XOMA

XOMA Royalty CorpCIK 791908 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

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0 trades · 0 insiders

Open-mkt sales · 90d

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0 trades · 0 insiders

Net · 90d

Insiders on file

AI insights for XOMA PRO

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AI insights for XOMA

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

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Insiders

Insider	Role	Trades	Bought	Sold	Last trade
BIOTECHNOLOGY VALUE FUND L P	Other	11	$1.02M	$16.98M	2026-07-14
Montano Maricel Perea	Chief Legal Officer	13	$0	$0	2026-07-14
Sitko Bradley	Chief Investment Officer	46	$417.8K	$0	2026-07-14
Trigilio Jeffrey	Chief Financial Officer	11	$0	$0	2026-07-14
Hernday Natasha	Director	16	$0	$0	2026-07-14
Kosacz Barbara	Director	18	$0	$0	2026-07-14
Hughes Owen	Interim CEO	29	$2.60M	$1.31M	2026-07-14
PERRY MATTHEW D	Director	20	$5.00M	$0	2026-07-14
Franklin Heather L	Director	12	$0	$0	2026-07-14
LIMBER JOSEPH M	Director	55	$760.1K	$0	2026-07-14
WYSZOMIERSKI JACK L	Director	52	$0	$0	2026-07-14
BVF PARTNERS L P/IL	Director, 10% Owner	19	$2.86M	$0	2026-05-14
BURNS THOMAS M.	VP, Finance & Chief Financial	80	$25.5K	$3.53M	2025-09-22
BVF GP HOLDINGS LLC	Director, 10% Owner	8	$409.3K	$10.64M	2025-05-16
BIOTECHNOLOGY VALUE FUND II LP	Other	12	$1.38M	$0	2023-01-06
BVF I GP LLC	Director, 10% Owner	13	$2.04M	$0	2022-09-16
Neal James R	VP Business Development	99	$84.0K	$7.04M	2022-07-15
Biotechnology Value Trading Fund OS LP	Other	14	$6.19M	$0	2022-05-18
VAN NESS W DENMAN	Director	55	$0	$72.0K	2022-05-18
BVF II GP LLC	10% Owner	12	$931.8K	$0	2021-05-19
BVF INC/IL	10% Owner	7	$527.2K	$25.00M	2021-03-31
BVF Partners OS Ltd.	Other	6	$942.1K	$0	2020-09-23
LAMPERT MARK N	10% Owner	8	$8.21M	$0	2019-12-19
DATTA DEEPSHIKHA	Chief Business Officer	3	$0	$0	2019-02-13
Varian John	Director and CEO	130	$0	$2.59M	2017-05-16
Walbert Timothy P	Director	31	$0	$0	2017-02-10
HUTT PETER BARTON	Director	7	$0	$0	2017-02-10
SCANNON PATRICK J MD PHD	Executive Vice President	65	$0	$674.6K	2016-12-21
RUBIN PAUL D	VP Clinical Dev. & CMO	125	$0	$1.11M	2016-03-22
667, L.P.	Other	6	$9.98M	$11.99M	2015-07-22
BOWES WILLIAM K JR	Director	26	$0	$0	2015-05-28
KURLAND FRED	CFO & VP Finance	45	$0	$216.8K	2015-04-06
Klein Thomas	Chief Commercial Officer	20	$0	$195.7K	2015-03-18
Baker Brothers Life Sciences LP	Director, 10% Owner	9	$0	$8.44M	2015-01-06
BAKER BROS. ADVISORS LP	Director, 10% Owner	30	$0	$20.93M	2014-12-30
Baker Bros. Advisors (GP) LLC	Director, 10% Owner	9	$0	$4.61M	2014-12-16
BAKER FELIX	Director, 10% Owner	17	$0	$1.81M	2014-12-09
14159, L.P.	Director, 10% Owner	3	$14.17M	$0	2012-10-29
Neu Kelvin	Director	2	$0	$0	2012-07-19

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Franklin Heather L	Director	D To issuer deriv	2026-07-14	2026-07-14	10,967	—	$0	0	SEC↗
Franklin Heather L	Director	D To issuer deriv	2026-07-14	2026-07-14	17,282	—	$0	0	SEC↗
Franklin Heather L	Director	D To issuer deriv	2026-07-14	2026-07-14	8,996	—	$0	0	SEC↗
Franklin Heather L	Director	D To issuer deriv	2026-07-14	2026-07-14	9,763	—	$0	0	SEC↗
Trigilio Jeffrey	Chief Financial Officer	D To issuer deriv	2026-07-14	2026-07-14	26,000	—	$0	0	SEC↗
Trigilio Jeffrey	Chief Financial Officer	D To issuer deriv	2026-07-14	2026-07-14	126,924	—	$0	0	SEC↗
PERRY MATTHEW D	Director	D To issuer deriv	2026-07-14	2026-07-14	8,996	—	$0	0	SEC↗
PERRY MATTHEW D	Director	D To issuer deriv	2026-07-14	2026-07-14	6,152	—	$0	0	SEC↗
PERRY MATTHEW D	Director	D To issuer deriv	2026-07-14	2026-07-14	10,967	—	$0	0	SEC↗
PERRY MATTHEW D	Director	D To issuer deriv	2026-07-14	2026-07-14	8,167	—	$0	0	SEC↗
PERRY MATTHEW D	Director	D To issuer deriv	2026-07-14	2026-07-14	5,052	—	$0	0	SEC↗
PERRY MATTHEW D	Director	D To issuer deriv	2026-07-14	2026-07-14	5,101	—	$0	0	SEC↗
PERRY MATTHEW D	Director	D To issuer deriv	2026-07-14	2026-07-14	15,222	—	$0	0	SEC↗
Hernday Natasha	Director	D To issuer deriv	2026-07-14	2026-07-14	4,881	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	D To issuer deriv	2026-07-14	2026-07-14	23,488	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	D To issuer deriv	2026-07-14	2026-07-14	41,112	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	D To issuer deriv	2026-07-14	2026-07-14	250,000	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	D To issuer deriv	2026-07-14	2026-07-14	300,000	—	$0	0	SEC↗
Hernday Natasha	Director	D To issuer deriv	2026-07-14	2026-07-14	5,101	—	$0	0	SEC↗
Hernday Natasha	Director	D To issuer deriv	2026-07-14	2026-07-14	13,251	—	$0	0	SEC↗
Hernday Natasha	Director	D To issuer deriv	2026-07-14	2026-07-14	10,967	—	$0	0	SEC↗
Hernday Natasha	Director	D To issuer deriv	2026-07-14	2026-07-14	8,996	—	$0	0	SEC↗
WYSZOMIERSKI JACK L	Director	D To issuer deriv	2026-07-14	2026-07-14	10,967	—	$0	0	SEC↗
WYSZOMIERSKI JACK L	Director	D To issuer deriv	2026-07-14	2026-07-14	8,996	—	$0	0	SEC↗
WYSZOMIERSKI JACK L	Director	D To issuer deriv	2026-07-14	2026-07-14	5,101	—	$0	0	SEC↗
WYSZOMIERSKI JACK L	Director	D To issuer deriv	2026-07-14	2026-07-14	6,152	—	$0	0	SEC↗
WYSZOMIERSKI JACK L	Director	D To issuer deriv	2026-07-14	2026-07-14	5,052	—	$0	0	SEC↗
WYSZOMIERSKI JACK L	Director	D To issuer deriv	2026-07-14	2026-07-14	8,167	—	$0	0	SEC↗
WYSZOMIERSKI JACK L	Director	D To issuer deriv	2026-07-14	2026-07-14	8,000	—	$0	0	SEC↗
WYSZOMIERSKI JACK L	Director	D To issuer deriv	2026-07-14	2026-07-14	2,366	—	$0	0	SEC↗
Hughes Owen	Chief Executive Officer	D To issuer deriv	2026-07-14	2026-07-14	75,000	—	$0	0	SEC↗
Hughes Owen	Chief Executive Officer	D To issuer deriv	2026-07-14	2026-07-14	100,000	—	$0	0	SEC↗
Hughes Owen	Chief Executive Officer	D To issuer deriv	2026-07-14	2026-07-14	132,714	—	$0	0	SEC↗
Hughes Owen	Chief Executive Officer	D To issuer deriv	2026-07-14	2026-07-14	116,245	—	$0	0	SEC↗
Kosacz Barbara	Director	D To issuer deriv	2026-07-14	2026-07-14	10,967	—	$0	0	SEC↗
Kosacz Barbara	Director	D To issuer deriv	2026-07-14	2026-07-14	8,996	—	$0	0	SEC↗
Kosacz Barbara	Director	D To issuer deriv	2026-07-14	2026-07-14	6,152	—	$0	0	SEC↗
Kosacz Barbara	Director	D To issuer deriv	2026-07-14	2026-07-14	5,101	—	$0	0	SEC↗
Kosacz Barbara	Director	D To issuer deriv	2026-07-14	2026-07-14	19,979	—	$0	0	SEC↗
Kosacz Barbara	Director	D To issuer deriv	2026-07-14	2026-07-14	8,167	—	$0	0	SEC↗
Kosacz Barbara	Director	D To issuer deriv	2026-07-14	2026-07-14	9,763	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	D To issuer deriv	2026-07-14	2026-07-14	9,936	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	D To issuer deriv	2026-07-14	2026-07-14	9,763	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	D To issuer deriv	2026-07-14	2026-07-14	10,967	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	D To issuer deriv	2026-07-14	2026-07-14	8,996	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	D To issuer deriv	2026-07-14	2026-07-14	5,101	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	D To issuer deriv	2026-07-14	2026-07-14	6,152	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	D To issuer deriv	2026-07-14	2026-07-14	8,167	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	D To issuer deriv	2026-07-14	2026-07-14	5,052	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	D To issuer deriv	2026-07-14	2026-07-14	2,366	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	D To issuer deriv	2026-07-14	2026-07-14	8,000	—	$0	0	SEC↗
Montano Maricel Perea	Chief Legal Officer	D To issuer deriv	2026-07-14	2026-07-14	11,316	—	$0	0	SEC↗
Montano Maricel Perea	Chief Legal Officer	D To issuer deriv	2026-07-14	2026-07-14	37,074	—	$0	0	SEC↗
Franklin Heather L	Director	J Other	2026-07-14	2026-07-14	6,269	—	$0	0	SEC↗
Trigilio Jeffrey	Chief Financial Officer	J Other	2026-07-14	2026-07-14	103,906	—	$0	0	SEC↗
PERRY MATTHEW D	Director	J Other	2026-07-14	2026-07-14	24,138	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	D To issuer	2026-07-14	2026-07-14	313	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	D To issuer	2026-07-14	2026-07-14	7,045	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	D To issuer	2026-07-14	2026-07-14	2,000	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	D To issuer	2026-07-14	2026-07-14	82	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	J Other	2026-07-14	2026-07-14	1,500	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	J Other	2026-07-14	2026-07-14	75	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	J Other	2026-07-14	2026-07-14	83,765	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	J Other	2026-07-14	2026-07-14	1,287	—	$0	0	SEC↗
Sitko Bradley	Chief Investment Officer	J Other	2026-07-14	2026-07-14	75	—	$0	0	SEC↗
Hernday Natasha	Director	D To issuer	2026-07-14	2026-07-14	4,000	—	$0	0	SEC↗
Hernday Natasha	Director	J Other	2026-07-14	2026-07-14	9,304	—	$0	0	SEC↗
WYSZOMIERSKI JACK L	Director	J Other	2026-07-14	2026-07-14	21,828	—	$0	0	SEC↗
Hughes Owen	Chief Executive Officer	J Other	2026-07-14	2026-07-14	752	—	$0	0	SEC↗
Hughes Owen	Chief Executive Officer	J Other	2026-07-14	2026-07-14	191,264	—	$0	0	SEC↗
Hughes Owen	Chief Executive Officer	D To issuer	2026-07-14	2026-07-14	102,000	—	$0	0	SEC↗
Kosacz Barbara	Director	J Other	2026-07-14	2026-07-14	6,269	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	J Other	2026-07-14	2026-07-14	9,532	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	D To issuer	2026-07-14	2026-07-14	10,000	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	D To issuer	2026-07-14	2026-07-14	20,000	—	$0	0	SEC↗
Montano Maricel Perea	Chief Legal Officer	J Other	2026-07-14	2026-07-14	65	—	$0	0	SEC↗
Montano Maricel Perea	Chief Legal Officer	J Other	2026-07-14	2026-07-14	42,306	—	$0	0	SEC↗
BIOTECHNOLOGY VALUE FUND L P	10% Owner	U Tender	2026-07-14	2026-07-16	772,000	—	$0	0	SEC↗
BIOTECHNOLOGY VALUE FUND L P	10% Owner	U Tender	2026-07-14	2026-07-16	3,635,758	—	$0	0	SEC↗
BIOTECHNOLOGY VALUE FUND L P	10% Owner	U Tender	2026-07-14	2026-07-16	2,773,545	—	$0	0	SEC↗
BIOTECHNOLOGY VALUE FUND L P	10% Owner	U Tender	2026-07-14	2026-07-16	412,000	—	$0	0	SEC↗
Kosacz Barbara	Director	A Award	2026-05-21	2026-05-26	3,586	—	$0	9,557	SEC↗
Franklin Heather L	Director	A Award	2026-05-21	2026-05-26	3,586	—	$0	9,557	SEC↗
PERRY MATTHEW D	Director	A Award	2026-05-21	2026-05-26	3,586	—	$0	27,426	SEC↗
Hernday Natasha	Director	A Award	2026-05-21	2026-05-26	3,586	—	$0	12,592	SEC↗
LIMBER JOSEPH M	Director	A Award	2026-05-21	2026-05-26	3,586	—	$0	12,820	SEC↗
WYSZOMIERSKI JACK L	Director	A Award	2026-05-21	2026-05-26	3,586	—	$0	25,116	SEC↗
BVF PARTNERS L P/IL	10% Owner	C Conversion deriv	2026-05-14	2026-05-18	412	—	$0	0	SEC↗
BVF PARTNERS L P/IL	10% Owner	C Conversion deriv	2026-05-14	2026-05-18	2,313	—	$0	0	SEC↗
BVF PARTNERS L P/IL	10% Owner	C Conversion deriv	2026-05-14	2026-05-18	1,506	—	$0	0	SEC↗
BVF PARTNERS L P/IL	10% Owner	C Conversion deriv	2026-05-14	2026-05-18	772	—	$0	0	SEC↗
BVF PARTNERS L P/IL	10% Owner	C Conversion	2026-05-14	2026-05-18	772,000	$4.03	$3.11M	772,000	SEC↗
BVF PARTNERS L P/IL	10% Owner	C Conversion	2026-05-14	2026-05-18	412,000	$4.03	$1.66M	412,000	SEC↗
BVF PARTNERS L P/IL	10% Owner	C Conversion	2026-05-14	2026-05-18	1,506,000	$4.03	$6.07M	2,773,545	SEC↗
BVF PARTNERS L P/IL	10% Owner	C Conversion	2026-05-14	2026-05-18	2,313,000	$4.03	$9.32M	3,635,758	SEC↗
Sitko Bradley	Chief Investment Officer	M Exercise deriv	2026-04-20	2026-04-22	3,737	—	$0	41,112	SEC↗
Hughes Owen	Chief Executive Officer	M Exercise deriv	2026-04-20	2026-04-22	10,568	—	$0	116,245	SEC↗
Montano Maricel Perea	Chief Legal Officer	M Exercise deriv	2026-04-20	2026-04-22	3,370	—	$0	37,074	SEC↗
Trigilio Jeffrey	Chief Financial Officer	M Exercise deriv	2026-04-20	2026-04-22	11,538	—	$0	126,924	SEC↗
Sitko Bradley	Chief Investment Officer	M Exercise	2026-04-20	2026-04-22	3,737	—	$0	82,961	SEC↗
Hughes Owen	Chief Executive Officer	M Exercise	2026-04-20	2026-04-22	10,568	—	$0	191,264	SEC↗
Montano Maricel Perea	Chief Legal Officer	M Exercise	2026-04-20	2026-04-22	3,370	—	$0	41,793	SEC↗
Trigilio Jeffrey	Chief Financial Officer	M Exercise	2026-04-20	2026-04-22	11,538	—	$0	103,906	SEC↗
Trigilio Jeffrey	Chief Financial Officer	M Exercise deriv	2026-04-13	2026-04-15	4,000	—	$0	26,000	SEC↗
Trigilio Jeffrey	Chief Financial Officer	M Exercise	2026-04-13	2026-04-15	4,000	—	$0	94,000	SEC↗
Trigilio Jeffrey	Chief Financial Officer	F Tax w/h	2026-04-13	2026-04-15	1,632	$36.76	$60.0K	92,368	SEC↗
LIMBER JOSEPH M	Director	M Exercise deriv	2026-03-27	2026-03-31	3,026	—	$0	0	SEC↗
LIMBER JOSEPH M	Director	M Exercise	2026-03-27	2026-03-31	3,026	$11.20	$33.9K	9,234	SEC↗
WYSZOMIERSKI JACK L	Director	M Exercise deriv	2026-03-24	2026-03-26	3,026	—	$0	0	SEC↗
WYSZOMIERSKI JACK L	Director	M Exercise	2026-03-24	2026-03-26	3,026	$11.20	$33.9K	21,530	SEC↗
Hughes Owen	Chief Executive Officer	A Award deriv	2026-03-16	2026-03-17	126,813	—	$0	126,813	SEC↗
Hughes Owen	Chief Executive Officer	A Award	2026-03-16	2026-03-17	82,428	—	$0	180,696	SEC↗
Montano Maricel Perea	Chief Legal Officer	A Award deriv	2026-03-11	2026-03-13	40,444	—	$0	40,444	SEC↗
Trigilio Jeffrey	Chief Financial Officer	A Award deriv	2026-03-11	2026-03-13	138,462	—	$0	138,462	SEC↗
Sitko Bradley	Chief Investment Officer	A Award deriv	2026-03-11	2026-03-13	44,849	—	$0	44,849	SEC↗
Montano Maricel Perea	Chief Legal Officer	A Award	2026-03-11	2026-03-13	26,289	—	$0	38,423	SEC↗
Trigilio Jeffrey	Chief Financial Officer	A Award	2026-03-11	2026-03-13	90,000	—	$0	90,000	SEC↗
Sitko Bradley	Chief Investment Officer	A Award	2026-03-11	2026-03-13	29,402	—	$0	79,224	SEC↗
Sitko Bradley	Chief Investment Officer	A Award	2026-03-11	2026-03-13	30,000	—	$0	49,822	SEC↗
Trigilio Jeffrey	Chief Financial Officer	A Award deriv	2026-01-12	2026-01-14	30,000	—	$0	30,000	SEC↗
Hughes Owen	Chief Executive Officer	P Buy	2025-12-04	2025-12-08	100,000	$25.05	$2.50M	102,000	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	S Sale	2025-09-22	2025-09-23	15	$36.93	$554	30,094	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	S Sale	2025-09-22	2025-09-23	4,300	$35.98	$154.7K	30,109	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	S Sale	2025-09-22	2025-09-23	15	$36.81	$552	30,079	SEC↗
Montano Maricel Perea	Chief Legal Officer	M Exercise deriv	2025-09-19	2025-09-23	3,033	—	$0	11,316	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise deriv	2025-09-19	2025-09-23	11,846	—	$0	44,208	SEC↗
Hughes Owen	Chief Executive Officer	M Exercise deriv	2025-09-19	2025-09-23	35,567	—	$0	132,714	SEC↗
Sitko Bradley	Chief Investment Officer	M Exercise deriv	2025-09-19	2025-09-23	6,712	—	$0	23,488	SEC↗
Montano Maricel Perea	Chief Legal Officer	M Exercise	2025-09-19	2025-09-23	3,033	—	$0	12,134	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise	2025-09-19	2025-09-23	11,846	—	$0	34,409	SEC↗
Hughes Owen	Chief Executive Officer	M Exercise	2025-09-19	2025-09-23	35,567	—	$0	98,268	SEC↗
Sitko Bradley	Chief Investment Officer	M Exercise	2025-09-19	2025-09-23	6,712	—	$0	19,822	SEC↗
Montano Maricel Perea	Chief Legal Officer	M Exercise deriv	2025-09-10	2025-09-12	9,101	—	$0	14,349	SEC↗
Montano Maricel Perea	Chief Legal Officer	M Exercise	2025-09-10	2025-09-12	9,101	—	$0	9,101	SEC↗
Montano Maricel Perea	Chief Legal Officer	A Award deriv	2025-08-12	2025-08-14	23,450	—	$0	23,450	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2025-06-30	2025-07-02	2,000	$25.39	$50.8K	7,045	SEC↗
LIMBER JOSEPH M	Director	A Award deriv	2025-05-21	2025-05-23	9,936	—	$0	9,936	SEC↗
Kosacz Barbara	Director	A Award	2025-05-21	2025-05-23	5,971	—	$0	5,971	SEC↗
Franklin Heather L	Director	A Award	2025-05-21	2025-05-23	5,971	—	$0	5,971	SEC↗
Hernday Natasha	Director	A Award	2025-05-21	2025-05-23	5,971	—	$0	9,006	SEC↗
PERRY MATTHEW D	Director	A Award	2025-05-21	2025-05-23	5,971	—	$0	23,840	SEC↗
WYSZOMIERSKI JACK L	Director	A Award	2025-05-21	2025-05-23	5,971	—	$0	18,504	SEC↗
Kosacz Barbara	Director	A Award	2025-05-21	2025-05-23	5,971	—	$0	5,971	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	S Sale	2025-05-20	2025-05-21	10,482	$25.38	$266.0K	22,563	SEC↗
Hughes Owen	Chief Executive Officer	S Sale	2025-05-20	2025-05-21	25,637	$25.38	$650.7K	62,701	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise deriv	2025-05-19	2025-05-21	17,773	—	$0	56,054	SEC↗
Hughes Owen	Chief Executive Officer	M Exercise deriv	2025-05-19	2025-05-21	53,359	—	$0	168,281	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise	2025-05-19	2025-05-21	17,773	—	$0	33,045	SEC↗
Hughes Owen	Chief Executive Officer	M Exercise	2025-05-19	2025-05-21	53,359	—	$0	88,338	SEC↗
BVF GP HOLDINGS LLC	10% Owner	S Sale	2025-05-16	2025-05-20	265,316	$27.10	$7.19M	1,267,545	SEC↗
BVF GP HOLDINGS LLC	10% Owner	S Sale	2025-05-16	2025-05-20	127,407	$27.10	$3.45M	1,322,758	SEC↗
LIMBER JOSEPH M	Director	P Buy	2025-04-07	2025-04-07	5,243	$25.60	$134.2K	10,000	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2025-04-07	2025-04-09	2,000	$24.70	$49.4K	5,045	SEC↗
LIMBER JOSEPH M	Director	P Buy	2025-04-04	2025-04-07	3,346	$25.56	$85.5K	4,757	SEC↗
LIMBER JOSEPH M	Director	P Buy	2025-04-04	2025-04-07	3,476	$25.25	$87.8K	20,000	SEC↗
LIMBER JOSEPH M	Director	P Buy	2025-04-03	2025-04-07	16,524	$25.22	$416.7K	16,524	SEC↗
LIMBER JOSEPH M	Director	P Buy	2025-04-03	2025-04-07	1,411	$25.44	$35.9K	1,411	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	P Buy	2025-04-01	2025-04-02	1,000	$25.46	$25.5K	2,000	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2025-03-31	2025-04-02	1,000	$19.98	$20.0K	11,484	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2025-03-31	2025-04-02	245	$25.39	$6.2K	3,045	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2025-03-21	2025-03-25	2,800	$25.43	$71.2K	2,800	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2025-03-21	2025-03-25	1,334	$20.65	$27.5K	10,484	SEC↗
BIOTECHNOLOGY VALUE FUND L P	10% Owner	S Sale	2025-01-24	2025-01-28	339,679	$26.10	$8.87M	1,450,165	SEC↗
BIOTECHNOLOGY VALUE FUND L P	10% Owner	S Sale	2025-01-24	2025-01-28	149,975	$26.10	$3.91M	0	SEC↗
BIOTECHNOLOGY VALUE FUND L P	10% Owner	S Sale	2025-01-24	2025-01-28	85,776	$26.10	$2.24M	1,532,861	SEC↗
BIOTECHNOLOGY VALUE FUND L P	10% Owner	S Sale	2025-01-24	2025-01-28	75,287	$26.10	$1.96M	0	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2025-01-08	2025-01-10	75	$25.60	$1.9K	75	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2025-01-08	2025-01-10	82	$25.60	$2.1K	82	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2025-01-08	2025-01-10	75	$25.90	$1.9K	75	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2025-01-08	2025-01-10	313	$25.60	$8.0K	313	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2024-12-31	2025-01-03	300	$25.90	$7.8K	9,150	SEC↗
Hughes Owen	Chief Executive Officer	S Sale	2024-11-13	2024-11-13	21,881	$29.95	$655.3K	34,979	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	S Sale	2024-11-13	2024-11-13	9,775	$29.94	$292.7K	14,553	SEC↗
Hughes Owen	Chief Executive Officer	M Exercise deriv	2024-11-11	2024-11-13	53,360	—	$0	221,640	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise deriv	2024-11-11	2024-11-13	17,773	—	$0	73,827	SEC↗
Hughes Owen	Chief Executive Officer	M Exercise	2024-11-11	2024-11-13	53,360	—	$0	56,860	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise	2024-11-11	2024-11-13	17,773	—	$0	24,328	SEC↗
LIMBER JOSEPH M	Director	A Award deriv	2024-05-15	2024-05-17	9,763	—	$0	9,763	SEC↗
Franklin Heather L	Director	A Award deriv	2024-05-15	2024-05-17	9,763	—	$0	9,763	SEC↗
Hernday Natasha	Director	A Award deriv	2024-05-15	2024-05-17	4,881	—	$0	4,881	SEC↗
Kosacz Barbara	Director	A Award deriv	2024-05-15	2024-05-17	9,763	—	$0	9,763	SEC↗
PERRY MATTHEW D	Director	A Award	2024-05-15	2024-05-17	6,070	—	$0	17,869	SEC↗
WYSZOMIERSKI JACK L	Director	A Award	2024-05-15	2024-05-17	6,070	—	$0	12,533	SEC↗
Hernday Natasha	Director	A Award	2024-05-15	2024-05-17	3,035	—	$0	3,035	SEC↗
Hughes Owen	Chief Executive Officer	A Award deriv	2024-01-08	2024-01-10	275,000	—	$0	275,000	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2023-10-03	2023-10-04	250	$13.89	$3.5K	5,600	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2023-10-02	2023-10-04	1,500	$14.25	$21.4K	5,350	SEC↗
Hughes Owen	Exec Chairman and Interim CE	P Buy	2023-10-02	2023-10-04	1,000	$13.83	$13.8K	3,500	SEC↗
Hughes Owen	Exec Chairman and Interim CE	P Buy	2023-09-26	2023-09-27	2,499	$14.43	$36.1K	2,500	SEC↗
Hughes Owen	Exec Chairman and Interim CE	P Buy	2023-09-25	2023-09-27	1	$14.65	$15	1	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2023-05-31	2023-06-02	500	$17.00	$8.5K	2,500	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2023-05-31	2023-06-02	1,000	$17.20	$17.2K	3,500	SEC↗
Hughes Owen	Interim CEO	P Buy	2023-05-24	2023-05-25	1,032	$23.79	$24.6K	2,000	SEC↗
Hughes Owen	Interim CEO	P Buy	2023-05-23	2023-05-25	200	$23.33	$4.7K	200	SEC↗
Hughes Owen	Interim CEO	P Buy	2023-05-23	2023-05-25	768	$23.49	$18.0K	968	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2023-05-23	2023-05-25	850	$19.00	$16.1K	3,850	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2023-05-19	2023-05-22	1,000	$19.50	$19.5K	3,000	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	A Award deriv	2023-05-18	2023-05-22	91,600	—	$0	91,600	SEC↗
Sitko Bradley	Chief Investment Officer	A Award deriv	2023-05-18	2023-05-22	30,200	—	$0	30,200	SEC↗
Franklin Heather L	Director	A Award deriv	2023-05-17	2023-05-19	10,967	—	$0	10,967	SEC↗
Hernday Natasha	Director	A Award deriv	2023-05-17	2023-05-19	10,967	—	$0	10,967	SEC↗
Kosacz Barbara	Director	A Award deriv	2023-05-17	2023-05-19	10,967	—	$0	10,967	SEC↗
LIMBER JOSEPH M	Director	A Award deriv	2023-05-17	2023-05-19	10,967	—	$0	10,967	SEC↗
WYSZOMIERSKI JACK L	Director	A Award deriv	2023-05-17	2023-05-19	10,967	—	$0	10,967	SEC↗
PERRY MATTHEW D	Director	A Award deriv	2023-05-17	2023-05-19	10,967	—	$0	10,967	SEC↗
BVF PARTNERS L P/IL	Director, 10% Owner	A Award deriv	2023-05-17	2023-05-19	10,967	—	$0	10,967	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2023-05-16	2023-05-17	100	$23.20	$2.3K	1,900	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2023-05-16	2023-05-17	100	$23.25	$2.3K	2,000	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2023-05-16	2023-05-17	300	$23.19	$7.0K	1,800	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2023-05-15	2023-05-16	1,500	$23.40	$35.1K	1,500	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2023-05-12	2023-05-16	1,957	$19.00	$37.2K	2,000	SEC↗
Sitko Bradley	Chief Investment Officer	P Buy	2023-05-12	2023-05-16	43	$18.66	$802	43	SEC↗
BIOTECHNOLOGY VALUE FUND II LP	Director, 10% Owner	P Buy	2023-01-06	2023-01-09	1,676	$21.98	$36.8K	1,789,844	SEC↗
BIOTECHNOLOGY VALUE FUND II LP	Director, 10% Owner	P Buy	2023-01-06	2023-01-09	1,573	$21.98	$34.6K	1,618,637	SEC↗
BIOTECHNOLOGY VALUE FUND II LP	Director, 10% Owner	P Buy	2023-01-05	2023-01-09	3,330	$18.39	$61.2K	1,788,168	SEC↗
BIOTECHNOLOGY VALUE FUND II LP	Director, 10% Owner	P Buy	2023-01-05	2023-01-09	15,670	$18.39	$288.2K	1,617,064	SEC↗
Hughes Owen	Interim CEO	A Award deriv	2023-01-03	2023-01-05	100,000	—	$0	100,000	SEC↗
Hughes Owen	Interim CEO	A Award deriv	2023-01-03	2023-01-05	75,000	—	$0	75,000	SEC↗
Sitko Bradley	Chief Investment Officer	A Award deriv	2023-01-03	2023-01-06	250,000	—	$0	250,000	SEC↗
Sitko Bradley	Chief Investment Officer	A Award deriv	2023-01-03	2023-01-06	300,000	—	$0	300,000	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	A Award deriv	2022-11-08	2022-11-09	11,000	—	$0	11,000	SEC↗
BVF GP HOLDINGS LLC	Director, 10% Owner	P Buy	2022-09-27	2022-09-27	678	$16.89	$11.5K	1,601,394	SEC↗
BVF GP HOLDINGS LLC	Director, 10% Owner	P Buy	2022-09-27	2022-09-27	1,004	$16.89	$17.0K	1,784,838	SEC↗
BVF GP HOLDINGS LLC	Director, 10% Owner	P Buy	2022-09-26	2022-09-27	3,339	$16.83	$56.2K	1,783,834	SEC↗
BVF GP HOLDINGS LLC	Director, 10% Owner	P Buy	2022-09-26	2022-09-27	3,021	$16.83	$50.8K	1,600,716	SEC↗
BVF GP HOLDINGS LLC	Director, 10% Owner	P Buy	2022-09-23	2022-09-27	6,715	$16.50	$110.8K	1,780,495	SEC↗
BVF GP HOLDINGS LLC	Director, 10% Owner	P Buy	2022-09-23	2022-09-27	9,885	$16.50	$163.1K	1,597,695	SEC↗
BVF I GP LLC	Director, 10% Owner	P Buy	2022-09-16	2022-09-16	10,897	$17.89	$194.9K	1,587,810	SEC↗
BVF I GP LLC	Director, 10% Owner	P Buy	2022-09-16	2022-09-16	13,396	$17.89	$239.7K	1,773,780	SEC↗
BVF I GP LLC	Director, 10% Owner	P Buy	2022-09-15	2022-09-16	5,575	$17.96	$100.1K	1,576,913	SEC↗
BVF I GP LLC	Director, 10% Owner	P Buy	2022-09-14	2022-09-16	26,441	$17.25	$456.1K	1,571,338	SEC↗
Neal James R	CEO	M Exercise deriv	2022-07-15	2022-07-18	25,000	—	$0	218,056	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise deriv	2022-07-15	2022-07-18	2,000	—	$0	75,778	SEC↗
Neal James R	CEO	S Sale	2022-07-15	2022-07-18	905	$31.86	$28.8K	11,822	SEC↗
Neal James R	CEO	S Sale	2022-07-15	2022-07-18	3,212	$31.19	$100.2K	12,727	SEC↗
Neal James R	CEO	M Exercise	2022-07-15	2022-07-18	25,000	$4.03	$100.8K	36,822	SEC↗
Neal James R	CEO	S Sale	2022-07-15	2022-07-18	20,883	$29.55	$617.1K	15,939	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	S Sale	2022-07-15	2022-07-18	2,000	$31.66	$63.3K	6,555	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise	2022-07-15	2022-07-18	2,000	$4.03	$8.1K	8,555	SEC↗
Franklin Heather L	Director	A Award deriv	2022-05-18	2022-05-20	8,996	—	$0	8,996	SEC↗
Kosacz Barbara	Director	A Award deriv	2022-05-18	2022-05-20	8,996	—	$0	8,996	SEC↗
WYSZOMIERSKI JACK L	Director	A Award deriv	2022-05-18	2022-05-20	8,996	—	$0	8,996	SEC↗
LIMBER JOSEPH M	Director	A Award deriv	2022-05-18	2022-05-20	8,996	—	$0	8,996	SEC↗
VAN NESS W DENMAN	Director	A Award deriv	2022-05-18	2022-05-20	8,996	—	$0	8,996	SEC↗
Hernday Natasha	Director	A Award deriv	2022-05-18	2022-05-20	8,996	—	$0	8,996	SEC↗
PERRY MATTHEW D	Director	A Award deriv	2022-05-18	2022-05-20	8,996	—	$0	8,996	SEC↗
Biotechnology Value Trading Fu	Director	A Award deriv	2022-05-18	2022-05-20	8,996	—	$0	8,996	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise deriv	2022-03-23	2022-03-23	161	—	$0	15,500	SEC↗
Neal James R	CEO	M Exercise deriv	2022-03-23	2022-03-23	1,111	—	$0	102,800	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise	2022-03-23	2022-03-23	161	$4.03	$649	6,716	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	S Sale	2022-03-23	2022-03-23	161	$30.00	$4.8K	6,555	SEC↗
Neal James R	CEO	M Exercise	2022-03-23	2022-03-23	1,111	$4.03	$4.5K	12,933	SEC↗
Neal James R	CEO	S Sale	2022-03-23	2022-03-23	1,111	$30.02	$33.4K	11,822	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise deriv	2022-03-22	2022-03-23	2,339	—	$0	15,661	SEC↗
Neal James R	CEO	M Exercise deriv	2022-03-22	2022-03-23	2,339	—	$0	103,911	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise	2022-03-22	2022-03-23	2,339	$4.03	$9.4K	8,894	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	S Sale	2022-03-22	2022-03-23	2,339	$30.02	$70.2K	6,555	SEC↗
Neal James R	CEO	S Sale	2022-03-22	2022-03-23	2,339	$30.02	$70.2K	11,822	SEC↗
Neal James R	CEO	M Exercise	2022-03-22	2022-03-23	2,339	$4.03	$9.4K	14,161	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise deriv	2022-03-21	2022-03-23	12,000	—	$0	18,000	SEC↗
Neal James R	CEO	M Exercise deriv	2022-03-21	2022-03-23	50,000	—	$0	106,250	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise	2022-03-21	2022-03-23	12,000	$4.03	$48.4K	18,555	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	S Sale	2022-03-21	2022-03-23	12,000	$29.01	$348.1K	6,555	SEC↗
Neal James R	CEO	M Exercise	2022-03-21	2022-03-23	50,000	$4.03	$201.5K	61,822	SEC↗
Neal James R	CEO	S Sale	2022-03-21	2022-03-23	50,000	$29.01	$1.45M	11,822	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	A Award deriv	2022-02-22	2022-02-23	28,000	—	$0	28,000	SEC↗
Neal James R	CEO	A Award deriv	2021-12-21	2021-12-23	60,000	—	$0	60,000	SEC↗
Franklin Heather L	Director	A Award deriv	2021-08-06	2021-08-10	13,136	—	$0	13,136	SEC↗
Franklin Heather L	Director	A Award deriv	2021-08-06	2021-08-10	4,146	—	$0	4,146	SEC↗
Neal James R	CEO	S Sale	2021-06-25	2021-06-29	686	$35.13	$24.1K	11,822	SEC↗
Neal James R	CEO	S Sale	2021-06-25	2021-06-29	7,170	$33.36	$239.2K	13,679	SEC↗
Neal James R	CEO	S Sale	2021-06-25	2021-06-29	1,171	$34.30	$40.2K	12,508	SEC↗
Hernday Natasha	Director	A Award deriv	2021-05-19	2021-05-21	5,101	—	$0	5,101	SEC↗
Kosacz Barbara	Director	A Award deriv	2021-05-19	2021-05-21	5,101	—	$0	5,101	SEC↗
VAN NESS W DENMAN	Director	A Award deriv	2021-05-19	2021-05-21	5,101	—	$0	5,101	SEC↗
LIMBER JOSEPH M	Director	A Award deriv	2021-05-19	2021-05-21	5,101	—	$0	5,101	SEC↗
WYSZOMIERSKI JACK L	Director	A Award deriv	2021-05-19	2021-05-21	5,101	—	$0	5,101	SEC↗
PERRY MATTHEW D	Director	A Award deriv	2021-05-19	2021-05-21	5,101	—	$0	5,101	SEC↗
BVF II GP LLC	10% Owner	A Award deriv	2021-05-19	2021-05-21	5,101	—	$0	5,101	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	A Award	2021-04-09	2021-04-13	1,000	$25.00	$25.0K	1,000	SEC↗
Neal James R	CEO	A Award	2021-04-09	2021-04-13	8,000	$25.00	$200.0K	8,000	SEC↗
BVF INC/IL	10% Owner	S Sale	2021-03-31	2021-04-02	279,740	$38.36	$10.73M	1,760,384	SEC↗
BVF INC/IL	10% Owner	S Sale	2021-03-31	2021-04-02	81,903	$38.36	$3.14M	149,975	SEC↗
BVF INC/IL	10% Owner	S Sale	2021-03-31	2021-04-02	84,250	$38.36	$3.23M	75,287	SEC↗
BVF INC/IL	10% Owner	S Sale	2021-03-31	2021-04-02	205,807	$38.36	$7.89M	1,544,897	SEC↗
VAN NESS W DENMAN	Director	M Exercise deriv	2021-03-15	2021-03-16	3,333	—	$0	0	SEC↗
VAN NESS W DENMAN	Director	M Exercise deriv	2021-03-15	2021-03-16	2,366	—	$0	0	SEC↗
VAN NESS W DENMAN	Director	M Exercise	2021-03-15	2021-03-16	2,366	$19.40	$45.9K	12,310	SEC↗
VAN NESS W DENMAN	Director	M Exercise	2021-03-15	2021-03-16	3,333	$4.03	$13.4K	15,643	SEC↗
Neal James R	CEO	A Award deriv	2021-02-17	2021-02-19	60,268	—	$0	60,268	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	A Award deriv	2021-02-17	2021-02-19	20,055	—	$0	20,055	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise deriv	2020-12-15	2020-12-17	15,000	—	$0	7,000	SEC↗
Neal James R	CEO	M Exercise deriv	2020-12-15	2020-12-17	26,000	—	$0	0	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	M Exercise	2020-12-15	2020-12-17	15,000	$4.03	$60.5K	21,555	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	S Sale	2020-12-15	2020-12-17	5,607	$42.04	$235.7K	6,555	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	A Award	2020-12-15	2020-12-17	2,000	$25.00	$50.0K	2,000	SEC↗
BURNS THOMAS M.	SVP, Finance & CFO	S Sale	2020-12-15	2020-12-17	9,393	$41.02	$385.3K	12,162	SEC↗
Hernday Natasha	Director	A Award	2020-12-15	2020-12-17	4,000	$25.00	$100.0K	4,000	SEC↗
Neal James R	CEO	S Sale	2020-12-15	2020-12-17	20,294	$41.15	$835.1K	26,555	SEC↗
Neal James R	CEO	M Exercise	2020-12-15	2020-12-17	26,000	$5.50	$143.0K	46,849	SEC↗