Open-mkt buys · 90d
—
0 trades · 0 insiders
Open-mkt sales · 90d
—
0 trades · 0 insiders
Net · 90d
$0
Insiders on file
25
Daily buy vs sell · 90 days
No data yet.
Insiders
| Insider | Role | Trades | Bought | Sold | Last trade |
|---|---|---|---|---|---|
| Bernstein Karen | Director | 4 | $0 | $0 | 2016-10-25 |
| Gregg Richard | Chief Scientific Officer | 25 | $0 | $0 | 2016-10-25 |
| Applebaum Scott | General Counsel | 2 | $0 | $0 | 2016-10-25 |
| Hatfield Jeffrey S. | Chief Executive Officer | 31 | $0 | $1.42M | 2016-10-25 |
| Sable Carole | Chief Medical Officer | 2 | $0 | $0 | 2016-10-25 |
| Fratamico Arthur | Chief Business Officer | 11 | $78.3K | $0 | 2016-10-25 |
| LEONARD JOHN M. | Director | 4 | $0 | $0 | 2016-10-25 |
| Morris Richard Steven | Chief Financial Officer | 10 | $0 | $0 | 2016-10-25 |
| Rowland Charles A Jr | Director | 6 | $0 | $0 | 2016-10-25 |
| Gunderson Robert V JR | Director | 14 | $0 | $0 | 2016-10-25 |
| SANTINI GINO | Director | 6 | $0 | $0 | 2016-10-25 |
| HAYDEN DONALD J JR | Director | 21 | $0 | $924.4K | 2016-10-25 |
| JUNIUS DANIEL M | Director | 2 | $0 | $0 | 2016-10-25 |
| Adage Capital Partners, L.P. | 10% Owner | 1 | $0 | $21.37M | 2016-09-14 |
| ROBERTS BRYAN E | Director, 10% Owner | 24 | $6.18M | $0 | 2016-05-26 |
| SANDELL SCOTT D | 10% Owner | 5 | $0 | $0 | 2015-07-01 |
| NEA PARTNERS 10 L P | 10% Owner | 3 | $0 | $0 | 2015-07-01 |
| BARRETT M JAMES | 10% Owner | 5 | $0 | $0 | 2015-07-01 |
| NEW ENTERPRISE ASSOCIATES 10 L P | 10% Owner | 1 | $0 | $0 | 2015-07-01 |
| BARRIS PETER J | 10% Owner | 14 | $6.51M | $0 | 2015-07-01 |
| NEWHALL CHARLES W III | Director | 4 | $0 | $0 | 2015-07-01 |
| SCHNELL DAVID | 10% Owner | 3 | $0 | $0 | 2015-03-24 |
| Barrett Peter | Director | 6 | $300.0K | $0 | 2014-09-29 |
| VENROCK MANAGEMENT III LLC | 10% Owner | 21 | $6.18M | $0 | 2014-09-29 |
| PROSPECT MANAGEMENT CO LLC | 10% Owner | 11 | $5.37M | $0 | 2014-09-29 |
Trade history
| Insider | Role | Code | Trade | Filed | Shares | Price | Value | Owned after | |
|---|---|---|---|---|---|---|---|---|---|
| Applebaum Scott | General Counsel | D To issuer deriv | 2016-10-25 | 2016-10-25 | 150,000 | $12.25 | $1.84M | 0 | SEC↗ |
| Morris Richard Steven | Chief Financial Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 15,000 | $6.60 | $99.0K | 0 | SEC↗ |
| Morris Richard Steven | Chief Financial Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 152,173 | $15.71 | $2.39M | 0 | SEC↗ |
| Morris Richard Steven | Chief Financial Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 15,000 | $12.72 | $190.8K | 0 | SEC↗ |
| Morris Richard Steven | Chief Financial Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 27,500 | $12.22 | $336.1K | 0 | SEC↗ |
| Morris Richard Steven | Chief Financial Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 27,500 | $12.42 | $341.6K | 0 | SEC↗ |
| SANTINI GINO | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 17,000 | $13.00 | $221.0K | 0 | SEC↗ |
| SANTINI GINO | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 10,000 | $8.57 | $85.7K | 0 | SEC↗ |
| SANTINI GINO | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 10,000 | $11.38 | $113.8K | 0 | SEC↗ |
| Fratamico Arthur | Chief Business Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 152,173 | $15.71 | $2.39M | 0 | SEC↗ |
| Fratamico Arthur | Chief Business Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 13,750 | $12.72 | $174.9K | 0 | SEC↗ |
| Fratamico Arthur | Chief Business Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 19,250 | $12.42 | $239.1K | 0 | SEC↗ |
| Fratamico Arthur | Chief Business Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 14,500 | $12.22 | $177.2K | 0 | SEC↗ |
| Fratamico Arthur | Chief Business Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 13,750 | $6.60 | $90.8K | 0 | SEC↗ |
| Bernstein Karen | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 20,000 | $9.99 | $199.8K | 0 | SEC↗ |
| Bernstein Karen | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 10,000 | $11.38 | $113.8K | 0 | SEC↗ |
| JUNIUS DANIEL M | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 20,000 | $9.63 | $192.6K | 0 | SEC↗ |
| HAYDEN DONALD J JR | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 10,000 | $11.38 | $113.8K | 0 | SEC↗ |
| HAYDEN DONALD J JR | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 10,000 | $8.57 | $85.7K | 0 | SEC↗ |
| HAYDEN DONALD J JR | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 17,000 | $13.00 | $221.0K | 0 | SEC↗ |
| HAYDEN DONALD J JR | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 18,182 | $15.71 | $285.6K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 26,086 | $17.55 | $457.8K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 60,000 | $12.22 | $733.2K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 60,000 | $12.42 | $745.2K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 50,000 | $12.72 | $636.0K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 50,000 | $6.60 | $330.0K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 134,782 | $13.87 | $1.87M | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 10,320 | $14.10 | $145.5K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 20,869 | $17.09 | $356.7K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 6,245 | $17.09 | $106.7K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 30,434 | $17.55 | $534.1K | 0 | SEC↗ |
| Sable Carole | Chief Medical Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 150,000 | $10.49 | $1.57M | 0 | SEC↗ |
| Gunderson Robert V JR | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 10,000 | $11.38 | $113.8K | 0 | SEC↗ |
| Gunderson Robert V JR | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 10,000 | $8.57 | $85.7K | 0 | SEC↗ |
| Gunderson Robert V JR | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 5,434 | $17.09 | $92.9K | 0 | SEC↗ |
| Gunderson Robert V JR | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 9,091 | $15.71 | $142.8K | 0 | SEC↗ |
| Gunderson Robert V JR | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 17,000 | $13.00 | $221.0K | 0 | SEC↗ |
| LEONARD JOHN M. | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 20,000 | $11.15 | $223.0K | 0 | SEC↗ |
| LEONARD JOHN M. | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 10,000 | $11.38 | $113.8K | 0 | SEC↗ |
| Rowland Charles A Jr | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 10,000 | $8.57 | $85.7K | 0 | SEC↗ |
| Rowland Charles A Jr | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 17,000 | $13.00 | $221.0K | 0 | SEC↗ |
| Rowland Charles A Jr | Director | D To issuer deriv | 2016-10-25 | 2016-10-25 | 10,000 | $11.38 | $113.8K | 0 | SEC↗ |
| Gregg Richard | Chief Science Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 21,647 | $17.09 | $369.9K | 0 | SEC↗ |
| Gregg Richard | Chief Science Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 14,306 | $6.60 | $94.4K | 0 | SEC↗ |
| Gregg Richard | Chief Science Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 21,250 | $12.72 | $270.3K | 0 | SEC↗ |
| Gregg Richard | Chief Science Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 32,750 | $12.42 | $406.8K | 0 | SEC↗ |
| Gregg Richard | Chief Science Officer | D To issuer deriv | 2016-10-25 | 2016-10-25 | 16,500 | $12.22 | $201.6K | 0 | SEC↗ |
| Morris Richard Steven | Chief Financial Officer | D To issuer | 2016-10-25 | 2016-10-25 | 828 | $21.00 | $17.4K | 0 | SEC↗ |
| Gregg Richard | Chief Science Officer | D To issuer | 2016-10-25 | 2016-10-25 | 228,274 | $21.00 | $4.79M | 228,274 | SEC↗ |
| Fratamico Arthur | Chief Business Officer | U Tender | 2016-10-24 | 2016-10-25 | 13,233 | $21.00 | $277.9K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | U Tender | 2016-10-24 | 2016-10-25 | 244,996 | $21.00 | $5.14M | 244,996 | SEC↗ |
| Gunderson Robert V JR | Director | U Tender | 2016-10-24 | 2016-10-25 | 15,830 | $21.00 | $332.4K | 0 | SEC↗ |
| Gunderson Robert V JR | Director | U Tender | 2016-10-24 | 2016-10-25 | 11,002 | $21.00 | $231.0K | 0 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise deriv | 2016-10-19 | 2016-10-21 | 87,301 | — | $0 | 0 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise deriv | 2016-10-19 | 2016-10-21 | 29,657 | — | $0 | 21,647 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise deriv | 2016-10-19 | 2016-10-21 | 6,944 | — | $0 | 14,306 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise | 2016-10-19 | 2016-10-21 | 6,944 | $14.40 | $100.0K | 228,274 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise | 2016-10-19 | 2016-10-21 | 87,301 | $3.91 | $341.3K | 191,673 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise | 2016-10-19 | 2016-10-21 | 29,657 | $7.13 | $211.5K | 221,330 | SEC↗ |
| Adage Capital Partners, L.P. | 10% Owner | S Sale | 2016-09-14 | 2016-09-16 | 1,025,000 | $20.85 | $21.37M | 2,375,000 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | S Sale | 2016-09-14 | 2016-09-16 | 50,000 | $20.81 | $1.04M | 244,996 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | A Award deriv | 2016-08-15 | 2016-08-17 | 60,000 | — | $0 | 60,000 | SEC↗ |
| Morris Richard Steven | Chief Financial Officer | A Award deriv | 2016-08-15 | 2016-08-17 | 27,500 | — | $0 | 27,500 | SEC↗ |
| Gregg Richard | Chief Science Officer | A Award deriv | 2016-08-15 | 2016-08-17 | 16,500 | — | $0 | 16,500 | SEC↗ |
| Fratamico Arthur | Chief Business Officer | A Award deriv | 2016-08-15 | 2016-08-17 | 14,500 | — | $0 | 14,500 | SEC↗ |
| Applebaum Scott | General Counsel | A Award deriv | 2016-08-10 | 2016-08-12 | 150,000 | — | $0 | 150,000 | SEC↗ |
| JUNIUS DANIEL M | Director | A Award deriv | 2016-07-27 | 2016-07-27 | 20,000 | — | $0 | 20,000 | SEC↗ |
| Sable Carole | Chief Medical Officer | A Award deriv | 2016-06-06 | 2016-06-08 | 150,000 | — | $0 | 150,000 | SEC↗ |
| LEONARD JOHN M. | Director | A Award deriv | 2016-05-26 | 2016-05-27 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Rowland Charles A Jr | Director | A Award deriv | 2016-05-26 | 2016-05-27 | 10,000 | — | $0 | 10,000 | SEC↗ |
| HAYDEN DONALD J JR | Director | A Award deriv | 2016-05-26 | 2016-05-27 | 10,000 | — | $0 | 10,000 | SEC↗ |
| ROBERTS BRYAN E | Director | A Award deriv | 2016-05-26 | 2016-05-27 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Bernstein Karen | Director | A Award deriv | 2016-05-26 | 2016-05-27 | 10,000 | — | $0 | 10,000 | SEC↗ |
| SANTINI GINO | Director | A Award deriv | 2016-05-26 | 2016-05-27 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Gunderson Robert V JR | Director | A Award deriv | 2016-05-26 | 2016-05-27 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | A Award | 2016-04-29 | 2016-08-17 | 747 | $6.11 | $4.6K | 294,996 | SEC↗ |
| Morris Richard Steven | Chief Financial Officer | A Award | 2016-04-29 | 2016-08-17 | 828 | $6.11 | $5.1K | 828 | SEC↗ |
| Gregg Richard | Chief Science Officer | A Award | 2016-04-29 | 2016-08-17 | 2,100 | $6.11 | $12.8K | 104,372 | SEC↗ |
| Fratamico Arthur | Chief Business Officer | A Award | 2016-04-29 | 2016-08-17 | 2,086 | $6.11 | $12.7K | 12,086 | SEC↗ |
| HAYDEN DONALD J JR | Director | M Exercise deriv | 2016-03-21 | 2016-03-21 | 1,935 | — | $0 | 0 | SEC↗ |
| HAYDEN DONALD J JR | Director | M Exercise deriv | 2016-03-21 | 2016-03-21 | 14,195 | — | $0 | 0 | SEC↗ |
| HAYDEN DONALD J JR | Director | M Exercise | 2016-03-21 | 2016-03-21 | 1,935 | $3.45 | $6.7K | 1,935 | SEC↗ |
| HAYDEN DONALD J JR | Director | M Exercise | 2016-03-21 | 2016-03-21 | 14,195 | $3.45 | $49.0K | 14,195 | SEC↗ |
| HAYDEN DONALD J JR | Director | S Sale | 2016-03-21 | 2016-03-21 | 16,130 | $7.42 | $119.7K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | A Award deriv | 2016-02-15 | 2016-02-16 | 60,000 | — | $0 | 60,000 | SEC↗ |
| Fratamico Arthur | Chief Business Officer | A Award deriv | 2016-02-15 | 2016-02-16 | 19,250 | — | $0 | 19,250 | SEC↗ |
| Morris Richard Steven | Chief Financial Officer | A Award deriv | 2016-02-15 | 2016-02-16 | 27,500 | — | $0 | 27,500 | SEC↗ |
| Gregg Richard | Chief Scientific Officer | A Award deriv | 2016-02-15 | 2016-02-16 | 32,750 | — | $0 | 32,750 | SEC↗ |
| HAYDEN DONALD J JR | Director | M Exercise deriv | 2015-12-29 | 2015-12-30 | 16,130 | — | $0 | 1,935 | SEC↗ |
| HAYDEN DONALD J JR | Director | M Exercise | 2015-12-29 | 2015-12-30 | 16,130 | $3.45 | $55.6K | 16,130 | SEC↗ |
| HAYDEN DONALD J JR | Director | S Sale | 2015-12-29 | 2015-12-30 | 16,130 | $18.00 | $290.3K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise | 2015-12-28 | 2016-01-25 | 26,537 | $3.45 | $91.6K | 294,249 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise deriv | 2015-12-28 | 2015-12-28 | 26,537 | — | $0 | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise | 2015-12-28 | 2015-12-28 | 26,537 | $3.45 | $91.6K | 293,897 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise deriv | 2015-12-23 | 2015-12-28 | 16,940 | — | $0 | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise deriv | 2015-12-23 | 2015-12-28 | 5,584 | — | $0 | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise | 2015-12-23 | 2015-12-28 | 5,584 | $3.45 | $19.3K | 272,944 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise | 2015-12-23 | 2015-12-28 | 16,940 | $3.45 | $58.4K | 289,884 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | S Sale | 2015-12-23 | 2015-12-28 | 22,524 | $17.00 | $382.9K | 267,360 | SEC↗ |
| Gregg Richard | Chief Scientific Officer | M Exercise | 2015-11-16 | 2016-01-25 | 15,000 | $3.91 | $58.6K | 102,272 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise deriv | 2015-11-16 | 2015-11-17 | 15,000 | — | $0 | 87,301 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise | 2015-11-16 | 2015-11-17 | 15,000 | $3.91 | $58.6K | 100,557 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise deriv | 2015-11-13 | 2015-11-17 | 6,773 | — | $0 | 0 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise deriv | 2015-11-13 | 2015-11-17 | 13,695 | — | $0 | 0 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise deriv | 2015-11-13 | 2015-11-17 | 65,089 | — | $0 | 102,301 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise | 2015-11-13 | 2015-11-17 | 13,695 | $3.91 | $53.5K | 78,784 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise | 2015-11-13 | 2015-11-17 | 6,773 | $6.90 | $46.7K | 85,557 | SEC↗ |
| Gregg Richard | Chief Science Officer | M Exercise | 2015-11-13 | 2015-11-17 | 65,089 | $3.91 | $254.5K | 65,089 | SEC↗ |
| Bernstein Karen | Director | A Award deriv | 2015-09-30 | 2015-09-30 | 20,000 | — | $0 | 20,000 | SEC↗ |
| HAYDEN DONALD J JR | Director | M Exercise deriv | 2015-09-21 | 2015-09-22 | 16,130 | — | $0 | 18,065 | SEC↗ |
| HAYDEN DONALD J JR | Director | S Sale | 2015-09-21 | 2015-09-22 | 16,130 | $17.00 | $274.2K | 0 | SEC↗ |
| HAYDEN DONALD J JR | Director | M Exercise | 2015-09-21 | 2015-09-22 | 16,130 | $3.45 | $55.6K | 16,130 | SEC↗ |
| Fratamico Arthur | Chief Business Officer | P Buy | 2015-08-27 | 2015-08-31 | 10,000 | $7.83 | $78.3K | 10,000 | SEC↗ |
| LEONARD JOHN M. | Director | A Award deriv | 2015-07-29 | 2015-07-29 | 20,000 | — | $0 | 20,000 | SEC↗ |
| NEWHALL CHARLES W III | Director | J Other | 2015-07-01 | 2015-07-02 | 289 | — | $0 | 289 | SEC↗ |
| NEA PARTNERS 10 L P | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 825,000 | — | $0 | 1,786,564 | SEC↗ |
| NEA PARTNERS 10 L P | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 8,250 | — | $0 | 0 | SEC↗ |
| NEA PARTNERS 10 L P | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 8,250 | — | $0 | 8,250 | SEC↗ |
| NEW ENTERPRISE ASSOCIATES 10 L | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 825,000 | — | $0 | 1,786,564 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 8,250 | — | $0 | 0 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 1,134 | — | $0 | 1,134 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 556 | — | $0 | 556 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 8,250 | — | $0 | 8,250 | SEC↗ |
| SANDELL SCOTT D | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 825,000 | — | $0 | 1,786,564 | SEC↗ |
| BARRETT M JAMES | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 8,250 | — | $0 | 8,250 | SEC↗ |
| BARRETT M JAMES | 10% Owner | I Discretionary | 2015-07-01 | 2015-07-02 | 8,250 | — | $0 | 0 | SEC↗ |
| BARRETT M JAMES | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 1,134 | — | $0 | 1,134 | SEC↗ |
| BARRETT M JAMES | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 825,000 | — | $0 | 1,786,564 | SEC↗ |
| BARRETT M JAMES | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 464 | — | $0 | 464 | SEC↗ |
| BARRIS PETER J | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 1,134 | — | $0 | 1,134 | SEC↗ |
| BARRIS PETER J | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 8,250 | — | $0 | 0 | SEC↗ |
| BARRIS PETER J | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 386 | — | $0 | 386 | SEC↗ |
| BARRIS PETER J | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 97 | — | $0 | 97 | SEC↗ |
| BARRIS PETER J | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 1,171 | — | $0 | 1,171 | SEC↗ |
| BARRIS PETER J | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 825,000 | — | $0 | 1,786,564 | SEC↗ |
| BARRIS PETER J | 10% Owner | J Other | 2015-07-01 | 2015-07-02 | 8,250 | — | $0 | 8,250 | SEC↗ |
| NEWHALL CHARLES W III | Director | J Other | 2015-07-01 | 2015-07-10 | 289 | — | $0 | 289 | SEC↗ |
| Rowland Charles A Jr | Director | A Award deriv | 2015-05-28 | 2015-06-01 | 10,000 | — | $0 | 10,000 | SEC↗ |
| Gunderson Robert V JR | Director | A Award deriv | 2015-05-28 | 2015-06-01 | 10,000 | — | $0 | 10,000 | SEC↗ |
| NEWHALL CHARLES W III | Director | A Award deriv | 2015-05-28 | 2015-06-01 | 10,000 | — | $0 | 10,000 | SEC↗ |
| HAYDEN DONALD J JR | Director | A Award deriv | 2015-05-28 | 2015-06-01 | 10,000 | — | $0 | 10,000 | SEC↗ |
| SANTINI GINO | Director | A Award deriv | 2015-05-28 | 2015-06-01 | 10,000 | — | $0 | 10,000 | SEC↗ |
| ROBERTS BRYAN E | Director | A Award deriv | 2015-05-28 | 2015-06-01 | 10,000 | — | $0 | 10,000 | SEC↗ |
| HAYDEN DONALD J JR | Director | M Exercise deriv | 2015-05-20 | 2015-05-22 | 20,000 | — | $0 | 14,195 | SEC↗ |
| HAYDEN DONALD J JR | Director | M Exercise | 2015-05-20 | 2015-05-22 | 20,000 | $3.45 | $69.0K | 20,000 | SEC↗ |
| HAYDEN DONALD J JR | Director | S Sale | 2015-05-20 | 2015-05-22 | 20,000 | $12.01 | $240.2K | 0 | SEC↗ |
| SCHNELL DAVID | 10% Owner | J Other | 2015-03-24 | 2015-03-26 | 20,357 | — | $0 | 28,237 | SEC↗ |
| SCHNELL DAVID | 10% Owner | J Other | 2015-03-24 | 2015-03-26 | 20,357 | — | $0 | 32,584 | SEC↗ |
| SCHNELL DAVID | 10% Owner | J Other | 2015-03-24 | 2015-03-26 | 900,383 | — | $0 | 1,672,140 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | F Tax w/h | 2015-03-13 | 2015-03-17 | 171,156 | $11.16 | $1.91M | 267,360 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise deriv | 2015-03-06 | 2015-03-09 | 8,115 | $1.15 | $9.3K | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise | 2015-03-06 | 2015-03-09 | 8,115 | $1.15 | $9.3K | 438,516 | SEC↗ |
| Fratamico Arthur | Chief Business Officer | A Award deriv | 2015-02-13 | 2015-02-18 | 13,750 | — | $0 | 13,750 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | A Award deriv | 2015-02-13 | 2015-02-18 | 50,000 | — | $0 | 50,000 | SEC↗ |
| Morris Richard Steven | Chief Financial Officer | A Award deriv | 2015-02-13 | 2015-02-18 | 15,000 | — | $0 | 15,000 | SEC↗ |
| Gregg Richard | Chief Science Officer | A Award deriv | 2015-02-13 | 2015-02-18 | 21,250 | — | $0 | 21,250 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise deriv | 2015-01-22 | 2015-01-26 | 8,115 | — | $0 | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise deriv | 2015-01-22 | 2015-01-26 | 30,982 | — | $0 | 0 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise | 2015-01-22 | 2015-01-26 | 8,115 | $1.15 | $9.3K | 399,419 | SEC↗ |
| Hatfield Jeffrey S. | Chief Executive Officer | M Exercise | 2015-01-22 | 2015-01-26 | 30,982 | $1.15 | $35.6K | 430,401 | SEC↗ |
| Gunderson Robert V JR | Director | C Conversion deriv | 2014-09-29 | 2014-10-01 | 4,347 | — | $0 | 0 | SEC↗ |
| Gunderson Robert V JR | Director | C Conversion deriv | 2014-09-29 | 2014-10-01 | 4,454 | — | $0 | 0 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 3,563 | — | $0 | 0 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 9,285 | — | $0 | 0 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 41,270 | — | $0 | 0 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 32,086 | — | $0 | 0 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 142,607 | — | $0 | 0 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 1,031 | — | $0 | 0 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 227,117 | — | $0 | 0 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 1,009,414 | — | $0 | 0 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 25,233 | — | $0 | 0 | SEC↗ |
| Barrett Peter | Director | C Conversion deriv | 2014-09-29 | 2014-10-01 | 37,072 | — | $0 | 0 | SEC↗ |
| Barrett Peter | Director | C Conversion deriv | 2014-09-29 | 2014-10-01 | 1,099,743 | — | $0 | 0 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 1,009,414 | — | $0 | 0 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 142,607 | — | $0 | 0 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 3,563 | — | $0 | 0 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 227,117 | — | $0 | 0 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 32,086 | — | $0 | 0 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 25,233 | — | $0 | 0 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 9,285 | — | $0 | 0 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 41,270 | — | $0 | 0 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 1,031 | — | $0 | 0 | SEC↗ |
| BARRIS PETER J | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 172,825 | — | $0 | 0 | SEC↗ |
| BARRIS PETER J | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 58,692 | — | $0 | 0 | SEC↗ |
| BARRIS PETER J | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 1,479,058 | — | $0 | 0 | SEC↗ |
| PROSPECT MANAGEMENT CO LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 76,949 | — | $0 | 0 | SEC↗ |
| PROSPECT MANAGEMENT CO LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 1,530,269 | — | $0 | 0 | SEC↗ |
| PROSPECT MANAGEMENT CO LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 102,301 | — | $0 | 0 | SEC↗ |
| PROSPECT MANAGEMENT CO LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 173,912 | — | $0 | 0 | SEC↗ |
| PROSPECT MANAGEMENT CO LLC | 10% Owner | C Conversion deriv | 2014-09-29 | 2014-10-01 | 173,912 | — | $0 | 0 | SEC↗ |
| Gunderson Robert V JR | Director | C Conversion | 2014-09-29 | 2014-10-01 | 4,454 | — | $0 | 11,002 | SEC↗ |
| Gunderson Robert V JR | Director | C Conversion | 2014-09-29 | 2014-10-01 | 6,548 | — | $0 | 6,548 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | P Buy | 2014-09-29 | 2014-10-01 | 617,868 | $8.00 | $4.94M | 1,883,372 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | P Buy | 2014-09-29 | 2014-10-01 | 15,446 | $8.00 | $123.6K | 47,077 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 48,333 | — | $0 | 48,333 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 214,820 | — | $0 | 214,820 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | P Buy | 2014-09-29 | 2014-10-01 | 139,019 | $8.00 | $1.11M | 423,754 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 1,031 | — | $0 | 31,631 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 41,270 | — | $0 | 1,265,504 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 9,285 | — | $0 | 284,735 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 25,233 | — | $0 | 30,600 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 1,009,414 | — | $0 | 1,224,234 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 227,117 | — | $0 | 275,450 | SEC↗ |
| VENROCK MANAGEMENT III LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 5,367 | — | $0 | 5,367 | SEC↗ |
| Barrett Peter | Director | P Buy | 2014-09-29 | 2014-10-01 | 37,500 | $8.00 | $300.0K | 1,174,315 | SEC↗ |
| Barrett Peter | Director | C Conversion | 2014-09-29 | 2014-10-01 | 1,099,743 | — | $0 | 1,099,743 | SEC↗ |
| Barrett Peter | Director | C Conversion | 2014-09-29 | 2014-10-01 | 37,072 | — | $0 | 1,136,815 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | P Buy | 2014-09-29 | 2014-10-01 | 15,446 | $8.00 | $123.6K | 47,077 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | P Buy | 2014-09-29 | 2014-10-01 | 617,868 | $8.00 | $4.94M | 1,883,372 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | P Buy | 2014-09-29 | 2014-10-01 | 139,019 | $8.00 | $1.11M | 423,754 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 1,031 | — | $0 | 31,631 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 41,270 | — | $0 | 1,265,504 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 9,285 | — | $0 | 284,735 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 25,233 | — | $0 | 30,600 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 1,009,414 | — | $0 | 1,224,234 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 227,117 | — | $0 | 275,450 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 5,367 | — | $0 | 5,367 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 214,820 | — | $0 | 214,820 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 48,333 | — | $0 | 48,333 | SEC↗ |
| BARRIS PETER J | 10% Owner | P Buy | 2014-09-29 | 2014-10-01 | 813,474 | $8.00 | $6.51M | 2,611,564 | SEC↗ |
| BARRIS PETER J | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 260,340 | — | $0 | 260,340 | SEC↗ |
| BARRIS PETER J | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 1,479,058 | — | $0 | 1,739,398 | SEC↗ |
| BARRIS PETER J | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 58,692 | — | $0 | 1,798,090 | SEC↗ |
| PROSPECT MANAGEMENT CO LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 102,301 | — | $0 | 395,799 | SEC↗ |
| PROSPECT MANAGEMENT CO LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 1,530,269 | — | $0 | 1,823,767 | SEC↗ |
| PROSPECT MANAGEMENT CO LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 76,949 | — | $0 | 1,900,716 | SEC↗ |
| PROSPECT MANAGEMENT CO LLC | 10% Owner | P Buy | 2014-09-29 | 2014-10-01 | 671,807 | $8.00 | $5.37M | 2,572,523 | SEC↗ |
| PROSPECT MANAGEMENT CO LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 261,977 | — | $0 | 293,498 | SEC↗ |
| PROSPECT MANAGEMENT CO LLC | 10% Owner | C Conversion | 2014-09-29 | 2014-10-01 | 261,977 | — | $0 | 293,498 | SEC↗ |
| Gunderson Robert V JR | Director | A Award deriv | 2014-09-24 | 2014-09-26 | 17,000 | — | $0 | 17,000 | SEC↗ |
| Barrett Peter | Director | A Award deriv | 2014-09-24 | 2014-09-26 | 17,000 | — | $0 | 17,000 | SEC↗ |
| Rowland Charles A Jr | Director | A Award deriv | 2014-09-24 | 2014-09-26 | 17,000 | — | $0 | 17,000 | SEC↗ |
| NEWHALL CHARLES W III | Director | A Award deriv | 2014-09-24 | 2014-09-26 | 17,000 | — | $0 | 17,000 | SEC↗ |
| SANTINI GINO | Director | A Award deriv | 2014-09-24 | 2014-09-26 | 17,000 | — | $0 | 17,000 | SEC↗ |
| ROBERTS BRYAN E | Director, 10% Owner | A Award deriv | 2014-09-24 | 2014-09-26 | 17,000 | — | $0 | 17,000 | SEC↗ |
| HAYDEN DONALD J JR | Director | A Award deriv | 2014-09-24 | 2014-09-26 | 17,000 | — | $0 | 17,000 | SEC↗ |