Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$0
Insiders on file
22
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Melincoff Gwen A | Director | 6 | $0 | $0 | 2016-11-01 |
| Lefebvre Eric | Chief Medical Officer | 7 | $0 | $0 | 2016-11-01 |
| Peetz Christopher | Chief Financial Officer | 8 | $0 | $0 | 2016-11-01 |
| Jenkins Helen | Chief Operating Officer | 9 | $0 | $0 | 2016-11-01 |
| Brosgart Carol L | Director | 11 | $0 | $0 | 2016-11-01 |
| Legault Pierre | Director | 7 | $0 | $0 | 2016-11-01 |
| Fischer Laurent | Chief Executive Officer | 17 | $0 | $0 | 2016-11-01 |
| DP VII ASSOCIATES LP | 10% Owner | 1 | $0 | $0 | 2016-11-01 |
| Heron Patrick J | Director | 7 | $0 | $0 | 2016-11-01 |
| Fromkin Andrew J. | Director | 8 | $0 | $0 | 2016-11-01 |
| Frazier Healthcare V, LP | 10% Owner | 2 | $0 | $0 | 2016-11-01 |
| Podlesak Dennis | Director | 12 | $0 | $0 | 2016-11-01 |
| Cooper Jeffrey H | Director | 6 | $0 | $0 | 2016-11-01 |
| DP VI Associates, L.P. | 10% Owner | 1 | $0 | $0 | 2016-11-01 |
| WEBER ECKARD | Director | 13 | $0 | $0 | 2016-11-01 |
| DOVEY BRIAN H | 10% Owner | 1 | $0 | $0 | 2016-11-01 |
| VITULLO NICOLE | 10% Owner | 1 | $0 | $0 | 2016-11-01 |
| BLAIR JAMES C | 10% Owner | 4 | $0 | $0 | 2016-11-01 |
| Pentwater Capital Management LP | 10% Owner | 23 | $72.30M | $0 | 2016-10-31 |
| Novo A/S | 10% Owner | 17 | $8.90M | $8.15M | 2016-07-13 |
| SCHOEMAKER KATHLEEN K | 10% Owner | 1 | $2.95M | $0 | 2015-05-04 |
| DOMAIN ASSOCIATES | 10% Owner | 1 | $0 | $0 | 2015-05-04 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Fischer Laurent | Chief Executive Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 16,416 | — | $0 | 0 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 105,000 | — | $0 | 0 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 503,882 | — | $0 | 0 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 83,324 | — | $0 | 0 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 258,000 | — | $0 | 0 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 53,616 | — | $0 | 0 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 4,332 | — | $0 | 0 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 4,332 | — | $0 | 0 | SEC↗ |
| Lefebvre Eric | Chief Medical Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 100,000 | — | $0 | 0 | SEC↗ |
| Lefebvre Eric | Chief Medical Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 101,000 | — | $0 | 0 | SEC↗ |
| Lefebvre Eric | Chief Medical Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 79,287 | — | $0 | 0 | SEC↗ |
| Peetz Christopher | Chief Financial Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 31,091 | — | $0 | 0 | SEC↗ |
| Peetz Christopher | Chief Financial Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 85,000 | — | $0 | 0 | SEC↗ |
| Peetz Christopher | Chief Financial Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 101,000 | — | $0 | 0 | SEC↗ |
| Peetz Christopher | Chief Financial Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 68,732 | — | $0 | 0 | SEC↗ |
| Jenkins Helen | Chief Operating Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 29,841 | — | $0 | 0 | SEC↗ |
| Jenkins Helen | Chief Operating Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 65,000 | — | $0 | 0 | SEC↗ |
| Jenkins Helen | Chief Operating Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 101,000 | — | $0 | 0 | SEC↗ |
| Jenkins Helen | Chief Operating Officer | D To issuer deriv | 2016-11-01 | 2016-11-03 | 29,548 | — | $0 | 0 | SEC↗ |
| Podlesak Dennis | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 40,733 | — | $0 | 0 | SEC↗ |
| Podlesak Dennis | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 2,947 | — | $0 | 0 | SEC↗ |
| Podlesak Dennis | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 53,334 | — | $0 | 0 | SEC↗ |
| Podlesak Dennis | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 27,500 | — | $0 | 0 | SEC↗ |
| Podlesak Dennis | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 1,071 | — | $0 | 0 | SEC↗ |
| Podlesak Dennis | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 17,695 | — | $0 | 0 | SEC↗ |
| Podlesak Dennis | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 10,253 | — | $0 | 0 | SEC↗ |
| Podlesak Dennis | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 232 | — | $0 | 0 | SEC↗ |
| Podlesak Dennis | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 9,314 | — | $0 | 0 | SEC↗ |
| Podlesak Dennis | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 232 | — | $0 | 0 | SEC↗ |
| Fromkin Andrew J. | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 15,500 | — | $0 | 0 | SEC↗ |
| Fromkin Andrew J. | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 17,778 | — | $0 | 0 | SEC↗ |
| Fromkin Andrew J. | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 17,695 | — | $0 | 0 | SEC↗ |
| Fromkin Andrew J. | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 5,666 | — | $0 | 0 | SEC↗ |
| Legault Pierre | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 15,500 | — | $0 | 0 | SEC↗ |
| Legault Pierre | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 6,111 | — | $0 | 0 | SEC↗ |
| Legault Pierre | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 17,695 | — | $0 | 0 | SEC↗ |
| Legault Pierre | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 17,778 | — | $0 | 0 | SEC↗ |
| Legault Pierre | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 535 | — | $0 | 0 | SEC↗ |
| Heron Patrick J | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 15,500 | — | $0 | 0 | SEC↗ |
| Heron Patrick J | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 4,332 | — | $0 | 0 | SEC↗ |
| Heron Patrick J | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 17,778 | — | $0 | 0 | SEC↗ |
| WEBER ECKARD | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 17,778 | — | $0 | 0 | SEC↗ |
| WEBER ECKARD | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 4,332 | — | $0 | 0 | SEC↗ |
| WEBER ECKARD | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 15,500 | — | $0 | 0 | SEC↗ |
| Cooper Jeffrey H | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 13,539 | — | $0 | 0 | SEC↗ |
| Cooper Jeffrey H | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 17,778 | — | $0 | 0 | SEC↗ |
| Cooper Jeffrey H | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 15,500 | — | $0 | 0 | SEC↗ |
| Melincoff Gwen A | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 15,500 | — | $0 | 0 | SEC↗ |
| Melincoff Gwen A | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 13,539 | — | $0 | 0 | SEC↗ |
| Melincoff Gwen A | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 17,778 | — | $0 | 0 | SEC↗ |
| Brosgart Carol L | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 4,332 | — | $0 | 0 | SEC↗ |
| Brosgart Carol L | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 4,332 | — | $0 | 0 | SEC↗ |
| Brosgart Carol L | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 18,956 | — | $0 | 0 | SEC↗ |
| Brosgart Carol L | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 15,500 | — | $0 | 0 | SEC↗ |
| Brosgart Carol L | Director | D To issuer deriv | 2016-11-01 | 2016-11-03 | 17,778 | — | $0 | 0 | SEC↗ |
| BLAIR JAMES C | 10% Owner | D To issuer deriv | 2016-11-01 | 2016-11-04 | 1,071 | — | $0 | 0 | SEC↗ |
| BLAIR JAMES C | 10% Owner | D To issuer deriv | 2016-11-01 | 2016-11-04 | 17,695 | — | $0 | 0 | SEC↗ |
| BLAIR JAMES C | 10% Owner | D To issuer deriv | 2016-11-01 | 2016-11-04 | 1,996 | — | $0 | 0 | SEC↗ |
| Fromkin Andrew J. | Director | U Tender | 2016-11-01 | 2016-11-03 | 11 | — | $0 | 0 | SEC↗ |
| Fromkin Andrew J. | Director | U Tender | 2016-11-01 | 2016-11-03 | 5 | — | $0 | 0 | SEC↗ |
| WEBER ECKARD | Director | U Tender | 2016-11-01 | 2016-11-03 | 243,726 | — | $0 | 0 | SEC↗ |
| Frazier Healthcare V, LP | 10% Owner | U Tender | 2016-11-01 | 2016-11-03 | 2,668,570 | $28.35 | $75.65M | 0 | SEC↗ |
| VITULLO NICOLE | 10% Owner | U Tender | 2016-11-01 | 2016-11-03 | 285,679 | $28.35 | $8.10M | 0 | SEC↗ |
| DP VII ASSOCIATES LP | 10% Owner | U Tender | 2016-11-01 | 2016-11-03 | 47,613 | $28.35 | $1.35M | 0 | SEC↗ |
| DOVEY BRIAN H | 10% Owner | U Tender | 2016-11-01 | 2016-11-03 | 3,553,322 | $28.35 | $100.74M | 0 | SEC↗ |
| DP VI Associates, L.P. | 10% Owner | U Tender | 2016-11-01 | 2016-11-03 | 1,657 | $28.35 | $47.0K | 0 | SEC↗ |
| BLAIR JAMES C | 10% Owner | U Tender | 2016-11-01 | 2016-11-04 | 38,094 | $28.35 | $1.08M | 0 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-10-31 | 2016-11-02 | 10,000 | $41.71 | $417.1K | 3,753,200 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-10-31 | 2016-11-02 | 5,000 | $42.10 | $210.5K | 3,758,200 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-10-18 | 2016-10-19 | 8,300 | $40.04 | $332.3K | 3,743,200 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-10-17 | 2016-10-19 | 27,400 | $40.10 | $1.10M | 3,734,900 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-10-17 | 2016-10-19 | 4,300 | $39.89 | $171.5K | 3,707,500 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-10-04 | 2016-10-06 | 4,481 | $39.83 | $178.5K | 3,703,200 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-29 | 2016-09-30 | 9,019 | $39.49 | $356.2K | 3,698,719 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-29 | 2016-09-30 | 6,500 | $39.49 | $256.7K | 3,689,700 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-26 | 2016-09-28 | 49,400 | $39.00 | $1.93M | 3,683,200 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-26 | 2016-09-28 | 600 | $39.01 | $23.4K | 3,633,800 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-23 | 2016-09-23 | 95,000 | $39.19 | $3.72M | 3,628,200 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-23 | 2016-09-23 | 5,000 | $39.09 | $195.5K | 3,633,200 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-22 | 2016-09-22 | 1,209 | $39.26 | $47.5K | 3,435,409 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-22 | 2016-09-22 | 50,000 | $39.30 | $1.96M | 3,485,409 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-22 | 2016-09-22 | 27,791 | $39.40 | $1.09M | 3,513,200 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-22 | 2016-09-22 | 20,000 | $39.45 | $789.0K | 3,533,200 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-21 | 2016-09-22 | 3,200 | $39.12 | $125.2K | 3,208,200 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-21 | 2016-09-22 | 31,000 | $38.97 | $1.21M | 3,239,200 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-21 | 2016-09-22 | 195,000 | $39.14 | $7.63M | 3,434,200 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-20 | 2016-09-22 | 1,070,000 | $39.03 | $41.76M | 2,979,000 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-20 | 2016-09-22 | 1,000 | $39.23 | $39.2K | 2,980,000 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-20 | 2016-09-22 | 5,000 | $39.07 | $195.3K | 3,205,000 | SEC↗ |
| Pentwater Capital Management L | 10% Owner | P Buy | 2016-09-20 | 2016-09-22 | 220,000 | $38.87 | $8.55M | 3,200,000 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-07-13 | 2016-07-13 | 29,884 | $11.88 | $355.0K | 1,875,905 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-07-12 | 2016-07-13 | 8,752 | $12.12 | $106.1K | 1,905,789 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-07-11 | 2016-07-13 | 20,431 | $12.19 | $249.1K | 1,914,541 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-07-07 | 2016-07-07 | 21,869 | $12.03 | $263.1K | 1,934,972 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-07-06 | 2016-07-07 | 59,850 | $12.20 | $730.2K | 1,956,841 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-07-05 | 2016-07-07 | 10,400 | $12.57 | $130.7K | 2,016,691 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-06-30 | 2016-06-30 | 27,133 | $12.58 | $341.3K | 2,027,091 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-06-29 | 2016-06-30 | 16,068 | $12.63 | $202.9K | 2,054,224 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-06-28 | 2016-06-30 | 20,883 | $13.77 | $287.6K | 2,073,022 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-06-28 | 2016-06-30 | 2,730 | $14.28 | $39.0K | 2,070,292 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-06-06 | 2016-06-07 | 187,500 | $10.37 | $1.94M | 2,093,905 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-03-04 | 2016-03-04 | 55,000 | $6.54 | $359.7K | 2,281,405 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-03-03 | 2016-03-04 | 25,000 | $6.86 | $171.5K | 2,336,405 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2016-03-02 | 2016-03-04 | 110,000 | $6.92 | $761.2K | 2,361,405 | SEC↗ |
| Podlesak Dennis | Director | A Award deriv | 2016-01-12 | 2016-01-14 | 53,334 | — | $0 | 53,334 | SEC↗ |
| Legault Pierre | Director | A Award deriv | 2016-01-12 | 2016-01-14 | 17,778 | — | $0 | 17,778 | SEC↗ |
| Fromkin Andrew J. | Director | A Award deriv | 2016-01-12 | 2016-01-14 | 17,778 | — | $0 | 17,778 | SEC↗ |
| WEBER ECKARD | Director | A Award deriv | 2016-01-12 | 2016-01-14 | 17,778 | — | $0 | 17,778 | SEC↗ |
| Heron Patrick J | Director | A Award deriv | 2016-01-12 | 2016-01-14 | 17,778 | — | $0 | 17,778 | SEC↗ |
| Brosgart Carol L | Director | A Award deriv | 2016-01-12 | 2016-01-14 | 17,778 | — | $0 | 17,778 | SEC↗ |
| Cooper Jeffrey H | Director | A Award deriv | 2016-01-12 | 2016-01-14 | 17,778 | — | $0 | 17,778 | SEC↗ |
| Melincoff Gwen A | Director | A Award deriv | 2016-01-12 | 2016-01-14 | 17,778 | — | $0 | 17,778 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | A Award deriv | 2016-01-12 | 2016-01-14 | 258,000 | — | $0 | 258,000 | SEC↗ |
| Lefebvre Eric | Chief Medical Officer | A Award deriv | 2016-01-12 | 2016-01-14 | 101,000 | — | $0 | 101,000 | SEC↗ |
| Peetz Christopher | Chief Financial Officer | A Award deriv | 2016-01-12 | 2016-01-14 | 101,000 | — | $0 | 101,000 | SEC↗ |
| Jenkins Helen | Chief Operating Officer | A Award deriv | 2016-01-12 | 2016-01-14 | 101,000 | — | $0 | 101,000 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2015-11-18 | 2015-11-19 | 153,601 | $9.76 | $1.50M | 2,471,405 | SEC↗ |
| Novo A/S | 10% Owner | S Sale | 2015-11-17 | 2015-11-19 | 71,399 | $9.87 | $704.7K | 2,625,006 | SEC↗ |
| WEBER ECKARD | Director | A Award deriv | 2015-07-09 | 2015-07-13 | 15,500 | — | $0 | 15,500 | SEC↗ |
| Heron Patrick J | Director | A Award deriv | 2015-07-09 | 2015-07-13 | 15,500 | — | $0 | 15,500 | SEC↗ |
| Brosgart Carol L | Director | A Award deriv | 2015-07-09 | 2015-07-13 | 15,500 | — | $0 | 15,500 | SEC↗ |
| Cooper Jeffrey H | Director | A Award deriv | 2015-07-09 | 2015-07-13 | 15,500 | — | $0 | 15,500 | SEC↗ |
| Melincoff Gwen A | Director | A Award deriv | 2015-07-09 | 2015-07-13 | 15,500 | — | $0 | 15,500 | SEC↗ |
| Legault Pierre | Director | A Award deriv | 2015-07-09 | 2015-07-13 | 15,500 | — | $0 | 15,500 | SEC↗ |
| Fromkin Andrew J. | Director | A Award deriv | 2015-07-09 | 2015-07-13 | 15,500 | — | $0 | 15,500 | SEC↗ |
| Podlesak Dennis | Director | A Award deriv | 2015-07-09 | 2015-07-13 | 27,500 | — | $0 | 27,500 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | A Award deriv | 2015-05-15 | 2015-05-18 | 105,000 | — | $0 | 105,000 | SEC↗ |
| Lefebvre Eric | Chief Medical Officer | A Award deriv | 2015-05-15 | 2015-05-18 | 100,000 | — | $0 | 100,000 | SEC↗ |
| Peetz Christopher | Chief Financial Officer | A Award deriv | 2015-05-15 | 2015-05-18 | 85,000 | — | $0 | 85,000 | SEC↗ |
| Jenkins Helen | Chief Operating Officer | A Award deriv | 2015-05-15 | 2015-05-18 | 65,000 | — | $0 | 65,000 | SEC↗ |
| Peetz Christopher | Chief Financial Officer | A Award deriv | 2015-05-06 | 2015-05-06 | 68,732 | — | $0 | 68,732 | SEC↗ |
| Peetz Christopher | Chief Financial Officer | A Award deriv | 2015-05-06 | 2015-05-06 | 31,091 | — | $0 | 99,823 | SEC↗ |
| Brosgart Carol L | Director | A Award deriv | 2015-05-04 | 2015-05-06 | 4,332 | — | $0 | 12,996 | SEC↗ |
| Brosgart Carol L | Director | A Award deriv | 2015-05-04 | 2015-05-06 | 4,332 | — | $0 | 8,664 | SEC↗ |
| Brosgart Carol L | Director | A Award deriv | 2015-05-04 | 2015-05-06 | 4,332 | — | $0 | 4,332 | SEC↗ |
| Brosgart Carol L | Director | A Award deriv | 2015-05-04 | 2015-05-06 | 18,956 | — | $0 | 31,952 | SEC↗ |
| Heron Patrick J | Director | A Award deriv | 2015-05-04 | 2015-05-06 | 4,332 | — | $0 | 4,332 | SEC↗ |
| Cooper Jeffrey H | Director | A Award deriv | 2015-05-04 | 2015-05-06 | 13,539 | — | $0 | 13,539 | SEC↗ |
| Jenkins Helen | Chief Operating Officer | A Award deriv | 2015-05-04 | 2015-05-06 | 29,548 | — | $0 | 29,548 | SEC↗ |
| Jenkins Helen | Chief Operating Officer | A Award deriv | 2015-05-04 | 2015-05-06 | 16,311 | — | $0 | 45,859 | SEC↗ |
| Jenkins Helen | Chief Operating Officer | A Award deriv | 2015-05-04 | 2015-05-06 | 29,841 | — | $0 | 75,700 | SEC↗ |
| Lefebvre Eric | Chief Medical Officer | A Award deriv | 2015-05-04 | 2015-05-06 | 79,287 | — | $0 | 79,287 | SEC↗ |
| Lefebvre Eric | Chief Medical Officer | A Award deriv | 2015-05-04 | 2015-05-06 | 21,607 | — | $0 | 100,894 | SEC↗ |
| Melincoff Gwen A | Director | A Award deriv | 2015-05-04 | 2015-05-06 | 13,539 | — | $0 | 13,539 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | A Award deriv | 2015-05-04 | 2015-05-06 | 83,324 | — | $0 | 168,789 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | A Award deriv | 2015-05-04 | 2015-05-06 | 4,332 | — | $0 | 4,332 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | A Award deriv | 2015-05-04 | 2015-05-06 | 4,332 | — | $0 | 8,664 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | A Award deriv | 2015-05-04 | 2015-05-06 | 53,616 | — | $0 | 62,280 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | A Award deriv | 2015-05-04 | 2015-05-06 | 503,882 | — | $0 | 672,671 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | A Award deriv | 2015-05-04 | 2015-05-06 | 6,769 | — | $0 | 85,465 | SEC↗ |
| Fischer Laurent | Chief Executive Officer | A Award deriv | 2015-05-04 | 2015-05-06 | 16,416 | — | $0 | 78,696 | SEC↗ |
| WEBER ECKARD | Director | A Award deriv | 2015-05-04 | 2015-05-07 | 4,332 | — | $0 | 4,332 | SEC↗ |
| WEBER ECKARD | Director | A Award deriv | 2015-05-04 | 2015-05-07 | 4,332 | — | $0 | 4,332 | SEC↗ |
| SCHOEMAKER KATHLEEN K | 10% Owner | P Buy | 2015-05-04 | 2015-05-06 | 277,777 | $10.62 | $2.95M | 3,553,322 | SEC↗ |
| DOMAIN ASSOCIATES | 10% Owner | J Other | 2015-05-04 | 2015-05-06 | 36,187 | — | $0 | 38,094 | SEC↗ |
| Novo A/S | 10% Owner | P Buy | 2015-05-04 | 2015-05-06 | 838,041 | $10.62 | $8.90M | 2,696,405 | SEC↗ |
| Heron Patrick J | Director | A Award | 2015-05-04 | 2015-05-06 | 2,668,570 | — | $0 | 2,668,570 | SEC↗ |
| Frazier Healthcare V, LP | 10% Owner | A Award | 2015-05-04 | 2015-05-06 | 2,668,570 | — | $0 | 2,668,570 | SEC↗ |
| WEBER ECKARD | Director | A Award | 2015-05-04 | 2015-05-07 | 243,726 | — | $0 | 243,726 | SEC↗ |
| WEBER ECKARD | Director | A Award | 2015-05-04 | 2015-05-07 | 36,187 | — | $0 | 36,187 | SEC↗ |
| WEBER ECKARD | Director | A Award | 2015-05-04 | 2015-05-07 | 3,553,322 | — | $0 | 3,553,322 | SEC↗ |
| WEBER ECKARD | Director | A Award | 2015-05-04 | 2015-05-07 | 47,613 | — | $0 | 47,613 | SEC↗ |
| WEBER ECKARD | Director | A Award | 2015-05-04 | 2015-05-07 | 243,726 | — | $0 | 243,726 | SEC↗ |