OCRX

Ocera Therapeutics, Inc.CIK 1274644 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

—

0 trades · 0 insiders

Open-mkt sales · 90d

—

0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for OCRX PRO

XXXX	$█.██M	██	+██%
XXXX	$█.██M	██	+██%
XXXX	$█.██M	██	+██%
XXXX	$█.██M	██	+██%
XXXX	$█.██M	██	+██%

AI insights for OCRX

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

Upgrade to Pro · $99/year Already Pro? Log in

Daily buy vs sell · 90 days

No data yet.

Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Bukofzer Stan	Chief Medical Officer	9	$6.6K	$0	2017-12-11
Byrnes Michael	VP, Finance & Treasurer	17	$29.7K	$0	2017-12-11
Grais Linda S	President and CEO	25	$240.3K	$0	2017-12-11
Kjellson Nina S	Director	19	$2.60M	$0	2017-12-11
Dere Willard H	Director	4	$0	$0	2017-12-11
WEBER ECKARD	Director	21	$0	$0	2017-12-11
James Steven P	Director	8	$0	$0	2017-12-11
WIERENGA WENDALL	Director	12	$18.6K	$0	2017-12-11
VANLENT ANNE	Director	12	$0	$0	2017-12-11
DOVEY BRIAN H	10% Owner	9	$16.01M	$0	2017-12-11
BLAIR JAMES C	10% Owner	8	$16.01M	$0	2017-12-11
DOMAIN ASSOCIATES	10% Owner	1	$0	$0	2017-12-11
TREU JESSE I	10% Owner	7	$16.01M	$0	2017-12-11
POWELL MICHAEL	Director	40	$2.36M	$14.9K	2016-10-31
Aggarwal Gaurav	Chief Business Officer	7	$48.6K	$0	2016-01-15
Patni Rajiv	Chief Development Officer	4	$20.0K	$0	2015-05-07
TETLOW SHARON	Acting CFO & Treasurer	1	$17.5K	$0	2014-07-11
Castaigne Jean-Paul	Director	2	$0	$0	2014-06-11
Ekman Lars	Director	4	$0	$0	2014-06-11
Sofinnova Management VI, L.L.C.	10% Owner	3	$0	$0	2014-03-18
HILLEMAN JERYL L	CFO and Secretary	1	$0	$0	2013-09-03
Shah Pratik	Director	1	$0	$0	2013-08-30
ROUSSEAU FRANCK	Chief Medical & DEV Officer	1	$0	$0	2013-08-13
McGowan Dana S.	CFO and Secretary	8	$0	$0	2013-07-15
Zisson Alex	Other	3	$0	$0	2013-07-15
TMP Associates II LP	10% Owner	9	$0	$0	2013-07-15
Halak Brian K	10% Owner	5	$14.01M	$0	2013-07-15
Thomas, McNerney & Partners, LLC	10% Owner	9	$0	$0	2013-07-15
Domain Partners VI, L.P.	10% Owner	2	$4.00M	$0	2013-07-15
SOFINNOVA VENTURE PARTNERS VI L P	10% Owner	3	$2.36M	$0	2013-07-15
SCHOEMAKER KATHLEEN K	10% Owner	6	$16.01M	$0	2013-07-15
VITULLO NICOLE	10% Owner	6	$16.01M	$0	2013-07-15

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
WIERENGA WENDALL	Director	D To issuer deriv	2017-12-11	2017-12-11	12,500	—	$0	0	SEC↗
WIERENGA WENDALL	Director	D To issuer deriv	2017-12-11	2017-12-11	10,000	—	$0	0	SEC↗
WIERENGA WENDALL	Director	D To issuer deriv	2017-12-11	2017-12-11	10,000	—	$0	0	SEC↗
WIERENGA WENDALL	Director	D To issuer deriv	2017-12-11	2017-12-11	20,000	—	$0	0	SEC↗
WEBER ECKARD	Director	D To issuer deriv	2017-12-11	2017-12-11	2,992	—	$0	0	SEC↗
WEBER ECKARD	Director	D To issuer deriv	2017-12-11	2017-12-11	2,992	—	$0	0	SEC↗
WEBER ECKARD	Director	D To issuer deriv	2017-12-11	2017-12-11	20,000	—	$0	0	SEC↗
WEBER ECKARD	Director	D To issuer deriv	2017-12-11	2017-12-11	10,000	—	$0	0	SEC↗
WEBER ECKARD	Director	D To issuer deriv	2017-12-11	2017-12-11	10,000	—	$0	0	SEC↗
WEBER ECKARD	Director	D To issuer deriv	2017-12-11	2017-12-11	12,500	—	$0	0	SEC↗
VANLENT ANNE	Director	D To issuer deriv	2017-12-11	2017-12-11	10,000	—	$0	0	SEC↗
VANLENT ANNE	Director	D To issuer deriv	2017-12-11	2017-12-11	12,500	—	$0	0	SEC↗
VANLENT ANNE	Director	D To issuer deriv	2017-12-11	2017-12-11	2,652	—	$0	0	SEC↗
VANLENT ANNE	Director	D To issuer deriv	2017-12-11	2017-12-11	2,083	—	$0	0	SEC↗
VANLENT ANNE	Director	D To issuer deriv	2017-12-11	2017-12-11	10,000	—	$0	0	SEC↗
VANLENT ANNE	Director	D To issuer deriv	2017-12-11	2017-12-11	20,000	—	$0	0	SEC↗
Dere Willard H	Director	D To issuer deriv	2017-12-11	2017-12-11	20,000	—	$0	0	SEC↗
Byrnes Michael	CFO and Treasurer	D To issuer deriv	2017-12-11	2017-12-11	123,300	—	$0	0	SEC↗
Byrnes Michael	CFO and Treasurer	D To issuer deriv	2017-12-11	2017-12-11	55,000	—	$0	0	SEC↗
Byrnes Michael	CFO and Treasurer	D To issuer deriv	2017-12-11	2017-12-11	75,000	—	$0	0	SEC↗
Byrnes Michael	CFO and Treasurer	D To issuer deriv	2017-12-11	2017-12-11	102,300	—	$0	0	SEC↗
Byrnes Michael	CFO and Treasurer	D To issuer deriv	2017-12-11	2017-12-11	70,000	—	$0	0	SEC↗
James Steven P	Director	D To issuer deriv	2017-12-11	2017-12-11	10,000	—	$0	0	SEC↗
James Steven P	Director	D To issuer deriv	2017-12-11	2017-12-11	12,500	—	$0	0	SEC↗
James Steven P	Director	D To issuer deriv	2017-12-11	2017-12-11	20,000	—	$0	0	SEC↗
Bukofzer Stan	Chief Medical Officer	D To issuer deriv	2017-12-11	2017-12-11	300,000	—	$0	0	SEC↗
Bukofzer Stan	Chief Medical Officer	D To issuer deriv	2017-12-11	2017-12-11	208,350	—	$0	0	SEC↗
Kjellson Nina S	Director	D To issuer deriv	2017-12-11	2017-12-11	12,500	—	$0	0	SEC↗
Kjellson Nina S	Director	D To issuer deriv	2017-12-11	2017-12-11	10,000	—	$0	0	SEC↗
Kjellson Nina S	Director	D To issuer deriv	2017-12-11	2017-12-11	10,000	—	$0	0	SEC↗
Kjellson Nina S	Director	D To issuer deriv	2017-12-11	2017-12-11	20,000	—	$0	0	SEC↗
Grais Linda S	President and CEO	D To issuer deriv	2017-12-11	2017-12-11	30,827	—	$0	0	SEC↗
Grais Linda S	President and CEO	D To issuer deriv	2017-12-11	2017-12-11	11,969	—	$0	0	SEC↗
Grais Linda S	President and CEO	D To issuer deriv	2017-12-11	2017-12-11	30,826	—	$0	0	SEC↗
Grais Linda S	President and CEO	D To issuer deriv	2017-12-11	2017-12-11	37,500	—	$0	0	SEC↗
Grais Linda S	President and CEO	D To issuer deriv	2017-12-11	2017-12-11	491,550	—	$0	0	SEC↗
Grais Linda S	President and CEO	D To issuer deriv	2017-12-11	2017-12-11	160,000	—	$0	0	SEC↗
Grais Linda S	President and CEO	D To issuer deriv	2017-12-11	2017-12-11	348,600	—	$0	0	SEC↗
Grais Linda S	President and CEO	D To issuer deriv	2017-12-11	2017-12-11	289,200	—	$0	0	SEC↗
DOVEY BRIAN H	10% Owner	D To issuer deriv	2017-12-11	2017-12-13	20,150	—	$0	0	SEC↗
DOVEY BRIAN H	10% Owner	D To issuer deriv	2017-12-11	2017-12-13	20,150	—	$0	0	SEC↗
WIERENGA WENDALL	Director	D To issuer	2017-12-11	2017-12-11	12,500	$1.52	$19.0K	0	SEC↗
WIERENGA WENDALL	Director	D To issuer	2017-12-11	2017-12-11	5,000	$1.52	$7.6K	0	SEC↗
WEBER ECKARD	Director	D To issuer	2017-12-11	2017-12-11	344,719	$1.52	$524.0K	0	SEC↗
WEBER ECKARD	Director	D To issuer	2017-12-11	2017-12-11	11,969	$1.52	$18.2K	0	SEC↗
WEBER ECKARD	Director	D To issuer	2017-12-11	2017-12-11	12,500	$1.52	$19.0K	0	SEC↗
VANLENT ANNE	Director	D To issuer	2017-12-11	2017-12-11	12,500	$1.52	$19.0K	0	SEC↗
Dere Willard H	Director	D To issuer	2017-12-11	2017-12-11	12,500	$1.52	$19.0K	0	SEC↗
Byrnes Michael	CFO and Treasurer	D To issuer	2017-12-11	2017-12-11	13,000	$1.52	$19.8K	0	SEC↗
Byrnes Michael	CFO and Treasurer	D To issuer	2017-12-11	2017-12-11	150,000	$1.52	$228.0K	0	SEC↗
James Steven P	Director	D To issuer	2017-12-11	2017-12-11	12,500	$1.52	$19.0K	0	SEC↗
Bukofzer Stan	Chief Medical Officer	D To issuer	2017-12-11	2017-12-11	200,000	$1.52	$304.0K	0	SEC↗
Bukofzer Stan	Chief Medical Officer	D To issuer	2017-12-11	2017-12-11	2,500	$1.52	$3.8K	0	SEC↗
Kjellson Nina S	Director	D To issuer	2017-12-11	2017-12-11	12,500	$1.52	$19.0K	0	SEC↗
Grais Linda S	President and CEO	D To issuer	2017-12-11	2017-12-11	70,000	$1.52	$106.4K	0	SEC↗
Grais Linda S	President and CEO	D To issuer	2017-12-11	2017-12-11	230,000	$1.52	$349.6K	0	SEC↗
BLAIR JAMES C	10% Owner	D To issuer	2017-12-11	2017-12-13	988,285	—	$0	0	SEC↗
BLAIR JAMES C	10% Owner	D To issuer	2017-12-11	2017-12-13	7,333	—	$0	0	SEC↗
DOVEY BRIAN H	10% Owner	D To issuer	2017-12-11	2017-12-13	1,857,036	—	$0	0	SEC↗
TREU JESSE I	10% Owner	D To issuer	2017-12-11	2017-12-13	15,731	—	$0	0	SEC↗
DOMAIN ASSOCIATES	10% Owner	D To issuer	2017-12-11	2017-12-13	47,963	—	$0	0	SEC↗
VANLENT ANNE	Director	A Award	2017-06-20	2017-06-22	12,500	—	$0	12,500	SEC↗
Kjellson Nina S	Director	A Award	2017-06-20	2017-06-22	12,500	—	$0	12,500	SEC↗
WEBER ECKARD	Director	A Award	2017-06-20	2017-06-22	12,500	—	$0	12,500	SEC↗
James Steven P	Director	A Award	2017-06-20	2017-06-22	12,500	—	$0	12,500	SEC↗
WIERENGA WENDALL	Director	A Award	2017-06-20	2017-06-22	12,500	—	$0	17,500	SEC↗
Dere Willard H	Director	A Award	2017-06-20	2017-06-22	12,500	—	$0	12,500	SEC↗
Grais Linda S	President and CEO	A Award	2017-03-29	2017-03-30	230,000	—	$0	300,000	SEC↗
Bukofzer Stan	Chief Medical Officer	A Award	2017-03-29	2017-03-30	200,000	—	$0	202,500	SEC↗
Byrnes Michael	CFO and Treasurer	A Award	2017-03-29	2017-03-30	150,000	—	$0	163,000	SEC↗
Byrnes Michael	CFO and Treasurer	P Buy	2017-03-28	2017-03-28	3,000	$1.28	$3.8K	13,000	SEC↗
Bukofzer Stan	Chief Medical Officer	A Award deriv	2016-12-15	2016-12-16	208,350	—	$0	208,350	SEC↗
Byrnes Michael	CFO and Treasurer	A Award deriv	2016-12-15	2016-12-16	102,300	—	$0	102,300	SEC↗
Grais Linda S	President and CEO	A Award deriv	2016-12-15	2016-12-16	289,200	—	$0	289,200	SEC↗
Grais Linda S	President and CEO	P Buy	2016-12-07	2016-12-08	7,000	$2.14	$15.0K	70,000	SEC↗
POWELL MICHAEL	Director	J Other	2016-10-31	2016-12-30	138,686	—	$0	0	SEC↗
POWELL MICHAEL	Director	J Other	2016-10-31	2016-12-30	9,540	—	$0	0	SEC↗
POWELL MICHAEL	Director	J Other	2016-10-31	2016-12-30	14,328	—	$0	14,328	SEC↗
POWELL MICHAEL	Director	J Other	2016-10-31	2016-12-30	699,996	—	$0	0	SEC↗
Dere Willard H	Director	A Award deriv	2016-10-26	2016-10-28	20,000	—	$0	20,000	SEC↗
Bukofzer Stan	Chief Medical Officer	P Buy	2016-10-13	2016-10-17	2,500	$2.64	$6.6K	2,500	SEC↗
POWELL MICHAEL	Director	X Exercise deriv	2016-09-12	2016-12-30	1,820	—	$0	0	SEC↗
POWELL MICHAEL	Director	X Exercise deriv	2016-09-12	2016-12-30	1,820	—	$0	0	SEC↗
POWELL MICHAEL	Director	X Exercise deriv	2016-09-12	2016-12-30	9,187	—	$0	0	SEC↗
POWELL MICHAEL	Director	X Exercise deriv	2016-09-12	2016-12-30	125	—	$0	0	SEC↗
POWELL MICHAEL	Director	X Exercise deriv	2016-09-12	2016-12-30	125	—	$0	0	SEC↗
POWELL MICHAEL	Director	X Exercise deriv	2016-09-12	2016-12-30	9,187	—	$0	0	SEC↗
POWELL MICHAEL	Director	X Exercise	2016-09-12	2016-12-30	18,374	$0.67	$12.3K	705,368	SEC↗
POWELL MICHAEL	Director	X Exercise	2016-09-12	2016-12-30	3,640	$0.67	$2.4K	139,752	SEC↗
POWELL MICHAEL	Director	S Sale	2016-09-12	2016-12-30	74	$2.29	$169	9,540	SEC↗
POWELL MICHAEL	Director	S Sale	2016-09-12	2016-12-30	1,066	$2.29	$2.4K	138,686	SEC↗
POWELL MICHAEL	Director	S Sale	2016-09-12	2016-12-30	5,372	$2.29	$12.3K	699,996	SEC↗
POWELL MICHAEL	Director	X Exercise	2016-09-12	2016-12-30	250	$0.67	$168	9,614	SEC↗
POWELL MICHAEL	Director	M Exercise deriv	2016-07-11	2016-07-13	11,969	—	$0	0	SEC↗
POWELL MICHAEL	Director	M Exercise	2016-07-11	2016-07-13	11,969	$1.26	$15.1K	11,969	SEC↗
WIERENGA WENDALL	Director	A Award deriv	2016-06-14	2016-06-15	12,500	—	$0	12,500	SEC↗
POWELL MICHAEL	Director	A Award deriv	2016-06-14	2016-06-15	12,500	—	$0	12,500	SEC↗
VANLENT ANNE	Director	A Award deriv	2016-06-14	2016-06-15	12,500	—	$0	12,500	SEC↗
WEBER ECKARD	Director	A Award deriv	2016-06-14	2016-06-15	12,500	—	$0	12,500	SEC↗
Kjellson Nina S	Director	A Award deriv	2016-06-14	2016-06-15	12,500	—	$0	12,500	SEC↗
James Steven P	Director	A Award deriv	2016-06-14	2016-06-15	12,500	—	$0	12,500	SEC↗
Grais Linda S	President and CEO	P Buy	2016-03-04	2016-03-07	3,000	$3.19	$9.6K	63,000	SEC↗
Grais Linda S	President and CEO	P Buy	2016-01-22	2016-01-25	10,000	$2.38	$23.8K	60,000	SEC↗
Aggarwal Gaurav	Chief Business Officer	P Buy	2016-01-15	2016-01-19	10,000	$2.15	$21.5K	20,000	SEC↗
Byrnes Michael	CFO and Treasurer	P Buy	2016-01-15	2016-01-19	3,500	$2.07	$7.2K	10,000	SEC↗
Grais Linda S	President and CEO	P Buy	2016-01-15	2016-01-19	10,000	$2.08	$20.8K	50,000	SEC↗
Grais Linda S	President and CEO	A Award deriv	2016-01-06	2016-01-07	116,200	—	$0	116,200	SEC↗
Grais Linda S	President and CEO	A Award deriv	2016-01-06	2016-01-07	348,600	—	$0	348,600	SEC↗
Aggarwal Gaurav	Chief Business Officer	A Award deriv	2016-01-06	2016-01-07	147,975	—	$0	147,975	SEC↗
Aggarwal Gaurav	Chief Business Officer	A Award deriv	2016-01-06	2016-01-07	49,325	—	$0	49,325	SEC↗
Byrnes Michael	CFO and Treasurer	A Award deriv	2016-01-06	2016-01-07	41,100	—	$0	41,100	SEC↗
Byrnes Michael	CFO and Treasurer	A Award deriv	2016-01-06	2016-01-07	123,300	—	$0	123,300	SEC↗
Bukofzer Stan	Chief Medical Officer	A Award deriv	2016-01-05	2016-01-07	300,000	—	$0	300,000	SEC↗
Bukofzer Stan	Chief Medical Officer	A Award deriv	2016-01-05	2016-01-07	100,000	—	$0	100,000	SEC↗
WEBER ECKARD	Director	M Exercise deriv	2016-01-04	2016-01-06	11,969	—	$0	0	SEC↗
WEBER ECKARD	Director	M Exercise	2016-01-04	2016-01-06	11,969	$0.92	$11.0K	356,688	SEC↗
WEBER ECKARD	Director	G Gift	2016-01-04	2016-01-06	11,969	—	$0	344,719	SEC↗
WIERENGA WENDALL	Director	P Buy	2015-06-23	2015-06-24	5,000	$3.71	$18.6K	5,000	SEC↗
WIERENGA WENDALL	Director	A Award deriv	2015-06-18	2015-06-22	10,000	—	$0	10,000	SEC↗
POWELL MICHAEL	Director	A Award deriv	2015-06-18	2015-06-22	10,000	—	$0	10,000	SEC↗
Kjellson Nina S	Director	A Award deriv	2015-06-18	2015-06-22	10,000	—	$0	10,000	SEC↗
James Steven P	Director	A Award deriv	2015-06-18	2015-06-22	10,000	—	$0	10,000	SEC↗
VANLENT ANNE	Director	A Award deriv	2015-06-18	2015-06-22	10,000	—	$0	10,000	SEC↗
WEBER ECKARD	Director	A Award deriv	2015-06-18	2015-06-22	10,000	—	$0	10,000	SEC↗
Aggarwal Gaurav	Chief Business Officer	A Award deriv	2015-06-18	2015-06-22	75,000	—	$0	75,000	SEC↗
Byrnes Michael	CFO and Treasurer	A Award deriv	2015-06-18	2015-06-22	75,000	—	$0	75,000	SEC↗
Grais Linda S	President and CEO	A Award deriv	2015-06-18	2015-06-22	160,000	—	$0	160,000	SEC↗
Patni Rajiv	Chief Development Officer	P Buy	2015-05-07	2015-05-07	5,050	$3.97	$20.0K	5,050	SEC↗
Aggarwal Gaurav	Chief Business Officer	P Buy	2015-05-06	2015-05-06	7,500	$3.62	$27.1K	10,000	SEC↗
Byrnes Michael	CFO and Treasurer	P Buy	2015-05-06	2015-05-06	2,500	$3.61	$9.0K	6,500	SEC↗
Grais Linda S	President and CEO	P Buy	2015-05-06	2015-05-06	30,000	$3.73	$111.9K	40,000	SEC↗
Byrnes Michael	CFO and Treasurer	A Award deriv	2014-12-02	2014-12-04	70,000	—	$0	70,000	SEC↗
Byrnes Michael	VP, Finance & Treasurer	P Buy	2014-10-01	2014-10-02	2,000	$4.81	$9.6K	4,000	SEC↗
James Steven P	Director	A Award deriv	2014-09-17	2014-09-18	20,000	—	$0	20,000	SEC↗
Patni Rajiv	Chief Development Officer	A Award deriv	2014-09-02	2014-09-02	250,000	—	$0	250,000	SEC↗
Patni Rajiv	Chief Development Officer	A Award deriv	2014-09-02	2014-09-02	20,000	—	$0	20,000	SEC↗
Patni Rajiv	Chief Development Officer	A Award deriv	2014-09-02	2014-09-02	20,000	—	$0	20,000	SEC↗
Grais Linda S	President and CEO	P Buy	2014-07-11	2014-07-15	10,000	$5.93	$59.3K	10,000	SEC↗
TETLOW SHARON	Acting CFO & Treasurer	P Buy	2014-07-11	2014-07-15	3,000	$5.83	$17.5K	3,000	SEC↗
Ekman Lars	Director	A Award deriv	2014-06-11	2014-06-13	10,000	—	$0	10,000	SEC↗
VANLENT ANNE	Director	A Award deriv	2014-06-11	2014-06-13	10,000	—	$0	10,000	SEC↗
POWELL MICHAEL	Director	A Award deriv	2014-06-11	2014-06-13	10,000	—	$0	10,000	SEC↗
WIERENGA WENDALL	Director	A Award deriv	2014-06-11	2014-06-13	10,000	—	$0	10,000	SEC↗
Aggarwal Gaurav	Chief Business Officer	A Award deriv	2014-06-11	2014-06-13	25,000	—	$0	25,000	SEC↗
Castaigne Jean-Paul	Director	A Award deriv	2014-06-11	2014-06-13	10,000	—	$0	10,000	SEC↗
Kjellson Nina S	Director	A Award deriv	2014-06-11	2014-06-13	10,000	—	$0	10,000	SEC↗
Grais Linda S	President & CEO	A Award deriv	2014-06-11	2014-06-13	75,000	—	$0	75,000	SEC↗
WEBER ECKARD	Director	A Award deriv	2014-06-11	2014-06-20	10,000	—	$0	10,000	SEC↗
Aggarwal Gaurav	Chief Business Officer	A Award deriv	2014-04-30	2014-05-02	175,000	—	$0	175,000	SEC↗
Sofinnova Management VI, L.L.C	10% Owner	J Other	2014-03-18	2014-03-20	338,370	—	$0	686,994	SEC↗
Sofinnova Management VI, L.L.C	10% Owner	J Other	2014-03-18	2014-03-20	4,612	—	$0	9,364	SEC↗
Sofinnova Management VI, L.L.C	10% Owner	J Other	2014-03-18	2014-03-20	67,040	—	$0	136,112	SEC↗
POWELL MICHAEL	Director	J Other	2014-03-18	2014-03-20	338,370	—	$0	686,994	SEC↗
POWELL MICHAEL	Director	J Other	2014-03-18	2014-03-20	67,040	—	$0	136,112	SEC↗
POWELL MICHAEL	Director	J Other	2014-03-18	2014-03-20	4,612	—	$0	9,364	SEC↗
WIERENGA WENDALL	Director	A Award deriv	2013-12-19	2013-12-23	20,000	—	$0	20,000	SEC↗
Kjellson Nina S	Director	P Buy deriv	2013-11-08	2013-11-12	84,448	—	$0	84,448	SEC↗
Kjellson Nina S	Director	P Buy	2013-11-08	2013-11-12	422,238	—	$0	1,248,064	SEC↗
HILLEMAN JERYL L	CFO and Secretary	A Award deriv	2013-09-03	2013-12-23	200,000	—	$0	200,000	SEC↗
WEBER ECKARD	Director	A Award deriv	2013-08-30	2013-12-23	20,000	—	$0	20,000	SEC↗
Castaigne Jean-Paul	Director	A Award deriv	2013-08-30	2013-12-23	20,000	—	$0	20,000	SEC↗
Ekman Lars	Director	A Award deriv	2013-08-30	2013-12-23	20,000	—	$0	20,000	SEC↗
Kjellson Nina S	Director	A Award deriv	2013-08-30	2013-12-23	20,000	—	$0	20,000	SEC↗
POWELL MICHAEL	Director	A Award deriv	2013-08-30	2013-12-23	20,000	—	$0	20,000	SEC↗
Shah Pratik	Director	A Award deriv	2013-08-30	2013-12-23	20,000	—	$0	20,000	SEC↗
VANLENT ANNE	Director	A Award deriv	2013-08-30	2013-12-23	20,000	—	$0	20,000	SEC↗
Grais Linda S	President and CEO	A Award deriv	2013-08-13	2013-12-23	491,550	—	$0	491,550	SEC↗
ROUSSEAU FRANCK	Chief Medical & DEV Officer	A Award deriv	2013-08-13	2013-12-23	226,000	—	$0	226,000	SEC↗
McGowan Dana S.	CFO and Secretary	A Award deriv	2013-07-15	2013-07-16	17,954	—	$0	17,954	SEC↗
McGowan Dana S.	CFO and Secretary	A Award deriv	2013-07-15	2013-07-16	8,683	—	$0	8,683	SEC↗
McGowan Dana S.	CFO and Secretary	A Award deriv	2013-07-15	2013-07-16	4,818	—	$0	4,818	SEC↗
McGowan Dana S.	CFO and Secretary	A Award deriv	2013-07-15	2013-07-16	14,680	—	$0	14,680	SEC↗
McGowan Dana S.	CFO and Secretary	A Award deriv	2013-07-15	2013-07-16	5,984	—	$0	5,984	SEC↗
McGowan Dana S.	CFO and Secretary	A Award deriv	2013-07-15	2013-07-16	5,330	—	$0	5,330	SEC↗
McGowan Dana S.	CFO and Secretary	A Award deriv	2013-07-15	2013-07-16	5,984	—	$0	5,984	SEC↗
McGowan Dana S.	CFO and Secretary	A Award deriv	2013-07-15	2013-07-16	4,488	—	$0	4,488	SEC↗
WEBER ECKARD	Director	A Award deriv	2013-07-15	2013-07-16	2,992	—	$0	2,992	SEC↗
WEBER ECKARD	Director	A Award deriv	2013-07-15	2013-07-16	2,992	—	$0	2,992	SEC↗
WEBER ECKARD	Director	A Award deriv	2013-07-15	2013-07-16	11,969	—	$0	11,969	SEC↗
Kjellson Nina S	Director	A Award deriv	2013-07-15	2013-07-17	2,992	—	$0	2,992	SEC↗
Kjellson Nina S	Director	A Award deriv	2013-07-15	2013-07-17	2,992	—	$0	2,992	SEC↗
Kjellson Nina S	Director	A Award deriv	2013-07-15	2013-07-17	11,969	—	$0	11,969	SEC↗
Kjellson Nina S	Director	A Award deriv	2013-07-15	2013-07-17	5,157	—	$0	5,157	SEC↗
Kjellson Nina S	Director	A Award deriv	2013-07-15	2013-07-17	5,157	—	$0	5,157	SEC↗
Grais Linda S	President and CEO	A Award deriv	2013-07-15	2013-07-17	11,969	—	$0	11,969	SEC↗
Grais Linda S	President and CEO	A Award deriv	2013-07-15	2013-07-17	61,653	—	$0	61,653	SEC↗
POWELL MICHAEL	Director	A Award deriv	2013-07-15	2013-07-17	125	—	$0	125	SEC↗
POWELL MICHAEL	Director	A Award deriv	2013-07-15	2013-07-17	125	—	$0	125	SEC↗
POWELL MICHAEL	Director	A Award deriv	2013-07-15	2013-07-17	1,820	—	$0	1,820	SEC↗
POWELL MICHAEL	Director	A Award deriv	2013-07-15	2013-07-17	1,820	—	$0	1,820	SEC↗
POWELL MICHAEL	Director	A Award deriv	2013-07-15	2013-07-17	9,187	—	$0	9,187	SEC↗
POWELL MICHAEL	Director	A Award deriv	2013-07-15	2013-07-17	9,187	—	$0	9,187	SEC↗
POWELL MICHAEL	Director	A Award deriv	2013-07-15	2013-07-17	2,992	—	$0	2,992	SEC↗
POWELL MICHAEL	Director	A Award deriv	2013-07-15	2013-07-17	2,992	—	$0	2,992	SEC↗
POWELL MICHAEL	Director	A Award deriv	2013-07-15	2013-07-17	11,969	—	$0	11,969	SEC↗
Ekman Lars	Director	A Award deriv	2013-07-15	2013-07-17	11,969	—	$0	11,969	SEC↗
Ekman Lars	Director	A Award deriv	2013-07-15	2013-07-17	2,992	—	$0	2,992	SEC↗
VITULLO NICOLE	10% Owner	P Buy	2013-07-15	2013-07-16	988,285	$6.03	$5.96M	988,285	SEC↗
VITULLO NICOLE	10% Owner	P Buy	2013-07-15	2013-07-16	7,333	$6.03	$44.2K	7,333	SEC↗
VITULLO NICOLE	10% Owner	P Buy	2013-07-15	2013-07-16	331,873	$6.03	$2.00M	1,897,336	SEC↗
TREU JESSE I	10% Owner	P Buy	2013-07-15	2013-07-16	7,333	$6.03	$44.2K	7,333	SEC↗
TREU JESSE I	10% Owner	P Buy	2013-07-15	2013-07-16	988,285	$6.03	$5.96M	988,285	SEC↗
TREU JESSE I	10% Owner	P Buy	2013-07-15	2013-07-16	331,873	$6.03	$2.00M	1,897,336	SEC↗
SCHOEMAKER KATHLEEN K	10% Owner	P Buy	2013-07-15	2013-07-16	331,873	$6.03	$2.00M	1,897,336	SEC↗
SCHOEMAKER KATHLEEN K	10% Owner	P Buy	2013-07-15	2013-07-16	7,333	$6.03	$44.2K	7,333	SEC↗
SCHOEMAKER KATHLEEN K	10% Owner	P Buy	2013-07-15	2013-07-16	988,285	$6.03	$5.96M	988,285	SEC↗
BLAIR JAMES C	10% Owner	P Buy	2013-07-15	2013-07-16	331,873	$6.03	$2.00M	1,897,336	SEC↗
BLAIR JAMES C	10% Owner	P Buy	2013-07-15	2013-07-16	7,333	$6.03	$44.2K	7,333	SEC↗
BLAIR JAMES C	10% Owner	P Buy	2013-07-15	2013-07-16	988,285	$6.03	$5.96M	988,285	SEC↗
Halak Brian K	10% Owner	P Buy	2013-07-15	2013-07-16	331,873	$6.03	$2.00M	1,897,336	SEC↗
Halak Brian K	10% Owner	P Buy	2013-07-15	2013-07-16	7,333	$6.03	$44.2K	7,333	SEC↗
Halak Brian K	10% Owner	P Buy	2013-07-15	2013-07-16	988,285	$6.03	$5.96M	988,285	SEC↗
DOVEY BRIAN H	10% Owner	P Buy	2013-07-15	2013-07-16	988,285	$6.03	$5.96M	988,285	SEC↗
DOVEY BRIAN H	10% Owner	P Buy	2013-07-15	2013-07-16	7,333	$6.03	$44.2K	7,333	SEC↗
DOVEY BRIAN H	10% Owner	P Buy	2013-07-15	2013-07-16	331,873	$6.03	$2.00M	1,897,336	SEC↗
Domain Partners VI, L.P.	10% Owner	P Buy	2013-07-15	2013-07-16	331,873	$6.03	$2.00M	1,897,336	SEC↗
WEBER ECKARD	Director	A Award	2013-07-15	2013-07-16	344,719	—	$0	344,719	SEC↗
Kjellson Nina S	Director	P Buy	2013-07-15	2013-07-17	431,435	$6.03	$2.60M	825,826	SEC↗
Kjellson Nina S	Director	A Award	2013-07-15	2013-07-17	394,391	—	$0	394,391	SEC↗
SOFINNOVA VENTURE PARTNERS VI	10% Owner	P Buy	2013-07-15	2013-07-17	322,809	$6.03	$1.95M	1,025,364	SEC↗
SOFINNOVA VENTURE PARTNERS VI	10% Owner	P Buy	2013-07-15	2013-07-17	63,957	$6.03	$385.7K	203,152	SEC↗
SOFINNOVA VENTURE PARTNERS VI	10% Owner	P Buy	2013-07-15	2013-07-17	4,400	$6.03	$26.5K	13,976	SEC↗
POWELL MICHAEL	Director	J Other	2013-07-15	2013-07-17	9,576	—	$0	9,576	SEC↗
POWELL MICHAEL	Director	P Buy	2013-07-15	2013-07-17	63,957	$6.03	$385.7K	203,152	SEC↗
POWELL MICHAEL	Director	J Other	2013-07-15	2013-07-17	139,195	—	$0	139,195	SEC↗
POWELL MICHAEL	Director	P Buy	2013-07-15	2013-07-17	322,809	$6.03	$1.95M	1,025,364	SEC↗
POWELL MICHAEL	Director	J Other	2013-07-15	2013-07-17	702,555	—	$0	702,555	SEC↗
POWELL MICHAEL	Director	P Buy	2013-07-15	2013-07-17	4,400	$6.03	$26.5K	13,976	SEC↗
Zisson Alex	Other	J Other	2013-07-15	2013-07-17	2,500,002	$6.00	$15.00M	2,500,002	SEC↗
TMP Associates II LP	10% Owner	J Other	2013-07-15	2013-07-17	1,751,393	$6.00	$10.51M	1,751,393	SEC↗
TMP Associates II LP	10% Owner	J Other	2013-07-15	2013-07-17	687,176	$6.00	$4.12M	687,176	SEC↗
Thomas, McNerney & Partners, L	10% Owner	J Other	2013-07-15	2013-07-17	1,675,677	$6.00	$10.05M	1,675,677	SEC↗
Thomas, McNerney & Partners, L	10% Owner	J Other	2013-07-15	2013-07-17	762,892	$6.00	$4.58M	762,892	SEC↗
Halak Brian K	10% Owner	P Buy	2013-07-15	2013-07-25	988,285	$6.03	$5.96M	988,285	SEC↗
Halak Brian K	10% Owner	P Buy	2013-07-15	2013-07-25	7,333	$6.03	$44.2K	7,333	SEC↗
BLAIR JAMES C	10% Owner	P Buy	2013-07-15	2013-07-31	331,873	$6.03	$2.00M	1,857,036	SEC↗
BLAIR JAMES C	10% Owner	P Buy	2013-07-15	2013-07-31	988,285	$6.03	$5.96M	988,285	SEC↗
BLAIR JAMES C	10% Owner	P Buy	2013-07-15	2013-07-31	7,333	$6.03	$44.2K	7,333	SEC↗
DOVEY BRIAN H	10% Owner	P Buy	2013-07-15	2013-07-31	988,285	$6.03	$5.96M	988,285	SEC↗
DOVEY BRIAN H	10% Owner	P Buy	2013-07-15	2013-07-31	331,873	$6.03	$2.00M	1,857,036	SEC↗
DOVEY BRIAN H	10% Owner	P Buy	2013-07-15	2013-07-31	7,333	$6.03	$44.2K	7,333	SEC↗
SCHOEMAKER KATHLEEN K	10% Owner	P Buy	2013-07-15	2013-07-31	331,873	$6.03	$2.00M	1,857,036	SEC↗
SCHOEMAKER KATHLEEN K	10% Owner	P Buy	2013-07-15	2013-07-31	7,333	$6.03	$44.2K	7,333	SEC↗
SCHOEMAKER KATHLEEN K	10% Owner	P Buy	2013-07-15	2013-07-31	988,285	$6.03	$5.96M	988,285	SEC↗
TREU JESSE I	10% Owner	P Buy	2013-07-15	2013-07-31	331,873	$6.03	$2.00M	1,857,036	SEC↗
TREU JESSE I	10% Owner	P Buy	2013-07-15	2013-07-31	7,333	$6.03	$44.2K	7,333	SEC↗
TREU JESSE I	10% Owner	P Buy	2013-07-15	2013-07-31	988,285	$6.03	$5.96M	988,285	SEC↗
Domain Partners VI, L.P.	10% Owner	P Buy	2013-07-15	2013-07-31	331,873	$6.03	$2.00M	1,857,036	SEC↗
VITULLO NICOLE	10% Owner	P Buy	2013-07-15	2013-07-31	7,333	$6.03	$44.2K	7,333	SEC↗
VITULLO NICOLE	10% Owner	P Buy	2013-07-15	2013-07-31	331,873	$6.03	$2.00M	1,857,036	SEC↗
VITULLO NICOLE	10% Owner	P Buy	2013-07-15	2013-07-31	988,285	$6.03	$5.96M	988,285	SEC↗
TMP Associates II LP	10% Owner	A Award deriv	2012-10-01	2013-07-17	161,855	$44.23	$7.16M	161,855	SEC↗
Thomas, McNerney & Partners, L	10% Owner	A Award deriv	2012-10-01	2013-07-17	161,855	$44.23	$7.16M	161,855	SEC↗
Zisson Alex	Other	A Award deriv	2012-08-07	2013-07-17	31,835	—	$0	31,835	SEC↗
TMP Associates II LP	10% Owner	A Award deriv	2012-08-07	2013-07-17	31,835	—	$0	31,835	SEC↗
Thomas, McNerney & Partners, L	10% Owner	A Award deriv	2012-08-07	2013-07-17	31,835	—	$0	31,835	SEC↗
TMP Associates II LP	10% Owner	A Award deriv	2012-03-30	2013-07-17	161,855	$44.23	$7.16M	161,855	SEC↗
Thomas, McNerney & Partners, L	10% Owner	A Award deriv	2012-03-30	2013-07-17	161,855	$44.23	$7.16M	161,855	SEC↗
Zisson Alex	Other	A Award deriv	2011-04-19	2013-07-17	25,000	—	$0	25,000	SEC↗
TMP Associates II LP	10% Owner	A Award deriv	2011-04-19	2013-07-17	25,000	—	$0	25,000	SEC↗
Thomas, McNerney & Partners, L	10% Owner	A Award deriv	2011-04-19	2013-07-17	25,000	—	$0	25,000	SEC↗
TMP Associates II LP	10% Owner	A Award deriv	2010-02-11	2013-07-17	25,000	—	$0	25,000	SEC↗
Thomas, McNerney & Partners, L	10% Owner	A Award deriv	2010-02-11	2013-07-17	25,000	—	$0	25,000	SEC↗
TMP Associates II LP	10% Owner	A Award deriv	2009-02-11	2013-07-17	25,000	—	$0	25,000	SEC↗
Thomas, McNerney & Partners, L	10% Owner	A Award deriv	2009-02-11	2013-07-17	25,000	—	$0	25,000	SEC↗
TMP Associates II LP	10% Owner	A Award deriv	2006-02-06	2013-07-17	100,000	—	$0	100,000	SEC↗
Thomas, McNerney & Partners, L	10% Owner	A Award deriv	2006-02-06	2013-07-17	100,000	—	$0	100,000	SEC↗