Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$0
Insiders on file
41
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Brown Scott B. | Chief Financial Officer | 12 | $25.1K | $0 | 2024-03-12 |
| THEUER CHARLES | President and CEO | 72 | $749.2K | $216.8K | 2024-03-12 |
| Opaleye Management Inc. | 10% Owner | 87 | $7.40M | $1.38M | 2023-11-10 |
| Johnson-Pratt Lisa | Director | 4 | $0 | $0 | 2023-04-19 |
| Lam Carol C. | Director | 3 | $0 | $0 | 2023-04-19 |
| Twiford J Rainer | Director | 12 | $0 | $0 | 2023-04-19 |
| WORLAND STEPHEN T | Director | 11 | $0 | $0 | 2023-04-19 |
| LARUE WILLIAM R | Director | 13 | $25.0K | $6.9K | 2023-04-19 |
| MATTINGLY MARTIN A | Director | 11 | $0 | $0 | 2023-04-19 |
| PELLETIER SAUNDRA L | Director | 8 | $36.2K | $0 | 2023-04-19 |
| Adams Bonne J. | Chief Operating Officer | 1 | $0 | $0 | 2023-02-01 |
| WIGGINS MARK C | Chief Business Officer | 8 | $59.6K | $0 | 2022-01-28 |
| Shahrestani Neil | 10% Owner | 5 | $6.06M | $0 | 2020-12-30 |
| Ikarian Healthcare Fund GP, L.P. | 10% Owner | 3 | $173.2K | $0 | 2020-11-11 |
| Ikarian Healthcare Master Fund, L.P. | 10% Owner | 4 | $1.06M | $0 | 2020-09-11 |
| Walker Paul Edward | Director | 6 | $0 | $0 | 2020-06-10 |
| Puissance Capital Management LP | 10% Owner | 2 | $0 | $1.13M | 2019-12-09 |
| Puissance Life Science Opportunities Fund VI | 10% Owner | 2 | $4.9K | $5.2K | 2018-11-29 |
| Puissance Cross-Border Opportunities V LLC | 10% Owner | 2 | $4.9K | $5.2K | 2018-11-29 |
| Wang Theodore T | Director, 10% Owner | 2 | $0 | $0 | 2018-06-13 |
| NEA 14 GP, LTD | 10% Owner | 4 | $4.01M | $0 | 2018-03-27 |
| NEA Partners 14, L.P. | 10% Owner | 9 | $13.01M | $0 | 2018-03-27 |
| Viswanathan Ravi | 10% Owner | 6 | $12.00M | $0 | 2018-03-27 |
| BASKETT FOREST | 10% Owner | 6 | $12.00M | $0 | 2018-03-27 |
| SANDELL SCOTT D | 10% Owner | 6 | $12.00M | $0 | 2018-03-27 |
| BARRIS PETER J | 10% Owner | 6 | $12.00M | $0 | 2018-03-27 |
| BITAR PATRICIA L | CFO | 6 | $0 | $0 | 2018-02-21 |
| LOGAN H CASEY | Chief Business Officer | 8 | $0 | $86.7K | 2018-01-22 |
| Florence Anthony A. Jr. | 10% Owner | 4 | $10.00M | $0 | 2016-11-29 |
| Sonsini Peter W. | 10% Owner | 4 | $10.00M | $0 | 2016-11-29 |
| KOLLURI KRISHNA KITTU | 10% Owner | 4 | $10.00M | $0 | 2016-11-29 |
| KERINS PATRICK J | 10% Owner | 4 | $10.00M | $0 | 2016-11-29 |
| MOTT DAVID M | 10% Owner | 4 | $10.00M | $0 | 2016-11-29 |
| BARRETT M JAMES | 10% Owner | 4 | $10.00M | $0 | 2016-11-29 |
| SHAZER RONALD L | Chief Medical Officer | 2 | $0 | $7.5K | 2016-06-03 |
| JAFCO Super V3 Investment Limited Partnership | 10% Owner | 46 | $2.58M | $3.83M | 2015-10-16 |
| Brookline Tracon Investment Fund II, LLC | 10% Owner | 2 | $0 | $0 | 2015-07-30 |
| New Enterprise Associates 14, L.P. | 10% Owner | 3 | $5.00M | $0 | 2015-02-04 |
| CSA Biotechnology Fund II, LLC | 10% Owner | 3 | $0 | $0 | 2015-02-04 |
| Weller Harry R | 10% Owner | 3 | $5.00M | $0 | 2015-02-04 |
| DRANT RYAN D | 10% Owner | 3 | $5.00M | $0 | 2015-02-04 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| THEUER CHARLES | PRESIDENT AND CEO | A Award deriv | 2024-03-12 | 2024-03-13 | 518,300 | — | $0 | 518,300 | SEC↗ |
| Brown Scott B. | CHIEF FINANCIAL OFFICER | A Award deriv | 2024-03-12 | 2024-03-13 | 224,800 | — | $0 | 224,800 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2023-11-10 | 2023-11-14 | 4,324,008 | $0.29 | $1.25M | 0 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2023-11-10 | 2023-11-14 | 440,000 | $0.29 | $127.6K | 0 | SEC↗ |
| THEUER CHARLES | PRESIDENT AND CEO | A Award | 2023-10-20 | 2024-03-13 | 3,500 | $0.13 | $455 | 406,417 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2023-04-27 | 2023-04-28 | 47,000 | $0.75 | $35.3K | 399,417 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2023-04-26 | 2023-04-28 | 3,999 | $0.66 | $2.6K | 352,417 | SEC↗ |
| THEUER CHARLES | PRESIDENT AND CEO | A Award | 2023-04-20 | 2024-03-13 | 3,500 | $0.14 | $490 | 402,917 | SEC↗ |
| Brown Scott B. | CHIEF FINANCIAL OFFICER | A Award | 2023-04-20 | 2024-03-13 | 3,500 | $0.14 | $490 | 25,128 | SEC↗ |
| Twiford J Rainer | Director | A Award deriv | 2023-04-19 | 2023-04-21 | 18,000 | — | $0 | 18,000 | SEC↗ |
| LARUE WILLIAM R | Director | A Award deriv | 2023-04-19 | 2023-04-21 | 18,000 | — | $0 | 18,000 | SEC↗ |
| WORLAND STEPHEN T | Director | A Award deriv | 2023-04-19 | 2023-04-21 | 18,000 | — | $0 | 18,000 | SEC↗ |
| MATTINGLY MARTIN A | Director | A Award deriv | 2023-04-19 | 2023-04-21 | 18,000 | — | $0 | 18,000 | SEC↗ |
| PELLETIER SAUNDRA L | Director | A Award deriv | 2023-04-19 | 2023-04-21 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Lam Carol C. | Director | A Award deriv | 2023-04-19 | 2023-04-21 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Johnson-Pratt Lisa | Director | A Award deriv | 2023-04-19 | 2023-04-21 | 18,000 | — | $0 | 18,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2023-03-09 | 2023-03-13 | 174,508 | $1.38 | $240.8K | 4,324,508 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2023-03-01 | 2023-03-02 | 4,800 | $1.52 | $7.3K | 344,918 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2023-02-28 | 2023-03-02 | 200 | $1.52 | $304 | 340,118 | SEC↗ |
| THEUER CHARLES | President and CEO | A Award deriv | 2023-02-01 | 2023-02-03 | 332,000 | — | $0 | 332,000 | SEC↗ |
| Brown Scott B. | Chief Financial Officer | A Award deriv | 2023-02-01 | 2023-02-03 | 144,000 | — | $0 | 144,000 | SEC↗ |
| Adams Bonne J. | Chief Operating Officer | A Award deriv | 2023-02-01 | 2023-02-09 | 99,000 | — | $0 | 99,000 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2023-01-18 | 2023-01-19 | 6,800 | $1.62 | $11.0K | 339,918 | SEC↗ |
| Brown Scott B. | Chief Financial Officer | P Buy | 2022-12-29 | 2023-01-03 | 3,500 | $1.49 | $5.2K | 21,628 | SEC↗ |
| LARUE WILLIAM R | Director | S Sale | 2022-12-21 | 2023-01-19 | 120 | $1.26 | $151 | 7,763 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-12-14 | 2022-12-15 | 23,000 | $1.29 | $29.7K | 333,118 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-12-14 | 2022-12-16 | 140,000 | $1.26 | $176.4K | 4,150,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-12-14 | 2022-12-16 | 27,500 | $1.24 | $34.1K | 440,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | X Exercise deriv | 2022-12-06 | 2022-12-08 | 221,539 | $0.01 | $2.2K | 1,667,974 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | S Sale | 2022-12-06 | 2022-12-08 | 1,539 | $1.44 | $2.2K | 4,010,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | X Exercise | 2022-12-06 | 2022-12-08 | 221,539 | $0.01 | $2.2K | 4,011,539 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-11-18 | 2022-11-22 | 13,900 | $1.41 | $19.6K | 310,118 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-11-03 | 2022-11-04 | 9,200 | $1.52 | $14.0K | 296,218 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-11-02 | 2022-11-03 | 6,000 | $1.59 | $9.5K | 287,018 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-10-18 | 2022-10-19 | 10,000 | $1.65 | $16.5K | 3,790,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-10-18 | 2022-10-19 | 2,500 | $1.65 | $4.1K | 4,125,000 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-10-07 | 2022-10-11 | 5,000 | $1.77 | $8.8K | 277,518 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-10-03 | 2022-10-05 | 5,000 | $1.67 | $8.3K | 272,518 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-09-29 | 2022-10-03 | 9,400 | $1.74 | $16.4K | 410,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-09-27 | 2022-09-28 | 1,700 | $1.69 | $2.9K | 400,600 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-09-22 | 2022-09-22 | 13,900 | $1.73 | $24.0K | 398,900 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-09-22 | 2022-09-22 | 3,411 | $1.73 | $5.9K | 3,780,000 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-09-22 | 2022-09-26 | 5,000 | $1.76 | $8.8K | 267,518 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-09-20 | 2022-09-20 | 10,000 | $1.85 | $18.5K | 385,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-09-19 | 2022-09-19 | 5,000 | $1.87 | $9.3K | 375,000 | SEC↗ |
| Brown Scott B. | Chief Financial Officer | P Buy | 2022-09-12 | 2022-09-14 | 2,500 | $2.02 | $5.0K | 14,628 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-07-26 | 2022-07-26 | 2,254 | $1.72 | $3.9K | 370,000 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-07-22 | 2022-07-25 | 4,500 | $1.85 | $8.3K | 262,518 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-07-15 | 2022-07-15 | 11,826 | $1.78 | $21.1K | 367,746 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-07-14 | 2022-07-14 | 7,187 | $1.81 | $13.0K | 355,920 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-07-13 | 2022-07-14 | 3,000 | $1.84 | $5.5K | 258,018 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-07-12 | 2022-07-14 | 3,000 | $1.87 | $5.6K | 255,018 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-06-24 | 2022-06-27 | 11,419 | $1.39 | $15.9K | 348,733 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-06-21 | 2022-06-23 | 841,989 | $1.31 | $1.10M | 3,776,589 | SEC↗ |
| Johnson-Pratt Lisa | Director | A Award deriv | 2022-06-14 | 2022-06-16 | 15,750 | — | $0 | 15,750 | SEC↗ |
| PELLETIER SAUNDRA L | Director | A Award deriv | 2022-06-14 | 2022-06-16 | 15,750 | — | $0 | 15,750 | SEC↗ |
| Lam Carol C. | Director | A Award deriv | 2022-06-14 | 2022-06-16 | 15,750 | — | $0 | 15,750 | SEC↗ |
| MATTINGLY MARTIN A | Director | A Award deriv | 2022-06-14 | 2022-06-16 | 15,750 | — | $0 | 15,750 | SEC↗ |
| LARUE WILLIAM R | Director | A Award deriv | 2022-06-14 | 2022-06-16 | 15,750 | — | $0 | 15,750 | SEC↗ |
| WORLAND STEPHEN T | Director | A Award deriv | 2022-06-14 | 2022-06-16 | 15,750 | — | $0 | 15,750 | SEC↗ |
| Twiford J Rainer | Director | A Award deriv | 2022-06-14 | 2022-06-16 | 15,750 | — | $0 | 15,750 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-05-10 | 2022-05-10 | 8,500 | $1.76 | $15.0K | 2,934,600 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-05-10 | 2022-05-10 | 1,200 | $1.76 | $2.1K | 337,314 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-05-09 | 2022-05-11 | 10,000 | $1.85 | $18.5K | 252,018 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-05-06 | 2022-05-10 | 2,500 | $1.97 | $4.9K | 242,018 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-04-29 | 2022-05-03 | 5,000 | $1.97 | $9.8K | 239,518 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-25 | 2022-04-25 | 777 | $2.18 | $1.7K | 335,114 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-25 | 2022-04-25 | 10,000 | $2.18 | $21.8K | 2,920,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-22 | 2022-04-25 | 4,296 | $2.24 | $9.6K | 334,337 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-22 | 2022-04-25 | 37,704 | $2.24 | $84.5K | 2,910,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-22 | 2022-04-29 | 1,000 | $1.98 | $2.0K | 336,114 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-22 | 2022-04-29 | 6,100 | $1.98 | $12.1K | 2,926,100 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-04-21 | 2022-04-25 | 4,500 | $2.30 | $10.3K | 234,518 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-14 | 2022-04-14 | 10,000 | $2.50 | $25.0K | 2,872,296 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-14 | 2022-04-14 | 2,696 | $2.50 | $6.7K | 330,041 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-13 | 2022-04-14 | 5,000 | $2.50 | $12.5K | 2,862,296 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-13 | 2022-04-14 | 2,345 | $2.50 | $5.9K | 327,345 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-12 | 2022-04-12 | 13,098 | $2.48 | $32.5K | 2,857,296 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-12 | 2022-04-12 | 5,000 | $2.48 | $12.4K | 325,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-11 | 2022-04-12 | 6,463 | $2.42 | $15.6K | 2,844,198 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-04-11 | 2022-04-12 | 2,637 | $2.42 | $6.4K | 320,000 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-04-08 | 2022-04-12 | 2,000 | $2.50 | $5.0K | 226,518 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-03-30 | 2022-04-01 | 4,000 | $2.70 | $10.8K | 224,518 | SEC↗ |
| Brown Scott B. | Chief Financial Officer | P Buy | 2022-03-29 | 2022-03-30 | 1,000 | $2.82 | $2.8K | 8,628 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2022-03-21 | 2022-03-23 | 1,200 | $2.45 | $2.9K | 220,518 | SEC↗ |
| Brown Scott B. | Chief Financial Officer | A Award deriv | 2022-01-28 | 2022-02-01 | 80,000 | — | $0 | 80,000 | SEC↗ |
| THEUER CHARLES | President and CEO | A Award deriv | 2022-01-28 | 2022-02-01 | 265,000 | — | $0 | 265,000 | SEC↗ |
| WIGGINS MARK C | Chief Business Officer | A Award deriv | 2022-01-28 | 2022-02-01 | 80,000 | — | $0 | 80,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-01-28 | 2022-01-31 | 500 | $2.20 | $1.1K | 2,820,500 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-01-24 | 2022-01-24 | 15,000 | $2.05 | $30.7K | 2,835,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-01-24 | 2022-01-24 | 2,363 | $2.05 | $4.8K | 317,363 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-01-21 | 2022-01-24 | 5,000 | $2.19 | $10.9K | 315,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-01-21 | 2022-01-24 | 30,000 | $2.19 | $65.7K | 2,820,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-01-20 | 2022-01-21 | 20,000 | $2.25 | $45.0K | 2,790,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-01-20 | 2022-01-21 | 1,312 | $2.25 | $3.0K | 310,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-01-19 | 2022-01-21 | 20,000 | $2.24 | $44.8K | 2,770,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2022-01-19 | 2022-01-21 | 3,688 | $2.24 | $8.3K | 308,688 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-29 | 2021-12-29 | 20,000 | $2.51 | $50.2K | 305,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-29 | 2021-12-29 | 32,325 | $2.51 | $81.1K | 2,750,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-28 | 2021-12-29 | 125 | $2.63 | $330 | 2,717,675 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-28 | 2021-12-29 | 20,000 | $2.63 | $52.6K | 285,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-27 | 2021-12-29 | 12,325 | $2.92 | $36.0K | 265,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-27 | 2021-12-29 | 75,000 | $2.92 | $219.0K | 2,592,371 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-15 | 2021-12-16 | 1,964 | $2.43 | $4.8K | 252,675 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-15 | 2021-12-16 | 20,000 | $2.43 | $48.6K | 2,517,371 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-14 | 2021-12-15 | 35,000 | $2.53 | $88.5K | 2,497,371 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-14 | 2021-12-15 | 7,000 | $2.53 | $17.7K | 250,711 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-13 | 2021-12-15 | 14,000 | $2.64 | $37.0K | 2,462,371 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-13 | 2021-12-15 | 1,204 | $2.64 | $3.2K | 243,711 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-06 | 2021-12-07 | 2,733 | $2.26 | $6.2K | 242,507 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-06 | 2021-12-07 | 20,000 | $2.26 | $45.2K | 2,448,371 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-03 | 2021-12-07 | 80,000 | $2.30 | $184.0K | 2,428,371 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-03 | 2021-12-07 | 9,274 | $2.30 | $21.3K | 239,774 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-02 | 2021-12-03 | 10,000 | $2.35 | $23.5K | 2,348,371 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-02 | 2021-12-03 | 500 | $2.35 | $1.2K | 230,500 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-01 | 2021-12-03 | 45,000 | $2.40 | $108.0K | 2,338,371 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2021-12-01 | 2021-12-03 | 5,000 | $2.40 | $12.0K | 230,000 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2021-11-19 | 2021-11-22 | 3,500 | $2.82 | $9.9K | 219,318 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2021-11-18 | 2021-11-22 | 681 | $2.88 | $2.0K | 215,818 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2021-11-05 | 2021-11-09 | 3,000 | $3.42 | $10.3K | 215,137 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2021-11-05 | 2021-11-09 | 1,000 | $3.41 | $3.4K | 212,137 | SEC↗ |
| Lam Carol C. | Director | A Award deriv | 2021-10-12 | 2021-10-13 | 21,000 | — | $0 | 21,000 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2021-08-16 | 2021-08-18 | 3,000 | $3.56 | $10.7K | 207,732 | SEC↗ |
| Brown Scott B. | Chief Financial Officer | P Buy | 2021-08-13 | 2021-08-17 | 1,000 | $3.69 | $3.7K | 7,628 | SEC↗ |
| LARUE WILLIAM R | Director | P Buy | 2021-07-26 | 2021-07-27 | 6,545 | $3.82 | $25.0K | 7,883 | SEC↗ |
| PELLETIER SAUNDRA L | Director | P Buy | 2021-07-26 | 2021-07-27 | 6,545 | $3.82 | $25.0K | 12,045 | SEC↗ |
| WORLAND STEPHEN T | Director | A Award deriv | 2021-06-10 | 2021-06-24 | 10,500 | — | $0 | 10,500 | SEC↗ |
| Twiford J Rainer | Director | A Award deriv | 2021-06-10 | 2021-06-24 | 10,500 | — | $0 | 10,500 | SEC↗ |
| PELLETIER SAUNDRA L | Director | A Award deriv | 2021-06-10 | 2021-06-24 | 10,500 | — | $0 | 10,500 | SEC↗ |
| LARUE WILLIAM R | Director | A Award deriv | 2021-06-10 | 2021-06-24 | 10,500 | — | $0 | 10,500 | SEC↗ |
| MATTINGLY MARTIN A | Director | A Award deriv | 2021-06-10 | 2021-06-24 | 10,500 | — | $0 | 10,500 | SEC↗ |
| Johnson-Pratt Lisa | Director | A Award deriv | 2021-06-10 | 2021-06-24 | 10,500 | — | $0 | 10,500 | SEC↗ |
| Brown Scott B. | Chief Financial Officer | P Buy | 2021-03-08 | 2021-03-09 | 1,000 | $8.30 | $8.3K | 3,128 | SEC↗ |
| Johnson-Pratt Lisa | Director | A Award deriv | 2021-03-02 | 2021-03-08 | 21,000 | — | $0 | 21,000 | SEC↗ |
| WIGGINS MARK C | Chief Business Officer | A Award deriv | 2021-01-29 | 2021-02-02 | 55,000 | — | $0 | 55,000 | SEC↗ |
| THEUER CHARLES | President and CEO | A Award deriv | 2021-01-29 | 2021-02-02 | 180,000 | — | $0 | 180,000 | SEC↗ |
| Brown Scott B. | Chief Accounting Officer (PA | A Award deriv | 2021-01-29 | 2021-02-02 | 55,000 | — | $0 | 55,000 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2021-01-27 | 2021-01-28 | 11,000 | $8.98 | $98.8K | 201,232 | SEC↗ |
| Shahrestani Neil | 10% Owner | P Buy | 2020-12-30 | 2020-12-30 | 520,291 | $9.61 | $5.00M | 2,716,840 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-12-29 | 2020-12-30 | 1,000 | $9.98 | $10.0K | 190,232 | SEC↗ |
| WIGGINS MARK C | Chief Business Officer | P Buy | 2020-12-29 | 2020-12-30 | 3 | $10.56 | $32 | 13,700 | SEC↗ |
| WIGGINS MARK C | Chief Business Officer | P Buy | 2020-12-29 | 2020-12-30 | 997 | $10.57 | $10.5K | 13,697 | SEC↗ |
| Ikarian Healthcare Fund GP, L. | 10% Owner | P Buy | 2020-11-11 | 2020-11-12 | 5,000 | $7.53 | $37.6K | 2,196,549 | SEC↗ |
| Ikarian Healthcare Fund GP, L. | 10% Owner | P Buy | 2020-10-30 | 2020-11-12 | 21,300 | $4.64 | $98.8K | 2,191,549 | SEC↗ |
| Ikarian Healthcare Fund GP, L. | 10% Owner | P Buy | 2020-10-29 | 2020-11-12 | 7,700 | $4.77 | $36.7K | 2,170,249 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-10-21 | 2020-10-23 | 2,000 | $4.38 | $8.8K | 189,232 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-10-21 | 2020-10-23 | 5,656 | $4.40 | $24.9K | 1,797,094 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-10-21 | 2020-10-23 | 3,000 | $4.40 | $13.2K | 225,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-09-24 | 2020-09-25 | 534 | $4.44 | $2.4K | 228,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-09-24 | 2020-09-25 | 21,000 | $4.44 | $93.2K | 1,785,438 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-09-23 | 2020-09-25 | 107 | $4.72 | $505 | 186,882 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-09-23 | 2020-09-25 | 4,893 | $4.72 | $23.1K | 186,775 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-09-23 | 2020-09-25 | 2,200 | $4.83 | $10.6K | 227,466 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-09-23 | 2020-09-25 | 55,000 | $4.83 | $265.6K | 1,764,438 | SEC↗ |
| Ikarian Healthcare Master Fund | 10% Owner | P Buy | 2020-09-11 | 2020-09-15 | 78,201 | $3.93 | $307.3K | 2,162,549 | SEC↗ |
| Shahrestani Neil | 10% Owner | P Buy | 2020-09-11 | 2020-09-17 | 78,201 | $3.93 | $307.3K | 2,162,549 | SEC↗ |
| WIGGINS MARK C | Chief Business Officer | P Buy | 2020-09-10 | 2020-09-14 | 7,000 | $4.14 | $29.0K | 12,350 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-09-09 | 2020-09-09 | 2,500 | $3.47 | $8.7K | 225,266 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-09-09 | 2020-09-09 | 45,000 | $3.47 | $156.2K | 1,709,438 | SEC↗ |
| Ikarian Healthcare Master Fund | 10% Owner | P Buy | 2020-09-09 | 2020-09-15 | 79,415 | $3.49 | $277.2K | 2,084,348 | SEC↗ |
| Shahrestani Neil | 10% Owner | P Buy | 2020-09-09 | 2020-09-17 | 79,415 | $3.49 | $277.2K | 2,084,348 | SEC↗ |
| Ikarian Healthcare Master Fund | 10% Owner | P Buy | 2020-09-08 | 2020-09-15 | 13,244 | $2.90 | $38.4K | 2,004,933 | SEC↗ |
| Shahrestani Neil | 10% Owner | P Buy | 2020-09-08 | 2020-09-17 | 13,244 | $2.90 | $38.4K | 2,004,933 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-09-04 | 2020-09-09 | 5,000 | $2.60 | $13.0K | 176,882 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-09-04 | 2020-09-09 | 5,000 | $2.55 | $12.8K | 181,882 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-09-04 | 2020-09-09 | 8,492 | $2.88 | $24.5K | 1,664,438 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-09-04 | 2020-09-09 | 566 | $2.88 | $1.6K | 222,766 | SEC↗ |
| Ikarian Healthcare Master Fund | 10% Owner | P Buy | 2020-09-04 | 2020-09-15 | 151,611 | $2.87 | $435.1K | 1,991,689 | SEC↗ |
| Shahrestani Neil | 10% Owner | P Buy | 2020-09-04 | 2020-09-17 | 151,611 | $2.87 | $435.1K | 1,991,689 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-09-02 | 2020-09-03 | 4,800 | $2.35 | $11.3K | 222,200 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-09-02 | 2020-09-03 | 115,000 | $2.35 | $270.3K | 1,655,946 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-09-01 | 2020-09-03 | 38,600 | $2.04 | $78.7K | 1,540,946 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-09-01 | 2020-09-03 | 1,400 | $2.04 | $2.9K | 217,400 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy deriv | 2020-08-31 | 2020-08-31 | 1,358,993 | $1.66 | $2.26M | 1,358,993 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-08-31 | 2020-08-31 | 150,000 | $1.84 | $276.0K | 1,502,346 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-08-31 | 2020-08-31 | 6,000 | $1.84 | $11.0K | 216,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-08-31 | 2020-08-31 | 146,150 | $1.67 | $244.1K | 1,352,346 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-08-28 | 2020-08-31 | 60,000 | $1.78 | $106.8K | 210,000 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-08-27 | 2020-08-31 | 35,408 | $1.71 | $60.5K | 1,206,196 | SEC↗ |
| Opaleye Management Inc. | 10% Owner | P Buy | 2020-08-27 | 2020-08-31 | 147,946 | $1.71 | $253.0K | 150,000 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-08-21 | 2020-08-25 | 5,325 | $1.56 | $8.3K | 171,882 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-08-20 | 2020-08-24 | 30,000 | $1.58 | $47.4K | 166,557 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-08-18 | 2020-08-18 | 44,743 | $1.63 | $72.9K | 136,557 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-08-14 | 2020-08-18 | 100 | $1.70 | $170 | 91,814 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-08-13 | 2020-08-14 | 5,000 | $1.65 | $8.3K | 91,714 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-08-12 | 2020-08-14 | 5,000 | $1.67 | $8.3K | 76,714 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-08-12 | 2020-08-14 | 10,000 | $1.79 | $17.9K | 86,714 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-06-24 | 2020-06-25 | 9,895 | $1.90 | $18.8K | 71,714 | SEC↗ |
| PELLETIER SAUNDRA L | Director | P Buy | 2020-06-15 | 2020-06-16 | 3,000 | $2.07 | $6.2K | 5,500 | SEC↗ |
| PELLETIER SAUNDRA L | Director | P Buy | 2020-06-11 | 2020-06-16 | 2,500 | $2.00 | $5.0K | 2,500 | SEC↗ |
| PELLETIER SAUNDRA L | Director | A Award deriv | 2020-06-10 | 2020-06-16 | 4,500 | — | $0 | 4,500 | SEC↗ |
| Walker Paul Edward | Director | A Award deriv | 2020-06-10 | 2020-06-16 | 4,500 | — | $0 | 4,500 | SEC↗ |
| WORLAND STEPHEN T | Director | A Award deriv | 2020-06-10 | 2020-06-16 | 4,500 | — | $0 | 4,500 | SEC↗ |
| Twiford J Rainer | Director | A Award deriv | 2020-06-10 | 2020-06-16 | 4,500 | — | $0 | 4,500 | SEC↗ |
| MATTINGLY MARTIN A | Director | A Award deriv | 2020-06-10 | 2020-06-16 | 4,500 | — | $0 | 4,500 | SEC↗ |
| LARUE WILLIAM R | Director | A Award deriv | 2020-06-10 | 2020-06-16 | 4,500 | — | $0 | 4,500 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-05-22 | 2020-05-26 | 10,000 | $1.90 | $19.0K | 61,227 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-05-22 | 2020-05-26 | 592 | $1.89 | $1.1K | 61,819 | SEC↗ |
| PELLETIER SAUNDRA L | Director | A Award deriv | 2020-03-16 | 2020-03-18 | 6,000 | — | $0 | 6,000 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-03-13 | 2020-03-13 | 4,100 | $1.13 | $4.6K | 50,877 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-03-12 | 2020-03-12 | 5,000 | $1.17 | $5.8K | 46,777 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-03-12 | 2020-03-12 | 5,000 | $1.19 | $6.0K | 41,777 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-03-11 | 2020-03-12 | 5,000 | $1.71 | $8.6K | 31,777 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-03-11 | 2020-03-12 | 5,000 | $1.66 | $8.3K | 36,777 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2020-03-10 | 2020-03-10 | 10,000 | $1.87 | $18.7K | 26,777 | SEC↗ |
| THEUER CHARLES | President and CEO | A Award deriv | 2020-01-31 | 2020-02-04 | 123,200 | — | $0 | 123,200 | SEC↗ |
| WIGGINS MARK C | Chief Business Officer | A Award deriv | 2020-01-31 | 2020-02-04 | 22,000 | — | $0 | 22,000 | SEC↗ |
| Brown Scott B. | Chief Accounting Officer (PA | A Award deriv | 2020-01-31 | 2020-02-04 | 22,000 | — | $0 | 22,000 | SEC↗ |
| WIGGINS MARK C | Chief Business Officer | P Buy | 2020-01-23 | 2020-01-24 | 5,000 | $4.02 | $20.1K | 5,000 | SEC↗ |
| THEUER CHARLES | President and CEO | F Tax w/h | 2020-01-22 | 2020-01-24 | 929 | $3.76 | $3.5K | 16,777 | SEC↗ |
| Brown Scott B. | Chief Accounting Officer (PA | F Tax w/h | 2020-01-22 | 2020-01-24 | 18 | $3.76 | $68 | 1,428 | SEC↗ |
| Puissance Capital Management L | 10% Owner | S Sale | 2019-12-09 | 2019-12-11 | 340,134 | $2.92 | $993.2K | 76,048 | SEC↗ |
| Puissance Capital Management L | 10% Owner | S Sale | 2019-12-05 | 2019-12-11 | 43,996 | $3.05 | $134.2K | 416,182 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2019-08-09 | 2019-08-12 | 50,000 | $0.45 | $22.5K | 173,565 | SEC↗ |
| WORLAND STEPHEN T | Director | A Award deriv | 2019-06-13 | 2019-06-17 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Twiford J Rainer | Director | A Award deriv | 2019-06-13 | 2019-06-17 | 15,000 | — | $0 | 15,000 | SEC↗ |
| MATTINGLY MARTIN A | Director | A Award deriv | 2019-06-13 | 2019-06-17 | 15,000 | — | $0 | 15,000 | SEC↗ |
| LARUE WILLIAM R | Director | A Award deriv | 2019-06-13 | 2019-06-17 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Walker Paul Edward | Director | A Award deriv | 2019-06-13 | 2019-06-17 | 15,000 | — | $0 | 15,000 | SEC↗ |
| THEUER CHARLES | President and CEO | F Tax w/h | 2019-01-22 | 2019-01-23 | 9,290 | $1.04 | $9.7K | 123,565 | SEC↗ |
| THEUER CHARLES | President and CEO | P Buy | 2018-12-21 | 2018-12-21 | 49,000 | $0.66 | $32.3K | 132,855 | SEC↗ |
| Puissance Life Science Opportu | 10% Owner | P Buy | 2018-11-29 | 2018-12-03 | 4,326 | $1.13 | $4.9K | 4,606,094 | SEC↗ |
| Puissance Life Science Opportu | 10% Owner | S Sale | 2018-11-29 | 2018-12-03 | 4,326 | $1.21 | $5.2K | 4,601,768 | SEC↗ |
| Puissance Cross-Border Opportu | 10% Owner | P Buy | 2018-11-29 | 2018-12-03 | 4,326 | $1.13 | $4.9K | 4,606,094 | SEC↗ |
| Puissance Cross-Border Opportu | 10% Owner | S Sale | 2018-11-29 | 2018-12-03 | 4,326 | $1.21 | $5.2K | 4,601,768 | SEC↗ |
| WORLAND STEPHEN T | Director | A Award deriv | 2018-06-13 | 2018-06-13 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Twiford J Rainer | Director | A Award deriv | 2018-06-13 | 2018-06-13 | 15,000 | — | $0 | 15,000 | SEC↗ |
| LARUE WILLIAM R | Director | A Award deriv | 2018-06-13 | 2018-06-13 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Walker Paul Edward | Director | A Award deriv | 2018-06-13 | 2018-06-13 | 15,000 | — | $0 | 15,000 | SEC↗ |
| MATTINGLY MARTIN A | Director | A Award deriv | 2018-06-13 | 2018-06-13 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Wang Theodore T | Director, 10% Owner | A Award deriv | 2018-06-13 | 2018-06-13 | 15,000 | — | $0 | 15,000 | SEC↗ |
| WIGGINS MARK C | Chief Business Officer | A Award deriv | 2018-05-29 | 2018-05-30 | 280,000 | — | $0 | 280,000 | SEC↗ |
| Wang Theodore T | Director, 10% Owner | A Award deriv | 2018-04-06 | 2018-04-09 | 25,000 | — | $0 | 25,000 | SEC↗ |
| NEA Partners 14, L.P. | 10% Owner | P Buy deriv | 2018-03-27 | 2018-03-27 | 707,964 | $0.13 | $92.0K | 707,964 | SEC↗ |
| NEA 14 GP, LTD | 10% Owner | P Buy deriv | 2018-03-27 | 2018-03-27 | 707,964 | $0.13 | $92.0K | 707,964 | SEC↗ |
| BARRIS PETER J | 10% Owner | P Buy deriv | 2018-03-27 | 2018-03-27 | 707,964 | $0.13 | $92.0K | 707,964 | SEC↗ |
| BASKETT FOREST | 10% Owner | P Buy deriv | 2018-03-27 | 2018-03-27 | 707,964 | $0.13 | $92.0K | 707,964 | SEC↗ |
| NEA Partners 14, L.P. | 10% Owner | P Buy deriv | 2018-03-27 | 2018-03-27 | 707,964 | $0.13 | $92.0K | 707,964 | SEC↗ |
| NEA Partners 14, L.P. | 10% Owner | P Buy deriv | 2018-03-27 | 2018-03-27 | 707,964 | $0.13 | $92.0K | 707,964 | SEC↗ |
| NEA 14 GP, LTD | 10% Owner | P Buy deriv | 2018-03-27 | 2018-03-27 | 707,964 | $0.13 | $92.0K | 707,964 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | P Buy deriv | 2018-03-27 | 2018-03-27 | 707,964 | $0.13 | $92.0K | 707,964 | SEC↗ |
| NEA Partners 14, L.P. | 10% Owner | P Buy deriv | 2018-03-27 | 2018-03-27 | 707,964 | $0.13 | $92.0K | 707,964 | SEC↗ |
| Viswanathan Ravi | 10% Owner | P Buy deriv | 2018-03-27 | 2018-03-27 | 707,964 | $0.13 | $92.0K | 707,964 | SEC↗ |
| NEA Partners 14, L.P. | 10% Owner | P Buy | 2018-03-27 | 2018-03-27 | 707,964 | $2.70 | $1.91M | 3,466,003 | SEC↗ |
| NEA 14 GP, LTD | 10% Owner | P Buy | 2018-03-27 | 2018-03-27 | 707,964 | $2.70 | $1.91M | 3,466,003 | SEC↗ |
| BARRIS PETER J | 10% Owner | P Buy | 2018-03-27 | 2018-03-27 | 707,964 | $2.70 | $1.91M | 3,466,003 | SEC↗ |
| BASKETT FOREST | 10% Owner | P Buy | 2018-03-27 | 2018-03-27 | 707,964 | $2.70 | $1.91M | 3,466,003 | SEC↗ |
| NEA Partners 14, L.P. | 10% Owner | P Buy | 2018-03-27 | 2018-03-27 | 707,964 | $2.70 | $1.91M | 3,466,003 | SEC↗ |
| NEA Partners 14, L.P. | 10% Owner | P Buy | 2018-03-27 | 2018-03-27 | 707,964 | $2.70 | $1.91M | 3,466,003 | SEC↗ |
| NEA 14 GP, LTD | 10% Owner | P Buy | 2018-03-27 | 2018-03-27 | 707,964 | $2.70 | $1.91M | 3,466,003 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | P Buy | 2018-03-27 | 2018-03-27 | 707,964 | $2.70 | $1.91M | 3,466,003 | SEC↗ |
| NEA Partners 14, L.P. | 10% Owner | P Buy | 2018-03-27 | 2018-03-27 | 707,964 | $2.70 | $1.91M | 3,466,003 | SEC↗ |
| Viswanathan Ravi | 10% Owner | P Buy | 2018-03-27 | 2018-03-27 | 707,964 | $2.70 | $1.91M | 3,466,003 | SEC↗ |
| THEUER CHARLES | President and CEO | A Award deriv | 2018-02-21 | 2018-02-23 | 225,000 | — | $0 | 225,000 | SEC↗ |
| BITAR PATRICIA L | CFO | A Award deriv | 2018-02-21 | 2018-02-23 | 95,000 | — | $0 | 95,000 | SEC↗ |
| BITAR PATRICIA L | CFO | F Tax w/h | 2018-01-22 | 2018-01-23 | 3,317 | $2.95 | $9.8K | 29,636 | SEC↗ |
| THEUER CHARLES | President and CEO | F Tax w/h | 2018-01-22 | 2018-01-23 | 9,290 | $2.95 | $27.4K | 76,855 | SEC↗ |
| LOGAN H CASEY | Chief Business Officer | F Tax w/h | 2018-01-22 | 2018-01-23 | 3,317 | $2.95 | $9.8K | 27,754 | SEC↗ |
| WORLAND STEPHEN T | Director | A Award deriv | 2017-06-15 | 2017-06-15 | 15,000 | — | $0 | 15,000 | SEC↗ |
| MATTINGLY MARTIN A | Director | A Award deriv | 2017-06-15 | 2017-06-15 | 15,000 | — | $0 | 15,000 | SEC↗ |
| LARUE WILLIAM R | Director | A Award deriv | 2017-06-15 | 2017-06-15 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Walker Paul Edward | Director | A Award deriv | 2017-06-15 | 2017-06-15 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Twiford J Rainer | Director | A Award deriv | 2017-06-15 | 2017-06-15 | 15,000 | — | $0 | 15,000 | SEC↗ |
| LARUE WILLIAM R | Director | S Sale | 2017-06-02 | 2017-06-05 | 2,500 | $2.69 | $6.7K | 13,388 | SEC↗ |
| BITAR PATRICIA L | CFO | F Tax w/h | 2017-01-23 | 2017-01-24 | 3,552 | $4.85 | $17.2K | 30,543 | SEC↗ |
| LOGAN H CASEY | Chief Business Officer | F Tax w/h | 2017-01-23 | 2017-01-24 | 3,552 | $4.85 | $17.2K | 31,071 | SEC↗ |
| THEUER CHARLES | President and CEO | A Award deriv | 2017-01-20 | 2017-01-24 | 190,000 | — | $0 | 190,000 | SEC↗ |
| BITAR PATRICIA L | CFO | A Award deriv | 2017-01-20 | 2017-01-24 | 55,000 | — | $0 | 55,000 | SEC↗ |
| LOGAN H CASEY | Chief Business Officer | A Award deriv | 2017-01-20 | 2017-01-24 | 55,000 | — | $0 | 55,000 | SEC↗ |
| NEA Partners 14, L.P. | 10% Owner | P Buy | 2016-11-29 | 2016-11-29 | 869,565 | $5.75 | $5.00M | 2,758,039 | SEC↗ |
| Viswanathan Ravi | 10% Owner | P Buy | 2016-11-29 | 2016-11-29 | 869,565 | $5.75 | $5.00M | 2,758,039 | SEC↗ |
| Sonsini Peter W. | 10% Owner | P Buy | 2016-11-29 | 2016-11-29 | 869,565 | $5.75 | $5.00M | 2,758,039 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | P Buy | 2016-11-29 | 2016-11-29 | 869,565 | $5.75 | $5.00M | 2,758,039 | SEC↗ |
| MOTT DAVID M | 10% Owner | P Buy | 2016-11-29 | 2016-11-29 | 869,565 | $5.75 | $5.00M | 2,758,039 | SEC↗ |
| KOLLURI KRISHNA KITTU | 10% Owner | P Buy | 2016-11-29 | 2016-11-29 | 869,565 | $5.75 | $5.00M | 2,758,039 | SEC↗ |
| KERINS PATRICK J | 10% Owner | P Buy | 2016-11-29 | 2016-11-29 | 869,565 | $5.75 | $5.00M | 2,758,039 | SEC↗ |
| Florence Anthony A. Jr. | 10% Owner | P Buy | 2016-11-29 | 2016-11-29 | 869,565 | $5.75 | $5.00M | 2,758,039 | SEC↗ |
| BASKETT FOREST | 10% Owner | P Buy | 2016-11-29 | 2016-11-29 | 869,565 | $5.75 | $5.00M | 2,758,039 | SEC↗ |
| BARRIS PETER J | 10% Owner | P Buy | 2016-11-29 | 2016-11-29 | 869,565 | $5.75 | $5.00M | 2,758,039 | SEC↗ |
| BARRETT M JAMES | 10% Owner | P Buy | 2016-11-29 | 2016-11-29 | 869,565 | $5.75 | $5.00M | 2,758,039 | SEC↗ |
| SHAZER RONALD L | Chief Medical Officer | S Sale | 2016-06-03 | 2016-06-07 | 1,003 | $7.48 | $7.5K | 335 | SEC↗ |
| LARUE WILLIAM R | Director | A Award | 2016-06-01 | 2016-06-02 | 7,500 | — | $0 | 15,888 | SEC↗ |
| MATTINGLY MARTIN A | Director | A Award | 2016-06-01 | 2016-06-02 | 7,500 | — | $0 | 7,500 | SEC↗ |
| WORLAND STEPHEN T | Director | A Award | 2016-06-01 | 2016-06-02 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Twiford J Rainer | Director | A Award | 2016-06-01 | 2016-06-02 | 7,500 | — | $0 | 7,500 | SEC↗ |
| Walker Paul Edward | Director | A Award | 2016-06-01 | 2016-06-02 | 7,500 | — | $0 | 7,500 | SEC↗ |
| THEUER CHARLES | President and CEO | F Tax w/h | 2016-01-23 | 2017-01-24 | 9,870 | $4.85 | $47.9K | 86,145 | SEC↗ |
| THEUER CHARLES | President and CEO | A Award | 2016-01-21 | 2016-01-25 | 90,900 | — | $0 | 93,400 | SEC↗ |
| BITAR PATRICIA L | CFO | A Award | 2016-01-21 | 2016-01-25 | 32,450 | — | $0 | 32,943 | SEC↗ |
| LOGAN H CASEY | Chief Business Officer | A Award | 2016-01-21 | 2016-01-25 | 32,450 | — | $0 | 33,550 | SEC↗ |
| JAFCO Super V3 Investment Limi | 10% Owner | S Sale | 2015-10-16 | 2015-10-19 | 1,500 | $9.90 | $14.8K | 1,497,053 | SEC↗ |
| JAFCO Super V3 Investment Limi | 10% Owner | S Sale | 2015-10-15 | 2015-10-15 | 5,300 | $10.16 | $53.8K | 1,498,553 | SEC↗ |
| JAFCO Super V3 Investment Limi | 10% Owner | S Sale | 2015-10-13 | 2015-10-13 | 1,720 | $10.01 | $17.2K | 1,503,853 | SEC↗ |
| JAFCO Super V3 Investment Limi | 10% Owner | S Sale | 2015-10-09 | 2015-10-13 | 1,448 | $10.01 | $14.5K | 1,505,573 | SEC↗ |
| JAFCO Super V3 Investment Limi | 10% Owner | S Sale | 2015-10-08 | 2015-10-08 | 9,632 | $10.11 | $97.4K | 1,507,021 | SEC↗ |
| JAFCO Super V3 Investment Limi | 10% Owner | S Sale | 2015-10-07 | 2015-10-08 | 12,288 | $10.09 | $124.0K | 1,516,653 | SEC↗ |
| SHAZER RONALD L | Chief Medical Officer | A Award deriv | 2015-10-05 | 2015-10-06 | 153,139 | — | $0 | 153,139 | SEC↗ |
| JAFCO Super V3 Investment Limi | 10% Owner | S Sale | 2015-10-05 | 2015-10-06 | 8,800 | $10.10 | $88.9K | 1,528,941 | SEC↗ |
| JAFCO Super V3 Investment Limi | 10% Owner | S Sale | 2015-10-02 | 2015-10-06 | 6,300 | $10.06 | $63.4K | 1,537,741 | SEC↗ |
| JAFCO Super V3 Investment Limi | 10% Owner | S Sale | 2015-09-25 | 2015-09-29 | 7,600 | $12.13 | $92.2K | 1,544,041 | SEC↗ |