Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$0
Insiders on file
49
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Giffin Brett A. | Chief Commercial Officer | 18 | $5.2K | $3.0K | 2024-11-04 |
| Adams Laura Lee | Director | 8 | $0 | $0 | 2024-11-04 |
| Toft Robin | Director | 18 | $0 | $0 | 2024-11-04 |
| Saunders Ninfa | Director | 20 | $0 | $0 | 2024-11-04 |
| Sprague John M | Chief Financial Officer | 41 | $4.8K | $15.8K | 2024-11-04 |
| Gibbs Michael Terrence | General Counsel | 75 | $8.4K | $70.2K | 2024-11-04 |
| Sperzel John J III | See Remarks | 19 | $15.0K | $6.2K | 2024-11-04 |
| Elsbree David B | Director | 50 | $543.6K | $11.5K | 2024-11-04 |
| LIEBMAN SEYMOUR | Director | 31 | $0 | $0 | 2024-11-04 |
| CUMMING JOHN W | Director | 21 | $0 | $26.0K | 2024-11-04 |
| CRG Partners III L.P. | 10% Owner | 8 | $0 | $1.32M | 2024-05-09 |
| CRG Partners III - Parallel Fund (A) L.P. | 10% Owner | 13 | $0 | $0 | 2024-05-03 |
| CRG Partners III (Cayman) Unlev AIV I L.P. | 10% Owner | 14 | $0 | $4.93M | 2024-04-12 |
| CRG Partners III (Cayman) Lev AIV I L.P. | 10% Owner | 12 | $0 | $2.34M | 2023-09-28 |
| CR Group L.P. | 10% Owner | 10 | $0 | $4.31M | 2023-09-21 |
| Bernard Thierry | Director | 19 | $0 | $0 | 2023-09-15 |
| Barclay Alec | See Remarks | 36 | $6.5K | $55.3K | 2022-04-08 |
| Ahuja Aparna | Chief Medical Officer | 5 | $0 | $29.8K | 2022-02-20 |
| McDonough John | President and CEO | 43 | $0 | $211.4K | 2021-07-01 |
| Pare Anthony | Chief Commercial Officer | 6 | $0 | $17.7K | 2021-03-17 |
| GOLDMAN SACHS & CO. LLC | 10% Owner | 32 | $29.7K | $25.6K | 2020-05-20 |
| Jones Adrian M | Director | 37 | $29.7K | $25.6K | 2020-05-20 |
| Lowery Thomas J. | Chief Scientific Officer | 80 | $0 | $1.35M | 2020-03-14 |
| GOLDMAN SACHS GROUP INC | 10% Owner | 4 | $0 | $0 | 2020-01-02 |
| Lapidus Stanley | Director | 15 | $0 | $98.2K | 2019-06-11 |
| Cima Michael J. | Director | 18 | $54.9K | $4.6K | 2019-06-11 |
| Spadoro Joanne | Chief Operations Officer | 4 | $17.5K | $0 | 2017-06-06 |
| Dhanda Rahul | SVP of Corporate Development | 21 | $3.5K | $228.0K | 2017-06-06 |
| DEPTULA-HICKS DARLENE M | SVP & Chief Financial Officer | 2 | $14.3K | $0 | 2017-06-06 |
| Lynch Shawn | Chief Financial Officer | 3 | $0 | $0 | 2017-02-09 |
| Harding David | Chief Commercial Officer | 3 | $0 | $0 | 2017-02-09 |
| Bilenker Joshua H. | Director | 2 | $0 | $0 | 2016-06-17 |
| WILCOX HARRY W | Director | 2 | $0 | $0 | 2016-06-17 |
| Kalil Sarah O. | Chief Operating Officer | 6 | $220.0K | $0 | 2016-01-20 |
| Pfaller Michael A. | Chief Medical Officer | 4 | $0 | $251.8K | 2016-01-20 |
| MBD Advisors, L.L.C. | 10% Owner | 4 | $16.82M | $0 | 2015-12-09 |
| MBD 2013, L.P. | 10% Owner | 1 | $6.83M | $0 | 2015-12-09 |
| Aisling Capital Partners III LLC | 10% Owner | 1 | $3.00M | $0 | 2015-12-09 |
| CARELLA THOMAS J. | Director | 5 | $16.82M | $0 | 2015-12-09 |
| CASTONGUAY MAURICE L | Chief Financial Officer | 1 | $0 | $0 | 2015-08-06 |
| Polaris Venture Partners Founders' Fund V, L.P. | 10% Owner | 36 | $0 | $2.15M | 2015-08-05 |
| Polaris Venture Partners V, L.P. | 10% Owner | 28 | $0 | $1.43M | 2015-07-24 |
| Polaris Venture Management Co. V, L.L.C. | 10% Owner | 34 | $0 | $1.46M | 2015-07-10 |
| Polaris Venture Partners Entrepreneurs' Fund V, L.P. | 10% Owner | 12 | $0 | $768.2K | 2015-06-26 |
| LAPIDUS STANLEY N | Director | 1 | $0 | $0 | 2015-06-19 |
| Bridge Street 2013, L.P. | 10% Owner | 3 | $10.00M | $0 | 2014-08-12 |
| Flagship Ventures General Partner LLC | 10% Owner | 8 | $0 | $0 | 2014-08-12 |
| Crane Alan L | Director | 1 | $330.0K | $0 | 2014-08-12 |
| SCHIFF ANDREW N | 10% Owner | 4 | $5.00M | $0 | 2014-08-12 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Sprague John M | CFO | A Award deriv | 2024-11-04 | 2025-01-02 | 180,000 | — | $0 | 180,000 | SEC↗ |
| Sprague John M | CFO | A Award deriv | 2024-11-04 | 2025-01-02 | 180,000 | — | $0 | 180,000 | SEC↗ |
| Elsbree David B | Director | A Award deriv | 2024-11-04 | 2025-01-02 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Sperzel John J III | See Remarks | A Award deriv | 2024-11-04 | 2025-01-02 | 490,000 | — | $0 | 490,000 | SEC↗ |
| Sperzel John J III | See Remarks | A Award deriv | 2024-11-04 | 2025-01-02 | 490,000 | — | $0 | 490,000 | SEC↗ |
| Toft Robin | Director | A Award deriv | 2024-11-04 | 2025-01-02 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Saunders Ninfa | Director | A Award deriv | 2024-11-04 | 2025-01-02 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | A Award deriv | 2024-11-04 | 2025-01-02 | 190,000 | — | $0 | 190,000 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | A Award deriv | 2024-11-04 | 2025-01-02 | 190,000 | — | $0 | 190,000 | SEC↗ |
| CUMMING JOHN W | Director | A Award deriv | 2024-11-04 | 2025-01-02 | 35,000 | — | $0 | 35,000 | SEC↗ |
| Adams Laura Lee | Director | A Award deriv | 2024-11-04 | 2025-01-02 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | A Award deriv | 2024-11-04 | 2025-01-02 | 180,000 | — | $0 | 180,000 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | A Award deriv | 2024-11-04 | 2025-01-02 | 180,000 | — | $0 | 180,000 | SEC↗ |
| LIEBMAN SEYMOUR | Director | A Award deriv | 2024-11-04 | 2025-01-02 | 25,000 | — | $0 | 25,000 | SEC↗ |
| Elsbree David B | Director | S Sale | 2024-09-13 | 2024-09-17 | 55 | $2.42 | $133 | 23 | SEC↗ |
| CRG Partners III L.P. | 10% Owner | C Conversion deriv | 2024-05-09 | 2024-05-13 | 10,875 | — | $0 | 0 | SEC↗ |
| CRG Partners III L.P. | 10% Owner | C Conversion deriv | 2024-05-09 | 2024-05-13 | 17,160 | — | $0 | 0 | SEC↗ |
| CRG Partners III L.P. | 10% Owner | C Conversion | 2024-05-09 | 2024-05-13 | 108,752 | — | $0 | 4,704,729 | SEC↗ |
| CRG Partners III L.P. | 10% Owner | C Conversion | 2024-05-09 | 2024-05-13 | 1,716,048 | — | $0 | 4,595,977 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | A Award | 2024-05-03 | 2024-05-07 | 129,629 | — | $0 | 266,038 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | A Award | 2024-05-03 | 2024-05-07 | 648,139 | — | $0 | 1,330,175 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | A Award | 2024-05-03 | 2024-05-07 | 2,001,514 | — | $0 | 2,879,929 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | A Award | 2024-05-03 | 2024-05-07 | 1,565,445 | — | $0 | 3,548,707 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | A Award | 2024-05-03 | 2024-05-07 | 403,608 | — | $0 | 828,324 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | A Award deriv | 2024-04-12 | 2024-04-16 | 17,160 | — | $0 | 28,036 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | A Award | 2024-04-12 | 2024-04-16 | 424,716 | — | $0 | 424,716 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | A Award | 2024-04-12 | 2024-04-16 | 1,647,315 | — | $0 | 1,983,262 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | A Award | 2024-04-12 | 2024-04-16 | 682,036 | — | $0 | 682,036 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | A Award | 2024-04-12 | 2024-04-16 | 390,142 | — | $0 | 878,415 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | A Award | 2024-04-12 | 2024-04-16 | 136,409 | — | $0 | 136,409 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise deriv | 2024-02-24 | 2024-02-27 | 29 | — | $0 | 0 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2024-02-24 | 2024-02-27 | 29 | — | $0 | 0 | SEC↗ |
| Sperzel John J III | See Remarks | M Exercise deriv | 2024-02-24 | 2024-02-27 | 67 | — | $0 | 0 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise | 2024-02-24 | 2024-02-27 | 29 | — | $0 | 141 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2024-02-24 | 2024-02-27 | 29 | — | $0 | 135 | SEC↗ |
| Sperzel John J III | See Remarks | M Exercise | 2024-02-24 | 2024-02-27 | 67 | — | $0 | 400 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | A Award deriv | 2024-02-20 | 2024-02-20 | 13 | — | $0 | 13 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2024-02-20 | 2024-02-20 | 40 | — | $0 | 40 | SEC↗ |
| Sprague John M | Chief Financial Officer | A Award deriv | 2024-02-20 | 2024-02-20 | 40 | — | $0 | 40 | SEC↗ |
| Sperzel John J III | See Remarks | M Exercise deriv | 2024-02-20 | 2024-02-20 | 160 | — | $0 | 160 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | M Exercise | 2024-02-20 | 2024-02-20 | 13 | — | $0 | 77 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2024-02-20 | 2024-02-20 | 40 | — | $0 | 106 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise | 2024-02-20 | 2024-02-20 | 40 | — | $0 | 112 | SEC↗ |
| Sperzel John J III | See Remarks | M Exercise | 2024-02-20 | 2024-02-20 | 160 | — | $0 | 333 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | C Conversion deriv | 2024-02-14 | 2024-02-16 | 33,595 | — | $0 | 0 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | C Conversion deriv | 2024-02-14 | 2024-02-16 | 48,827 | — | $0 | 10,875 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | C Conversion | 2024-02-14 | 2024-02-16 | 488,273 | — | $0 | 488,273 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | C Conversion | 2024-02-14 | 2024-02-16 | 335,947 | — | $0 | 335,947 | SEC↗ |
| Toft Robin | Director | A Award deriv | 2024-01-01 | 2024-01-03 | 6,369 | — | $0 | 6,369 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | M Exercise deriv | 2023-11-08 | 2023-11-28 | 33 | — | $0 | 34 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | M Exercise | 2023-11-08 | 2023-11-28 | 33 | — | $0 | 64 | SEC↗ |
| Adams Laura Lee | Director | M Exercise deriv | 2023-10-18 | 2023-10-20 | 7 | — | $0 | 7 | SEC↗ |
| Adams Laura Lee | Director | M Exercise | 2023-10-18 | 2023-10-20 | 7 | — | $0 | 37 | SEC↗ |
| CRG Partners III (Cayman) Lev | 10% Owner | S Sale | 2023-09-28 | 2023-09-29 | 571,796 | $0.16 | $91.5K | 0 | SEC↗ |
| CRG Partners III (Cayman) Lev | 10% Owner | S Sale | 2023-09-28 | 2023-09-29 | 2,858,980 | $0.16 | $457.4K | 0 | SEC↗ |
| CRG Partners III (Cayman) Lev | 10% Owner | S Sale | 2023-09-28 | 2023-09-29 | 1,780,317 | $0.16 | $284.9K | 0 | SEC↗ |
| CRG Partners III (Cayman) Lev | 10% Owner | S Sale | 2023-09-28 | 2023-09-29 | 1,937,852 | $0.16 | $310.1K | 0 | SEC↗ |
| CRG Partners III (Cayman) Lev | 10% Owner | S Sale | 2023-09-27 | 2023-09-29 | 2,391,981 | $0.19 | $454.5K | 2,858,980 | SEC↗ |
| CRG Partners III (Cayman) Lev | 10% Owner | S Sale | 2023-09-27 | 2023-09-29 | 1,489,512 | $0.19 | $283.0K | 1,780,317 | SEC↗ |
| CRG Partners III (Cayman) Lev | 10% Owner | S Sale | 2023-09-27 | 2023-09-29 | 478,396 | $0.19 | $90.9K | 571,796 | SEC↗ |
| CRG Partners III (Cayman) Lev | 10% Owner | S Sale | 2023-09-27 | 2023-09-29 | 1,621,313 | $0.19 | $308.0K | 1,937,852 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | S Sale | 2023-09-26 | 2023-09-28 | 1,343,011 | $0.20 | $268.6K | 3,269,829 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | S Sale | 2023-09-26 | 2023-09-28 | 2,156,717 | $0.20 | $431.3K | 5,250,961 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | S Sale | 2023-09-26 | 2023-09-28 | 431,343 | $0.20 | $86.3K | 1,050,192 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | S Sale | 2023-09-26 | 2023-09-28 | 1,461,849 | $0.20 | $292.4K | 3,559,165 | SEC↗ |
| CRG Partners III (Cayman) Lev | 10% Owner | S Sale | 2023-09-25 | 2023-09-27 | 67,767 | $0.25 | $16.9K | 5,021,014 | SEC↗ |
| CRG Partners III (Cayman) Lev | 10% Owner | S Sale | 2023-09-25 | 2023-09-27 | 99,979 | $0.25 | $25.0K | 7,407,678 | SEC↗ |
| CRG Partners III (Cayman) Lev | 10% Owner | S Sale | 2023-09-25 | 2023-09-27 | 62,258 | $0.25 | $15.6K | 4,612,840 | SEC↗ |
| CRG Partners III (Cayman) Lev | 10% Owner | S Sale | 2023-09-25 | 2023-09-27 | 19,996 | $0.25 | $5.0K | 1,481,535 | SEC↗ |
| CRG Partners III L.P. | 10% Owner | S Sale | 2023-09-22 | 2023-09-26 | 2,031,313 | $0.26 | $528.1K | 7,507,657 | SEC↗ |
| CRG Partners III L.P. | 10% Owner | S Sale | 2023-09-22 | 2023-09-26 | 406,263 | $0.26 | $105.6K | 1,501,531 | SEC↗ |
| CRG Partners III L.P. | 10% Owner | S Sale | 2023-09-22 | 2023-09-26 | 1,376,848 | $0.26 | $358.0K | 5,088,781 | SEC↗ |
| CRG Partners III L.P. | 10% Owner | S Sale | 2023-09-22 | 2023-09-26 | 1,264,920 | $0.26 | $328.9K | 4,675,098 | SEC↗ |
| CR Group L.P. | 10% Owner | S Sale | 2023-09-21 | 2023-09-25 | 2,534,754 | $0.30 | $760.4K | 9,538,970 | SEC↗ |
| CR Group L.P. | 10% Owner | S Sale | 2023-09-21 | 2023-09-25 | 1,578,419 | $0.30 | $473.5K | 5,940,018 | SEC↗ |
| CR Group L.P. | 10% Owner | S Sale | 2023-09-21 | 2023-09-25 | 1,718,087 | $0.30 | $515.4K | 6,465,629 | SEC↗ |
| CR Group L.P. | 10% Owner | S Sale | 2023-09-21 | 2023-09-25 | 506,951 | $0.30 | $152.1K | 1,907,794 | SEC↗ |
| CR Group L.P. | 10% Owner | S Sale | 2023-09-20 | 2023-09-22 | 3,100,836 | $0.31 | $961.3K | 12,073,724 | SEC↗ |
| CR Group L.P. | 10% Owner | S Sale | 2023-09-20 | 2023-09-22 | 1,930,923 | $0.31 | $598.6K | 7,518,437 | SEC↗ |
| CR Group L.P. | 10% Owner | S Sale | 2023-09-20 | 2023-09-22 | 2,101,784 | $0.31 | $651.6K | 8,183,716 | SEC↗ |
| CR Group L.P. | 10% Owner | S Sale | 2023-09-20 | 2023-09-22 | 620,167 | $0.31 | $192.3K | 2,414,745 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | S Sale | 2023-09-19 | 2023-09-21 | 4,159,717 | $0.37 | $1.54M | 15,174,560 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | S Sale | 2023-09-19 | 2023-09-21 | 831,943 | $0.37 | $307.8K | 3,034,912 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | S Sale | 2023-09-19 | 2023-09-21 | 2,819,506 | $0.37 | $1.04M | 10,285,500 | SEC↗ |
| CRG Partners III (Cayman) Unle | 10% Owner | S Sale | 2023-09-19 | 2023-09-21 | 2,590,300 | $0.37 | $958.4K | 9,449,360 | SEC↗ |
| Adams Laura Lee | Director | M Exercise deriv | 2023-09-15 | 2023-10-11 | 2,300 | — | $0 | 0 | SEC↗ |
| Saunders Ninfa | Director | M Exercise deriv | 2023-09-15 | 2023-10-11 | 2,300 | — | $0 | 0 | SEC↗ |
| LIEBMAN SEYMOUR | Director | M Exercise deriv | 2023-09-15 | 2023-10-11 | 2,300 | — | $0 | 0 | SEC↗ |
| Bernard Thierry | Director | M Exercise deriv | 2023-09-15 | 2023-10-11 | 2,300 | — | $0 | 0 | SEC↗ |
| Elsbree David B | Director | M Exercise deriv | 2023-09-15 | 2023-10-11 | 2,300 | — | $0 | 0 | SEC↗ |
| Toft Robin | Director | M Exercise deriv | 2023-09-15 | 2023-10-11 | 2,300 | — | $0 | 0 | SEC↗ |
| CUMMING JOHN W | Director | M Exercise deriv | 2023-09-15 | 2023-10-11 | 2,600 | — | $0 | 0 | SEC↗ |
| Adams Laura Lee | Director | M Exercise | 2023-09-15 | 2023-10-11 | 2,300 | — | $0 | 3,032 | SEC↗ |
| Saunders Ninfa | Director | M Exercise | 2023-09-15 | 2023-10-11 | 2,300 | — | $0 | 7,322 | SEC↗ |
| LIEBMAN SEYMOUR | Director | M Exercise | 2023-09-15 | 2023-10-11 | 2,300 | — | $0 | 7,002 | SEC↗ |
| Bernard Thierry | Director | M Exercise | 2023-09-15 | 2023-10-11 | 2,300 | — | $0 | 7,322 | SEC↗ |
| Elsbree David B | Director | M Exercise | 2023-09-15 | 2023-10-11 | 2,300 | — | $0 | 7,824 | SEC↗ |
| Toft Robin | Director | M Exercise | 2023-09-15 | 2023-10-11 | 2,300 | — | $0 | 5,772 | SEC↗ |
| CUMMING JOHN W | Director | M Exercise | 2023-09-15 | 2023-10-11 | 2,600 | — | $0 | 5,256 | SEC↗ |
| Toft Robin | Director | M Exercise deriv | 2023-08-06 | 2023-08-16 | 454 | — | $0 | 0 | SEC↗ |
| Saunders Ninfa | Director | M Exercise deriv | 2023-08-06 | 2023-08-16 | 454 | — | $0 | 0 | SEC↗ |
| Bernard Thierry | Director | M Exercise deriv | 2023-08-06 | 2023-08-16 | 454 | — | $0 | 0 | SEC↗ |
| Toft Robin | Director | M Exercise | 2023-08-06 | 2023-08-16 | 454 | — | $0 | 3,472 | SEC↗ |
| Saunders Ninfa | Director | M Exercise | 2023-08-06 | 2023-08-16 | 454 | — | $0 | 5,022 | SEC↗ |
| Bernard Thierry | Director | M Exercise | 2023-08-06 | 2023-08-16 | 454 | — | $0 | 5,022 | SEC↗ |
| CR Group L.P. | 10% Owner | A Award deriv | 2023-07-03 | 2023-07-14 | 33,595 | — | $0 | 33,595 | SEC↗ |
| CR Group L.P. | 10% Owner | A Award deriv | 2023-07-03 | 2023-07-14 | 59,703 | — | $0 | 59,703 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | A Award | 2023-07-03 | 2023-07-06 | 19,334,277 | — | $0 | 19,334,277 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | A Award | 2023-07-03 | 2023-07-06 | 12,039,660 | — | $0 | 12,039,660 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | A Award | 2023-07-03 | 2023-07-06 | 13,105,006 | — | $0 | 13,105,006 | SEC↗ |
| CRG Partners III - Parallel Fu | 10% Owner | A Award | 2023-07-03 | 2023-07-06 | 3,866,855 | — | $0 | 3,866,855 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | S Sale | 2023-03-28 | 2023-04-06 | 239 | $0.48 | $115 | 6,612 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2023-03-24 | 2023-04-05 | 334 | — | $0 | 0 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2023-03-24 | 2023-04-05 | 334 | — | $0 | 6,851 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2023-03-24 | 2023-03-28 | 333 | — | $0 | 0 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2023-03-24 | 2023-03-28 | 333 | — | $0 | 6,850 | SEC↗ |
| Sperzel John J III | Chairman and CEO | S Sale | 2023-02-28 | 2023-03-09 | 2,898 | $0.59 | $1.7K | 17,329 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | S Sale | 2023-02-28 | 2023-03-09 | 1,585 | $0.59 | $935 | 6,517 | SEC↗ |
| Sprague John M | Chief Financial Officer | S Sale | 2023-02-28 | 2023-03-09 | 1,148 | $0.59 | $677 | 7,268 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2023-02-24 | 2023-03-09 | 2,914 | — | $0 | 2,914 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise deriv | 2023-02-24 | 2023-03-09 | 2,914 | — | $0 | 2,914 | SEC↗ |
| Sperzel John J III | Chairman and CEO | M Exercise | 2023-02-24 | 2023-03-09 | 6,667 | — | $0 | 20,227 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2023-02-24 | 2023-03-09 | 2,914 | — | $0 | 8,102 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise | 2023-02-24 | 2023-03-09 | 2,914 | — | $0 | 8,416 | SEC↗ |
| Sperzel John J III | Chairman and CEO | S Sale | 2023-02-22 | 2023-03-09 | 6,875 | $0.65 | $4.5K | 13,560 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | S Sale | 2023-02-22 | 2023-03-09 | 2,145 | $0.65 | $1.4K | 5,188 | SEC↗ |
| Sprague John M | Chief Financial Officer | S Sale | 2023-02-22 | 2023-03-09 | 1,545 | $0.65 | $1.0K | 5,502 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | S Sale | 2023-02-22 | 2023-03-09 | 537 | $0.65 | $349 | 841 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | M Exercise deriv | 2023-02-20 | 2023-11-28 | 1,333 | — | $0 | 2,667 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | M Exercise | 2023-02-20 | 2023-11-28 | 1,333 | — | $0 | 3,586 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | S Sale | 2023-02-20 | 2023-11-28 | 537 | $0.65 | $349 | 3,049 | SEC↗ |
| Sperzel John J III | Chairman and CEO | M Exercise deriv | 2023-02-20 | 2023-03-09 | 6,667 | — | $0 | 6,667 | SEC↗ |
| Sperzel John J III | Chairman and CEO | M Exercise deriv | 2023-02-20 | 2023-03-09 | 16,000 | — | $0 | 32,000 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2023-02-20 | 2023-03-09 | 4,000 | — | $0 | 8,000 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise deriv | 2023-02-20 | 2023-03-09 | 4,000 | — | $0 | 8,000 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | M Exercise deriv | 2023-02-20 | 2023-03-09 | 1,333 | — | $0 | 2,667 | SEC↗ |
| Sperzel John J III | Chairman and CEO | M Exercise | 2023-02-20 | 2023-03-09 | 16,000 | — | $0 | 20,435 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2023-02-20 | 2023-03-09 | 4,000 | — | $0 | 7,333 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise | 2023-02-20 | 2023-03-09 | 4,000 | — | $0 | 7,047 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | M Exercise | 2023-02-20 | 2023-03-09 | 1,333 | — | $0 | 1,378 | SEC↗ |
| Saunders Ninfa | Director | M Exercise deriv | 2023-01-01 | 2023-08-16 | 1,550 | — | $0 | 0 | SEC↗ |
| Bernard Thierry | Director | M Exercise deriv | 2023-01-01 | 2023-08-16 | 1,550 | — | $0 | 0 | SEC↗ |
| Saunders Ninfa | Director | M Exercise | 2023-01-01 | 2023-08-16 | 1,550 | — | $0 | 4,568 | SEC↗ |
| Bernard Thierry | Director | M Exercise | 2023-01-01 | 2023-08-16 | 1,550 | — | $0 | 4,568 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | S Sale | 2022-11-10 | 2022-11-22 | 1,292 | $1.79 | $2.3K | 2,253 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | M Exercise deriv | 2022-11-08 | 2022-11-22 | 3,333 | — | $0 | 6,667 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | M Exercise | 2022-11-08 | 2022-11-22 | 3,333 | — | $0 | 3,545 | SEC↗ |
| Adams Laura Lee | Director | M Exercise deriv | 2022-10-18 | 2023-03-09 | 732 | — | $0 | 1,464 | SEC↗ |
| Adams Laura Lee | Director | M Exercise | 2022-10-18 | 2023-03-09 | 732 | — | $0 | 732 | SEC↗ |
| LIEBMAN SEYMOUR | Director | A Award deriv | 2022-10-11 | 2022-10-13 | 115,000 | — | $0 | 115,000 | SEC↗ |
| CUMMING JOHN W | Director | A Award deriv | 2022-10-11 | 2022-10-13 | 130,000 | — | $0 | 130,000 | SEC↗ |
| Adams Laura Lee | Director | A Award deriv | 2022-10-11 | 2022-10-13 | 115,000 | — | $0 | 115,000 | SEC↗ |
| Toft Robin | Director | A Award deriv | 2022-10-11 | 2022-10-13 | 115,000 | — | $0 | 115,000 | SEC↗ |
| Saunders Ninfa | Director | A Award deriv | 2022-10-11 | 2022-10-13 | 115,000 | — | $0 | 115,000 | SEC↗ |
| Elsbree David B | Director | A Award deriv | 2022-10-11 | 2022-10-13 | 115,000 | — | $0 | 115,000 | SEC↗ |
| Bernard Thierry | Director | A Award deriv | 2022-10-11 | 2022-10-13 | 115,000 | — | $0 | 115,000 | SEC↗ |
| Bernard Thierry | Director | M Exercise deriv | 2022-08-06 | 2022-08-09 | 22,727 | — | $0 | 22,727 | SEC↗ |
| Saunders Ninfa | Director | M Exercise deriv | 2022-08-06 | 2022-08-09 | 22,727 | — | $0 | 22,727 | SEC↗ |
| Toft Robin | Director | M Exercise deriv | 2022-08-06 | 2022-08-09 | 22,727 | — | $0 | 22,727 | SEC↗ |
| Bernard Thierry | Director | M Exercise | 2022-08-06 | 2022-08-09 | 22,727 | — | $0 | 150,936 | SEC↗ |
| Saunders Ninfa | Director | M Exercise | 2022-08-06 | 2022-08-09 | 22,727 | — | $0 | 150,936 | SEC↗ |
| Toft Robin | Director | M Exercise | 2022-08-06 | 2022-08-09 | 22,727 | — | $0 | 150,936 | SEC↗ |
| Saunders Ninfa | Director | M Exercise deriv | 2022-06-25 | 2022-06-28 | 73,224 | — | $0 | 0 | SEC↗ |
| CUMMING JOHN W | Director | M Exercise deriv | 2022-06-25 | 2022-06-28 | 81,967 | — | $0 | 0 | SEC↗ |
| Elsbree David B | Director | M Exercise deriv | 2022-06-25 | 2022-06-28 | 73,224 | — | $0 | 0 | SEC↗ |
| LIEBMAN SEYMOUR | Director | M Exercise deriv | 2022-06-25 | 2022-06-28 | 73,224 | — | $0 | 0 | SEC↗ |
| Toft Robin | Director | M Exercise deriv | 2022-06-25 | 2022-06-28 | 73,224 | — | $0 | 0 | SEC↗ |
| Bernard Thierry | Director | M Exercise deriv | 2022-06-25 | 2022-06-28 | 73,224 | — | $0 | 0 | SEC↗ |
| Saunders Ninfa | Director | M Exercise | 2022-06-25 | 2022-06-28 | 73,224 | — | $0 | 128,209 | SEC↗ |
| CUMMING JOHN W | Director | M Exercise | 2022-06-25 | 2022-06-28 | 81,967 | — | $0 | 132,819 | SEC↗ |
| Elsbree David B | Director | M Exercise | 2022-06-25 | 2022-06-28 | 73,224 | — | $0 | 276,205 | SEC↗ |
| LIEBMAN SEYMOUR | Director | M Exercise | 2022-06-25 | 2022-06-28 | 73,224 | — | $0 | 235,121 | SEC↗ |
| Toft Robin | Director | M Exercise | 2022-06-25 | 2022-06-28 | 73,224 | — | $0 | 128,209 | SEC↗ |
| Bernard Thierry | Director | M Exercise | 2022-06-25 | 2022-06-28 | 73,224 | — | $0 | 128,209 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | P Buy | 2022-04-08 | 2022-04-11 | 10,600 | $0.49 | $5.2K | 10,600 | SEC↗ |
| Sprague John M | Chief Financial Officer | P Buy | 2022-04-08 | 2022-04-11 | 10,000 | $0.48 | $4.8K | 152,350 | SEC↗ |
| Barclay Alec | Chief Operations Officer | P Buy | 2022-04-08 | 2022-04-11 | 12,952 | $0.50 | $6.5K | 181,945 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | P Buy | 2022-04-07 | 2022-04-11 | 10,000 | $0.49 | $4.9K | 166,651 | SEC↗ |
| Sperzel John J III | Chairman, CEO, and President | P Buy | 2022-04-07 | 2022-04-11 | 30,000 | $0.50 | $15.0K | 221,773 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2022-03-24 | 2022-03-28 | 16,666 | — | $0 | 16,667 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2022-03-24 | 2022-03-28 | 16,666 | — | $0 | 165,441 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | F Tax w/h | 2022-03-24 | 2022-03-28 | 8,790 | $0.44 | $3.9K | 156,651 | SEC↗ |
| Barclay Alec | Chief Operations Officer | M Exercise deriv | 2022-03-14 | 2022-03-30 | 21,666 | — | $0 | 21,667 | SEC↗ |
| Barclay Alec | Chief Operations Officer | F Tax w/h | 2022-03-14 | 2022-03-30 | 11,428 | $0.36 | $4.1K | 168,993 | SEC↗ |
| Barclay Alec | Chief Operations Officer | M Exercise | 2022-03-14 | 2022-03-30 | 21,666 | — | $0 | 180,421 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | A Award deriv | 2022-02-26 | 2022-03-30 | 500,000 | — | $0 | 500,000 | SEC↗ |
| Sperzel John J III | See Remarks | M Exercise deriv | 2022-02-24 | 2022-02-28 | 333,333 | — | $0 | 666,667 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2022-02-24 | 2022-02-28 | 145,719 | — | $0 | 291,439 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise deriv | 2022-02-24 | 2022-02-28 | 145,719 | — | $0 | 291,439 | SEC↗ |
| Barclay Alec | Chief Operations Officer | M Exercise deriv | 2022-02-24 | 2022-02-28 | 168,488 | — | $0 | 336,976 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2022-02-24 | 2022-03-28 | 145,719 | — | $0 | 291,439 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise deriv | 2022-02-24 | 2022-03-29 | 145,719 | — | $0 | 291,439 | SEC↗ |
| Sperzel John J III | See Remarks | F Tax w/h | 2022-02-24 | 2022-02-28 | 141,560 | $0.45 | $63.7K | 191,773 | SEC↗ |
| Sperzel John J III | See Remarks | M Exercise | 2022-02-24 | 2022-02-28 | 333,333 | — | $0 | 333,333 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | F Tax w/h | 2022-02-24 | 2022-02-28 | 76,867 | $0.45 | $34.6K | 138,775 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2022-02-24 | 2022-02-28 | 145,719 | — | $0 | 215,642 | SEC↗ |
| Sprague John M | Chief Financial Officer | F Tax w/h | 2022-02-24 | 2022-02-28 | 55,008 | $0.45 | $24.8K | 136,196 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise | 2022-02-24 | 2022-02-28 | 145,719 | — | $0 | 191,204 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | F Tax w/h | 2022-02-24 | 2022-03-28 | 76,867 | $0.45 | $34.6K | 148,775 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2022-02-24 | 2022-03-28 | 145,719 | — | $0 | 225,642 | SEC↗ |
| Sprague John M | Chief Financial Officer | F Tax w/h | 2022-02-24 | 2022-03-29 | 55,008 | $0.45 | $24.8K | 142,350 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise | 2022-02-24 | 2022-03-29 | 145,719 | — | $0 | 197,358 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2022-02-21 | 2022-02-23 | 10,000 | — | $0 | 0 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise deriv | 2022-02-21 | 2022-02-23 | 10,000 | — | $0 | 0 | SEC↗ |
| Barclay Alec | Chief Operations Officer | M Exercise deriv | 2022-02-21 | 2022-02-23 | 10,000 | — | $0 | 0 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2022-02-21 | 2022-03-28 | 10,000 | — | $0 | 0 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise deriv | 2022-02-21 | 2022-03-29 | 10,000 | — | $0 | 0 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | F Tax w/h | 2022-02-21 | 2022-02-23 | 5,275 | $0.47 | $2.5K | 69,923 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2022-02-21 | 2022-02-23 | 10,000 | — | $0 | 75,198 | SEC↗ |
| Sprague John M | Chief Financial Officer | F Tax w/h | 2022-02-21 | 2022-02-23 | 3,775 | $0.47 | $1.8K | 45,485 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise | 2022-02-21 | 2022-02-23 | 10,000 | — | $0 | 55,414 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | F Tax w/h | 2022-02-21 | 2022-03-28 | 5,275 | $0.47 | $2.5K | 79,923 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2022-02-21 | 2022-03-28 | 10,000 | — | $0 | 85,198 | SEC↗ |
| Sprague John M | Chief Financial Officer | F Tax w/h | 2022-02-21 | 2022-03-29 | 3,775 | $0.47 | $1.8K | 51,639 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise | 2022-02-21 | 2022-03-29 | 10,000 | — | $0 | 55,414 | SEC↗ |
| Ahuja Aparna | Chief Medical Officer | A Award deriv | 2022-02-20 | 2022-02-23 | 600,000 | — | $0 | 600,000 | SEC↗ |
| Sperzel John J III | See Remarks | A Award deriv | 2022-02-20 | 2022-02-23 | 2,400,000 | — | $0 | 2,400,000 | SEC↗ |
| Giffin Brett A. | Chief Commercial Officer | A Award deriv | 2022-02-20 | 2022-02-23 | 200,000 | — | $0 | 200,000 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | A Award deriv | 2022-02-20 | 2022-02-23 | 600,000 | — | $0 | 600,000 | SEC↗ |
| Sprague John M | Chief Financial Officer | A Award deriv | 2022-02-20 | 2022-02-23 | 600,000 | — | $0 | 600,000 | SEC↗ |
| Barclay Alec | Chief Operations Officer | A Award deriv | 2022-02-20 | 2022-02-23 | 600,000 | — | $0 | 600,000 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | A Award deriv | 2022-02-20 | 2022-03-28 | 600,000 | — | $0 | 600,000 | SEC↗ |
| Sprague John M | Chief Financial Officer | A Award deriv | 2022-02-20 | 2022-03-29 | 600,000 | — | $0 | 600,000 | SEC↗ |
| Ahuja Aparna | Chief Medical Officer | S Sale | 2022-01-06 | 2022-01-10 | 61,988 | $0.48 | $29.8K | 107,611 | SEC↗ |
| Ahuja Aparna | Chief Medical Officer | M Exercise deriv | 2022-01-05 | 2022-01-06 | 153,664 | — | $0 | 307,328 | SEC↗ |
| Ahuja Aparna | Chief Medical Officer | M Exercise | 2022-01-05 | 2022-01-06 | 153,664 | — | $0 | 169,599 | SEC↗ |
| Elsbree David B | Director | M Exercise deriv | 2022-01-01 | 2022-01-04 | 32,258 | — | $0 | 0 | SEC↗ |
| Bernard Thierry | Director | A Award deriv | 2022-01-01 | 2022-01-04 | 77,519 | — | $0 | 77,519 | SEC↗ |
| Bernard Thierry | Director | M Exercise deriv | 2022-01-01 | 2022-01-04 | 32,258 | — | $0 | 0 | SEC↗ |
| LIEBMAN SEYMOUR | Director | A Award deriv | 2022-01-01 | 2022-01-04 | 77,519 | — | $0 | 77,519 | SEC↗ |
| LIEBMAN SEYMOUR | Director | M Exercise deriv | 2022-01-01 | 2022-01-04 | 32,258 | — | $0 | 0 | SEC↗ |
| Saunders Ninfa | Director | A Award deriv | 2022-01-01 | 2022-01-04 | 77,519 | — | $0 | 77,519 | SEC↗ |
| Saunders Ninfa | Director | M Exercise deriv | 2022-01-01 | 2022-01-04 | 32,258 | — | $0 | 0 | SEC↗ |
| Toft Robin | Director | M Exercise deriv | 2022-01-01 | 2022-01-04 | 32,258 | — | $0 | 0 | SEC↗ |
| Elsbree David B | Director | M Exercise | 2022-01-01 | 2022-01-04 | 32,258 | — | $0 | 202,981 | SEC↗ |
| Bernard Thierry | Director | M Exercise | 2022-01-01 | 2022-01-04 | 32,258 | — | $0 | 54,985 | SEC↗ |
| LIEBMAN SEYMOUR | Director | M Exercise | 2022-01-01 | 2022-01-04 | 32,258 | — | $0 | 161,897 | SEC↗ |
| Saunders Ninfa | Director | M Exercise | 2022-01-01 | 2022-01-04 | 32,258 | — | $0 | 54,985 | SEC↗ |
| Toft Robin | Director | M Exercise | 2022-01-01 | 2022-01-04 | 32,258 | — | $0 | 54,985 | SEC↗ |
| Bernard Thierry | Director | M Exercise deriv | 2021-08-06 | 2021-08-09 | 22,727 | — | $0 | 45,454 | SEC↗ |
| Saunders Ninfa | Director | M Exercise deriv | 2021-08-06 | 2021-08-09 | 22,727 | — | $0 | 45,454 | SEC↗ |
| Toft Robin | Director | M Exercise deriv | 2021-08-06 | 2021-08-10 | 22,727 | — | $0 | 45,454 | SEC↗ |
| Bernard Thierry | Director | M Exercise | 2021-08-06 | 2021-08-09 | 22,727 | — | $0 | 22,727 | SEC↗ |
| Saunders Ninfa | Director | M Exercise | 2021-08-06 | 2021-08-09 | 22,727 | — | $0 | 22,727 | SEC↗ |
| Toft Robin | Director | M Exercise | 2021-08-06 | 2021-08-10 | 22,727 | — | $0 | 22,727 | SEC↗ |
| CUMMING JOHN W | Director | S Sale | 2021-07-01 | 2021-07-02 | 18,182 | $1.16 | $21.1K | 50,852 | SEC↗ |
| McDonough John | Director | S Sale | 2021-07-01 | 2021-07-02 | 18,182 | $1.16 | $21.1K | 516,386 | SEC↗ |
| Toft Robin | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 73,224 | — | $0 | 73,224 | SEC↗ |
| Elsbree David B | Director | M Exercise deriv | 2021-06-25 | 2021-06-29 | 45,454 | — | $0 | 45,454 | SEC↗ |
| Elsbree David B | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 73,224 | — | $0 | 73,224 | SEC↗ |
| McDonough John | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 81,967 | — | $0 | 81,967 | SEC↗ |
| McDonough John | Director | M Exercise deriv | 2021-06-25 | 2021-06-29 | 45,454 | — | $0 | 45,454 | SEC↗ |
| LIEBMAN SEYMOUR | Director | M Exercise deriv | 2021-06-25 | 2021-06-29 | 45,454 | — | $0 | 45,454 | SEC↗ |
| LIEBMAN SEYMOUR | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 73,224 | — | $0 | 73,224 | SEC↗ |
| Bernard Thierry | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 73,224 | — | $0 | 73,224 | SEC↗ |
| CUMMING JOHN W | Director | M Exercise deriv | 2021-06-25 | 2021-06-29 | 45,454 | — | $0 | 45,454 | SEC↗ |
| CUMMING JOHN W | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 81,967 | — | $0 | 81,967 | SEC↗ |
| Saunders Ninfa | Director | A Award deriv | 2021-06-25 | 2021-06-29 | 73,224 | — | $0 | 73,224 | SEC↗ |
| Elsbree David B | Director | M Exercise | 2021-06-25 | 2021-06-29 | 45,454 | — | $0 | 170,723 | SEC↗ |
| McDonough John | Director | M Exercise | 2021-06-25 | 2021-06-29 | 45,454 | — | $0 | 534,568 | SEC↗ |
| LIEBMAN SEYMOUR | Director | M Exercise | 2021-06-25 | 2021-06-29 | 45,454 | — | $0 | 129,639 | SEC↗ |
| CUMMING JOHN W | Director | M Exercise | 2021-06-25 | 2021-06-29 | 45,454 | — | $0 | 69,034 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | S Sale | 2021-03-25 | 2021-03-25 | 8,758 | $1.56 | $13.7K | 73,256 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2021-03-24 | 2021-03-25 | 16,667 | — | $0 | 33,333 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2021-03-24 | 2021-03-25 | 16,667 | — | $0 | 82,014 | SEC↗ |
| Pare Anthony | Chief Commercial Officer | S Sale | 2021-03-17 | 2021-03-18 | 9,620 | $1.84 | $17.7K | 31,612 | SEC↗ |
| Barclay Alec | Chief Operations Officer | S Sale | 2021-03-17 | 2021-03-18 | 12,494 | $1.86 | $23.2K | 74,420 | SEC↗ |
| Barclay Alec | Chief Operations Officer | M Exercise deriv | 2021-03-14 | 2021-03-16 | 21,667 | — | $0 | 43,333 | SEC↗ |
| Pare Anthony | Chief Commercial Officer | M Exercise deriv | 2021-03-14 | 2021-03-16 | 17,500 | — | $0 | 35,000 | SEC↗ |
| Barclay Alec | Chief Operations Officer | M Exercise | 2021-03-14 | 2021-03-16 | 21,667 | — | $0 | 86,914 | SEC↗ |
| Pare Anthony | Chief Commercial Officer | M Exercise | 2021-03-14 | 2021-03-16 | 17,500 | — | $0 | 41,232 | SEC↗ |
| Barclay Alec | Chief Operations Officer | F Tax w/h | 2021-02-24 | 2022-02-28 | 88,878 | $0.45 | $40.0K | 158,755 | SEC↗ |
| Barclay Alec | Chief Operations Officer | M Exercise | 2021-02-24 | 2022-02-28 | 168,488 | — | $0 | 247,633 | SEC↗ |
| Barclay Alec | Chief Operations Officer | A Award deriv | 2021-02-24 | 2021-02-26 | 505,464 | — | $0 | 505,464 | SEC↗ |
| Pare Anthony | Chief Commercial Officer | A Award deriv | 2021-02-24 | 2021-02-26 | 505,464 | — | $0 | 505,464 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | A Award deriv | 2021-02-24 | 2021-02-26 | 437,158 | — | $0 | 437,158 | SEC↗ |
| Sprague John M | Chief Financial Officer | A Award deriv | 2021-02-24 | 2021-02-26 | 437,158 | — | $0 | 437,158 | SEC↗ |
| Sperzel John J III | See Remarks | A Award deriv | 2021-02-24 | 2021-02-26 | 1,693,989 | — | $0 | 1,693,989 | SEC↗ |
| Sperzel John J III | President and CEO | A Award deriv | 2021-02-24 | 2021-03-19 | 1,000,000 | — | $0 | 1,000,000 | SEC↗ |
| Barclay Alec | Chief Operations Officer | S Sale | 2021-02-23 | 2021-02-23 | 7,280 | $2.06 | $15.0K | 65,247 | SEC↗ |
| Sprague John M | Chief Financial Officer | S Sale | 2021-02-23 | 2021-02-23 | 5,250 | $2.04 | $10.7K | 35,485 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | S Sale | 2021-02-23 | 2021-02-23 | 7,280 | $2.06 | $15.0K | 65,347 | SEC↗ |
| Barclay Alec | Chief Operations Officer | M Exercise | 2021-02-21 | 2022-02-23 | 10,000 | — | $0 | 84,420 | SEC↗ |
| Barclay Alec | Chief Operations Officer | F Tax w/h | 2021-02-21 | 2022-02-23 | 5,275 | $0.47 | $2.5K | 79,145 | SEC↗ |
| Barclay Alec | Chief Operations Officer | M Exercise deriv | 2021-02-21 | 2021-02-23 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise deriv | 2021-02-21 | 2021-02-23 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise deriv | 2021-02-21 | 2021-02-23 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Barclay Alec | Chief Operations Officer | M Exercise | 2021-02-21 | 2021-02-23 | 10,000 | — | $0 | 72,527 | SEC↗ |
| Sprague John M | Chief Financial Officer | M Exercise | 2021-02-21 | 2021-02-23 | 10,000 | — | $0 | 40,735 | SEC↗ |
| Gibbs Michael Terrence | General Counsel | M Exercise | 2021-02-21 | 2021-02-23 | 10,000 | — | $0 | 72,627 | SEC↗ |
| Ahuja Aparna | Chief Medical Officer | A Award deriv | 2021-01-05 | 2021-01-19 | 460,992 | — | $0 | 460,992 | SEC↗ |
| Saunders Ninfa | Director | A Award deriv | 2021-01-01 | 2021-01-05 | 32,258 | — | $0 | 32,258 | SEC↗ |
| Toft Robin | Director | A Award deriv | 2021-01-01 | 2021-01-05 | 32,258 | — | $0 | 32,258 | SEC↗ |
| Elsbree David B | Director | A Award deriv | 2021-01-01 | 2021-01-05 | 32,258 | — | $0 | 32,258 | SEC↗ |
| Elsbree David B | Director | M Exercise deriv | 2021-01-01 | 2021-01-05 | 34,188 | — | $0 | 34,188 | SEC↗ |
| LIEBMAN SEYMOUR | Director | A Award deriv | 2021-01-01 | 2021-01-05 | 32,258 | — | $0 | 32,258 | SEC↗ |
| LIEBMAN SEYMOUR | Director | M Exercise deriv | 2021-01-01 | 2021-01-05 | 34,188 | — | $0 | 34,188 | SEC↗ |
| Bernard Thierry | Director | A Award deriv | 2021-01-01 | 2021-01-05 | 32,258 | — | $0 | 32,258 | SEC↗ |
| Elsbree David B | Director | M Exercise | 2021-01-01 | 2021-01-05 | 34,188 | — | $0 | 125,269 | SEC↗ |
| LIEBMAN SEYMOUR | Director | M Exercise | 2021-01-01 | 2021-01-05 | 34,188 | — | $0 | 84,185 | SEC↗ |