ORIC

Oric Pharmaceuticals, Inc.CIK 1796280 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

—

0 trades · 0 insiders

Open-mkt sales · 90d

$2.76M

11 trades · 2 insiders

Net · 90d

$-2.76M

Insiders on file

AI insights for ORIC PRO

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AI insights for ORIC

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date

Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Piscitelli Dominic	Chief Financial Officer	82	$321.6K	$4.39M	2026-10-20
Heyman Richard A.	Director	44	$0	$768.4K	2026-10-01
You Angie	Director	8	$263.0K	$0	2026-01-02
Chacko Jacob	President and CEO	75	$3.01M	$6.50M	2026-01-02
Multani Pratik S	Chief Medical Officer	36	$0	$229.4K	2026-01-02
Dier Mardi	Director	7	$0	$0	2026-01-02
Kunkel Lori Anne	Director	17	$0	$0	2026-01-02
Hoerter Steven L.	Director	6	$0	$0	2026-01-02
COLUMN GROUP II, LP	10% Owner	16	$0	$0	2021-11-16
Svennilson Peter	Director, 10% Owner	10	$0	$0	2021-06-16
GORDON CARL L	Director, 10% Owner	23	$4.50M	$15.17M	2021-06-16
SCHELLER RICHARD H	Director	15	$0	$275.8K	2021-05-24
ORBIMED ADVISORS LLC	Director, 10% Owner	15	$4.50M	$12.46M	2021-03-30
OrbiMed Capital GP VI LLC	Director	6	$0	$2.71M	2021-03-23
LG Management, LLC	10% Owner	9	$0	$0	2020-11-04

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2026-10-20	2026-10-21	14,000	—	$0	64,500	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2026-10-20	2026-10-21	14,000	$13.53	$189.4K	69,828	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2026-10-20	2026-10-21	14,000	$4.36	$61.0K	83,828	SEC↗
Heyman Richard A.	Director	M Exercise deriv	2026-10-01	2026-10-02	3,500	—	$0	26,700	SEC↗
Heyman Richard A.	Director	S Sale	2026-10-01	2026-10-02	3,200	$12.91	$41.3K	203,472	SEC↗
Heyman Richard A.	Director	S Sale	2026-10-01	2026-10-02	3,500	$12.91	$45.2K	38,300	SEC↗
Heyman Richard A.	Director	M Exercise	2026-10-01	2026-10-02	3,500	$1.60	$5.6K	41,800	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2026-09-28	2026-09-29	13,400	—	$0	78,500	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2026-09-28	2026-09-29	13,400	$4.36	$58.4K	83,228	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2026-09-28	2026-09-29	13,400	$13.53	$181.3K	69,828	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2026-09-28	2026-09-29	13,400	—	$0	78,500	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2026-09-28	2026-09-29	13,400	$13.53	$181.3K	69,828	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2026-09-28	2026-09-29	13,400	$4.36	$58.4K	83,228	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2026-09-24	2026-09-25	600	—	$0	91,900	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2026-09-24	2026-09-25	500	$13.51	$6.8K	69,828	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2026-09-24	2026-09-25	100	$13.50	$1.4K	70,328	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2026-09-24	2026-09-25	600	$4.36	$2.6K	70,428	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2026-09-24	2026-09-25	600	—	$0	91,900	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2026-09-24	2026-09-25	500	$13.51	$6.8K	69,828	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2026-09-24	2026-09-25	100	$13.50	$1.4K	70,328	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2026-09-24	2026-09-25	600	$4.36	$2.6K	70,428	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2026-08-26	2026-08-28	52,000	—	$0	92,500	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2026-08-26	2026-08-28	25,000	—	$0	120,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2026-08-26	2026-08-28	77,000	$13.69	$1.05M	69,828	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2026-08-26	2026-08-28	25,000	$6.00	$150.0K	146,828	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2026-08-26	2026-08-28	52,000	$4.36	$226.7K	121,828	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2026-08-26	2026-08-28	25,000	—	$0	120,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2026-08-26	2026-08-28	52,000	—	$0	92,500	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2026-08-26	2026-08-28	77,000	$13.69	$1.05M	69,828	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2026-08-26	2026-08-28	25,000	$6.00	$150.0K	146,828	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2026-08-26	2026-08-28	52,000	$4.36	$226.7K	121,828	SEC↗
Heyman Richard A.	Director	M Exercise deriv	2026-07-24	2026-07-28	3,500	—	$0	30,200	SEC↗
Heyman Richard A.	Director	S Sale	2026-07-24	2026-07-28	6,100	$12.02	$73.3K	206,672	SEC↗
Heyman Richard A.	Director	S Sale	2026-07-24	2026-07-28	7,000	$12.02	$84.1K	38,300	SEC↗
Heyman Richard A.	Director	M Exercise	2026-07-24	2026-07-28	3,500	$1.60	$5.6K	45,300	SEC↗
Heyman Richard A.	Director	M Exercise deriv	2026-07-24	2026-07-28	3,500	—	$0	30,200	SEC↗
Heyman Richard A.	Director	S Sale	2026-07-24	2026-07-28	6,100	$12.02	$73.3K	206,672	SEC↗
Heyman Richard A.	Director	S Sale	2026-07-24	2026-07-28	7,000	$12.02	$84.1K	38,300	SEC↗
Heyman Richard A.	Director	M Exercise	2026-07-24	2026-07-28	3,500	$1.60	$5.6K	45,300	SEC↗
Heyman Richard A.	Director	S Sale	2026-07-06	2026-07-08	300	$12.00	$3.6K	212,772	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2026-02-24	2026-02-26	52,000	—	$0	144,500	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2026-02-24	2026-02-26	52,000	$4.36	$226.7K	120,148	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2026-02-24	2026-02-26	52,000	$13.51	$702.5K	68,148	SEC↗
Heyman Richard A.	Director	S Sale	2026-01-16	2026-01-20	3,500	$12.00	$42.0K	41,800	SEC↗
Heyman Richard A.	Director	S Sale	2026-01-16	2026-01-20	3,200	$12.00	$38.4K	213,072	SEC↗
Chacko Jacob	PRESIDENT AND CEO	A Award deriv	2026-01-02	2026-01-06	112,500	—	$0	112,500	SEC↗
Chacko Jacob	PRESIDENT AND CEO	A Award deriv	2026-01-02	2026-01-06	675,000	—	$0	675,000	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2026-01-02	2026-01-06	35,500	—	$0	35,500	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2026-01-02	2026-01-06	214,000	—	$0	214,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2026-01-02	2026-01-06	34,500	—	$0	34,500	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2026-01-02	2026-01-06	206,500	—	$0	206,500	SEC↗
Dier Mardi	Director	A Award deriv	2026-01-02	2026-01-06	40,000	—	$0	40,000	SEC↗
Heyman Richard A.	Director	A Award deriv	2026-01-02	2026-01-06	40,000	—	$0	40,000	SEC↗
Hoerter Steven L.	Director	A Award deriv	2026-01-02	2026-01-06	40,000	—	$0	40,000	SEC↗
Kunkel Lori Anne	Director	A Award deriv	2026-01-02	2026-01-06	40,000	—	$0	40,000	SEC↗
You Angie	Director	A Award deriv	2026-01-02	2026-01-06	40,000	—	$0	40,000	SEC↗
Chacko Jacob	PRESIDENT AND CEO	S Sale	2025-12-16	2025-12-17	33,374	$9.06	$302.4K	581,711	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2025-12-16	2025-12-17	10,720	$9.06	$97.1K	68,148	SEC↗
Multani Pratik S	Chief Medical Officer	S Sale	2025-12-16	2025-12-17	10,720	$9.06	$97.1K	68,149	SEC↗
Chacko Jacob	PRESIDENT AND CEO	M Exercise deriv	2025-12-15	2025-12-17	28,333	—	$0	28,334	SEC↗
Chacko Jacob	PRESIDENT AND CEO	M Exercise deriv	2025-12-15	2025-12-17	22,000	—	$0	0	SEC↗
Chacko Jacob	PRESIDENT AND CEO	M Exercise deriv	2025-12-15	2025-12-17	33,333	—	$0	66,667	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2025-12-15	2025-12-17	10,000	—	$0	10,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2025-12-15	2025-12-17	8,000	—	$0	0	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2025-12-15	2025-12-17	11,333	—	$0	22,667	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise deriv	2025-12-15	2025-12-17	11,333	—	$0	22,667	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise deriv	2025-12-15	2025-12-17	8,000	—	$0	0	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise deriv	2025-12-15	2025-12-17	10,000	—	$0	10,000	SEC↗
Chacko Jacob	PRESIDENT AND CEO	M Exercise	2025-12-15	2025-12-17	83,666	—	$0	615,085	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2025-12-15	2025-12-17	29,333	—	$0	78,868	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise	2025-12-15	2025-12-17	29,333	—	$0	78,869	SEC↗
Kunkel Lori Anne	Director	M Exercise deriv	2025-12-08	2025-12-09	10,000	—	$0	15,600	SEC↗
Kunkel Lori Anne	Director	M Exercise	2025-12-08	2025-12-09	10,000	$7.90	$79.0K	84,200	SEC↗
Kunkel Lori Anne	Director	M Exercise deriv	2025-12-04	2025-12-05	5,534	—	$0	0	SEC↗
Kunkel Lori Anne	Director	M Exercise	2025-12-04	2025-12-05	5,534	$3.75	$20.8K	74,200	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2025-10-06	2025-10-08	11,000	—	$0	196,500	SEC↗
Chacko Jacob	PRESIDENT AND CEO	S Sale	2025-10-06	2025-10-08	37,461	$12.32	$461.5K	531,419	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2025-10-06	2025-10-08	11,000	$4.36	$48.0K	59,317	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2025-10-06	2025-10-08	11,000	$14.52	$159.7K	48,317	SEC↗
Heyman Richard A.	Director	M Exercise deriv	2025-10-03	2025-10-03	18,125	—	$0	0	SEC↗
Heyman Richard A.	Director	M Exercise deriv	2025-10-03	2025-10-03	13,228	—	$0	33,700	SEC↗
Heyman Richard A.	Director	M Exercise deriv	2025-10-03	2025-10-03	1,447	—	$0	52,253	SEC↗
Heyman Richard A.	Director	M Exercise	2025-10-03	2025-10-03	1,447	$3.75	$5.4K	45,300	SEC↗
Heyman Richard A.	Director	M Exercise	2025-10-03	2025-10-03	31,353	$1.60	$50.2K	43,853	SEC↗
Chacko Jacob	PRESIDENT AND CEO	S Sale	2025-10-01	2025-10-02	53,001	$12.05	$638.7K	568,880	SEC↗
Chacko Jacob	PRESIDENT AND CEO	S Sale	2025-09-30	2025-10-02	34,538	$12.01	$414.8K	621,881	SEC↗
Chacko Jacob	PRESIDENT AND CEO	S Sale	2025-09-22	2025-09-24	125,000	$10.80	$1.35M	656,419	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2025-07-01	2025-07-02	20,000	$10.05	$201.0K	48,317	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2025-06-24	2025-06-24	32,466	$10.50	$340.9K	68,317	SEC↗
You Angie	Director	P Buy	2025-06-23	2025-06-23	1,403	$9.43	$13.2K	28,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2025-06-23	2025-06-24	450	$10.01	$4.5K	100,783	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2025-06-23	2025-06-24	584	$10.00	$5.8K	101,233	SEC↗
You Angie	Director	P Buy	2025-06-20	2025-06-23	26,597	$9.39	$249.7K	26,597	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2025-06-12	2025-06-13	300	$10.00	$3.0K	101,817	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2025-06-11	2025-06-11	1,276	$10.00	$12.8K	103,817	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2025-06-11	2025-06-11	1,700	$10.01	$17.0K	102,117	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2025-06-10	2025-06-11	324	$10.00	$3.2K	105,093	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2025-06-09	2025-06-09	300	$10.00	$3.0K	103,864	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2025-06-06	2025-06-09	2,600	$10.01	$26.0K	104,164	SEC↗
Kunkel Lori Anne	Director	M Exercise deriv	2025-03-03	2025-03-04	20,500	—	$0	0	SEC↗
Kunkel Lori Anne	Director	M Exercise deriv	2025-03-03	2025-03-04	27,666	—	$0	5,534	SEC↗
Kunkel Lori Anne	Director	M Exercise	2025-03-03	2025-03-04	27,666	$3.75	$103.7K	48,166	SEC↗
Kunkel Lori Anne	Director	M Exercise	2025-03-03	2025-03-04	20,500	$6.33	$129.8K	68,666	SEC↗
Chacko Jacob	PRESIDENT AND CEO	A Award deriv	2025-01-02	2025-01-03	600,000	—	$0	600,000	SEC↗
Chacko Jacob	PRESIDENT AND CEO	A Award deriv	2025-01-02	2025-01-03	100,000	—	$0	100,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2025-01-02	2025-01-03	34,000	—	$0	34,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2025-01-02	2025-01-03	202,500	—	$0	202,500	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2025-01-02	2025-01-03	202,500	—	$0	202,500	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2025-01-02	2025-01-03	34,000	—	$0	34,000	SEC↗
Dier Mardi	Director	A Award deriv	2025-01-02	2025-01-06	35,000	—	$0	35,000	SEC↗
Heyman Richard A.	Director	A Award deriv	2025-01-02	2025-01-06	35,000	—	$0	35,000	SEC↗
Hoerter Steven L.	Director	A Award deriv	2025-01-02	2025-01-06	35,000	—	$0	35,000	SEC↗
Kunkel Lori Anne	Director	A Award deriv	2025-01-02	2025-01-06	35,000	—	$0	35,000	SEC↗
You Angie	Director	A Award deriv	2025-01-02	2025-01-06	35,000	—	$0	35,000	SEC↗
Chacko Jacob	PRESIDENT AND CEO	S Sale	2024-12-16	2024-12-17	24,660	$8.28	$204.2K	778,648	SEC↗
Multani Pratik S	Chief Medical Officer	S Sale	2024-12-16	2024-12-17	8,850	$8.28	$73.3K	46,765	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2024-12-16	2024-12-17	8,851	$8.28	$73.3K	106,764	SEC↗
Chacko Jacob	PRESIDENT AND CEO	M Exercise deriv	2024-12-15	2024-12-17	22,000	—	$0	22,000	SEC↗
Chacko Jacob	PRESIDENT AND CEO	M Exercise deriv	2024-12-15	2024-12-17	28,333	—	$0	56,667	SEC↗
Chacko Jacob	PRESIDENT AND CEO	M Exercise deriv	2024-12-15	2024-12-17	16,667	—	$0	0	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise deriv	2024-12-15	2024-12-17	10,000	—	$0	20,000	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise deriv	2024-12-15	2024-12-17	8,000	—	$0	8,000	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise deriv	2024-12-15	2024-12-17	6,042	—	$0	0	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2024-12-15	2024-12-17	10,000	—	$0	20,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2024-12-15	2024-12-17	8,000	—	$0	8,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2024-12-15	2024-12-17	6,042	—	$0	0	SEC↗
Chacko Jacob	PRESIDENT AND CEO	M Exercise	2024-12-15	2024-12-17	67,000	—	$0	803,308	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise	2024-12-15	2024-12-17	24,042	—	$0	55,615	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2024-12-15	2024-12-17	24,042	—	$0	115,615	SEC↗
Heyman Richard A.	Director	A Award deriv	2024-06-12	2024-06-14	25,600	—	$0	25,600	SEC↗
Dier Mardi	Director	A Award deriv	2024-06-12	2024-06-14	25,600	—	$0	25,600	SEC↗
Hoerter Steven L.	Director	A Award deriv	2024-06-12	2024-06-14	25,600	—	$0	25,600	SEC↗
Kunkel Lori Anne	Director	A Award deriv	2024-06-12	2024-06-14	25,600	—	$0	25,600	SEC↗
You Angie	Director	A Award deriv	2024-06-12	2024-06-14	25,600	—	$0	25,600	SEC↗
Kunkel Lori Anne	Director	M Exercise deriv	2024-06-03	2024-06-04	20,500	—	$0	33,200	SEC↗
Kunkel Lori Anne	Director	M Exercise	2024-06-03	2024-06-04	20,500	$3.75	$76.9K	20,500	SEC↗
Chacko Jacob	PRESIDENT AND CEO	S Sale	2024-03-06	2024-03-08	40,000	$16.21	$648.4K	728,544	SEC↗
Chacko Jacob	PRESIDENT AND CEO	S Sale	2024-02-07	2024-02-08	26,042	$12.30	$320.3K	768,544	SEC↗
Chacko Jacob	PRESIDENT AND CEO	S Sale	2024-02-06	2024-02-08	13,958	$12.12	$169.2K	794,586	SEC↗
Chacko Jacob	President and CEO	A Award deriv	2024-01-02	2024-01-03	85,000	—	$0	85,000	SEC↗
Chacko Jacob	President and CEO	A Award deriv	2024-01-02	2024-01-03	510,000	—	$0	510,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2024-01-02	2024-01-03	30,000	—	$0	30,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2024-01-02	2024-01-03	180,000	—	$0	180,000	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2024-01-02	2024-01-03	30,000	—	$0	30,000	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2024-01-02	2024-01-03	180,000	—	$0	180,000	SEC↗
Chacko Jacob	President and CEO	M Exercise deriv	2023-12-15	2023-12-19	16,667	—	$0	16,667	SEC↗
Chacko Jacob	President and CEO	M Exercise deriv	2023-12-15	2023-12-19	22,000	—	$0	44,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2023-12-15	2023-12-19	6,042	—	$0	6,042	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2023-12-15	2023-12-19	8,000	—	$0	16,000	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise deriv	2023-12-15	2023-12-19	8,000	—	$0	16,000	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise deriv	2023-12-15	2023-12-19	6,042	—	$0	6,042	SEC↗
Chacko Jacob	President and CEO	S Sale	2023-12-15	2023-12-19	14,539	$8.58	$124.7K	808,544	SEC↗
Chacko Jacob	President and CEO	M Exercise	2023-12-15	2023-12-19	38,667	—	$0	823,083	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2023-12-15	2023-12-19	5,282	$8.58	$45.3K	83,809	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2023-12-15	2023-12-19	14,042	—	$0	89,091	SEC↗
Multani Pratik S	Chief Medical Officer	S Sale	2023-12-15	2023-12-19	5,282	$8.59	$45.4K	23,809	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise	2023-12-15	2023-12-19	14,042	—	$0	29,091	SEC↗
Chacko Jacob	President and CEO	S Sale	2023-07-11	2023-07-11	5,156	$8.01	$41.3K	780,652	SEC↗
Chacko Jacob	President and CEO	S Sale	2023-07-10	2023-07-11	10,508	$8.01	$84.2K	785,808	SEC↗
Chacko Jacob	President and CEO	S Sale	2023-07-05	2023-07-07	4,336	$8.01	$34.7K	796,316	SEC↗
Chacko Jacob	President and CEO	S Sale	2023-06-26	2023-06-28	20,000	$8.03	$160.6K	800,652	SEC↗
Dier Mardi	Director	A Award deriv	2023-06-14	2023-06-15	20,500	—	$0	20,500	SEC↗
Heyman Richard A.	Director	A Award deriv	2023-06-14	2023-06-15	20,500	—	$0	20,500	SEC↗
Hoerter Steven L.	Director	A Award deriv	2023-06-14	2023-06-15	20,500	—	$0	20,500	SEC↗
Kunkel Lori Anne	Director	A Award deriv	2023-06-14	2023-06-15	20,500	—	$0	20,500	SEC↗
You Angie	Director	A Award deriv	2023-06-14	2023-06-15	20,500	—	$0	20,500	SEC↗
Chacko Jacob	President and CEO	A Award deriv	2023-02-01	2023-02-02	66,000	—	$0	66,000	SEC↗
Chacko Jacob	President and CEO	A Award deriv	2023-02-01	2023-02-02	400,000	—	$0	400,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2023-02-01	2023-02-02	24,000	—	$0	24,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2023-02-01	2023-02-02	145,000	—	$0	145,000	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2023-02-01	2023-02-02	145,000	—	$0	145,000	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2023-02-01	2023-02-02	24,000	—	$0	24,000	SEC↗
Chacko Jacob	President and CEO	S Sale	2022-12-15	2023-02-17	6,137	$3.07	$18.8K	816,652	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2022-12-15	2023-02-17	2,227	$3.08	$6.9K	67,285	SEC↗
Multani Pratik S	Chief Medical Officer	S Sale	2022-12-15	2023-02-17	2,227	$3.07	$6.8K	7,285	SEC↗
Chacko Jacob	President and CEO	M Exercise deriv	2022-12-15	2022-12-16	16,666	—	$0	33,334	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise deriv	2022-12-15	2022-12-16	6,041	—	$0	12,084	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise deriv	2022-12-15	2022-12-16	6,041	—	$0	12,084	SEC↗
Chacko Jacob	President and CEO	M Exercise	2022-12-15	2022-12-16	16,666	—	$0	822,789	SEC↗
Chacko Jacob	President and CEO	S Sale	2022-12-15	2022-12-16	5,764	$3.25	$18.7K	817,025	SEC↗
Piscitelli Dominic	Chief Financial Officer	M Exercise	2022-12-15	2022-12-16	6,041	—	$0	69,512	SEC↗
Piscitelli Dominic	Chief Financial Officer	S Sale	2022-12-15	2022-12-16	2,089	$3.25	$6.8K	67,423	SEC↗
Multani Pratik S	Chief Medical Officer	M Exercise	2022-12-15	2022-12-16	6,041	—	$0	9,512	SEC↗
Multani Pratik S	Chief Medical Officer	S Sale	2022-12-15	2022-12-16	2,089	$3.25	$6.8K	7,423	SEC↗
Chacko Jacob	President and CEO	A Award deriv	2022-07-20	2022-07-21	300,000	—	$0	300,000	SEC↗
Chacko Jacob	President and CEO	A Award deriv	2022-07-20	2022-07-21	280,000	—	$0	280,000	SEC↗
Chacko Jacob	President and CEO	D To issuer deriv	2022-07-20	2022-07-21	280,000	—	$0	0	SEC↗
Chacko Jacob	President and CEO	A Award deriv	2022-07-20	2022-07-21	437,500	—	$0	437,500	SEC↗
Chacko Jacob	President and CEO	D To issuer deriv	2022-07-20	2022-07-21	300,000	—	$0	0	SEC↗
Chacko Jacob	President and CEO	D To issuer deriv	2022-07-20	2022-07-21	437,500	—	$0	0	SEC↗
Piscitelli Dominic	Chief Financial Officer	D To issuer deriv	2022-07-20	2022-07-21	207,500	—	$0	0	SEC↗
Piscitelli Dominic	Chief Financial Officer	D To issuer deriv	2022-07-20	2022-07-21	86,250	—	$0	0	SEC↗
Piscitelli Dominic	Chief Financial Officer	D To issuer deriv	2022-07-20	2022-07-21	90,000	—	$0	0	SEC↗
Piscitelli Dominic	Chief Financial Officer	D To issuer deriv	2022-07-20	2022-07-21	108,750	—	$0	0	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2022-07-20	2022-07-21	207,500	—	$0	207,500	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2022-07-20	2022-07-21	86,250	—	$0	86,250	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2022-07-20	2022-07-21	90,000	—	$0	90,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2022-07-20	2022-07-21	108,750	—	$0	108,750	SEC↗
Multani Pratik S	Chief Medical Officer	D To issuer deriv	2022-07-20	2022-07-21	90,000	—	$0	0	SEC↗
Multani Pratik S	Chief Medical Officer	D To issuer deriv	2022-07-20	2022-07-21	147,500	—	$0	0	SEC↗
Multani Pratik S	Chief Medical Officer	D To issuer deriv	2022-07-20	2022-07-21	108,750	—	$0	0	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2022-07-20	2022-07-21	147,500	—	$0	147,500	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2022-07-20	2022-07-21	90,000	—	$0	90,000	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2022-07-20	2022-07-21	108,750	—	$0	108,750	SEC↗
Dier Mardi	Director	A Award deriv	2022-06-17	2022-06-17	53,700	—	$0	53,700	SEC↗
Hoerter Steven L.	Director	A Award deriv	2022-06-17	2022-06-17	50,283	—	$0	50,283	SEC↗
Heyman Richard A.	Director	A Award deriv	2022-06-17	2022-06-17	53,700	—	$0	53,700	SEC↗
Kunkel Lori Anne	Director	A Award deriv	2022-06-17	2022-06-17	53,700	—	$0	53,700	SEC↗
You Angie	Director	A Award deriv	2022-06-17	2022-06-17	45,158	—	$0	45,158	SEC↗
Chacko Jacob	President and CEO	P Buy	2022-05-13	2022-05-13	76,072	$2.82	$214.5K	802,652	SEC↗
Chacko Jacob	President and CEO	P Buy	2022-05-12	2022-05-13	69,354	$2.75	$190.7K	726,580	SEC↗
Chacko Jacob	President and CEO	P Buy	2022-05-11	2022-05-13	304,574	$2.90	$883.3K	657,226	SEC↗
Piscitelli Dominic	Chief Financial Officer	P Buy	2022-03-31	2022-03-31	60,000	$5.36	$321.6K	60,000	SEC↗
Chacko Jacob	President and CEO	P Buy	2022-03-25	2022-03-25	50,000	$4.54	$227.0K	352,652	SEC↗
Chacko Jacob	President and CEO	P Buy	2022-03-24	2022-03-25	42,873	$5.03	$215.7K	302,652	SEC↗
Chacko Jacob	President and CEO	P Buy	2022-03-23	2022-03-25	257,127	$4.98	$1.28M	259,779	SEC↗
Chacko Jacob	President and CEO	A Award deriv	2022-02-01	2022-02-02	50,000	—	$0	50,000	SEC↗
Chacko Jacob	President and CEO	A Award deriv	2022-02-01	2022-02-02	300,000	—	$0	300,000	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2022-02-01	2022-02-02	108,750	—	$0	108,750	SEC↗
Piscitelli Dominic	Chief Financial Officer	A Award deriv	2022-02-01	2022-02-02	18,125	—	$0	18,125	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2022-02-01	2022-02-02	18,125	—	$0	18,125	SEC↗
Multani Pratik S	Chief Medical Officer	A Award deriv	2022-02-01	2022-02-02	108,750	—	$0	108,750	SEC↗
COLUMN GROUP II, LP	10% Owner	J Other	2021-11-16	2021-11-16	1,200,000	—	$0	3,568,181	SEC↗
COLUMN GROUP II, LP	10% Owner	J Other	2021-11-16	2021-11-16	287,702	—	$0	287,702	SEC↗
COLUMN GROUP II, LP	10% Owner	J Other	2021-11-16	2021-11-16	287,702	—	$0	0	SEC↗
COLUMN GROUP II, LP	10% Owner	J Other	2021-11-16	2021-11-16	86,716	—	$0	86,716	SEC↗
COLUMN GROUP II, LP	10% Owner	J Other	2021-11-16	2021-11-16	74	—	$0	74	SEC↗
COLUMN GROUP II, LP	10% Owner	J Other	2021-11-16	2021-11-16	86,716	—	$0	103,341	SEC↗
COLUMN GROUP II, LP	10% Owner	M Exercise deriv	2021-11-12	2021-11-16	16,625	—	$0	0	SEC↗
COLUMN GROUP II, LP	10% Owner	M Exercise	2021-11-12	2021-11-16	16,625	$16.00	$266.0K	16,625	SEC↗
You Angie	Director	A Award deriv	2021-11-09	2021-11-10	33,250	—	$0	33,250	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-09-15	2021-09-16	3,736	$25.06	$93.6K	2,652	SEC↗
Heyman Richard A.	Director	S Sale	2021-09-15	2021-09-16	682	$25.03	$17.1K	216,272	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-09-14	2021-09-16	4,420	$25.05	$110.7K	6,388	SEC↗
Heyman Richard A.	Director	S Sale	2021-09-14	2021-09-16	706	$25.05	$17.7K	216,954	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-09-13	2021-09-14	2,801	$25.02	$70.1K	10,808	SEC↗
Heyman Richard A.	Director	S Sale	2021-09-13	2021-09-14	601	$25.01	$15.0K	217,660	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-09-10	2021-09-14	2,942	$25.08	$73.8K	13,609	SEC↗
Heyman Richard A.	Director	S Sale	2021-09-10	2021-09-14	479	$25.10	$12.0K	218,261	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-09-08	2021-09-09	200	$25.04	$5.0K	16,551	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-09-07	2021-09-09	5,981	$25.11	$150.2K	16,751	SEC↗
Heyman Richard A.	Director	S Sale	2021-09-07	2021-09-09	1,086	$25.11	$27.3K	218,740	SEC↗
Hoerter Steven L.	Director	A Award deriv	2021-08-13	2021-08-16	33,250	—	$0	33,250	SEC↗
Dier Mardi	Director	A Award deriv	2021-06-16	2021-06-17	16,625	—	$0	16,625	SEC↗
GORDON CARL L	Director, 10% Owner	A Award deriv	2021-06-16	2021-06-17	16,625	—	$0	16,625	SEC↗
Heyman Richard A.	Director	A Award deriv	2021-06-16	2021-06-17	16,625	—	$0	16,625	SEC↗
Kunkel Lori Anne	Director	A Award deriv	2021-06-16	2021-06-17	16,625	—	$0	16,625	SEC↗
Svennilson Peter	Director, 10% Owner	A Award deriv	2021-06-16	2021-06-17	16,625	—	$0	16,625	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-05-27	2021-05-28	400	$25.07	$10.0K	22,732	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-05-24	2021-05-24	12	$25.00	$300	23,132	SEC↗
SCHELLER RICHARD H	Director	S Sale	2021-05-24	2021-05-24	100	$25.00	$2.5K	39,092	SEC↗
Heyman Richard A.	Director	S Sale	2021-05-24	2021-05-24	100	$25.00	$2.5K	219,826	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-05-21	2021-05-24	4,790	$25.20	$120.7K	23,144	SEC↗
SCHELLER RICHARD H	Director	S Sale	2021-05-21	2021-05-24	1,231	$25.19	$31.0K	39,192	SEC↗
Heyman Richard A.	Director	S Sale	2021-05-21	2021-05-24	600	$25.25	$15.2K	219,926	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-05-20	2021-05-24	2,468	$25.07	$61.9K	27,934	SEC↗
SCHELLER RICHARD H	Director	S Sale	2021-05-20	2021-05-24	659	$25.08	$16.5K	40,423	SEC↗
Heyman Richard A.	Director	S Sale	2021-05-20	2021-05-24	700	$25.08	$17.6K	220,526	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-05-18	2021-05-18	11,132	$25.37	$282.4K	30,602	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-05-18	2021-05-18	200	$26.03	$5.2K	30,402	SEC↗
SCHELLER RICHARD H	Director	S Sale	2021-05-18	2021-05-18	2,800	$25.34	$71.0K	41,082	SEC↗
Heyman Richard A.	Director	S Sale	2021-05-18	2021-05-18	2,161	$25.32	$54.7K	221,226	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-05-17	2021-05-18	2,550	$25.05	$63.9K	41,734	SEC↗
SCHELLER RICHARD H	Director	S Sale	2021-05-17	2021-05-18	500	$25.06	$12.5K	43,882	SEC↗
Heyman Richard A.	Director	S Sale	2021-05-17	2021-05-18	498	$25.07	$12.5K	223,387	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-05-14	2021-05-18	13,896	$25.36	$352.4K	44,284	SEC↗
SCHELLER RICHARD H	Director	S Sale	2021-05-14	2021-05-18	4,615	$25.38	$117.1K	44,382	SEC↗
Heyman Richard A.	Director	S Sale	2021-05-14	2021-05-18	3,215	$25.31	$81.4K	223,885	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-05-13	2021-05-13	730	$25.04	$18.3K	58,180	SEC↗
SCHELLER RICHARD H	Director	S Sale	2021-05-13	2021-05-13	100	$25.00	$2.5K	48,997	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-05-12	2021-05-13	400	$25.02	$10.0K	58,910	SEC↗
SCHELLER RICHARD H	Director	S Sale	2021-05-12	2021-05-13	103	$25.00	$2.6K	49,097	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-05-11	2021-05-13	1,090	$25.22	$27.5K	59,310	SEC↗
SCHELLER RICHARD H	Director	S Sale	2021-05-11	2021-05-13	300	$25.16	$7.5K	49,200	SEC↗
Heyman Richard A.	Director	S Sale	2021-05-11	2021-05-13	100	$25.11	$2.5K	227,100	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-04-30	2021-04-30	600	$25.24	$15.1K	60,400	SEC↗
SCHELLER RICHARD H	Director	S Sale	2021-04-30	2021-04-30	100	$25.19	$2.5K	49,500	SEC↗
Heyman Richard A.	Director	S Sale	2021-04-30	2021-04-30	100	$25.26	$2.5K	227,200	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-04-28	2021-04-30	700	$25.06	$17.5K	61,000	SEC↗
SCHELLER RICHARD H	Director	S Sale	2021-04-28	2021-04-30	200	$25.11	$5.0K	49,600	SEC↗
Heyman Richard A.	Director	S Sale	2021-04-28	2021-04-30	100	$25.08	$2.5K	227,300	SEC↗
Chacko Jacob	President and CEO	S Sale	2021-04-01	2021-04-05	800	$25.09	$20.1K	61,700	SEC↗
Heyman Richard A.	Director	S Sale	2021-04-01	2021-04-05	100	$25.00	$2.5K	227,400	SEC↗
SCHELLER RICHARD H	Director	S Sale	2021-04-01	2021-04-05	200	$25.00	$5.0K	49,800	SEC↗
ORBIMED ADVISORS LLC	Director	S Sale	2021-03-30	2021-03-31	27,869	$23.93	$666.9K	2,212,571	SEC↗
GORDON CARL L	Director	S Sale	2021-03-30	2021-03-31	27,869	$23.93	$666.9K	2,212,571	SEC↗
ORBIMED ADVISORS LLC	Director	S Sale	2021-03-29	2021-03-31	75,555	$23.31	$1.76M	2,240,440	SEC↗
GORDON CARL L	Director	S Sale	2021-03-29	2021-03-31	75,555	$23.31	$1.76M	2,240,440	SEC↗
GORDON CARL L	Director	S Sale	2021-03-26	2021-03-26	27,816	$23.88	$664.2K	2,315,995	SEC↗
ORBIMED ADVISORS LLC	Director	S Sale	2021-03-26	2021-03-26	27,816	$23.88	$664.2K	2,315,995	SEC↗
GORDON CARL L	Director	S Sale	2021-03-25	2021-03-26	51,523	$24.70	$1.27M	2,343,811	SEC↗
ORBIMED ADVISORS LLC	Director	S Sale	2021-03-25	2021-03-26	51,523	$24.70	$1.27M	2,343,811	SEC↗
GORDON CARL L	Director	S Sale	2021-03-24	2021-03-26	32,959	$24.80	$817.4K	2,395,334	SEC↗
ORBIMED ADVISORS LLC	Director	S Sale	2021-03-24	2021-03-26	32,959	$24.80	$817.4K	2,395,334	SEC↗
OrbiMed Capital GP VI LLC	Director	S Sale	2021-03-23	2021-03-23	3,992	$24.32	$97.1K	2,428,293	SEC↗
GORDON CARL L	Director	S Sale	2021-03-23	2021-03-23	3,992	$24.32	$97.1K	2,428,293	SEC↗
OrbiMed Capital GP VI LLC	Director	S Sale	2021-03-22	2021-03-23	7,673	$26.47	$203.1K	2,432,285	SEC↗
GORDON CARL L	Director	S Sale	2021-03-22	2021-03-23	7,673	$26.47	$203.1K	2,432,285	SEC↗
OrbiMed Capital GP VI LLC	Director	S Sale	2021-03-19	2021-03-23	21,275	$26.47	$563.1K	2,439,958	SEC↗
GORDON CARL L	Director	S Sale	2021-03-19	2021-03-23	21,275	$26.47	$563.1K	2,439,958	SEC↗