Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
$4.40M
22 trades · 4 insiders
Net · 90d
$-4.40M
Insiders on file
16
Daily buy vs sell · 90 days
■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Demopulos Gregory A MD | Chairman, CEO & President, Director | 85 | $25.2K | $10.39M | 2026-10-28 |
| Borges David J. | VP, Finance & CAO | 44 | $0 | $2.17M | 2026-09-23 |
| Cancelmo Peter B | VP, General Counsel | 21 | $0 | $1.86M | 2026-08-31 |
| HANISH ARNOLD C | Director | 40 | $11.2K | $596.5K | 2026-08-27 |
| Cable Thomas J. | Director | 61 | $0 | $1.67M | 2026-08-20 |
| Schocken Joseph L | Director | 2 | $0 | $0 | 2026-08-12 |
| Perkinson Diana T. | Director | 4 | $0 | $0 | 2026-06-18 |
| Bumol Thomas F. | Director | 10 | $0 | $0 | 2026-06-18 |
| Shah Rajiv | Director | 13 | $0 | $0 | 2026-06-18 |
| Hood Leroy E. MD PhD | Director | 22 | $0 | $0 | 2026-06-18 |
| Demopulos Peter A MD | Director | 31 | $365.9K | $0 | 2026-06-18 |
| JACOBSEN MICHAEL A | VP, Finance & CAO | 48 | $0 | $2.04M | 2024-04-25 |
| Zumwalt Kurt | Director | 5 | $0 | $0 | 2022-09-21 |
| Aspiri Ray | Director | 19 | $228.8K | $0 | 2021-06-11 |
| Kelbon Marcia S. | VP Patent and General Counsel | 91 | $0 | $5.68M | 2019-06-07 |
| SPIEGELMAN DANIEL K | Director | 1 | $0 | $0 | 2012-06-01 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Demopulos Gregory A MD | Chairman, CEO & President, D | A Award deriv | 2026-10-28 | 2026-10-30 | 500,000 | — | $0 | 500,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-09-23 | 2026-09-24 | 10,000 | — | $0 | 5,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | S Sale | 2026-09-23 | 2026-09-24 | 10,000 | $20.95 | $209.5K | 0 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-09-23 | 2026-09-24 | 10,000 | $15.58 | $155.8K | 10,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-09-23 | 2026-09-24 | 10,000 | — | $0 | 5,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | S Sale | 2026-09-23 | 2026-09-24 | 10,000 | $20.95 | $209.5K | 0 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-09-23 | 2026-09-24 | 10,000 | $15.58 | $155.8K | 10,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-09-22 | 2026-09-24 | 5,000 | — | $0 | 15,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-09-22 | 2026-09-24 | 5,000 | — | $0 | 4,094 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-09-22 | 2026-09-24 | 5,000 | $2.94 | $14.7K | 10,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-09-22 | 2026-09-24 | 5,000 | $3.93 | $19.6K | 5,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | S Sale | 2026-09-22 | 2026-09-24 | 10,000 | $20.95 | $209.5K | 0 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-09-22 | 2026-09-24 | 5,000 | — | $0 | 15,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-09-22 | 2026-09-24 | 5,000 | — | $0 | 4,094 | SEC↗ |
| Borges David J. | VP, Finance & CAO | S Sale | 2026-09-22 | 2026-09-24 | 10,000 | $20.95 | $209.5K | 0 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-09-22 | 2026-09-24 | 5,000 | $2.94 | $14.7K | 10,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-09-22 | 2026-09-24 | 5,000 | $3.93 | $19.6K | 5,000 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | M Exercise deriv | 2026-08-31 | 2026-09-01 | 25,000 | — | $0 | 50,000 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | M Exercise | 2026-08-31 | 2026-09-01 | 25,000 | $2.94 | $73.5K | 25,200 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | S Sale | 2026-08-31 | 2026-09-01 | 25,000 | $18.54 | $463.5K | 200 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | M Exercise deriv | 2026-08-31 | 2026-09-01 | 25,000 | — | $0 | 50,000 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | S Sale | 2026-08-31 | 2026-09-01 | 25,000 | $18.54 | $463.5K | 200 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | M Exercise | 2026-08-31 | 2026-09-01 | 25,000 | $2.94 | $73.5K | 25,200 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | M Exercise deriv | 2026-08-28 | 2026-09-01 | 25,000 | — | $0 | 75,000 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | S Sale | 2026-08-28 | 2026-09-01 | 25,000 | $18.65 | $466.2K | 200 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | M Exercise | 2026-08-28 | 2026-09-01 | 25,000 | $2.94 | $73.5K | 25,200 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | M Exercise deriv | 2026-08-28 | 2026-09-01 | 25,000 | — | $0 | 75,000 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | S Sale | 2026-08-28 | 2026-09-01 | 25,000 | $18.65 | $466.1K | 200 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | M Exercise | 2026-08-28 | 2026-09-01 | 25,000 | $2.94 | $73.5K | 25,200 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise deriv | 2026-08-27 | 2026-08-28 | 7,500 | — | $0 | 0 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise deriv | 2026-08-27 | 2026-08-28 | 2,500 | — | $0 | 0 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise | 2026-08-27 | 2026-08-28 | 2,500 | $15.81 | $39.5K | 2,500 | SEC↗ |
| HANISH ARNOLD C | Director | S Sale | 2026-08-27 | 2026-08-28 | 5,000 | $18.88 | $94.4K | 5,000 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise | 2026-08-27 | 2026-08-28 | 7,500 | $14.66 | $110.0K | 10,000 | SEC↗ |
| HANISH ARNOLD C | Director | S Sale | 2026-08-27 | 2026-08-28 | 5,000 | $19.02 | $95.1K | 0 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise deriv | 2026-08-27 | 2026-08-28 | 7,500 | — | $0 | 0 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise deriv | 2026-08-27 | 2026-08-28 | 2,500 | — | $0 | 0 | SEC↗ |
| HANISH ARNOLD C | Director | S Sale | 2026-08-27 | 2026-08-28 | 5,000 | $19.02 | $95.1K | 0 | SEC↗ |
| HANISH ARNOLD C | Director | S Sale | 2026-08-27 | 2026-08-28 | 5,000 | $18.88 | $94.4K | 5,000 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise | 2026-08-27 | 2026-08-28 | 7,500 | $14.66 | $110.0K | 10,000 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise | 2026-08-27 | 2026-08-28 | 2,500 | $15.81 | $39.5K | 2,500 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise deriv | 2026-08-26 | 2026-08-28 | 5,000 | — | $0 | 2,500 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise | 2026-08-26 | 2026-08-28 | 5,000 | $15.81 | $79.0K | 5,000 | SEC↗ |
| HANISH ARNOLD C | Director | S Sale | 2026-08-26 | 2026-08-28 | 5,000 | $18.53 | $92.7K | 0 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise deriv | 2026-08-26 | 2026-08-28 | 5,000 | — | $0 | 2,500 | SEC↗ |
| HANISH ARNOLD C | Director | S Sale | 2026-08-26 | 2026-08-28 | 5,000 | $18.53 | $92.6K | 0 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise | 2026-08-26 | 2026-08-28 | 5,000 | $15.81 | $79.0K | 5,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-08-24 | 2026-08-25 | 906 | — | $0 | 20,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-08-24 | 2026-08-25 | 906 | $2.94 | $2.7K | 906 | SEC↗ |
| Borges David J. | VP, Finance & CAO | S Sale | 2026-08-24 | 2026-08-25 | 906 | $19.10 | $17.3K | 0 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-08-24 | 2026-08-25 | 906 | — | $0 | 20,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | S Sale | 2026-08-24 | 2026-08-25 | 906 | $19.10 | $17.3K | 0 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-08-24 | 2026-08-25 | 906 | $2.94 | $2.7K | 906 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-08-21 | 2026-08-25 | 4,094 | — | $0 | 20,906 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-08-21 | 2026-08-25 | 5,906 | — | $0 | 9,094 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-08-21 | 2026-08-25 | 4,094 | $2.94 | $12.0K | 10,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | S Sale | 2026-08-21 | 2026-08-25 | 10,000 | $18.95 | $189.5K | 0 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-08-21 | 2026-08-25 | 5,906 | $3.93 | $23.2K | 5,906 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-08-21 | 2026-08-25 | 4,094 | — | $0 | 20,906 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-08-21 | 2026-08-25 | 5,906 | — | $0 | 9,094 | SEC↗ |
| Borges David J. | VP, Finance & CAO | S Sale | 2026-08-21 | 2026-08-25 | 10,000 | $18.95 | $189.5K | 0 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-08-21 | 2026-08-25 | 4,094 | $2.94 | $12.0K | 10,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-08-21 | 2026-08-25 | 5,906 | $3.93 | $23.2K | 5,906 | SEC↗ |
| Cable Thomas J. | Director | M Exercise deriv | 2026-08-20 | 2026-08-21 | 7,500 | — | $0 | 0 | SEC↗ |
| Cable Thomas J. | Director | M Exercise deriv | 2026-08-20 | 2026-08-21 | 7,500 | — | $0 | 0 | SEC↗ |
| Cable Thomas J. | Director | M Exercise | 2026-08-20 | 2026-08-21 | 7,500 | $3.93 | $29.5K | 50,067 | SEC↗ |
| Cable Thomas J. | Director | S Sale | 2026-08-20 | 2026-08-21 | 15,000 | $18.45 | $276.8K | 35,067 | SEC↗ |
| Cable Thomas J. | Director | M Exercise | 2026-08-20 | 2026-08-21 | 7,500 | $2.00 | $15.0K | 42,567 | SEC↗ |
| Cable Thomas J. | Director | M Exercise deriv | 2026-08-20 | 2026-08-21 | 7,500 | — | $0 | 0 | SEC↗ |
| Cable Thomas J. | Director | M Exercise deriv | 2026-08-20 | 2026-08-21 | 7,500 | — | $0 | 0 | SEC↗ |
| Cable Thomas J. | Director | S Sale | 2026-08-20 | 2026-08-21 | 15,000 | $18.45 | $276.8K | 35,067 | SEC↗ |
| Cable Thomas J. | Director | M Exercise | 2026-08-20 | 2026-08-21 | 7,500 | $3.93 | $29.5K | 50,067 | SEC↗ |
| Cable Thomas J. | Director | M Exercise | 2026-08-20 | 2026-08-21 | 7,500 | $2.00 | $15.0K | 42,567 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-08-13 | 2026-08-17 | 5,000 | — | $0 | 15,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-08-13 | 2026-08-17 | 5,000 | $3.93 | $19.6K | 5,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | S Sale | 2026-08-13 | 2026-08-17 | 5,000 | $16.95 | $84.8K | 0 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-08-13 | 2026-08-17 | 5,000 | — | $0 | 15,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | S Sale | 2026-08-13 | 2026-08-17 | 5,000 | $16.95 | $84.8K | 0 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-08-13 | 2026-08-17 | 5,000 | $3.93 | $19.6K | 5,000 | SEC↗ |
| Schocken Joseph L | Director | A Award deriv | 2026-08-12 | 2026-08-18 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Schocken Joseph L | Director | A Award deriv | 2026-08-12 | 2026-08-18 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | A Award deriv | 2026-07-22 | 2026-07-24 | 105,000 | — | $0 | 105,000 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | A Award deriv | 2026-07-22 | 2026-07-24 | 105,000 | — | $0 | 105,000 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | A Award deriv | 2026-07-22 | 2026-07-24 | 1,000,000 | — | $0 | 1,000,000 | SEC↗ |
| Bumol Thomas F. | Director | A Award deriv | 2026-06-18 | 2026-06-22 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Cable Thomas J. | Director | A Award deriv | 2026-06-18 | 2026-06-22 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Demopulos Peter A MD | Director | A Award deriv | 2026-06-18 | 2026-06-22 | 15,000 | — | $0 | 15,000 | SEC↗ |
| HANISH ARNOLD C | Director | A Award deriv | 2026-06-18 | 2026-06-22 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Hood Leroy E. MD PhD | Director | A Award deriv | 2026-06-18 | 2026-06-22 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Perkinson Diana T. | Director | A Award deriv | 2026-06-18 | 2026-06-22 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Shah Rajiv | Director | A Award deriv | 2026-06-18 | 2026-06-22 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Cable Thomas J. | Director | M Exercise deriv | 2026-05-22 | 2026-05-27 | 7,500 | — | $0 | 0 | SEC↗ |
| Cable Thomas J. | Director | M Exercise | 2026-05-22 | 2026-05-27 | 7,500 | $10.84 | $81.3K | 42,567 | SEC↗ |
| Cable Thomas J. | Director | S Sale | 2026-05-22 | 2026-05-27 | 7,500 | $11.61 | $87.1K | 35,067 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | M Exercise deriv | 2026-02-18 | 2026-02-20 | 400,000 | — | $0 | 0 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | M Exercise | 2026-02-18 | 2026-02-20 | 400,000 | $10.27 | $4.11M | 1,826,986 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | F Tax w/h | 2026-02-18 | 2026-02-20 | 357,678 | $11.93 | $4.27M | 1,469,308 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise deriv | 2026-01-13 | 2026-01-14 | 30,000 | — | $0 | 65,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | S Sale | 2026-01-13 | 2026-01-14 | 30,000 | $12.31 | $369.3K | 0 | SEC↗ |
| Borges David J. | VP, Finance & CAO | M Exercise | 2026-01-13 | 2026-01-14 | 30,000 | $3.06 | $91.8K | 30,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | S Sale | 2026-01-12 | 2026-01-14 | 30,000 | $12.72 | $381.6K | 0 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | G Gift | 2025-10-13 | 2025-10-15 | 600,000 | — | $0 | 1,426,986 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | G Gift | 2025-10-13 | 2025-10-15 | 300,000 | — | $0 | 300,000 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | G Gift | 2025-10-13 | 2025-10-15 | 300,000 | — | $0 | 300,000 | SEC↗ |
| Borges David J. | VP, Finance & CAO | A Award deriv | 2025-06-30 | 2025-07-01 | 95,000 | — | $0 | 95,000 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | A Award deriv | 2025-06-30 | 2025-07-01 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | A Award deriv | 2025-06-30 | 2025-07-01 | 865,000 | — | $0 | 865,000 | SEC↗ |
| Bumol Thomas F. | Director | A Award deriv | 2025-06-27 | 2025-07-01 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Cable Thomas J. | Director | A Award deriv | 2025-06-27 | 2025-07-01 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Demopulos Peter A MD | Director | A Award deriv | 2025-06-27 | 2025-07-01 | 15,000 | — | $0 | 15,000 | SEC↗ |
| HANISH ARNOLD C | Director | A Award deriv | 2025-06-27 | 2025-07-01 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Hood Leroy E. MD PhD | Director | A Award deriv | 2025-06-27 | 2025-07-01 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Perkinson Diana T. | Director | A Award deriv | 2025-06-27 | 2025-07-01 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Shah Rajiv | Director | A Award deriv | 2025-06-27 | 2025-07-01 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Bumol Thomas F. | Director | A Award deriv | 2024-06-06 | 2024-06-07 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Cable Thomas J. | Director | A Award deriv | 2024-06-06 | 2024-06-07 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Demopulos Peter A MD | Director | A Award deriv | 2024-06-06 | 2024-06-07 | 15,000 | — | $0 | 15,000 | SEC↗ |
| HANISH ARNOLD C | Director | A Award deriv | 2024-06-06 | 2024-06-07 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Hood Leroy E. MD PhD | Director | A Award deriv | 2024-06-06 | 2024-06-07 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Perkinson Diana T. | Director | A Award deriv | 2024-06-06 | 2024-06-07 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Shah Rajiv | Director | A Award deriv | 2024-06-06 | 2024-06-07 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | A Award deriv | 2024-04-25 | 2024-04-29 | 100,000 | — | $0 | 100,000 | SEC↗ |
| JACOBSEN MICHAEL A | VP, Finance & CAO | A Award deriv | 2024-04-25 | 2024-04-29 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | A Award deriv | 2024-04-25 | 2024-04-29 | 725,000 | — | $0 | 725,000 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | P Buy | 2023-11-17 | 2023-11-21 | 15,000 | $1.68 | $25.2K | 123,945 | SEC↗ |
| Demopulos Peter A MD | Director | P Buy | 2023-11-15 | 2023-11-17 | 10,000 | $1.53 | $15.3K | 208,516 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | A Award | 2023-11-14 | 2023-11-15 | 25,000 | $1.44 | $36.0K | 108,945 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | A Award | 2023-11-13 | 2023-11-15 | 37,500 | $1.29 | $48.4K | 83,945 | SEC↗ |
| Cancelmo Peter B | VP, General Counsel | A Award deriv | 2023-09-22 | 2023-09-27 | 100,000 | — | $0 | 100,000 | SEC↗ |
| JACOBSEN MICHAEL A | VP, Finance & CAO | A Award deriv | 2023-09-22 | 2023-09-27 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | A Award deriv | 2023-09-22 | 2023-09-27 | 715,000 | — | $0 | 715,000 | SEC↗ |
| Bumol Thomas F. | Director | A Award | 2023-09-12 | 2023-09-14 | 10,000 | $3.31 | $33.1K | 10,000 | SEC↗ |
| Cable Thomas J. | Director | A Award deriv | 2023-06-23 | 2023-06-27 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Bumol Thomas F. | Director | A Award deriv | 2023-06-23 | 2023-06-27 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Shah Rajiv | Director | A Award deriv | 2023-06-23 | 2023-06-27 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Demopulos Peter A MD | Director | A Award deriv | 2023-06-23 | 2023-06-27 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Hood Leroy E. MD PhD | Director | A Award deriv | 2023-06-23 | 2023-06-27 | 15,000 | — | $0 | 15,000 | SEC↗ |
| HANISH ARNOLD C | Director | A Award deriv | 2023-06-23 | 2023-06-27 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Cable Thomas J. | Director | M Exercise deriv | 2023-05-22 | 2023-05-23 | 5,000 | — | $0 | 0 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise deriv | 2023-05-22 | 2023-05-23 | 5,000 | — | $0 | 0 | SEC↗ |
| Cable Thomas J. | Director | M Exercise | 2023-05-22 | 2023-05-23 | 5,000 | $5.30 | $26.5K | 40,067 | SEC↗ |
| Cable Thomas J. | Director | S Sale | 2023-05-22 | 2023-05-23 | 5,000 | $6.53 | $32.6K | 35,067 | SEC↗ |
| HANISH ARNOLD C | Director | S Sale | 2023-05-22 | 2023-05-23 | 5,000 | $6.46 | $32.3K | 0 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise | 2023-05-22 | 2023-05-23 | 5,000 | $5.30 | $26.5K | 5,000 | SEC↗ |
| Perkinson Diana T. | Director | A Award deriv | 2023-05-12 | 2023-05-16 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Cancelmo Peter B | VP, GENERAL COUNSEL | A Award deriv | 2022-09-21 | 2022-09-23 | 80,000 | — | $0 | 80,000 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | A Award deriv | 2022-09-21 | 2022-09-23 | 85,000 | — | $0 | 85,000 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | A Award deriv | 2022-09-21 | 2022-09-23 | 650,000 | — | $0 | 650,000 | SEC↗ |
| HANISH ARNOLD C | Director | A Award deriv | 2022-09-21 | 2022-09-23 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Zumwalt Kurt | Director | A Award deriv | 2022-09-21 | 2022-09-23 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Hood Leroy E. MD PhD | Director | A Award deriv | 2022-09-21 | 2022-09-23 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Demopulos Peter A MD | Director | A Award deriv | 2022-09-21 | 2022-09-23 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Shah Rajiv | Director | A Award deriv | 2022-09-21 | 2022-09-23 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Bumol Thomas F. | Director | A Award deriv | 2022-09-21 | 2022-09-23 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Cable Thomas J. | Director | A Award deriv | 2022-09-21 | 2022-09-23 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Bumol Thomas F. | Director | A Award deriv | 2022-06-17 | 2022-06-22 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Cable Thomas J. | Director | A Award deriv | 2022-06-17 | 2022-06-22 | 7,500 | — | $0 | 7,500 | SEC↗ |
| HANISH ARNOLD C | Director | A Award deriv | 2022-06-17 | 2022-06-22 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Hood Leroy E. MD PhD | Director | A Award deriv | 2022-06-17 | 2022-06-22 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Demopulos Peter A MD | Director | A Award deriv | 2022-06-17 | 2022-06-22 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Shah Rajiv | Director | A Award deriv | 2022-06-17 | 2022-06-22 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Zumwalt Kurt | Director | A Award deriv | 2022-06-17 | 2022-06-22 | 7,500 | — | $0 | 7,500 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise deriv | 2021-09-08 | 2021-09-09 | 10,000 | — | $0 | 5,000 | SEC↗ |
| HANISH ARNOLD C | Director | M Exercise | 2021-09-08 | 2021-09-09 | 10,000 | $9.44 | $94.4K | 10,000 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | A Award deriv | 2021-07-02 | 2021-07-06 | 550,000 | — | $0 | 550,000 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | A Award deriv | 2021-07-02 | 2021-07-06 | 75,000 | — | $0 | 75,000 | SEC↗ |
| Cancelmo Peter B | VP, GEN. COUNSEL & CORP. SEC | A Award deriv | 2021-07-02 | 2021-07-06 | 75,000 | — | $0 | 75,000 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | M Exercise deriv | 2021-06-17 | 2021-06-17 | 36,857 | — | $0 | 0 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | M Exercise | 2021-06-17 | 2021-06-17 | 36,857 | $4.10 | $151.1K | 2,063,843 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | S Sale | 2021-06-17 | 2021-06-17 | 36,857 | $14.90 | $549.2K | 2,026,986 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | M Exercise deriv | 2021-06-15 | 2021-06-17 | 36,856 | — | $0 | 36,857 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | S Sale | 2021-06-15 | 2021-06-17 | 36,856 | $15.02 | $553.6K | 2,026,986 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | M Exercise | 2021-06-15 | 2021-06-17 | 36,856 | $4.10 | $151.1K | 2,063,842 | SEC↗ |
| Aspiri Ray | Director | A Award deriv | 2021-06-11 | 2022-02-14 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Bumol Thomas F. | Director | A Award deriv | 2021-06-11 | 2022-02-14 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Shah Rajiv | Director | A Award deriv | 2021-06-11 | 2022-02-14 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Demopulos Peter A MD | Director | A Award deriv | 2021-06-11 | 2022-02-14 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Hood Leroy E. MD PhD | Director | A Award deriv | 2021-06-11 | 2022-02-14 | 7,500 | — | $0 | 7,500 | SEC↗ |
| HANISH ARNOLD C | Director | A Award deriv | 2021-06-11 | 2022-02-14 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Cable Thomas J. | Director | A Award deriv | 2021-06-11 | 2022-02-14 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Zumwalt Kurt | Director | A Award deriv | 2021-06-11 | 2022-02-14 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | M Exercise deriv | 2021-05-20 | 2021-05-21 | 36,856 | — | $0 | 73,713 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | S Sale | 2021-05-20 | 2021-05-21 | 36,856 | $14.96 | $551.4K | 2,026,986 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | M Exercise | 2021-05-20 | 2021-05-21 | 36,856 | $4.10 | $151.1K | 2,063,842 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | M Exercise deriv | 2021-05-19 | 2021-05-21 | 36,857 | — | $0 | 110,569 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | M Exercise | 2021-05-19 | 2021-05-21 | 36,857 | $4.10 | $151.1K | 2,063,843 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | S Sale | 2021-05-19 | 2021-05-21 | 36,857 | $17.07 | $629.1K | 2,026,986 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | M Exercise deriv | 2021-04-08 | 2021-04-08 | 35,206 | — | $0 | 147,426 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | S Sale | 2021-04-08 | 2021-04-08 | 35,206 | $17.76 | $625.3K | 2,026,986 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | M Exercise | 2021-04-08 | 2021-04-08 | 35,206 | $4.10 | $144.3K | 2,062,192 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | M Exercise deriv | 2021-04-07 | 2021-04-08 | 37,407 | — | $0 | 182,632 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | S Sale | 2021-04-07 | 2021-04-08 | 37,407 | $17.91 | $670.0K | 2,026,986 | SEC↗ |
| Demopulos Gregory A MD | CHAIRMAN, CEO & PRESIDENT | M Exercise | 2021-04-07 | 2021-04-08 | 37,407 | $4.10 | $153.4K | 2,064,393 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | M Exercise deriv | 2021-02-22 | 2021-02-23 | 8,100 | — | $0 | 65,000 | SEC↗ |
| Demopulos Peter A MD | Director | M Exercise deriv | 2021-02-22 | 2021-02-23 | 5,000 | — | $0 | 0 | SEC↗ |
| Demopulos Peter A MD | Director | M Exercise deriv | 2021-02-22 | 2021-02-23 | 5,000 | — | $0 | 0 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | M Exercise | 2021-02-22 | 2021-02-23 | 8,100 | $10.27 | $83.2K | 22,100 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | S Sale | 2021-02-22 | 2021-02-23 | 8,100 | $23.28 | $188.6K | 14,000 | SEC↗ |
| Demopulos Peter A MD | Director | M Exercise | 2021-02-22 | 2021-02-23 | 5,000 | $5.30 | $26.5K | 193,516 | SEC↗ |
| Demopulos Peter A MD | Director | M Exercise | 2021-02-22 | 2021-02-23 | 5,000 | $4.53 | $22.6K | 198,516 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | M Exercise deriv | 2021-02-19 | 2021-02-23 | 10,000 | — | $0 | 73,100 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | S Sale | 2021-02-19 | 2021-02-23 | 10,000 | $22.64 | $226.4K | 14,000 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | M Exercise | 2021-02-19 | 2021-02-23 | 10,000 | $10.27 | $102.7K | 24,000 | SEC↗ |
| Hood Leroy E. MD PhD | Director | M Exercise deriv | 2021-02-12 | 2021-02-17 | 5,000 | — | $0 | 0 | SEC↗ |
| Hood Leroy E. MD PhD | Director | M Exercise | 2021-02-12 | 2021-02-17 | 5,000 | $4.53 | $22.6K | 74,390 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | S Sale | 2021-02-10 | 2021-02-12 | 1,900 | $22.49 | $42.7K | 14,000 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | M Exercise | 2021-02-10 | 2021-02-12 | 1,900 | $10.27 | $19.5K | 15,900 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | M Exercise deriv | 2021-01-20 | 2021-01-21 | 10,000 | $9.37 | $93.7K | 19,188 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | M Exercise deriv | 2021-01-20 | 2021-02-12 | 1,900 | — | $0 | 83,100 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | M Exercise | 2021-01-20 | 2021-01-21 | 10,000 | $9.37 | $93.7K | 14,000 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | S Sale | 2021-01-19 | 2021-01-21 | 9,500 | $19.95 | $189.5K | 4,000 | SEC↗ |
| Cable Thomas J. | Director | M Exercise deriv | 2021-01-13 | 2021-01-15 | 5,000 | — | $0 | 0 | SEC↗ |
| Cable Thomas J. | Director | M Exercise | 2021-01-13 | 2021-01-15 | 5,000 | $4.53 | $22.6K | 40,067 | SEC↗ |
| Cable Thomas J. | Director | S Sale | 2021-01-13 | 2021-01-15 | 5,000 | $16.97 | $84.8K | 35,067 | SEC↗ |
| Cancelmo Peter B | VP, GEN. COUNSEL & CORP. SEC | A Award deriv | 2020-10-26 | 2020-10-28 | 20,000 | — | $0 | 20,000 | SEC↗ |
| HANISH ARNOLD C | Director | A Award deriv | 2020-06-05 | 2020-06-09 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Bumol Thomas F. | Director | A Award deriv | 2020-06-05 | 2020-06-09 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Shah Rajiv | Director | A Award deriv | 2020-06-05 | 2020-06-09 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Aspiri Ray | Director | A Award deriv | 2020-06-05 | 2020-06-09 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Hood Leroy E. MD PhD | Director | A Award deriv | 2020-06-05 | 2020-06-09 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Demopulos Peter A MD | Director | A Award deriv | 2020-06-05 | 2020-06-09 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Cable Thomas J. | Director | A Award deriv | 2020-06-05 | 2020-06-09 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Cable Thomas J. | Director | M Exercise deriv | 2020-05-13 | 2020-05-15 | 5,000 | — | $0 | 0 | SEC↗ |
| Cable Thomas J. | Director | M Exercise | 2020-05-13 | 2020-05-15 | 5,000 | $5.92 | $29.6K | 40,067 | SEC↗ |
| Cable Thomas J. | Director | S Sale | 2020-05-13 | 2020-05-15 | 5,000 | $14.40 | $72.0K | 35,067 | SEC↗ |
| Hood Leroy E. MD PhD | Director | M Exercise deriv | 2020-03-13 | 2020-03-17 | 5,000 | — | $0 | 0 | SEC↗ |
| Hood Leroy E. MD PhD | Director | M Exercise | 2020-03-13 | 2020-03-17 | 5,000 | $5.92 | $29.6K | 69,390 | SEC↗ |
| Cancelmo Peter B | VP, GEN. COUNSEL & CORP. SEC | A Award deriv | 2020-03-01 | 2020-03-03 | 50,000 | — | $0 | 50,000 | SEC↗ |
| JACOBSEN MICHAEL A | VP FINANCE AND CAO | A Award deriv | 2020-03-01 | 2020-03-03 | 70,000 | — | $0 | 70,000 | SEC↗ |
| Demopulos Gregory A MD | CHIARMAN, CEO & PRESIDENT | A Award deriv | 2020-03-01 | 2020-03-03 | 450,000 | — | $0 | 450,000 | SEC↗ |
| Zumwalt Kurt | Director | A Award deriv | 2020-02-10 | 2020-02-12 | 11,750 | — | $0 | 11,750 | SEC↗ |
| Zumwalt Kurt | Director | A Award deriv | 2020-02-10 | 2020-02-12 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Demopulos Peter A MD | Director | M Exercise deriv | 2019-12-14 | 2019-12-17 | 3,334 | — | $0 | 0 | SEC↗ |
| Hood Leroy E. MD PhD | Director | M Exercise deriv | 2019-12-14 | 2019-12-17 | 10,000 | — | $0 | 0 | SEC↗ |
| Demopulos Peter A MD | Director | M Exercise | 2019-12-14 | 2019-12-17 | 3,334 | $7.56 | $25.2K | 188,516 | SEC↗ |
| Hood Leroy E. MD PhD | Director | M Exercise | 2019-12-14 | 2019-12-17 | 10,000 | $7.56 | $75.6K | 64,390 | SEC↗ |
| Cable Thomas J. | Director | M Exercise deriv | 2019-12-03 | 2019-12-05 | 10,000 | — | $0 | 0 | SEC↗ |
| Cable Thomas J. | Director | M Exercise | 2019-12-03 | 2019-12-05 | 10,000 | $7.56 | $75.6K | 45,067 | SEC↗ |
| Cable Thomas J. | Director | S Sale | 2019-12-03 | 2019-12-05 | 10,000 | $14.41 | $144.1K | 35,067 | SEC↗ |
| Cable Thomas J. | Director | S Sale | 2019-10-14 | 2019-10-16 | 5,000 | $15.12 | $75.6K | 35,067 | SEC↗ |
| Cancelmo Peter B | See Remarks | A Award deriv | 2019-06-10 | 2019-06-11 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise deriv | 2019-06-07 | 2019-06-11 | 10,000 | — | $0 | 43,996 | SEC↗ |
| Aspiri Ray | Director | A Award deriv | 2019-06-07 | 2019-06-11 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Cable Thomas J. | Director | A Award deriv | 2019-06-07 | 2019-06-11 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Demopulos Peter A MD | Director | A Award deriv | 2019-06-07 | 2019-06-11 | 7,500 | — | $0 | 7,500 | SEC↗ |
| HANISH ARNOLD C | Director | A Award deriv | 2019-06-07 | 2019-06-11 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Hood Leroy E. MD PhD | Director | A Award deriv | 2019-06-07 | 2019-06-11 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Shah Rajiv | Director | A Award deriv | 2019-06-07 | 2019-06-11 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise | 2019-06-07 | 2019-06-11 | 10,000 | $6.05 | $60.5K | 210,645 | SEC↗ |
| Bumol Thomas F. | Director | A Award deriv | 2019-02-09 | 2019-02-12 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | A Award deriv | 2019-02-08 | 2019-02-12 | 425,000 | — | $0 | 425,000 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | A Award deriv | 2019-02-08 | 2019-02-12 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | A Award deriv | 2019-02-08 | 2019-02-12 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise deriv | 2018-08-31 | 2018-08-31 | 8,000 | — | $0 | 53,996 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise deriv | 2018-08-31 | 2018-08-31 | 7,529 | — | $0 | 0 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | S Sale | 2018-08-31 | 2018-08-31 | 5,337 | $25.93 | $138.4K | 192,645 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | S Sale | 2018-08-31 | 2018-08-31 | 2,192 | $25.31 | $55.5K | 197,982 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise | 2018-08-31 | 2018-08-31 | 8,000 | $6.05 | $48.4K | 200,645 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise | 2018-08-31 | 2018-08-31 | 7,529 | $4.10 | $30.9K | 200,174 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise deriv | 2018-08-30 | 2018-08-31 | 35,000 | — | $0 | 7,529 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | S Sale | 2018-08-30 | 2018-08-31 | 35,000 | $24.45 | $855.8K | 192,645 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise | 2018-08-30 | 2018-08-31 | 35,000 | $4.10 | $143.5K | 227,645 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise deriv | 2018-07-27 | 2018-07-30 | 5,723 | — | $0 | 42,529 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | S Sale | 2018-07-27 | 2018-07-30 | 5,723 | $21.73 | $124.4K | 192,645 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise | 2018-07-27 | 2018-07-30 | 5,723 | $4.10 | $23.5K | 198,368 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise deriv | 2018-07-26 | 2018-07-30 | 8,000 | — | $0 | 61,996 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise deriv | 2018-07-26 | 2018-07-30 | 35,000 | — | $0 | 48,252 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise | 2018-07-26 | 2018-07-30 | 35,000 | $4.10 | $143.5K | 219,645 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise | 2018-07-26 | 2018-07-30 | 8,000 | $6.05 | $48.4K | 192,645 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | S Sale | 2018-07-26 | 2018-07-30 | 35,000 | $21.53 | $753.5K | 184,645 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise deriv | 2018-07-12 | 2018-07-13 | 4,277 | — | $0 | 83,252 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | S Sale | 2018-07-12 | 2018-07-13 | 4,277 | $21.48 | $91.9K | 184,645 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise | 2018-07-12 | 2018-07-13 | 4,277 | $4.10 | $17.5K | 188,922 | SEC↗ |
| Aspiri Ray | Director | A Award deriv | 2018-06-15 | 2018-06-18 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Cable Thomas J. | Director | A Award deriv | 2018-06-15 | 2018-06-18 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Demopulos Peter A MD | Director | A Award deriv | 2018-06-15 | 2018-06-18 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Hood Leroy E. MD PhD | Director | A Award deriv | 2018-06-15 | 2018-06-18 | 7,500 | — | $0 | 7,500 | SEC↗ |
| HANISH ARNOLD C | Director | A Award deriv | 2018-06-15 | 2018-06-18 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Shah Rajiv | Director | A Award deriv | 2018-06-15 | 2018-06-18 | 7,500 | — | $0 | 7,500 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | M Exercise deriv | 2018-05-15 | 2018-05-16 | 12,812 | — | $0 | 34,188 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | M Exercise deriv | 2018-05-15 | 2018-05-16 | 5,000 | — | $0 | 29,188 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | M Exercise | 2018-05-15 | 2018-05-16 | 12,812 | $9.37 | $120.0K | 21,312 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | S Sale | 2018-05-15 | 2018-05-16 | 12,812 | $24.95 | $319.7K | 8,500 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | M Exercise | 2018-05-15 | 2018-05-16 | 5,000 | $9.37 | $46.8K | 13,500 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | M Exercise deriv | 2018-05-14 | 2018-05-16 | 10,980 | — | $0 | 47,000 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | M Exercise | 2018-05-14 | 2018-05-16 | 10,980 | $9.37 | $102.9K | 19,480 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | S Sale | 2018-05-14 | 2018-05-16 | 10,980 | $22.45 | $246.5K | 8,500 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | A Award deriv | 2018-04-08 | 2018-04-10 | 65,000 | — | $0 | 65,000 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | A Award deriv | 2018-04-08 | 2018-04-10 | 60,000 | — | $0 | 60,000 | SEC↗ |
| Demopulos Gregory A MD | Chairman, CEO & President | A Award deriv | 2018-04-08 | 2018-04-11 | 350,000 | — | $0 | 350,000 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | M Exercise deriv | 2018-01-04 | 2018-01-05 | 1,000 | — | $0 | 57,980 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | M Exercise | 2018-01-04 | 2018-01-05 | 1,000 | $9.37 | $9.4K | 8,500 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | M Exercise deriv | 2018-01-03 | 2018-01-05 | 1,020 | — | $0 | 58,980 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise deriv | 2018-01-03 | 2018-01-05 | 3,000 | — | $0 | 0 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise deriv | 2018-01-03 | 2018-01-05 | 62,528 | — | $0 | 40,972 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise deriv | 2018-01-03 | 2018-01-05 | 5,004 | — | $0 | 69,996 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | M Exercise | 2018-01-03 | 2018-01-05 | 1,020 | $9.37 | $9.6K | 8,520 | SEC↗ |
| JACOBSEN MICHAEL A | VP Finance and CAO | S Sale | 2018-01-03 | 2018-01-05 | 1,020 | $22.45 | $22.9K | 7,500 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise | 2018-01-03 | 2018-01-05 | 5,004 | $6.05 | $30.3K | 184,645 | SEC↗ |
| Kelbon Marcia S. | VP Patent and General Counse | M Exercise | 2018-01-03 | 2018-01-05 | 3,000 | $6.05 | $18.1K | 179,641 | SEC↗ |