Open-mkt buys · 90d
$417.4K
4 trades · 1 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$417.4K
Insiders on file
38
Daily buy vs sell · 90 days
■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Seidl Randy | Chief Executive Officer, Director | 14 | $720.3K | $0 | 2026-08-19 |
| Reardon Robert | Director | 1 | $0 | $0 | 2026-06-05 |
| Riley Christopher Michael | Director | 1 | $0 | $0 | 2026-06-05 |
| Steele Alexandra | Director | 1 | $0 | $0 | 2026-06-05 |
| Truong Oanh | Interim CFO | 1 | $0 | $0 | 2026-06-05 |
| You Harry L. | Director, 10% Owner | 3 | $0 | $0 | 2026-06-05 |
| Sylvester David C | Director | 1 | $0 | $0 | 2026-06-05 |
| DICKERSON LYMAN B | Director | 6 | $0 | $41.2K | 2026-06-05 |
| PEPERZAK MARCUS | Director | 1 | $0 | $0 | 2026-06-05 |
| DACIER PAUL T | 10% Owner | 2 | $250.1K | $0 | 2025-02-06 |
| Atkisson Erik | General Counsel and CCO | 5 | $0 | $0 | 2024-01-26 |
| Vellanki Avanish | President and CEO | 19 | $57.3K | $0 | 2024-01-26 |
| Doebele Robert | See Remarks | 25 | $0 | $0 | 2024-01-26 |
| Hrustanovic Gorjan | Director | 4 | $0 | $0 | 2024-01-26 |
| Wolff Stefani | Director | 6 | $0 | $0 | 2024-01-26 |
| Radovich Peter | Director | 9 | $0 | $0 | 2024-01-26 |
| Davis Aaron I. | Director, 10% Owner | 14 | $27.85M | $0 | 2024-01-26 |
| Nguyen Tran | Director | 6 | $0 | $0 | 2024-01-26 |
| BERGER FRANKLIN M | Director | 17 | $3.41M | $0 | 2024-01-26 |
| TANG CAPITAL PARTNERS LP | 10% Owner | 4 | $0 | $209.4K | 2024-01-26 |
| BIOTECHNOLOGY VALUE FUND II LP | Director | 8 | $0 | $0 | 2024-01-26 |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | 14 | $1.44M | $0 | 2023-10-13 |
| Bruce Josephine | Principal Fin. & Acc. Officer | 1 | $0 | $0 | 2023-08-09 |
| Boxer Capital, LLC | Director | 1 | $0 | $1.24M | 2023-05-22 |
| Cabatuan Nelson | VP of Finance & Admin | 3 | $0 | $0 | 2023-02-15 |
| BRYCE RICHARD PAUL | Chief Medical Officer | 2 | $0 | $0 | 2023-02-15 |
| BVF II GP LLC | Director | 3 | $9.97M | $0 | 2022-11-08 |
| BVF INC/IL | 10% Owner | 4 | $6.69M | $0 | 2022-01-07 |
| EDELMAN JOSEPH | 10% Owner | 7 | $0 | $667.5K | 2021-10-12 |
| BVF GP HOLDINGS LLC | Other | 15 | $25.73M | $0 | 2021-09-21 |
| BIOTECHNOLOGY VALUE FUND L P | Other | 6 | $9.08M | $0 | 2021-07-06 |
| Biotechnology Value Trading Fund OS LP | Other | 6 | $1.97M | $0 | 2021-05-24 |
| BVF I GP LLC | Other | 6 | $3.46M | $0 | 2021-05-19 |
| BVF Partners OS Ltd. | Other | 3 | $827.1K | $0 | 2021-05-13 |
| Chen Bihua | Director | 3 | $7.65M | $0 | 2021-04-27 |
| Boxer Asset Management Inc. | 10% Owner | 5 | $19.85M | $0 | 2021-04-27 |
| PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | 10% Owner | 5 | $9.35M | $0 | 2021-04-27 |
| LAMPERT MARK N | Other | 27 | $0 | $0 | 2021-04-26 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Seidl Randy | Chief Executive Officer | P Buy | 2026-08-19 | 2026-08-20 | 110,000 | $0.95 | $104.5K | 754,834 | SEC↗ |
| Seidl Randy | Chief Executive Officer | P Buy | 2026-08-19 | 2026-08-21 | 110,000 | $0.95 | $104.5K | 754,834 | SEC↗ |
| Seidl Randy | Chief Executive Officer, Dir | P Buy | 2026-08-19 | 2026-08-20 | 110,000 | $0.95 | $104.2K | 754,834 | SEC↗ |
| Seidl Randy | Chief Executive Officer, Dir | P Buy | 2026-08-19 | 2026-08-21 | 110,000 | $0.95 | $104.2K | 754,834 | SEC↗ |
| You Harry L. | Director, 10% Owner | A Award | 2026-06-05 | 2026-06-09 | 1,612,903 | — | $0 | 1,612,903 | SEC↗ |
| PEPERZAK MARCUS | Director | A Award | 2026-06-05 | 2026-06-09 | 80,000 | — | $0 | 80,000 | SEC↗ |
| Truong Oanh | Interim CFO | A Award | 2026-06-05 | 2026-06-09 | 50,000 | — | $0 | 50,000 | SEC↗ |
| Reardon Robert | Director | A Award | 2026-06-05 | 2026-06-09 | 80,000 | — | $0 | 80,000 | SEC↗ |
| DICKERSON LYMAN B | Director | A Award | 2026-06-05 | 2026-06-09 | 80,000 | — | $0 | 90,247 | SEC↗ |
| Steele Alexandra | Director | A Award | 2026-06-05 | 2026-06-09 | 80,000 | — | $0 | 80,000 | SEC↗ |
| Sylvester David C | Director | A Award | 2026-06-05 | 2026-06-09 | 40,000 | — | $0 | 40,000 | SEC↗ |
| Riley Christopher Michael | Director | A Award | 2026-06-05 | 2026-06-09 | 50,000 | — | $0 | 50,000 | SEC↗ |
| Seidl Randy | Chief Executive Officer | P Buy | 2026-05-22 | 2026-08-12 | 4,000 | $2.58 | $10.3K | 644,834 | SEC↗ |
| Seidl Randy | Chief Executive Officer, Dir | P Buy | 2026-05-22 | 2026-08-12 | 4,000 | $2.58 | $10.3K | 644,834 | SEC↗ |
| Seidl Randy | Chief Executive Officer | P Buy | 2026-05-21 | 2026-08-12 | 30,000 | $2.53 | $75.9K | 640,834 | SEC↗ |
| Seidl Randy | Chief Executive Officer, Dir | P Buy | 2026-05-21 | 2026-08-12 | 30,000 | $2.53 | $75.9K | 640,834 | SEC↗ |
| Seidl Randy | Chief Executive Officer | P Buy | 2026-05-20 | 2026-08-12 | 8,514 | $1.73 | $14.7K | 610,834 | SEC↗ |
| Seidl Randy | Chief Executive Officer, Dir | P Buy | 2026-05-20 | 2026-08-12 | 8,514 | $1.73 | $14.7K | 610,834 | SEC↗ |
| DICKERSON LYMAN B | Director | S Sale | 2025-09-12 | 2025-09-17 | 4,787 | $5.78 | $27.7K | 10,247 | SEC↗ |
| DICKERSON LYMAN B | Director | S Sale | 2025-09-11 | 2025-09-17 | 398 | $5.80 | $2.3K | 15,034 | SEC↗ |
| DICKERSON LYMAN B | Director | S Sale | 2025-09-10 | 2025-09-17 | 215 | $5.55 | $1.2K | 15,432 | SEC↗ |
| DICKERSON LYMAN B | Director | S Sale | 2025-09-09 | 2025-09-17 | 1,917 | $5.24 | $10.0K | 15,647 | SEC↗ |
| Seidl Randy | Chief Executive Officer | A Award | 2025-09-05 | 2025-09-09 | 602,320 | — | $0 | 602,320 | SEC↗ |
| Seidl Randy | Chief Executive Officer | P Buy | 2025-05-22 | 2026-05-22 | 4,000 | $2.58 | $10.3K | 644,834 | SEC↗ |
| Seidl Randy | Chief Executive Officer | P Buy | 2025-05-21 | 2026-05-22 | 30,000 | $2.53 | $75.9K | 640,834 | SEC↗ |
| Seidl Randy | Chief Executive Officer | P Buy | 2025-05-20 | 2026-05-22 | 8,514 | $1.73 | $14.7K | 610,834 | SEC↗ |
| DACIER PAUL T | 10% Owner | P Buy | 2025-02-06 | 2025-02-10 | 13,173 | $11.39 | $150.0K | 13,173 | SEC↗ |
| You Harry L. | Director, 10% Owner | A Award | 2025-01-29 | 2025-01-31 | 43,910 | $11.39 | $500.1K | 237,956 | SEC↗ |
| You Harry L. | Director, 10% Owner | A Award | 2024-12-31 | 2025-01-03 | 564,375 | — | $0 | 564,375 | SEC↗ |
| DICKERSON LYMAN B | Director | A Award | 2024-12-31 | 2024-12-31 | 17,564 | $11.39 | $200.1K | 17,564 | SEC↗ |
| DACIER PAUL T | 10% Owner | P Buy | 2024-12-31 | 2024-12-31 | 8,782 | $11.39 | $100.0K | 1,848,104 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | D To issuer deriv | 2024-01-26 | 2024-01-26 | 304,485 | — | $0 | 0 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | D To issuer deriv | 2024-01-26 | 2024-01-26 | 266,500 | — | $0 | 0 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | D To issuer deriv | 2024-01-26 | 2024-01-26 | 14,115 | — | $0 | 0 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | D To issuer deriv | 2024-01-26 | 2024-01-26 | 152,150 | — | $0 | 0 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | D To issuer deriv | 2024-01-26 | 2024-01-26 | 133,250 | — | $0 | 0 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | D To issuer deriv | 2024-01-26 | 2024-01-26 | 31,832 | — | $0 | 0 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | D To issuer deriv | 2024-01-26 | 2024-01-26 | 30,150 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | D To issuer deriv | 2024-01-26 | 2024-01-26 | 59,642 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | D To issuer deriv | 2024-01-26 | 2024-01-26 | 1,981 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | D To issuer deriv | 2024-01-26 | 2024-01-26 | 9,260 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | D To issuer deriv | 2024-01-26 | 2024-01-26 | 49,700 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | D To issuer deriv | 2024-01-26 | 2024-01-26 | 99,400 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | D To issuer deriv | 2024-01-26 | 2024-01-26 | 9,260 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | D To issuer deriv | 2024-01-26 | 2024-01-26 | 112,206 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | D To issuer deriv | 2024-01-26 | 2024-01-26 | 13,890 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | D To issuer deriv | 2024-01-26 | 2024-01-26 | 5,000 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | D To issuer deriv | 2024-01-26 | 2024-01-26 | 12,358 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | D To issuer deriv | 2024-01-26 | 2024-01-26 | 90,620 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | D To issuer deriv | 2024-01-26 | 2024-01-26 | 11,119 | — | $0 | 0 | SEC↗ |
| Atkisson Erik | General Counsel and CCO | D To issuer deriv | 2024-01-26 | 2024-01-26 | 82,882 | — | $0 | 0 | SEC↗ |
| Atkisson Erik | General Counsel and CCO | D To issuer deriv | 2024-01-26 | 2024-01-26 | 37,118 | — | $0 | 0 | SEC↗ |
| Atkisson Erik | General Counsel and CCO | D To issuer deriv | 2024-01-26 | 2024-01-26 | 60,251 | — | $0 | 0 | SEC↗ |
| BERGER FRANKLIN M | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 35,000 | — | $0 | 0 | SEC↗ |
| BERGER FRANKLIN M | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 24,000 | — | $0 | 0 | SEC↗ |
| BERGER FRANKLIN M | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 20,000 | — | $0 | 0 | SEC↗ |
| Davis Aaron I. | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 35,000 | — | $0 | 0 | SEC↗ |
| Davis Aaron I. | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 20,000 | — | $0 | 0 | SEC↗ |
| Hrustanovic Gorjan | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 35,000 | — | $0 | 0 | SEC↗ |
| Hrustanovic Gorjan | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 20,000 | — | $0 | 0 | SEC↗ |
| Nguyen Tran | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 20,000 | — | $0 | 0 | SEC↗ |
| Nguyen Tran | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 35,000 | — | $0 | 0 | SEC↗ |
| Nguyen Tran | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 13,890 | — | $0 | 0 | SEC↗ |
| Nguyen Tran | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 42,596 | — | $0 | 0 | SEC↗ |
| Radovich Peter | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 42,596 | — | $0 | 0 | SEC↗ |
| Radovich Peter | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 20,000 | — | $0 | 0 | SEC↗ |
| Radovich Peter | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 13,890 | — | $0 | 0 | SEC↗ |
| Radovich Peter | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 35,000 | — | $0 | 0 | SEC↗ |
| Wolff Stefani | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 24,000 | — | $0 | 0 | SEC↗ |
| Wolff Stefani | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 35,000 | — | $0 | 0 | SEC↗ |
| Wolff Stefani | Director | D To issuer deriv | 2024-01-26 | 2024-01-26 | 20,000 | — | $0 | 0 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND II LP | Director | D To issuer deriv | 2024-01-26 | 2024-01-29 | 20,000 | — | $0 | 0 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND II LP | Director | D To issuer deriv | 2024-01-26 | 2024-01-29 | 35,000 | — | $0 | 0 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | U Tender | 2024-01-26 | 2024-01-26 | 2,550,910 | — | $0 | 0 | SEC↗ |
| Doebele Robert | See Remarks | U Tender | 2024-01-26 | 2024-01-26 | 476,827 | — | $0 | 0 | SEC↗ |
| BERGER FRANKLIN M | Director | U Tender | 2024-01-26 | 2024-01-26 | 1,005,207 | — | $0 | 0 | SEC↗ |
| Davis Aaron I. | Director | U Tender | 2024-01-26 | 2024-01-26 | 79,726 | — | $0 | 0 | SEC↗ |
| Radovich Peter | Director | U Tender | 2024-01-26 | 2024-01-26 | 8,796 | — | $0 | 0 | SEC↗ |
| TANG CAPITAL PARTNERS LP | 10% Owner | U Tender | 2024-01-26 | 2024-02-02 | 3,850,513 | — | $0 | 0 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND II LP | Director | U Tender | 2024-01-25 | 2024-01-29 | 185,388 | — | $0 | 0 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND II LP | Director | U Tender | 2024-01-25 | 2024-01-29 | 341,547 | — | $0 | 0 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND II LP | Director | U Tender | 2024-01-25 | 2024-01-29 | 1,734,960 | — | $0 | 0 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND II LP | Director | U Tender | 2024-01-25 | 2024-01-29 | 2,076,085 | — | $0 | 0 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND II LP | Director | U Tender | 2024-01-25 | 2024-01-29 | 2,870,985 | — | $0 | 0 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND II LP | Director | U Tender | 2024-01-25 | 2024-01-29 | 1,367,838 | — | $0 | 0 | SEC↗ |
| TANG CAPITAL PARTNERS LP | 10% Owner | S Sale | 2023-12-18 | 2023-12-18 | 40,132 | $1.21 | $48.6K | 3,850,513 | SEC↗ |
| TANG CAPITAL PARTNERS LP | 10% Owner | S Sale | 2023-12-15 | 2023-12-18 | 109,435 | $1.20 | $131.3K | 3,890,645 | SEC↗ |
| TANG CAPITAL PARTNERS LP | 10% Owner | S Sale | 2023-12-14 | 2023-12-18 | 24,406 | $1.21 | $29.5K | 4,000,080 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-10-13 | 2023-10-13 | 47,486 | $0.99 | $47.0K | 3,940,341 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-10-13 | 2023-10-13 | 84,145 | $0.99 | $83.3K | 4,024,486 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-10-12 | 2023-10-13 | 52,514 | $0.98 | $51.5K | 3,892,855 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-10-12 | 2023-10-13 | 25,188 | $0.98 | $24.7K | 3,840,341 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-10-11 | 2023-10-13 | 74,812 | $0.97 | $72.6K | 3,815,153 | SEC↗ |
| Bruce Josephine | Principal Fin. & Acc. Office | A Award deriv | 2023-08-09 | 2023-08-11 | 10,800 | — | $0 | 10,800 | SEC↗ |
| Atkisson Erik | General Counsel and CCO | A Award deriv | 2023-08-09 | 2023-08-11 | 60,251 | — | $0 | 60,251 | SEC↗ |
| Davis Aaron I. | Director | A Award deriv | 2023-08-09 | 2023-08-11 | 35,000 | — | $0 | 35,000 | SEC↗ |
| Hrustanovic Gorjan | Director | A Award deriv | 2023-08-09 | 2023-08-11 | 35,000 | — | $0 | 35,000 | SEC↗ |
| Wolff Stefani | Director | A Award deriv | 2023-08-09 | 2023-08-11 | 35,000 | — | $0 | 35,000 | SEC↗ |
| Nguyen Tran | Director | A Award deriv | 2023-08-09 | 2023-08-11 | 35,000 | — | $0 | 35,000 | SEC↗ |
| Radovich Peter | Director | A Award deriv | 2023-08-09 | 2023-08-11 | 35,000 | — | $0 | 35,000 | SEC↗ |
| BERGER FRANKLIN M | Director | A Award deriv | 2023-08-09 | 2023-08-11 | 35,000 | — | $0 | 35,000 | SEC↗ |
| Doebele Robert | See Remarks | A Award deriv | 2023-08-09 | 2023-08-11 | 99,400 | — | $0 | 99,400 | SEC↗ |
| Doebele Robert | See Remarks | A Award deriv | 2023-08-09 | 2023-08-11 | 49,700 | — | $0 | 49,700 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | A Award deriv | 2023-08-09 | 2023-08-11 | 133,250 | — | $0 | 133,250 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | A Award deriv | 2023-08-09 | 2023-08-11 | 266,500 | — | $0 | 266,500 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-06-01 | 2023-06-01 | 240,341 | $1.12 | $269.2K | 3,740,341 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-06-01 | 2023-06-01 | 92,984 | $1.09 | $101.4K | 3,500,000 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-05-31 | 2023-06-01 | 5,000 | $1.10 | $5.5K | 3,407,016 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-05-31 | 2023-06-01 | 161,180 | $1.08 | $174.1K | 3,402,016 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-05-30 | 2023-06-01 | 32,890 | $1.06 | $34.9K | 3,232,890 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-05-30 | 2023-06-01 | 200,000 | $1.00 | $200.0K | 3,200,000 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-05-30 | 2023-06-01 | 347,932 | $1.05 | $365.3K | 3,000,000 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-05-30 | 2023-06-01 | 5,930 | $1.06 | $6.3K | 3,240,836 | SEC↗ |
| TANG CAPITAL MANAGEMENT LLC | 10% Owner | P Buy | 2023-05-30 | 2023-06-01 | 2,016 | $1.08 | $2.2K | 3,234,906 | SEC↗ |
| Boxer Capital, LLC | Director | S Sale | 2023-05-22 | 2023-05-24 | 995,000 | $1.25 | $1.24M | 1,152,212 | SEC↗ |
| Atkisson Erik | General Counsel and CCO | A Award deriv | 2023-03-02 | 2023-03-03 | 120,000 | — | $0 | 120,000 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | A Award deriv | 2023-02-15 | 2023-02-17 | 318,600 | — | $0 | 318,600 | SEC↗ |
| Doebele Robert | See Remarks | A Award deriv | 2023-02-15 | 2023-02-17 | 123,325 | — | $0 | 123,325 | SEC↗ |
| BRYCE RICHARD PAUL | Chief Medical Officer | A Award deriv | 2023-02-15 | 2023-02-17 | 110,000 | — | $0 | 110,000 | SEC↗ |
| Cabatuan Nelson | VP of Finance & Admin | A Award deriv | 2023-02-15 | 2023-02-17 | 65,325 | — | $0 | 65,325 | SEC↗ |
| BERGER FRANKLIN M | Director | P Buy | 2022-11-22 | 2022-11-23 | 77,000 | $8.27 | $636.8K | 1,005,207 | SEC↗ |
| BERGER FRANKLIN M | Director | P Buy | 2022-11-21 | 2022-11-23 | 45,000 | $7.80 | $351.0K | 928,207 | SEC↗ |
| BVF II GP LLC | Director | P Buy | 2022-11-08 | 2022-11-10 | 970,171 | $5.83 | $5.66M | 2,870,985 | SEC↗ |
| BVF II GP LLC | Director | P Buy | 2022-11-08 | 2022-11-10 | 54,857 | $5.83 | $319.8K | 341,547 | SEC↗ |
| BVF II GP LLC | Director | P Buy | 2022-11-08 | 2022-11-10 | 685,330 | $5.83 | $4.00M | 2,076,085 | SEC↗ |
| BERGER FRANKLIN M | Director | P Buy | 2022-11-08 | 2022-11-14 | 42,881 | $5.83 | $250.0K | 883,207 | SEC↗ |
| Davis Aaron I. | Director | P Buy deriv | 2022-11-04 | 2022-11-08 | 400,000 | $5.83 | $2.33M | 3,422,489 | SEC↗ |
| Davis Aaron I. | Director | P Buy | 2022-11-04 | 2022-11-08 | 972,212 | $5.83 | $5.67M | 2,147,212 | SEC↗ |
| Doebele Robert | See Remarks | M Exercise deriv | 2022-07-06 | 2022-07-07 | 3,890 | — | $0 | 5,000 | SEC↗ |
| Doebele Robert | See Remarks | M Exercise | 2022-07-06 | 2022-07-07 | 3,890 | $3.95 | $15.4K | 476,827 | SEC↗ |
| Hrustanovic Gorjan | Director | A Award deriv | 2022-06-01 | 2022-08-19 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Radovich Peter | Director | A Award deriv | 2022-06-01 | 2022-08-19 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Wolff Stefani | Director | A Award deriv | 2022-06-01 | 2022-08-19 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Nguyen Tran | Director | A Award deriv | 2022-06-01 | 2022-08-19 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Davis Aaron I. | Director | A Award deriv | 2022-06-01 | 2022-08-19 | 20,000 | — | $0 | 20,000 | SEC↗ |
| BERGER FRANKLIN M | Director | A Award deriv | 2022-06-01 | 2022-08-19 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | P Buy | 2022-06-01 | 2022-06-02 | 25,000 | $2.29 | $57.3K | 2,471,627 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | G Gift | 2022-04-14 | 2022-04-15 | 59,618 | — | $0 | 2,446,627 | SEC↗ |
| Vellanki Avanish | Chairman and CEO | G Gift | 2022-04-14 | 2022-04-15 | 59,618 | — | $0 | 79,283 | SEC↗ |
| Doebele Robert | See Remarks | M Exercise deriv | 2022-04-13 | 2022-04-15 | 3,000 | — | $0 | 8,890 | SEC↗ |
| Doebele Robert | See Remarks | M Exercise | 2022-04-13 | 2022-04-15 | 3,000 | $3.95 | $11.8K | 472,937 | SEC↗ |
| Doebele Robert | See Remarks | M Exercise deriv | 2022-03-31 | 2022-04-04 | 2,000 | — | $0 | 11,890 | SEC↗ |
| Doebele Robert | See Remarks | M Exercise | 2022-03-31 | 2022-04-04 | 2,000 | $3.95 | $7.9K | 469,937 | SEC↗ |
| Vellanki Avanish | President and CEO | M Exercise deriv | 2022-03-11 | 2022-03-15 | 14,468 | — | $0 | 31,832 | SEC↗ |
| Vellanki Avanish | President and CEO | M Exercise | 2022-03-11 | 2022-03-15 | 14,468 | $4.00 | $57.9K | 2,837,009 | SEC↗ |
| Vellanki Avanish | President and CEO | A Award deriv | 2022-02-02 | 2022-02-04 | 182,300 | — | $0 | 182,300 | SEC↗ |
| Doebele Robert | EVP, Chief Scientific Office | A Award deriv | 2022-01-07 | 2022-02-04 | 72,000 | — | $0 | 72,000 | SEC↗ |
| BRYCE RICHARD PAUL | Chief Medical Officer | A Award deriv | 2022-01-07 | 2022-02-04 | 53,064 | — | $0 | 53,064 | SEC↗ |
| Cabatuan Nelson | See Remarks | A Award deriv | 2022-01-07 | 2022-02-04 | 32,000 | — | $0 | 32,000 | SEC↗ |
| BVF INC/IL | 10% Owner | P Buy | 2022-01-07 | 2022-01-10 | 14,806 | $12.00 | $177.7K | 185,388 | SEC↗ |
| BVF INC/IL | 10% Owner | P Buy | 2022-01-07 | 2022-01-10 | 226,079 | $12.00 | $2.71M | 1,367,838 | SEC↗ |
| BVF INC/IL | 10% Owner | P Buy | 2022-01-07 | 2022-01-10 | 255,500 | $12.00 | $3.07M | 1,734,960 | SEC↗ |
| BVF INC/IL | 10% Owner | P Buy | 2022-01-06 | 2022-01-10 | 61,343 | $12.00 | $736.1K | 1,141,759 | SEC↗ |
| EDELMAN JOSEPH | 10% Owner | S Sale | 2021-10-12 | 2021-10-13 | 7,306 | $13.40 | $97.9K | 2,487,019 | SEC↗ |
| EDELMAN JOSEPH | 10% Owner | S Sale | 2021-10-11 | 2021-10-13 | 9,351 | $13.15 | $123.0K | 2,494,325 | SEC↗ |
| EDELMAN JOSEPH | 10% Owner | S Sale | 2021-10-11 | 2021-10-13 | 12,475 | $12.03 | $150.1K | 2,503,676 | SEC↗ |
| EDELMAN JOSEPH | 10% Owner | S Sale | 2021-10-08 | 2021-10-13 | 2,462 | $13.66 | $33.6K | 2,516,151 | SEC↗ |
| EDELMAN JOSEPH | 10% Owner | S Sale | 2021-10-08 | 2021-10-13 | 5,038 | $12.90 | $65.0K | 2,518,613 | SEC↗ |
| EDELMAN JOSEPH | 10% Owner | S Sale | 2021-10-07 | 2021-10-13 | 286 | $15.05 | $4.3K | 2,523,651 | SEC↗ |
| EDELMAN JOSEPH | 10% Owner | S Sale | 2021-10-07 | 2021-10-13 | 13,082 | $14.80 | $193.6K | 2,523,937 | SEC↗ |
| BERGER FRANKLIN M | Director | P Buy | 2021-09-21 | 2021-09-23 | 3,786 | $14.30 | $54.1K | 840,326 | SEC↗ |
| BVF GP HOLDINGS LLC | 10% Owner | P Buy | 2021-09-21 | 2021-09-23 | 4,102 | $13.94 | $57.2K | 1,080,416 | SEC↗ |
| BVF GP HOLDINGS LLC | 10% Owner | P Buy | 2021-09-21 | 2021-09-23 | 6,341 | $13.94 | $88.4K | 1,479,460 | SEC↗ |
| BVF GP HOLDINGS LLC | 10% Owner | P Buy | 2021-09-21 | 2021-09-23 | 590 | $13.94 | $8.2K | 170,582 | SEC↗ |
| BVF GP HOLDINGS LLC | 10% Owner | P Buy | 2021-09-13 | 2021-09-15 | 158,511 | $16.49 | $2.61M | 1,076,314 | SEC↗ |
| BVF GP HOLDINGS LLC | 10% Owner | P Buy | 2021-09-13 | 2021-09-15 | 20,512 | $16.49 | $338.2K | 169,992 | SEC↗ |
| BVF GP HOLDINGS LLC | 10% Owner | P Buy | 2021-09-13 | 2021-09-15 | 213,246 | $16.49 | $3.52M | 1,473,119 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND L P | Other | P Buy | 2021-07-06 | 2021-07-06 | 16,980 | $15.25 | $258.9K | 149,480 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND L P | Other | P Buy | 2021-07-06 | 2021-07-06 | 146,116 | $15.25 | $2.23M | 1,259,873 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND L P | Other | P Buy | 2021-07-06 | 2021-07-06 | 106,627 | $15.25 | $1.63M | 917,803 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND L P | Other | P Buy | 2021-07-01 | 2021-07-06 | 20,018 | $15.65 | $313.3K | 132,500 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND L P | Other | P Buy | 2021-07-01 | 2021-07-06 | 172,457 | $15.65 | $2.70M | 1,113,757 | SEC↗ |
| BIOTECHNOLOGY VALUE FUND L P | Other | P Buy | 2021-07-01 | 2021-07-06 | 124,804 | $15.65 | $1.95M | 811,176 | SEC↗ |
| Biotechnology Value Trading Fu | Other | P Buy | 2021-05-24 | 2021-05-25 | 719 | $15.90 | $11.4K | 941,300 | SEC↗ |
| Biotechnology Value Trading Fu | Other | P Buy | 2021-05-24 | 2021-05-25 | 129 | $15.90 | $2.1K | 112,482 | SEC↗ |
| Biotechnology Value Trading Fu | Other | P Buy | 2021-05-24 | 2021-05-25 | 513 | $15.90 | $8.2K | 686,372 | SEC↗ |
| Biotechnology Value Trading Fu | Other | P Buy | 2021-05-21 | 2021-05-25 | 66,242 | $15.94 | $1.06M | 940,581 | SEC↗ |
| Biotechnology Value Trading Fu | Other | P Buy | 2021-05-21 | 2021-05-25 | 48,152 | $15.94 | $767.5K | 685,859 | SEC↗ |
| Biotechnology Value Trading Fu | Other | P Buy | 2021-05-21 | 2021-05-25 | 7,592 | $15.94 | $121.0K | 112,353 | SEC↗ |
| BVF I GP LLC | Other | P Buy | 2021-05-19 | 2021-05-20 | 6,962 | $15.88 | $110.6K | 637,707 | SEC↗ |
| BVF I GP LLC | Other | P Buy | 2021-05-19 | 2021-05-20 | 1,115 | $15.88 | $17.7K | 104,761 | SEC↗ |
| BVF I GP LLC | Other | P Buy | 2021-05-19 | 2021-05-20 | 9,191 | $15.88 | $146.0K | 874,339 | SEC↗ |
| BVF I GP LLC | Other | P Buy | 2021-05-18 | 2021-05-20 | 75,640 | $16.65 | $1.26M | 630,745 | SEC↗ |
| BVF I GP LLC | Other | P Buy | 2021-05-18 | 2021-05-20 | 11,946 | $16.65 | $198.9K | 103,646 | SEC↗ |
| BVF I GP LLC | Other | P Buy | 2021-05-18 | 2021-05-20 | 103,611 | $16.65 | $1.73M | 865,148 | SEC↗ |
| Wolff Stefani | Director | A Award deriv | 2021-05-14 | 2021-05-18 | 24,000 | — | $0 | 24,000 | SEC↗ |
| BERGER FRANKLIN M | Director | A Award deriv | 2021-05-14 | 2021-05-18 | 24,000 | — | $0 | 24,000 | SEC↗ |
| BVF Partners OS Ltd. | Other | P Buy | 2021-05-13 | 2021-05-17 | 22,721 | $14.26 | $324.0K | 555,105 | SEC↗ |
| BVF Partners OS Ltd. | Other | P Buy | 2021-05-13 | 2021-05-17 | 3,474 | $14.26 | $49.5K | 91,700 | SEC↗ |
| BVF Partners OS Ltd. | Other | P Buy | 2021-05-13 | 2021-05-17 | 31,805 | $14.26 | $453.5K | 761,537 | SEC↗ |
| Cabatuan Nelson | See Remarks | A Award deriv | 2021-05-12 | 2021-05-14 | 6,000 | — | $0 | 6,000 | SEC↗ |
| Vellanki Avanish | President and CEO | C Conversion deriv | 2021-04-27 | 2021-04-27 | 12,108 | — | $0 | 0 | SEC↗ |
| Doebele Robert | EVP, Chief Scientific Office | C Conversion deriv | 2021-04-27 | 2021-04-27 | 5,327 | — | $0 | 0 | SEC↗ |
| BERGER FRANKLIN M | Director | C Conversion deriv | 2021-04-27 | 2021-04-27 | 578,397 | — | $0 | 0 | SEC↗ |
| BERGER FRANKLIN M | Director | C Conversion deriv | 2021-04-27 | 2021-04-27 | 189,998 | — | $0 | 0 | SEC↗ |
| Radovich Peter | Director | C Conversion deriv | 2021-04-27 | 2021-04-27 | 9,500 | — | $0 | 0 | SEC↗ |
| Davis Aaron I. | Director, 10% Owner | C Conversion deriv | 2021-04-27 | 2021-04-27 | 86,097 | — | $0 | 0 | SEC↗ |
| Davis Aaron I. | Director, 10% Owner | C Conversion deriv | 2021-04-27 | 2021-04-27 | 3,263,986 | — | $0 | 0 | SEC↗ |
| Davis Aaron I. | Director, 10% Owner | C Conversion deriv | 2021-04-27 | 2021-04-27 | 79,726 | — | $0 | 79,726 | SEC↗ |
| Davis Aaron I. | Director, 10% Owner | C Conversion deriv | 2021-04-27 | 2021-04-27 | 3,022,489 | — | $0 | 3,022,489 | SEC↗ |
| Boxer Asset Management Inc. | 10% Owner | C Conversion deriv | 2021-04-27 | 2021-04-27 | 3,263,986 | — | $0 | 3,022,489 | SEC↗ |
| Boxer Asset Management Inc. | 10% Owner | C Conversion deriv | 2021-04-27 | 2021-04-27 | 3,022,489 | — | $0 | 79,726 | SEC↗ |
| PERCEPTIVE LIFE SCIENCES MASTE | 10% Owner | C Conversion deriv | 2021-04-27 | 2021-04-27 | 1,195,792 | — | $0 | 0 | SEC↗ |
| PERCEPTIVE LIFE SCIENCES MASTE | 10% Owner | C Conversion deriv | 2021-04-27 | 2021-04-27 | 949,992 | — | $0 | 0 | SEC↗ |
| Chen Bihua | Director | C Conversion deriv | 2021-04-27 | 2021-04-29 | 2,512,561 | — | $0 | 0 | SEC↗ |
| Vellanki Avanish | President and CEO | C Conversion | 2021-04-27 | 2021-04-27 | 11,212 | — | $0 | 2,372,541 | SEC↗ |
| Doebele Robert | EVP, Chief Scientific Office | C Conversion | 2021-04-27 | 2021-04-27 | 4,932 | — | $0 | 467,937 | SEC↗ |
| BERGER FRANKLIN M | Director | C Conversion | 2021-04-27 | 2021-04-27 | 175,939 | — | $0 | 300,939 | SEC↗ |
| BERGER FRANKLIN M | Director | C Conversion | 2021-04-27 | 2021-04-27 | 535,601 | — | $0 | 836,540 | SEC↗ |
| Radovich Peter | Director | C Conversion | 2021-04-27 | 2021-04-27 | 8,796 | — | $0 | 8,796 | SEC↗ |
| Davis Aaron I. | Director, 10% Owner | P Buy | 2021-04-27 | 2021-04-27 | 1,025,000 | $17.00 | $17.43M | 1,175,000 | SEC↗ |
| Boxer Asset Management Inc. | 10% Owner | P Buy | 2021-04-27 | 2021-04-27 | 1,025,000 | $17.00 | $17.43M | 1,175,000 | SEC↗ |
| PERCEPTIVE LIFE SCIENCES MASTE | 10% Owner | P Buy | 2021-04-27 | 2021-04-27 | 550,000 | $17.00 | $9.35M | 2,537,019 | SEC↗ |
| PERCEPTIVE LIFE SCIENCES MASTE | 10% Owner | C Conversion | 2021-04-27 | 2021-04-27 | 1,107,316 | — | $0 | 1,987,019 | SEC↗ |
| PERCEPTIVE LIFE SCIENCES MASTE | 10% Owner | C Conversion | 2021-04-27 | 2021-04-27 | 879,703 | — | $0 | 879,703 | SEC↗ |
| Chen Bihua | Director | P Buy | 2021-04-27 | 2021-04-29 | 450,000 | $17.00 | $7.65M | 2,776,657 | SEC↗ |
| Chen Bihua | Director | C Conversion | 2021-04-27 | 2021-04-29 | 2,326,657 | — | $0 | 2,326,657 | SEC↗ |
| LAMPERT MARK N | Other | A Award | 2021-04-26 | 2021-04-27 | 1,747 | $14.90 | $26.0K | 88,226 | SEC↗ |
| LAMPERT MARK N | Other | A Award | 2021-04-26 | 2021-04-27 | 10,876 | $14.90 | $162.1K | 532,384 | SEC↗ |
| LAMPERT MARK N | Other | A Award | 2021-04-26 | 2021-04-27 | 14,790 | $14.90 | $220.4K | 729,732 | SEC↗ |
| BVF GP HOLDINGS LLC | Other | P Buy | 2021-04-26 | 2021-05-17 | 10,876 | $14.90 | $162.1K | 532,384 | SEC↗ |
| BVF GP HOLDINGS LLC | Other | P Buy | 2021-04-26 | 2021-05-17 | 1,747 | $14.90 | $26.0K | 88,226 | SEC↗ |
| BVF GP HOLDINGS LLC | Other | P Buy | 2021-04-26 | 2021-05-17 | 14,790 | $14.90 | $220.4K | 729,732 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion deriv | 2021-04-23 | 2021-04-27 | 832,261 | — | $0 | 0 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion deriv | 2021-04-23 | 2021-04-27 | 115,293 | — | $0 | 832,261 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion deriv | 2021-04-23 | 2021-04-27 | 134,515 | — | $0 | 0 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion deriv | 2021-04-23 | 2021-04-27 | 837,397 | — | $0 | 0 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion deriv | 2021-04-23 | 2021-04-27 | 553,359 | — | $0 | 0 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion deriv | 2021-04-23 | 2021-04-27 | 84,350 | — | $0 | 553,359 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion deriv | 2021-04-23 | 2021-04-27 | 1,068,554 | — | $0 | 0 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion deriv | 2021-04-23 | 2021-04-27 | 17,390 | — | $0 | 152,176 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion deriv | 2021-04-23 | 2021-04-27 | 152,176 | — | $0 | 0 | SEC↗ |
| BERGER FRANKLIN M | Director | P Buy | 2021-04-23 | 2021-04-27 | 120,000 | $17.00 | $2.04M | 120,000 | SEC↗ |
| BERGER FRANKLIN M | Director | P Buy | 2021-04-23 | 2021-04-27 | 5,000 | $15.78 | $78.9K | 125,000 | SEC↗ |
| Davis Aaron I. | Director, 10% Owner | P Buy | 2021-04-23 | 2021-04-27 | 125,000 | $16.27 | $2.03M | 150,000 | SEC↗ |
| Davis Aaron I. | Director, 10% Owner | P Buy | 2021-04-23 | 2021-04-27 | 25,000 | $15.58 | $389.5K | 25,000 | SEC↗ |
| Boxer Asset Management Inc. | 10% Owner | P Buy | 2021-04-23 | 2021-04-27 | 125,000 | $16.27 | $2.03M | 150,000 | SEC↗ |
| Boxer Asset Management Inc. | 10% Owner | P Buy | 2021-04-23 | 2021-04-27 | 25,000 | $15.58 | $389.5K | 25,000 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion | 2021-04-23 | 2021-04-27 | 1,068,554 | — | $0 | 1,900,815 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion | 2021-04-23 | 2021-04-27 | 84,350 | — | $0 | 84,350 | SEC↗ |
| LAMPERT MARK N | Other | A Award | 2021-04-23 | 2021-04-27 | 398,300 | $17.00 | $6.77M | 482,650 | SEC↗ |
| LAMPERT MARK N | Other | A Award | 2021-04-23 | 2021-04-27 | 38,858 | $15.93 | $619.0K | 521,508 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion | 2021-04-23 | 2021-04-27 | 553,359 | — | $0 | 553,359 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion | 2021-04-23 | 2021-04-27 | 837,397 | — | $0 | 1,390,756 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion | 2021-04-23 | 2021-04-27 | 17,390 | — | $0 | 17,390 | SEC↗ |
| LAMPERT MARK N | Other | A Award | 2021-04-23 | 2021-04-27 | 62,948 | $17.00 | $1.07M | 80,338 | SEC↗ |
| LAMPERT MARK N | Other | A Award | 2021-04-23 | 2021-04-27 | 6,141 | $15.93 | $97.8K | 86,479 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion | 2021-04-23 | 2021-04-27 | 832,261 | — | $0 | 832,261 | SEC↗ |
| LAMPERT MARK N | Other | A Award | 2021-04-23 | 2021-04-27 | 53,303 | $15.93 | $849.1K | 714,942 | SEC↗ |
| LAMPERT MARK N | Other | A Award | 2021-04-23 | 2021-04-27 | 546,346 | $17.00 | $9.29M | 661,639 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion | 2021-04-23 | 2021-04-27 | 115,293 | — | $0 | 115,293 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion | 2021-04-23 | 2021-04-27 | 134,515 | — | $0 | 286,691 | SEC↗ |
| LAMPERT MARK N | Other | C Conversion | 2021-04-23 | 2021-04-27 | 152,176 | — | $0 | 152,176 | SEC↗ |
| BVF GP HOLDINGS LLC | Other | P Buy | 2021-04-23 | 2021-05-17 | 546,346 | $17.00 | $9.29M | 661,639 | SEC↗ |
| BVF GP HOLDINGS LLC | Other | P Buy | 2021-04-23 | 2021-05-17 | 53,303 | $15.93 | $849.1K | 714,942 | SEC↗ |
| BVF GP HOLDINGS LLC | Other | P Buy | 2021-04-23 | 2021-05-17 | 6,141 | $15.93 | $97.8K | 86,479 | SEC↗ |
| BVF GP HOLDINGS LLC | Other | P Buy | 2021-04-23 | 2021-05-17 | 62,948 | $17.00 | $1.07M | 80,338 | SEC↗ |
| BVF GP HOLDINGS LLC | Other | P Buy | 2021-04-23 | 2021-05-17 | 38,858 | $15.93 | $619.0K | 521,508 | SEC↗ |
| BVF GP HOLDINGS LLC | Other | P Buy | 2021-04-23 | 2021-05-17 | 398,300 | $17.00 | $6.77M | 482,650 | SEC↗ |