PLRX

PLIANT THERAPEUTICS, INC.CIK 1746473 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for PLRX PRO

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AI insights for PLRX

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Raben David	Chief Medical Officer	1	$0	$0	2026-10-01
Borellini Flavia	Director	1	$0	$0	2026-07-09
Iannone Robert	Director	1	$0	$0	2026-07-09
Krognes Steve E.	Director	3	$0	$0	2026-06-11
Cline Darren S	Director	5	$0	$0	2026-06-11
Curnutte John T	Director	6	$0	$0	2026-06-11
MCCOURT Thomas A	Director	5	$0	$0	2026-06-11
Huh Hoyoung	Director	8	$0	$0	2026-06-11
CROWELL GAYLE A	Director	6	$0	$0	2026-06-11
Kuo Minnie	Chief Operating Officer	8	$0	$8.9K	2026-04-17
Cheung Lily	Chief Human Resource Officer	14	$0	$51.5K	2026-04-17
Cummings Keith Lamont	Chief Financial Officer	67	$0	$2.97M	2026-04-17
Coulie Bernard	President and CEO	123	$0	$13.58M	2026-04-17
Knobil Katharine	Director	4	$0	$0	2025-06-05
Bruhn Suzanne Louise	Director	5	$0	$0	2025-06-05
PYOTT DAVID E I	Director	7	$0	$0	2025-06-05
Ouimette Mike	General Counsel & Corp. Sec'y	29	$0	$1.79M	2025-01-23
Hull Hans	Chief Business Officer	35	$0	$1.89M	2025-01-23
Lefebvre Eric	Chief Medical Officer	28	$0	$5.13M	2025-01-23
Shah Smital	Director	4	$0	$0	2024-06-13
Third Rock Ventures III, L.P.	10% Owner	2	$0	$0	2022-11-29
Exter Neil	Director	5	$0	$0	2022-06-16
HOMCY CHARLES J	Director	1	$0	$0	2021-06-29
Howes Barbara	Chief Human Resource Officer	5	$0	$0	2021-01-23
TRV GP IV, LLC	10% Owner	4	$0	$0	2020-06-05
Green Jeremy	10% Owner	2	$0	$0	2020-06-05

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Raben David	Chief Medical Officer	A Award deriv	2026-10-01	2026-10-02	575,000	—	$0	575,000	SEC↗
Borellini Flavia	Director	A Award deriv	2026-07-09	2026-07-13	60,000	—	$0	60,000	SEC↗
Iannone Robert	Director	A Award deriv	2026-07-09	2026-07-13	60,000	—	$0	60,000	SEC↗
Cline Darren S	Director	A Award deriv	2026-06-11	2026-06-12	70,000	—	$0	70,000	SEC↗
Huh Hoyoung	Director	A Award deriv	2026-06-11	2026-06-12	70,000	—	$0	70,000	SEC↗
Curnutte John T	Director	A Award deriv	2026-06-11	2026-06-12	70,000	—	$0	70,000	SEC↗
Krognes Steve E.	Director	A Award deriv	2026-06-11	2026-06-12	70,000	—	$0	70,000	SEC↗
MCCOURT Thomas A	Director	A Award deriv	2026-06-11	2026-06-12	70,000	—	$0	70,000	SEC↗
CROWELL GAYLE A	Director	A Award deriv	2026-06-11	2026-06-12	70,000	—	$0	70,000	SEC↗
Cheung Lily	Chief Human Resource Officer	D To issuer deriv	2026-04-17	2026-04-17	51,750	—	$0	0	SEC↗
Cheung Lily	Chief Human Resource Officer	A Award deriv	2026-04-17	2026-04-17	51,750	—	$0	51,750	SEC↗
Cheung Lily	Chief Human Resource Officer	D To issuer deriv	2026-04-17	2026-04-17	123,000	—	$0	0	SEC↗
Cheung Lily	Chief Human Resource Officer	A Award deriv	2026-04-17	2026-04-17	123,000	—	$0	123,000	SEC↗
Cheung Lily	Chief Human Resource Officer	D To issuer deriv	2026-04-17	2026-04-17	52,000	—	$0	0	SEC↗
Cheung Lily	Chief Human Resource Officer	A Award deriv	2026-04-17	2026-04-17	52,000	—	$0	52,000	SEC↗
Coulie Bernard	President and CEO	D To issuer deriv	2026-04-17	2026-04-17	146,841	—	$0	0	SEC↗
Coulie Bernard	President and CEO	A Award deriv	2026-04-17	2026-04-17	146,841	—	$0	146,841	SEC↗
Coulie Bernard	President and CEO	D To issuer deriv	2026-04-17	2026-04-17	327,262	—	$0	0	SEC↗
Coulie Bernard	President and CEO	A Award deriv	2026-04-17	2026-04-17	327,262	—	$0	327,262	SEC↗
Coulie Bernard	President and CEO	A Award deriv	2026-04-17	2026-04-17	325,000	—	$0	325,000	SEC↗
Coulie Bernard	President and CEO	A Award deriv	2026-04-17	2026-04-17	250,000	—	$0	250,000	SEC↗
Coulie Bernard	President and CEO	D To issuer deriv	2026-04-17	2026-04-17	440,000	—	$0	0	SEC↗
Coulie Bernard	President and CEO	A Award deriv	2026-04-17	2026-04-17	440,000	—	$0	440,000	SEC↗
Coulie Bernard	President and CEO	D To issuer deriv	2026-04-17	2026-04-17	206,300	—	$0	0	SEC↗
Coulie Bernard	President and CEO	A Award deriv	2026-04-17	2026-04-17	206,300	—	$0	206,300	SEC↗
Coulie Bernard	President and CEO	D To issuer deriv	2026-04-17	2026-04-17	256,300	—	$0	0	SEC↗
Coulie Bernard	President and CEO	A Award deriv	2026-04-17	2026-04-17	256,300	—	$0	256,300	SEC↗
Coulie Bernard	President and CEO	D To issuer deriv	2026-04-17	2026-04-17	325,000	—	$0	0	SEC↗
Coulie Bernard	President and CEO	D To issuer deriv	2026-04-17	2026-04-17	250,000	—	$0	0	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award deriv	2026-04-17	2026-04-17	18,198	—	$0	18,198	SEC↗
Cummings Keith Lamont	Chief Financial Officer	D To issuer deriv	2026-04-17	2026-04-17	74,250	—	$0	0	SEC↗
Cummings Keith Lamont	Chief Financial Officer	D To issuer deriv	2026-04-17	2026-04-17	76,200	—	$0	0	SEC↗
Cummings Keith Lamont	Chief Financial Officer	D To issuer deriv	2026-04-17	2026-04-17	18,198	—	$0	0	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award deriv	2026-04-17	2026-04-17	76,047	—	$0	76,047	SEC↗
Cummings Keith Lamont	Chief Financial Officer	D To issuer deriv	2026-04-17	2026-04-17	76,047	—	$0	0	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award deriv	2026-04-17	2026-04-17	74,250	—	$0	74,250	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award deriv	2026-04-17	2026-04-17	76,200	—	$0	76,200	SEC↗
Cummings Keith Lamont	Chief Financial Officer	D To issuer deriv	2026-04-17	2026-04-17	110,500	—	$0	0	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award deriv	2026-04-17	2026-04-17	110,500	—	$0	110,500	SEC↗
Cummings Keith Lamont	Chief Financial Officer	D To issuer deriv	2026-04-17	2026-04-17	113,300	—	$0	0	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award deriv	2026-04-17	2026-04-17	113,300	—	$0	113,300	SEC↗
Cummings Keith Lamont	Chief Financial Officer	D To issuer deriv	2026-04-17	2026-04-17	124,000	—	$0	0	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award deriv	2026-04-17	2026-04-17	124,000	—	$0	124,000	SEC↗
Kuo Minnie	Chief Operating Officer	A Award deriv	2026-04-17	2026-04-17	150,000	—	$0	150,000	SEC↗
Kuo Minnie	Chief Operating Officer	D To issuer deriv	2026-04-17	2026-04-17	150,000	—	$0	0	SEC↗
Kuo Minnie	Chief Operating Officer	A Award deriv	2026-04-17	2026-04-17	40,000	—	$0	40,000	SEC↗
Kuo Minnie	Chief Operating Officer	D To issuer deriv	2026-04-17	2026-04-17	55,200	—	$0	0	SEC↗
Kuo Minnie	Chief Operating Officer	A Award deriv	2026-04-17	2026-04-17	55,200	—	$0	55,200	SEC↗
Kuo Minnie	Chief Operating Officer	D To issuer deriv	2026-04-17	2026-04-17	40,000	—	$0	0	SEC↗
Coulie Bernard	President and CEO	A Award deriv	2026-01-22	2026-01-26	1,230,000	—	$0	1,230,000	SEC↗
Cheung Lily	Chief Human Resource Officer	A Award deriv	2026-01-22	2026-01-26	300,000	—	$0	300,000	SEC↗
Kuo Minnie	Chief Operating Officer	A Award deriv	2026-01-22	2026-01-26	300,000	—	$0	300,000	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award deriv	2026-01-22	2026-01-26	400,000	—	$0	400,000	SEC↗
Kuo Minnie	Chief Operating Officer	S Sale	2026-01-20	2026-01-22	6,917	$1.28	$8.9K	37,806	SEC↗
Coulie Bernard	President and CEO	S Sale	2026-01-20	2026-01-22	89,375	$1.28	$114.4K	505,601	SEC↗
Cheung Lily	Chief Human Resource Officer	S Sale	2026-01-20	2026-01-22	7,534	$1.28	$9.6K	44,847	SEC↗
Cummings Keith Lamont	Chief Financial Officer	S Sale	2026-01-20	2026-01-22	24,002	$1.28	$30.7K	297,214	SEC↗
CROWELL GAYLE A	Director	A Award deriv	2025-06-05	2025-06-09	30,000	—	$0	30,000	SEC↗
Huh Hoyoung	Director	A Award deriv	2025-06-05	2025-06-09	30,000	—	$0	30,000	SEC↗
PYOTT DAVID E I	Director	A Award deriv	2025-06-05	2025-06-09	30,000	—	$0	30,000	SEC↗
Cline Darren S	Director	A Award deriv	2025-06-05	2025-06-09	30,000	—	$0	30,000	SEC↗
Krognes Steve E.	Director	A Award deriv	2025-06-05	2025-06-09	30,000	—	$0	30,000	SEC↗
Curnutte John T	Director	A Award deriv	2025-06-05	2025-06-09	30,000	—	$0	30,000	SEC↗
MCCOURT Thomas A	Director	A Award deriv	2025-06-05	2025-06-09	30,000	—	$0	30,000	SEC↗
Knobil Katharine	Director	A Award deriv	2025-06-05	2025-06-09	30,000	—	$0	30,000	SEC↗
Bruhn Suzanne Louise	Director	A Award deriv	2025-06-05	2025-06-09	30,000	—	$0	30,000	SEC↗
Coulie Bernard	President and CEO	A Award deriv	2025-01-23	2025-01-27	325,000	—	$0	325,000	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award deriv	2025-01-23	2025-01-27	113,300	—	$0	113,300	SEC↗
Lefebvre Eric	Chief Medical Officer	A Award deriv	2025-01-23	2025-01-27	91,300	—	$0	91,300	SEC↗
Hull Hans	Chief Business Officer	A Award deriv	2025-01-23	2025-01-27	80,300	—	$0	80,300	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	A Award deriv	2025-01-23	2025-01-27	70,000	—	$0	70,000	SEC↗
Cheung Lily	Chief Human Resource Officer	A Award deriv	2025-01-23	2025-01-27	51,750	—	$0	51,750	SEC↗
Coulie Bernard	President and CEO	A Award	2025-01-23	2025-01-27	162,500	—	$0	593,017	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award	2025-01-23	2025-01-27	56,650	—	$0	319,258	SEC↗
Lefebvre Eric	Chief Medical Officer	A Award	2025-01-23	2025-01-27	45,650	—	$0	240,224	SEC↗
Hull Hans	Chief Business Officer	A Award	2025-01-23	2025-01-27	40,150	—	$0	251,708	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	A Award	2025-01-23	2025-01-27	35,000	—	$0	105,544	SEC↗
Cheung Lily	Chief Human Resource Officer	A Award	2025-01-23	2025-01-27	25,875	—	$0	50,425	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	S Sale	2025-01-22	2025-01-22	10,230	$10.99	$112.4K	70,544	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	S Sale	2025-01-17	2025-01-22	13,270	$11.20	$148.6K	80,774	SEC↗
Cheung Lily	Chief Human Resource Officer	S Sale	2025-01-17	2025-01-22	3,740	$11.20	$41.9K	24,550	SEC↗
Lefebvre Eric	Chief Medical Officer	S Sale	2025-01-17	2025-01-22	18,478	$11.20	$207.0K	194,574	SEC↗
Hull Hans	Chief Business Officer	S Sale	2025-01-17	2025-01-22	15,936	$11.20	$178.5K	211,558	SEC↗
Cummings Keith Lamont	Chief Financial Officer	S Sale	2025-01-17	2025-01-22	20,148	$11.20	$225.7K	262,608	SEC↗
Coulie Bernard	President and CEO	S Sale	2025-01-17	2025-01-22	52,419	$11.20	$587.1K	430,517	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	S Sale	2024-07-10	2024-07-12	7,656	$11.56	$88.5K	94,044	SEC↗
Coulie Bernard	President and CEO	S Sale	2024-07-10	2024-07-12	38,710	$11.56	$447.5K	482,936	SEC↗
Cummings Keith Lamont	Chief Financial Officer	S Sale	2024-07-10	2024-07-12	10,911	$11.56	$126.1K	282,115	SEC↗
Hull Hans	Chief Business Officer	S Sale	2024-07-10	2024-07-12	9,900	$11.56	$114.4K	227,494	SEC↗
Lefebvre Eric	Chief Medical Officer	S Sale	2024-07-10	2024-07-12	12,319	$11.56	$142.4K	213,052	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	A Award	2024-07-09	2024-07-11	14,954	—	$0	101,700	SEC↗
Coulie Bernard	President and CEO	A Award	2024-07-09	2024-07-11	75,625	—	$0	521,646	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award	2024-07-09	2024-07-11	21,313	—	$0	293,026	SEC↗
Hull Hans	Chief Business Officer	A Award	2024-07-09	2024-07-11	19,337	—	$0	237,394	SEC↗
Lefebvre Eric	Chief Medical Officer	A Award	2024-07-09	2024-07-11	24,063	—	$0	225,371	SEC↗
Krognes Steve E.	Director	A Award deriv	2024-06-13	2024-06-17	53,528	—	$0	53,528	SEC↗
Curnutte John T	Director	A Award deriv	2024-06-13	2024-06-17	26,764	—	$0	26,764	SEC↗
Bruhn Suzanne Louise	Director	A Award deriv	2024-06-13	2024-06-17	26,764	—	$0	26,764	SEC↗
CROWELL GAYLE A	Director	A Award deriv	2024-06-13	2024-06-17	26,764	—	$0	26,764	SEC↗
Cline Darren S	Director	A Award deriv	2024-06-13	2024-06-17	26,764	—	$0	26,764	SEC↗
Shah Smital	Director	A Award deriv	2024-06-13	2024-06-17	26,764	—	$0	26,764	SEC↗
PYOTT DAVID E I	Director	A Award deriv	2024-06-13	2024-06-17	26,764	—	$0	26,764	SEC↗
Huh Hoyoung	Director	A Award deriv	2024-06-13	2024-06-17	26,764	—	$0	26,764	SEC↗
Knobil Katharine	Director	A Award deriv	2024-06-13	2024-06-17	26,764	—	$0	26,764	SEC↗
MCCOURT Thomas A	Director	A Award deriv	2024-06-13	2024-06-17	26,764	—	$0	26,764	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise deriv	2024-05-02	2024-05-06	21,000	—	$0	76,047	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise	2024-05-02	2024-05-06	21,000	$2.08	$43.7K	271,713	SEC↗
Coulie Bernard	President and CEO	A Award deriv	2024-01-23	2024-01-24	256,300	—	$0	256,300	SEC↗
Cheung Lily	Chief Human Resource Officer	A Award deriv	2024-01-23	2024-01-24	52,000	—	$0	52,000	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award deriv	2024-01-23	2024-01-24	110,500	—	$0	110,500	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	A Award deriv	2024-01-23	2024-01-24	63,000	—	$0	63,000	SEC↗
Hull Hans	Chief Business Officer	A Award deriv	2024-01-23	2024-01-24	63,000	—	$0	63,000	SEC↗
Lefebvre Eric	Chief Medical Officer	A Award deriv	2024-01-23	2024-01-24	85,800	—	$0	85,800	SEC↗
Coulie Bernard	President and CEO	A Award	2024-01-23	2024-01-24	128,150	—	$0	444,532	SEC↗
Cheung Lily	Chief Human Resource Officer	A Award	2024-01-23	2024-01-24	26,000	—	$0	26,795	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award	2024-01-23	2024-01-24	55,250	—	$0	249,855	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	A Award	2024-01-23	2024-01-24	31,500	—	$0	86,746	SEC↗
Hull Hans	Chief Business Officer	A Award	2024-01-23	2024-01-24	31,500	—	$0	216,569	SEC↗
Lefebvre Eric	Chief Medical Officer	A Award	2024-01-23	2024-01-24	42,900	—	$0	199,820	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	S Sale	2024-01-17	2024-01-19	5,197	$17.23	$89.5K	55,246	SEC↗
Lefebvre Eric	Chief Medical Officer	S Sale	2024-01-17	2024-01-19	10,295	$17.23	$177.4K	156,920	SEC↗
Coulie Bernard	President and CEO	S Sale	2024-01-17	2024-01-19	25,721	$17.23	$443.2K	316,382	SEC↗
Hull Hans	Chief Business Officer	S Sale	2024-01-17	2024-01-19	9,786	$17.23	$168.6K	185,069	SEC↗
Cummings Keith Lamont	Chief Financial Officer	S Sale	2024-01-17	2024-01-19	9,781	$17.23	$168.5K	194,605	SEC↗
Hull Hans	Chief Business Officer	M Exercise deriv	2023-08-04	2023-08-07	8,791	—	$0	31,367	SEC↗
Hull Hans	Chief Business Officer	M Exercise	2023-08-04	2023-08-07	8,791	$2.08	$18.3K	214,905	SEC↗
Hull Hans	Chief Business Officer	S Sale	2023-08-04	2023-08-07	20,050	$20.01	$401.2K	194,855	SEC↗
Hull Hans	Chief Business Officer	M Exercise deriv	2023-08-03	2023-08-07	1,800	—	$0	40,158	SEC↗
Hull Hans	Chief Business Officer	S Sale	2023-08-03	2023-08-07	1,800	$20.00	$36.0K	206,114	SEC↗
Hull Hans	Chief Business Officer	S Sale	2023-08-03	2023-08-07	13,069	$20.00	$261.4K	206,114	SEC↗
Hull Hans	Chief Business Officer	M Exercise	2023-08-03	2023-08-07	1,800	$2.08	$3.7K	207,914	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	S Sale	2023-07-20	2023-07-21	4,755	$17.55	$83.5K	60,443	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-07-17	2023-07-19	70,150	$18.01	$1.26M	342,103	SEC↗
Cummings Keith Lamont	Chief Financial Officer	S Sale	2023-07-17	2023-07-19	19,771	$18.01	$356.1K	203,999	SEC↗
Hull Hans	Chief Business Officer	S Sale	2023-07-17	2023-07-19	17,937	$18.01	$323.0K	219,183	SEC↗
Lefebvre Eric	Chief Medical Officer	S Sale	2023-07-17	2023-07-19	22,321	$18.01	$402.0K	167,215	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	S Sale	2023-07-17	2023-07-19	12,778	$18.01	$230.1K	65,198	SEC↗
Coulie Bernard	President and CEO	A Award	2023-07-14	2023-07-18	137,500	—	$0	412,253	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award	2023-07-14	2023-07-18	38,750	—	$0	223,770	SEC↗
Hull Hans	Chief Business Officer	A Award	2023-07-14	2023-07-18	35,156	—	$0	237,120	SEC↗
Lefebvre Eric	Chief Medical Officer	A Award	2023-07-14	2023-07-18	43,750	—	$0	189,536	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	A Award	2023-07-14	2023-07-18	27,187	—	$0	77,976	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise deriv	2023-06-13	2023-06-14	30,750	—	$0	97,047	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise	2023-06-13	2023-06-14	30,750	$2.08	$64.0K	185,020	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise deriv	2023-06-09	2023-06-12	5,800	—	$0	127,797	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise	2023-06-09	2023-06-12	5,800	$2.08	$12.1K	154,270	SEC↗
Bruhn Suzanne Louise	Director	A Award deriv	2023-06-07	2023-06-08	14,000	—	$0	14,000	SEC↗
Cline Darren S	Director	A Award deriv	2023-06-07	2023-06-08	14,000	—	$0	14,000	SEC↗
CROWELL GAYLE A	Director	A Award deriv	2023-06-07	2023-06-08	14,000	—	$0	14,000	SEC↗
Curnutte John T	Director	A Award deriv	2023-06-07	2023-06-08	14,000	—	$0	14,000	SEC↗
Huh Hoyoung	Director	A Award deriv	2023-06-07	2023-06-08	14,000	—	$0	14,000	SEC↗
Knobil Katharine	Director	A Award deriv	2023-06-07	2023-06-08	14,000	—	$0	14,000	SEC↗
MCCOURT Thomas A	Director	A Award deriv	2023-06-07	2023-06-08	14,000	—	$0	14,000	SEC↗
PYOTT DAVID E I	Director	A Award deriv	2023-06-07	2023-06-08	14,000	—	$0	14,000	SEC↗
Shah Smital	Director	A Award deriv	2023-06-07	2023-06-08	14,000	—	$0	14,000	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	S Sale	2023-04-03	2023-04-03	200	$27.46	$5.5K	50,789	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	S Sale	2023-04-03	2023-04-03	2,677	$26.74	$71.6K	50,989	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-03-30	2023-04-03	35,339	$26.52	$937.2K	274,753	SEC↗
Cummings Keith Lamont	Chief Financial Officer	S Sale	2023-03-30	2023-04-03	9,960	$26.52	$264.1K	148,470	SEC↗
Hull Hans	Chief Business Officer	S Sale	2023-03-30	2023-04-03	9,036	$26.52	$239.6K	201,964	SEC↗
Lefebvre Eric	Chief Medical Officer	S Sale	2023-03-30	2023-04-03	11,245	$26.52	$298.2K	145,786	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	S Sale	2023-03-30	2023-04-03	4,874	$26.52	$129.3K	53,666	SEC↗
Coulie Bernard	President and CEO	A Award	2023-03-29	2023-03-31	68,749	—	$0	310,092	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award	2023-03-29	2023-03-31	19,375	—	$0	158,430	SEC↗
Hull Hans	Chief Business Officer	A Award	2023-03-29	2023-03-31	17,578	—	$0	211,000	SEC↗
Lefebvre Eric	Chief Medical Officer	A Award	2023-03-29	2023-03-31	21,874	—	$0	157,031	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	A Award	2023-03-29	2023-03-31	13,593	—	$0	58,540	SEC↗
Cline Darren S	Director	A Award deriv	2023-03-06	2023-03-08	22,000	—	$0	22,000	SEC↗
MCCOURT Thomas A	Director	A Award deriv	2023-03-06	2023-03-08	22,000	—	$0	22,000	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-02-03	2023-02-06	15,000	—	$0	327,262	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-02-03	2023-02-06	9,738	$33.36	$324.9K	245,374	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-02-03	2023-02-06	15,000	$6.22	$93.3K	255,112	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-02-03	2023-02-06	5,262	$34.08	$179.3K	240,112	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-02-02	2023-02-06	15,000	—	$0	342,262	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-02-02	2023-02-06	15,000	$6.22	$93.3K	255,112	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-02-02	2023-02-06	13,395	$34.13	$457.2K	241,717	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-02-02	2023-02-06	1,605	$34.96	$56.1K	240,112	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-02-01	2023-02-01	15,000	—	$0	357,262	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-02-01	2023-02-01	105	$35.55	$3.7K	240,112	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-02-01	2023-02-01	5,440	$34.78	$189.2K	240,217	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-02-01	2023-02-01	9,455	$34.15	$322.9K	245,657	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-02-01	2023-02-01	15,000	$6.22	$93.3K	255,112	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-01-31	2023-02-01	10,539	—	$0	146,841	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-01-31	2023-02-01	4,461	—	$0	372,262	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-01-31	2023-02-01	4,461	$6.22	$27.7K	255,112	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-31	2023-02-01	15,000	$34.92	$523.8K	240,112	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-01-31	2023-02-01	10,539	$2.08	$21.9K	250,651	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-01-30	2023-02-01	15,000	—	$0	157,380	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-01-30	2023-02-01	15,000	$2.08	$31.2K	255,112	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-30	2023-02-01	11,395	$33.98	$387.2K	243,717	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-30	2023-02-01	3,605	$34.66	$124.9K	240,112	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-27	2023-01-27	9,779	$35.09	$343.1K	409,538	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-27	2023-01-27	221	$36.64	$8.1K	409,317	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-27	2023-01-27	6,302	$36.06	$227.3K	240,112	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-27	2023-01-27	8,698	$35.42	$308.1K	246,414	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-01-27	2023-01-27	15,000	$2.08	$31.2K	255,112	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-01-26	2023-01-27	15,000	—	$0	187,380	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-01-26	2023-01-27	15,000	—	$0	172,380	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-26	2023-01-27	15,000	$35.10	$526.5K	419,317	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-01-26	2023-01-27	15,000	$2.08	$31.2K	255,112	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-26	2023-01-27	15,000	$35.29	$529.4K	240,112	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-01-25	2023-01-25	15,000	—	$0	202,380	SEC↗
Coulie Bernard	President and CEO	A Award deriv	2023-01-25	2023-01-27	206,300	—	$0	206,300	SEC↗
Lefebvre Eric	Chief Medical Officer	A Award deriv	2023-01-25	2023-01-27	80,000	—	$0	80,000	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	A Award deriv	2023-01-25	2023-01-27	55,000	—	$0	55,000	SEC↗
Hull Hans	Chief Business Officer	A Award deriv	2023-01-25	2023-01-27	76,200	—	$0	76,200	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award deriv	2023-01-25	2023-01-27	76,200	—	$0	76,200	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-01-25	2023-01-25	15,000	$2.08	$31.2K	108,812	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-25	2023-01-25	1,696	$33.29	$56.5K	93,812	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-25	2023-01-25	13,304	$32.40	$431.0K	95,508	SEC↗
Coulie Bernard	President and CEO	A Award	2023-01-25	2023-01-27	146,300	—	$0	240,112	SEC↗
Lefebvre Eric	Chief Medical Officer	A Award	2023-01-25	2023-01-27	57,000	—	$0	133,926	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	A Award	2023-01-25	2023-01-27	39,000	—	$0	44,947	SEC↗
Hull Hans	Chief Business Officer	A Award	2023-01-25	2023-01-27	54,000	—	$0	192,191	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award	2023-01-25	2023-01-27	54,000	—	$0	138,424	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-01-24	2023-01-25	15,000	—	$0	217,380	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-24	2023-01-25	15,000	$30.89	$463.4K	93,812	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-01-24	2023-01-25	15,000	$2.08	$31.2K	108,812	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise deriv	2023-01-23	2023-01-25	17,500	—	$0	18,198	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise deriv	2023-01-23	2023-01-25	12,500	—	$0	133,597	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	M Exercise deriv	2023-01-23	2023-01-25	10,000	—	$0	98,240	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	M Exercise deriv	2023-01-23	2023-01-25	10,000	—	$0	77,000	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-01-23	2023-01-25	15,000	—	$0	232,380	SEC↗
Cummings Keith Lamont	Chief Financial Officer	S Sale	2023-01-23	2023-01-25	30,000	$35.00	$1.05M	84,424	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise	2023-01-23	2023-01-25	12,500	$2.08	$26.0K	96,924	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise	2023-01-23	2023-01-25	17,500	$6.22	$108.8K	114,424	SEC↗
Lefebvre Eric	Chief Medical Officer	S Sale	2023-01-23	2023-01-25	67,500	$34.48	$2.33M	76,926	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	S Sale	2023-01-23	2023-01-25	20,000	$34.19	$683.8K	5,947	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	M Exercise	2023-01-23	2023-01-25	10,000	$24.32	$243.2K	25,947	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	M Exercise	2023-01-23	2023-01-25	10,000	$11.86	$118.6K	15,947	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-23	2023-01-25	10,150	$33.71	$342.2K	98,662	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-01-23	2023-01-25	15,000	$2.08	$31.2K	108,812	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-23	2023-01-25	4,850	$34.93	$169.4K	93,812	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-23	2023-01-25	15,000	$35.00	$525.0K	434,317	SEC↗
Cheung Lily	Chief Human Resource Officer	A Award deriv	2023-01-19	2023-01-23	123,000	—	$0	123,000	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-01-09	2023-01-09	5,000	—	$0	247,380	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-09	2023-01-09	5,000	$19.17	$95.9K	93,812	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-01-09	2023-01-09	5,000	$2.08	$10.4K	98,812	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-01-06	2023-01-09	15,000	—	$0	252,380	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-01-06	2023-01-09	15,000	$2.08	$31.2K	108,812	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-06	2023-01-09	15,000	$19.04	$285.6K	93,812	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-01-04	2023-01-05	15,000	—	$0	267,380	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-01-04	2023-01-05	15,000	$2.08	$31.2K	108,812	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-04	2023-01-05	15,000	$19.06	$285.9K	93,812	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2023-01-03	2023-01-05	15,000	—	$0	282,380	SEC↗
Coulie Bernard	President and CEO	S Sale	2023-01-03	2023-01-05	15,000	$19.33	$289.9K	93,812	SEC↗
Coulie Bernard	President and CEO	M Exercise	2023-01-03	2023-01-05	15,000	$2.08	$31.2K	108,812	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise deriv	2022-12-22	2022-12-27	4,000	—	$0	146,097	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	S Sale	2022-12-22	2022-12-23	2,928	$19.38	$56.7K	5,947	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise	2022-12-22	2022-12-27	4,000	$2.08	$8.3K	84,424	SEC↗
Hull Hans	Chief Business Officer	S Sale	2022-12-20	2022-12-21	8,748	$19.10	$167.1K	138,191	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	S Sale	2022-12-20	2022-12-21	4,719	$19.10	$90.1K	8,875	SEC↗
Lefebvre Eric	Chief Medical Officer	S Sale	2022-12-20	2022-12-21	10,887	$19.10	$207.9K	144,426	SEC↗
Coulie Bernard	President and CEO	S Sale	2022-12-20	2022-12-21	34,212	$19.10	$653.4K	93,812	SEC↗
Cummings Keith Lamont	Chief Financial Officer	S Sale	2022-12-20	2022-12-21	9,643	$19.10	$184.2K	80,424	SEC↗
Hull Hans	Chief Business Officer	A Award	2022-12-19	2022-12-21	17,578	—	$0	146,939	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	A Award	2022-12-19	2022-12-21	13,594	—	$0	13,594	SEC↗
Lefebvre Eric	Chief Medical Officer	A Award	2022-12-19	2022-12-21	21,876	—	$0	155,313	SEC↗
Coulie Bernard	President and CEO	A Award	2022-12-19	2022-12-21	68,751	—	$0	128,024	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award	2022-12-19	2022-12-21	19,375	—	$0	90,067	SEC↗
Third Rock Ventures III, L.P.	10% Owner	J Other	2022-11-29	2022-12-01	2,000,000	—	$0	1,839,160	SEC↗
Lefebvre Eric	Chief Medical Officer	S Sale	2022-10-25	2022-10-27	5,000	$25.05	$125.3K	133,437	SEC↗
Third Rock Ventures III, L.P.	10% Owner	J Other	2022-09-20	2022-09-22	2,000,000	—	$0	3,839,160	SEC↗
Knobil Katharine	Director	A Award deriv	2022-09-14	2022-09-16	30,000	—	$0	30,000	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2022-09-12	2022-09-14	12,502	—	$0	297,380	SEC↗
Coulie Bernard	President and CEO	M Exercise	2022-09-12	2022-09-14	12,502	$2.08	$26.0K	71,775	SEC↗
Coulie Bernard	President and CEO	S Sale	2022-09-12	2022-09-14	12,502	$22.54	$281.8K	59,273	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2022-07-12	2022-07-13	12,498	—	$0	309,882	SEC↗
Coulie Bernard	President and CEO	M Exercise	2022-07-12	2022-07-13	12,498	$2.08	$26.0K	71,771	SEC↗
Coulie Bernard	President and CEO	S Sale	2022-07-12	2022-07-13	12,498	$22.50	$281.2K	59,273	SEC↗
Coulie Bernard	President and CEO	M Exercise deriv	2022-07-11	2022-07-13	15,000	—	$0	322,380	SEC↗
Coulie Bernard	President and CEO	S Sale	2022-07-11	2022-07-13	15,000	$22.50	$337.5K	59,273	SEC↗
Coulie Bernard	President and CEO	M Exercise	2022-07-11	2022-07-13	15,000	$2.08	$31.2K	74,273	SEC↗
Lefebvre Eric	Chief Medical Officer	S Sale	2022-07-11	2022-07-13	3,000	$20.00	$60.0K	138,436	SEC↗
Shah Smital	Director	A Award deriv	2022-06-16	2022-06-21	15,000	—	$0	15,000	SEC↗
Bruhn Suzanne Louise	Director	A Award deriv	2022-06-16	2022-06-21	15,000	—	$0	15,000	SEC↗
CROWELL GAYLE A	Director	A Award deriv	2022-06-16	2022-06-21	15,000	—	$0	15,000	SEC↗
Curnutte John T	Director	A Award deriv	2022-06-16	2022-06-21	15,000	—	$0	15,000	SEC↗
Exter Neil	Director	A Award deriv	2022-06-16	2022-06-21	15,000	—	$0	15,000	SEC↗
Huh Hoyoung	Director	A Award deriv	2022-06-16	2022-06-21	15,000	—	$0	15,000	SEC↗
PYOTT DAVID E I	Director	A Award deriv	2022-06-16	2022-06-21	15,000	—	$0	15,000	SEC↗
Coulie Bernard	President and CEO	A Award deriv	2022-01-26	2022-02-02	440,000	—	$0	440,000	SEC↗
Lefebvre Eric	Chief Medical Officer	A Award deriv	2022-01-26	2022-02-02	140,000	—	$0	140,000	SEC↗
Hull Hans	Chief Business Officer	A Award deriv	2022-01-26	2022-02-02	112,500	—	$0	112,500	SEC↗
Cummings Keith Lamont	Chief Financial Officer	A Award deriv	2022-01-26	2022-02-02	124,000	—	$0	124,000	SEC↗
Ouimette Mike	General Counsel & Corp. Sec'	A Award deriv	2022-01-26	2022-02-02	87,000	—	$0	87,000	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise deriv	2021-09-03	2021-09-03	20,000	—	$0	150,097	SEC↗
Cummings Keith Lamont	Chief Financial Officer	M Exercise	2021-09-03	2021-09-03	20,000	$2.08	$41.6K	67,621	SEC↗
PYOTT DAVID E I	Director	A Award deriv	2021-06-29	2021-07-01	13,286	—	$0	13,286	SEC↗
Bruhn Suzanne Louise	Director	A Award deriv	2021-06-29	2021-06-30	13,286	—	$0	13,286	SEC↗
CROWELL GAYLE A	Director	A Award deriv	2021-06-29	2021-06-30	13,286	—	$0	13,286	SEC↗
Curnutte John T	Director	A Award deriv	2021-06-29	2021-06-30	13,286	—	$0	13,286	SEC↗
Exter Neil	Director	A Award deriv	2021-06-29	2021-06-30	13,286	—	$0	13,286	SEC↗
HOMCY CHARLES J	Director	A Award deriv	2021-06-29	2021-06-30	13,286	—	$0	13,286	SEC↗
Huh Hoyoung	Director	A Award deriv	2021-06-29	2021-06-30	13,286	—	$0	13,286	SEC↗
PYOTT DAVID E I	Director	A Award deriv	2021-06-29	2021-06-30	13,286	—	$0	13,286	SEC↗
Shah Smital	Director	A Award deriv	2021-06-29	2021-06-30	13,286	—	$0	13,286	SEC↗
Lefebvre Eric	Chief Medical Officer	S Sale	2021-06-18	2021-06-22	3,728	$29.43	$109.7K	137,102	SEC↗
Lefebvre Eric	Chief Medical Officer	S Sale	2021-06-18	2021-06-22	22	$30.23	$665	137,080	SEC↗
Lefebvre Eric	Chief Medical Officer	S Sale	2021-06-18	2021-06-22	8,750	$28.62	$250.4K	140,830	SEC↗