SAGE

Sage Therapeutics, Inc.CIK 1597553 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for SAGE PRO

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AI insights for SAGE

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Quirk Michael C.	See Remarks	11	$0	$0	2025-07-31
Shiferman Gregory L.	See Remarks	16	$0	$0	2025-07-31
Federer Jessica	Director	6	$0	$0	2025-07-31
Benecchi Christopher	Chief Operating Officer	23	$0	$0	2025-07-31
Barrett Elizabeth A.	Director	3	$0	$0	2025-07-31
Golumbeski George	Director	18	$251.6K	$0	2025-07-31
Germano Geno J	Director	12	$0	$0	2025-07-31
Greene Barry E	President and CEO	17	$2.02M	$0	2025-07-31
FRATES JAMES M	Director	34	$189.7K	$4.67M	2025-07-31
COLA MICHAEL F	Director	13	$0	$0	2025-07-31
Gault Laura	Chief Medical Officer	8	$0	$0	2025-02-13
Cook Anne Marie	Senior VP, General Counsel	32	$0	$2.49M	2024-08-05
IGUCHI KIMI	See Remarks	104	$116.7K	$11.95M	2024-08-05
Barrett Elizabeth	Director	11	$87.8K	$0	2024-06-10
JONAS JEFFREY M	See Remarks	105	$600.7K	$82.65M	2024-06-10
PAUL STEVEN M	Director	74	$180.0K	$36.16M	2024-01-03
STARR KEVIN P	Director, 10% Owner	45	$1.00M	$36.52M	2023-06-15
Robichaud Albert	Chief Scientific Officer	55	$1.68M	$14.37M	2023-02-13
Kanes Stephen	Chief Medical Officer	56	$54.0K	$14.50M	2021-10-19
Cloonan Michael	Chief Business Officer	12	$0	$4.38M	2021-02-10
Nayak Asha	Director	3	$0	$0	2019-06-05
Anderson Thomas	See Remarks	18	$108.0K	$1.39M	2017-02-06
Third Rock Ventures GP II, L.P.	10% Owner	7	$0	$26.56M	2016-08-19
PIEN HOWARD H	Director	2	$0	$0	2016-06-22
LEVIN MARK J	10% Owner	11	$0	$0	2015-11-12
NELSEN ROBERT	Director, 10% Owner	15	$0	$0	2015-11-09
TRV GP II, LLC	10% Owner	5	$0	$0	2015-06-19
BYBEE CLINTON	10% Owner	2	$0	$0	2015-06-18
Third Rock Ventures II, L.P.	10% Owner	6	$0	$0	2015-01-27
ARCH Venture Partners VII, LLC	10% Owner	6	$0	$0	2014-07-23
Bulley Michael D	SVP Research & Risk Management	1	$100.0K	$0	2012-11-01

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Greene Barry E	President and CEO	D To issuer deriv	2025-07-31	2025-07-31	174,000	—	$0	0	SEC↗
Shiferman Gregory L.	See Remarks	D To issuer deriv	2025-07-31	2025-07-31	10,000	—	$0	0	SEC↗
Shiferman Gregory L.	See Remarks	D To issuer deriv	2025-07-31	2025-07-31	28,000	—	$0	0	SEC↗
FRATES JAMES M	Director	D To issuer deriv	2025-07-31	2025-07-31	19,154	—	$0	0	SEC↗
FRATES JAMES M	Director	D To issuer deriv	2025-07-31	2025-07-31	21,500	—	$0	0	SEC↗
Germano Geno J	Director	D To issuer deriv	2025-07-31	2025-07-31	21,500	—	$0	0	SEC↗
Golumbeski George	Director	D To issuer deriv	2025-07-31	2025-07-31	13,593	—	$0	0	SEC↗
Golumbeski George	Director	D To issuer deriv	2025-07-31	2025-07-31	21,500	—	$0	0	SEC↗
Barrett Elizabeth A.	Director	D To issuer deriv	2025-07-31	2025-07-31	21,500	—	$0	0	SEC↗
COLA MICHAEL F	Director	D To issuer deriv	2025-07-31	2025-07-31	21,500	—	$0	0	SEC↗
Benecchi Christopher	Chief Operating Officer	D To issuer deriv	2025-07-31	2025-07-31	12,500	—	$0	0	SEC↗
Benecchi Christopher	Chief Operating Officer	D To issuer deriv	2025-07-31	2025-07-31	40,000	—	$0	0	SEC↗
Federer Jessica	Director	D To issuer deriv	2025-07-31	2025-07-31	21,500	—	$0	0	SEC↗
Quirk Michael C.	See Remarks	D To issuer deriv	2025-07-31	2025-07-31	4,000	—	$0	0	SEC↗
Quirk Michael C.	See Remarks	D To issuer deriv	2025-07-31	2025-07-31	36,000	—	$0	0	SEC↗
Greene Barry E	President and CEO	D To issuer	2025-07-31	2025-07-31	53,229	—	$0	0	SEC↗
Greene Barry E	President and CEO	U Tender	2025-07-31	2025-07-31	46,940	—	$0	0	SEC↗
Shiferman Gregory L.	See Remarks	D To issuer	2025-07-31	2025-07-31	23,735	—	$0	0	SEC↗
Shiferman Gregory L.	See Remarks	U Tender	2025-07-31	2025-07-31	7,215	—	$0	0	SEC↗
FRATES JAMES M	Director	U Tender	2025-07-31	2025-07-31	2,845	—	$0	0	SEC↗
Golumbeski George	Director	U Tender	2025-07-31	2025-07-31	8,000	—	$0	0	SEC↗
Barrett Elizabeth A.	Director	U Tender	2025-07-31	2025-07-31	3,000	—	$0	0	SEC↗
Benecchi Christopher	Chief Operating Officer	D To issuer	2025-07-31	2025-07-31	36,375	—	$0	0	SEC↗
Benecchi Christopher	Chief Operating Officer	D To issuer	2025-07-31	2025-07-31	28,053	—	$0	0	SEC↗
Quirk Michael C.	See Remarks	D To issuer	2025-07-31	2025-07-31	24,999	—	$0	0	SEC↗
Quirk Michael C.	See Remarks	D To issuer	2025-07-31	2025-07-31	7,962	—	$0	0	SEC↗
Shiferman Gregory L.	See Remarks	F Tax w/h	2025-06-24	2025-06-26	79	$9.22	$728	30,950	SEC↗
Quirk Michael C.	See Remarks	F Tax w/h	2025-06-24	2025-06-26	113	$9.22	$1.0K	30,461	SEC↗
Barrett Elizabeth A.	Director	A Award deriv	2025-06-11	2025-06-13	21,500	—	$0	21,500	SEC↗
COLA MICHAEL F	Director	A Award deriv	2025-06-11	2025-06-13	21,500	—	$0	21,500	SEC↗
Federer Jessica	Director	A Award deriv	2025-06-11	2025-06-13	21,500	—	$0	21,500	SEC↗
FRATES JAMES M	Director	A Award deriv	2025-06-11	2025-06-13	21,500	—	$0	21,500	SEC↗
Golumbeski George	Director	A Award deriv	2025-06-11	2025-06-13	21,500	—	$0	21,500	SEC↗
Germano Geno J	Director	A Award deriv	2025-06-11	2025-06-13	21,500	—	$0	21,500	SEC↗
Shiferman Gregory L.	See Remarks	F Tax w/h	2025-04-10	2025-04-11	176	$6.91	$1.2K	31,029	SEC↗
Shiferman Gregory L.	See Remarks	A Award	2025-04-10	2025-04-11	525	—	$0	31,205	SEC↗
Greene Barry E	President and CEO	A Award	2025-04-10	2025-04-11	19,964	—	$0	105,031	SEC↗
Greene Barry E	President and CEO	F Tax w/h	2025-04-10	2025-04-11	4,862	$6.91	$33.6K	100,169	SEC↗
Quirk Michael C.	See Remarks	A Award	2025-04-10	2025-04-11	1,269	—	$0	30,998	SEC↗
Quirk Michael C.	See Remarks	F Tax w/h	2025-04-10	2025-04-11	312	$6.91	$2.2K	29,729	SEC↗
Quirk Michael C.	See Remarks	A Award	2025-04-10	2025-04-11	933	—	$0	30,041	SEC↗
Quirk Michael C.	See Remarks	F Tax w/h	2025-04-10	2025-04-11	424	$6.91	$2.9K	30,574	SEC↗
Benecchi Christopher	Chief Operating Officer	A Award	2025-04-10	2025-04-11	3,255	—	$0	47,170	SEC↗
Benecchi Christopher	Chief Operating Officer	A Award	2025-04-10	2025-04-11	2,712	—	$0	49,089	SEC↗
Benecchi Christopher	Chief Operating Officer	F Tax w/h	2025-04-10	2025-04-11	661	$6.91	$4.6K	48,428	SEC↗
Benecchi Christopher	Chief Operating Officer	F Tax w/h	2025-04-10	2025-04-11	793	$6.91	$5.5K	46,377	SEC↗
Quirk Michael C.	See Remarks	A Award deriv	2025-04-01	2025-04-02	4,000	—	$0	4,000	SEC↗
Quirk Michael C.	See Remarks	A Award	2025-04-01	2025-04-02	2,000	—	$0	29,108	SEC↗
Shiferman Gregory L.	See Remarks	F Tax w/h	2025-03-24	2025-03-26	79	$8.21	$649	30,680	SEC↗
Shiferman Gregory L.	See Remarks	F Tax w/h	2025-02-24	2025-02-25	2,502	$7.49	$18.7K	30,759	SEC↗
Shiferman Gregory L.	See Remarks	F Tax w/h	2025-02-13	2025-02-14	376	$7.18	$2.7K	33,512	SEC↗
Shiferman Gregory L.	See Remarks	F Tax w/h	2025-02-13	2025-02-14	251	$7.18	$1.8K	33,261	SEC↗
Gault Laura	Chief Medical Officer	F Tax w/h	2025-02-13	2025-02-14	685	$7.18	$4.9K	34,649	SEC↗
Benecchi Christopher	Chief Operating Officer	F Tax w/h	2025-02-13	2025-02-14	822	$7.18	$5.9K	43,915	SEC↗
Benecchi Christopher	Chief Operating Officer	A Award deriv	2025-01-16	2025-01-21	40,000	—	$0	40,000	SEC↗
Greene Barry E	President and CEO	A Award deriv	2025-01-16	2025-01-21	174,000	—	$0	174,000	SEC↗
Shiferman Gregory L.	See Remarks	A Award deriv	2025-01-16	2025-01-21	28,000	—	$0	28,000	SEC↗
Benecchi Christopher	Chief Operating Officer	A Award	2025-01-16	2025-01-21	20,000	—	$0	44,737	SEC↗
Gault Laura	Chief Medical Officer	A Award	2025-01-16	2025-01-21	24,000	—	$0	35,334	SEC↗
Shiferman Gregory L.	See Remarks	A Award	2025-01-16	2025-01-21	14,000	—	$0	33,888	SEC↗
FRATES JAMES M	Director	A Award deriv	2025-01-03	2025-01-06	19,154	—	$0	19,154	SEC↗
Golumbeski George	Director	A Award deriv	2025-01-03	2025-01-06	13,593	—	$0	13,593	SEC↗
Shiferman Gregory L.	See Remarks	F Tax w/h	2024-12-24	2024-12-27	79	$5.48	$433	19,888	SEC↗
Shiferman Gregory L.	See Remarks	A Award deriv	2024-11-01	2024-11-01	10,000	—	$0	10,000	SEC↗
Benecchi Christopher	Chief Operating Officer	A Award deriv	2024-11-01	2024-11-14	12,500	—	$0	12,500	SEC↗
Shiferman Gregory L.	See Remarks	A Award	2024-11-01	2024-11-01	5,000	—	$0	19,967	SEC↗
Benecchi Christopher	Chief Operating Officer	A Award	2024-11-01	2024-11-14	6,250	—	$0	24,737	SEC↗
Benecchi Christopher	Chief Business Officer	A Award	2024-08-05	2024-08-07	16,200	—	$0	23,242	SEC↗
Benecchi Christopher	Chief Business Officer	F Tax w/h	2024-08-05	2024-08-07	4,755	$8.96	$42.6K	18,487	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award	2024-08-05	2024-08-07	13,500	—	$0	28,543	SEC↗
Cook Anne Marie	SVP, GC & Secretary	F Tax w/h	2024-08-05	2024-08-07	4,503	$8.96	$40.3K	24,040	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award	2024-08-05	2024-08-07	13,500	—	$0	85,041	SEC↗
IGUCHI KIMI	CFO & Treasurer	F Tax w/h	2024-08-05	2024-08-07	3,636	$8.96	$32.6K	81,405	SEC↗
Gault Laura	Chief Medical Officer	A Award	2024-08-05	2024-08-07	13,500	—	$0	14,025	SEC↗
Gault Laura	Chief Medical Officer	F Tax w/h	2024-08-05	2024-08-07	3,288	$8.96	$29.5K	10,737	SEC↗
Greene Barry E	President and CEO	A Award	2024-08-05	2024-08-07	50,400	—	$0	97,340	SEC↗
Greene Barry E	President and CEO	F Tax w/h	2024-08-05	2024-08-07	12,273	$8.96	$110.0K	85,067	SEC↗
Federer Jessica	Director	A Award deriv	2024-06-10	2024-06-11	12,500	—	$0	12,500	SEC↗
Barrett Elizabeth	Director	A Award deriv	2024-06-10	2024-06-11	12,500	—	$0	12,500	SEC↗
COLA MICHAEL F	Director	A Award deriv	2024-06-10	2024-06-11	12,500	—	$0	12,500	SEC↗
FRATES JAMES M	Director	A Award deriv	2024-06-10	2024-06-11	12,500	—	$0	12,500	SEC↗
Germano Geno J	Director	A Award deriv	2024-06-10	2024-06-11	12,500	—	$0	12,500	SEC↗
Golumbeski George	Director	A Award deriv	2024-06-10	2024-06-11	12,500	—	$0	12,500	SEC↗
JONAS JEFFREY M	Director	A Award deriv	2024-06-10	2024-06-11	12,500	—	$0	12,500	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award deriv	2024-02-13	2024-02-15	22,500	—	$0	22,500	SEC↗
Benecchi Christopher	Chief Business Officer	A Award deriv	2024-02-13	2024-02-15	27,000	—	$0	27,000	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award deriv	2024-02-13	2024-02-15	22,500	—	$0	22,500	SEC↗
Greene Barry E	President and CEO	A Award deriv	2024-02-13	2024-02-15	168,000	—	$0	168,000	SEC↗
Gault Laura	Chief Medical Officer	A Award deriv	2024-02-13	2024-02-15	22,500	—	$0	22,500	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award	2024-02-13	2024-02-15	11,250	—	$0	81,679	SEC↗
Benecchi Christopher	Chief Business Officer	A Award	2024-02-13	2024-02-15	13,500	—	$0	19,430	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award	2024-02-13	2024-02-15	11,250	—	$0	25,181	SEC↗
Gault Laura	Chief Medical Officer	A Award	2024-02-13	2024-02-15	11,250	—	$0	11,477	SEC↗
Golumbeski George	Director	A Award deriv	2024-01-03	2024-01-04	3,495	—	$0	3,495	SEC↗
PAUL STEVEN M	Director	A Award deriv	2024-01-03	2024-01-04	3,971	—	$0	3,971	SEC↗
FRATES JAMES M	Director	A Award deriv	2024-01-03	2024-01-04	4,925	—	$0	4,925	SEC↗
Federer Jessica	Director	A Award deriv	2024-01-03	2024-01-04	3,177	—	$0	3,177	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2024-01-02	2024-01-04	1,642	—	$0	0	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2024-01-02	2024-01-04	1,642	$1.36	$2.2K	70,429	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award	2023-11-28	2023-11-30	4,000	—	$0	14,890	SEC↗
Cook Anne Marie	SVP, GC & Secretary	F Tax w/h	2023-11-28	2023-11-30	1,174	$19.27	$22.6K	13,716	SEC↗
IGUCHI KIMI	CFO & Treasurer	F Tax w/h	2023-11-28	2023-11-30	943	$19.27	$18.2K	68,787	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award	2023-11-28	2023-11-30	3,500	—	$0	69,730	SEC↗
JONAS JEFFREY M	Director	A Award	2023-11-28	2023-11-30	10,000	—	$0	131,981	SEC↗
JONAS JEFFREY M	Director	F Tax w/h	2023-11-28	2023-11-30	3,935	$19.27	$75.8K	128,046	SEC↗
Barrett Elizabeth	Director	P Buy	2023-08-09	2023-08-11	2,000	$18.64	$37.3K	3,000	SEC↗
Greene Barry E	President and CEO	A Award deriv	2023-08-04	2023-08-08	195,000	—	$0	195,000	SEC↗
COLA MICHAEL F	Director	A Award deriv	2023-06-15	2023-06-16	10,000	—	$0	10,000	SEC↗
STARR KEVIN P	Director	A Award deriv	2023-06-15	2023-06-16	10,000	—	$0	10,000	SEC↗
Golumbeski George	Director	A Award deriv	2023-06-15	2023-06-16	10,000	—	$0	10,000	SEC↗
PAUL STEVEN M	Director	A Award deriv	2023-06-15	2023-06-16	10,000	—	$0	10,000	SEC↗
Germano Geno J	Director	A Award deriv	2023-06-15	2023-06-16	10,000	—	$0	10,000	SEC↗
JONAS JEFFREY M	Director	A Award deriv	2023-06-15	2023-06-16	10,000	—	$0	10,000	SEC↗
FRATES JAMES M	Director	A Award deriv	2023-06-15	2023-06-16	10,000	—	$0	10,000	SEC↗
Barrett Elizabeth	Director	A Award deriv	2023-06-15	2023-06-16	10,000	—	$0	10,000	SEC↗
Federer Jessica	Director	A Award deriv	2023-06-15	2023-06-16	10,000	—	$0	10,000	SEC↗
Barrett Elizabeth	Director	P Buy	2023-05-09	2023-05-11	1,000	$50.50	$50.5K	1,000	SEC↗
Federer Jessica	Director	A Award deriv	2023-03-16	2023-03-17	19,894	—	$0	19,894	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2023-03-15	2023-03-17	3,000	—	$0	1,642	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2023-03-15	2023-03-17	3,000	$1.36	$4.1K	65,560	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2023-02-23	2023-02-23	250	—	$0	4,642	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2023-02-23	2023-02-23	250	$1.36	$340	62,560	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2023-02-21	2023-02-23	750	—	$0	4,892	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2023-02-21	2023-02-23	750	$1.36	$1.0K	62,310	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award deriv	2023-02-13	2023-02-15	16,720	—	$0	16,720	SEC↗
Greene Barry E	President and CEO	A Award deriv	2023-02-13	2023-02-15	66,500	—	$0	66,500	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award deriv	2023-02-13	2023-02-15	19,000	—	$0	19,000	SEC↗
Benecchi Christopher	Chief Business Officer	A Award deriv	2023-02-13	2023-02-15	20,900	—	$0	20,900	SEC↗
Robichaud Albert	Chief Scientific Officer	A Award deriv	2023-02-13	2023-02-15	16,720	—	$0	16,720	SEC↗
Gault Laura	Chief Medical Officer	A Award deriv	2023-02-13	2023-02-15	2,660	—	$0	2,660	SEC↗
JONAS JEFFREY M	Director	M Exercise deriv	2023-02-10	2023-02-10	11,643	—	$0	0	SEC↗
JONAS JEFFREY M	Director	S Sale	2023-02-10	2023-02-10	3,838	$44.90	$172.3K	121,981	SEC↗
JONAS JEFFREY M	Director	M Exercise	2023-02-10	2023-02-10	11,643	$0.45	$5.2K	133,624	SEC↗
JONAS JEFFREY M	Director	S Sale	2023-02-10	2023-02-10	7,805	$44.47	$347.1K	125,819	SEC↗
Benecchi Christopher	Chief Business Officer	A Award	2023-02-03	2023-02-07	6,750	—	$0	7,379	SEC↗
Benecchi Christopher	Chief Business Officer	F Tax w/h	2023-02-03	2023-02-07	2,119	$44.16	$93.6K	5,260	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award	2023-02-03	2023-02-07	2,850	—	$0	11,478	SEC↗
Cook Anne Marie	SVP, GC & Secretary	F Tax w/h	2023-02-03	2023-02-07	980	$44.16	$43.3K	10,498	SEC↗
IGUCHI KIMI	CFO & Treasurer	F Tax w/h	2023-02-03	2023-02-07	914	$44.16	$40.4K	61,560	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award	2023-02-03	2023-02-07	2,850	—	$0	62,474	SEC↗
Robichaud Albert	Chief Scientific Officer	F Tax w/h	2023-02-03	2023-02-07	1,127	$44.16	$49.8K	145,553	SEC↗
Robichaud Albert	Chief Scientific Officer	A Award	2023-02-03	2023-02-07	3,375	—	$0	146,680	SEC↗
JONAS JEFFREY M	Director	F Tax w/h	2023-02-03	2023-02-07	1,427	$44.16	$63.0K	121,981	SEC↗
JONAS JEFFREY M	Director	A Award	2023-02-03	2023-02-07	5,100	—	$0	123,408	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2023-01-09	2023-01-11	1,600	—	$0	5,642	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2023-01-09	2023-01-11	1,600	$1.36	$2.2K	59,624	SEC↗
Golumbeski George	Director	A Award deriv	2023-01-04	2023-01-05	2,108	—	$0	2,108	SEC↗
PAUL STEVEN M	Director	A Award deriv	2023-01-04	2023-01-05	2,395	—	$0	2,395	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2023-01-04	2023-01-05	1,800	—	$0	7,242	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2023-01-04	2023-01-05	1,800	$1.36	$2.4K	58,024	SEC↗
JONAS JEFFREY M	Director	M Exercise deriv	2023-01-03	2023-01-05	2,501	—	$0	57,499	SEC↗
JONAS JEFFREY M	Director	M Exercise	2023-01-03	2023-01-05	2,501	$28.63	$71.6K	118,308	SEC↗
PAUL STEVEN M	Director	J Other	2022-11-28	2022-11-30	5	$38.17	$191	78,539	SEC↗
Greene Barry E	President and CEO	P Buy	2022-11-10	2022-11-15	14,500	$34.48	$500.0K	46,940	SEC↗
Gault Laura	Chief Medical Officer	A Award deriv	2022-11-01	2022-11-01	64,410	—	$0	64,410	SEC↗
STARR KEVIN P	Director	A Award deriv	2022-06-16	2022-06-17	9,947	—	$0	9,947	SEC↗
PAUL STEVEN M	Director	A Award deriv	2022-06-16	2022-06-17	9,947	—	$0	9,947	SEC↗
Germano Geno J	Director	A Award deriv	2022-06-16	2022-06-17	9,947	—	$0	9,947	SEC↗
Barrett Elizabeth	Director	A Award deriv	2022-06-16	2022-06-17	9,947	—	$0	9,947	SEC↗
Golumbeski George	Director	A Award deriv	2022-06-16	2022-06-17	9,947	—	$0	9,947	SEC↗
COLA MICHAEL F	Director	A Award deriv	2022-06-16	2022-06-17	9,947	—	$0	9,947	SEC↗
FRATES JAMES M	Director	A Award deriv	2022-06-16	2022-06-17	9,947	—	$0	9,947	SEC↗
Benecchi Christopher	Chief Commercial Officer	A Award deriv	2022-06-16	2022-06-21	9,500	—	$0	9,500	SEC↗
Golumbeski George	Director	P Buy	2022-05-05	2022-05-09	8,000	$31.45	$251.6K	8,000	SEC↗
JONAS JEFFREY M	Director	M Exercise deriv	2022-04-27	2022-04-29	30,944	—	$0	11,643	SEC↗
JONAS JEFFREY M	Director	M Exercise	2022-04-27	2022-04-29	30,944	$0.45	$13.9K	115,807	SEC↗
JONAS JEFFREY M	Chief Innovation Officer	M Exercise deriv	2022-02-17	2022-02-18	4,000	—	$0	42,587	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2022-02-17	2022-02-18	4,500	—	$0	9,042	SEC↗
JONAS JEFFREY M	Chief Innovation Officer	M Exercise	2022-02-17	2022-02-18	4,000	$0.45	$1.8K	84,863	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2022-02-17	2022-02-18	4,500	$1.36	$6.1K	55,600	SEC↗
JONAS JEFFREY M	Chief Innovation Officer	A Award deriv	2022-02-11	2022-02-15	15,200	—	$0	15,200	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award deriv	2022-02-11	2022-02-15	15,200	—	$0	15,200	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award deriv	2022-02-11	2022-02-15	15,200	—	$0	15,200	SEC↗
Robichaud Albert	Chief Scientific Officer	A Award deriv	2022-02-11	2022-02-15	13,300	—	$0	13,300	SEC↗
Greene Barry E	President and CEO	A Award deriv	2022-02-11	2022-02-15	69,920	—	$0	69,920	SEC↗
Benecchi Christopher	Chief Commercial Officer	A Award deriv	2022-02-11	2022-02-15	11,400	—	$0	11,400	SEC↗
Golumbeski George	Director	A Award deriv	2022-01-04	2022-01-05	1,638	—	$0	1,638	SEC↗
Barrett Elizabeth	Director	A Award deriv	2022-01-04	2022-01-05	2,048	—	$0	2,048	SEC↗
PAUL STEVEN M	Director	A Award deriv	2022-01-04	2022-01-05	1,638	—	$0	1,638	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2021-11-23	2021-11-23	505	—	$0	13,542	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2021-11-23	2021-11-23	495	—	$0	0	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2021-11-23	2021-11-23	1,000	$1.36	$1.4K	51,100	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2021-11-22	2021-11-23	2,500	—	$0	495	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2021-11-22	2021-11-23	2,500	$1.36	$3.4K	50,100	SEC↗
PAUL STEVEN M	Director	J Other	2021-11-09	2021-11-12	1	$43.36	$43	1	SEC↗
Kanes Stephen	Chief Medical Officer	F Tax w/h	2021-10-19	2021-10-21	1,120	$40.29	$45.1K	13,471	SEC↗
Kanes Stephen	Chief Medical Officer	A Award	2021-10-19	2021-10-21	3,800	—	$0	14,591	SEC↗
JONAS JEFFREY M	Chief Innovation Officer	F Tax w/h	2021-10-19	2021-10-21	4,374	$40.29	$176.2K	80,863	SEC↗
JONAS JEFFREY M	Chief Innovation Officer	A Award	2021-10-19	2021-10-21	10,000	—	$0	85,237	SEC↗
Cook Anne Marie	SVP, GC & Secretary	F Tax w/h	2021-10-19	2021-10-21	1,116	$40.29	$45.0K	7,894	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award	2021-10-19	2021-10-21	3,800	—	$0	9,010	SEC↗
Robichaud Albert	Chief Scientific Officer	F Tax w/h	2021-10-19	2021-10-21	1,116	$40.29	$45.0K	142,619	SEC↗
Robichaud Albert	Chief Scientific Officer	A Award	2021-10-19	2021-10-21	3,800	—	$0	143,735	SEC↗
IGUCHI KIMI	CFO & Treasurer	F Tax w/h	2021-10-19	2021-10-21	1,024	$40.29	$41.3K	47,600	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award	2021-10-19	2021-10-21	3,800	—	$0	48,624	SEC↗
Benecchi Christopher	Chief Commercial Officer	A Award deriv	2021-10-01	2021-10-04	45,000	—	$0	45,000	SEC↗
Greene Barry E	President and CEO	P Buy	2021-08-05	2021-08-09	23,640	$43.15	$1.02M	32,440	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2021-06-16	2021-06-17	2,000	—	$0	14,047	SEC↗
JONAS JEFFREY M	Chief Innovation Officer	M Exercise deriv	2021-06-16	2021-06-17	12,000	—	$0	46,587	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2021-06-16	2021-06-17	2,000	$1.36	$2.7K	44,533	SEC↗
JONAS JEFFREY M	Chief Innovation Officer	M Exercise	2021-06-16	2021-06-17	12,000	$0.45	$5.4K	75,237	SEC↗
Greene Barry E	President and CEO	P Buy	2021-06-16	2021-06-17	8,800	$56.32	$495.6K	8,800	SEC↗
STARR KEVIN P	Director	P Buy	2021-06-16	2021-06-17	17,842	$56.05	$1.00M	320,659	SEC↗
FRATES JAMES M	Director	P Buy	2021-06-16	2021-06-17	1,810	$55.10	$99.7K	1,810	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2021-06-15	2021-06-17	3,000	—	$0	16,047	SEC↗
IGUCHI KIMI	CFO & Treasurer	F Tax w/h	2021-06-15	2021-06-17	822	$58.80	$48.3K	42,533	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award	2021-06-15	2021-06-17	3,500	—	$0	43,355	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2021-06-15	2021-06-17	3,000	$1.36	$4.1K	39,855	SEC↗
Kanes Stephen	Chief Medical Officer	F Tax w/h	2021-06-15	2021-06-17	1,001	$58.80	$58.9K	10,791	SEC↗
Kanes Stephen	Chief Medical Officer	A Award	2021-06-15	2021-06-17	3,500	—	$0	11,792	SEC↗
Robichaud Albert	Chief Scientific Officer	F Tax w/h	2021-06-15	2021-06-17	1,144	$58.80	$67.3K	139,651	SEC↗
Robichaud Albert	Chief Scientific Officer	A Award	2021-06-15	2021-06-17	4,000	—	$0	140,795	SEC↗
JONAS JEFFREY M	Chief Innovation Officer	A Award	2021-06-15	2021-06-17	10,000	—	$0	66,330	SEC↗
JONAS JEFFREY M	Chief Innovation Officer	F Tax w/h	2021-06-15	2021-06-17	3,093	$58.80	$181.9K	63,237	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award	2021-06-15	2021-06-17	4,000	—	$0	6,117	SEC↗
Cook Anne Marie	SVP, GC & Secretary	F Tax w/h	2021-06-15	2021-06-17	1,144	$58.80	$67.3K	4,973	SEC↗
STARR KEVIN P	Director	A Award deriv	2021-06-10	2021-06-11	10,000	—	$0	10,000	SEC↗
PAUL STEVEN M	Director	A Award deriv	2021-06-10	2021-06-11	10,000	—	$0	10,000	SEC↗
Germano Geno J	Director	A Award deriv	2021-06-10	2021-06-11	10,000	—	$0	10,000	SEC↗
Barrett Elizabeth	Director	A Award deriv	2021-06-10	2021-06-11	10,000	—	$0	10,000	SEC↗
COLA MICHAEL F	Director	A Award deriv	2021-06-10	2021-06-11	10,000	—	$0	10,000	SEC↗
Golumbeski George	Director	A Award deriv	2021-06-10	2021-06-11	10,000	—	$0	10,000	SEC↗
FRATES JAMES M	Director	A Award deriv	2021-06-10	2021-06-11	10,000	—	$0	10,000	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2021-04-13	2021-04-14	552	—	$0	2,995	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2021-04-13	2021-04-14	948	—	$0	0	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2021-04-13	2021-04-14	1,500	$1.36	$2.0K	36,855	SEC↗
Cloonan Michael	Chief Business Officer	A Award deriv	2021-02-10	2021-02-12	19,000	—	$0	19,000	SEC↗
Kanes Stephen	Chief Medical Officer	A Award deriv	2021-02-10	2021-02-12	19,000	—	$0	19,000	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award deriv	2021-02-10	2021-02-12	19,000	—	$0	19,000	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award deriv	2021-02-10	2021-02-12	19,000	—	$0	19,000	SEC↗
Robichaud Albert	Chief Scientific Officer	A Award deriv	2021-02-10	2021-02-12	22,500	—	$0	22,500	SEC↗
JONAS JEFFREY M	Chief Innovation Officer	A Award deriv	2021-02-10	2021-02-12	34,000	—	$0	34,000	SEC↗
JONAS JEFFREY M	Chief Innovation Officer	M Exercise deriv	2021-01-27	2021-01-28	1,800	—	$0	58,587	SEC↗
JONAS JEFFREY M	Chief Innovation Officer	M Exercise	2021-01-27	2021-01-28	1,800	$0.45	$810	56,330	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2021-01-05	2021-01-06	1,750	—	$0	948	SEC↗
Golumbeski George	Director	A Award deriv	2021-01-05	2021-01-06	832	—	$0	832	SEC↗
Barrett Elizabeth	Director	A Award deriv	2021-01-05	2021-01-06	915	—	$0	915	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2021-01-05	2021-01-06	1,750	$1.36	$2.4K	35,355	SEC↗
Greene Barry E	President and CEO	A Award deriv	2021-01-04	2021-01-06	390,000	—	$0	390,000	SEC↗
Greene Barry E	Director	A Award deriv	2020-10-01	2020-10-05	20,000	—	$0	20,000	SEC↗
Barrett Elizabeth	Director	A Award deriv	2020-06-09	2020-06-11	10,000	—	$0	10,000	SEC↗
COLA MICHAEL F	Director	A Award deriv	2020-06-09	2020-06-11	10,000	—	$0	10,000	SEC↗
FRATES JAMES M	Director	A Award deriv	2020-06-09	2020-06-11	10,000	—	$0	10,000	SEC↗
Germano Geno J	Director	A Award deriv	2020-06-09	2020-06-11	10,000	—	$0	10,000	SEC↗
Golumbeski George	Director	A Award deriv	2020-06-09	2020-06-11	10,000	—	$0	10,000	SEC↗
PAUL STEVEN M	Director	A Award deriv	2020-06-09	2020-06-11	10,000	—	$0	10,000	SEC↗
STARR KEVIN P	Director	A Award deriv	2020-06-09	2020-06-11	10,000	—	$0	10,000	SEC↗
Cloonan Michael	Chief Business Officer	A Award deriv	2020-05-01	2020-05-05	50,000	—	$0	50,000	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2020-04-30	2020-05-04	4,000	—	$0	2,698	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2020-04-30	2020-05-04	4,000	$1.36	$5.4K	33,261	SEC↗
Robichaud Albert	Chief Scientific Officer	A Award deriv	2020-04-28	2020-04-30	9,450	—	$0	9,450	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award deriv	2020-04-28	2020-04-30	9,450	—	$0	9,450	SEC↗
Kanes Stephen	Chief Medical Officer	A Award deriv	2020-04-28	2020-04-30	9,450	—	$0	9,450	SEC↗
Cloonan Michael	Chief Business Officer	A Award deriv	2020-04-28	2020-04-30	9,450	—	$0	9,450	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award deriv	2020-04-28	2020-04-30	9,450	—	$0	9,450	SEC↗
JONAS JEFFREY M	President & CEO	A Award deriv	2020-04-28	2020-04-30	15,385	—	$0	15,385	SEC↗
JONAS JEFFREY M	President & CEO	A Award deriv	2020-02-12	2020-02-14	50,000	—	$0	50,000	SEC↗
Cloonan Michael	Chief Business Officer	A Award deriv	2020-02-12	2020-02-14	22,500	—	$0	22,500	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award deriv	2020-02-12	2020-02-14	20,000	—	$0	20,000	SEC↗
Robichaud Albert	Chief Scientific Officer	A Award deriv	2020-02-12	2020-02-14	20,000	—	$0	20,000	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award deriv	2020-02-12	2020-02-14	17,500	—	$0	17,500	SEC↗
Kanes Stephen	Chief Medical Officer	A Award deriv	2020-02-12	2020-02-14	17,500	—	$0	17,500	SEC↗
Golumbeski George	Director	A Award deriv	2020-01-03	2020-01-07	976	—	$0	976	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2019-12-10	2019-12-10	500	—	$0	3,547	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2019-12-10	2019-12-10	500	$1.36	$680	29,261	SEC↗
Robichaud Albert	Chief Scientific Officer	M Exercise deriv	2019-12-09	2019-12-10	5,732	—	$0	32,668	SEC↗
Robichaud Albert	Chief Scientific Officer	M Exercise deriv	2019-12-09	2019-12-10	6,935	—	$0	0	SEC↗
Robichaud Albert	Chief Scientific Officer	M Exercise deriv	2019-12-09	2019-12-10	3,076	—	$0	21,924	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2019-12-09	2019-12-10	15,000	—	$0	4,047	SEC↗
JONAS JEFFREY M	President & CEO	P Buy	2019-12-09	2019-12-10	7,500	$64.20	$481.5K	54,530	SEC↗
Robichaud Albert	Chief Scientific Officer	M Exercise	2019-12-09	2019-12-10	6,935	$1.36	$9.4K	102,592	SEC↗
Robichaud Albert	Chief Scientific Officer	P Buy	2019-12-09	2019-12-10	25,000	$64.16	$1.60M	136,400	SEC↗
Robichaud Albert	Chief Scientific Officer	M Exercise	2019-12-09	2019-12-10	3,076	$28.63	$88.1K	111,400	SEC↗
Robichaud Albert	Chief Scientific Officer	M Exercise	2019-12-09	2019-12-10	5,732	$38.25	$219.2K	108,324	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2019-12-09	2019-12-10	15,000	$1.36	$20.4K	28,761	SEC↗
JONAS JEFFREY M	President & CEO	M Exercise deriv	2019-09-11	2019-09-12	4,600	—	$0	60,387	SEC↗
JONAS JEFFREY M	President & CEO	M Exercise	2019-09-11	2019-09-12	4,600	$0.45	$2.1K	47,030	SEC↗
Kanes Stephen	Chief Medical Officer	M Exercise deriv	2019-09-04	2019-09-05	6,000	—	$0	86,100	SEC↗
Kanes Stephen	Chief Medical Officer	M Exercise	2019-09-04	2019-09-05	6,000	$0.45	$2.7K	8,292	SEC↗
FRATES JAMES M	Director	M Exercise deriv	2019-08-15	2019-08-16	8,000	—	$0	5,922	SEC↗
FRATES JAMES M	Director	S Sale	2019-08-15	2019-08-16	8,000	$160.58	$1.28M	2,535	SEC↗
FRATES JAMES M	Director	M Exercise	2019-08-15	2019-08-16	8,000	$28.35	$226.8K	10,535	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2019-07-25	2019-07-25	2,000	—	$0	6,698	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2019-07-25	2019-07-25	2,000	$1.36	$2.7K	12,409	SEC↗
Cook Anne Marie	SVP, GC & Secretary	F Tax w/h	2019-07-25	2019-07-29	844	$161.38	$136.2K	1,756	SEC↗
Cook Anne Marie	SVP, GC & Secretary	A Award	2019-07-25	2019-07-29	1,900	—	$0	2,600	SEC↗
IGUCHI KIMI	CFO & Treasurer	F Tax w/h	2019-07-25	2019-07-29	548	$161.38	$88.4K	13,761	SEC↗
IGUCHI KIMI	CFO & Treasurer	A Award	2019-07-25	2019-07-29	1,900	—	$0	14,309	SEC↗
Kanes Stephen	Chief Medical Officer	A Award	2019-07-25	2019-07-29	1,900	—	$0	2,841	SEC↗
Kanes Stephen	Chief Medical Officer	F Tax w/h	2019-07-25	2019-07-29	549	$161.38	$88.6K	2,292	SEC↗
Robichaud Albert	Chief Scientific Officer	F Tax w/h	2019-07-25	2019-07-29	548	$161.38	$88.4K	95,657	SEC↗
Robichaud Albert	Chief Scientific Officer	A Award	2019-07-25	2019-07-29	1,900	—	$0	96,205	SEC↗
JONAS JEFFREY M	President & CEO	A Award	2019-07-25	2019-07-29	5,000	—	$0	44,115	SEC↗
JONAS JEFFREY M	President & CEO	F Tax w/h	2019-07-25	2019-07-29	1,685	$161.38	$271.9K	42,430	SEC↗
Cloonan Michael	Chief Business Officer	F Tax w/h	2019-07-25	2019-07-29	1,088	$161.38	$175.6K	2,102	SEC↗
Cloonan Michael	Chief Business Officer	A Award	2019-07-25	2019-07-29	2,450	—	$0	3,190	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise deriv	2019-07-17	2019-07-17	4,000	—	$0	8,698	SEC↗
IGUCHI KIMI	CFO & Treasurer	M Exercise	2019-07-17	2019-07-17	4,000	$1.36	$5.4K	10,409	SEC↗
JONAS JEFFREY M	President & CEO	M Exercise deriv	2019-07-16	2019-07-17	27,000	—	$0	64,987	SEC↗
JONAS JEFFREY M	President & CEO	M Exercise	2019-07-16	2019-07-17	27,000	$0.45	$12.2K	39,115	SEC↗