Open-mkt buys · 90d
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0 trades · 0 insiders
Open-mkt sales · 90d
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0 trades · 0 insiders
Net · 90d
$0
Insiders on file
28
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| GERAGHTY JAMES A | Director | 13 | $105.7K | $0 | 2024-12-12 |
| KIRITSY CHRISTOPHER P | Director | 15 | $34.0K | $0 | 2024-12-02 |
| ADAR1 Capital Management, LLC | 10% Owner | 3 | $92.3K | $0 | 2024-08-12 |
| Said Maya R. | Director | 7 | $0 | $0 | 2023-06-21 |
| Barbier Ann | Director | 7 | $0 | $0 | 2023-06-21 |
| Richman Michael | Director | 28 | $0 | $0 | 2023-06-21 |
| Kiener Peter A | Director | 7 | $0 | $0 | 2023-06-21 |
| Sherman Matthew L | Director | 7 | $0 | $0 | 2023-06-21 |
| Mousa Ahmed | Chief Business Officer | 2 | $0 | $0 | 2023-02-24 |
| Olwill Shane | Chief Development Officer | 6 | $0 | $196.4K | 2023-02-24 |
| Kaufmann Hitto | SVP, Chief Scientific Officer | 5 | $0 | $0 | 2023-02-24 |
| Bures Thomas | Vice President, Finance | 4 | $0 | $0 | 2023-02-24 |
| Yoder Stephen S. | President and CEO | 9 | $10.1K | $0 | 2023-02-24 |
| Demuth Tim | Chief Medical Officer | 3 | $10.3K | $0 | 2022-05-13 |
| Aquilo Capital Management, LLC | 10% Owner | 1 | $0 | $5.61M | 2020-07-21 |
| BIZZARI JEAN-PIERRE | Director | 5 | $0 | $0 | 2020-01-25 |
| BVF Partners OS Ltd. | Other | 3 | $0 | $225.0K | 2019-09-06 |
| Reine Allan | See Remarks | 6 | $313.4K | $0 | 2019-02-26 |
| Matis Louis | See Remarks | 6 | $17.0K | $0 | 2019-02-26 |
| BIOTECHNOLOGY VALUE FUND L P | Other | 6 | $0 | $0 | 2019-01-30 |
| Prelack Steven | Director | 4 | $0 | $0 | 2019-01-25 |
| ORBIMED ADVISORS LLC | 10% Owner | 2 | $0 | $6.35M | 2018-04-30 |
| OrbiMed Capital GP III LLC | 10% Owner | 64 | $0 | $912.4K | 2018-02-13 |
| ADAMS JULIAN | Director | 3 | $0 | $0 | 2018-01-25 |
| ISALY SAMUEL D | Director, 10% Owner | 4 | $1.38M | $12.57M | 2018-01-03 |
| Khuong Chau Quang | Director, 10% Owner | 14 | $1.38M | $0 | 2017-10-25 |
| Knopf Claude | Chief Business Officer | 1 | $0 | $0 | 2016-11-28 |
| DEPTULA-HICKS DARLENE M | Sr. Vice President and CFO | 2 | $8.3K | $0 | 2016-06-13 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| GERAGHTY JAMES A | Director | D To issuer | 2024-12-12 | 2024-12-12 | 1 | $0.01 | $0 | 0 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | A Award deriv | 2024-12-02 | 2024-12-09 | 500 | — | $0 | 500 | SEC↗ |
| ADAR1 Capital Management, LLC | 10% Owner | P Buy | 2024-08-12 | 2024-08-12 | 2,243 | $15.88 | $35.6K | 129,574 | SEC↗ |
| ADAR1 Capital Management, LLC | 10% Owner | P Buy | 2024-08-12 | 2024-08-12 | 757 | $15.88 | $12.0K | 15,067 | SEC↗ |
| ADAR1 Capital Management, LLC | 10% Owner | P Buy | 2024-08-09 | 2024-08-12 | 3,000 | $14.89 | $44.7K | 127,331 | SEC↗ |
| GERAGHTY JAMES A | Director | P Buy | 2024-08-07 | 2024-10-28 | 1 | $1.00 | $1 | 1 | SEC↗ |
| Sherman Matthew L | Director | A Award deriv | 2023-06-21 | 2023-06-23 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Said Maya R. | Director | A Award deriv | 2023-06-21 | 2023-06-23 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2023-06-21 | 2023-06-23 | 40,000 | — | $0 | 40,000 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | A Award deriv | 2023-06-21 | 2023-06-23 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Kiener Peter A | Director | A Award deriv | 2023-06-21 | 2023-06-23 | 40,000 | — | $0 | 40,000 | SEC↗ |
| GERAGHTY JAMES A | Director | A Award deriv | 2023-06-21 | 2023-06-23 | 45,000 | — | $0 | 45,000 | SEC↗ |
| Barbier Ann | Director | A Award deriv | 2023-06-21 | 2023-06-23 | 40,000 | — | $0 | 40,000 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | P Buy | 2023-05-25 | 2023-05-30 | 10,000 | $0.85 | $8.5K | 20,000 | SEC↗ |
| Yoder Stephen S. | Chief Executive Officer | A Award deriv | 2023-02-24 | 2023-02-28 | 634,021 | — | $0 | 634,021 | SEC↗ |
| Olwill Shane | Chief Development Officer | A Award deriv | 2023-02-24 | 2023-02-28 | 249,080 | — | $0 | 249,080 | SEC↗ |
| Mousa Ahmed | Chief Business Officer | A Award deriv | 2023-02-24 | 2023-02-28 | 249,080 | — | $0 | 249,080 | SEC↗ |
| Kaufmann Hitto | Chief Scientific Officer | A Award deriv | 2023-02-24 | 2023-02-28 | 249,080 | — | $0 | 249,080 | SEC↗ |
| Bures Thomas | Chief Financial Officer | A Award deriv | 2023-02-24 | 2023-02-28 | 249,080 | — | $0 | 249,080 | SEC↗ |
| Sherman Matthew L | Director | A Award deriv | 2022-06-22 | 2022-06-24 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2022-06-22 | 2022-06-24 | 40,000 | — | $0 | 40,000 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | A Award deriv | 2022-06-22 | 2022-06-24 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Kiener Peter A | Director | A Award deriv | 2022-06-22 | 2022-06-24 | 40,000 | — | $0 | 40,000 | SEC↗ |
| GERAGHTY JAMES A | Director | A Award deriv | 2022-06-22 | 2022-06-24 | 45,000 | — | $0 | 45,000 | SEC↗ |
| Said Maya R. | Director | A Award deriv | 2022-06-22 | 2022-06-24 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Barbier Ann | Director | A Award deriv | 2022-06-22 | 2022-06-24 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Demuth Tim | Chief Medical Officer | P Buy | 2022-05-13 | 2022-05-16 | 6,000 | $1.71 | $10.3K | 6,000 | SEC↗ |
| Yoder Stephen S. | Chief Executive Officer | A Award deriv | 2022-02-22 | 2022-02-24 | 625,874 | — | $0 | 625,874 | SEC↗ |
| Kaufmann Hitto | SVP, Chief Scientific Office | A Award deriv | 2022-02-22 | 2022-02-24 | 215,819 | — | $0 | 215,819 | SEC↗ |
| Bures Thomas | Chief Financial Officer | A Award deriv | 2022-02-22 | 2022-02-24 | 215,819 | — | $0 | 215,819 | SEC↗ |
| Olwill Shane | Chief Development Officer | A Award deriv | 2022-02-22 | 2022-02-24 | 215,819 | — | $0 | 215,819 | SEC↗ |
| Mousa Ahmed | Chief Business Officer | A Award deriv | 2022-02-22 | 2022-02-24 | 215,819 | — | $0 | 215,819 | SEC↗ |
| Demuth Tim | Chief Medical Officer | A Award deriv | 2022-02-22 | 2022-02-24 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Olwill Shane | Chief Development Officer | M Exercise deriv | 2021-08-30 | 2021-09-01 | 38,400 | — | $0 | 61,600 | SEC↗ |
| Olwill Shane | Chief Development Officer | S Sale | 2021-08-30 | 2021-09-01 | 9,200 | $5.00 | $46.0K | 33,838 | SEC↗ |
| Olwill Shane | Chief Development Officer | S Sale | 2021-08-30 | 2021-09-01 | 29,200 | $5.15 | $150.4K | 4,638 | SEC↗ |
| Olwill Shane | Chief Development Officer | M Exercise | 2021-08-30 | 2021-09-01 | 38,400 | $1.52 | $58.4K | 43,038 | SEC↗ |
| Demuth Tim | Chief Medical Officer | A Award deriv | 2021-08-01 | 2021-08-03 | 360,000 | — | $0 | 360,000 | SEC↗ |
| Barbier Ann | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 40,000 | — | $0 | 40,000 | SEC↗ |
| GERAGHTY JAMES A | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 45,000 | — | $0 | 45,000 | SEC↗ |
| Kiener Peter A | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 40,000 | — | $0 | 40,000 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Said Maya R. | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Sherman Matthew L | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Yoder Stephen S. | Chief Executive Officer | A Award deriv | 2021-03-04 | 2021-03-08 | 530,000 | — | $0 | 530,000 | SEC↗ |
| Kaufmann Hitto | SVP, Chief Scientific Office | A Award deriv | 2021-03-04 | 2021-03-08 | 220,000 | — | $0 | 220,000 | SEC↗ |
| Bures Thomas | Vice President, Finance | A Award deriv | 2021-03-04 | 2021-03-08 | 150,000 | — | $0 | 150,000 | SEC↗ |
| Aquilo Capital Management, LLC | 10% Owner | S Sale | 2020-07-21 | 2020-07-22 | 1,900,000 | $2.95 | $5.61M | 3,675,530 | SEC↗ |
| Said Maya R. | Director | A Award deriv | 2020-06-25 | 2020-06-25 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Barbier Ann | Director | A Award deriv | 2020-06-23 | 2020-06-25 | 40,000 | — | $0 | 40,000 | SEC↗ |
| GERAGHTY JAMES A | Director | A Award deriv | 2020-06-23 | 2020-06-25 | 45,000 | — | $0 | 45,000 | SEC↗ |
| Kiener Peter A | Director | A Award deriv | 2020-06-23 | 2020-06-25 | 40,000 | — | $0 | 40,000 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | A Award deriv | 2020-06-23 | 2020-06-25 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2020-06-23 | 2020-06-25 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Sherman Matthew L | Director | A Award deriv | 2020-06-23 | 2020-06-25 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Said Maya R. | Director | A Award deriv | 2020-06-23 | 2020-06-25 | 40,000 | — | $0 | 40,000 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | A Award deriv | 2020-06-23 | 2020-06-25 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Yoder Stephen S. | Chief Executive Officer | A Award deriv | 2020-02-27 | 2020-03-02 | 420,000 | — | $0 | 420,000 | SEC↗ |
| Kaufmann Hitto | SVP, Chief Scientific Office | A Award deriv | 2020-02-27 | 2020-03-02 | 45,000 | — | $0 | 45,000 | SEC↗ |
| Bures Thomas | Vice President, Finance | A Award deriv | 2020-02-27 | 2020-03-02 | 80,000 | — | $0 | 80,000 | SEC↗ |
| GERAGHTY JAMES A | Director | A Award deriv | 2020-01-25 | 2020-01-28 | 22,500 | — | $0 | 22,500 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2020-01-25 | 2020-01-28 | 5,431 | $2.11 | $11.5K | 5,431 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2020-01-25 | 2020-01-28 | 20,000 | — | $0 | 20,000 | SEC↗ |
| BIZZARI JEAN-PIERRE | Director | A Award deriv | 2020-01-25 | 2020-01-28 | 20,000 | — | $0 | 20,000 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | A Award deriv | 2020-01-25 | 2020-01-28 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Barbier Ann | Director | A Award deriv | 2020-01-25 | 2020-01-28 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Kiener Peter A | Director | A Award deriv | 2020-01-25 | 2020-01-28 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Said Maya R. | Director | A Award deriv | 2020-01-25 | 2020-01-28 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Sherman Matthew L | Director | A Award deriv | 2020-01-25 | 2020-01-28 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2019-10-25 | 2019-10-28 | 5,165 | $2.12 | $10.9K | 5,165 | SEC↗ |
| BVF Partners OS Ltd. | Other | S Sale | 2019-09-06 | 2019-09-10 | 25,720 | $4.50 | $115.7K | 2,233,074 | SEC↗ |
| BVF Partners OS Ltd. | Other | S Sale | 2019-09-06 | 2019-09-10 | 1,128 | $4.50 | $5.1K | 314,139 | SEC↗ |
| BVF Partners OS Ltd. | Other | S Sale | 2019-09-06 | 2019-09-10 | 23,152 | $4.50 | $104.2K | 2,385,055 | SEC↗ |
| Kaufmann Hitto | SVP, Chief Scientific Office | A Award deriv | 2019-08-30 | 2019-09-03 | 300,000 | — | $0 | 300,000 | SEC↗ |
| Said Maya R. | Director | A Award deriv | 2019-07-31 | 2019-08-01 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2019-07-25 | 2019-07-26 | 3,789 | $2.89 | $11.0K | 3,789 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2019-04-25 | 2019-04-30 | 5,640 | $1.94 | $10.9K | 5,640 | SEC↗ |
| Yoder Stephen S. | Chief Executive Officer | A Award deriv | 2019-02-26 | 2019-02-28 | 380,000 | — | $0 | 380,000 | SEC↗ |
| Reine Allan | Chief Financial Officer | A Award deriv | 2019-02-26 | 2019-02-28 | 162,500 | — | $0 | 162,500 | SEC↗ |
| Matis Louis | Chief Development Officer | A Award deriv | 2019-02-26 | 2019-02-28 | 96,500 | — | $0 | 96,500 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND L P | Other | J Other deriv | 2019-01-30 | 2019-02-01 | 284 | — | $0 | 284 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND L P | Other | J Other deriv | 2019-01-30 | 2019-02-01 | 2,143 | — | $0 | 2,143 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND L P | Other | J Other deriv | 2019-01-30 | 2019-02-01 | 2,573 | — | $0 | 2,573 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND L P | Other | J Other | 2019-01-30 | 2019-02-01 | 2,143,000 | — | $0 | 772,324 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND L P | Other | J Other | 2019-01-30 | 2019-02-01 | 2,573,000 | — | $0 | 978,200 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND L P | Other | J Other | 2019-01-30 | 2019-02-01 | 284,000 | — | $0 | 141,346 | SEC↗ |
| GERAGHTY JAMES A | Director | A Award deriv | 2019-01-25 | 2019-01-29 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Barbier Ann | Director | A Award deriv | 2019-01-25 | 2019-01-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| BIZZARI JEAN-PIERRE | Director | A Award deriv | 2019-01-25 | 2019-01-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Kiener Peter A | Director | A Award deriv | 2019-01-25 | 2019-01-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | A Award deriv | 2019-01-25 | 2019-01-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Prelack Steven | Director | A Award deriv | 2019-01-25 | 2019-01-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2019-01-25 | 2019-01-29 | 6,096 | $1.79 | $10.9K | 6,096 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2019-01-25 | 2019-01-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Sherman Matthew L | Director | A Award deriv | 2019-01-25 | 2019-01-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2018-10-25 | 2018-10-29 | 3,829 | $2.86 | $11.0K | 3,829 | SEC↗ |
| Kiener Peter A | Director | A Award deriv | 2018-10-24 | 2018-10-25 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Sherman Matthew L | Director | A Award deriv | 2018-10-24 | 2018-10-25 | 30,000 | — | $0 | 30,000 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | P Buy | 2018-09-14 | 2018-09-17 | 5,000 | $5.11 | $25.6K | 10,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2018-07-25 | 2018-07-26 | 2,837 | $3.86 | $11.0K | 2,837 | SEC↗ |
| GERAGHTY JAMES A | Director | P Buy | 2018-05-15 | 2018-05-16 | 10,000 | $5.75 | $57.5K | 20,000 | SEC↗ |
| ORBIMED ADVISORS LLC | 10% Owner | S Sale | 2018-04-30 | 2018-05-02 | 989,600 | $6.35 | $6.28M | 4,511,130 | SEC↗ |
| ORBIMED ADVISORS LLC | 10% Owner | S Sale | 2018-04-30 | 2018-05-02 | 10,400 | $6.35 | $66.0K | 38,870 | SEC↗ |
| Barbier Ann | Director | A Award deriv | 2018-04-25 | 2018-04-26 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2018-04-25 | 2018-04-26 | 2,665 | $4.10 | $10.9K | 2,665 | SEC↗ |
| Yoder Stephen S. | Chief Executive Officer | A Award deriv | 2018-02-20 | 2018-02-26 | 325,000 | — | $0 | 325,000 | SEC↗ |
| Reine Allan | Chief Financial Officer | A Award deriv | 2018-02-20 | 2018-02-26 | 50,000 | — | $0 | 50,000 | SEC↗ |
| Reine Allan | Chief Financial Officer | A Award deriv | 2018-02-20 | 2018-02-26 | 53,833 | — | $0 | 53,833 | SEC↗ |
| Matis Louis | Chief Development Officer | A Award deriv | 2018-02-20 | 2018-02-26 | 100,000 | — | $0 | 100,000 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2018-02-13 | 2018-02-15 | 6,057 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2018-02-13 | 2018-02-15 | 58 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2018-02-13 | 2018-02-15 | 1,765 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2018-02-13 | 2018-02-15 | 17 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | S Sale | 2018-02-13 | 2018-02-15 | 75 | $8.98 | $674 | 49,270 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2018-02-13 | 2018-02-15 | 58 | $4.68 | $271 | 49,328 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2018-02-13 | 2018-02-15 | 1,765 | $5.08 | $9.0K | 5,508,552 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2018-02-13 | 2018-02-15 | 17 | $5.08 | $86 | 49,345 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | S Sale | 2018-02-13 | 2018-02-15 | 7,822 | $8.98 | $70.2K | 5,500,730 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2018-02-13 | 2018-02-15 | 6,057 | $4.68 | $28.3K | 5,506,787 | SEC↗ |
| GERAGHTY JAMES A | Director | A Award deriv | 2018-01-25 | 2018-01-29 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Prelack Steven | Director | A Award deriv | 2018-01-25 | 2018-01-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2018-01-25 | 2018-01-29 | 2,243 | $5.09 | $11.4K | 2,243 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2018-01-25 | 2018-01-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| BIZZARI JEAN-PIERRE | Director | A Award deriv | 2018-01-25 | 2018-01-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| ADAMS JULIAN | Director | A Award deriv | 2018-01-25 | 2018-01-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | A Award deriv | 2018-01-25 | 2018-01-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| ISALY SAMUEL D | 10% Owner | S Sale | 2018-01-03 | 2018-01-04 | 1,693,492 | $7.35 | $12.45M | 5,500,730 | SEC↗ |
| ISALY SAMUEL D | 10% Owner | S Sale | 2018-01-03 | 2018-01-04 | 16,128 | $7.35 | $118.5K | 49,270 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 259 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 27,241 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 97 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 10,180 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 83 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 19,811 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 189 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 8,097 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 77 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 9,642 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 92 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 10,182 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 97 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 5,227 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 50 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 6,654 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 63 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 8,717 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 47 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 4,971 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 99 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 10,447 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 97 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 10,216 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 142 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise deriv | 2017-12-18 | 2017-12-20 | 14,858 | — | $0 | 0 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 10,180 | $1.62 | $16.5K | 7,252,241 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 83 | $1.94 | $161 | 65,853 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 8,717 | $1.94 | $16.9K | 7,242,061 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | S Sale | 2017-12-18 | 2017-12-20 | 1,392 | $5.70 | $7.9K | 65,398 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 63 | $2.62 | $165 | 65,770 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 6,654 | $2.62 | $17.4K | 7,233,344 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 50 | $3.00 | $150 | 65,707 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 5,227 | $3.00 | $15.7K | 7,226,690 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 259 | $2.00 | $518 | 65,657 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 27,241 | $2.00 | $54.5K | 7,221,463 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | S Sale | 2017-12-18 | 2017-12-20 | 146,243 | $5.70 | $833.6K | 7,194,222 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 47 | $5.64 | $265 | 66,790 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 4,971 | $5.64 | $28.0K | 7,340,465 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 99 | $2.32 | $230 | 66,743 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 10,447 | $2.32 | $24.2K | 7,335,494 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 97 | $2.01 | $195 | 66,644 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 10,216 | $2.01 | $20.5K | 7,325,047 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 142 | $2.01 | $285 | 66,547 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 14,858 | $2.01 | $29.9K | 7,314,831 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 97 | $1.64 | $159 | 66,405 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 10,182 | $1.64 | $16.7K | 7,299,973 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 92 | $1.73 | $159 | 66,308 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 9,642 | $1.73 | $16.7K | 7,289,791 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 77 | $2.05 | $158 | 66,216 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 8,097 | $2.05 | $16.6K | 7,280,149 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 189 | $1.59 | $301 | 66,139 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 19,811 | $1.59 | $31.5K | 7,272,052 | SEC↗ |
| OrbiMed Capital GP III LLC | 10% Owner | M Exercise | 2017-12-18 | 2017-12-20 | 97 | $1.62 | $157 | 65,950 | SEC↗ |
| GERAGHTY JAMES A | Director | A Award deriv | 2017-12-12 | 2017-12-14 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | A Award deriv | 2017-10-25 | 2017-10-27 | 6,115 | — | $0 | 6,115 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2017-10-25 | 2017-10-27 | 4,006 | — | $0 | 4,006 | SEC↗ |
| Reine Allan | See Remarks | P Buy | 2017-08-17 | 2017-08-17 | 20,000 | $4.89 | $97.8K | 65,000 | SEC↗ |
| GERAGHTY JAMES A | Director | P Buy | 2017-08-17 | 2017-08-17 | 10,000 | $4.82 | $48.2K | 10,000 | SEC↗ |
| Reine Allan | See Remarks | P Buy | 2017-08-16 | 2017-08-17 | 45,000 | $4.79 | $215.6K | 45,000 | SEC↗ |
| Reine Allan | See Remarks | A Award deriv | 2017-08-09 | 2017-08-11 | 450,000 | — | $0 | 450,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2017-07-25 | 2017-07-27 | 3,288 | — | $0 | 3,288 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | A Award deriv | 2017-07-25 | 2017-07-27 | 5,018 | — | $0 | 5,018 | SEC↗ |
| GERAGHTY JAMES A | Director | A Award deriv | 2017-05-22 | 2017-05-24 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2017-04-25 | 2017-04-27 | 7,821 | — | $0 | 7,821 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | A Award deriv | 2017-04-25 | 2017-04-27 | 10,546 | — | $0 | 10,546 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | M Exercise deriv | 2017-04-21 | 2017-05-09 | 5,000 | — | $0 | 25,000 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | M Exercise | 2017-04-21 | 2017-05-09 | 5,000 | $1.59 | $8.0K | 5,000 | SEC↗ |
| Matis Louis | See Remarks | A Award deriv | 2017-02-23 | 2017-03-06 | 145,000 | — | $0 | 145,000 | SEC↗ |
| Yoder Stephen S. | Chief Executive Officer | A Award deriv | 2017-02-23 | 2017-03-06 | 434,350 | — | $0 | 434,350 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | A Award deriv | 2017-01-25 | 2017-01-30 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | A Award deriv | 2017-01-25 | 2017-01-30 | 10,313 | — | $0 | 10,313 | SEC↗ |
| Prelack Steven | Director | A Award deriv | 2017-01-25 | 2017-01-30 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2017-01-25 | 2017-01-30 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2017-01-25 | 2017-01-30 | 9,687 | — | $0 | 9,687 | SEC↗ |
| ADAMS JULIAN | Director | A Award deriv | 2017-01-25 | 2017-01-30 | 20,000 | — | $0 | 20,000 | SEC↗ |
| BIZZARI JEAN-PIERRE | Director | A Award deriv | 2017-01-25 | 2017-01-30 | 20,000 | — | $0 | 20,000 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | A Award deriv | 2017-01-25 | 2017-01-30 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Knopf Claude | Chief Business Officer | A Award deriv | 2016-11-28 | 2016-11-30 | 500,000 | — | $0 | 500,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2016-10-25 | 2016-10-27 | 9,656 | — | $0 | 9,656 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | A Award deriv | 2016-10-25 | 2016-10-27 | 10,279 | — | $0 | 10,279 | SEC↗ |
| KIRITSY CHRISTOPHER P | Director | A Award deriv | 2016-09-20 | 2016-09-22 | 30,000 | — | $0 | 30,000 | SEC↗ |
| ADAMS JULIAN | Director | A Award deriv | 2016-07-25 | 2016-07-26 | 30,000 | — | $0 | 30,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2016-07-25 | 2016-08-01 | 9,144 | — | $0 | 9,144 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | A Award deriv | 2016-07-25 | 2016-08-01 | 9,734 | — | $0 | 9,734 | SEC↗ |
| Matis Louis | SVP, Chief Development Offic | P Buy | 2016-06-14 | 2016-06-15 | 7,915 | $1.71 | $13.5K | 10,000 | SEC↗ |
| Matis Louis | SVP, Chief Development Offic | P Buy | 2016-06-13 | 2016-06-15 | 2,085 | $1.68 | $3.5K | 2,085 | SEC↗ |
| Yoder Stephen S. | President and CEO | P Buy | 2016-06-13 | 2016-06-15 | 6,000 | $1.68 | $10.1K | 6,000 | SEC↗ |
| DEPTULA-HICKS DARLENE M | SVP, Chief Financial Officer | P Buy | 2016-06-13 | 2016-06-15 | 5,000 | $1.66 | $8.3K | 5,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2016-04-27 | 2016-04-29 | 7,679 | — | $0 | 7,679 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | A Award deriv | 2016-04-27 | 2016-04-29 | 8,174 | — | $0 | 8,174 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2016-02-16 | 2016-02-18 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | A Award deriv | 2016-02-16 | 2016-02-18 | 20,000 | — | $0 | 20,000 | SEC↗ |
| BIZZARI JEAN-PIERRE | Director | A Award deriv | 2016-02-16 | 2016-02-18 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Prelack Steven | Director | A Award deriv | 2016-02-16 | 2016-02-18 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Yoder Stephen S. | President and CEO | A Award deriv | 2016-02-12 | 2016-02-17 | 492,000 | — | $0 | 492,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2016-01-15 | 2016-01-20 | 9,654 | — | $0 | 9,654 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | A Award deriv | 2016-01-15 | 2016-01-20 | 10,277 | — | $0 | 10,277 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2015-10-15 | 2015-10-30 | 8,267 | — | $0 | 8,267 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | A Award deriv | 2015-10-15 | 2015-10-30 | 8,800 | — | $0 | 8,800 | SEC↗ |
| DEPTULA-HICKS DARLENE M | Sr. Vice President and CFO | A Award deriv | 2015-09-01 | 2015-09-03 | 450,000 | — | $0 | 450,000 | SEC↗ |
| Matis Louis | SVP, Chief Development Offic | A Award deriv | 2015-08-17 | 2015-08-18 | 500,000 | — | $0 | 500,000 | SEC↗ |
| Richman Michael | Director | A Award deriv | 2015-07-15 | 2015-07-17 | 6,310 | — | $0 | 6,310 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | A Award deriv | 2015-07-15 | 2015-07-17 | 6,717 | — | $0 | 6,717 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | P Buy | 2015-07-06 | 2015-07-08 | 495,283 | $2.75 | $1.36M | 7,194,222 | SEC↗ |
| Khuong Chau Quang | Director, 10% Owner | P Buy | 2015-07-06 | 2015-07-08 | 4,717 | $2.75 | $13.0K | 65,398 | SEC↗ |
| ISALY SAMUEL D | Director, 10% Owner | P Buy | 2015-07-06 | 2015-07-08 | 495,283 | $2.75 | $1.36M | 7,194,222 | SEC↗ |
| ISALY SAMUEL D | Director, 10% Owner | P Buy | 2015-07-06 | 2015-07-08 | 4,717 | $2.75 | $13.0K | 65,398 | SEC↗ |