Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$0
Insiders on file
26
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| HASTINGS PAUL J | See Remarks | 35 | $0 | $1.59M | 2026-06-18 |
| Vratsanos George | Director | 3 | $0 | $0 | 2026-06-10 |
| Scheiner Zachary | Director | 7 | $0 | $0 | 2026-06-10 |
| Thedinga Angela | Director | 6 | $0 | $0 | 2026-06-10 |
| Shah Rajeev M. | Director, 10% Owner | 7 | $93.00M | $0 | 2026-06-10 |
| Behbahani Ali | Director | 3 | $0 | $0 | 2026-06-10 |
| Dybbs Michael | Director | 7 | $0 | $0 | 2026-06-10 |
| George Simeon | Director | 10 | $40.00M | $0 | 2026-06-10 |
| PATTERSON LEONE D | Director | 8 | $0 | $0 | 2026-06-10 |
| Mahmood Nadir | See Remarks | 47 | $0 | $1.04M | 2026-01-15 |
| Rose Shawn Marshall | See Remarks | 3 | $0 | $0 | 2026-01-06 |
| RA Capital Healthcare Fund LP | Director, 10% Owner | 3 | $0 | $0 | 2025-06-05 |
| Levin Alyssa | See Remarks | 6 | $0 | $12.8K | 2025-01-15 |
| Shook David | See Remarks | 16 | $0 | $58.1K | 2025-01-15 |
| Brandenberger Ralph | Sr. VP, Technical Operations | 73 | $0 | $935.0K | 2025-01-15 |
| Hager Alicia J. | Chief Legal Officer | 19 | $0 | $101.6K | 2025-01-15 |
| Trager James | Chief Scientific Officer | 33 | $0 | $666.7K | 2024-06-18 |
| RA CAPITAL MANAGEMENT, L.P. | Director, 10% Owner | 3 | $60.00M | $0 | 2024-06-13 |
| Azzam Fouad Oscar | Director | 4 | $0 | $0 | 2023-06-07 |
| Aynechi Tiba | Director | 1 | $0 | $0 | 2022-06-08 |
| Shawver Laura | Director | 4 | $0 | $0 | 2022-06-08 |
| Rajangam Kanya | Chief Medical Officer | 7 | $0 | $372.8K | 2022-01-14 |
| Deerfield Mgmt IV, L.P. | 10% Owner | 6 | $18.00M | $0 | 2020-07-14 |
| Novo Holdings A/S | 10% Owner | 4 | $10.00M | $0 | 2020-07-14 |
| GLAXOSMITHKLINE PLC | Director, 10% Owner | 8 | $15.00M | $0 | 2020-07-14 |
| Plunkett Matthew | Chief Financial Officer | 1 | $0 | $0 | 2020-07-09 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2026-06-18 | 2026-06-22 | 1,776 | $2.71 | $4.8K | 390,247 | SEC↗ |
| Thedinga Angela | Director | A Award deriv | 2026-06-10 | 2026-06-11 | 37,000 | — | $0 | 37,000 | SEC↗ |
| Dybbs Michael | Director | A Award deriv | 2026-06-10 | 2026-06-11 | 37,000 | — | $0 | 37,000 | SEC↗ |
| PATTERSON LEONE D | Director | A Award deriv | 2026-06-10 | 2026-06-11 | 37,000 | — | $0 | 37,000 | SEC↗ |
| Scheiner Zachary | Director | A Award deriv | 2026-06-10 | 2026-06-11 | 37,000 | — | $0 | 37,000 | SEC↗ |
| Vratsanos George | Director | A Award deriv | 2026-06-10 | 2026-06-11 | 37,000 | — | $0 | 37,000 | SEC↗ |
| George Simeon | Director | A Award deriv | 2026-06-10 | 2026-06-11 | 37,000 | — | $0 | 37,000 | SEC↗ |
| Behbahani Ali | Director | A Award deriv | 2026-06-10 | 2026-06-11 | 37,000 | — | $0 | 37,000 | SEC↗ |
| Shah Rajeev M. | Director, 10% Owner | A Award deriv | 2026-06-10 | 2026-06-11 | 37,000 | — | $0 | 37,000 | SEC↗ |
| Mahmood Nadir | President | S Sale | 2026-01-15 | 2026-01-20 | 5,649 | $2.07 | $11.7K | 167,727 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2026-01-15 | 2026-01-20 | 26,046 | $2.07 | $53.9K | 390,023 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award deriv | 2026-01-06 | 2026-01-08 | 562,000 | — | $0 | 562,000 | SEC↗ |
| Mahmood Nadir | President | A Award deriv | 2026-01-06 | 2026-01-08 | 160,000 | — | $0 | 160,000 | SEC↗ |
| Rose Shawn Marshall | See Remarks | A Award deriv | 2026-01-06 | 2026-01-08 | 139,000 | — | $0 | 139,000 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award | 2026-01-06 | 2026-01-08 | 94,000 | — | $0 | 416,069 | SEC↗ |
| Mahmood Nadir | President | A Award | 2026-01-06 | 2026-01-08 | 80,000 | — | $0 | 173,376 | SEC↗ |
| Rose Shawn Marshall | See Remarks | A Award | 2026-01-06 | 2026-01-08 | 70,000 | — | $0 | 70,000 | SEC↗ |
| Rose Shawn Marshall | See Remarks | A Award deriv | 2025-06-23 | 2025-06-25 | 500,000 | — | $0 | 500,000 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2025-06-18 | 2025-06-20 | 1,790 | $1.79 | $3.2K | 320,069 | SEC↗ |
| Dybbs Michael | Director | A Award deriv | 2025-06-05 | 2025-06-09 | 46,000 | — | $0 | 46,000 | SEC↗ |
| PATTERSON LEONE D | Director | A Award deriv | 2025-06-05 | 2025-06-09 | 46,000 | — | $0 | 46,000 | SEC↗ |
| Scheiner Zachary | Director | A Award deriv | 2025-06-05 | 2025-06-09 | 46,000 | — | $0 | 46,000 | SEC↗ |
| Thedinga Angela | Director | A Award deriv | 2025-06-05 | 2025-06-09 | 46,000 | — | $0 | 46,000 | SEC↗ |
| Vratsanos George | Director | A Award deriv | 2025-06-05 | 2025-06-09 | 46,000 | — | $0 | 46,000 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award deriv | 2025-06-05 | 2025-06-09 | 377,000 | — | $0 | 377,000 | SEC↗ |
| Mahmood Nadir | President | A Award deriv | 2025-06-05 | 2025-06-09 | 123,500 | — | $0 | 123,500 | SEC↗ |
| RA Capital Healthcare Fund LP | Director, 10% Owner | A Award deriv | 2025-06-05 | 2025-06-09 | 46,000 | — | $0 | 46,000 | SEC↗ |
| Behbahani Ali | Director | A Award deriv | 2025-06-05 | 2025-06-09 | 46,000 | — | $0 | 46,000 | SEC↗ |
| George Simeon | Director | A Award deriv | 2025-06-05 | 2025-06-09 | 46,000 | — | $0 | 46,000 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | S Sale | 2025-01-15 | 2025-01-17 | 9,584 | $2.20 | $21.1K | 146,735 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2025-01-15 | 2025-01-17 | 17,378 | $2.20 | $38.2K | 319,859 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | S Sale | 2025-01-15 | 2025-01-17 | 7,447 | $2.20 | $16.4K | 124,796 | SEC↗ |
| Levin Alyssa | See Remarks | S Sale | 2025-01-15 | 2025-01-17 | 5,838 | $2.20 | $12.8K | 102,662 | SEC↗ |
| Shook David | See Remarks | S Sale | 2025-01-15 | 2025-01-17 | 8,638 | $2.20 | $19.0K | 190,955 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award deriv | 2025-01-03 | 2025-01-07 | 565,500 | — | $0 | 565,500 | SEC↗ |
| Mahmood Nadir | President | A Award deriv | 2025-01-03 | 2025-01-07 | 123,500 | — | $0 | 123,500 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | A Award deriv | 2025-01-03 | 2025-01-07 | 105,000 | — | $0 | 105,000 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | A Award deriv | 2025-01-03 | 2025-01-07 | 105,000 | — | $0 | 105,000 | SEC↗ |
| Levin Alyssa | See Remarks | A Award deriv | 2025-01-03 | 2025-01-07 | 105,000 | — | $0 | 105,000 | SEC↗ |
| Shook David | See Remarks | A Award deriv | 2025-01-03 | 2025-01-07 | 117,500 | — | $0 | 117,500 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award | 2025-01-03 | 2025-01-07 | 94,500 | — | $0 | 337,237 | SEC↗ |
| Mahmood Nadir | President | A Award | 2025-01-03 | 2025-01-07 | 62,000 | — | $0 | 93,376 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | A Award | 2025-01-03 | 2025-01-07 | 52,500 | — | $0 | 156,319 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | A Award | 2025-01-03 | 2025-01-07 | 52,500 | — | $0 | 132,243 | SEC↗ |
| Levin Alyssa | See Remarks | A Award | 2025-01-03 | 2025-01-07 | 52,500 | — | $0 | 108,500 | SEC↗ |
| Shook David | See Remarks | A Award | 2025-01-03 | 2025-01-07 | 59,000 | — | $0 | 199,593 | SEC↗ |
| Shook David | See Remarks | A Award | 2024-08-21 | 2024-08-23 | 1,352 | $5.11 | $6.9K | 138,593 | SEC↗ |
| Mahmood Nadir | President | A Award deriv | 2024-07-29 | 2024-07-31 | 550,000 | — | $0 | 550,000 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | S Sale | 2024-07-16 | 2024-07-18 | 3,396 | $8.00 | $27.2K | 103,819 | SEC↗ |
| Shook David | See Remarks | A Award deriv | 2024-07-15 | 2024-07-31 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Shook David | See Remarks | A Award | 2024-07-15 | 2024-07-31 | 23,421 | — | $0 | 139,945 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | S Sale | 2024-06-18 | 2024-06-20 | 229 | $5.60 | $1.3K | 79,743 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | S Sale | 2024-06-18 | 2024-06-20 | 727 | $5.60 | $4.1K | 107,215 | SEC↗ |
| Shook David | Chief Medical Officer | S Sale | 2024-06-18 | 2024-06-20 | 456 | $5.60 | $2.6K | 116,524 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2024-06-18 | 2024-06-20 | 1,770 | $5.60 | $9.9K | 240,737 | SEC↗ |
| Trager James | Chief Scientific Officer | S Sale | 2024-06-18 | 2024-06-20 | 456 | $5.60 | $2.6K | 150,959 | SEC↗ |
| Vratsanos George | Director | A Award deriv | 2024-06-13 | 2024-06-14 | 45,000 | — | $0 | 45,000 | SEC↗ |
| Thedinga Angela | Director | A Award deriv | 2024-06-13 | 2024-06-14 | 22,500 | — | $0 | 22,500 | SEC↗ |
| Dybbs Michael | Director | A Award deriv | 2024-06-13 | 2024-06-14 | 22,500 | — | $0 | 22,500 | SEC↗ |
| PATTERSON LEONE D | Director | A Award deriv | 2024-06-13 | 2024-06-14 | 22,500 | — | $0 | 22,500 | SEC↗ |
| Scheiner Zachary | Director | A Award deriv | 2024-06-13 | 2024-06-14 | 22,500 | — | $0 | 22,500 | SEC↗ |
| RA CAPITAL MANAGEMENT, L.P. | Director, 10% Owner | A Award deriv | 2024-06-13 | 2024-06-14 | 22,500 | — | $0 | 22,500 | SEC↗ |
| George Simeon | Director | A Award deriv | 2024-06-13 | 2024-06-14 | 22,500 | — | $0 | 22,500 | SEC↗ |
| Behbahani Ali | Director | A Award deriv | 2024-06-13 | 2024-06-14 | 22,500 | — | $0 | 22,500 | SEC↗ |
| RA CAPITAL MANAGEMENT, L.P. | Director, 10% Owner | P Buy deriv | 2024-03-27 | 2024-03-29 | 3,000,031 | $10.00 | $30.00M | 3,000,031 | SEC↗ |
| George Simeon | Director | P Buy | 2024-03-27 | 2024-03-28 | 451,659 | $10.00 | $4.52M | 451,659 | SEC↗ |
| George Simeon | Director | P Buy | 2024-03-27 | 2024-03-28 | 1,548,341 | $10.00 | $15.48M | 1,548,341 | SEC↗ |
| RA CAPITAL MANAGEMENT, L.P. | Director, 10% Owner | P Buy | 2024-03-27 | 2024-03-29 | 3,000,000 | $10.00 | $30.00M | 10,050,818 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | D To issuer | 2024-03-04 | 2024-03-05 | 137,642 | $13.33 | $1.83M | 240,507 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise deriv | 2024-03-01 | 2024-03-05 | 2,955 | — | $0 | 25,629 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise deriv | 2024-03-01 | 2024-03-05 | 3,808 | — | $0 | 22,445 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise | 2024-03-01 | 2024-03-05 | 2,955 | $3.89 | $11.5K | 88,339 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise | 2024-03-01 | 2024-03-05 | 3,808 | $3.89 | $14.8K | 85,384 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | S Sale | 2024-03-01 | 2024-03-05 | 8,367 | $12.51 | $104.7K | 79,972 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | D To issuer | 2024-03-01 | 2024-03-05 | 12,358 | $13.00 | $160.7K | 378,149 | SEC↗ |
| Trager James | Chief Scientific Officer | S Sale | 2024-02-12 | 2024-02-14 | 4,143 | $12.00 | $49.7K | 149,415 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | S Sale | 2024-01-16 | 2024-01-18 | 4,554 | $8.74 | $39.8K | 107,942 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2024-01-16 | 2024-01-18 | 9,697 | $8.74 | $84.8K | 390,507 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | S Sale | 2024-01-16 | 2024-01-18 | 2,512 | $8.74 | $22.0K | 81,576 | SEC↗ |
| Trager James | Chief Scientific Officer | S Sale | 2024-01-16 | 2024-01-18 | 4,560 | $8.74 | $39.9K | 153,558 | SEC↗ |
| Shook David | Chief Medical Officer | S Sale | 2024-01-16 | 2024-01-18 | 3,552 | $8.74 | $31.0K | 114,980 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | A Award deriv | 2024-01-04 | 2024-01-08 | 112,500 | — | $0 | 112,500 | SEC↗ |
| Levin Alyssa | See Remarks | A Award deriv | 2024-01-04 | 2024-01-08 | 112,500 | — | $0 | 112,500 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award deriv | 2024-01-04 | 2024-01-08 | 509,500 | — | $0 | 509,500 | SEC↗ |
| Trager James | Chief Scientific Officer | A Award deriv | 2024-01-04 | 2024-01-08 | 112,500 | — | $0 | 112,500 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | A Award deriv | 2024-01-04 | 2024-01-08 | 112,500 | — | $0 | 112,500 | SEC↗ |
| Shook David | Chief Medical Officer | A Award deriv | 2024-01-04 | 2024-01-08 | 112,500 | — | $0 | 112,500 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | A Award | 2024-01-04 | 2024-01-08 | 56,000 | — | $0 | 112,496 | SEC↗ |
| Levin Alyssa | See Remarks | A Award | 2024-01-04 | 2024-01-08 | 56,000 | — | $0 | 56,000 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award | 2024-01-04 | 2024-01-08 | 85,000 | — | $0 | 400,204 | SEC↗ |
| Trager James | Chief Scientific Officer | A Award | 2024-01-04 | 2024-01-08 | 56,000 | — | $0 | 158,118 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | A Award | 2024-01-04 | 2024-01-08 | 56,000 | — | $0 | 84,088 | SEC↗ |
| Shook David | Chief Medical Officer | A Award | 2024-01-04 | 2024-01-08 | 56,000 | — | $0 | 118,532 | SEC↗ |
| Shook David | Chief Medical Officer | S Sale | 2023-08-21 | 2023-08-23 | 1,331 | $1.83 | $2.4K | 60,532 | SEC↗ |
| Shook David | Chief Medical Officer | A Award deriv | 2023-07-01 | 2023-07-05 | 208,000 | — | $0 | 208,000 | SEC↗ |
| Levin Alyssa | See Remarks | A Award deriv | 2023-07-01 | 2023-07-05 | 442,400 | — | $0 | 442,400 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2023-06-20 | 2023-06-22 | 1,704 | $4.85 | $8.3K | 313,402 | SEC↗ |
| Mahmood Nadir | See Remarks | S Sale | 2023-06-20 | 2023-06-22 | 526 | $4.85 | $2.6K | 85,776 | SEC↗ |
| Shook David | Chief Medical Officer | S Sale | 2023-06-20 | 2023-06-22 | 439 | $4.85 | $2.1K | 61,863 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | S Sale | 2023-06-20 | 2023-06-22 | 701 | $4.85 | $3.4K | 56,496 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | S Sale | 2023-06-20 | 2023-06-22 | 221 | $4.85 | $1.1K | 28,088 | SEC↗ |
| Trager James | Chief Scientific Officer | S Sale | 2023-06-20 | 2023-06-22 | 439 | $4.85 | $2.1K | 100,118 | SEC↗ |
| Scheiner Zachary | Director | A Award deriv | 2023-06-07 | 2023-06-09 | 22,500 | — | $0 | 22,500 | SEC↗ |
| Azzam Fouad Oscar | Director | A Award deriv | 2023-06-07 | 2023-06-09 | 22,500 | — | $0 | 22,500 | SEC↗ |
| Dybbs Michael | Director | A Award deriv | 2023-06-07 | 2023-06-09 | 22,500 | — | $0 | 22,500 | SEC↗ |
| PATTERSON LEONE D | Director | A Award deriv | 2023-06-07 | 2023-06-09 | 22,500 | — | $0 | 22,500 | SEC↗ |
| Thedinga Angela | Director | A Award deriv | 2023-06-07 | 2023-06-09 | 22,500 | — | $0 | 22,500 | SEC↗ |
| RA Capital Healthcare Fund LP | Director, 10% Owner | A Award deriv | 2023-06-07 | 2023-06-09 | 22,500 | — | $0 | 22,500 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | S Sale | 2023-01-17 | 2023-01-18 | 491 | $5.49 | $2.7K | 28,309 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | S Sale | 2023-01-17 | 2023-01-18 | 1,103 | $5.49 | $6.1K | 57,197 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2023-01-17 | 2023-01-18 | 3,691 | $5.49 | $20.3K | 313,106 | SEC↗ |
| Mahmood Nadir | See Remarks | S Sale | 2023-01-17 | 2023-01-18 | 1,122 | $5.49 | $6.2K | 84,302 | SEC↗ |
| Shook David | Chief Medical Officer | S Sale | 2023-01-17 | 2023-01-18 | 175 | $5.49 | $961 | 60,302 | SEC↗ |
| Trager James | Chief Scientific Officer | S Sale | 2023-01-17 | 2023-01-18 | 1,115 | $5.49 | $6.1K | 98,557 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | A Award deriv | 2023-01-13 | 2023-01-18 | 42,000 | — | $0 | 42,000 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | A Award deriv | 2023-01-13 | 2023-01-18 | 75,000 | — | $0 | 75,000 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award deriv | 2023-01-13 | 2023-01-18 | 386,500 | — | $0 | 386,500 | SEC↗ |
| Mahmood Nadir | See Remarks | A Award deriv | 2023-01-13 | 2023-01-18 | 75,000 | — | $0 | 75,000 | SEC↗ |
| Shook David | Chief Medical Officer | A Award deriv | 2023-01-13 | 2023-01-18 | 75,000 | — | $0 | 75,000 | SEC↗ |
| Trager James | Chief Scientific Officer | A Award deriv | 2023-01-13 | 2023-01-18 | 75,000 | — | $0 | 75,000 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | A Award | 2023-01-13 | 2023-01-18 | 21,000 | — | $0 | 28,800 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | A Award | 2023-01-13 | 2023-01-18 | 37,500 | — | $0 | 58,300 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award | 2023-01-13 | 2023-01-18 | 64,500 | — | $0 | 316,797 | SEC↗ |
| Mahmood Nadir | See Remarks | A Award | 2023-01-13 | 2023-01-18 | 37,500 | — | $0 | 85,424 | SEC↗ |
| Shook David | Chief Medical Officer | A Award | 2023-01-13 | 2023-01-18 | 37,500 | — | $0 | 60,477 | SEC↗ |
| Trager James | Chief Scientific Officer | A Award | 2023-01-13 | 2023-01-18 | 37,500 | — | $0 | 99,672 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise deriv | 2022-10-06 | 2022-10-07 | 842 | — | $0 | 28,584 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise | 2022-10-06 | 2022-10-07 | 842 | $3.89 | $3.3K | 8,642 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | S Sale | 2022-10-06 | 2022-10-07 | 842 | $14.02 | $11.8K | 7,800 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2022-09-29 | 2022-09-30 | 498 | $13.00 | $6.5K | 250,461 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2022-09-28 | 2022-09-30 | 23,376 | $13.03 | $304.6K | 250,959 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2022-09-21 | 2022-09-22 | 6,126 | $13.01 | $79.7K | 274,335 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise deriv | 2022-08-15 | 2022-08-17 | 4,819 | — | $0 | 27,703 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise deriv | 2022-08-15 | 2022-08-17 | 2,681 | — | $0 | 68,062 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise deriv | 2022-08-15 | 2022-08-17 | 11,000 | — | $0 | 26,253 | SEC↗ |
| Trager James | Chief Scientific Officer | M Exercise deriv | 2022-08-15 | 2022-08-17 | 5,000 | — | $0 | 88,243 | SEC↗ |
| Mahmood Nadir | See Remarks | S Sale | 2022-08-15 | 2022-08-17 | 7,500 | $18.03 | $135.2K | 46,088 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise | 2022-08-15 | 2022-08-17 | 7,500 | $3.89 | $29.2K | 53,588 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise | 2022-08-15 | 2022-08-17 | 11,000 | $3.89 | $42.8K | 18,800 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | S Sale | 2022-08-15 | 2022-08-17 | 11,000 | $17.64 | $194.0K | 7,800 | SEC↗ |
| Trager James | Chief Scientific Officer | M Exercise | 2022-08-15 | 2022-08-17 | 5,000 | $3.89 | $19.4K | 67,172 | SEC↗ |
| Trager James | Chief Scientific Officer | S Sale | 2022-08-15 | 2022-08-17 | 5,000 | $17.53 | $87.7K | 62,172 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise deriv | 2022-08-08 | 2022-08-10 | 7,500 | — | $0 | 32,522 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise deriv | 2022-08-08 | 2022-08-10 | 6,886 | — | $0 | 37,253 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise deriv | 2022-08-08 | 2022-08-10 | 340 | — | $0 | 8,445 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise deriv | 2022-08-08 | 2022-08-10 | 4,367 | — | $0 | 0 | SEC↗ |
| Mahmood Nadir | See Remarks | S Sale | 2022-08-08 | 2022-08-10 | 7,500 | $15.32 | $114.9K | 46,088 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise | 2022-08-08 | 2022-08-10 | 7,500 | $3.89 | $29.2K | 53,588 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise | 2022-08-08 | 2022-08-10 | 6,886 | $3.89 | $26.8K | 19,053 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | S Sale | 2022-08-08 | 2022-08-10 | 11,593 | $15.51 | $179.8K | 7,800 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise | 2022-08-08 | 2022-08-10 | 4,367 | $0.41 | $1.8K | 12,167 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise | 2022-08-08 | 2022-08-10 | 340 | $4.77 | $1.6K | 19,393 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise deriv | 2022-07-25 | 2022-07-26 | 7,500 | — | $0 | 63,243 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise deriv | 2022-07-25 | 2022-07-26 | 3,000 | — | $0 | 4,367 | SEC↗ |
| Mahmood Nadir | See Remarks | S Sale | 2022-07-25 | 2022-07-26 | 7,500 | $13.40 | $100.5K | 46,088 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise | 2022-07-25 | 2022-07-26 | 7,500 | $3.89 | $29.2K | 53,588 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | M Exercise | 2022-07-25 | 2022-07-26 | 3,000 | $0.41 | $1.2K | 10,800 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | S Sale | 2022-07-25 | 2022-07-26 | 3,000 | $13.41 | $40.2K | 7,800 | SEC↗ |
| Brandenberger Ralph | Chief Technical Officer | A Award deriv | 2022-07-15 | 2022-07-18 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | A Award deriv | 2022-06-17 | 2022-06-21 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Trager James | Chief Scientific Officer | A Award deriv | 2022-06-17 | 2022-06-21 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | A Award deriv | 2022-06-17 | 2022-06-21 | 50,500 | — | $0 | 50,500 | SEC↗ |
| Mahmood Nadir | See Remarks | A Award deriv | 2022-06-17 | 2022-06-21 | 40,000 | — | $0 | 40,000 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award deriv | 2022-06-17 | 2022-06-21 | 120,000 | — | $0 | 120,000 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | A Award | 2022-06-17 | 2022-06-21 | 2,500 | — | $0 | 7,800 | SEC↗ |
| Trager James | Chief Scientific Officer | A Award | 2022-06-17 | 2022-06-21 | 5,000 | — | $0 | 62,172 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | A Award | 2022-06-17 | 2022-06-21 | 8,000 | — | $0 | 20,800 | SEC↗ |
| Mahmood Nadir | See Remarks | A Award | 2022-06-17 | 2022-06-21 | 6,000 | — | $0 | 46,088 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award | 2022-06-17 | 2022-06-21 | 19,500 | — | $0 | 280,461 | SEC↗ |
| Aynechi Tiba | Director | A Award deriv | 2022-06-08 | 2022-06-10 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Azzam Fouad Oscar | Director | A Award deriv | 2022-06-08 | 2022-06-10 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Dybbs Michael | Director | A Award deriv | 2022-06-08 | 2022-06-10 | 16,000 | — | $0 | 16,000 | SEC↗ |
| George Simeon | Director | A Award deriv | 2022-06-08 | 2022-06-10 | 16,000 | — | $0 | 16,000 | SEC↗ |
| PATTERSON LEONE D | Director | A Award deriv | 2022-06-08 | 2022-06-10 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Scheiner Zachary | Director | A Award deriv | 2022-06-08 | 2022-06-10 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Shawver Laura | Director | A Award deriv | 2022-06-08 | 2022-06-10 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Thedinga Angela | Director | A Award deriv | 2022-06-08 | 2022-06-10 | 3,218 | — | $0 | 3,218 | SEC↗ |
| RA Capital Healthcare Fund LP | Director, 10% Owner | A Award deriv | 2022-06-08 | 2022-06-10 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise deriv | 2022-06-03 | 2022-06-07 | 1,358 | — | $0 | 29,426 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise deriv | 2022-06-03 | 2022-06-07 | 2,037 | — | $0 | 44,139 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise deriv | 2022-06-03 | 2022-06-07 | 405 | — | $0 | 8,785 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise deriv | 2022-06-03 | 2022-06-07 | 340 | — | $0 | 7,367 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | S Sale | 2022-06-03 | 2022-06-07 | 4,140 | $15.00 | $62.1K | 5,300 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise | 2022-06-03 | 2022-06-07 | 340 | $0.41 | $139 | 5,640 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise | 2022-06-03 | 2022-06-07 | 405 | $4.77 | $1.9K | 6,045 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise | 2022-06-03 | 2022-06-07 | 1,358 | $3.89 | $5.3K | 7,403 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise | 2022-06-03 | 2022-06-07 | 2,037 | $3.89 | $7.9K | 9,440 | SEC↗ |
| George Simeon | Director | P Buy | 2022-04-28 | 2022-04-29 | 666,667 | $15.00 | $10.00M | 666,667 | SEC↗ |
| George Simeon | Director | P Buy | 2022-04-28 | 2022-04-29 | 666,666 | $15.00 | $10.00M | 666,666 | SEC↗ |
| Shah Rajeev M. | Director, 10% Owner | P Buy | 2022-04-26 | 2022-04-28 | 2,200,000 | $15.00 | $33.00M | 7,805,129 | SEC↗ |
| Thedinga Angela | Director | A Award deriv | 2022-03-28 | 2022-03-29 | 32,000 | — | $0 | 32,000 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | A Award deriv | 2022-01-14 | 2022-01-19 | 31,400 | — | $0 | 31,400 | SEC↗ |
| Trager James | Chief Scientific Officer | A Award deriv | 2022-01-14 | 2022-01-19 | 76,800 | — | $0 | 76,800 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | A Award deriv | 2022-01-14 | 2022-01-19 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | A Award deriv | 2022-01-14 | 2022-01-19 | 76,800 | — | $0 | 76,800 | SEC↗ |
| Rajangam Kanya | Chief Medical Officer | A Award deriv | 2022-01-14 | 2022-01-19 | 76,800 | — | $0 | 76,800 | SEC↗ |
| Mahmood Nadir | See Remarks | A Award deriv | 2022-01-14 | 2022-01-19 | 76,800 | — | $0 | 76,800 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award deriv | 2022-01-14 | 2022-01-19 | 251,100 | — | $0 | 251,100 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | A Award | 2022-01-14 | 2022-01-19 | 5,300 | — | $0 | 5,300 | SEC↗ |
| Trager James | Chief Scientific Officer | A Award | 2022-01-14 | 2022-01-19 | 12,800 | — | $0 | 57,172 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | A Award | 2022-01-14 | 2022-01-19 | 12,800 | — | $0 | 12,800 | SEC↗ |
| Rajangam Kanya | Chief Medical Officer | A Award | 2022-01-14 | 2022-01-19 | 12,800 | — | $0 | 12,800 | SEC↗ |
| Mahmood Nadir | See Remarks | A Award | 2022-01-14 | 2022-01-19 | 12,800 | — | $0 | 40,088 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award | 2022-01-14 | 2022-01-19 | 41,900 | — | $0 | 260,961 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise deriv | 2021-12-01 | 2021-12-03 | 405 | — | $0 | 9,190 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise deriv | 2021-12-01 | 2021-12-03 | 340 | — | $0 | 7,707 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise deriv | 2021-12-01 | 2021-12-03 | 1,358 | — | $0 | 30,784 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise deriv | 2021-12-01 | 2021-12-03 | 2,037 | — | $0 | 46,176 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise | 2021-12-01 | 2021-12-03 | 405 | $4.77 | $1.9K | 745 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise | 2021-12-01 | 2021-12-03 | 340 | $0.41 | $139 | 340 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise | 2021-12-01 | 2021-12-03 | 1,358 | $3.89 | $5.3K | 2,103 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | M Exercise | 2021-12-01 | 2021-12-03 | 2,037 | $3.89 | $7.9K | 4,140 | SEC↗ |
| Brandenberger Ralph | Sr. VP, Technical Operations | S Sale | 2021-12-01 | 2021-12-03 | 4,140 | $15.64 | $64.7K | 0 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2021-09-29 | 2021-10-01 | 223 | $26.53 | $5.9K | 219,061 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2021-09-29 | 2021-10-01 | 8,277 | $27.20 | $225.1K | 219,284 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise deriv | 2021-09-01 | 2021-09-02 | 2,037 | — | $0 | 48,213 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise deriv | 2021-09-01 | 2021-09-02 | 1,358 | — | $0 | 32,142 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise deriv | 2021-09-01 | 2021-09-02 | 405 | — | $0 | 9,595 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise deriv | 2021-09-01 | 2021-09-02 | 340 | — | $0 | 8,047 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise | 2021-09-01 | 2021-09-02 | 405 | $4.77 | $1.9K | 745 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise | 2021-09-01 | 2021-09-02 | 2,037 | $3.89 | $7.9K | 4,140 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise | 2021-09-01 | 2021-09-02 | 340 | $0.41 | $139 | 340 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise | 2021-09-01 | 2021-09-02 | 1,358 | $3.89 | $5.3K | 2,103 | SEC↗ |
| Brandenberger Ralph | See Remarks | S Sale | 2021-09-01 | 2021-09-02 | 4,140 | $32.08 | $132.8K | 0 | SEC↗ |
| Rajangam Kanya | Chief Medical Officer | M Exercise deriv | 2021-08-05 | 2021-08-09 | 10,000 | — | $0 | 44,054 | SEC↗ |
| Rajangam Kanya | Chief Medical Officer | S Sale | 2021-08-05 | 2021-08-09 | 10,000 | $37.28 | $372.8K | 0 | SEC↗ |
| Rajangam Kanya | Chief Medical Officer | M Exercise | 2021-08-05 | 2021-08-09 | 10,000 | $0.41 | $4.1K | 10,000 | SEC↗ |
| Trager James | Chief Scientific Officer | M Exercise deriv | 2021-08-02 | 2021-08-04 | 2,250 | — | $0 | 55,412 | SEC↗ |
| Trager James | Chief Scientific Officer | S Sale | 2021-08-02 | 2021-08-04 | 3,600 | $31.53 | $113.5K | 44,372 | SEC↗ |
| Trager James | Chief Scientific Officer | M Exercise | 2021-08-02 | 2021-08-04 | 2,250 | $3.89 | $8.8K | 47,972 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise deriv | 2021-07-01 | 2021-07-06 | 3,500 | — | $0 | 70,743 | SEC↗ |
| Mahmood Nadir | See Remarks | S Sale | 2021-07-01 | 2021-07-06 | 6,500 | $31.71 | $206.1K | 27,288 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise | 2021-07-01 | 2021-07-06 | 3,500 | $3.89 | $13.6K | 33,788 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2021-06-21 | 2021-06-23 | 3,807 | $26.89 | $102.4K | 227,561 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2021-06-21 | 2021-06-23 | 4,693 | $26.39 | $123.8K | 231,368 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise deriv | 2021-06-16 | 2021-06-17 | 1,800 | — | $0 | 47,522 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise | 2021-06-16 | 2021-06-17 | 1,800 | $3.89 | $7.0K | 30,288 | SEC↗ |
| Azzam Fouad Oscar | Director | A Award deriv | 2021-06-13 | 2021-06-15 | 16,511 | — | $0 | 16,511 | SEC↗ |
| Shawver Laura | Director | A Award deriv | 2021-06-13 | 2021-06-15 | 16,511 | — | $0 | 16,511 | SEC↗ |
| PATTERSON LEONE D | Director | A Award deriv | 2021-06-13 | 2021-06-15 | 16,511 | — | $0 | 16,511 | SEC↗ |
| Scheiner Zachary | Director | A Award deriv | 2021-06-13 | 2021-06-15 | 16,511 | — | $0 | 16,511 | SEC↗ |
| Dybbs Michael | Director | A Award deriv | 2021-06-13 | 2021-06-15 | 16,511 | — | $0 | 16,511 | SEC↗ |
| George Simeon | Director | A Award deriv | 2021-06-13 | 2021-06-15 | 16,511 | — | $0 | 16,511 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise deriv | 2021-06-02 | 2021-06-04 | 2,037 | — | $0 | 50,250 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise deriv | 2021-06-02 | 2021-06-04 | 1,358 | — | $0 | 33,500 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise deriv | 2021-06-02 | 2021-06-04 | 405 | — | $0 | 10,000 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise deriv | 2021-06-02 | 2021-06-04 | 340 | — | $0 | 8,387 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise | 2021-06-02 | 2021-06-04 | 1,358 | $3.89 | $5.3K | 2,103 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise | 2021-06-02 | 2021-06-04 | 405 | $4.77 | $1.9K | 745 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise | 2021-06-02 | 2021-06-04 | 340 | $0.41 | $139 | 340 | SEC↗ |
| Brandenberger Ralph | See Remarks | M Exercise | 2021-06-02 | 2021-06-04 | 2,037 | $3.89 | $7.9K | 4,140 | SEC↗ |
| Brandenberger Ralph | See Remarks | S Sale | 2021-06-02 | 2021-06-04 | 4,140 | $24.50 | $101.4K | 0 | SEC↗ |
| Mahmood Nadir | See Remarks | S Sale | 2021-05-10 | 2021-05-12 | 3,000 | $27.16 | $81.5K | 28,488 | SEC↗ |
| Trager James | Chief Scientific Officer | M Exercise deriv | 2021-05-03 | 2021-05-05 | 2,250 | — | $0 | 57,662 | SEC↗ |
| Trager James | Chief Scientific Officer | M Exercise | 2021-05-03 | 2021-05-05 | 2,250 | $3.89 | $8.8K | 47,972 | SEC↗ |
| Trager James | Chief Scientific Officer | S Sale | 2021-05-03 | 2021-05-05 | 2,250 | $31.64 | $71.2K | 45,722 | SEC↗ |
| Trager James | Chief Scientific Officer | S Sale | 2021-05-03 | 2021-05-05 | 1,350 | $31.64 | $42.7K | 45,722 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise deriv | 2021-04-01 | 2021-04-02 | 3,500 | — | $0 | 74,243 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise | 2021-04-01 | 2021-04-02 | 3,500 | $3.89 | $13.6K | 34,988 | SEC↗ |
| Mahmood Nadir | See Remarks | S Sale | 2021-04-01 | 2021-04-02 | 3,500 | $32.70 | $114.5K | 31,488 | SEC↗ |
| Shah Rajeev M. | 10% Owner | J Other | 2021-04-01 | 2021-04-05 | 307,214 | $32.90 | $10.11M | 4,589,999 | SEC↗ |
| Shah Rajeev M. | 10% Owner | J Other | 2021-04-01 | 2021-04-05 | 260,819 | $32.90 | $8.58M | 260,819 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2021-03-30 | 2021-04-01 | 3,130 | $32.21 | $100.8K | 236,061 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2021-03-30 | 2021-04-01 | 11,461 | $30.23 | $346.5K | 241,600 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | S Sale | 2021-03-30 | 2021-04-01 | 2,409 | $31.24 | $75.3K | 239,191 | SEC↗ |
| Trager James | Chief Scientific Officer | M Exercise deriv | 2021-02-02 | 2021-02-03 | 2,800 | — | $0 | 79,600 | SEC↗ |
| Trager James | Chief Scientific Officer | M Exercise | 2021-02-02 | 2021-02-03 | 2,800 | $18.00 | $50.4K | 49,872 | SEC↗ |
| Trager James | Chief Scientific Officer | S Sale | 2021-02-02 | 2021-02-03 | 2,800 | $40.00 | $112.0K | 47,072 | SEC↗ |
| Trager James | Chief Scientific Officer | M Exercise deriv | 2021-02-01 | 2021-02-03 | 2,250 | — | $0 | 59,912 | SEC↗ |
| Trager James | Chief Scientific Officer | S Sale | 2021-02-01 | 2021-02-03 | 1,566 | $39.46 | $61.8K | 47,072 | SEC↗ |
| Trager James | Chief Scientific Officer | S Sale | 2021-02-01 | 2021-02-03 | 2,034 | $38.07 | $77.4K | 48,638 | SEC↗ |
| Trager James | Chief Scientific Officer | M Exercise | 2021-02-01 | 2021-02-03 | 2,250 | $3.89 | $8.8K | 50,672 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise deriv | 2021-01-25 | 2021-01-26 | 5,500 | — | $0 | 77,743 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise | 2021-01-25 | 2021-01-26 | 5,500 | $3.89 | $21.4K | 36,988 | SEC↗ |
| Mahmood Nadir | See Remarks | S Sale | 2021-01-25 | 2021-01-26 | 2,000 | $48.86 | $97.7K | 34,988 | SEC↗ |
| Mahmood Nadir | See Remarks | S Sale | 2021-01-25 | 2021-01-26 | 3,500 | $48.40 | $169.4K | 31,488 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise deriv | 2021-01-14 | 2021-01-19 | 3,083 | — | $0 | 49,322 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise | 2021-01-14 | 2021-01-19 | 3,083 | $3.89 | $12.0K | 31,488 | SEC↗ |
| Trager James | Chief Scientific Officer | A Award deriv | 2021-01-08 | 2021-01-12 | 52,500 | — | $0 | 52,500 | SEC↗ |
| Chief Legal Officer | A Award deriv | 2021-01-08 | 2021-01-12 | 13,125 | — | $0 | 13,125 | SEC↗ | |
| Mahmood Nadir | See Remarks | A Award deriv | 2021-01-08 | 2021-01-12 | 52,500 | — | $0 | 52,500 | SEC↗ |
| HASTINGS PAUL J | Chief Executive Officer | A Award deriv | 2021-01-08 | 2021-01-12 | 157,500 | — | $0 | 157,500 | SEC↗ |
| Rajangam Kanya | Chief Medical Officer | A Award deriv | 2021-01-08 | 2021-01-12 | 52,500 | — | $0 | 52,500 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise deriv | 2020-12-03 | 2020-12-07 | 3,000 | — | $0 | 52,405 | SEC↗ |
| Mahmood Nadir | See Remarks | M Exercise | 2020-12-03 | 2020-12-07 | 3,000 | $3.89 | $11.7K | 28,405 | SEC↗ |
| Hager Alicia J. | Chief Legal Officer | A Award deriv | 2020-10-26 | 2020-10-28 | 150,000 | — | $0 | 150,000 | SEC↗ |
| Mahmood Nadir | See Remarks | A Award deriv | 2020-10-02 | 2020-10-05 | 50,000 | — | $0 | 50,000 | SEC↗ |
| Mahmood Nadir | See Remarks | A Award deriv | 2020-10-02 | 2020-12-03 | 50,000 | — | $0 | 50,000 | SEC↗ |
| Deerfield Mgmt IV, L.P. | 10% Owner | C Conversion deriv | 2020-07-14 | 2020-07-14 | 2,626,767 | — | $0 | 0 | SEC↗ |
| Deerfield Mgmt IV, L.P. | 10% Owner | C Conversion deriv | 2020-07-14 | 2020-07-14 | 2,626,767 | — | $0 | 0 | SEC↗ |
| Shah Rajeev M. | 10% Owner | C Conversion deriv | 2020-07-14 | 2020-07-16 | 8,405,656 | — | $0 | 0 | SEC↗ |
| Novo Holdings A/S | 10% Owner | C Conversion deriv | 2020-07-14 | 2020-07-16 | 525,499 | — | $0 | 0 | SEC↗ |
| Novo Holdings A/S | 10% Owner | C Conversion deriv | 2020-07-14 | 2020-07-16 | 1,712,811 | — | $0 | 0 | SEC↗ |
| GLAXOSMITHKLINE PLC | Director, 10% Owner | A Award deriv | 2020-07-14 | 2020-07-16 | 10,700 | — | $0 | 10,700 | SEC↗ |
| GLAXOSMITHKLINE PLC | Director, 10% Owner | C Conversion deriv | 2020-07-14 | 2020-07-16 | 292,663 | — | $0 | 0 | SEC↗ |
| GLAXOSMITHKLINE PLC | Director, 10% Owner | C Conversion deriv | 2020-07-14 | 2020-07-16 | 1,994,348 | — | $0 | 0 | SEC↗ |
| GLAXOSMITHKLINE PLC | Director, 10% Owner | C Conversion deriv | 2020-07-14 | 2020-07-16 | 6,337,403 | — | $0 | 0 | SEC↗ |
| Deerfield Mgmt IV, L.P. | 10% Owner | P Buy | 2020-07-14 | 2020-07-14 | 500,000 | $18.00 | $9.00M | 1,209,936 | SEC↗ |
| Deerfield Mgmt IV, L.P. | 10% Owner | P Buy | 2020-07-14 | 2020-07-14 | 500,000 | $18.00 | $9.00M | 1,209,936 | SEC↗ |
| Deerfield Mgmt IV, L.P. | 10% Owner | C Conversion | 2020-07-14 | 2020-07-14 | 709,936 | — | $0 | 709,936 | SEC↗ |