-11-13 | 10,000 | — | $0 | 34,000 | SEC↗ |
| Gold Alexander M | Director | M Exercise deriv | 2025-11-13 | 2025-11-13 | 2,742 | — | $0 | 8,225 | SEC↗ |
| Karydas Daphne | Director | M Exercise deriv | 2025-11-13 | 2025-11-13 | 15,000 | — | $0 | 17,900 | SEC↗ |
| Gold Alexander M | Director | S Sale | 2025-11-13 | 2025-11-13 | 12,742 | $46.50 | $592.5K | 0 | SEC↗ |
| Gold Alexander M | Director | M Exercise | 2025-11-13 | 2025-11-13 | 10,000 | $12.69 | $126.9K | 12,742 | SEC↗ |
| Gold Alexander M | Director | M Exercise | 2025-11-13 | 2025-11-13 | 2,742 | $10.20 | $28.0K | 2,742 | SEC↗ |
| Karydas Daphne | Director | M Exercise | 2025-11-13 | 2025-11-13 | 15,000 | $10.20 | $153.0K | 15,000 | SEC↗ |
| Karydas Daphne | Director | S Sale | 2025-11-13 | 2025-11-13 | 10,115 | $45.81 | $463.4K | 4,885 | SEC↗ |
| Karydas Daphne | Director | S Sale | 2025-11-13 | 2025-11-13 | 4,885 | $46.36 | $226.5K | 0 | SEC↗ |
| Gold Alexander M | Director | M Exercise deriv | 2025-11-12 | 2025-11-13 | 6,933 | — | $0 | 10,967 | SEC↗ |
| Gold Alexander M | Director | S Sale | 2025-11-12 | 2025-11-13 | 1,933 | $47.28 | $91.4K | 0 | SEC↗ |
| Gold Alexander M | Director | S Sale | 2025-11-12 | 2025-11-13 | 5,000 | $46.50 | $232.5K | 1,933 | SEC↗ |
| Gold Alexander M | Director | M Exercise | 2025-11-12 | 2025-11-13 | 6,933 | $10.20 | $70.7K | 6,933 | SEC↗ |
| Gold Alexander M | Director | M Exercise deriv | 2025-11-11 | 2025-11-13 | 15,000 | — | $0 | 17,900 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | M Exercise deriv | 2025-11-11 | 2025-11-13 | 20,547 | — | $0 | 135,674 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | M Exercise deriv | 2025-11-11 | 2025-11-13 | 34,414 | — | $0 | 20,662 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | M Exercise deriv | 2025-11-11 | 2025-11-13 | 44,079 | — | $0 | 91,592 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | M Exercise deriv | 2025-11-11 | 2025-11-13 | 6,613 | — | $0 | 4,888 | SEC↗ |
| Gold Alexander M | Director | S Sale | 2025-11-11 | 2025-11-13 | 10,000 | $42.43 | $424.3K | 5,000 | SEC↗ |
| Gold Alexander M | Director | M Exercise | 2025-11-11 | 2025-11-13 | 15,000 | $10.20 | $153.0K | 15,000 | SEC↗ |
| Gold Alexander M | Director | S Sale | 2025-11-11 | 2025-11-13 | 5,000 | $47.08 | $235.4K | 0 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2025-11-11 | 2025-11-13 | 12,806 | $41.64 | $533.2K | 818,499 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2025-11-11 | 2025-11-13 | 8,862 | $42.31 | $375.0K | 809,637 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2025-11-11 | 2025-11-13 | 4,000 | $43.50 | $174.0K | 805,637 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2025-11-11 | 2025-11-13 | 29,207 | $45.20 | $1.32M | 776,430 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2025-11-11 | 2025-11-13 | 112,275 | $45.83 | $5.15M | 664,155 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2025-11-11 | 2025-11-13 | 32,850 | $46.89 | $1.54M | 631,305 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | M Exercise | 2025-11-11 | 2025-11-13 | 6,613 | $15.44 | $102.1K | 138,920 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | M Exercise | 2025-11-11 | 2025-11-13 | 44,079 | $14.25 | $628.1K | 132,307 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-11-11 | 2025-11-13 | 32,718 | $46.88 | $1.53M | 19,396 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | M Exercise | 2025-11-11 | 2025-11-13 | 20,547 | $10.20 | $209.6K | 53,814 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-11-11 | 2025-11-13 | 1,015 | $42.00 | $42.6K | 137,905 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-11-11 | 2025-11-13 | 11,295 | $41.87 | $472.9K | 126,610 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-11-11 | 2025-11-13 | 1,561 | $42.68 | $66.6K | 125,049 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-11-11 | 2025-11-13 | 12,952 | $41.65 | $539.5K | 112,097 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-11-11 | 2025-11-13 | 8,485 | $42.34 | $359.3K | 103,612 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-11-11 | 2025-11-13 | 4,142 | $43.50 | $180.2K | 99,470 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-11-11 | 2025-11-13 | 8,456 | $45.18 | $382.0K | 91,014 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-11-11 | 2025-11-13 | 38,900 | $45.93 | $1.79M | 52,114 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | M Exercise | 2025-11-11 | 2025-11-13 | 34,414 | $16.00 | $550.6K | 88,228 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2025-10-15 | 2025-10-15 | 10,369 | $43.01 | $446.0K | 71,155 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2025-10-13 | 2025-10-15 | 13,548 | $42.63 | $577.6K | 832,857 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2025-10-13 | 2025-10-15 | 1,552 | $43.03 | $66.8K | 831,305 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-10-13 | 2025-10-15 | 3,392 | $42.26 | $143.3K | 116,865 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-10-13 | 2025-10-15 | 7,366 | $41.90 | $308.6K | 120,257 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2025-09-15 | 2025-09-16 | 2,065 | $36.47 | $75.3K | 81,524 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2025-09-15 | 2025-09-16 | 9,302 | $35.90 | $333.9K | 83,589 | SEC↗ |
| RA CAPITAL MANAGEMENT, L.P. | Director | P Buy | 2025-09-04 | 2025-09-08 | 1,176,470 | $25.50 | $30.00M | 5,456,521 | SEC↗ |
| AKKARAJU SRINIVAS | Director | P Buy | 2025-09-04 | 2025-09-08 | 588,235 | $25.50 | $15.00M | 588,235 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2025-08-13 | 2025-08-14 | 11,365 | $12.93 | $146.9K | 92,891 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2025-08-12 | 2025-08-14 | 6,349 | — | $0 | 82,531 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2025-08-12 | 2025-08-14 | 6,349 | $1.08 | $6.9K | 104,256 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-07-30 | 2025-07-30 | 8,425 | $15.10 | $127.2K | 132,934 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-07-30 | 2025-07-30 | 51,500 | $14.70 | $757.0K | 141,359 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-07-29 | 2025-07-30 | 807 | $14.00 | $11.3K | 192,859 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-07-28 | 2025-07-30 | 12,946 | $14.04 | $181.8K | 193,666 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2025-07-14 | 2025-07-15 | 6,349 | — | $0 | 88,880 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2025-07-14 | 2025-07-15 | 6,349 | $1.08 | $6.9K | 109,273 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2025-07-14 | 2025-07-15 | 11,366 | $14.59 | $165.8K | 97,907 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-07-11 | 2025-07-15 | 10,758 | $14.45 | $155.5K | 206,612 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2025-07-11 | 2025-07-15 | 15,884 | $14.51 | $230.5K | 846,405 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2025-06-13 | 2025-06-16 | 11,366 | $14.60 | $165.9K | 101,651 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2025-06-12 | 2025-06-16 | 6,348 | — | $0 | 95,229 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2025-06-12 | 2025-06-16 | 6,348 | $1.08 | $6.9K | 113,017 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2025-05-14 | 2025-05-15 | 11,366 | $15.29 | $173.8K | 106,669 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2025-05-12 | 2025-05-13 | 6,349 | — | $0 | 101,577 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2025-05-12 | 2025-05-13 | 6,349 | $1.08 | $6.9K | 118,035 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2025-04-14 | 2025-04-15 | 6,348 | — | $0 | 107,926 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2025-04-14 | 2025-04-15 | 8,400 | $14.83 | $124.6K | 111,686 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2025-04-14 | 2025-04-15 | 2,966 | $13.69 | $40.6K | 120,086 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2025-04-14 | 2025-04-15 | 6,348 | $1.08 | $6.9K | 123,052 | SEC↗ |
| Congleton Jon | Chief Executive Officer | S Sale | 2025-04-11 | 2025-04-15 | 15,319 | $12.19 | $186.7K | 862,289 | SEC↗ |
| Levy Adam Scott | CFO and Secretary | S Sale | 2025-04-11 | 2025-04-15 | 10,757 | $12.06 | $129.7K | 215,340 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2025-04-01 | 2025-04-03 | 1,606 | — | $0 | 114,274 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2025-04-01 | 2025-04-03 | 22,406 | $16.77 | $375.7K | 116,704 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2025-04-01 | 2025-04-03 | 2,791 | $16.02 | $44.7K | 139,110 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | S Sale | 2025-04-01 | 2025-04-03 | 30,574 | $15.00 | $458.6K | 141,901 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2025-04-01 | 2025-04-03 | 1,606 | $1.08 | $1.7K | 172,475 | SEC↗ |
| Slingsby Brian Taylor | Director, 10% Owner | P Buy | 2025-03-13 | 2025-04-25 | 259,259 | $13.50 | $3.50M | 8,903,838 | SEC↗ |
| RA Capital Nexus Fund III, L.P | Director | P Buy | 2025-03-13 | 2025-03-17 | 1,296,296 | $13.50 | $17.50M | 4,280,051 | SEC↗ |
| AKKARAJU SRINIVAS | Director | P Buy | 2025-03-13 | 2025-03-17 | 600,000 | $13.50 | $8.10M | 5,674,916 | SEC↗ |
| Samsara BioCapital, L.P. | 10% Owner | P Buy | 2025-03-13 | 2025-03-17 | 600,000 | $13.50 | $8.10M | 5,674,916 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise deriv | 2025-03-12 | 2025-03-13 | 6,349 | — | $0 | 115,880 | SEC↗ |
| Rodman David Malcom | Chief Medical Officer | M Exercise | 2025-03-12 | 2025-03-13 | 6,349 | $1.08 | $6.9K | 170,869 | SEC↗ |
| SBLENDORIO GLENN | Director | A Award deriv | 2025-02-13 | 2025-02-24 | 32,900 | — | $0 | 32,900 | SEC↗ |
| Karydas Daphne | Director | A Award deriv | 2025-02-13 | 2025-02-24 | 32,900 | — | $0 | 32,900 | SEC↗ |
| Congleton Jon | Chief Executive Officer | A Award deriv | 2025-02-13 | 2025-02-24 | 570,000 | — | $0 | 570,000 | SEC↗ |