Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$0
Insiders on file
23
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Silva Karen | Principal Accounting Officer | 3 | $0 | $0 | 2025-02-19 |
| Strange Kevin T | Chief Financial Officer | 17 | $0 | $0 | 2025-02-19 |
| Warner Robert Keith | Director | 6 | $0 | $0 | 2025-02-19 |
| Chambers Rebecca | Director | 7 | $0 | $55.7K | 2025-02-19 |
| Hykes Andrew | President and CEO | 214 | $107.3K | $34.20M | 2025-02-19 |
| Tu Thomas | Chief Medical Officer | 196 | $533.7K | $16.75M | 2025-02-19 |
| Szyman Catherine M. | Director | 9 | $533.7K | $0 | 2025-02-19 |
| Lucchese Cynthia L | Director | 8 | $533.7K | $0 | 2025-02-19 |
| Hoffman William | President and CEO | 390 | $248.8K | $189.44M | 2025-02-19 |
| MILDER DONALD B | Director, 10% Owner | 106 | $10.55M | $14.56M | 2025-02-19 |
| ROOT JONATHAN D | Director, 10% Owner | 41 | $4.81M | $0 | 2025-02-19 |
| Mead Dana G Jr. | Director | 6 | $0 | $0 | 2025-02-19 |
| Hill, Mitch C. | Chief Financial Officer | 296 | $172.9K | $26.00M | 2024-10-01 |
| Nielsen Kirk G. | Director, 10% Owner | 40 | $0 | $24.7K | 2023-05-27 |
| Presidio Management Group X LLC | 10% Owner | 6 | $0 | $0 | 2021-03-16 |
| Cooperatieve Gilde Healthcare IV U.A. | 10% Owner | 19 | $0 | $169.82M | 2021-03-15 |
| Gilde Healthcare Holding B.V. | 10% Owner | 37 | $0 | $107.16M | 2020-12-24 |
| Gilde Healthcare IV Management B.V. | 10% Owner | 13 | $6.50M | $29.96M | 2020-12-01 |
| Lewis Richard W. | 10% Owner | 12 | $0 | $1.33M | 2020-11-18 |
| Versant Ventures IV, LLC | 10% Owner | 4 | $0 | $0 | 2020-11-17 |
| Pardo Geoffrey B | Director | 1 | $0 | $0 | 2020-05-27 |
| Versant Venture Capital IV, L.P. | 10% Owner | 4 | $0 | $0 | 2020-05-27 |
| US VENTURE PARTNERS X LP | 10% Owner | 13 | $1.86M | $0 | 2020-05-27 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Hykes Andrew | President and CEO | D To issuer deriv | 2025-02-19 | 2025-02-19 | 44,693 | — | $0 | 0 | SEC↗ |
| Hykes Andrew | President and CEO | D To issuer deriv | 2025-02-19 | 2025-02-19 | 36,085 | — | $0 | 0 | SEC↗ |
| Lucchese Cynthia L | Director | D To issuer deriv | 2025-02-19 | 2025-02-19 | 49,719 | — | $0 | 0 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | D To issuer deriv | 2025-02-19 | 2025-02-19 | 11,761 | — | $0 | 0 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | D To issuer deriv | 2025-02-19 | 2025-02-19 | 5,293 | — | $0 | 0 | SEC↗ |
| Szyman Catherine M. | Director | D To issuer deriv | 2025-02-19 | 2025-02-19 | 49,719 | — | $0 | 0 | SEC↗ |
| Tu Thomas | Chief Medical Officer | D To issuer deriv | 2025-02-19 | 2025-02-19 | 16,599 | — | $0 | 0 | SEC↗ |
| Tu Thomas | Chief Medical Officer | D To issuer deriv | 2025-02-19 | 2025-02-19 | 16,231 | — | $0 | 0 | SEC↗ |
| Chambers Rebecca | Director | U Tender | 2025-02-19 | 2025-02-19 | 9,684 | — | $0 | 0 | SEC↗ |
| Hoffman William | Director | U Tender | 2025-02-19 | 2025-02-19 | 238,987 | — | $0 | 0 | SEC↗ |
| Hykes Andrew | President and CEO | U Tender | 2025-02-19 | 2025-02-19 | 717,637 | — | $0 | 0 | SEC↗ |
| Hykes Andrew | President and CEO | A Award | 2025-02-19 | 2025-02-19 | 20,393 | — | $0 | 717,637 | SEC↗ |
| Hykes Andrew | President and CEO | U Tender | 2025-02-19 | 2025-02-19 | 1,550 | — | $0 | 0 | SEC↗ |
| Hykes Andrew | President and CEO | U Tender | 2025-02-19 | 2025-02-19 | 1,550 | — | $0 | 0 | SEC↗ |
| Hykes Andrew | President and CEO | U Tender | 2025-02-19 | 2025-02-19 | 1,550 | — | $0 | 0 | SEC↗ |
| Hykes Andrew | President and CEO | U Tender | 2025-02-19 | 2025-02-19 | 1,000 | — | $0 | 0 | SEC↗ |
| Lucchese Cynthia L | Director | U Tender | 2025-02-19 | 2025-02-19 | 38,429 | — | $0 | 0 | SEC↗ |
| Mead Dana G Jr. | Director | U Tender | 2025-02-19 | 2025-02-19 | 11,148 | — | $0 | 0 | SEC↗ |
| MILDER DONALD B | Director | U Tender | 2025-02-19 | 2025-02-19 | 2,831,714 | — | $0 | 0 | SEC↗ |
| MILDER DONALD B | Director | U Tender | 2025-02-19 | 2025-02-19 | 259,126 | — | $0 | 0 | SEC↗ |
| ROOT JONATHAN D | Director | U Tender | 2025-02-19 | 2025-02-19 | 541,149 | — | $0 | 0 | SEC↗ |
| ROOT JONATHAN D | Director | U Tender | 2025-02-19 | 2025-02-19 | 335 | — | $0 | 0 | SEC↗ |
| Silva Karen | Principal Accounting Officer | U Tender | 2025-02-19 | 2025-02-19 | 14,719 | — | $0 | 0 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | U Tender | 2025-02-19 | 2025-02-19 | 67,502 | — | $0 | 0 | SEC↗ |
| Szyman Catherine M. | Director | U Tender | 2025-02-19 | 2025-02-19 | 22,429 | — | $0 | 0 | SEC↗ |
| Tu Thomas | Chief Medical Officer | U Tender | 2025-02-19 | 2025-02-19 | 478,767 | — | $0 | 0 | SEC↗ |
| Tu Thomas | Chief Medical Officer | A Award | 2025-02-19 | 2025-02-19 | 7,406 | — | $0 | 478,767 | SEC↗ |
| Warner Robert Keith | Director | U Tender | 2025-02-19 | 2025-02-19 | 12,149 | — | $0 | 0 | SEC↗ |
| Tu Thomas | Chief Medical Officer | M Exercise deriv | 2025-02-10 | 2025-02-12 | 139,584 | — | $0 | 0 | SEC↗ |
| Tu Thomas | Chief Medical Officer | M Exercise deriv | 2025-02-10 | 2025-02-12 | 8,420 | — | $0 | 0 | SEC↗ |
| Hykes Andrew | President and CEO | M Exercise deriv | 2025-02-10 | 2025-02-12 | 16,719 | — | $0 | 0 | SEC↗ |
| Hykes Andrew | President and CEO | M Exercise deriv | 2025-02-10 | 2025-02-12 | 161,100 | — | $0 | 0 | SEC↗ |
| Hykes Andrew | President and CEO | M Exercise deriv | 2025-02-10 | 2025-02-12 | 16,719 | — | $0 | 0 | SEC↗ |
| Tu Thomas | Chief Medical Officer | M Exercise | 2025-02-10 | 2025-02-12 | 8,420 | $6.45 | $54.3K | 471,361 | SEC↗ |
| Tu Thomas | Chief Medical Officer | M Exercise | 2025-02-10 | 2025-02-12 | 139,584 | $0.46 | $64.2K | 462,941 | SEC↗ |
| Hykes Andrew | President and CEO | M Exercise | 2025-02-10 | 2025-02-12 | 161,100 | $0.43 | $69.3K | 663,806 | SEC↗ |
| Hykes Andrew | President and CEO | M Exercise | 2025-02-10 | 2025-02-12 | 16,719 | $6.45 | $107.8K | 680,525 | SEC↗ |
| Hykes Andrew | President and CEO | M Exercise | 2025-02-10 | 2025-02-12 | 16,719 | $0.46 | $7.7K | 697,244 | SEC↗ |
| Silva Karen | Principal Accounting Officer | A Award | 2025-02-04 | 2025-02-06 | 5,504 | — | $0 | 14,719 | SEC↗ |
| Tu Thomas | Chief Medical Officer | A Award | 2025-02-04 | 2025-02-06 | 21,102 | — | $0 | 323,357 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | A Award | 2025-02-04 | 2025-02-06 | 21,102 | — | $0 | 67,502 | SEC↗ |
| Hykes Andrew | President and CEO | A Award | 2025-02-04 | 2025-02-06 | 67,282 | — | $0 | 502,706 | SEC↗ |
| Hoffman William | Director | S Sale | 2025-01-06 | 2025-01-08 | 141,075 | $60.13 | $8.48M | 297,912 | SEC↗ |
| Hoffman William | Director | S Sale | 2025-01-06 | 2025-01-08 | 58,925 | $61.27 | $3.61M | 238,987 | SEC↗ |
| Hoffman William | Director | F Tax w/h | 2025-01-01 | 2025-01-03 | 1,533 | $51.05 | $78.3K | 438,987 | SEC↗ |
| Hoffman William | Director | F Tax w/h | 2025-01-01 | 2025-01-03 | 713 | $51.05 | $36.4K | 440,520 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2025-01-01 | 2025-01-03 | 516 | $51.05 | $26.3K | 301,733 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2025-01-01 | 2025-01-03 | 751 | $51.05 | $38.3K | 302,249 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2025-01-01 | 2025-01-03 | 699 | $51.05 | $35.7K | 303,000 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2025-01-01 | 2025-01-03 | 337 | $51.05 | $17.2K | 303,699 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | F Tax w/h | 2025-01-01 | 2025-01-03 | 63 | $51.05 | $3.2K | 47,292 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | F Tax w/h | 2025-01-01 | 2025-01-03 | 149 | $51.05 | $7.6K | 47,143 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | F Tax w/h | 2025-01-01 | 2025-01-03 | 176 | $51.05 | $9.0K | 46,967 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | F Tax w/h | 2025-01-01 | 2025-01-03 | 227 | $51.05 | $11.6K | 46,740 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | F Tax w/h | 2025-01-01 | 2025-01-03 | 146 | $51.05 | $7.5K | 46,318 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | F Tax w/h | 2025-01-01 | 2025-01-03 | 276 | $51.05 | $14.1K | 46,464 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2025-01-01 | 2025-01-03 | 1,319 | $51.05 | $67.3K | 434,901 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2025-01-01 | 2025-01-03 | 1,632 | $51.05 | $83.3K | 436,220 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2025-01-01 | 2025-01-03 | 949 | $51.05 | $48.4K | 437,852 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2025-01-01 | 2025-01-03 | 509 | $51.05 | $26.0K | 438,801 | SEC↗ |
| Hykes Andrew | President and CEO | S Sale | 2024-12-20 | 2024-12-20 | 2,400 | $55.20 | $132.5K | 439,910 | SEC↗ |
| Hykes Andrew | President and CEO | S Sale | 2024-12-20 | 2024-12-20 | 600 | $55.65 | $33.4K | 439,310 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-12-16 | 2024-12-18 | 2,347 | $56.82 | $133.4K | 461,233 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-12-16 | 2024-12-18 | 7,467 | $56.51 | $422.0K | 441,365 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-12-16 | 2024-12-18 | 10,301 | $55.27 | $569.3K | 448,832 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-12-16 | 2024-12-18 | 2,100 | $54.42 | $114.3K | 459,133 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-12-16 | 2024-12-18 | 132 | $56.89 | $7.5K | 441,233 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-12-16 | 2024-12-18 | 13,560 | $56.45 | $765.5K | 463,580 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-12-16 | 2024-12-18 | 20,917 | $55.23 | $1.16M | 477,140 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-12-16 | 2024-12-18 | 3,176 | $54.33 | $172.6K | 498,057 | SEC↗ |
| Tu Thomas | Chief Medical Officer | S Sale | 2024-12-10 | 2024-12-12 | 4,000 | $55.00 | $220.0K | 304,036 | SEC↗ |
| Silva Karen | Principal Accounting Officer | A Award | 2024-12-01 | 2024-12-03 | 9,215 | — | $0 | 9,215 | SEC↗ |
| Hykes Andrew | President and CEO | S Sale | 2024-11-20 | 2024-11-22 | 3,000 | $50.83 | $152.5K | 442,310 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-11-18 | 2024-11-20 | 3,216 | $52.11 | $167.6K | 521,233 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-11-18 | 2024-11-20 | 10,250 | $50.64 | $519.1K | 510,983 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-11-18 | 2024-11-20 | 9,750 | $51.16 | $498.8K | 501,233 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-11-18 | 2024-11-20 | 33,784 | $51.32 | $1.73M | 524,449 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-11-18 | 2024-11-20 | 3,000 | $50.09 | $150.3K | 558,233 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-10-29 | 2024-10-31 | 20,000 | $50.00 | $1.00M | 561,233 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-10-29 | 2024-10-31 | 20,000 | $50.10 | $1.00M | 581,233 | SEC↗ |
| Hykes Andrew | President and CEO | S Sale | 2024-10-29 | 2024-10-31 | 3,000 | $50.00 | $150.0K | 445,310 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-10-16 | 2024-10-18 | 27,804 | $44.78 | $1.25M | 613,429 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-10-16 | 2024-10-18 | 12,196 | $45.57 | $555.8K | 601,233 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-10-01 | 2024-10-02 | 662 | $40.63 | $26.9K | 177,991 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-10-01 | 2024-10-02 | 331 | $40.63 | $13.4K | 179,269 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-10-01 | 2024-10-02 | 458 | $40.63 | $18.6K | 177,533 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-10-01 | 2024-10-02 | 616 | $40.63 | $25.0K | 178,653 | SEC↗ |
| Hoffman William | Director | F Tax w/h | 2024-10-01 | 2024-10-03 | 1,385 | $40.63 | $56.3K | 641,233 | SEC↗ |
| Hoffman William | Director | F Tax w/h | 2024-10-01 | 2024-10-03 | 678 | $40.63 | $27.5K | 642,618 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-10-01 | 2024-10-03 | 1,475 | $40.63 | $59.9K | 449,602 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-10-01 | 2024-10-03 | 947 | $40.63 | $38.5K | 451,077 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-10-01 | 2024-10-03 | 508 | $40.63 | $20.6K | 452,024 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-10-01 | 2024-10-03 | 1,292 | $40.63 | $52.5K | 448,310 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-10-01 | 2024-10-03 | 632 | $40.63 | $25.7K | 309,185 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-10-01 | 2024-10-03 | 679 | $40.63 | $27.6K | 308,506 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-10-01 | 2024-10-03 | 470 | $40.63 | $19.1K | 308,036 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-10-01 | 2024-10-03 | 339 | $40.63 | $13.8K | 309,817 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | F Tax w/h | 2024-10-01 | 2024-10-03 | 268 | $40.63 | $10.9K | 48,128 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | A Award | 2024-10-01 | 2024-10-03 | 5,695 | — | $0 | 48,396 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | F Tax w/h | 2024-10-01 | 2024-10-03 | 129 | $40.63 | $5.2K | 47,945 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | F Tax w/h | 2024-10-01 | 2024-10-03 | 152 | $40.63 | $6.2K | 47,793 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | F Tax w/h | 2024-10-01 | 2024-10-03 | 198 | $40.63 | $8.0K | 47,595 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | F Tax w/h | 2024-10-01 | 2024-10-03 | 240 | $40.63 | $9.8K | 47,355 | SEC↗ |
| Strange Kevin T | Chief Financial Officer | F Tax w/h | 2024-10-01 | 2024-10-03 | 54 | $40.63 | $2.2K | 48,074 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-09-16 | 2024-09-18 | 32,614 | $45.73 | $1.49M | 650,682 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-09-16 | 2024-09-18 | 7,386 | $46.27 | $341.8K | 643,296 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise deriv | 2024-09-12 | 2024-09-13 | 3,000 | — | $0 | 58,477 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-09-12 | 2024-09-13 | 1,609 | $44.38 | $71.4K | 180,991 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-09-12 | 2024-09-13 | 500 | $46.34 | $23.2K | 179,600 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise | 2024-09-12 | 2024-09-13 | 3,000 | $0.46 | $1.4K | 182,600 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-09-12 | 2024-09-13 | 891 | $45.80 | $40.8K | 180,100 | SEC↗ |
| Hykes Andrew | President and CEO | S Sale | 2024-08-20 | 2024-08-22 | 3,000 | $50.00 | $150.0K | 452,532 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-08-19 | 2024-08-20 | 20,000 | $50.30 | $1.01M | 683,296 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-08-16 | 2024-08-20 | 24,553 | $48.72 | $1.20M | 718,743 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-08-16 | 2024-08-20 | 15,447 | $49.17 | $759.5K | 703,296 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise deriv | 2024-08-12 | 2024-08-14 | 5,000 | — | $0 | 61,477 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise | 2024-08-12 | 2024-08-14 | 5,000 | $0.46 | $2.3K | 184,600 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-08-12 | 2024-08-14 | 4,574 | $47.94 | $219.3K | 180,026 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-08-12 | 2024-08-14 | 426 | $48.56 | $20.7K | 179,600 | SEC↗ |
| Hykes Andrew | President and CEO | S Sale | 2024-07-22 | 2024-07-24 | 3,000 | $55.23 | $165.7K | 455,252 | SEC↗ |
| Tu Thomas | Chief Medical Officer | S Sale | 2024-07-16 | 2024-07-18 | 3,480 | $55.16 | $192.0K | 309,777 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-07-16 | 2024-07-18 | 15,974 | $57.90 | $924.9K | 765,908 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-07-16 | 2024-07-18 | 4,507 | $57.72 | $260.1K | 746,539 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-07-16 | 2024-07-18 | 3,243 | $58.17 | $188.6K | 743,296 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-07-16 | 2024-07-18 | 4,798 | $56.53 | $271.2K | 751,046 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-07-16 | 2024-07-18 | 5,652 | $55.53 | $313.9K | 755,844 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-07-16 | 2024-07-18 | 1,800 | $54.70 | $98.5K | 761,496 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-07-16 | 2024-07-18 | 2,612 | $58.25 | $152.1K | 763,296 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-07-16 | 2024-07-18 | 8,351 | $56.58 | $472.5K | 781,882 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-07-16 | 2024-07-18 | 9,659 | $55.53 | $536.4K | 790,233 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-07-16 | 2024-07-18 | 3,404 | $54.76 | $186.4K | 799,892 | SEC↗ |
| Tu Thomas | Chief Medical Officer | S Sale | 2024-07-15 | 2024-07-16 | 3,300 | $55.08 | $181.8K | 316,557 | SEC↗ |
| Tu Thomas | Chief Medical Officer | S Sale | 2024-07-15 | 2024-07-16 | 9,920 | $55.09 | $546.5K | 319,857 | SEC↗ |
| Tu Thomas | Chief Medical Officer | S Sale | 2024-07-15 | 2024-07-16 | 3,300 | $55.10 | $181.8K | 313,257 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise deriv | 2024-07-12 | 2024-07-16 | 5,000 | — | $0 | 66,477 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-07-12 | 2024-07-16 | 1,965 | $54.31 | $106.7K | 179,227 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-07-12 | 2024-07-16 | 3,035 | $53.72 | $163.0K | 181,192 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise | 2024-07-12 | 2024-07-16 | 5,000 | $0.46 | $2.3K | 184,227 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-07-01 | 2024-07-03 | 679 | $50.19 | $34.1K | 330,247 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-07-01 | 2024-07-03 | 339 | $50.19 | $17.0K | 331,558 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-07-01 | 2024-07-03 | 470 | $50.19 | $23.6K | 329,777 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-07-01 | 2024-07-03 | 632 | $50.19 | $31.7K | 330,926 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-07-01 | 2024-07-03 | 616 | $50.19 | $30.9K | 180,347 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-07-01 | 2024-07-03 | 662 | $50.19 | $33.2K | 179,685 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-07-01 | 2024-07-03 | 458 | $50.19 | $23.0K | 179,227 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-07-01 | 2024-07-03 | 331 | $50.19 | $16.6K | 180,963 | SEC↗ |
| Hykes Andrew | President and CEO | S Sale | 2024-07-01 | 2024-07-03 | 3,000 | $50.08 | $150.2K | 462,474 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-07-01 | 2024-07-03 | 508 | $50.19 | $25.5K | 461,966 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-07-01 | 2024-07-03 | 947 | $50.19 | $47.5K | 461,019 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-07-01 | 2024-07-03 | 1,475 | $50.19 | $74.0K | 459,544 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-07-01 | 2024-07-03 | 1,292 | $50.19 | $64.8K | 458,252 | SEC↗ |
| Hoffman William | Director | F Tax w/h | 2024-07-01 | 2024-07-03 | 1,385 | $50.19 | $69.5K | 803,296 | SEC↗ |
| Hoffman William | Director | F Tax w/h | 2024-07-01 | 2024-07-03 | 678 | $50.19 | $34.0K | 804,681 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-07-01 | 2024-07-03 | 20,000 | $50.15 | $1.00M | 805,359 | SEC↗ |
| Chambers Rebecca | Director | S Sale | 2024-06-21 | 2024-06-24 | 260 | $45.99 | $12.0K | 9,684 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-06-17 | 2024-06-20 | 100 | $45.85 | $4.6K | 825,359 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-06-17 | 2024-06-20 | 31,600 | $43.31 | $1.37M | 833,759 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-06-17 | 2024-06-20 | 6,175 | $44.16 | $272.7K | 827,584 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-06-17 | 2024-06-20 | 2,125 | $45.04 | $95.7K | 825,459 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise deriv | 2024-06-12 | 2024-06-14 | 5,000 | — | $0 | 71,477 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise | 2024-06-12 | 2024-06-14 | 5,000 | $0.46 | $2.3K | 186,294 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-06-12 | 2024-06-14 | 2,502 | $48.04 | $120.2K | 181,294 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-06-12 | 2024-06-14 | 2,498 | $47.15 | $117.8K | 183,796 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-05-28 | 2024-05-30 | 60,000 | $50.13 | $3.01M | 865,359 | SEC↗ |
| Hykes Andrew | President and CEO | S Sale | 2024-05-28 | 2024-05-30 | 3,000 | $50.00 | $150.0K | 465,474 | SEC↗ |
| Chambers Rebecca | Director | S Sale | 2024-05-20 | 2024-05-21 | 964 | $45.39 | $43.8K | 9,944 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-05-16 | 2024-05-17 | 7,299 | $47.00 | $343.1K | 925,359 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-05-16 | 2024-05-17 | 32,701 | $46.51 | $1.52M | 932,658 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise deriv | 2024-05-13 | 2024-05-15 | 6,000 | — | $0 | 76,477 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-05-13 | 2024-05-15 | 300 | $44.49 | $13.3K | 186,994 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise | 2024-05-13 | 2024-05-15 | 6,000 | $0.46 | $2.8K | 187,294 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-05-13 | 2024-05-15 | 2,200 | $46.55 | $102.4K | 181,294 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-05-13 | 2024-05-15 | 3,500 | $45.73 | $160.1K | 183,494 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-05-01 | 2024-05-03 | 200 | $43.61 | $8.7K | 965,359 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-05-01 | 2024-05-03 | 2,491 | $42.73 | $106.4K | 965,559 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-05-01 | 2024-05-03 | 35,858 | $41.94 | $1.50M | 968,050 | SEC↗ |
| Chambers Rebecca | Director | A Award | 2024-04-24 | 2024-04-26 | 4,126 | $42.41 | $175.0K | 10,908 | SEC↗ |
| Hoffman William | Director | A Award | 2024-04-24 | 2024-04-26 | 4,126 | $42.41 | $175.0K | 1,003,908 | SEC↗ |
| Lucchese Cynthia L | Director | A Award | 2024-04-24 | 2024-04-26 | 4,126 | $42.41 | $175.0K | 38,429 | SEC↗ |
| Mead Dana G Jr. | Director | A Award | 2024-04-24 | 2024-04-26 | 4,126 | $42.41 | $175.0K | 11,148 | SEC↗ |
| MILDER DONALD B | Director | A Award | 2024-04-24 | 2024-04-26 | 4,126 | $42.41 | $175.0K | 259,126 | SEC↗ |
| ROOT JONATHAN D | Director | A Award | 2024-04-24 | 2024-04-26 | 4,126 | $42.41 | $175.0K | 541,149 | SEC↗ |
| Szyman Catherine M. | Director | A Award | 2024-04-24 | 2024-04-26 | 4,126 | $42.41 | $175.0K | 22,429 | SEC↗ |
| Warner Robert Keith | Director | A Award | 2024-04-24 | 2024-04-26 | 4,126 | $42.41 | $175.0K | 12,149 | SEC↗ |
| Lucchese Cynthia L | Director | A Award | 2024-04-24 | 2024-05-31 | 4,126 | $42.41 | $175.0K | 38,429 | SEC↗ |
| Mead Dana G Jr. | Director | A Award | 2024-04-24 | 2024-05-31 | 4,126 | $42.41 | $175.0K | 11,148 | SEC↗ |
| ROOT JONATHAN D | Director | A Award | 2024-04-24 | 2024-05-31 | 4,126 | $42.41 | $175.0K | 541,149 | SEC↗ |
| Szyman Catherine M. | Director | A Award | 2024-04-24 | 2024-05-31 | 4,126 | $42.41 | $175.0K | 22,429 | SEC↗ |
| Warner Robert Keith | Director | A Award | 2024-04-24 | 2024-05-31 | 4,126 | $42.41 | $175.0K | 12,149 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-04-16 | 2024-04-18 | 1,451 | $40.00 | $58.0K | 999,782 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise deriv | 2024-04-12 | 2024-04-16 | 6,000 | — | $0 | 82,477 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise | 2024-04-12 | 2024-04-16 | 6,000 | $0.46 | $2.8K | 187,294 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-04-12 | 2024-04-16 | 6,000 | $40.96 | $245.8K | 181,294 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-04-01 | 2024-04-03 | 469 | — | $0 | 331,897 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-04-01 | 2024-04-03 | 679 | — | $0 | 332,366 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-04-01 | 2024-04-03 | 632 | — | $0 | 333,045 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-04-01 | 2024-04-03 | 339 | — | $0 | 333,677 | SEC↗ |
| Hoffman William | Director | F Tax w/h | 2024-04-01 | 2024-04-03 | 678 | — | $0 | 1,002,618 | SEC↗ |
| Hoffman William | Director | F Tax w/h | 2024-04-01 | 2024-04-03 | 1,385 | — | $0 | 1,001,233 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-04-01 | 2024-04-03 | 331 | — | $0 | 183,030 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-04-01 | 2024-04-03 | 616 | — | $0 | 182,414 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-04-01 | 2024-04-03 | 458 | — | $0 | 181,294 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-04-01 | 2024-04-03 | 662 | — | $0 | 181,752 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-04-01 | 2024-04-03 | 508 | — | $0 | 472,188 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-04-01 | 2024-04-03 | 947 | — | $0 | 471,241 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-04-01 | 2024-04-03 | 1,292 | — | $0 | 468,474 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-04-01 | 2024-04-03 | 1,475 | — | $0 | 469,766 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-03-18 | 2024-03-20 | 12,508 | $41.45 | $518.5K | 1,003,296 | SEC↗ |
| Hoffman William | Director | S Sale | 2024-03-18 | 2024-03-20 | 27,492 | $40.98 | $1.13M | 1,015,804 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise deriv | 2024-03-12 | 2024-03-14 | 6,000 | — | $0 | 88,477 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-03-12 | 2024-03-14 | 5,999 | $41.91 | $251.4K | 183,362 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise | 2024-03-12 | 2024-03-14 | 6,000 | $0.46 | $2.8K | 189,361 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2024-03-12 | 2024-03-14 | 1 | $42.58 | $43 | 183,361 | SEC↗ |
| Hykes Andrew | President and CEO | A Award deriv | 2024-02-16 | 2024-02-21 | 44,693 | $58.44 | $2.61M | 44,693 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | A Award deriv | 2024-02-16 | 2024-02-21 | 16,231 | $58.44 | $948.5K | 16,231 | SEC↗ |
| Tu Thomas | Chief Medical Officer | A Award deriv | 2024-02-16 | 2024-02-21 | 16,231 | $58.44 | $948.5K | 16,231 | SEC↗ |
| Hykes Andrew | President and CEO | A Award | 2024-02-16 | 2024-02-21 | 40,786 | — | $0 | 472,696 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | A Award | 2024-02-16 | 2024-02-21 | 14,812 | — | $0 | 183,361 | SEC↗ |
| Tu Thomas | Chief Medical Officer | A Award | 2024-02-16 | 2024-02-21 | 14,812 | — | $0 | 334,016 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-01-01 | 2024-01-03 | 750 | $64.92 | $48.7K | 319,149 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-01-01 | 2024-01-03 | 698 | $64.92 | $45.3K | 319,899 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2024-01-01 | 2024-01-03 | 335 | $64.92 | $21.7K | 320,597 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-01-01 | 2024-01-03 | 682 | $64.92 | $44.3K | 169,221 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-01-01 | 2024-01-03 | 327 | $64.92 | $21.2K | 169,903 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2024-01-01 | 2024-01-03 | 733 | $64.92 | $47.6K | 168,488 | SEC↗ |
| Hoffman William | Director | F Tax w/h | 2024-01-01 | 2024-01-03 | 675 | $64.92 | $43.8K | 1,044,818 | SEC↗ |
| Hoffman William | Director | F Tax w/h | 2024-01-01 | 2024-01-03 | 1,522 | $64.92 | $98.8K | 1,043,296 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-01-01 | 2024-01-03 | 945 | $64.92 | $61.3K | 433,364 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-01-01 | 2024-01-03 | 508 | $64.92 | $33.0K | 434,309 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2024-01-01 | 2024-01-03 | 1,610 | $64.92 | $104.5K | 431,754 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-12-15 | 2023-12-19 | 1,700 | $65.41 | $111.2K | 1,045,493 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-12-15 | 2023-12-19 | 8,300 | $65.01 | $539.6K | 1,047,193 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-12-15 | 2023-12-19 | 11,018 | $64.98 | $715.9K | 1,059,475 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-12-15 | 2023-12-19 | 3,982 | $65.38 | $260.3K | 1,055,493 | SEC↗ |
| MILDER DONALD B | Director | G Gift | 2023-12-14 | 2023-12-15 | 100,000 | — | $0 | 2,931,714 | SEC↗ |
| MILDER DONALD B | Director | G Gift | 2023-12-14 | 2023-12-15 | 100,000 | — | $0 | 2,831,714 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise deriv | 2023-12-12 | 2023-12-14 | 6,500 | — | $0 | 94,477 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2023-12-12 | 2023-12-14 | 3,582 | $63.16 | $226.2K | 170,230 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2023-12-12 | 2023-12-14 | 2,918 | $62.24 | $181.6K | 173,812 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise | 2023-12-12 | 2023-12-14 | 6,500 | $0.46 | $3.0K | 176,730 | SEC↗ |
| Hoffman William | Director | M Exercise deriv | 2023-12-04 | 2023-12-06 | 38,324 | — | $0 | 0 | SEC↗ |
| Hoffman William | Director | M Exercise deriv | 2023-12-04 | 2023-12-06 | 65,168 | — | $0 | 0 | SEC↗ |
| Hoffman William | Director | M Exercise | 2023-12-04 | 2023-12-06 | 38,324 | $0.43 | $16.5K | 1,070,493 | SEC↗ |
| Hoffman William | Director | M Exercise | 2023-12-04 | 2023-12-06 | 65,168 | $0.43 | $28.0K | 1,032,169 | SEC↗ |
| Hykes Andrew | President and CEO | S Sale | 2023-11-16 | 2023-11-17 | 16,415 | $60.20 | $988.2K | 434,817 | SEC↗ |
| Hykes Andrew | President and CEO | S Sale | 2023-11-16 | 2023-11-17 | 21,033 | $59.53 | $1.25M | 451,232 | SEC↗ |
| Tu Thomas | Chief Medical Officer | S Sale | 2023-11-16 | 2023-11-17 | 14,295 | $59.53 | $851.0K | 332,088 | SEC↗ |
| Tu Thomas | Chief Medical Officer | S Sale | 2023-11-16 | 2023-11-17 | 11,156 | $60.20 | $671.6K | 320,932 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-11-15 | 2023-11-17 | 4,295 | $61.05 | $262.2K | 986,334 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-11-15 | 2023-11-17 | 1,372 | $59.72 | $81.9K | 990,629 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-11-15 | 2023-11-17 | 2,369 | $60.98 | $144.5K | 973,732 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-11-15 | 2023-11-17 | 9,333 | $61.57 | $574.6K | 977,001 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-11-15 | 2023-11-17 | 6,731 | $61.54 | $414.2K | 967,001 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-11-15 | 2023-11-17 | 900 | $59.62 | $53.7K | 976,101 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise deriv | 2023-11-13 | 2023-11-15 | 6,500 | — | $0 | 100,977 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2023-11-13 | 2023-11-15 | 400 | $56.93 | $22.8K | 170,230 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2023-11-13 | 2023-11-15 | 4,500 | $56.18 | $252.8K | 170,630 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise | 2023-11-13 | 2023-11-15 | 6,500 | $0.46 | $3.0K | 176,730 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2023-11-13 | 2023-11-15 | 1,600 | $55.49 | $88.8K | 175,130 | SEC↗ |
| MILDER DONALD B | Director | P Buy | 2023-11-08 | 2024-05-31 | 2,000 | $53.54 | $107.1K | 3,031,614 | SEC↗ |
| MILDER DONALD B | Director | P Buy | 2023-11-08 | 2024-05-31 | 100 | $52.23 | $5.2K | 3,031,714 | SEC↗ |
| MILDER DONALD B | Director | P Buy | 2023-11-08 | 2023-11-08 | 2,000 | $53.54 | $107.1K | 3,031,614 | SEC↗ |
| MILDER DONALD B | Director | P Buy | 2023-11-08 | 2023-11-08 | 100 | $52.23 | $5.2K | 3,031,714 | SEC↗ |
| MILDER DONALD B | Director | P Buy | 2023-11-07 | 2024-05-31 | 54,000 | $53.44 | $2.89M | 3,029,614 | SEC↗ |
| MILDER DONALD B | Director | P Buy | 2023-11-07 | 2023-11-08 | 54,000 | $53.44 | $2.89M | 3,029,614 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-10-16 | 2023-10-18 | 3,732 | $56.79 | $211.9K | 1,011,569 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-10-16 | 2023-10-18 | 400 | $54.57 | $21.8K | 1,001,601 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-10-16 | 2023-10-18 | 9,568 | $57.80 | $553.0K | 1,002,001 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-10-16 | 2023-10-18 | 1,200 | $55.88 | $67.1K | 1,015,301 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-10-16 | 2023-10-18 | 1,085 | $56.09 | $60.9K | 1,000,516 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-10-16 | 2023-10-18 | 2,686 | $56.96 | $153.0K | 997,830 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-10-16 | 2023-10-18 | 5,829 | $57.83 | $337.1K | 992,001 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-10-16 | 2023-10-18 | 500 | $54.60 | $27.3K | 1,016,501 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise deriv | 2023-10-12 | 2023-10-16 | 6,500 | — | $0 | 107,477 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2023-10-12 | 2023-10-16 | 900 | $56.86 | $51.2K | 170,730 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2023-10-12 | 2023-10-16 | 2,490 | $55.64 | $138.5K | 171,630 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2023-10-12 | 2023-10-16 | 2,610 | $55.07 | $143.7K | 174,120 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise | 2023-10-12 | 2023-10-16 | 6,500 | $0.46 | $3.0K | 176,730 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2023-10-12 | 2023-10-16 | 500 | $57.78 | $28.9K | 170,230 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2023-10-01 | 2023-10-03 | 602 | $65.40 | $39.4K | 170,877 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2023-10-01 | 2023-10-03 | 647 | $65.40 | $42.3K | 170,230 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | F Tax w/h | 2023-10-01 | 2023-10-03 | 323 | $65.40 | $21.1K | 171,479 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2023-10-01 | 2023-10-03 | 618 | $65.40 | $40.4K | 347,047 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2023-10-01 | 2023-10-03 | 664 | $65.40 | $43.4K | 346,383 | SEC↗ |
| Tu Thomas | Chief Medical Officer | F Tax w/h | 2023-10-01 | 2023-10-03 | 332 | $65.40 | $21.7K | 347,665 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2023-10-01 | 2023-10-03 | 927 | $65.40 | $60.6K | 473,708 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2023-10-01 | 2023-10-03 | 1,443 | $65.40 | $94.4K | 472,265 | SEC↗ |
| Hykes Andrew | President and CEO | F Tax w/h | 2023-10-01 | 2023-10-03 | 497 | $65.40 | $32.5K | 474,635 | SEC↗ |
| Hoffman William | Director | F Tax w/h | 2023-10-01 | 2023-10-03 | 663 | $65.40 | $43.4K | 1,018,356 | SEC↗ |
| Hoffman William | Director | F Tax w/h | 2023-10-01 | 2023-10-03 | 1,355 | $65.40 | $88.6K | 1,017,001 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-09-15 | 2023-09-19 | 3,229 | $66.27 | $214.0K | 1,029,826 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-09-15 | 2023-09-19 | 7,099 | $66.40 | $471.4K | 1,040,956 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-09-15 | 2023-09-19 | 7,901 | $67.05 | $529.8K | 1,033,055 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-09-15 | 2023-09-19 | 100 | $67.58 | $6.8K | 1,023,055 | SEC↗ |
| Hoffman William | Director | S Sale | 2023-09-15 | 2023-09-19 | 6,671 | $66.95 | $446.6K | 1,023,155 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise deriv | 2023-09-12 | 2023-09-14 | 6,500 | — | $0 | 113,977 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2023-09-12 | 2023-09-14 | 1,055 | $66.59 | $70.3K | 177,247 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2023-09-12 | 2023-09-14 | 2,120 | $67.70 | $143.5K | 175,127 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | M Exercise | 2023-09-12 | 2023-09-14 | 6,500 | $0.46 | $3.0K | 178,302 | SEC↗ |
| Hill, Mitch C. | Chief Financial Officer | S Sale | 2023-09-12 | 2023-09-14 | 3,325 | $68.35 | $227.3K | 171,802 | SEC↗ |