Open-mkt buys · 90d
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0 trades · 0 insiders
Open-mkt sales · 90d
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0 trades · 0 insiders
Net · 90d
$0
Insiders on file
28
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| SBLENDORIO GLENN | President, CFO and Treasurer | 38 | $22.0K | $506.2K | 2019-04-02 |
| Versant Side Fund IV, L.P. | 10% Owner | 2 | $0 | $0 | 2019-01-14 |
| Westby Keith | SVP & COO | 16 | $0 | $3.0K | 2019-01-07 |
| GUYER DAVID R | Executive Chairman | 193 | $0 | $29.88M | 2019-01-07 |
| Roberts Calvin W. | Director | 1 | $0 | $0 | 2019-01-01 |
| Carroll David Francis | SVP, CFO and Treasurer | 10 | $0 | $15.8K | 2018-12-12 |
| Graves Adrienne L | Director | 1 | $0 | $0 | 2018-12-12 |
| Redlick David E | Director | 8 | $0 | $1.8K | 2018-05-23 |
| Bolte Axel | Director | 6 | $267.5K | $29.0K | 2018-05-23 |
| Henderson Jane | Director | 2 | $0 | $0 | 2018-05-23 |
| Ross Michael Jay | Director | 11 | $0 | $0 | 2018-05-23 |
| WOOD BARBARA A | SVP,General Counsel,Secretary | 52 | $0 | $684.8K | 2018-01-05 |
| Bjarke Henric Bjorn | SVP & CCO | 6 | $0 | $1.6K | 2017-01-05 |
| PATEL SAMIR CHANDRAKANT | President | 191 | $0 | $28.59M | 2017-01-05 |
| Novo A/S | 10% Owner | 12 | $10.01M | $173.30M | 2016-12-15 |
| SMITH IAN F | Director | 1 | $0 | $0 | 2016-08-02 |
| GALAKATOS NICHOLAS | Director, 10% Owner | 33 | $110.0K | $7.14M | 2016-01-11 |
| ATIEH MICHAEL G | EVP,CFO & CBO, Treasurer | 10 | $0 | $9.4K | 2016-01-04 |
| SMITH TODD N | SVP & CCO | 3 | $0 | $0 | 2015-01-02 |
| PEACOCK BRUCE | CFO & CBO | 32 | $0 | $1.92M | 2014-09-02 |
| Clarus Lifesciences II, L.P. | 10% Owner | 7 | $0 | $9.61M | 2014-06-11 |
| SV LIFE SCIENCES FUND IV STRATEGIC PARTNERS, L. P. | 10% Owner | 8 | $0 | $146.19M | 2014-06-04 |
| SV LIFE SCIENCES FUND IV, L.P. | 10% Owner | 8 | $0 | $75.83M | 2014-06-03 |
| SVLSF IV, LLC | 10% Owner | 36 | $0 | $50.79M | 2014-05-30 |
| SV Life Sciences Fund IV (GP), L.P. | 10% Owner | 8 | $0 | $39.39M | 2014-05-28 |
| HBM Healthcare Investments (Cayman) Ltd. | 10% Owner | 10 | $5.02M | $14.88M | 2014-05-13 |
| Dyrberg Thomas | Director | 2 | $15.4K | $0 | 2013-10-23 |
| LIPTAK ROBERT | 10% Owner | 4 | $0 | $0 | 2013-09-30 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| SBLENDORIO GLENN | President and CEO | S Sale | 2019-04-02 | 2019-04-03 | 6,914 | $1.43 | $9.9K | 68,105 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | M Exercise deriv | 2019-04-01 | 2019-04-03 | 18,750 | — | $0 | 18,750 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | M Exercise | 2019-04-01 | 2019-04-03 | 18,750 | — | $0 | 75,019 | SEC↗ |
| Versant Side Fund IV, L.P. | 10% Owner | J Other | 2019-01-14 | 2019-01-16 | 129,709 | $2.30 | $298.3K | 5,142,333 | SEC↗ |
| Versant Side Fund IV, L.P. | 10% Owner | J Other | 2019-01-14 | 2019-01-16 | 817 | $2.30 | $1.9K | 32,394 | SEC↗ |
| GUYER DAVID R | Executive Chairman | S Sale | 2019-01-07 | 2019-01-07 | 3,859 | $1.30 | $5.0K | 43,164 | SEC↗ |
| Westby Keith | SVP & COO | S Sale | 2019-01-07 | 2019-01-07 | 299 | $1.30 | $389 | 32,606 | SEC↗ |
| GUYER DAVID R | Executive Chairman | M Exercise deriv | 2019-01-04 | 2019-01-07 | 6,250 | — | $0 | 6,250 | SEC↗ |
| Westby Keith | SVP & COO | M Exercise deriv | 2019-01-04 | 2019-01-07 | 700 | — | $0 | 700 | SEC↗ |
| GUYER DAVID R | Executive Chairman | M Exercise | 2019-01-04 | 2019-01-07 | 6,250 | — | $0 | 47,023 | SEC↗ |
| Westby Keith | SVP & COO | M Exercise | 2019-01-04 | 2019-01-07 | 700 | — | $0 | 32,905 | SEC↗ |
| GUYER DAVID R | Executive Chairman | S Sale | 2019-01-03 | 2019-01-04 | 3,637 | $1.24 | $4.5K | 40,773 | SEC↗ |
| Westby Keith | SVP & COO | S Sale | 2019-01-03 | 2019-01-04 | 342 | $1.24 | $424 | 32,205 | SEC↗ |
| GUYER DAVID R | Executive Chairman | M Exercise deriv | 2019-01-02 | 2019-01-04 | 5,750 | — | $0 | 0 | SEC↗ |
| Westby Keith | SVP & COO | M Exercise deriv | 2019-01-02 | 2019-01-04 | 781 | — | $0 | 0 | SEC↗ |
| GUYER DAVID R | Executive Chairman | M Exercise | 2019-01-02 | 2019-01-04 | 5,750 | — | $0 | 44,410 | SEC↗ |
| Westby Keith | SVP & COO | M Exercise | 2019-01-02 | 2019-01-04 | 781 | — | $0 | 32,547 | SEC↗ |
| Roberts Calvin W. | Director | A Award deriv | 2019-01-01 | 2019-01-03 | 32,000 | — | $0 | 32,000 | SEC↗ |
| Graves Adrienne L | Director | A Award deriv | 2018-12-12 | 2018-12-14 | 32,000 | — | $0 | 32,000 | SEC↗ |
| Carroll David Francis | SVP, CFO and Treasurer | A Award deriv | 2018-12-12 | 2018-12-14 | 50,000 | — | $0 | 50,000 | SEC↗ |
| Carroll David Francis | SVP, CFO and Treasurer | A Award deriv | 2018-12-12 | 2018-12-14 | 100,000 | — | $0 | 100,000 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | A Award deriv | 2018-12-12 | 2018-12-14 | 91,800 | — | $0 | 91,800 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | A Award deriv | 2018-12-12 | 2018-12-14 | 183,500 | — | $0 | 183,500 | SEC↗ |
| Westby Keith | SVP & COO | A Award deriv | 2018-12-12 | 2018-12-14 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Westby Keith | SVP & COO | A Award deriv | 2018-12-12 | 2018-12-14 | 50,000 | — | $0 | 50,000 | SEC↗ |
| GUYER DAVID R | Executive Chairman | A Award deriv | 2018-12-12 | 2018-12-14 | 137,500 | — | $0 | 137,500 | SEC↗ |
| GUYER DAVID R | Executive Chairman | A Award deriv | 2018-12-12 | 2018-12-14 | 68,800 | — | $0 | 68,800 | SEC↗ |
| Carroll David Francis | SVP, CFO and Treasurer | S Sale | 2018-07-02 | 2018-07-03 | 2,736 | $2.68 | $7.3K | 8,980 | SEC↗ |
| Carroll David Francis | SVP, CFO and Treasurer | M Exercise deriv | 2018-07-01 | 2018-07-03 | 7,500 | — | $0 | 15,000 | SEC↗ |
| Carroll David Francis | SVP, CFO and Treasurer | M Exercise | 2018-07-01 | 2018-07-03 | 7,500 | — | $0 | 11,716 | SEC↗ |
| Redlick David E | Director | A Award deriv | 2018-05-23 | 2018-07-11 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Henderson Jane | Director | A Award deriv | 2018-05-23 | 2018-07-11 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Bolte Axel | Director | A Award deriv | 2018-05-23 | 2018-07-11 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Ross Michael Jay | Director | A Award deriv | 2018-05-23 | 2018-07-11 | 16,000 | — | $0 | 16,000 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | S Sale | 2018-04-02 | 2018-04-03 | 6,838 | $2.69 | $18.4K | 48,407 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | M Exercise deriv | 2018-04-01 | 2018-04-03 | 18,750 | — | $0 | 37,500 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | M Exercise | 2018-04-01 | 2018-04-03 | 18,750 | — | $0 | 55,245 | SEC↗ |
| Henderson Jane | Director | A Award deriv | 2018-01-13 | 2018-01-17 | 32,000 | — | $0 | 32,000 | SEC↗ |
| GUYER DAVID R | Executive Chairman | S Sale | 2018-01-05 | 2018-01-05 | 3,798 | $3.17 | $12.0K | 38,660 | SEC↗ |
| Westby Keith | SVP & COO | S Sale | 2018-01-05 | 2018-01-05 | 317 | $3.17 | $1.0K | 24,983 | SEC↗ |
| WOOD BARBARA A | SVP, Gen. Counsel, Secretary | S Sale | 2018-01-05 | 2018-01-05 | 602 | $3.17 | $1.9K | 16,462 | SEC↗ |
| GUYER DAVID R | Executive Chairman | M Exercise deriv | 2018-01-04 | 2018-01-05 | 6,250 | — | $0 | 12,500 | SEC↗ |
| Westby Keith | SVP & COO | M Exercise deriv | 2018-01-04 | 2018-01-05 | 700 | — | $0 | 1,400 | SEC↗ |
| WOOD BARBARA A | SVP, Gen. Counsel, Secretary | M Exercise deriv | 2018-01-04 | 2018-01-05 | 1,200 | — | $0 | 2,400 | SEC↗ |
| GUYER DAVID R | Executive Chairman | M Exercise | 2018-01-04 | 2018-01-05 | 6,250 | — | $0 | 42,458 | SEC↗ |
| Westby Keith | SVP & COO | M Exercise | 2018-01-04 | 2018-01-05 | 700 | — | $0 | 25,300 | SEC↗ |
| WOOD BARBARA A | SVP, Gen. Counsel, Secretary | M Exercise | 2018-01-04 | 2018-01-05 | 1,200 | — | $0 | 17,064 | SEC↗ |
| Westby Keith | SVP & COO | S Sale | 2018-01-03 | 2018-01-04 | 356 | $3.24 | $1.2K | 24,600 | SEC↗ |
| WOOD BARBARA A | SVP, General Counsel,Secreta | S Sale | 2018-01-03 | 2018-01-04 | 694 | $3.24 | $2.2K | 15,864 | SEC↗ |
| GUYER DAVID R | Executive Chairman | S Sale | 2018-01-03 | 2018-01-04 | 3,516 | $3.24 | $11.4K | 36,208 | SEC↗ |
| Westby Keith | SVP & COO | M Exercise deriv | 2018-01-02 | 2018-01-04 | 781 | — | $0 | 781 | SEC↗ |
| WOOD BARBARA A | SVP, General Counsel,Secreta | M Exercise deriv | 2018-01-02 | 2018-01-04 | 1,375 | — | $0 | 1,375 | SEC↗ |
| GUYER DAVID R | Executive Chairman | M Exercise deriv | 2018-01-02 | 2018-01-04 | 5,750 | — | $0 | 5,750 | SEC↗ |
| GUYER DAVID R | Executive Chairman | S Sale | 2018-01-02 | 2018-01-03 | 16,520 | $3.19 | $52.7K | 33,974 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | S Sale | 2018-01-02 | 2018-01-03 | 8,089 | $3.19 | $25.8K | 36,495 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | S Sale | 2018-01-02 | 2018-01-03 | 5,289 | $3.19 | $16.9K | 15,183 | SEC↗ |
| Westby Keith | SVP & COO | M Exercise | 2018-01-02 | 2018-01-04 | 781 | — | $0 | 24,956 | SEC↗ |
| WOOD BARBARA A | SVP, General Counsel,Secreta | M Exercise | 2018-01-02 | 2018-01-04 | 1,375 | — | $0 | 16,558 | SEC↗ |
| GUYER DAVID R | Executive Chairman | M Exercise | 2018-01-02 | 2018-01-04 | 5,750 | — | $0 | 39,724 | SEC↗ |
| GUYER DAVID R | Executive Chairman | M Exercise deriv | 2017-12-29 | 2018-01-03 | 30,480 | — | $0 | 0 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | M Exercise deriv | 2017-12-29 | 2018-01-03 | 20,420 | — | $0 | 0 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | M Exercise deriv | 2017-12-29 | 2018-01-03 | 12,140 | — | $0 | 0 | SEC↗ |
| GUYER DAVID R | Executive Chairman | M Exercise | 2017-12-29 | 2018-01-03 | 30,480 | — | $0 | 50,494 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | M Exercise | 2017-12-29 | 2018-01-03 | 20,420 | — | $0 | 44,584 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | M Exercise | 2017-12-29 | 2018-01-03 | 12,140 | — | $0 | 20,472 | SEC↗ |
| Westby Keith | SVP & COO | A Award deriv | 2017-12-19 | 2017-12-21 | 150,000 | — | $0 | 150,000 | SEC↗ |
| GUYER DAVID R | Executive Chairman | A Award deriv | 2017-12-19 | 2017-12-21 | 300,000 | — | $0 | 300,000 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | A Award deriv | 2017-12-19 | 2017-12-21 | 400,000 | — | $0 | 400,000 | SEC↗ |
| Carroll David Francis | SVP, CFO and Treasurer | A Award deriv | 2017-12-19 | 2017-12-21 | 150,000 | — | $0 | 150,000 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | S Sale | 2017-07-05 | 2017-07-05 | 7,828 | $2.58 | $20.2K | 24,164 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | S Sale | 2017-07-05 | 2017-07-05 | 5,119 | $2.58 | $13.2K | 8,332 | SEC↗ |
| GUYER DAVID R | Executive Chairman | S Sale | 2017-07-05 | 2017-07-05 | 17,678 | $2.58 | $45.6K | 20,014 | SEC↗ |
| Carroll David Francis | SVP, CFO and Treasurer | S Sale | 2017-07-05 | 2017-07-05 | 3,284 | $2.58 | $8.5K | 4,216 | SEC↗ |
| Carroll David Francis | SVP, CFO and Treasurer | M Exercise deriv | 2017-07-01 | 2017-07-05 | 7,500 | — | $0 | 22,500 | SEC↗ |
| Carroll David Francis | SVP, CFO and Treasurer | M Exercise | 2017-07-01 | 2017-07-05 | 7,500 | — | $0 | 7,500 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | M Exercise deriv | 2017-06-30 | 2017-07-05 | 20,420 | — | $0 | 20,420 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | M Exercise deriv | 2017-06-30 | 2017-07-05 | 12,140 | — | $0 | 12,140 | SEC↗ |
| GUYER DAVID R | Executive Chairman | M Exercise deriv | 2017-06-30 | 2017-07-05 | 30,480 | — | $0 | 30,480 | SEC↗ |
| SBLENDORIO GLENN | President and CEO | M Exercise | 2017-06-30 | 2017-07-05 | 20,420 | — | $0 | 31,992 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | M Exercise | 2017-06-30 | 2017-07-05 | 12,140 | — | $0 | 13,451 | SEC↗ |
| GUYER DAVID R | Executive Chairman | M Exercise | 2017-06-30 | 2017-07-05 | 30,480 | — | $0 | 37,692 | SEC↗ |
| Redlick David E | Director | S Sale | 2017-06-13 | 2017-06-14 | 700 | $2.52 | $1.8K | 1,050 | SEC↗ |
| ROSS MICHAEL JAY | Director | A Award deriv | 2017-05-19 | 2017-05-22 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Redlick David E | Director | A Award deriv | 2017-05-19 | 2017-05-22 | 16,000 | — | $0 | 16,000 | SEC↗ |
| Bolte Axel | Director | A Award deriv | 2017-05-19 | 2017-05-22 | 16,000 | — | $0 | 16,000 | SEC↗ |
| ROSS MICHAEL JAY | Director | M Exercise deriv | 2017-05-18 | 2017-05-22 | 1,750 | — | $0 | 0 | SEC↗ |
| Redlick David E | Director | M Exercise deriv | 2017-05-18 | 2017-05-22 | 1,750 | — | $0 | 0 | SEC↗ |
| ROSS MICHAEL JAY | Director | M Exercise | 2017-05-18 | 2017-05-22 | 1,750 | — | $0 | 3,500 | SEC↗ |
| Redlick David E | Director | M Exercise | 2017-05-18 | 2017-05-22 | 1,750 | — | $0 | 1,750 | SEC↗ |
| Carroll David Francis | SVP, CFO and Treasurer | A Award deriv | 2017-04-24 | 2017-04-25 | 63,500 | — | $0 | 63,500 | SEC↗ |
| SBLENDORIO GLENN | President, CFO and Treasurer | S Sale | 2017-04-03 | 2017-04-04 | 7,388 | $3.56 | $26.3K | 11,572 | SEC↗ |
| SBLENDORIO GLENN | President, CFO and Treasurer | M Exercise deriv | 2017-04-01 | 2017-04-04 | 18,750 | — | $0 | 56,250 | SEC↗ |
| SBLENDORIO GLENN | President, CFO and Treasurer | M Exercise | 2017-04-01 | 2017-04-04 | 18,750 | — | $0 | 18,960 | SEC↗ |
| Westby Keith | SVP & COO | A Award deriv | 2017-01-30 | 2017-02-01 | 60,000 | — | $0 | 60,000 | SEC↗ |
| SBLENDORIO GLENN | President, CFO & Treasurer | A Award deriv | 2017-01-30 | 2017-02-01 | 260,000 | — | $0 | 260,000 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | A Award deriv | 2017-01-30 | 2017-02-01 | 38,000 | — | $0 | 38,000 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | A Award deriv | 2017-01-30 | 2017-02-01 | 260,000 | — | $0 | 260,000 | SEC↗ |
| SBLENDORIO GLENN | EVP, COO & CFO, Treasurer | A Award deriv | 2017-01-17 | 2017-01-19 | 40,840 | — | $0 | 40,840 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | A Award deriv | 2017-01-17 | 2017-01-19 | 60,960 | — | $0 | 60,960 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | A Award deriv | 2017-01-17 | 2017-01-19 | 24,280 | — | $0 | 24,280 | SEC↗ |
| Bjarke Henric Bjorn | SVP & CCO | S Sale | 2017-01-05 | 2017-01-06 | 316 | $4.96 | $1.6K | 1,384 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2017-01-05 | 2017-01-06 | 815 | $4.96 | $4.0K | 15,813 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2017-01-05 | 2017-01-06 | 3,029 | $4.96 | $15.0K | 16,628 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2017-01-05 | 2017-01-06 | 3,785 | $4.96 | $18.8K | 7,212 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | S Sale | 2017-01-05 | 2017-01-06 | 589 | $4.96 | $2.9K | 1,311 | SEC↗ |
| Bjarke Henric Bjorn | SVP & CCO | M Exercise deriv | 2017-01-04 | 2017-01-06 | 700 | — | $0 | 2,100 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2017-01-04 | 2017-01-06 | 4,925 | — | $0 | 14,775 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2017-01-04 | 2017-01-06 | 1,325 | — | $0 | 3,975 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2017-01-04 | 2017-01-06 | 6,250 | — | $0 | 18,750 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | M Exercise deriv | 2017-01-04 | 2017-01-06 | 1,200 | — | $0 | 3,600 | SEC↗ |
| Bjarke Henric Bjorn | SVP & CCO | M Exercise | 2017-01-04 | 2017-01-06 | 700 | — | $0 | 1,700 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2017-01-04 | 2017-01-06 | 1,325 | — | $0 | 19,657 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2017-01-04 | 2017-01-06 | 4,925 | — | $0 | 18,332 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2017-01-04 | 2017-01-06 | 6,250 | — | $0 | 10,997 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | M Exercise | 2017-01-04 | 2017-01-06 | 1,200 | — | $0 | 1,900 | SEC↗ |
| WOOD BARBARA A | SVP, General Counsel,Secreta | S Sale | 2017-01-03 | 2017-01-04 | 675 | $4.90 | $3.3K | 700 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2017-01-03 | 2017-01-04 | 3,484 | $4.90 | $17.1K | 4,747 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2017-01-03 | 2017-01-04 | 2,999 | $4.90 | $14.7K | 13,407 | SEC↗ |
| WOOD BARBARA A | SVP, General Counsel,Secreta | M Exercise deriv | 2017-01-02 | 2017-01-04 | 1,375 | — | $0 | 2,750 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2017-01-02 | 2017-01-04 | 5,750 | — | $0 | 11,500 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2017-01-02 | 2017-01-04 | 4,875 | — | $0 | 9,750 | SEC↗ |
| WOOD BARBARA A | SVP, General Counsel,Secreta | M Exercise | 2017-01-02 | 2017-01-04 | 1,375 | — | $0 | 1,375 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2017-01-02 | 2017-01-04 | 5,750 | — | $0 | 8,231 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2017-01-02 | 2017-01-04 | 4,875 | — | $0 | 16,406 | SEC↗ |
| Bolte Axel | Director | S Sale | 2016-12-30 | 2017-01-23 | 6,000 | $4.83 | $29.0K | 0 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | S Sale | 2016-12-23 | 2016-12-27 | 746 | $4.92 | $3.7K | 0 | SEC↗ |
| SBLENDORIO GLENN | EVP, COO & CFO, Treasurer | S Sale | 2016-12-22 | 2016-12-23 | 1,079 | $4.85 | $5.2K | 0 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-12-15 | 2016-12-16 | 1,405,487 | $4.72 | $6.63M | 0 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-12-14 | 2016-12-16 | 2,205,000 | $4.97 | $10.96M | 1,405,487 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2016-11-01 | 2016-11-03 | 22,060 | — | $0 | 105,636 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-11-01 | 2016-11-03 | 3,820 | $36.86 | $140.8K | 2,481 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-11-01 | 2016-11-03 | 7,710 | $35.93 | $277.0K | 6,301 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-11-01 | 2016-11-03 | 10,530 | $34.93 | $367.8K | 14,011 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2016-11-01 | 2016-11-03 | 22,060 | $10.03 | $221.3K | 24,541 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2016-10-03 | 2016-10-05 | 16,210 | — | $0 | 8,334 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-10-03 | 2016-10-05 | 1,600 | $45.97 | $73.6K | 2,481 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-10-03 | 2016-10-05 | 6,632 | $44.77 | $296.9K | 4,081 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-10-03 | 2016-10-05 | 13,828 | $44.00 | $608.4K | 10,713 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2016-10-03 | 2016-10-05 | 16,210 | $10.03 | $162.6K | 24,541 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-09-29 | 2016-10-03 | 2,612 | $54.93 | $143.5K | 21,627 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-09-29 | 2016-10-03 | 2,000 | $56.90 | $113.8K | 11,531 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-09-29 | 2016-10-03 | 8,096 | $55.75 | $451.4K | 13,531 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-09-29 | 2016-10-03 | 7,292 | $54.13 | $394.7K | 24,239 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-09-01 | 2016-09-06 | 24,060 | $52.58 | $1.27M | 8,331 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-08-29 | 2016-08-31 | 20,000 | $52.80 | $1.06M | 31,531 | SEC↗ |
| SMITH IAN F | Director | A Award deriv | 2016-08-02 | 2016-08-04 | 20,000 | — | $0 | 20,000 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2016-08-01 | 2016-08-03 | 24,060 | — | $0 | 24,544 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-08-01 | 2016-08-03 | 21,255 | $64.39 | $1.37M | 35,196 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2016-08-01 | 2016-08-03 | 24,060 | $10.03 | $241.3K | 56,451 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-08-01 | 2016-08-03 | 2,805 | $65.06 | $182.5K | 32,391 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-07-29 | 2016-08-02 | 15,500 | $64.09 | $993.4K | 176,031 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-07-29 | 2016-08-02 | 4,500 | $64.62 | $290.8K | 171,531 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2016-07-01 | 2016-07-06 | 24,060 | — | $0 | 48,604 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-07-01 | 2016-07-06 | 5,300 | $51.13 | $271.0K | 51,151 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-07-01 | 2016-07-06 | 17,960 | $52.38 | $940.7K | 33,191 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2016-07-01 | 2016-07-06 | 24,060 | $10.03 | $241.3K | 56,451 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-07-01 | 2016-07-06 | 800 | $52.75 | $42.2K | 32,391 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-06-30 | 2016-07-01 | 19,146 | $50.94 | $975.3K | 194,231 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-06-30 | 2016-07-01 | 2,700 | $51.86 | $140.0K | 191,531 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2016-06-29 | 2016-07-01 | 40,000 | — | $0 | 213,377 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-06-29 | 2016-07-01 | 1,615 | $51.94 | $83.9K | 173,377 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-06-29 | 2016-07-01 | 18,385 | $51.37 | $944.4K | 174,992 | SEC↗ |
| Bolte Axel | Director | P Buy | 2016-06-03 | 2016-06-07 | 3,500 | $56.97 | $199.4K | 6,000 | SEC↗ |
| ROSS MICHAEL JAY | Director | A Award deriv | 2016-06-02 | 2016-06-03 | 7,000 | — | $0 | 7,000 | SEC↗ |
| ROSS MICHAEL JAY | Director | A Award deriv | 2016-06-02 | 2016-06-03 | 1,750 | — | $0 | 1,750 | SEC↗ |
| Redlick David E | Director | A Award deriv | 2016-06-02 | 2016-06-03 | 7,000 | — | $0 | 7,000 | SEC↗ |
| Redlick David E | Director | A Award deriv | 2016-06-02 | 2016-06-03 | 1,750 | — | $0 | 1,750 | SEC↗ |
| SBLENDORIO GLENN | EVP, COO & CFO, Treasurer | S Sale | 2016-06-02 | 2016-06-03 | 671 | $57.20 | $38.4K | 1,079 | SEC↗ |
| SBLENDORIO GLENN | EVP, COO & CFO, Treasurer | M Exercise deriv | 2016-06-01 | 2016-06-03 | 1,750 | — | $0 | 0 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2016-06-01 | 2016-06-03 | 30,060 | — | $0 | 72,664 | SEC↗ |
| ROSS MICHAEL JAY | Director | M Exercise | 2016-06-01 | 2016-06-03 | 1,750 | — | $0 | 1,750 | SEC↗ |
| SBLENDORIO GLENN | EVP, COO & CFO, Treasurer | M Exercise | 2016-06-01 | 2016-06-03 | 1,750 | — | $0 | 1,750 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-06-01 | 2016-06-03 | 25,766 | $52.59 | $1.36M | 36,685 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2016-06-01 | 2016-06-03 | 30,060 | $10.03 | $301.5K | 62,451 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-06-01 | 2016-06-03 | 4,294 | $53.44 | $229.5K | 32,391 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2016-05-31 | 2016-06-02 | 1,185 | — | $0 | 14,214 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-05-31 | 2016-06-02 | 1,674 | $52.03 | $87.1K | 211,703 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2016-05-31 | 2016-06-02 | 1,185 | $13.22 | $15.7K | 213,377 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-05-31 | 2016-06-02 | 3,709 | $53.81 | $199.6K | 193,677 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-05-31 | 2016-06-02 | 14,317 | $53.33 | $763.5K | 197,386 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-05-31 | 2016-06-02 | 300 | $54.09 | $16.2K | 193,377 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-05-24 | 2016-05-25 | 1,300,000 | $49.00 | $63.70M | 3,610,489 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2016-05-02 | 2016-05-04 | 22,060 | — | $0 | 102,724 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-05-02 | 2016-05-04 | 17,421 | $46.01 | $801.5K | 37,030 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-05-02 | 2016-05-04 | 4,639 | $46.82 | $217.2K | 32,391 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2016-05-02 | 2016-05-04 | 22,060 | $10.03 | $221.3K | 54,451 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2016-04-29 | 2016-05-03 | 1,184 | — | $0 | 15,399 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2016-04-29 | 2016-05-03 | 1,413 | — | $0 | 0 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2016-04-29 | 2016-05-03 | 1,184 | $13.22 | $15.7K | 232,192 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-04-29 | 2016-05-03 | 18,435 | $46.71 | $861.1K | 213,757 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-04-29 | 2016-05-03 | 1,565 | $47.78 | $74.8K | 212,192 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2016-04-29 | 2016-05-03 | 1,413 | $1.65 | $2.3K | 231,008 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2016-04-01 | 2016-04-05 | 0 | — | $0 | 124,784 | SEC↗ |
| SBLENDORIO GLENN | EVP, COO & CFO, Treasurer | A Award deriv | 2016-04-01 | 2016-04-05 | 75,000 | — | $0 | 75,000 | SEC↗ |
| SBLENDORIO GLENN | EVP, COO & CFO, Treasurer | A Award deriv | 2016-04-01 | 2016-04-05 | 150,000 | — | $0 | 150,000 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-04-01 | 2016-04-05 | 12,969 | $44.43 | $576.2K | 35,872 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2016-04-01 | 2016-04-05 | 22,060 | $10.03 | $221.3K | 54,451 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-04-01 | 2016-04-05 | 2,110 | $41.98 | $88.6K | 52,341 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-04-01 | 2016-04-05 | 3,500 | $43.21 | $151.2K | 48,841 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-04-01 | 2016-04-05 | 3,481 | $45.09 | $157.0K | 32,391 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2016-03-29 | 2016-03-31 | 1,185 | — | $0 | 16,583 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2016-03-29 | 2016-03-31 | 1,412 | — | $0 | 1,413 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2016-03-29 | 2016-03-31 | 1,412 | $1.65 | $2.3K | 248,410 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-03-29 | 2016-03-31 | 5,118 | $42.05 | $215.2K | 235,874 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-03-29 | 2016-03-31 | 6,279 | $43.07 | $270.4K | 229,595 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-03-29 | 2016-03-31 | 8,603 | $40.83 | $351.3K | 240,992 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2016-03-29 | 2016-03-31 | 1,185 | $13.22 | $15.7K | 249,595 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2016-03-01 | 2016-03-03 | 22,060 | — | $0 | 146,844 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2016-03-01 | 2016-03-03 | 22,060 | $10.03 | $221.3K | 54,451 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-03-01 | 2016-03-03 | 3,000 | $44.61 | $133.8K | 51,451 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-03-01 | 2016-03-03 | 16,592 | $45.53 | $755.4K | 34,859 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-03-01 | 2016-03-03 | 2,468 | $46.21 | $114.0K | 32,391 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2016-02-29 | 2016-03-02 | 3,262 | — | $0 | 17,768 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2016-02-29 | 2016-03-02 | 2,825 | — | $0 | 2,825 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2016-02-29 | 2016-03-02 | 3,262 | $13.22 | $43.1K | 266,998 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-02-29 | 2016-03-02 | 18,065 | $45.04 | $813.6K | 248,933 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-02-29 | 2016-03-02 | 1,935 | $45.92 | $88.9K | 246,998 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2016-02-29 | 2016-03-02 | 2,825 | $1.65 | $4.7K | 263,736 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-01-29 | 2016-02-02 | 8,482 | $53.92 | $457.3K | 261,011 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-01-29 | 2016-02-02 | 100 | $54.69 | $5.5K | 260,911 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-01-29 | 2016-02-02 | 11,418 | $53.33 | $608.9K | 269,493 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2016-01-28 | 2016-02-01 | 18,598 | — | $0 | 168,904 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-01-28 | 2016-02-01 | 600 | $55.03 | $33.0K | 32,991 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-01-28 | 2016-02-01 | 3,200 | $54.10 | $173.1K | 33,591 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-01-28 | 2016-02-01 | 600 | $56.29 | $33.8K | 32,391 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2016-01-28 | 2016-02-01 | 18,598 | $10.03 | $186.5K | 50,989 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-01-28 | 2016-02-01 | 14,198 | $53.35 | $757.5K | 36,791 | SEC↗ |
| GALAKATOS NICHOLAS | Director | S Sale | 2016-01-11 | 2016-01-13 | 999 | $65.45 | $65.4K | 6,685 | SEC↗ |
| GALAKATOS NICHOLAS | Director | S Sale | 2016-01-11 | 2016-01-13 | 499 | $65.33 | $32.6K | 3,945 | SEC↗ |
| GALAKATOS NICHOLAS | Director | S Sale | 2016-01-11 | 2016-01-13 | 501 | $65.45 | $32.8K | 4,444 | SEC↗ |
| GALAKATOS NICHOLAS | Director | S Sale | 2016-01-11 | 2016-01-13 | 1,001 | $66.33 | $66.4K | 5,684 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | A Award deriv | 2016-01-04 | 2016-01-06 | 25,000 | — | $0 | 25,000 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | A Award deriv | 2016-01-04 | 2016-01-06 | 95,000 | — | $0 | 95,000 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | A Award deriv | 2016-01-04 | 2016-01-06 | 19,200 | — | $0 | 19,200 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | M Exercise deriv | 2016-01-04 | 2016-01-06 | 1,000 | — | $0 | 59,000 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | A Award deriv | 2016-01-04 | 2016-01-06 | 4,800 | — | $0 | 4,800 | SEC↗ |
| Bjarke Henric Bjorn | SVP & CCO | A Award deriv | 2016-01-04 | 2016-01-06 | 2,800 | — | $0 | 2,800 | SEC↗ |
| Bjarke Henric Bjorn | SVP & CCO | A Award deriv | 2016-01-04 | 2016-01-06 | 11,300 | — | $0 | 11,300 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | A Award deriv | 2016-01-04 | 2016-01-06 | 16,300 | — | $0 | 16,300 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | A Award deriv | 2016-01-04 | 2016-01-06 | 78,700 | — | $0 | 78,700 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | A Award deriv | 2016-01-04 | 2016-01-06 | 5,300 | — | $0 | 5,300 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | A Award deriv | 2016-01-04 | 2016-01-06 | 19,700 | — | $0 | 19,700 | SEC↗ |
| Redlick David E | Director | A Award deriv | 2016-01-04 | 2016-01-06 | 20,000 | — | $0 | 20,000 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | S Sale | 2016-01-04 | 2016-01-05 | 216 | $72.93 | $15.8K | 878 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | S Sale | 2016-01-04 | 2016-01-05 | 115 | $71.93 | $8.3K | 1,094 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | S Sale | 2016-01-04 | 2016-01-05 | 21 | $74.96 | $1.6K | 746 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | S Sale | 2016-01-04 | 2016-01-05 | 111 | $74.05 | $8.2K | 767 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | S Sale | 2016-01-04 | 2016-01-05 | 166 | $71.15 | $11.8K | 1,209 | SEC↗ |
| ATIEH MICHAEL G | EVP, CFO, & CBO, Treasurer | S Sale | 2016-01-04 | 2016-01-05 | 23 | $74.05 | $1.7K | 299 | SEC↗ |
| ATIEH MICHAEL G | EVP, CFO, & CBO, Treasurer | S Sale | 2016-01-04 | 2016-01-05 | 45 | $72.93 | $3.3K | 322 | SEC↗ |
| ATIEH MICHAEL G | EVP, CFO, & CBO, Treasurer | S Sale | 2016-01-04 | 2016-01-05 | 34 | $71.15 | $2.4K | 391 | SEC↗ |
| ATIEH MICHAEL G | EVP, CFO, & CBO, Treasurer | S Sale | 2016-01-04 | 2016-01-05 | 4 | $74.96 | $300 | 295 | SEC↗ |
| ATIEH MICHAEL G | EVP, CFO, & CBO, Treasurer | S Sale | 2016-01-04 | 2016-01-05 | 24 | $71.93 | $1.7K | 367 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-01-04 | 2016-01-05 | 472 | $71.93 | $34.0K | 282,331 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-01-04 | 2016-01-05 | 677 | $71.15 | $48.2K | 282,803 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-01-04 | 2016-01-05 | 454 | $74.05 | $33.6K | 280,996 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-01-04 | 2016-01-05 | 85 | $74.96 | $6.4K | 280,911 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2016-01-04 | 2016-01-05 | 881 | $72.93 | $64.3K | 281,450 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-01-04 | 2016-01-05 | 108 | $74.96 | $8.1K | 32,391 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-01-04 | 2016-01-05 | 862 | $71.15 | $61.3K | 34,798 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-01-04 | 2016-01-05 | 600 | $71.93 | $43.2K | 34,198 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-01-04 | 2016-01-05 | 1,121 | $72.93 | $81.8K | 33,077 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2016-01-04 | 2016-01-05 | 578 | $74.05 | $42.8K | 32,499 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | S Sale | 2016-01-04 | 2016-01-06 | 1,000 | $76.37 | $76.4K | 746 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | M Exercise | 2016-01-04 | 2016-01-06 | 1,000 | $24.49 | $24.5K | 1,746 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | M Exercise deriv | 2016-01-02 | 2016-01-05 | 1,375 | — | $0 | 4,125 | SEC↗ |
| ATIEH MICHAEL G | EVP, CFO, & CBO, Treasurer | M Exercise deriv | 2016-01-02 | 2016-01-05 | 425 | — | $0 | 1,275 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2016-01-02 | 2016-01-05 | 4,875 | — | $0 | 14,625 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2016-01-02 | 2016-01-05 | 5,750 | — | $0 | 17,250 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | M Exercise | 2016-01-02 | 2016-01-05 | 1,375 | — | $0 | 1,375 | SEC↗ |
| ATIEH MICHAEL G | EVP, CFO, & CBO, Treasurer | M Exercise | 2016-01-02 | 2016-01-05 | 425 | — | $0 | 425 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2016-01-02 | 2016-01-05 | 4,875 | — | $0 | 283,480 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2016-01-02 | 2016-01-05 | 5,750 | — | $0 | 35,660 | SEC↗ |
| SBLENDORIO GLENN | Director | M Exercise deriv | 2015-12-30 | 2016-01-04 | 2,000 | — | $0 | 11,084 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise deriv | 2015-12-30 | 2016-01-04 | 18,582 | — | $0 | 187,502 | SEC↗ |
| SBLENDORIO GLENN | Director | S Sale | 2015-12-30 | 2016-01-04 | 2,000 | $80.00 | $160.0K | 0 | SEC↗ |
| SBLENDORIO GLENN | Director | M Exercise | 2015-12-30 | 2016-01-04 | 2,000 | $13.22 | $26.4K | 2,000 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | M Exercise | 2015-12-30 | 2016-01-04 | 18,582 | $10.03 | $186.4K | 48,492 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2015-12-30 | 2016-01-04 | 6,951 | $79.31 | $551.3K | 29,910 | SEC↗ |
| GUYER DAVID R | Chief Executive Officer | S Sale | 2015-12-30 | 2016-01-04 | 11,631 | $78.53 | $913.4K | 36,861 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2015-12-29 | 2015-12-31 | 1,184 | — | $0 | 21,030 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2015-12-29 | 2015-12-31 | 560 | $77.00 | $43.1K | 279,229 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2015-12-29 | 2015-12-31 | 1,184 | $13.22 | $15.7K | 279,789 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2015-12-29 | 2015-12-31 | 624 | $77.95 | $48.6K | 278,605 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2015-12-24 | 2015-12-28 | 5,530 | — | $0 | 5,650 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2015-12-24 | 2015-12-28 | 14,583 | — | $0 | 72,917 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise deriv | 2015-12-24 | 2015-12-28 | 5,923 | — | $0 | 22,214 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2015-12-24 | 2015-12-28 | 5,923 | $13.22 | $78.3K | 290,058 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2015-12-24 | 2015-12-28 | 14,583 | $31.29 | $456.3K | 304,641 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2015-12-24 | 2015-12-28 | 9,100 | $76.42 | $695.4K | 295,541 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2015-12-24 | 2015-12-28 | 14,636 | $77.32 | $1.13M | 280,905 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2015-12-24 | 2015-12-28 | 2,100 | $78.20 | $164.2K | 278,805 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | S Sale | 2015-12-24 | 2015-12-28 | 200 | $79.02 | $15.8K | 278,605 | SEC↗ |
| PATEL SAMIR CHANDRAKANT | President | M Exercise | 2015-12-24 | 2015-12-28 | 5,530 | $1.65 | $9.1K | 284,135 | SEC↗ |
| GALAKATOS NICHOLAS | Director | S Sale | 2015-12-10 | 2015-12-14 | 733 | $64.63 | $47.4K | 4,945 | SEC↗ |
| GALAKATOS NICHOLAS | Director | S Sale | 2015-12-10 | 2015-12-14 | 267 | $63.91 | $17.1K | 5,678 | SEC↗ |
| GALAKATOS NICHOLAS | Director | S Sale | 2015-12-10 | 2015-12-14 | 1,467 | $64.63 | $94.8K | 7,684 | SEC↗ |
| GALAKATOS NICHOLAS | Director | S Sale | 2015-12-10 | 2015-12-14 | 533 | $63.90 | $34.1K | 9,151 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | M Exercise deriv | 2015-12-01 | 2015-12-03 | 2,000 | — | $0 | 60,000 | SEC↗ |
| WOOD BARBARA A | SVP,General Counsel,Secretar | S Sale | 2015-12-01 | 2015-12-03 | 1,900 | $63.21 | $120.1K | 100 | SEC↗ |