NUVL

Nuvalent, Inc.CIK 1861560 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for NUVL PRO

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AI insights for NUVL

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Lane Benjamin	See Remarks	13	$0	$0	2026-07-15
Pelish Henry E.	Chief Scientific Officer	132	$0	$13.24M	2026-07-15
Miller Deborah Ann	Chief Legal Officer	221	$0	$23.79M	2026-07-15
Porter James Richard	President and CEO	130	$0	$47.90M	2026-07-15
Noci Darlene	See Remarks	286	$0	$26.59M	2026-07-15
Balcom Alexandra	Chief Financial Officer	164	$0	$30.97M	2026-07-15
Turner Christopher Durant	Chief Medical Officer	54	$0	$2.19M	2026-07-15
Oliger Christy J.	Director	6	$0	$0	2026-07-15
Wheeler Cameron	Director	15	$0	$0	2026-07-15
Deerfield Private Design Fund IV, L.P.	Director, 10% Owner	18	$0	$0	2026-07-15
Meyers Michael L.	Director	14	$0	$0	2026-07-15
Bogle Grant C.	Director	9	$0	$0	2026-07-15
Srivastava Sapna	Director	15	$0	$0	2026-07-15
Squarer Ron	Director	5	$0	$0	2026-07-15
Protopapas Anna	Director	18	$0	$378.4K	2026-07-15
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	Director, 10% Owner	11	$0	$0	2026-06-16
Shair Matthew	Director	108	$0	$49.98M	2025-11-24
Flynn James E	Director, 10% Owner	6	$0	$70.88M	2025-11-24
Pearlberg Joseph	Director	7	$0	$0	2025-06-18
Hack Andrew A. F.	Director	12	$17.49M	$174.04M	2024-12-11
Deerfield Mgmt L.P.	Director, 10% Owner	3	$21.77M	$195.50M	2024-10-22
Conley Emily	Director	34	$0	$2.83M	2024-08-23
Gilliland Dwight Gary	Director	5	$0	$0	2024-06-12
Wellington Biomedical Innovation Master Investors (Cayman) I L.P.	10% Owner	2	$0	$0	2021-08-02
Deerfield Healthcare Innovations Fund, L.P.	Director, 10% Owner	14	$10.20M	$0	2021-08-02
Jackson Robert Bowers	Director	1	$0	$0	2021-07-28
Philbin Robert J.	Other	1	$0	$0	2016-12-01
Riess Robert F.	COO & CMO	4	$0	$0	2016-12-01
Resnick Richard P.	Executive VP of Operations	6	$0	$0	2016-12-01
Batchelor David W.	Chief Relations Officer	2	$0	$0	2016-12-01
Peyton Whitney E.	Director, 10% Owner	8	$0	$0	2016-12-01
Hattara Jeffrey J.	Chief Strategy Officer	5	$0	$0	2016-12-01
Dodge Jonathan	Director	1	$0	$0	2016-12-01
Mandel James	President & CEO	5	$0	$0	2016-12-01
MILLER DONALD	Director, 10% Owner	13	$0	$0	2016-12-01
Davenport Colleen M.	General Counsel & Secretary	2	$0	$0	2016-12-01
Carlson David C.	Chief Financial Officer	5	$0	$0	2016-12-01
FAZZOLARI SALVATORE D	Director	6	$0	$0	2016-12-01
PARAGON CAPITAL LP	10% Owner	20	$0	$196.4K	2012-05-09

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Wheeler Cameron	Director	D To issuer deriv	2026-07-15	2026-07-15	3,789	—	$0	0	SEC↗
Wheeler Cameron	Director	D To issuer deriv	2026-07-15	2026-07-15	15,000	—	$0	0	SEC↗
Wheeler Cameron	Director	D To issuer deriv	2026-07-15	2026-07-15	43,000	—	$0	0	SEC↗
Wheeler Cameron	Director	D To issuer deriv	2026-07-15	2026-07-15	4,147	—	$0	0	SEC↗
Wheeler Cameron	Director	D To issuer deriv	2026-07-15	2026-07-15	20,000	—	$0	0	SEC↗
Bogle Grant C.	Director	D To issuer deriv	2026-07-15	2026-07-15	4,147	—	$0	0	SEC↗
Bogle Grant C.	Director	D To issuer deriv	2026-07-15	2026-07-15	4,851	—	$0	0	SEC↗
Protopapas Anna	Director	D To issuer deriv	2026-07-15	2026-07-15	3,789	—	$0	0	SEC↗
Protopapas Anna	Director	D To issuer deriv	2026-07-15	2026-07-15	15,000	—	$0	0	SEC↗
Protopapas Anna	Director	D To issuer deriv	2026-07-15	2026-07-15	15,000	—	$0	0	SEC↗
Protopapas Anna	Director	D To issuer deriv	2026-07-15	2026-07-15	4,147	—	$0	0	SEC↗
Protopapas Anna	Director	D To issuer deriv	2026-07-15	2026-07-15	40,000	—	$0	0	SEC↗
Miller Deborah Ann	Chief Legal Officer	D To issuer deriv	2026-07-15	2026-07-15	72,608	—	$0	0	SEC↗
Miller Deborah Ann	Chief Legal Officer	D To issuer deriv	2026-07-15	2026-07-15	61,000	—	$0	0	SEC↗
Miller Deborah Ann	Chief Legal Officer	D To issuer deriv	2026-07-15	2026-07-15	17,500	—	$0	0	SEC↗
Miller Deborah Ann	Chief Legal Officer	D To issuer deriv	2026-07-15	2026-07-15	75,154	—	$0	0	SEC↗
Miller Deborah Ann	Chief Legal Officer	D To issuer deriv	2026-07-15	2026-07-15	37,500	—	$0	0	SEC↗
Miller Deborah Ann	Chief Legal Officer	D To issuer deriv	2026-07-15	2026-07-15	47,500	—	$0	0	SEC↗
Porter James Richard	President and CEO	D To issuer deriv	2026-07-15	2026-07-15	112,500	—	$0	0	SEC↗
Porter James Richard	President and CEO	D To issuer deriv	2026-07-15	2026-07-15	118,686	—	$0	0	SEC↗
Porter James Richard	President and CEO	D To issuer deriv	2026-07-15	2026-07-15	131,494	—	$0	0	SEC↗
Porter James Richard	President and CEO	D To issuer deriv	2026-07-15	2026-07-15	161,100	—	$0	0	SEC↗
Porter James Richard	President and CEO	D To issuer deriv	2026-07-15	2026-07-15	508,942	—	$0	0	SEC↗
Porter James Richard	President and CEO	D To issuer deriv	2026-07-15	2026-07-15	46,250	—	$0	0	SEC↗
Porter James Richard	President and CEO	D To issuer deriv	2026-07-15	2026-07-15	49,401	—	$0	0	SEC↗
Porter James Richard	President and CEO	D To issuer deriv	2026-07-15	2026-07-15	33,423	—	$0	0	SEC↗
Porter James Richard	President and CEO	D To issuer deriv	2026-07-15	2026-07-15	867,172	—	$0	0	SEC↗
Pelish Henry E.	Chief Scientific Officer	D To issuer deriv	2026-07-15	2026-07-15	3,258	—	$0	0	SEC↗
Pelish Henry E.	Chief Scientific Officer	D To issuer deriv	2026-07-15	2026-07-15	17,500	—	$0	0	SEC↗
Pelish Henry E.	Chief Scientific Officer	D To issuer deriv	2026-07-15	2026-07-15	37,500	—	$0	0	SEC↗
Pelish Henry E.	Chief Scientific Officer	D To issuer deriv	2026-07-15	2026-07-15	18,600	—	$0	0	SEC↗
Pelish Henry E.	Chief Scientific Officer	D To issuer deriv	2026-07-15	2026-07-15	21,073	—	$0	0	SEC↗
Pelish Henry E.	Chief Scientific Officer	D To issuer deriv	2026-07-15	2026-07-15	9,900	—	$0	0	SEC↗
Pelish Henry E.	Chief Scientific Officer	D To issuer deriv	2026-07-15	2026-07-15	8,309	—	$0	0	SEC↗
Pelish Henry E.	Chief Scientific Officer	D To issuer deriv	2026-07-15	2026-07-15	2,113	—	$0	0	SEC↗
Lane Benjamin	See Remarks	D To issuer deriv	2026-07-15	2026-07-15	15,052	—	$0	0	SEC↗
Lane Benjamin	See Remarks	D To issuer deriv	2026-07-15	2026-07-15	12,025	—	$0	0	SEC↗
Lane Benjamin	See Remarks	D To issuer deriv	2026-07-15	2026-07-15	8,000	—	$0	0	SEC↗
Lane Benjamin	See Remarks	D To issuer deriv	2026-07-15	2026-07-15	17,848	—	$0	0	SEC↗
Lane Benjamin	See Remarks	D To issuer deriv	2026-07-15	2026-07-15	8,333	—	$0	0	SEC↗
Lane Benjamin	See Remarks	D To issuer deriv	2026-07-15	2026-07-15	731	—	$0	0	SEC↗
Lane Benjamin	See Remarks	D To issuer deriv	2026-07-15	2026-07-15	19,000	—	$0	0	SEC↗
Noci Darlene	Chief Development Officer	D To issuer deriv	2026-07-15	2026-07-15	33,646	—	$0	0	SEC↗
Noci Darlene	Chief Development Officer	D To issuer deriv	2026-07-15	2026-07-15	37,500	—	$0	0	SEC↗
Noci Darlene	Chief Development Officer	D To issuer deriv	2026-07-15	2026-07-15	81,329	—	$0	0	SEC↗
Noci Darlene	Chief Development Officer	D To issuer deriv	2026-07-15	2026-07-15	21,259	—	$0	0	SEC↗
Noci Darlene	Chief Development Officer	D To issuer deriv	2026-07-15	2026-07-15	15,112	—	$0	0	SEC↗
Noci Darlene	Chief Development Officer	D To issuer deriv	2026-07-15	2026-07-15	216	—	$0	0	SEC↗
Noci Darlene	Chief Development Officer	D To issuer deriv	2026-07-15	2026-07-15	6,091	—	$0	0	SEC↗
Noci Darlene	Chief Development Officer	D To issuer deriv	2026-07-15	2026-07-15	17,500	—	$0	0	SEC↗
Turner Christopher Durant	Chief Medical Officer	D To issuer deriv	2026-07-15	2026-07-15	37,500	—	$0	0	SEC↗
Turner Christopher Durant	Chief Medical Officer	D To issuer deriv	2026-07-15	2026-07-15	47,500	—	$0	0	SEC↗
Turner Christopher Durant	Chief Medical Officer	D To issuer deriv	2026-07-15	2026-07-15	303,105	—	$0	0	SEC↗
Turner Christopher Durant	Chief Medical Officer	D To issuer deriv	2026-07-15	2026-07-15	17,500	—	$0	0	SEC↗
Turner Christopher Durant	Chief Medical Officer	D To issuer deriv	2026-07-15	2026-07-15	144,200	—	$0	0	SEC↗
Turner Christopher Durant	Chief Medical Officer	D To issuer deriv	2026-07-15	2026-07-15	107,000	—	$0	0	SEC↗
Turner Christopher Durant	Chief Medical Officer	D To issuer deriv	2026-07-15	2026-07-15	2,835	—	$0	0	SEC↗
Squarer Ron	Director	D To issuer deriv	2026-07-15	2026-07-15	4,418	—	$0	0	SEC↗
Oliger Christy J.	Director	D To issuer deriv	2026-07-15	2026-07-15	6,119	—	$0	0	SEC↗
Srivastava Sapna	Director	D To issuer deriv	2026-07-15	2026-07-15	4,147	—	$0	0	SEC↗
Srivastava Sapna	Director	D To issuer deriv	2026-07-15	2026-07-15	68,500	—	$0	0	SEC↗
Srivastava Sapna	Director	D To issuer deriv	2026-07-15	2026-07-15	20,000	—	$0	0	SEC↗
Srivastava Sapna	Director	D To issuer deriv	2026-07-15	2026-07-15	15,000	—	$0	0	SEC↗
Srivastava Sapna	Director	D To issuer deriv	2026-07-15	2026-07-15	3,789	—	$0	0	SEC↗
Balcom Alexandra	Chief Financial Officer	D To issuer deriv	2026-07-15	2026-07-15	22,933	—	$0	0	SEC↗
Balcom Alexandra	Chief Financial Officer	D To issuer deriv	2026-07-15	2026-07-15	131,637	—	$0	0	SEC↗
Balcom Alexandra	Chief Financial Officer	D To issuer deriv	2026-07-15	2026-07-15	8,016	—	$0	0	SEC↗
Balcom Alexandra	Chief Financial Officer	D To issuer deriv	2026-07-15	2026-07-15	84,200	—	$0	0	SEC↗
Balcom Alexandra	Chief Financial Officer	D To issuer deriv	2026-07-15	2026-07-15	33,646	—	$0	0	SEC↗
Balcom Alexandra	Chief Financial Officer	D To issuer deriv	2026-07-15	2026-07-15	17,500	—	$0	0	SEC↗
Balcom Alexandra	Chief Financial Officer	D To issuer deriv	2026-07-15	2026-07-15	37,500	—	$0	0	SEC↗
Meyers Michael L.	Director	D To issuer deriv	2026-07-15	2026-07-15	8,361	—	$0	0	SEC↗
Meyers Michael L.	Director	D To issuer deriv	2026-07-15	2026-07-15	40,000	—	$0	0	SEC↗
Meyers Michael L.	Director	D To issuer deriv	2026-07-15	2026-07-15	15,000	—	$0	0	SEC↗
Meyers Michael L.	Director	D To issuer deriv	2026-07-15	2026-07-15	3,789	—	$0	0	SEC↗
Meyers Michael L.	Director	D To issuer deriv	2026-07-15	2026-07-15	4,147	—	$0	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer deriv	2026-07-15	2026-07-17	20,000	—	$0	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer deriv	2026-07-15	2026-07-17	20,000	—	$0	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer deriv	2026-07-15	2026-07-17	43,000	—	$0	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer deriv	2026-07-15	2026-07-17	43,000	—	$0	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer deriv	2026-07-15	2026-07-17	2,717,627	$124.00	$336.99M	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer deriv	2026-07-15	2026-07-17	2,717,627	$124.00	$336.99M	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer deriv	2026-07-15	2026-07-17	15,000	—	$0	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer deriv	2026-07-15	2026-07-17	3,789	—	$0	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer deriv	2026-07-15	2026-07-17	3,789	—	$0	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer deriv	2026-07-15	2026-07-17	4,147	—	$0	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer deriv	2026-07-15	2026-07-17	4,147	—	$0	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer deriv	2026-07-15	2026-07-17	15,000	—	$0	0	SEC↗
Wheeler Cameron	Director	D To issuer	2026-07-15	2026-07-15	3,444	—	$0	0	SEC↗
Wheeler Cameron	Director	U Tender	2026-07-15	2026-07-15	5,146	$124.00	$638.1K	0	SEC↗
Bogle Grant C.	Director	D To issuer	2026-07-15	2026-07-15	5,577	—	$0	0	SEC↗
Bogle Grant C.	Director	U Tender	2026-07-15	2026-07-15	3,714	$124.00	$460.5K	0	SEC↗
Protopapas Anna	Director	U Tender	2026-07-15	2026-07-15	5,146	$124.00	$638.1K	0	SEC↗
Protopapas Anna	Director	D To issuer	2026-07-15	2026-07-15	3,444	—	$0	0	SEC↗
Miller Deborah Ann	Chief Legal Officer	U Tender	2026-07-15	2026-07-15	18,534	$124.00	$2.30M	0	SEC↗
Miller Deborah Ann	Chief Legal Officer	D To issuer	2026-07-15	2026-07-15	14,350	—	$0	0	SEC↗
Miller Deborah Ann	Chief Legal Officer	A Award	2026-07-15	2026-07-15	14,350	—	$0	14,350	SEC↗
Miller Deborah Ann	Chief Legal Officer	D To issuer	2026-07-15	2026-07-15	41,100	—	$0	0	SEC↗
Porter James Richard	President and CEO	D To issuer	2026-07-15	2026-07-15	121,350	—	$0	0	SEC↗
Porter James Richard	President and CEO	U Tender	2026-07-15	2026-07-15	203,529	$124.00	$25.24M	0	SEC↗
Porter James Richard	President and CEO	A Award	2026-07-15	2026-07-15	40,025	—	$0	40,025	SEC↗
Porter James Richard	President and CEO	D To issuer	2026-07-15	2026-07-15	40,025	—	$0	0	SEC↗
Pelish Henry E.	Chief Scientific Officer	A Award	2026-07-15	2026-07-15	14,350	—	$0	14,350	SEC↗
Pelish Henry E.	Chief Scientific Officer	D To issuer	2026-07-15	2026-07-15	14,350	—	$0	0	SEC↗
Pelish Henry E.	Chief Scientific Officer	U Tender	2026-07-15	2026-07-15	22,393	$124.00	$2.78M	0	SEC↗
Pelish Henry E.	Chief Scientific Officer	D To issuer	2026-07-15	2026-07-15	41,100	—	$0	0	SEC↗
Lane Benjamin	See Remarks	D To issuer	2026-07-15	2026-07-15	7,120	—	$0	0	SEC↗
Lane Benjamin	See Remarks	U Tender	2026-07-15	2026-07-15	21,092	$124.00	$2.62M	0	SEC↗
Lane Benjamin	See Remarks	D To issuer	2026-07-15	2026-07-15	29,433	—	$0	0	SEC↗
Lane Benjamin	See Remarks	A Award	2026-07-15	2026-07-15	7,120	—	$0	7,120	SEC↗
Noci Darlene	Chief Development Officer	A Award	2026-07-15	2026-07-15	14,350	—	$0	14,350	SEC↗
Noci Darlene	Chief Development Officer	U Tender	2026-07-15	2026-07-15	17,017	$124.00	$2.11M	0	SEC↗
Noci Darlene	Chief Development Officer	D To issuer	2026-07-15	2026-07-15	14,350	—	$0	0	SEC↗
Noci Darlene	Chief Development Officer	D To issuer	2026-07-15	2026-07-15	41,100	—	$0	0	SEC↗
Turner Christopher Durant	Chief Medical Officer	D To issuer	2026-07-15	2026-07-15	14,350	—	$0	0	SEC↗
Turner Christopher Durant	Chief Medical Officer	U Tender	2026-07-15	2026-07-15	31,530	$124.00	$3.91M	0	SEC↗
Turner Christopher Durant	Chief Medical Officer	A Award	2026-07-15	2026-07-15	14,350	—	$0	14,350	SEC↗
Turner Christopher Durant	Chief Medical Officer	D To issuer	2026-07-15	2026-07-15	41,100	—	$0	0	SEC↗
Squarer Ron	Director	D To issuer	2026-07-15	2026-07-15	6,281	—	$0	0	SEC↗
Oliger Christy J.	Director	U Tender	2026-07-15	2026-07-15	1,324	$124.00	$164.2K	0	SEC↗
Oliger Christy J.	Director	D To issuer	2026-07-15	2026-07-15	6,091	—	$0	0	SEC↗
Srivastava Sapna	Director	U Tender	2026-07-15	2026-07-15	5,146	$124.00	$638.1K	0	SEC↗
Srivastava Sapna	Director	D To issuer	2026-07-15	2026-07-15	3,444	—	$0	0	SEC↗
Balcom Alexandra	Chief Financial Officer	D To issuer	2026-07-15	2026-07-15	41,100	—	$0	0	SEC↗
Balcom Alexandra	Chief Financial Officer	A Award	2026-07-15	2026-07-15	14,350	—	$0	14,350	SEC↗
Balcom Alexandra	Chief Financial Officer	D To issuer	2026-07-15	2026-07-15	14,350	—	$0	0	SEC↗
Balcom Alexandra	Chief Financial Officer	U Tender	2026-07-15	2026-07-15	44,433	$124.00	$5.51M	0	SEC↗
Meyers Michael L.	Director	D To issuer	2026-07-15	2026-07-15	3,444	—	$0	0	SEC↗
Meyers Michael L.	Director	U Tender	2026-07-15	2026-07-15	5,146	$124.00	$638.1K	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer	2026-07-15	2026-07-17	8,299,225	$124.00	$1.03B	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer	2026-07-15	2026-07-17	8,299,225	$124.00	$1.03B	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer	2026-07-15	2026-07-17	650,000	$124.00	$80.60M	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	U Tender	2026-07-15	2026-07-17	5,146	$124.00	$638.1K	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	D To issuer	2026-07-15	2026-07-17	3,444	$124.00	$427.1K	0	SEC↗
Deerfield Private Design Fund	Director, 10% Owner	U Tender	2026-07-15	2026-07-17	5,146	$124.00	$638.1K	0	SEC↗
Pelish Henry E.	Chief Scientific Officer	S Sale	2026-07-09	2026-07-10	2,111	$123.81	$261.4K	63,493	SEC↗
Porter James Richard	President and CEO	M Exercise deriv	2026-07-06	2026-07-08	30,000	—	$0	118,686	SEC↗
Porter James Richard	President and CEO	M Exercise	2026-07-06	2026-07-08	30,000	$18.93	$567.9K	354,879	SEC↗
Porter James Richard	President and CEO	S Sale	2026-07-06	2026-07-08	30,000	$123.72	$3.71M	324,879	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise deriv	2026-07-01	2026-07-06	5,384	—	$0	8,016	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise deriv	2026-07-01	2026-07-06	6,046	—	$0	22,933	SEC↗
Noci Darlene	Chief Development Officer	M Exercise deriv	2026-07-01	2026-07-06	9,146	—	$0	15,112	SEC↗
Noci Darlene	Chief Development Officer	M Exercise deriv	2026-07-01	2026-07-06	13,854	—	$0	33,646	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-07-01	2026-07-06	11,430	$123.58	$1.41M	85,533	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise	2026-07-01	2026-07-06	6,046	$18.93	$114.5K	96,963	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise	2026-07-01	2026-07-06	5,384	$6.89	$37.1K	90,917	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-07-01	2026-07-06	23,000	$123.59	$2.84M	58,117	SEC↗
Noci Darlene	Chief Development Officer	M Exercise	2026-07-01	2026-07-06	9,146	$18.93	$173.1K	67,263	SEC↗
Noci Darlene	Chief Development Officer	M Exercise	2026-07-01	2026-07-06	13,854	$72.35	$1.00M	81,117	SEC↗
Noci Darlene	Chief Development Officer	M Exercise deriv	2026-06-29	2026-07-01	5,500	—	$0	81,329	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-06-29	2026-07-01	5,500	$123.51	$679.3K	58,117	SEC↗
Noci Darlene	Chief Development Officer	M Exercise	2026-06-29	2026-07-01	5,500	$27.85	$153.2K	63,617	SEC↗
Bogle Grant C.	Director	A Award	2026-06-16	2026-06-18	3,444	—	$0	9,291	SEC↗
Meyers Michael L.	Director	A Award	2026-06-16	2026-06-18	3,444	—	$0	8,590	SEC↗
Oliger Christy J.	Director	A Award	2026-06-16	2026-06-18	3,444	—	$0	7,415	SEC↗
Protopapas Anna	Director	A Award	2026-06-16	2026-06-18	3,444	—	$0	8,590	SEC↗
Squarer Ron	Director	A Award	2026-06-16	2026-06-18	3,444	—	$0	6,281	SEC↗
Srivastava Sapna	Director	A Award	2026-06-16	2026-06-18	3,444	—	$0	8,590	SEC↗
Wheeler Cameron	Director	A Award	2026-06-16	2026-06-18	3,444	—	$0	8,590	SEC↗
DEERFIELD MANAGEMENT COMPANY,	Director, 10% Owner	A Award	2026-06-16	2026-06-18	3,444	—	$0	3,444	SEC↗
Noci Darlene	Chief Development Officer	M Exercise deriv	2026-06-09	2026-06-11	685	—	$0	6,091	SEC↗
Noci Darlene	Chief Development Officer	M Exercise deriv	2026-06-09	2026-06-11	9,315	—	$0	24,258	SEC↗
Noci Darlene	Chief Development Officer	M Exercise deriv	2026-06-09	2026-06-11	10,000	—	$0	216	SEC↗
Noci Darlene	Chief Development Officer	M Exercise	2026-06-09	2026-06-11	10,000	$1.08	$10.8K	68,117	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-06-09	2026-06-11	20,000	$122.81	$2.46M	58,117	SEC↗
Noci Darlene	Chief Development Officer	M Exercise	2026-06-09	2026-06-11	9,315	$18.93	$176.3K	78,117	SEC↗
Noci Darlene	Chief Development Officer	M Exercise	2026-06-09	2026-06-11	685	$6.89	$4.7K	68,802	SEC↗
Porter James Richard	President and CEO	M Exercise deriv	2026-06-08	2026-06-10	30,000	—	$0	148,686	SEC↗
Porter James Richard	President and CEO	S Sale	2026-06-08	2026-06-10	3,036	$89.63	$272.1K	324,879	SEC↗
Porter James Richard	President and CEO	S Sale	2026-06-08	2026-06-10	14,469	$88.79	$1.28M	327,915	SEC↗
Porter James Richard	President and CEO	S Sale	2026-06-08	2026-06-10	12,495	$87.97	$1.10M	342,384	SEC↗
Porter James Richard	President and CEO	M Exercise	2026-06-08	2026-06-10	30,000	$18.93	$567.9K	354,879	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise deriv	2026-06-01	2026-06-03	11,430	—	$0	13,400	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-06-01	2026-06-03	279	$101.79	$28.4K	85,733	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-06-01	2026-06-03	2,588	$100.65	$260.5K	86,012	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-06-01	2026-06-03	3,133	$99.86	$312.9K	88,600	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-06-01	2026-06-03	200	$103.84	$20.8K	85,533	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-06-01	2026-06-03	2,170	$95.99	$208.3K	93,833	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-06-01	2026-06-03	960	$94.87	$91.1K	96,003	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-06-01	2026-06-03	1,200	$98.57	$118.3K	91,733	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise	2026-06-01	2026-06-03	11,430	$6.89	$78.8K	96,963	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-06-01	2026-06-03	900	$97.68	$87.9K	92,933	SEC↗
Miller Deborah Ann	Chief Legal Officer	M Exercise deriv	2026-05-28	2026-06-01	5,500	—	$0	72,608	SEC↗
Noci Darlene	Chief Development Officer	M Exercise deriv	2026-05-28	2026-06-01	5,500	—	$0	86,829	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-05-28	2026-06-01	1,401	$106.32	$149.0K	63,733	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-05-28	2026-06-01	1,530	$107.45	$164.4K	62,203	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-05-28	2026-06-01	900	$108.14	$97.3K	61,303	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-05-28	2026-06-01	1,669	$109.30	$182.4K	59,634	SEC↗
Miller Deborah Ann	Chief Legal Officer	M Exercise	2026-05-28	2026-06-01	5,500	$6.89	$37.9K	65,134	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-05-28	2026-06-01	100	$109.76	$11.0K	58,117	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-05-28	2026-06-01	1,500	$109.30	$163.9K	58,217	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-05-28	2026-06-01	1,178	$108.01	$127.2K	59,717	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-05-28	2026-06-01	1,422	$107.33	$152.6K	60,895	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-05-28	2026-06-01	1,300	$106.26	$138.1K	62,317	SEC↗
Noci Darlene	Chief Development Officer	M Exercise	2026-05-28	2026-06-01	5,500	$27.85	$153.2K	63,617	SEC↗
Porter James Richard	President and CEO	M Exercise deriv	2026-05-04	2026-05-06	30,000	—	$0	178,686	SEC↗
Porter James Richard	President and CEO	M Exercise	2026-05-04	2026-05-06	30,000	$18.93	$567.9K	354,879	SEC↗
Porter James Richard	President and CEO	S Sale	2026-05-04	2026-05-06	1,699	$98.54	$167.4K	353,180	SEC↗
Porter James Richard	President and CEO	S Sale	2026-05-04	2026-05-06	1,408	$99.77	$140.5K	351,772	SEC↗
Porter James Richard	President and CEO	S Sale	2026-05-04	2026-05-06	7,429	$101.48	$753.9K	344,343	SEC↗
Porter James Richard	President and CEO	S Sale	2026-05-04	2026-05-06	17,353	$102.10	$1.77M	326,990	SEC↗
Porter James Richard	President and CEO	S Sale	2026-05-04	2026-05-06	2,111	$102.88	$217.2K	324,879	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise deriv	2026-05-01	2026-05-05	4,271	—	$0	24,830	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise deriv	2026-05-01	2026-05-05	7,159	—	$0	131,637	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-05-01	2026-05-05	3,872	$98.42	$381.1K	93,091	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise	2026-05-01	2026-05-05	7,159	$1.08	$7.7K	92,692	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-05-01	2026-05-05	7,434	$99.29	$738.1K	85,657	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-05-01	2026-05-05	124	$99.97	$12.4K	85,533	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise	2026-05-01	2026-05-05	4,271	$6.89	$29.4K	96,963	SEC↗
Miller Deborah Ann	Chief Legal Officer	M Exercise deriv	2026-04-30	2026-05-01	5,500	—	$0	78,108	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-04-30	2026-05-01	1,082	$99.57	$107.7K	59,634	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-04-30	2026-05-01	4,418	$99.13	$438.0K	60,716	SEC↗
Miller Deborah Ann	Chief Legal Officer	M Exercise	2026-04-30	2026-05-01	5,500	$6.89	$37.9K	65,134	SEC↗
Noci Darlene	Chief Development Officer	M Exercise deriv	2026-04-29	2026-05-01	5,500	—	$0	92,329	SEC↗
Noci Darlene	Chief Development Officer	M Exercise	2026-04-29	2026-05-01	5,500	$27.85	$153.2K	63,617	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-04-29	2026-05-01	4,500	$99.35	$447.1K	59,117	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-04-29	2026-05-01	700	$100.14	$70.1K	58,417	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-04-29	2026-05-01	300	$101.17	$30.4K	58,117	SEC↗
Pelish Henry E.	Chief Scientific Officer	M Exercise deriv	2026-04-09	2026-04-13	3,093	—	$0	8,309	SEC↗
Pelish Henry E.	Chief Scientific Officer	S Sale	2026-04-09	2026-04-13	900	$105.00	$94.5K	65,604	SEC↗
Pelish Henry E.	Chief Scientific Officer	S Sale	2026-04-09	2026-04-13	2,193	$104.27	$228.7K	66,504	SEC↗
Pelish Henry E.	Chief Scientific Officer	M Exercise	2026-04-09	2026-04-13	3,093	$27.85	$86.1K	68,697	SEC↗
Porter James Richard	President and CEO	M Exercise deriv	2026-04-06	2026-04-08	16,286	—	$0	131,494	SEC↗
Porter James Richard	President and CEO	M Exercise deriv	2026-04-06	2026-04-08	13,714	—	$0	208,686	SEC↗
Porter James Richard	President and CEO	M Exercise	2026-04-06	2026-04-08	13,714	$18.93	$259.6K	338,593	SEC↗
Porter James Richard	President and CEO	M Exercise	2026-04-06	2026-04-08	16,286	$27.85	$453.6K	354,879	SEC↗
Porter James Richard	President and CEO	S Sale	2026-04-06	2026-04-08	11,354	$103.21	$1.17M	343,525	SEC↗
Porter James Richard	President and CEO	S Sale	2026-04-06	2026-04-08	12,425	$103.78	$1.29M	331,100	SEC↗
Porter James Richard	President and CEO	S Sale	2026-04-06	2026-04-08	6,121	$104.78	$641.4K	324,979	SEC↗
Porter James Richard	President and CEO	S Sale	2026-04-06	2026-04-08	100	$105.60	$10.6K	324,879	SEC↗
Lane Benjamin	See Remarks	A Award deriv	2026-04-01	2026-04-02	19,000	—	$0	19,000	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise deriv	2026-04-01	2026-04-03	11,430	—	$0	138,796	SEC↗
Lane Benjamin	See Remarks	A Award	2026-04-01	2026-04-02	9,500	—	$0	50,368	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-04-01	2026-04-03	3,544	$104.39	$370.0K	93,419	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-04-01	2026-04-03	5,417	$105.30	$570.4K	88,002	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise	2026-04-01	2026-04-03	11,430	$1.08	$12.3K	96,963	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-04-01	2026-04-03	2,469	$106.18	$262.2K	85,533	SEC↗
Noci Darlene	Chief Development Officer	M Exercise deriv	2026-03-30	2026-04-01	5,500	—	$0	97,829	SEC↗
Noci Darlene	Chief Development Officer	M Exercise	2026-03-30	2026-04-01	5,500	$27.85	$153.2K	63,617	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-03-30	2026-04-01	2,532	$97.43	$246.7K	61,085	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-03-30	2026-04-01	2,968	$98.13	$291.2K	58,117	SEC↗
Miller Deborah Ann	Chief Legal Officer	M Exercise deriv	2026-03-26	2026-03-30	5,500	—	$0	83,608	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-03-26	2026-03-30	2,803	$99.46	$278.8K	59,634	SEC↗
Miller Deborah Ann	Chief Legal Officer	M Exercise	2026-03-26	2026-03-30	5,500	$6.89	$37.9K	65,134	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-03-26	2026-03-30	940	$97.50	$91.7K	64,194	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-03-26	2026-03-30	1,757	$98.21	$172.6K	62,437	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-03-25	2026-03-26	13,700	$100.16	$1.37M	85,533	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise deriv	2026-03-24	2026-03-26	11,430	—	$0	150,226	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-03-24	2026-03-26	1,160	$96.50	$111.9K	99,233	SEC↗
Balcom Alexandra	Chief Financial Officer	M Exercise	2026-03-24	2026-03-26	11,430	$1.08	$12.3K	110,663	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-03-24	2026-03-26	2,599	$95.03	$247.0K	108,064	SEC↗
Balcom Alexandra	Chief Financial Officer	S Sale	2026-03-24	2026-03-26	7,671	$95.88	$735.5K	100,393	SEC↗
Pelish Henry E.	Chief Scientific Officer	S Sale	2026-03-13	2026-03-16	2,597	$98.83	$256.7K	67,307	SEC↗
Pelish Henry E.	Chief Scientific Officer	S Sale	2026-03-13	2026-03-16	804	$97.89	$78.7K	69,904	SEC↗
Pelish Henry E.	Chief Scientific Officer	S Sale	2026-03-13	2026-03-16	1,703	$99.71	$169.8K	65,604	SEC↗
Pelish Henry E.	Chief Scientific Officer	M Exercise deriv	2026-03-12	2026-03-16	2,985	—	$0	21,073	SEC↗
Pelish Henry E.	Chief Scientific Officer	M Exercise deriv	2026-03-12	2026-03-16	8,456	—	$0	2,113	SEC↗
Pelish Henry E.	Chief Scientific Officer	M Exercise deriv	2026-03-12	2026-03-16	1,754	—	$0	11,402	SEC↗
Pelish Henry E.	Chief Scientific Officer	M Exercise deriv	2026-03-12	2026-03-16	4,125	—	$0	9,900	SEC↗
Pelish Henry E.	Chief Scientific Officer	S Sale	2026-03-12	2026-03-16	306	$99.12	$30.3K	70,708	SEC↗
Pelish Henry E.	Chief Scientific Officer	S Sale	2026-03-12	2026-03-16	5,505	$98.44	$541.9K	71,014	SEC↗
Pelish Henry E.	Chief Scientific Officer	S Sale	2026-03-12	2026-03-16	24,189	$97.79	$2.37M	76,519	SEC↗
Pelish Henry E.	Chief Scientific Officer	M Exercise	2026-03-12	2026-03-16	4,125	$29.33	$121.0K	97,723	SEC↗
Pelish Henry E.	Chief Scientific Officer	M Exercise	2026-03-12	2026-03-16	1,754	$27.85	$48.8K	93,598	SEC↗
Pelish Henry E.	Chief Scientific Officer	M Exercise	2026-03-12	2026-03-16	8,456	$18.93	$160.1K	91,844	SEC↗
Pelish Henry E.	Chief Scientific Officer	M Exercise	2026-03-12	2026-03-16	2,985	$72.35	$216.0K	100,708	SEC↗
Porter James Richard	President and CEO	M Exercise deriv	2026-03-06	2026-03-10	30,000	—	$0	147,780	SEC↗
Porter James Richard	President and CEO	S Sale	2026-03-06	2026-03-10	16,015	$99.29	$1.59M	325,279	SEC↗
Porter James Richard	President and CEO	S Sale	2026-03-06	2026-03-10	13,585	$98.59	$1.34M	341,294	SEC↗
Porter James Richard	President and CEO	M Exercise	2026-03-06	2026-03-10	30,000	$27.85	$835.5K	354,879	SEC↗
Porter James Richard	President and CEO	S Sale	2026-03-06	2026-03-10	400	$100.19	$40.1K	324,879	SEC↗
Miller Deborah Ann	Chief Legal Officer	M Exercise deriv	2026-02-26	2026-03-02	5,500	—	$0	89,108	SEC↗
Noci Darlene	Chief Development Officer	M Exercise deriv	2026-02-26	2026-03-02	5,500	—	$0	103,329	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-02-26	2026-03-02	2,602	$103.41	$269.1K	59,834	SEC↗
Miller Deborah Ann	Chief Legal Officer	M Exercise	2026-02-26	2026-03-02	5,500	$6.89	$37.9K	65,134	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-02-26	2026-03-02	2,698	$102.64	$276.9K	62,436	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-02-26	2026-03-02	200	$103.96	$20.8K	59,634	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-02-26	2026-03-02	3,000	$102.64	$307.9K	60,617	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-02-26	2026-03-02	2,300	$103.44	$237.9K	58,317	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-02-26	2026-03-02	200	$104.25	$20.9K	58,117	SEC↗
Noci Darlene	Chief Development Officer	M Exercise	2026-02-26	2026-03-02	5,500	$27.85	$153.2K	63,617	SEC↗
Noci Darlene	Chief Development Officer	M Exercise deriv	2026-01-29	2026-02-02	5,500	—	$0	108,829	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-01-29	2026-02-02	189	$100.95	$19.1K	63,428	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-01-29	2026-02-02	3,429	$101.80	$349.1K	59,999	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-01-29	2026-02-02	1,819	$102.67	$186.8K	58,180	SEC↗
Noci Darlene	Chief Development Officer	S Sale	2026-01-29	2026-02-02	63	$103.39	$6.5K	58,117	SEC↗
Noci Darlene	Chief Development Officer	M Exercise	2026-01-29	2026-02-02	5,500	$27.85	$153.2K	63,617	SEC↗
Miller Deborah Ann	Chief Legal Officer	M Exercise deriv	2026-01-22	2026-01-23	14,300	—	$0	75,154	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-01-22	2026-01-23	14,300	$110.16	$1.58M	59,634	SEC↗
Miller Deborah Ann	Chief Legal Officer	M Exercise	2026-01-22	2026-01-23	14,300	$27.85	$398.3K	73,934	SEC↗
Miller Deborah Ann	Chief Legal Officer	M Exercise deriv	2026-01-21	2026-01-23	700	—	$0	89,454	SEC↗
Miller Deborah Ann	Chief Legal Officer	M Exercise	2026-01-21	2026-01-23	700	$27.85	$19.5K	60,334	SEC↗
Miller Deborah Ann	Chief Legal Officer	S Sale	2026-01-21	2026-01-23	700	$109.84	$76.9K	59,634	SEC↗
Porter James Richard	President and CEO	A Award deriv	2026-01-07	2026-01-07	46,250	—	$0	46,250	SEC↗
Balcom Alexandra	Chief Financial Officer	A Award deriv	2026-01-07	2026-01-07	17,500	—	$0	17,500	SEC↗
Turner Christopher Durant	Chief Medical Officer	A Award deriv	2026-01-07	2026-01-07	17,500	—	$0	17,500	SEC↗
Miller Deborah Ann	Chief Legal Officer	A Award deriv	2026-01-07	2026-01-07	17,500	—	$0	17,500	SEC↗
Noci Darlene	Chief Development Officer	A Award deriv	2026-01-07	2026-01-07	17,500	—	$0	17,500	SEC↗
Pelish Henry E.	Chief Scientific Officer	A Award deriv	2026-01-07	2026-01-07	17,500	—	$0	17,500	SEC↗
Porter James Richard	President and CEO	A Award	2026-01-07	2026-01-07	46,250	—	$0	324,879	SEC↗