Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$0
Insiders on file
47
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Ondrey Aaron | Interim CFO | 8 | $0 | $0 | 2024-01-23 |
| Sandler Alan B. | Chief Medical Officer | 8 | $0 | $0 | 2024-01-23 |
| Cherrington Julie M | Director | 17 | $0 | $686.9K | 2024-01-23 |
| Martinez Maria E | Director | 29 | $0 | $1.53M | 2024-01-23 |
| Hickey Benjamin | EVP, Chief Commercial Officer | 33 | $0 | $1.85M | 2024-01-23 |
| Dissanayake Shehan Bharatha | Other | 13 | $0 | $0 | 2024-01-23 |
| Christensen Jamie | Sr. Vice President, Chief Scie | 144 | $0 | $6.20M | 2024-01-23 |
| BAUM CHARLES M | President,Founder,Head of R&D | 136 | $225.8K | $48.04M | 2024-01-23 |
| Moriarty John B | Chief Legal Officer | 4 | $0 | $0 | 2024-01-23 |
| Davis Aaron I. | Director, 10% Owner | 22 | $0 | $2.38M | 2024-01-23 |
| Sharp Shalini | Director | 11 | $0 | $0 | 2024-01-23 |
| Johnson Craig A | Director | 42 | $0 | $5.61M | 2024-01-23 |
| Hasnain Faheem | Director | 17 | $300.0K | $0 | 2024-01-23 |
| Gallagher Carol Giltner | Director | 6 | $0 | $0 | 2024-01-23 |
| CARTER BRUCE L A | Director | 64 | $0 | $3.95M | 2024-01-23 |
| MVA Investors, LLC | Other | 7 | $35.00M | $0 | 2023-08-11 |
| Boxer Capital, LLC | Other | 35 | $69.20M | $148.67M | 2023-08-11 |
| Stelzer Laurie | Chief Financial Officer | 6 | $0 | $172.2K | 2023-08-09 |
| Meek David D. | Chief Executive Officer | 8 | $0 | $321.3K | 2023-01-20 |
| FUCHS HENRY J | Director | 40 | $0 | $4.81M | 2023-01-20 |
| REED VICKIE S | SVP, Chief Accounting Officer | 14 | $0 | $388.4K | 2022-01-18 |
| Braslyn Ltd. | 10% Owner | 52 | $71.61M | $121.02M | 2021-03-10 |
| LEWIS JOSEPH | 10% Owner | 41 | $0 | $155.80M | 2021-03-05 |
| Faga Daniel | EVP, Chief Operating Officer | 9 | $0 | $828.3K | 2021-02-02 |
| GREY MICHAEL G | Director | 34 | $0 | $3.64M | 2021-01-15 |
| Fuglesang Christopher | 10% Owner | 12 | $15.00M | $80.80M | 2020-10-30 |
| CHEN ISAN | Sr.Vice President, Chief Medi | 35 | $0 | $3.50M | 2020-05-11 |
| Aghazadeh Behzad | 10% Owner | 7 | $18.00M | $75.15M | 2019-07-23 |
| Donadio Jamie A | Vice President, Finance | 27 | $0 | $2.96M | 2019-05-16 |
| Reisman Neil | Director, 10% Owner | 9 | $0 | $0 | 2019-04-04 |
| LEMASTERS CHRISTOPHER C. | EVP, Chief Business Officer | 8 | $0 | $4.31M | 2019-02-14 |
| LAPPE RODNEY W | Director, 10% Owner | 9 | $0 | $0 | 2019-01-17 |
| Boxer Asset Management Inc. | 10% Owner | 7 | $7.50M | $0 | 2018-06-07 |
| venBio Select Advisor LLC | 10% Owner | 3 | $8.45M | $0 | 2017-11-16 |
| Broadfin Capital, LLC | 10% Owner | 1 | $0 | $1.08M | 2017-11-16 |
| BAKER JULIAN | Other | 14 | $25.00M | $9.40M | 2017-11-16 |
| Baker Bros. Advisors (GP) LLC | 10% Owner | 11 | $6.75M | $0 | 2017-11-08 |
| Tuesday Thirteen Inc. | 10% Owner | 1 | $0 | $10.7K | 2017-09-21 |
| RINGO WILLIAM R | Director | 4 | $0 | $0 | 2016-05-18 |
| BAKER FELIX | 10% Owner | 11 | $7.00M | $0 | 2016-03-30 |
| Gergen Mark J | Executive VP, COO | 9 | $0 | $259.2K | 2016-01-22 |
| OrbiMed Capital GP IV LLC | 10% Owner | 1 | $2.00M | $0 | 2015-02-03 |
| BAKER BROS. ADVISORS LP | 10% Owner | 2 | $8.50M | $0 | 2015-01-29 |
| ISALY SAMUEL D | 10% Owner | 6 | $2.19M | $2.33M | 2014-07-01 |
| GODBOUT MARTIN | Director | 4 | $0 | $0 | 2014-03-04 |
| TANG CAPITAL PARTNERS LP | 10% Owner | 1 | $1.00M | $0 | 2013-10-24 |
| TANG KEVIN C | 10% Owner | 2 | $0 | $602.9K | 2013-09-20 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Gallagher Carol Giltner | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 12,784 | — | $0 | 0 | SEC↗ |
| BAUM CHARLES M | Founder, President, and CEO | D To issuer deriv | 2024-01-23 | 2024-01-23 | 1,559 | — | $0 | 0 | SEC↗ |
| BAUM CHARLES M | Founder, President, and CEO | D To issuer deriv | 2024-01-23 | 2024-01-23 | 168,441 | — | $0 | 0 | SEC↗ |
| BAUM CHARLES M | Founder, President, and CEO | D To issuer deriv | 2024-01-23 | 2024-01-23 | 7,520 | — | $0 | 0 | SEC↗ |
| BAUM CHARLES M | Founder, President, and CEO | D To issuer deriv | 2024-01-23 | 2024-01-23 | 178,052 | — | $0 | 0 | SEC↗ |
| BAUM CHARLES M | Founder, President, and CEO | D To issuer deriv | 2024-01-23 | 2024-01-23 | 111,652 | — | $0 | 0 | SEC↗ |
| BAUM CHARLES M | Founder, President, and CEO | D To issuer deriv | 2024-01-23 | 2024-01-23 | 81,458 | — | $0 | 0 | SEC↗ |
| BAUM CHARLES M | Founder, President, and CEO | D To issuer deriv | 2024-01-23 | 2024-01-23 | 69,258 | — | $0 | 0 | SEC↗ |
| BAUM CHARLES M | Founder, President, and CEO | D To issuer deriv | 2024-01-23 | 2024-01-23 | 100,273 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 20,715 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 1,042 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 58,750 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 1,250 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 43,329 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 2,127 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 28,617 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 1,383 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 74,838 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 5,162 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 40,825 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 13,750 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 12,879 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer deriv | 2024-01-23 | 2024-01-23 | 8,747 | — | $0 | 0 | SEC↗ |
| Sandler Alan B. | Chief Medical Officer | D To issuer deriv | 2024-01-23 | 2024-01-23 | 65,000 | — | $0 | 0 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | D To issuer deriv | 2024-01-23 | 2024-01-23 | 43,328 | — | $0 | 0 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | D To issuer deriv | 2024-01-23 | 2024-01-23 | 2,128 | — | $0 | 0 | SEC↗ |
| Ondrey Aaron | Chief Financial Officer | D To issuer deriv | 2024-01-23 | 2024-01-23 | 6,817 | — | $0 | 0 | SEC↗ |
| Ondrey Aaron | Chief Financial Officer | D To issuer deriv | 2024-01-23 | 2024-01-23 | 5,027 | — | $0 | 0 | SEC↗ |
| Ondrey Aaron | Chief Financial Officer | D To issuer deriv | 2024-01-23 | 2024-01-23 | 11,993 | — | $0 | 0 | SEC↗ |
| Hasnain Faheem | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 10,716 | — | $0 | 0 | SEC↗ |
| Hasnain Faheem | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 10,000 | — | $0 | 0 | SEC↗ |
| Hasnain Faheem | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 35,000 | — | $0 | 0 | SEC↗ |
| Johnson Craig A | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 18,000 | — | $0 | 0 | SEC↗ |
| Johnson Craig A | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 10,000 | — | $0 | 0 | SEC↗ |
| Johnson Craig A | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 10,000 | — | $0 | 0 | SEC↗ |
| Johnson Craig A | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 7,520 | — | $0 | 0 | SEC↗ |
| Johnson Craig A | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 11,000 | — | $0 | 0 | SEC↗ |
| CARTER BRUCE L A | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 11,000 | — | $0 | 0 | SEC↗ |
| CARTER BRUCE L A | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 10,000 | — | $0 | 0 | SEC↗ |
| CARTER BRUCE L A | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 7,520 | — | $0 | 0 | SEC↗ |
| Cherrington Julie M | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 7,520 | — | $0 | 0 | SEC↗ |
| Sharp Shalini | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 7,520 | — | $0 | 0 | SEC↗ |
| Davis Aaron I. | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 11,000 | — | $0 | 0 | SEC↗ |
| Davis Aaron I. | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 25,000 | — | $0 | 0 | SEC↗ |
| Davis Aaron I. | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 7,520 | — | $0 | 0 | SEC↗ |
| Martinez Maria E | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 17,500 | — | $0 | 0 | SEC↗ |
| Martinez Maria E | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 7,520 | — | $0 | 0 | SEC↗ |
| Martinez Maria E | Director | D To issuer deriv | 2024-01-23 | 2024-01-23 | 11,000 | — | $0 | 0 | SEC↗ |
| Moriarty John B | Chief Legal Officer | D To issuer deriv | 2024-01-23 | 2024-01-23 | 83,525 | — | $0 | 0 | SEC↗ |
| Dissanayake Shehan Bharatha | Other | D To issuer deriv | 2024-01-23 | 2024-01-25 | 1,413,475 | — | $0 | 0 | SEC↗ |
| Dissanayake Shehan Bharatha | Other | D To issuer deriv | 2024-01-23 | 2024-01-25 | 3,578,036 | — | $0 | 0 | SEC↗ |
| Dissanayake Shehan Bharatha | Other | D To issuer deriv | 2024-01-23 | 2024-01-25 | 332,809 | — | $0 | 0 | SEC↗ |
| Gallagher Carol Giltner | Director | D To issuer | 2024-01-23 | 2024-01-23 | 7,555 | — | $0 | 6,808 | SEC↗ |
| Gallagher Carol Giltner | Director | D To issuer | 2024-01-23 | 2024-01-23 | 6,808 | — | $0 | 0 | SEC↗ |
| BAUM CHARLES M | Founder, President, and CEO | D To issuer | 2024-01-23 | 2024-01-23 | 20,425 | — | $0 | 0 | SEC↗ |
| BAUM CHARLES M | Founder, President, and CEO | D To issuer | 2024-01-23 | 2024-01-23 | 94,057 | — | $0 | 20,425 | SEC↗ |
| BAUM CHARLES M | Founder, President, and CEO | D To issuer | 2024-01-23 | 2024-01-23 | 123,389 | — | $0 | 114,482 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer | 2024-01-23 | 2024-01-23 | 81,480 | — | $0 | 17,021 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer | 2024-01-23 | 2024-01-23 | 56,495 | — | $0 | 98,501 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | D To issuer | 2024-01-23 | 2024-01-23 | 17,021 | — | $0 | 0 | SEC↗ |
| Sandler Alan B. | Chief Medical Officer | D To issuer | 2024-01-23 | 2024-01-23 | 10,547 | — | $0 | 69,318 | SEC↗ |
| Sandler Alan B. | Chief Medical Officer | D To issuer | 2024-01-23 | 2024-01-23 | 17,021 | — | $0 | 0 | SEC↗ |
| Sandler Alan B. | Chief Medical Officer | D To issuer | 2024-01-23 | 2024-01-23 | 52,297 | — | $0 | 17,021 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | D To issuer | 2024-01-23 | 2024-01-23 | 17,021 | — | $0 | 0 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | D To issuer | 2024-01-23 | 2024-01-23 | 72,206 | — | $0 | 17,021 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | D To issuer | 2024-01-23 | 2024-01-23 | 27,801 | — | $0 | 89,227 | SEC↗ |
| Ondrey Aaron | Chief Financial Officer | D To issuer | 2024-01-23 | 2024-01-23 | 17,021 | — | $0 | 0 | SEC↗ |
| Ondrey Aaron | Chief Financial Officer | D To issuer | 2024-01-23 | 2024-01-23 | 1,302 | — | $0 | 38,159 | SEC↗ |
| Ondrey Aaron | Chief Financial Officer | D To issuer | 2024-01-23 | 2024-01-23 | 21,138 | — | $0 | 17,021 | SEC↗ |
| Hasnain Faheem | Director | D To issuer | 2024-01-23 | 2024-01-23 | 8,717 | — | $0 | 16,035 | SEC↗ |
| Hasnain Faheem | Director | D To issuer | 2024-01-23 | 2024-01-23 | 9,702 | — | $0 | 0 | SEC↗ |
| Hasnain Faheem | Director | D To issuer | 2024-01-23 | 2024-01-23 | 6,333 | — | $0 | 9,702 | SEC↗ |
| Johnson Craig A | Director | D To issuer | 2024-01-23 | 2024-01-23 | 6,021 | — | $0 | 11,252 | SEC↗ |
| Johnson Craig A | Director | D To issuer | 2024-01-23 | 2024-01-23 | 4,444 | — | $0 | 6,808 | SEC↗ |
| Johnson Craig A | Director | D To issuer | 2024-01-23 | 2024-01-23 | 6,808 | — | $0 | 0 | SEC↗ |
| CARTER BRUCE L A | Director | D To issuer | 2024-01-23 | 2024-01-23 | 6,021 | — | $0 | 11,252 | SEC↗ |
| CARTER BRUCE L A | Director | D To issuer | 2024-01-23 | 2024-01-23 | 4,444 | — | $0 | 6,808 | SEC↗ |
| CARTER BRUCE L A | Director | D To issuer | 2024-01-23 | 2024-01-23 | 6,808 | — | $0 | 0 | SEC↗ |
| Cherrington Julie M | Director | D To issuer | 2024-01-23 | 2024-01-23 | 4,444 | — | $0 | 6,808 | SEC↗ |
| Cherrington Julie M | Director | D To issuer | 2024-01-23 | 2024-01-23 | 6,808 | — | $0 | 0 | SEC↗ |
| Sharp Shalini | Director | D To issuer | 2024-01-23 | 2024-01-23 | 4,162 | — | $0 | 12,060 | SEC↗ |
| Sharp Shalini | Director | D To issuer | 2024-01-23 | 2024-01-23 | 5,252 | — | $0 | 6,808 | SEC↗ |
| Sharp Shalini | Director | D To issuer | 2024-01-23 | 2024-01-23 | 6,808 | — | $0 | 0 | SEC↗ |
| Davis Aaron I. | Director | D To issuer | 2024-01-23 | 2024-01-23 | 4,444 | — | $0 | 6,808 | SEC↗ |
| Davis Aaron I. | Director | D To issuer | 2024-01-23 | 2024-01-23 | 43,073 | — | $0 | 11,252 | SEC↗ |
| Davis Aaron I. | Director | D To issuer | 2024-01-23 | 2024-01-23 | 6,808 | — | $0 | 0 | SEC↗ |
| Martinez Maria E | Director | D To issuer | 2024-01-23 | 2024-01-23 | 6,808 | — | $0 | 0 | SEC↗ |
| Martinez Maria E | Director | D To issuer | 2024-01-23 | 2024-01-23 | 4,444 | — | $0 | 6,808 | SEC↗ |
| Martinez Maria E | Director | D To issuer | 2024-01-23 | 2024-01-23 | 6,021 | — | $0 | 11,252 | SEC↗ |
| Moriarty John B | Chief Legal Officer | D To issuer | 2024-01-23 | 2024-01-23 | 71,660 | — | $0 | 0 | SEC↗ |
| Moriarty John B | Chief Legal Officer | D To issuer | 2024-01-23 | 2024-01-23 | 675 | — | $0 | 71,660 | SEC↗ |
| Dissanayake Shehan Bharatha | Other | D To issuer | 2024-01-23 | 2024-01-25 | 287,866 | — | $0 | 0 | SEC↗ |
| Dissanayake Shehan Bharatha | Other | D To issuer | 2024-01-23 | 2024-01-25 | 30,518 | — | $0 | 0 | SEC↗ |
| Dissanayake Shehan Bharatha | Other | D To issuer | 2024-01-23 | 2024-01-25 | 3,201,440 | — | $0 | 0 | SEC↗ |
| Dissanayake Shehan Bharatha | Other | D To issuer | 2024-01-23 | 2024-01-25 | 203,754 | — | $0 | 0 | SEC↗ |
| Dissanayake Shehan Bharatha | Other | D To issuer | 2024-01-23 | 2024-01-25 | 3,135,966 | — | $0 | 0 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | S Sale | 2024-01-16 | 2024-01-18 | 631 | $59.02 | $37.2K | 155,927 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | S Sale | 2024-01-16 | 2024-01-18 | 966 | $59.02 | $57.0K | 156,558 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2024-01-16 | 2024-01-18 | 631 | $59.02 | $37.2K | 117,028 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2024-01-16 | 2024-01-18 | 966 | $59.02 | $57.0K | 117,659 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2024-01-08 | 2024-01-09 | 2,090 | $58.92 | $123.1K | 118,625 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | S Sale | 2024-01-04 | 2024-01-05 | 1,531 | $58.81 | $90.0K | 157,135 | SEC↗ |
| BAUM CHARLES M | Interim CEO | A Award | 2023-12-29 | 2024-01-03 | 20,425 | $58.75 | $1.20M | 247,700 | SEC↗ |
| Ondrey Aaron | CFO | A Award | 2023-12-29 | 2024-01-03 | 17,021 | $58.75 | $1000.0K | 39,461 | SEC↗ |
| Sandler Alan B. | Chief Medical Officer | A Award | 2023-12-29 | 2024-01-03 | 17,021 | $58.75 | $1000.0K | 79,318 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | A Award | 2023-12-29 | 2024-01-03 | 17,021 | $58.75 | $1000.0K | 158,666 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | A Award | 2023-12-29 | 2024-01-03 | 17,021 | $58.75 | $1000.0K | 120,715 | SEC↗ |
| CARTER BRUCE L A | Director | A Award | 2023-12-29 | 2024-01-03 | 6,808 | $58.75 | $400.0K | 17,273 | SEC↗ |
| Hasnain Faheem | Director | A Award | 2023-12-29 | 2024-01-03 | 9,702 | $58.75 | $570.0K | 24,752 | SEC↗ |
| Cherrington Julie M | Director | A Award | 2023-12-29 | 2024-01-03 | 6,808 | $58.75 | $400.0K | 11,252 | SEC↗ |
| Sharp Shalini | Director | A Award | 2023-12-29 | 2024-01-03 | 6,808 | $58.75 | $400.0K | 16,222 | SEC↗ |
| Gallagher Carol Giltner | Director | A Award | 2023-12-29 | 2024-01-03 | 6,808 | $58.75 | $400.0K | 14,363 | SEC↗ |
| Martinez Maria E | Director | A Award | 2023-12-29 | 2024-01-03 | 6,808 | $58.75 | $400.0K | 17,273 | SEC↗ |
| Johnson Craig A | Director | A Award | 2023-12-29 | 2024-01-03 | 6,808 | $58.75 | $400.0K | 17,273 | SEC↗ |
| Davis Aaron I. | Director | A Award | 2023-12-29 | 2024-01-03 | 6,808 | $58.75 | $400.0K | 54,325 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | S Sale | 2023-12-18 | 2023-12-19 | 2,387 | $57.50 | $137.3K | 141,645 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2023-12-13 | 2023-12-14 | 2,220 | $56.67 | $125.8K | 103,694 | SEC↗ |
| Ondrey Aaron | Interim CFO | A Award | 2023-09-08 | 2023-09-12 | 8,412 | $35.66 | $300.0K | 22,440 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | S Sale | 2023-09-08 | 2023-09-12 | 2,388 | $35.63 | $85.1K | 144,032 | SEC↗ |
| Hasnain Faheem | Director | P Buy | 2023-08-11 | 2023-08-14 | 10,791 | $27.80 | $300.0K | 10,791 | SEC↗ |
| MVA Investors, LLC | Other | P Buy | 2023-08-11 | 2023-08-15 | 57,533 | $27.80 | $1.60M | 287,866 | SEC↗ |
| MVA Investors, LLC | Other | P Buy | 2023-08-11 | 2023-08-15 | 1,201,440 | $27.80 | $33.40M | 3,201,440 | SEC↗ |
| Boxer Capital, LLC | Other | P Buy | 2023-08-11 | 2023-08-15 | 1,201,440 | $27.80 | $33.40M | 3,201,440 | SEC↗ |
| Boxer Capital, LLC | Other | P Buy | 2023-08-11 | 2023-08-15 | 57,533 | $27.80 | $1.60M | 287,866 | SEC↗ |
| Sandler Alan B. | Chief Medical Officer | A Award | 2023-08-09 | 2023-08-10 | 22,297 | $37.00 | $825.0K | 62,297 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | A Award | 2023-08-09 | 2023-08-10 | 22,297 | $37.00 | $825.0K | 146,420 | SEC↗ |
| Moriarty John B | Chief Legal Officer | A Award | 2023-08-09 | 2023-08-10 | 22,297 | $37.00 | $825.0K | 71,660 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | A Award | 2023-08-09 | 2023-08-10 | 22,297 | $37.00 | $825.0K | 105,914 | SEC↗ |
| BAUM CHARLES M | Interim CEO | A Award | 2023-08-09 | 2023-08-10 | 54,054 | $37.00 | $2.00M | 227,275 | SEC↗ |
| Stelzer Laurie | Chief Financial Officer | A Award | 2023-08-09 | 2023-08-10 | 22,297 | $37.00 | $825.0K | 102,312 | SEC↗ |
| Gallagher Carol Giltner | Director | A Award deriv | 2023-06-22 | 2023-06-23 | 12,784 | — | $0 | 12,784 | SEC↗ |
| Gallagher Carol Giltner | Director | A Award | 2023-06-22 | 2023-06-23 | 7,555 | — | $0 | 7,555 | SEC↗ |
| Stelzer Laurie | Chief Financial Officer | S Sale | 2023-06-02 | 2023-06-02 | 4,647 | $37.06 | $172.2K | 80,015 | SEC↗ |
| Christensen Jamie | EVP & Chief Scientific Offic | S Sale | 2023-05-24 | 2023-05-24 | 619 | $45.29 | $28.0K | 124,123 | SEC↗ |
| Sharp Shalini | Director | A Award deriv | 2023-01-20 | 2023-01-24 | 7,520 | — | $0 | 7,520 | SEC↗ |
| Martinez Maria E | Director | A Award deriv | 2023-01-20 | 2023-01-24 | 7,520 | — | $0 | 7,520 | SEC↗ |
| CARTER BRUCE L A | Director | A Award deriv | 2023-01-20 | 2023-01-24 | 7,520 | — | $0 | 7,520 | SEC↗ |
| FUCHS HENRY J | Director | A Award deriv | 2023-01-20 | 2023-01-24 | 7,520 | — | $0 | 7,520 | SEC↗ |
| Meek David D. | Chief Executive Officer | A Award deriv | 2023-01-20 | 2023-01-24 | 151,233 | — | $0 | 151,233 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | A Award deriv | 2023-01-20 | 2023-01-24 | 45,456 | — | $0 | 45,456 | SEC↗ |
| Stelzer Laurie | CFO | A Award deriv | 2023-01-20 | 2023-01-24 | 45,456 | — | $0 | 45,456 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | A Award deriv | 2023-01-20 | 2023-01-24 | 45,456 | — | $0 | 45,456 | SEC↗ |
| Hasnain Faheem | Director | A Award deriv | 2023-01-20 | 2023-01-24 | 10,716 | — | $0 | 10,716 | SEC↗ |
| Cherrington Julie M | Director | A Award deriv | 2023-01-20 | 2023-01-24 | 7,520 | — | $0 | 7,520 | SEC↗ |
| Johnson Craig A | Director | A Award deriv | 2023-01-20 | 2023-01-24 | 7,520 | — | $0 | 7,520 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | A Award deriv | 2023-01-20 | 2023-01-24 | 7,520 | — | $0 | 7,520 | SEC↗ |
| Davis Aaron I. | Director, 10% Owner | A Award deriv | 2023-01-20 | 2023-01-24 | 7,520 | — | $0 | 7,520 | SEC↗ |
| Sharp Shalini | Director | A Award | 2023-01-20 | 2023-01-24 | 4,444 | — | $0 | 9,414 | SEC↗ |
| Martinez Maria E | Director | A Award | 2023-01-20 | 2023-01-24 | 4,444 | — | $0 | 10,465 | SEC↗ |
| CARTER BRUCE L A | Director | A Award | 2023-01-20 | 2023-01-24 | 4,444 | — | $0 | 10,465 | SEC↗ |
| FUCHS HENRY J | Director | A Award | 2023-01-20 | 2023-01-24 | 4,444 | — | $0 | 10,465 | SEC↗ |
| Meek David D. | Chief Executive Officer | A Award | 2023-01-20 | 2023-01-24 | 89,379 | — | $0 | 151,171 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | A Award | 2023-01-20 | 2023-01-24 | 26,864 | — | $0 | 124,742 | SEC↗ |
| Stelzer Laurie | CFO | A Award | 2023-01-20 | 2023-01-24 | 26,864 | — | $0 | 84,662 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | A Award | 2023-01-20 | 2023-01-24 | 36,394 | — | $0 | 83,617 | SEC↗ |
| Hasnain Faheem | Director | A Award | 2023-01-20 | 2023-01-24 | 6,333 | — | $0 | 15,050 | SEC↗ |
| Cherrington Julie M | Director | A Award | 2023-01-20 | 2023-01-24 | 4,444 | — | $0 | 4,444 | SEC↗ |
| Johnson Craig A | Director | A Award | 2023-01-20 | 2023-01-24 | 4,444 | — | $0 | 10,465 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | A Award | 2023-01-20 | 2023-01-24 | 4,444 | — | $0 | 173,221 | SEC↗ |
| Davis Aaron I. | Director, 10% Owner | A Award | 2023-01-20 | 2023-01-24 | 4,444 | — | $0 | 47,517 | SEC↗ |
| Cherrington Julie M | Director | S Sale | 2023-01-18 | 2023-01-20 | 2,546 | $44.66 | $113.7K | 0 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2023-01-17 | 2023-01-19 | 619 | $42.38 | $26.2K | 47,223 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2023-01-17 | 2023-01-19 | 947 | $42.38 | $40.1K | 47,842 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | S Sale | 2023-01-17 | 2023-01-19 | 1,358 | $42.38 | $57.6K | 98,765 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | S Sale | 2023-01-17 | 2023-01-19 | 887 | $42.38 | $37.6K | 97,878 | SEC↗ |
| Meek David D. | Chief Executive Officer | S Sale | 2023-01-17 | 2023-01-19 | 3,179 | $42.38 | $134.7K | 61,792 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2023-01-09 | 2023-01-10 | 2,088 | $45.37 | $94.7K | 48,789 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | S Sale | 2023-01-04 | 2023-01-05 | 1,949 | $46.60 | $90.8K | 100,123 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | S Sale | 2023-01-04 | 2023-01-05 | 3,648 | $46.60 | $170.0K | 168,777 | SEC↗ |
| Meek David D. | Chief Executive Officer | S Sale | 2022-12-21 | 2022-12-21 | 4,616 | $40.41 | $186.5K | 64,971 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2022-12-21 | 2022-12-21 | 3,248 | $40.41 | $131.3K | 50,877 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | S Sale | 2022-12-21 | 2022-12-21 | 9,092 | $40.42 | $367.5K | 172,425 | SEC↗ |
| Meek David D. | Chief Executive Officer | A Award | 2022-12-19 | 2022-12-21 | 35,425 | — | $0 | 69,587 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | A Award | 2022-12-19 | 2022-12-21 | 19,149 | — | $0 | 54,125 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | A Award | 2022-12-19 | 2022-12-21 | 53,618 | — | $0 | 181,517 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | S Sale | 2022-12-16 | 2022-12-20 | 2,410 | $43.00 | $103.6K | 102,072 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | S Sale | 2022-12-02 | 2022-12-05 | 1,726 | $90.19 | $155.7K | 104,482 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | M Exercise deriv | 2022-11-28 | 2022-11-28 | 69,256 | — | $0 | 69,258 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | S Sale | 2022-11-28 | 2022-11-28 | 69,256 | $100.00 | $6.93M | 127,899 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | M Exercise | 2022-11-28 | 2022-11-28 | 69,256 | $17.41 | $1.21M | 197,155 | SEC↗ |
| Sandler Alan B. | Chief Medical Officer | A Award deriv | 2022-11-07 | 2022-11-08 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Sandler Alan B. | Chief Medical Officer | A Award | 2022-11-07 | 2022-11-08 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | A Award | 2022-09-07 | 2022-09-09 | 19,149 | — | $0 | 106,089 | SEC↗ |
| CARTER BRUCE L A | Director | M Exercise deriv | 2022-08-12 | 2022-08-16 | 10,000 | — | $0 | 0 | SEC↗ |
| CARTER BRUCE L A | Director | M Exercise | 2022-08-12 | 2022-08-16 | 10,000 | $27.00 | $270.0K | 16,021 | SEC↗ |
| CARTER BRUCE L A | Director | S Sale | 2022-08-12 | 2022-08-16 | 5,107 | $85.04 | $434.3K | 10,914 | SEC↗ |
| CARTER BRUCE L A | Director | S Sale | 2022-08-12 | 2022-08-16 | 4,893 | $85.96 | $420.6K | 6,021 | SEC↗ |
| Stelzer Laurie | CFO | A Award deriv | 2022-06-01 | 2022-06-03 | 91,164 | — | $0 | 91,164 | SEC↗ |
| Stelzer Laurie | CFO | A Award | 2022-06-01 | 2022-06-03 | 57,798 | — | $0 | 57,798 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | S Sale | 2022-05-23 | 2022-06-14 | 624 | $63.54 | $39.6K | 86,804 | SEC↗ |
| FUCHS HENRY J | Director | M Exercise deriv | 2022-02-11 | 2022-02-14 | 5,000 | — | $0 | 0 | SEC↗ |
| FUCHS HENRY J | Director | M Exercise deriv | 2022-02-11 | 2022-02-14 | 6,000 | — | $0 | 0 | SEC↗ |
| FUCHS HENRY J | Director | M Exercise | 2022-02-11 | 2022-02-14 | 6,000 | $20.54 | $123.2K | 12,021 | SEC↗ |
| FUCHS HENRY J | Director | S Sale | 2022-02-11 | 2022-02-14 | 2,090 | $104.76 | $218.9K | 14,931 | SEC↗ |
| FUCHS HENRY J | Director | M Exercise | 2022-02-11 | 2022-02-14 | 5,000 | $20.54 | $102.7K | 17,021 | SEC↗ |
| FUCHS HENRY J | Director | S Sale | 2022-02-11 | 2022-02-14 | 8,700 | $105.80 | $920.5K | 6,231 | SEC↗ |
| FUCHS HENRY J | Director | S Sale | 2022-02-11 | 2022-02-14 | 210 | $106.34 | $22.3K | 6,021 | SEC↗ |
| Cherrington Julie M | Director | S Sale | 2022-01-19 | 2022-01-20 | 1,475 | $116.07 | $171.2K | 2,546 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | M Exercise deriv | 2022-01-18 | 2022-01-18 | 3,703 | — | $0 | 178,052 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2022-01-18 | 2022-01-18 | 627 | $120.48 | $75.5K | 34,976 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | M Exercise | 2022-01-18 | 2022-01-18 | 3,703 | $27.00 | $100.0K | 130,416 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | S Sale | 2022-01-18 | 2022-01-18 | 2,517 | $120.48 | $303.2K | 127,899 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | S Sale | 2022-01-18 | 2022-01-18 | 627 | $120.51 | $75.6K | 87,428 | SEC↗ |
| REED VICKIE S | SVP, Chief Accounting Offic | S Sale | 2022-01-18 | 2022-01-18 | 533 | $120.48 | $64.2K | 15,369 | SEC↗ |
| Sharp Shalini | Director | A Award deriv | 2022-01-14 | 2022-01-18 | 3,688 | — | $0 | 3,688 | SEC↗ |
| Davis Aaron I. | Director, 10% Owner | A Award deriv | 2022-01-14 | 2022-01-18 | 3,688 | — | $0 | 3,688 | SEC↗ |
| Cherrington Julie M | Director | A Award deriv | 2022-01-14 | 2022-01-18 | 3,688 | — | $0 | 3,688 | SEC↗ |
| Meek David D. | Chief Executive Officer | A Award deriv | 2022-01-14 | 2022-01-18 | 56,433 | — | $0 | 56,433 | SEC↗ |
| Martinez Maria E | Director | A Award deriv | 2022-01-14 | 2022-01-18 | 3,688 | — | $0 | 3,688 | SEC↗ |
| Johnson Craig A | Director | A Award deriv | 2022-01-14 | 2022-01-18 | 3,688 | — | $0 | 3,688 | SEC↗ |
| FUCHS HENRY J | Director | A Award deriv | 2022-01-14 | 2022-01-18 | 3,688 | — | $0 | 3,688 | SEC↗ |
| CARTER BRUCE L A | Director | A Award deriv | 2022-01-14 | 2022-01-18 | 3,688 | — | $0 | 3,688 | SEC↗ |
| Hasnain Faheem | Director | A Award deriv | 2022-01-14 | 2022-01-18 | 5,243 | — | $0 | 5,243 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | A Award deriv | 2022-01-14 | 2022-01-18 | 17,821 | — | $0 | 17,821 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | A Award deriv | 2022-01-14 | 2022-01-18 | 42,325 | — | $0 | 42,325 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | A Award deriv | 2022-01-14 | 2022-01-18 | 17,821 | — | $0 | 17,821 | SEC↗ |
| REED VICKIE S | SVP, Chief Accounting Offic | A Award deriv | 2022-01-14 | 2022-01-18 | 8,910 | — | $0 | 8,910 | SEC↗ |
| Sharp Shalini | Director | A Award | 2022-01-14 | 2022-01-18 | 2,546 | — | $0 | 4,970 | SEC↗ |
| Davis Aaron I. | Director, 10% Owner | A Award | 2022-01-14 | 2022-01-18 | 2,546 | — | $0 | 43,073 | SEC↗ |
| Cherrington Julie M | Director | A Award | 2022-01-14 | 2022-01-18 | 2,546 | — | $0 | 4,021 | SEC↗ |
| Meek David D. | Chief Executive Officer | A Award | 2022-01-14 | 2022-01-18 | 34,057 | — | $0 | 34,057 | SEC↗ |
| Martinez Maria E | Director | A Award | 2022-01-14 | 2022-01-18 | 2,546 | — | $0 | 6,021 | SEC↗ |
| Johnson Craig A | Director | A Award | 2022-01-14 | 2022-01-18 | 2,546 | — | $0 | 6,021 | SEC↗ |
| FUCHS HENRY J | Director | A Award | 2022-01-14 | 2022-01-18 | 2,546 | — | $0 | 6,021 | SEC↗ |
| CARTER BRUCE L A | Director | A Award | 2022-01-14 | 2022-01-18 | 2,546 | — | $0 | 6,021 | SEC↗ |
| Hasnain Faheem | Director | A Award | 2022-01-14 | 2022-01-18 | 3,619 | — | $0 | 8,717 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | A Award | 2022-01-14 | 2022-01-18 | 10,755 | — | $0 | 35,603 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | A Award | 2022-01-14 | 2022-01-18 | 25,543 | — | $0 | 126,713 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | A Award | 2022-01-14 | 2022-01-18 | 10,755 | — | $0 | 88,055 | SEC↗ |
| REED VICKIE S | SVP, Chief Accounting Offic | A Award | 2022-01-14 | 2022-01-18 | 5,377 | — | $0 | 15,902 | SEC↗ |
| REED VICKIE S | SVP, Chief Accounting Offic | S Sale | 2022-01-07 | 2022-01-07 | 345 | $135.94 | $46.9K | 10,525 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2022-01-07 | 2022-01-07 | 1,964 | $135.94 | $267.0K | 24,848 | SEC↗ |
| REED VICKIE S | SVP, Chief Accounting Offic | S Sale | 2022-01-04 | 2022-01-06 | 758 | $147.74 | $112.0K | 10,870 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | S Sale | 2022-01-04 | 2022-01-06 | 1,442 | $147.72 | $213.0K | 77,300 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | S Sale | 2022-01-04 | 2022-01-06 | 69 | $149.09 | $10.3K | 101,170 | SEC↗ |
| BAUM CHARLES M | President,Founder,Head of R& | S Sale | 2022-01-04 | 2022-01-06 | 4,045 | $147.73 | $597.6K | 101,239 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | A Award | 2021-12-16 | 2021-12-17 | 19,149 | — | $0 | 78,742 | SEC↗ |
| BAUM CHARLES M | President & CEO | G Gift | 2021-12-16 | 2021-12-17 | 7,430 | — | $0 | 105,284 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | S Sale | 2021-12-06 | 2021-12-07 | 9 | $132.00 | $1.2K | 59,505 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | S Sale | 2021-12-06 | 2021-12-07 | 1,192 | $130.78 | $155.9K | 59,514 | SEC↗ |
| BAUM CHARLES M | President & Head of R&D | M Exercise deriv | 2021-12-03 | 2021-12-03 | 47,204 | — | $0 | 0 | SEC↗ |
| BAUM CHARLES M | President & Head of R&D | S Sale | 2021-12-03 | 2021-12-03 | 3,900 | $133.27 | $519.8K | 125,309 | SEC↗ |
| BAUM CHARLES M | President & Head of R&D | S Sale | 2021-12-03 | 2021-12-03 | 1,210 | $136.66 | $165.4K | 113,699 | SEC↗ |
| BAUM CHARLES M | President & Head of R&D | S Sale | 2021-12-03 | 2021-12-03 | 6,558 | $135.64 | $889.5K | 114,909 | SEC↗ |
| BAUM CHARLES M | President & Head of R&D | S Sale | 2021-12-03 | 2021-12-03 | 3,842 | $134.57 | $517.0K | 121,467 | SEC↗ |
| BAUM CHARLES M | President & Head of R&D | S Sale | 2021-12-03 | 2021-12-03 | 985 | $137.56 | $135.5K | 112,714 | SEC↗ |
| BAUM CHARLES M | President & Head of R&D | S Sale | 2021-12-03 | 2021-12-03 | 21,509 | $132.49 | $2.85M | 129,209 | SEC↗ |
| BAUM CHARLES M | President & Head of R&D | S Sale | 2021-12-03 | 2021-12-03 | 9,200 | $131.61 | $1.21M | 150,718 | SEC↗ |
| BAUM CHARLES M | President & Head of R&D | M Exercise | 2021-12-03 | 2021-12-03 | 47,204 | $8.49 | $400.8K | 159,918 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | A Award | 2021-12-03 | 2021-12-07 | 6,856 | — | $0 | 60,706 | SEC↗ |
| Meek David D. | Chief Executive Officer | A Award deriv | 2021-09-22 | 2021-09-24 | 150,300 | — | $0 | 150,300 | SEC↗ |
| BAUM CHARLES M | President & CEO | M Exercise deriv | 2021-06-18 | 2021-06-21 | 40,000 | — | $0 | 47,204 | SEC↗ |
| BAUM CHARLES M | President & CEO | S Sale | 2021-06-18 | 2021-06-21 | 1,023 | $166.73 | $170.6K | 112,714 | SEC↗ |
| BAUM CHARLES M | President & CEO | M Exercise | 2021-06-18 | 2021-06-21 | 40,000 | $8.49 | $339.6K | 152,714 | SEC↗ |
| BAUM CHARLES M | President & CEO | S Sale | 2021-06-18 | 2021-06-21 | 4,816 | $164.07 | $790.2K | 147,898 | SEC↗ |
| BAUM CHARLES M | President & CEO | S Sale | 2021-06-18 | 2021-06-21 | 13,338 | $164.90 | $2.20M | 134,560 | SEC↗ |
| BAUM CHARLES M | President & CEO | S Sale | 2021-06-18 | 2021-06-21 | 20,823 | $166.07 | $3.46M | 113,737 | SEC↗ |
| Christensen Jamie | EVP, Chief Scientific Office | S Sale | 2021-05-24 | 2021-05-25 | 435 | $154.34 | $67.1K | 53,850 | SEC↗ |
| CARTER BRUCE L A | Director | M Exercise deriv | 2021-04-05 | 2021-04-06 | 2,250 | — | $0 | 0 | SEC↗ |
| CARTER BRUCE L A | Director | M Exercise | 2021-04-05 | 2021-04-06 | 2,250 | $6.78 | $15.3K | 5,725 | SEC↗ |
| CARTER BRUCE L A | Director | S Sale | 2021-04-05 | 2021-04-06 | 1,968 | $176.70 | $347.7K | 3,757 | SEC↗ |
| CARTER BRUCE L A | Director | S Sale | 2021-04-05 | 2021-04-06 | 282 | $180.00 | $50.8K | 3,475 | SEC↗ |
| Sharp Shalini | Director | A Award deriv | 2021-03-26 | 2021-03-30 | 3,523 | — | $0 | 3,523 | SEC↗ |
| Sharp Shalini | Director | A Award | 2021-03-26 | 2021-03-30 | 2,424 | — | $0 | 2,424 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | M Exercise deriv | 2021-03-19 | 2021-03-22 | 2,369 | — | $0 | 30,116 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2021-03-19 | 2021-03-22 | 588 | $175.54 | $103.2K | 28,593 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2021-03-19 | 2021-03-22 | 1,350 | $176.42 | $238.2K | 27,243 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | S Sale | 2021-03-19 | 2021-03-22 | 431 | $177.71 | $76.6K | 26,812 | SEC↗ |
| Hickey Benjamin | EVP, Chief Commercial Office | M Exercise | 2021-03-19 | 2021-03-22 | 2,369 | $114.33 | $270.8K | 29,181 | SEC↗ |
| Braslyn Ltd. | 10% Owner | S Sale | 2021-03-10 | 2021-03-10 | 189 | $195.52 | $37.0K | 3,135,777 | SEC↗ |
| Braslyn Ltd. | 10% Owner | S Sale | 2021-03-10 | 2021-03-10 | 1 | $195.90 | $196 | 3,135,966 | SEC↗ |
| Braslyn Ltd. | 10% Owner | M Exercise | 2021-03-10 | 2021-03-10 | 410 | — | $0 | 3,135,967 | SEC↗ |
| Braslyn Ltd. | 10% Owner | S Sale | 2021-03-10 | 2021-03-10 | 200 | $198.00 | $39.6K | 3,135,557 | SEC↗ |
| Braslyn Ltd. | 10% Owner | S Sale | 2021-03-10 | 2021-03-10 | 20 | $196.12 | $3.9K | 3,135,757 | SEC↗ |
| Braslyn Ltd. | 10% Owner | S Sale | 2021-03-09 | 2021-03-10 | 1,107 | $195.82 | $216.8K | 3,134,859 | SEC↗ |
| Braslyn Ltd. | 10% Owner | S Sale | 2021-03-09 | 2021-03-10 | 4,633 | $197.30 | $914.1K | 3,130,226 | SEC↗ |
| Braslyn Ltd. | 10% Owner | S Sale | 2021-03-09 | 2021-03-10 | 1 | $191.00 | $191 | 3,135,966 | SEC↗ |
| Braslyn Ltd. | 10% Owner | M Exercise | 2021-03-09 | 2021-03-10 | 11,971 | — | $0 | 3,135,967 | SEC↗ |
| Braslyn Ltd. | 10% Owner | S Sale | 2021-03-09 | 2021-03-10 | 2,237 | $199.08 | $445.3K | 3,123,996 | SEC↗ |
| Braslyn Ltd. | 10% Owner | S Sale | 2021-03-09 | 2021-03-10 | 3,993 | $197.81 | $789.9K | 3,126,233 | SEC↗ |
| LEWIS JOSEPH | 10% Owner | M Exercise deriv | 2021-03-05 | 2021-03-09 | 468,639 | $13.00 | $6.09M | 332,809 | SEC↗ |
| LEWIS JOSEPH | 10% Owner | M Exercise deriv | 2021-03-05 | 2021-03-09 | 128,805 | $5.60 | $721.3K | 0 | SEC↗ |
| LEWIS JOSEPH | 10% Owner | M Exercise deriv | 2021-03-05 | 2021-03-09 | 13,996 | $5.60 | $78.4K | 0 | SEC↗ |
| LEWIS JOSEPH | 10% Owner | S Sale | 2021-03-05 | 2021-03-09 | 4 | $181.00 | $724 | 2,363,000 | SEC↗ |
| LEWIS JOSEPH | 10% Owner | M Exercise | 2021-03-05 | 2021-03-09 | 13,996 | — | $0 | 267,334 | SEC↗ |
| LEWIS JOSEPH | 10% Owner | S Sale | 2021-03-05 | 2021-03-09 | 363,000 | $181.15 | $65.76M | 2,000,000 | SEC↗ |
| LEWIS JOSEPH | 10% Owner | S Sale | 2021-03-05 | 2021-03-09 | 1 | $181.00 | $181 | 267,333 | SEC↗ |
| LEWIS JOSEPH | 10% Owner | M Exercise | 2021-03-05 | 2021-03-09 | 597,444 | — | $0 | 2,363,004 | SEC↗ |
| LEWIS JOSEPH | 10% Owner | S Sale | 2021-03-05 | 2021-03-09 | 37,000 | $181.15 | $6.70M | 230,333 | SEC↗ |
| Cherrington Julie M | Director | S Sale | 2021-03-02 | 2021-03-04 | 10 | $203.00 | $2.0K | 1,475 | SEC↗ |
| Cherrington Julie M | Director | S Sale | 2021-03-02 | 2021-03-04 | 1,990 | $201.00 | $400.0K | 1,485 | SEC↗ |
| CARTER BRUCE L A | Director | M Exercise deriv | 2021-02-02 | 2021-02-03 | 2,250 | — | $0 | 2,250 | SEC↗ |
| Faga Daniel | EVP, Chief Operating Officer | M Exercise deriv | 2021-02-02 | 2021-02-03 | 1,340 | — | $0 | 63,630 | SEC↗ |
| CARTER BRUCE L A | Director | S Sale | 2021-02-02 | 2021-02-03 | 300 | $192.32 | $57.7K | 3,693 | SEC↗ |
| CARTER BRUCE L A | Director | S Sale | 2021-02-02 | 2021-02-03 | 1,732 | $190.50 | $329.9K | 3,993 | SEC↗ |
| CARTER BRUCE L A | Director | M Exercise | 2021-02-02 | 2021-02-03 | 2,250 | $6.78 | $15.3K | 5,725 | SEC↗ |
| CARTER BRUCE L A | Director | S Sale | 2021-02-02 | 2021-02-03 | 218 | $194.38 | $42.4K | 3,475 | SEC↗ |
| Faga Daniel | EVP, Chief Operating Officer | M Exercise | 2021-02-02 | 2021-02-03 | 1,340 | $114.33 | $153.2K | 31,978 | SEC↗ |
| Faga Daniel | EVP, Chief Operating Officer | S Sale | 2021-02-02 | 2021-02-03 | 1,340 | $194.38 | $260.5K | 30,638 | SEC↗ |
| Martinez Maria E | Director | M Exercise deriv | 2021-01-29 | 2021-02-01 | 7,500 | — | $0 | 17,500 | SEC↗ |