TTPH

TETRAPHASE PHARMACEUTICALS INCCIK 1373707 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for TTPH PRO

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AI insights for TTPH

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
LA JOLLA PHARMACEUTICAL CO	10% Owner	2	$8.09M	$0	2020-07-28
Edwards Larry G.	See Remarks	18	$0	$0	2020-07-28
Watt Christopher	VP, Finance	15	$0	$0	2020-07-28
Armistice Capital Master Fund Ltd.	Director, 10% Owner	10	$0	$0	2020-07-28
Stahl Maria D	See Remarks	25	$0	$0	2020-07-28
Macdonald Guy	President and Chief Executive	96	$0	$8.28M	2020-07-28
GAGE L PATRICK	Director	22	$183.5K	$675.0K	2020-07-28
Freund John Gordon	Director, 10% Owner	43	$4.77M	$17.41M	2019-12-10
Chodakewitz Jeffrey	Director	6	$0	$0	2019-06-10
Wysenski Nancy	Director	6	$0	$0	2019-06-10
BOHLIN GAREN G	Director	7	$0	$0	2019-06-10
HENWOOD GERALDINE	Director	5	$0	$0	2019-06-10
Tsai Larry	Chief Medical Officer	7	$0	$0	2019-01-17
Dumas Jacques	Chief ScientificOfficer	19	$0	$310.6K	2019-01-17
Unninayar Kamalam	Chief Financial Officer	2	$0	$0	2018-01-17
Horn Patrick Taylor	Chief Medical Officer	21	$0	$1.75M	2017-06-13
THOMPSON JOHN CRAIG	Chief Operating Officer	21	$0	$3.96M	2015-09-08
Lubner David Charles	SVP and CFO	39	$0	$2.52M	2015-08-14
Giroir L. Patrick Jr.	Other	2	$0	$0	2015-06-10
FMR LLC	Other	13	$4.50M	$0	2015-03-05
Gullans Steven R. Ph.D.	Director, 10% Owner	6	$3.70M	$0	2014-06-12
Sutcliffe Joyce A.	Senior Vice President, Biology	7	$0	$463.7K	2014-03-20
Skyline Venture Management IV, LLC	10% Owner	2	$0	$0	2014-03-12
BARUCH THOMAS R	10% Owner	2	$0	$1.02M	2013-09-18
Sohail Faysal A.	10% Owner	4	$0	$495.1K	2013-09-17
Mediphase II LLC	10% Owner	28	$2.00M	$0	2013-03-25
Xiao Xiao-Yi	10% Owner	2	$0	$0	2013-03-25
Petrillo Enrico	10% Owner	3	$3.47M	$0	2013-03-25
CMEA Ventures VI Management, L.P.	10% Owner	18	$4.50M	$0	2013-03-25
Flagship Ventures 2007 General Partner LLC	10% Owner	11	$3.44M	$0	2013-03-25
Cole Douglas G.	Director	2	$0	$0	2013-03-25
Trias Joaquim	10% Owner	8	$0	$0	2013-03-25
KANEKO YASUNORI	10% Owner	9	$4.77M	$0	2013-03-25

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Stahl Maria D	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	6,156	—	$0	0	SEC↗
Stahl Maria D	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	1,382	—	$0	0	SEC↗
Stahl Maria D	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	934	—	$0	0	SEC↗
Stahl Maria D	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	640	—	$0	0	SEC↗
Stahl Maria D	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	1,800	—	$0	0	SEC↗
Stahl Maria D	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	675	—	$0	0	SEC↗
Stahl Maria D	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	335	—	$0	0	SEC↗
Stahl Maria D	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	2,850	—	$0	0	SEC↗
Edwards Larry G.	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	640	—	$0	0	SEC↗
Edwards Larry G.	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	2,025	—	$0	0	SEC↗
Edwards Larry G.	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	1,875	—	$0	0	SEC↗
Edwards Larry G.	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	7,500	—	$0	0	SEC↗
Edwards Larry G.	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	623	—	$0	0	SEC↗
Edwards Larry G.	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	1,374	—	$0	0	SEC↗
Edwards Larry G.	See Remarks	D To issuer deriv	2020-07-28	2020-07-29	6,595	—	$0	0	SEC↗
Watt Christopher	Senior Vice President, Finan	D To issuer deriv	2020-07-28	2020-07-29	55	—	$0	0	SEC↗
Watt Christopher	Senior Vice President, Finan	D To issuer deriv	2020-07-28	2020-07-29	467	—	$0	0	SEC↗
Watt Christopher	Senior Vice President, Finan	D To issuer deriv	2020-07-28	2020-07-29	389	—	$0	0	SEC↗
Watt Christopher	Senior Vice President, Finan	D To issuer deriv	2020-07-28	2020-07-29	1,044	—	$0	0	SEC↗
Watt Christopher	Senior Vice President, Finan	D To issuer deriv	2020-07-28	2020-07-29	3,515	—	$0	0	SEC↗
Armistice Capital Master Fund	Director, 10% Owner	J Other deriv	2020-07-28	2020-07-30	0	—	$0	0	SEC↗
Armistice Capital Master Fund	Director, 10% Owner	J Other deriv	2020-07-28	2020-07-30	2,063,334	—	$0	0	SEC↗
Armistice Capital Master Fund	Director, 10% Owner	J Other deriv	2020-07-28	2020-07-30	0	—	$0	0	SEC↗
Armistice Capital Master Fund	Director, 10% Owner	J Other deriv	2020-07-28	2020-07-30	2,130,493	—	$0	0	SEC↗
Armistice Capital Master Fund	Director, 10% Owner	J Other deriv	2020-07-28	2020-07-30	0	—	$0	0	SEC↗
Armistice Capital Master Fund	Director, 10% Owner	J Other deriv	2020-07-28	2020-07-30	0	—	$0	0	SEC↗
Armistice Capital Master Fund	Director, 10% Owner	J Other deriv	2020-07-28	2020-07-30	3,333,334	—	$0	0	SEC↗
Armistice Capital Master Fund	Director, 10% Owner	J Other deriv	2020-07-28	2020-07-30	1,430,493	—	$0	0	SEC↗
Stahl Maria D	See Remarks	U Tender	2020-07-28	2020-07-29	250	—	$0	0	SEC↗
GAGE L PATRICK	Director	U Tender	2020-07-28	2020-07-29	1,944	—	$0	0	SEC↗
GAGE L PATRICK	Director	U Tender	2020-07-28	2020-07-29	191	—	$0	0	SEC↗
Macdonald Guy	Director	U Tender	2020-07-28	2020-07-29	15,703	—	$0	0	SEC↗
Edwards Larry G.	See Remarks	U Tender	2020-07-28	2020-07-29	1,346	—	$0	0	SEC↗
Watt Christopher	Senior Vice President, Finan	U Tender	2020-07-28	2020-07-29	769	—	$0	0	SEC↗
LA JOLLA PHARMACEUTICAL CO	10% Owner	P Buy	2020-07-28	2020-07-29	3,737,360	$2.00	$7.47M	4,822,360	SEC↗
Armistice Capital Master Fund	Director, 10% Owner	J Other	2020-07-28	2020-07-30	1,419,507	—	$0	0	SEC↗
Armistice Capital Master Fund	Director, 10% Owner	J Other	2020-07-28	2020-07-30	0	—	$0	0	SEC↗
LA JOLLA PHARMACEUTICAL CO	10% Owner	P Buy	2020-06-19	2020-06-22	234,698	$2.62	$614.9K	1,085,000	SEC↗
Freund John Gordon	Director	S Sale	2019-12-10	2019-12-12	524	$2.19	$1.1K	0	SEC↗
Freund John Gordon	Director	S Sale	2019-12-10	2019-12-12	14,507	$2.19	$31.8K	0	SEC↗
Macdonald Guy	Director	S Sale	2019-12-06	2019-12-09	5,735	$2.25	$12.9K	250	SEC↗
Macdonald Guy	Director	S Sale	2019-12-05	2019-12-09	1,870	$2.34	$4.4K	5,985	SEC↗
Edwards Larry G.	President and CEO	A Award deriv	2019-08-01	2019-08-02	150,000	—	$0	150,000	SEC↗
Edwards Larry G.	President and CEO	A Award deriv	2019-08-01	2019-08-02	50,000	—	$0	50,000	SEC↗
Stahl Maria D	CBO and General Counsel	A Award deriv	2019-08-01	2019-08-02	57,000	—	$0	57,000	SEC↗
Stahl Maria D	CBO and General Counsel	A Award deriv	2019-08-01	2019-08-02	18,000	—	$0	18,000	SEC↗
BOHLIN GAREN G	Director	A Award deriv	2019-06-10	2019-06-11	16,500	—	$0	16,500	SEC↗
Chodakewitz Jeffrey	Director	A Award deriv	2019-06-10	2019-06-11	16,500	—	$0	16,500	SEC↗
Freund John Gordon	Director	A Award deriv	2019-06-10	2019-06-11	16,500	—	$0	16,500	SEC↗
GAGE L PATRICK	Director	A Award deriv	2019-06-10	2019-06-11	16,500	—	$0	16,500	SEC↗
HENWOOD GERALDINE	Director	A Award deriv	2019-06-10	2019-06-11	16,500	—	$0	16,500	SEC↗
Wysenski Nancy	Director	A Award deriv	2019-06-10	2019-06-11	16,500	—	$0	16,500	SEC↗
Edwards Larry G.	President and CEO	A Award	2019-05-14	2019-08-02	4,148	—	$0	54,937	SEC↗
Edwards Larry G.	President and CEO	A Award	2019-04-02	2019-08-02	13,913	—	$0	50,789	SEC↗
Stahl Maria D	CBO and General Counsel	A Award	2019-04-02	2019-08-02	13,913	—	$0	37,611	SEC↗
Dumas Jacques	Chief ScientificOfficer	A Award deriv	2019-01-17	2019-01-18	140,000	—	$0	140,000	SEC↗
Dumas Jacques	Chief ScientificOfficer	A Award deriv	2019-01-17	2019-01-18	40,000	—	$0	40,000	SEC↗
Edwards Larry G.	Chief Operating Officer	A Award deriv	2019-01-17	2019-01-18	150,000	—	$0	150,000	SEC↗
Edwards Larry G.	Chief Operating Officer	A Award deriv	2019-01-17	2019-01-18	45,000	—	$0	45,000	SEC↗
Macdonald Guy	President and Chief Executiv	A Award deriv	2019-01-17	2019-01-18	300,000	—	$0	300,000	SEC↗
Macdonald Guy	President and Chief Executiv	A Award deriv	2019-01-17	2019-01-18	100,000	—	$0	100,000	SEC↗
Stahl Maria D	SVP and General Counsel	A Award deriv	2019-01-17	2019-01-18	140,000	—	$0	140,000	SEC↗
Stahl Maria D	SVP and General Counsel	A Award deriv	2019-01-17	2019-01-18	40,000	—	$0	40,000	SEC↗
Tsai Larry	Chief Medical Officer	A Award deriv	2019-01-17	2019-01-18	40,000	—	$0	40,000	SEC↗
Tsai Larry	Chief Medical Officer	A Award deriv	2019-01-17	2019-01-18	140,000	—	$0	140,000	SEC↗
Watt Christopher	SVP, Finance	A Award deriv	2019-01-17	2019-01-18	80,000	—	$0	80,000	SEC↗
Dumas Jacques	Chief ScientificOfficer	S Sale	2019-01-08	2019-01-10	7,497	$1.60	$12.0K	0	SEC↗
Edwards Larry G.	Chief Operating Officer	A Award	2019-01-06	2019-01-18	4,277	—	$0	32,309	SEC↗
Stahl Maria D	SVP and General Counsel	A Award	2019-01-06	2019-01-18	18,698	—	$0	23,698	SEC↗
Tsai Larry	Chief Medical Officer	A Award	2019-01-06	2019-01-18	3,337	—	$0	31,503	SEC↗
Watt Christopher	SVP, Finance	A Award	2019-01-06	2019-01-18	2,668	—	$0	21,782	SEC↗
Edwards Larry G.	Chief Operating Officer	A Award	2018-11-14	2019-01-18	2,509	—	$0	36,876	SEC↗
Macdonald Guy	President and Chief Executiv	A Award	2018-11-14	2019-01-18	3,332	—	$0	134,396	SEC↗
Watt Christopher	SVP, Finance	A Award	2018-11-14	2019-01-18	3,332	—	$0	27,172	SEC↗
BOHLIN GAREN G	Director	A Award deriv	2018-05-30	2018-06-01	12,500	—	$0	12,500	SEC↗
Chodakewitz Jeffrey	Director	A Award deriv	2018-05-30	2018-06-01	12,500	—	$0	12,500	SEC↗
Freund John Gordon	Director	A Award deriv	2018-05-30	2018-06-01	12,500	—	$0	12,500	SEC↗
GAGE L PATRICK	Director	A Award deriv	2018-05-30	2018-06-01	12,500	—	$0	12,500	SEC↗
HENWOOD GERALDINE	Director	A Award deriv	2018-05-30	2018-06-01	12,500	—	$0	12,500	SEC↗
Wysenski Nancy	Director	A Award deriv	2018-05-30	2018-06-01	12,500	—	$0	12,500	SEC↗
Edwards Larry G.	Chief Operating Officer	A Award	2018-05-14	2019-01-18	2,058	—	$0	34,367	SEC↗
Macdonald Guy	President and Chief Executiv	A Award	2018-05-14	2019-01-18	2,058	—	$0	131,064	SEC↗
Tsai Larry	Chief Medical Officer	A Award	2018-05-14	2019-01-18	2,058	—	$0	33,561	SEC↗
Watt Christopher	SVP, Finance	A Award	2018-05-14	2019-01-18	2,058	—	$0	23,840	SEC↗
Dumas Jacques	Chief ScientificOfficer	A Award deriv	2018-04-02	2018-04-04	40,000	—	$0	40,000	SEC↗
Edwards Larry G.	Chief Operating Officer	A Award deriv	2018-04-02	2018-04-04	40,000	—	$0	40,000	SEC↗
Macdonald Guy	President and Chief Executiv	A Award deriv	2018-04-02	2018-04-04	50,000	—	$0	50,000	SEC↗
Stahl Maria D	SVP and General Counsel	A Award deriv	2018-04-02	2018-04-04	40,000	—	$0	40,000	SEC↗
Tsai Larry	Chief Medical Officer	A Award deriv	2018-04-02	2018-04-04	40,000	—	$0	40,000	SEC↗
Watt Christopher	SVP, Finance	A Award deriv	2018-04-02	2018-04-04	30,000	—	$0	30,000	SEC↗
Dumas Jacques	Chief ScientificOfficer	M Exercise deriv	2018-01-30	2018-01-31	8,750	—	$0	105,000	SEC↗
Dumas Jacques	Chief ScientificOfficer	S Sale	2018-01-30	2018-01-31	8,750	$6.22	$54.4K	0	SEC↗
Dumas Jacques	Chief ScientificOfficer	M Exercise	2018-01-30	2018-01-31	8,750	$3.69	$32.3K	8,750	SEC↗
Macdonald Guy	President and Chief Executiv	A Award deriv	2018-01-19	2018-01-19	300,000	—	$0	300,000	SEC↗
Macdonald Guy	President and Chief Executiv	A Award deriv	2018-01-19	2018-01-19	100,000	—	$0	100,000	SEC↗
Dumas Jacques	Chief ScientificOfficer	A Award deriv	2018-01-17	2018-01-19	140,000	—	$0	140,000	SEC↗
Dumas Jacques	Chief ScientificOfficer	A Award deriv	2018-01-17	2018-01-19	40,000	—	$0	40,000	SEC↗
Stahl Maria D	SVP and General Counsel	A Award deriv	2018-01-17	2018-01-19	115,000	—	$0	115,000	SEC↗
Stahl Maria D	SVP and General Counsel	A Award deriv	2018-01-17	2018-01-19	32,000	—	$0	32,000	SEC↗
Tsai Larry	Chief Medical Officer	A Award deriv	2018-01-17	2018-01-19	40,000	—	$0	40,000	SEC↗
Tsai Larry	Chief Medical Officer	A Award deriv	2018-01-17	2018-01-19	150,000	—	$0	150,000	SEC↗
Unninayar Kamalam	Chief Financial Officer	A Award deriv	2018-01-17	2018-01-19	40,000	—	$0	40,000	SEC↗
Dumas Jacques	Chief ScientificOfficer	S Sale	2018-01-09	2018-01-11	7,167	$6.21	$44.5K	0	SEC↗
GAGE L PATRICK	Director	P Buy	2017-11-29	2017-12-04	3,880	$6.45	$25.0K	38,880	SEC↗
Unninayar Kamalam	Chief Financial Officer	A Award deriv	2017-11-15	2017-11-15	190,000	—	$0	190,000	SEC↗
Macdonald Guy	President and Chief Executiv	A Award	2017-11-14	2018-01-19	1,566	—	$0	129,006	SEC↗
Dumas Jacques	Chief ScientificOfficer	M Exercise deriv	2017-10-31	2017-11-02	8,750	—	$0	113,750	SEC↗
Dumas Jacques	Chief ScientificOfficer	M Exercise	2017-10-31	2017-11-02	8,750	$3.69	$32.3K	8,750	SEC↗
Dumas Jacques	Chief ScientificOfficer	S Sale	2017-10-31	2017-11-02	8,750	$6.03	$52.8K	0	SEC↗
Dumas Jacques	Chief ScientificOfficer	M Exercise deriv	2017-08-22	2017-08-24	17,500	—	$0	122,500	SEC↗
Dumas Jacques	Chief ScientificOfficer	M Exercise	2017-08-22	2017-08-24	17,500	$3.69	$64.6K	17,500	SEC↗
Dumas Jacques	Chief ScientificOfficer	S Sale	2017-08-22	2017-08-24	17,500	$6.00	$105.0K	0	SEC↗
Dumas Jacques	Chief ScientificOfficer	S Sale	2017-08-17	2017-08-21	7,155	$5.86	$41.9K	0	SEC↗
Horn Patrick Taylor	Chief Medical Officer	M Exercise deriv	2017-06-13	2017-06-14	10,000	—	$0	47,689	SEC↗
Horn Patrick Taylor	Chief Medical Officer	M Exercise	2017-06-13	2017-06-14	10,000	$2.03	$20.3K	10,000	SEC↗
BOHLIN GAREN G	Director	A Award deriv	2017-05-31	2017-06-01	12,500	—	$0	12,500	SEC↗
Chodakewitz Jeffrey	Director	A Award deriv	2017-05-31	2017-06-01	12,500	—	$0	12,500	SEC↗
Freund John Gordon	Director	A Award deriv	2017-05-31	2017-06-01	12,500	—	$0	12,500	SEC↗
GAGE L PATRICK	Director	A Award deriv	2017-05-31	2017-06-01	12,500	—	$0	12,500	SEC↗
HENWOOD GERALDINE	Director	A Award deriv	2017-05-31	2017-06-01	12,500	—	$0	12,500	SEC↗
Wysenski Nancy	Director	A Award deriv	2017-05-31	2017-06-01	12,500	—	$0	12,500	SEC↗
Macdonald Guy	President and Chief Executiv	A Award	2017-05-12	2018-01-19	3,101	—	$0	127,440	SEC↗
GAGE L PATRICK	Director	P Buy	2017-03-15	2017-03-16	1,000	$7.47	$7.5K	3,825	SEC↗
GAGE L PATRICK	Director	P Buy	2017-03-15	2017-03-16	10,000	$7.49	$74.9K	35,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2017-02-09	2017-02-13	30,378	—	$0	0	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2017-02-09	2017-02-13	30,378	$2.90	$88.1K	124,339	SEC↗
Dumas Jacques	Chief ScientificOfficer	A Award deriv	2017-01-31	2017-02-01	30,000	—	$0	30,000	SEC↗
Horn Patrick Taylor	Chief Medical Officer	A Award deriv	2017-01-31	2017-02-01	30,000	—	$0	30,000	SEC↗
Macdonald Guy	President and Chief Executiv	A Award deriv	2017-01-31	2017-02-01	300,000	—	$0	300,000	SEC↗
Macdonald Guy	President and Chief Executiv	A Award deriv	2017-01-31	2017-02-01	75,000	—	$0	75,000	SEC↗
Stahl Maria D	SVP and General Counsel	A Award deriv	2017-01-31	2017-02-01	25,000	—	$0	25,000	SEC↗
Watt Christopher	SVP, Finance	A Award deriv	2017-01-31	2017-02-01	15,000	—	$0	15,000	SEC↗
Dumas Jacques	Chief ScientificOfficer	A Award deriv	2017-01-30	2017-02-01	140,000	—	$0	140,000	SEC↗
Horn Patrick Taylor	Chief Medical Officer	A Award deriv	2017-01-30	2017-02-01	140,000	—	$0	140,000	SEC↗
Stahl Maria D	SVP and General Counsel	A Award deriv	2017-01-30	2017-02-01	115,000	—	$0	115,000	SEC↗
Watt Christopher	SVP, Finance	A Award deriv	2017-01-30	2017-02-01	60,000	—	$0	60,000	SEC↗
Macdonald Guy	President and Chief Executiv	A Award	2016-11-14	2017-02-01	3,204	—	$0	93,961	SEC↗
BOHLIN GAREN G	Director	A Award deriv	2016-06-08	2016-06-10	10,000	—	$0	10,000	SEC↗
Chodakewitz Jeffrey	Director	A Award deriv	2016-06-08	2016-06-10	10,000	—	$0	10,000	SEC↗
Freund John Gordon	Director	A Award deriv	2016-06-08	2016-06-10	10,000	—	$0	10,000	SEC↗
GAGE L PATRICK	Director	A Award deriv	2016-06-08	2016-06-10	10,000	—	$0	10,000	SEC↗
HENWOOD GERALDINE	Director	A Award deriv	2016-06-08	2016-06-10	10,000	—	$0	10,000	SEC↗
Wysenski Nancy	Director	A Award deriv	2016-06-08	2016-06-10	10,000	—	$0	10,000	SEC↗
Stahl Maria D	SVP and General Counsel	A Award	2016-05-17	2016-05-19	2,500	$3.75	$9.4K	5,000	SEC↗
Stahl Maria D	SVP and General Counsel	A Award	2016-05-17	2016-05-19	2,500	$3.89	$9.7K	2,500	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2016-05-16	2016-05-18	25,323	—	$0	20,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2016-05-16	2016-05-18	25,323	$0.87	$22.0K	90,757	SEC↗
Horn Patrick Taylor	Chief Medical Officer	A Award deriv	2016-01-06	2016-01-08	100,000	—	$0	100,000	SEC↗
Horn Patrick Taylor	Chief Medical Officer	A Award deriv	2016-01-06	2016-01-08	35,000	—	$0	35,000	SEC↗
Macdonald Guy	President and Chief Executiv	A Award deriv	2016-01-06	2016-01-08	300,000	—	$0	300,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2016-01-06	2016-01-08	12,000	—	$0	45,323	SEC↗
Stahl Maria D	SVP and General Counsel	A Award deriv	2016-01-06	2016-01-08	80,000	—	$0	80,000	SEC↗
Stahl Maria D	SVP and General Counsel	A Award deriv	2016-01-06	2016-01-08	30,000	—	$0	30,000	SEC↗
Watt Christopher	VP, Finance	A Award deriv	2016-01-06	2016-01-15	12,500	—	$0	12,500	SEC↗
Watt Christopher	VP, Finance	A Award deriv	2016-01-06	2016-01-15	25,000	—	$0	25,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2016-01-06	2016-01-08	12,000	$0.87	$10.4K	64,000	SEC↗
GAGE L PATRICK	Director	M Exercise deriv	2015-10-02	2015-10-06	20,000	—	$0	34,544	SEC↗
GAGE L PATRICK	Director	M Exercise	2015-10-02	2015-10-06	20,000	$2.03	$40.6K	25,000	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	M Exercise deriv	2015-09-08	2015-09-10	10,000	—	$0	157,501	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	M Exercise	2015-09-08	2015-09-10	10,000	$14.45	$144.5K	10,343	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	S Sale	2015-09-08	2015-09-10	10,000	$44.08	$440.8K	343	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-09-01	2015-09-03	10,000	—	$0	180,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-09-01	2015-09-03	10,000	$41.57	$415.7K	52,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-09-01	2015-09-03	10,000	$7.94	$79.4K	62,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-08-24	2015-08-25	12,000	—	$0	57,323	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-08-24	2015-08-25	12,000	$0.87	$10.4K	52,000	SEC↗
Lubner David Charles	SVP and CFO	M Exercise deriv	2015-08-14	2015-08-17	9,500	—	$0	123,799	SEC↗
Lubner David Charles	SVP and CFO	M Exercise	2015-08-14	2015-08-17	9,500	$7.94	$75.4K	78,770	SEC↗
Lubner David Charles	SVP and CFO	S Sale	2015-08-14	2015-08-17	9,500	$42.92	$407.7K	69,270	SEC↗
Horn Patrick Taylor	Chief Medical Officer	M Exercise deriv	2015-08-13	2015-08-17	10,000	—	$0	57,689	SEC↗
Horn Patrick Taylor	Chief Medical Officer	S Sale	2015-08-13	2015-08-17	10,000	$44.69	$446.9K	0	SEC↗
Horn Patrick Taylor	Chief Medical Officer	M Exercise	2015-08-13	2015-08-17	10,000	$2.03	$20.3K	10,000	SEC↗
GAGE L PATRICK	Director	M Exercise deriv	2015-08-12	2015-08-14	15,000	—	$0	5,000	SEC↗
GAGE L PATRICK	Director	M Exercise	2015-08-12	2015-08-14	15,000	$7.07	$106.0K	20,000	SEC↗
GAGE L PATRICK	Director	S Sale	2015-08-12	2015-08-14	15,000	$45.00	$675.0K	5,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-08-06	2015-08-07	30,000	$43.65	$1.31M	40,000	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	M Exercise deriv	2015-08-05	2015-08-07	10,000	—	$0	167,501	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	M Exercise	2015-08-05	2015-08-07	10,000	$14.45	$144.5K	10,343	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	S Sale	2015-08-05	2015-08-07	10,000	$46.31	$463.1K	343	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-08-03	2015-08-03	10,000	—	$0	190,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-08-03	2015-08-03	10,000	$7.94	$79.4K	80,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-08-03	2015-08-03	10,000	$47.45	$474.5K	70,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-07-20	2015-07-22	15,000	$50.72	$760.8K	70,000	SEC↗
Lubner David Charles	SVP and CFO	M Exercise deriv	2015-07-14	2015-07-15	1,701	—	$0	133,299	SEC↗
Lubner David Charles	SVP and CFO	M Exercise deriv	2015-07-14	2015-07-15	5,799	—	$0	13,744	SEC↗
Lubner David Charles	SVP and CFO	M Exercise	2015-07-14	2015-07-15	1,701	$7.94	$13.5K	76,770	SEC↗
Lubner David Charles	SVP and CFO	M Exercise	2015-07-14	2015-07-15	5,799	$2.03	$11.8K	75,069	SEC↗
Lubner David Charles	SVP and CFO	S Sale	2015-07-14	2015-07-15	7,500	$48.92	$366.9K	69,270	SEC↗
Horn Patrick Taylor	Chief Medical Officer	M Exercise deriv	2015-07-13	2015-07-15	10,000	—	$0	67,689	SEC↗
Horn Patrick Taylor	Chief Medical Officer	M Exercise	2015-07-13	2015-07-15	10,000	$2.03	$20.3K	10,000	SEC↗
Horn Patrick Taylor	Chief Medical Officer	S Sale	2015-07-13	2015-07-15	10,000	$48.93	$489.3K	0	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	M Exercise deriv	2015-07-06	2015-07-08	10,000	—	$0	177,501	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	M Exercise	2015-07-06	2015-07-08	10,000	$14.45	$144.5K	10,343	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	S Sale	2015-07-06	2015-07-08	10,000	$47.91	$479.1K	343	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-07-01	2015-07-02	10,000	—	$0	200,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-07-01	2015-07-02	10,000	$7.94	$79.4K	95,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-07-01	2015-07-02	10,000	$47.92	$479.2K	85,000	SEC↗
Lubner David Charles	SVP and CFO	M Exercise deriv	2015-06-15	2015-06-16	7,500	—	$0	19,543	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	M Exercise deriv	2015-06-15	2015-06-16	10,000	—	$0	187,501	SEC↗
Lubner David Charles	SVP and CFO	S Sale	2015-06-15	2015-06-16	7,500	$41.67	$312.5K	69,270	SEC↗
Lubner David Charles	SVP and CFO	M Exercise	2015-06-15	2015-06-16	7,500	$2.03	$15.2K	76,770	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	M Exercise	2015-06-15	2015-06-16	10,000	$14.45	$144.5K	10,343	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	S Sale	2015-06-15	2015-06-16	10,000	$41.51	$415.1K	343	SEC↗
Horn Patrick Taylor	Chief Medical Officer	M Exercise deriv	2015-06-12	2015-06-16	10,000	—	$0	77,689	SEC↗
Horn Patrick Taylor	Chief Medical Officer	M Exercise	2015-06-12	2015-06-16	10,000	$2.03	$20.3K	10,000	SEC↗
Horn Patrick Taylor	Chief Medical Officer	S Sale	2015-06-12	2015-06-16	10,000	$41.72	$417.2K	0	SEC↗
Lubner David Charles	SVP and CFO	S Sale	2015-06-12	2015-06-16	10,000	$41.29	$412.9K	69,270	SEC↗
BOHLIN GAREN G	Director	A Award deriv	2015-06-10	2015-06-11	10,000	—	$0	10,000	SEC↗
Wysenski Nancy	Director	A Award deriv	2015-06-10	2015-06-11	10,000	—	$0	10,000	SEC↗
Freund John Gordon	Director	A Award deriv	2015-06-10	2015-06-11	10,000	—	$0	10,000	SEC↗
Giroir L. Patrick Jr.	Director	A Award deriv	2015-06-10	2015-06-11	10,000	—	$0	10,000	SEC↗
GAGE L PATRICK	Director	A Award deriv	2015-06-10	2015-06-11	10,000	—	$0	10,000	SEC↗
Chodakewitz Jeffrey	Director	A Award deriv	2015-06-10	2015-06-11	10,000	—	$0	10,000	SEC↗
Giroir L. Patrick Jr.	Other	A Award deriv	2015-06-10	2015-06-12	0	—	$0	0	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	M Exercise deriv	2015-06-08	2015-06-10	22,499	—	$0	197,501	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	S Sale	2015-06-08	2015-06-10	11,862	$43.50	$516.0K	10,980	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	S Sale	2015-06-08	2015-06-10	10,637	$43.00	$457.4K	343	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	M Exercise	2015-06-08	2015-06-10	22,499	$14.45	$325.1K	22,842	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-06-01	2015-06-03	5,000	—	$0	84,323	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-06-01	2015-06-03	15,000	—	$0	69,323	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-06-01	2015-06-03	10,000	—	$0	210,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-06-01	2015-06-03	20,000	$0.87	$17.4K	90,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-06-01	2015-06-03	5,000	$41.92	$209.6K	85,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-06-01	2015-06-03	1,087	$41.98	$45.6K	70,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-06-01	2015-06-03	10,000	$7.94	$79.4K	81,087	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-06-01	2015-06-03	10,000	$41.86	$418.6K	71,087	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	M Exercise deriv	2015-05-15	2015-05-19	30,000	—	$0	220,000	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	M Exercise	2015-05-15	2015-05-19	30,000	$14.45	$433.5K	30,343	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	S Sale	2015-05-15	2015-05-19	30,000	$39.63	$1.19M	343	SEC↗
Lubner David Charles	SVP and CFO	M Exercise deriv	2015-05-14	2015-05-18	7,316	—	$0	27,043	SEC↗
Lubner David Charles	SVP and CFO	M Exercise deriv	2015-05-14	2015-05-18	7,684	—	$0	0	SEC↗
Lubner David Charles	SVP and CFO	M Exercise	2015-05-14	2015-05-18	7,684	$2.03	$15.6K	86,954	SEC↗
Lubner David Charles	SVP and CFO	S Sale	2015-05-14	2015-05-18	7,684	$39.28	$301.8K	79,270	SEC↗
Lubner David Charles	SVP and CFO	S Sale	2015-05-14	2015-05-18	7,316	$39.28	$287.4K	79,270	SEC↗
Lubner David Charles	SVP and CFO	M Exercise	2015-05-14	2015-05-18	7,316	$2.03	$14.9K	86,586	SEC↗
Horn Patrick Taylor	Chief Medical Officer	M Exercise deriv	2015-05-13	2015-05-15	10,000	—	$0	87,689	SEC↗
Horn Patrick Taylor	Chief Medical Officer	M Exercise	2015-05-13	2015-05-15	10,000	$2.03	$20.3K	10,000	SEC↗
Horn Patrick Taylor	Chief Medical Officer	S Sale	2015-05-13	2015-05-15	10,000	$39.88	$398.8K	0	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-05-11	2015-05-13	20,000	—	$0	220,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-05-11	2015-05-13	20,000	$41.51	$830.2K	70,537	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-05-11	2015-05-13	20,000	$7.94	$158.8K	90,537	SEC↗
Freund John Gordon	Director	J Other	2015-05-11	2015-05-13	4,493	—	$0	4,493	SEC↗
Freund John Gordon	Director	J Other	2015-05-11	2015-05-13	4,493	—	$0	0	SEC↗
Freund John Gordon	Director	J Other	2015-05-11	2015-05-13	3,006	—	$0	6,012	SEC↗
Freund John Gordon	Director	J Other	2015-05-11	2015-05-13	300,000	—	$0	590,146	SEC↗
HENWOOD GERALDINE	Director	A Award deriv	2015-04-15	2015-04-16	20,000	—	$0	20,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-03-26	2015-03-27	20,000	—	$0	89,323	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-03-26	2015-03-27	20,000	$0.87	$17.4K	70,537	SEC↗
FMR LLC	Other	G Gift	2015-03-05	2015-03-09	671,912	—	$0	0	SEC↗
Stahl Maria D	SVP and General Counsel	A Award deriv	2015-03-04	2015-03-05	125,000	—	$0	125,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-03-02	2015-03-04	10,000	—	$0	240,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-03-02	2015-03-04	200	$38.90	$7.8K	60,337	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-03-02	2015-03-04	10,000	$7.94	$79.4K	60,537	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-03-02	2015-03-04	9,800	$39.67	$388.8K	50,537	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-02-02	2015-02-04	10,000	—	$0	250,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-02-02	2015-02-04	10,000	$7.94	$79.4K	60,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-02-02	2015-02-04	7,600	$35.09	$266.7K	50,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-02-02	2015-02-04	2,400	$35.93	$86.2K	57,600	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-01-20	2015-01-22	1,256	—	$0	25,834	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-01-20	2015-01-22	22,030	—	$0	57,331	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-01-20	2015-01-22	849	—	$0	109,323	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2015-01-20	2015-01-22	10,000	—	$0	260,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-01-20	2015-01-22	10,000	$7.94	$79.4K	60,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2015-01-20	2015-01-22	34,135	$36.59	$1.25M	50,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-01-20	2015-01-22	849	$0.87	$739	60,849	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-01-20	2015-01-22	22,030	$2.03	$44.7K	82,879	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2015-01-20	2015-01-22	1,256	$5.80	$7.3K	84,135	SEC↗
Macdonald Guy	President and Chief Executiv	A Award deriv	2015-01-07	2015-01-09	200,000	—	$0	200,000	SEC↗
Lubner David Charles	SVP and CFO	A Award deriv	2015-01-07	2015-01-09	100,000	—	$0	100,000	SEC↗
THOMPSON JOHN CRAIG	Chief Operating Officer	A Award deriv	2015-01-07	2015-01-09	100,000	—	$0	100,000	SEC↗
Horn Patrick Taylor	Chief Medical Officer	A Award deriv	2015-01-07	2015-01-09	100,000	—	$0	100,000	SEC↗
Freund John Gordon	Director	S Sale	2014-10-02	2014-10-03	27,726	$20.72	$574.5K	968,008	SEC↗
Freund John Gordon	Director	S Sale	2014-10-02	2014-10-03	77,862	$21.02	$1.64M	890,146	SEC↗
Freund John Gordon	Director	S Sale	2014-10-01	2014-10-03	14,400	$20.41	$293.9K	1,123,480	SEC↗
Freund John Gordon	Director	S Sale	2014-10-01	2014-10-03	127,746	$20.89	$2.67M	995,734	SEC↗
Freund John Gordon	Director	S Sale	2014-09-30	2014-10-01	56,618	$20.17	$1.14M	1,137,880	SEC↗
Freund John Gordon	Director	S Sale	2014-09-29	2014-10-01	95,648	$20.19	$1.93M	1,194,498	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2014-09-23	2014-09-25	9,641	—	$0	79,361	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2014-09-23	2014-09-25	359	—	$0	12,534	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2014-09-23	2014-09-25	9,641	$2.03	$19.6K	59,641	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2014-09-23	2014-09-25	359	$2.03	$729	60,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2014-09-23	2014-09-25	10,000	$18.47	$184.7K	50,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2014-09-17	2014-09-18	10,000	—	$0	110,172	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2014-09-17	2014-09-18	10,000	$18.00	$180.0K	50,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2014-09-17	2014-09-18	10,000	$0.87	$8.7K	60,000	SEC↗
Freund John Gordon	Director	S Sale	2014-09-17	2014-09-18	77,000	$17.36	$1.34M	1,290,146	SEC↗
Freund John Gordon	Director	S Sale	2014-09-16	2014-09-18	67,356	$17.03	$1.15M	1,367,146	SEC↗
Freund John Gordon	Director	S Sale	2014-09-12	2014-09-15	53,544	$17.01	$910.8K	1,434,502	SEC↗
Freund John Gordon	Director	S Sale	2014-09-11	2014-09-15	2,100	$17.00	$35.7K	1,488,046	SEC↗
Freund John Gordon	Director	S Sale	2014-09-08	2014-09-09	4,473	$15.01	$67.1K	1,490,146	SEC↗
Freund John Gordon	Director	S Sale	2014-09-05	2014-09-09	12,227	$15.01	$183.5K	1,494,619	SEC↗
Freund John Gordon	Director	S Sale	2014-09-04	2014-09-05	41,200	$15.06	$620.5K	1,506,846	SEC↗
Freund John Gordon	Director	S Sale	2014-09-03	2014-09-05	142,100	$15.04	$2.14M	1,548,046	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2014-08-20	2014-08-22	10,000	—	$0	120,172	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2014-08-20	2014-08-22	10,000	$0.87	$8.7K	60,000	SEC↗
Macdonald Guy	President and Chief Executiv	S Sale	2014-08-20	2014-08-22	10,000	$11.59	$115.9K	50,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2014-08-05	2014-08-07	25,000	—	$0	130,172	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2014-08-05	2014-08-07	25,000	$0.87	$21.8K	50,000	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise deriv	2014-07-18	2014-07-22	40,000	—	$0	155,172	SEC↗
Macdonald Guy	President and Chief Executiv	M Exercise	2014-07-18	2014-07-22	40,000	$0.87	$34.8K	40,000	SEC↗