ZYME

Zymeworks Inc.CIK 1937653 ☆ Sign in to watch Congress trades

Open-mkt buys · 90d

—

0 trades · 0 insiders

Open-mkt sales · 90d

$357.6K

1 trades · 1 insiders

Net · 90d

$-357.6K

Insiders on file

AI insights for ZYME PRO

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AI insights for ZYME

Insider sentiment score with a plain-English explanation, conviction score on every buy, and how the stock performed 30 and 90 days after past insider buys.

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Daily buy vs sell · 90 days

■ Open-market buys (P) ■ Open-market sales (S) · daily dollar value by transaction date

Insiders

Insider	Role	Trades	Bought	Sold	Last trade
Schayowitz Adam	See Remarks	6	$0	$357.6K	2026-10-09
Hollywood Mark	EVP & Chief Operating Officer	7	$0	$138.7K	2026-07-06
Schneider Paul R	EVP, General Counsel	2	$0	$0	2026-05-13
Platshon Scott	EVP, Chief Business Officer	3	$0	$0	2026-04-09
Stafford Kristin	EVP, Chief Financial Officer	3	$0	$0	2026-04-06
Ciongoli Gregory Austin	Director	4	$0	$0	2026-01-12
Moore Paul Andrew	Chief Scientific Officer	29	$0	$1.14M	2026-01-12
Cesano Alessandra	Director	4	$0	$0	2026-01-12
Campoy Carlos	Director	5	$0	$0	2026-01-12
Smith Jeffrey T L	EVP & Chief Medical Officer	13	$0	$641.3K	2026-01-12
Landry Robert E	Director	3	$0	$0	2026-01-12
Galbraith Kenneth	Chair, President & CEO	33	$0	$4.45M	2026-01-12
Neu Kelvin	Director	6	$0	$0	2026-01-12
Mahony Susan	Director	7	$0	$0	2026-01-12
Cherry Brian N	Director	2	$0	$0	2026-01-12
PATTERSON LEONE D	EVP, Chief Bus & Fin Officer	4	$0	$0	2026-01-06
NODELMAN OLEG	Director, 10% Owner	8	$16.74M	$0	2025-06-26
EcoR1 Capital, LLC	Director, 10% Owner	42	$190.65M	$0	2025-05-19
Davidson Nancy	Director	2	$0	$0	2024-12-10
Gallagher Neil	Director	2	$0	$0	2024-12-10
Miller Derek John Michael	Director	3	$0	$0	2024-12-10
Cox Troy	Director	6	$348.8K	$0	2024-12-10
Astle Christopher	SVP & Chief Financial Officer	18	$0	$83.4K	2024-01-08
Hillan Kenneth J.	Director	5	$0	$0	2023-12-07
RENTON HOLLINGS	Director	5	$0	$0	2023-12-07
Klompas Neil A	President & COO	45	$0	$2.92M	2023-03-10
Sacks Natalie	Director	4	$0	$0	2022-12-21
Zoth Lota S.	Director	4	$0	$0	2022-12-21
Josephson Neil	Interim Chief Medical Officer	20	$71.4K	$60.1K	2022-11-10
Redmile Group, LLC	10% Owner	2	$153.3K	$0	2022-10-13
Polverino Anthony J.	Chief Scientific Officer	18	$0	$36.6K	2022-01-07
Tehrani Ali	Chief Executive Officer	24	$19.2K	$2.46M	2021-07-16
Priour James	Chief Commercial Officer	6	$0	$26.5K	2021-07-06
O'Driscoll Kathryn	Chief People Officer	16	$0	$47.1K	2021-07-06
HAUSMAN DIANA	Chief Medical Officer	37	$0	$3.22M	2021-03-10
Baker Bros. Advisors (GP) LLC	Director	1	$0	$0	2020-05-08
BAKER FELIX	Director	1	$0	$0	2020-03-16
Poon David Kai Yuen	See Remarks	4	$0	$15.4K	2019-05-06
Bedford Nick	Director	1	$0	$0	2019-05-06
LILLY ELI & CO	10% Owner	18	$0	$15.35M	2019-01-31

Trade history

Insider	Role	Code	Trade	Filed	Shares	Price	Value	Owned after
Schayowitz Adam	EVP, Head of R&D	M Exercise deriv	2026-10-09	2026-10-09	37,037	—	$0	74,074	SEC↗
Schayowitz Adam	EVP, Head of R&D	S Sale	2026-10-09	2026-10-09	13,832	$25.85	$357.6K	23,205	SEC↗
Schayowitz Adam	EVP, Head of R&D	M Exercise	2026-10-09	2026-10-09	37,037	—	$0	37,037	SEC↗
Hollywood Mark	EVP & Chief Operating Office	A Award	2026-07-06	2026-07-06	939	$22.22	$20.9K	133,852	SEC↗
Schneider Paul R	EVP, General Counsel	A Award deriv	2026-05-13	2026-05-15	119,000	—	$0	119,000	SEC↗
Schneider Paul R	EVP, General Counsel	A Award deriv	2026-05-13	2026-05-15	178,000	—	$0	178,000	SEC↗
Platshon Scott	EVP, Chief Business Officer	A Award deriv	2026-04-09	2026-04-10	47,000	—	$0	47,000	SEC↗
Platshon Scott	EVP, Chief Business Officer	A Award deriv	2026-04-09	2026-04-10	70,000	—	$0	70,000	SEC↗
Platshon Scott	EVP, Chief Business Officer	A Award deriv	2026-04-09	2026-04-10	76,000	—	$0	76,000	SEC↗
Schayowitz Adam	See Remarks	A Award deriv	2026-04-09	2026-04-10	76,000	—	$0	76,000	SEC↗
Schayowitz Adam	See Remarks	A Award deriv	2026-04-09	2026-04-10	47,000	—	$0	47,000	SEC↗
Schayowitz Adam	See Remarks	A Award deriv	2026-04-09	2026-04-10	70,000	—	$0	70,000	SEC↗
Stafford Kristin	EVP, Chief Financial Officer	A Award deriv	2026-04-06	2026-04-07	50,000	—	$0	50,000	SEC↗
Stafford Kristin	EVP, Chief Financial Officer	A Award deriv	2026-04-06	2026-04-07	119,000	—	$0	119,000	SEC↗
Stafford Kristin	EVP, Chief Financial Officer	A Award deriv	2026-04-06	2026-04-07	178,000	—	$0	178,000	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise deriv	2026-01-12	2026-01-12	64,000	—	$0	128,000	SEC↗
Galbraith Kenneth	Chair & CEO	A Award deriv	2026-01-12	2026-01-12	144,000	—	$0	144,000	SEC↗
Galbraith Kenneth	Chair & CEO	A Award deriv	2026-01-12	2026-01-12	222,000	—	$0	222,000	SEC↗
Galbraith Kenneth	Chair & CEO	A Award deriv	2026-01-12	2026-01-12	216,000	—	$0	216,000	SEC↗
Moore Paul Andrew	Chief Scientific Officer	M Exercise deriv	2026-01-12	2026-01-12	17,666	—	$0	35,334	SEC↗
Moore Paul Andrew	Chief Scientific Officer	A Award deriv	2026-01-12	2026-01-12	70,000	—	$0	70,000	SEC↗
Moore Paul Andrew	Chief Scientific Officer	A Award deriv	2026-01-12	2026-01-12	66,000	—	$0	66,000	SEC↗
Moore Paul Andrew	Chief Scientific Officer	A Award deriv	2026-01-12	2026-01-12	47,000	—	$0	47,000	SEC↗
Mahony Susan	Director	A Award deriv	2026-01-12	2026-01-12	11,500	—	$0	11,500	SEC↗
Mahony Susan	Director	A Award deriv	2026-01-12	2026-01-12	7,700	—	$0	7,700	SEC↗
Campoy Carlos	Director	A Award deriv	2026-01-12	2026-01-12	7,700	—	$0	7,700	SEC↗
Campoy Carlos	Director	A Award deriv	2026-01-12	2026-01-12	11,500	—	$0	11,500	SEC↗
Cesano Alessandra	Director	A Award deriv	2026-01-12	2026-01-12	11,500	—	$0	11,500	SEC↗
Cesano Alessandra	Director	A Award deriv	2026-01-12	2026-01-12	7,700	—	$0	7,700	SEC↗
Landry Robert E	Director	A Award deriv	2026-01-12	2026-01-12	11,500	—	$0	11,500	SEC↗
Landry Robert E	Director	A Award deriv	2026-01-12	2026-01-12	7,700	—	$0	7,700	SEC↗
Neu Kelvin	Director	A Award deriv	2026-01-12	2026-01-12	7,700	—	$0	7,700	SEC↗
Neu Kelvin	Director	A Award deriv	2026-01-12	2026-01-12	11,500	—	$0	11,500	SEC↗
Ciongoli Gregory Austin	Director	A Award deriv	2026-01-12	2026-01-12	11,500	—	$0	11,500	SEC↗
Ciongoli Gregory Austin	Director	A Award deriv	2026-01-12	2026-01-12	7,700	—	$0	7,700	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	M Exercise deriv	2026-01-12	2026-01-12	17,666	—	$0	35,334	SEC↗
Cherry Brian N	Director	A Award deriv	2026-01-12	2026-01-13	15,400	—	$0	15,400	SEC↗
Cherry Brian N	Director	A Award deriv	2026-01-12	2026-01-13	23,000	—	$0	23,000	SEC↗
Hollywood Mark	EVP & Chief Operating Office	M Exercise deriv	2026-01-12	2026-01-13	17,666	—	$0	35,334	SEC↗
Hollywood Mark	EVP & Chief Operating Office	A Award deriv	2026-01-12	2026-01-13	70,000	—	$0	70,000	SEC↗
Hollywood Mark	EVP & Chief Operating Office	A Award deriv	2026-01-12	2026-01-13	66,000	—	$0	66,000	SEC↗
Hollywood Mark	EVP & Chief Operating Office	A Award deriv	2026-01-12	2026-01-13	47,000	—	$0	47,000	SEC↗
Galbraith Kenneth	Chair & CEO	S Sale	2026-01-12	2026-01-12	30,424	$22.67	$689.7K	226,842	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise	2026-01-12	2026-01-12	64,000	—	$0	257,266	SEC↗
Moore Paul Andrew	Chief Scientific Officer	S Sale	2026-01-12	2026-01-12	9,560	$22.67	$216.7K	48,497	SEC↗
Moore Paul Andrew	Chief Scientific Officer	M Exercise	2026-01-12	2026-01-12	17,666	—	$0	58,057	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	S Sale	2026-01-12	2026-01-12	9,310	$22.67	$211.1K	26,708	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	M Exercise	2026-01-12	2026-01-12	17,666	—	$0	36,018	SEC↗
Hollywood Mark	EVP & Chief Operating Office	S Sale	2026-01-12	2026-01-13	6,120	$22.67	$138.7K	132,913	SEC↗
Hollywood Mark	EVP & Chief Operating Office	M Exercise	2026-01-12	2026-01-13	17,666	—	$0	139,033	SEC↗
PATTERSON LEONE D	EVP, Chief Bus & Fin Officer	A Award	2026-01-06	2026-01-07	459	$10.55	$4.8K	459	SEC↗
Moore Paul Andrew	Chief Scientific Officer	M Exercise deriv	2026-01-05	2026-01-05	17,168	—	$0	0	SEC↗
Moore Paul Andrew	Chief Scientific Officer	M Exercise deriv	2026-01-05	2026-01-05	20,000	—	$0	20,000	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise deriv	2026-01-05	2026-01-05	47,668	—	$0	0	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise deriv	2026-01-05	2026-01-05	66,666	—	$0	66,668	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	M Exercise deriv	2026-01-05	2026-01-05	20,000	—	$0	20,000	SEC↗
Moore Paul Andrew	Chief Scientific Officer	M Exercise	2026-01-05	2026-01-05	20,000	—	$0	51,212	SEC↗
Moore Paul Andrew	Chief Scientific Officer	M Exercise	2026-01-05	2026-01-05	17,168	—	$0	40,501	SEC↗
Moore Paul Andrew	Chief Scientific Officer	S Sale	2026-01-05	2026-01-05	9,289	$25.10	$233.2K	31,212	SEC↗
Moore Paul Andrew	Chief Scientific Officer	S Sale	2026-01-05	2026-01-05	10,821	$25.10	$271.6K	40,391	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise	2026-01-05	2026-01-05	66,666	—	$0	224,952	SEC↗
Galbraith Kenneth	Chair & CEO	S Sale	2026-01-05	2026-01-05	22,657	$25.10	$568.7K	158,286	SEC↗
Galbraith Kenneth	Chair & CEO	S Sale	2026-01-05	2026-01-05	31,686	$25.10	$795.3K	193,266	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise	2026-01-05	2026-01-05	47,668	—	$0	180,943	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	S Sale	2026-01-05	2026-01-05	10,538	$25.10	$264.5K	18,352	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	M Exercise	2026-01-05	2026-01-05	20,000	—	$0	28,890	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise deriv	2025-12-22	2025-12-22	100,000	—	$0	0	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise	2025-12-22	2025-12-22	100,000	—	$0	180,803	SEC↗
Galbraith Kenneth	Chair & CEO	S Sale	2025-12-22	2025-12-22	47,528	$27.02	$1.28M	133,275	SEC↗
Ciongoli Gregory Austin	Director	A Award	2025-08-12	2025-08-12	415,000	$12.02	$4.99M	488,500	SEC↗
Landry Robert E	Director	A Award deriv	2025-08-11	2025-08-12	62,000	—	$0	62,000	SEC↗
Ciongoli Gregory Austin	Director	A Award deriv	2025-08-11	2025-08-12	62,000	—	$0	62,000	SEC↗
NODELMAN OLEG	Director, 10% Owner	X Exercise deriv	2025-06-26	2025-06-27	5,086,521	—	$0	0	SEC↗
NODELMAN OLEG	Director, 10% Owner	F Tax w/h	2025-06-26	2025-06-27	41	$12.71	$521	22,970,388	SEC↗
NODELMAN OLEG	Director, 10% Owner	X Exercise	2025-06-26	2025-06-27	5,086,480	—	$0	22,970,388	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-05-19	2025-05-19	5,919	$11.78	$69.7K	17,883,908	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-05-15	2025-05-19	49,502	$11.43	$565.8K	17,877,989	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-04-17	2025-04-18	54,760	$11.52	$630.8K	17,828,487	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-04-16	2025-04-18	73,953	$11.16	$825.3K	17,773,727	SEC↗
NODELMAN OLEG	Director, 10% Owner	P Buy	2025-04-04	2025-04-07	196,438	$11.17	$2.19M	17,699,774	SEC↗
NODELMAN OLEG	Director, 10% Owner	P Buy	2025-04-03	2025-04-07	120,770	$11.84	$1.43M	17,503,336	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-04-02	2025-04-02	74,360	$11.85	$881.2K	17,382,566	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-04-01	2025-04-02	48,658	$11.60	$564.4K	17,308,206	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-03-31	2025-04-02	4,397	$11.75	$51.7K	17,259,548	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-03-26	2025-03-27	43,848	$12.24	$536.7K	17,255,151	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-03-25	2025-03-27	53,501	$12.91	$690.7K	17,211,303	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-03-24	2025-03-24	22,689	$13.08	$296.8K	17,157,802	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-03-21	2025-03-24	31,033	$12.78	$396.6K	17,135,113	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-03-20	2025-03-24	73,476	$12.93	$950.0K	17,104,080	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-03-19	2025-03-19	58,306	$12.64	$737.0K	17,030,604	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-03-18	2025-03-19	113,880	$12.65	$1.44M	16,972,298	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-03-17	2025-03-19	56,277	$12.23	$688.3K	16,858,418	SEC↗
NODELMAN OLEG	Director, 10% Owner	P Buy	2025-03-13	2025-03-13	468,356	$12.48	$5.85M	16,802,141	SEC↗
NODELMAN OLEG	Director, 10% Owner	P Buy	2025-03-12	2025-03-13	292,934	$12.25	$3.59M	16,333,785	SEC↗
NODELMAN OLEG	Director, 10% Owner	P Buy	2025-03-11	2025-03-13	320,690	$11.49	$3.68M	16,040,851	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-01-17	2025-01-21	19,748	$13.87	$273.9K	15,720,161	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-01-16	2025-01-21	121,681	$13.89	$1.69M	15,700,413	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-01-15	2025-01-15	39,029	$14.01	$546.8K	15,578,732	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-01-14	2025-01-15	54,500	$13.56	$739.0K	15,539,703	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-01-13	2025-01-15	74,125	$13.39	$992.5K	15,485,203	SEC↗
Galbraith Kenneth	Chair & CEO	A Award deriv	2025-01-10	2025-01-10	192,000	—	$0	192,000	SEC↗
Galbraith Kenneth	Chair & CEO	A Award deriv	2025-01-10	2025-01-10	288,000	—	$0	288,000	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	A Award deriv	2025-01-10	2025-01-10	79,000	—	$0	79,000	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	A Award deriv	2025-01-10	2025-01-10	53,000	—	$0	53,000	SEC↗
Moore Paul Andrew	Chief Scientific Officer	A Award deriv	2025-01-10	2025-01-10	79,000	—	$0	79,000	SEC↗
Moore Paul Andrew	Chief Scientific Officer	A Award deriv	2025-01-10	2025-01-10	53,000	—	$0	53,000	SEC↗
PATTERSON LEONE D	EVP, Chief Bus & Fin Officer	A Award deriv	2025-01-10	2025-01-10	79,000	—	$0	79,000	SEC↗
PATTERSON LEONE D	EVP, Chief Bus & Fin Officer	A Award deriv	2025-01-10	2025-01-10	53,000	—	$0	53,000	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-01-10	2025-01-10	204,098	$13.13	$2.68M	15,411,078	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-01-08	2025-01-10	21,021	$14.07	$295.8K	15,206,980	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	M Exercise deriv	2025-01-06	2025-01-06	20,000	—	$0	40,000	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise deriv	2025-01-06	2025-01-06	47,666	—	$0	47,668	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise deriv	2025-01-06	2025-01-06	66,666	—	$0	133,334	SEC↗
Moore Paul Andrew	Chief Scientific Officer	M Exercise deriv	2025-01-06	2025-01-06	20,000	—	$0	40,000	SEC↗
Moore Paul Andrew	Chief Scientific Officer	M Exercise deriv	2025-01-06	2025-01-06	17,166	—	$0	17,168	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	S Sale	2025-01-06	2025-01-06	11,110	$14.92	$165.8K	8,890	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	M Exercise	2025-01-06	2025-01-06	20,000	—	$0	20,000	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise	2025-01-06	2025-01-06	47,666	—	$0	71,428	SEC↗
Galbraith Kenneth	Chair & CEO	S Sale	2025-01-06	2025-01-06	33,406	$14.92	$498.4K	80,803	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise	2025-01-06	2025-01-06	66,666	—	$0	114,209	SEC↗
Galbraith Kenneth	Chair & CEO	S Sale	2025-01-06	2025-01-06	23,885	$14.92	$356.4K	47,543	SEC↗
Moore Paul Andrew	Chief Scientific Officer	M Exercise	2025-01-06	2025-01-06	17,166	—	$0	24,533	SEC↗
Moore Paul Andrew	Chief Scientific Officer	S Sale	2025-01-06	2025-01-06	9,792	$14.92	$146.1K	14,741	SEC↗
Moore Paul Andrew	Chief Scientific Officer	S Sale	2025-01-06	2025-01-06	11,408	$14.92	$170.2K	23,333	SEC↗
Moore Paul Andrew	Chief Scientific Officer	M Exercise	2025-01-06	2025-01-06	20,000	—	$0	34,741	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2025-01-02	2025-01-02	157,880	$14.78	$2.33M	15,185,959	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2024-12-31	2025-01-02	146,501	$14.57	$2.13M	15,028,079	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2024-12-30	2025-01-02	58,988	$14.47	$853.6K	14,881,578	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2024-12-27	2024-12-27	101,659	$14.49	$1.47M	14,822,590	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2024-12-26	2024-12-27	16,692	$14.38	$240.0K	14,720,931	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2024-12-24	2024-12-27	11,958	$14.12	$168.8K	14,704,239	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2024-12-23	2024-12-26	251,502	$14.25	$3.58M	14,692,281	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2024-12-20	2024-12-26	704,488	$14.08	$9.92M	14,440,779	SEC↗
EcoR1 Capital, LLC	Director, 10% Owner	P Buy	2024-12-19	2024-12-26	298,818	$13.53	$4.04M	13,736,291	SEC↗
Gallagher Neil	Director	A Award deriv	2024-12-10	2024-12-12	31,000	—	$0	31,000	SEC↗
Mahony Susan	Director	A Award deriv	2024-12-10	2024-12-12	31,000	—	$0	31,000	SEC↗
Cox Troy	Director	A Award deriv	2024-12-10	2024-12-12	31,000	—	$0	31,000	SEC↗
Davidson Nancy	Director	A Award deriv	2024-12-10	2024-12-12	31,000	—	$0	31,000	SEC↗
Neu Kelvin	Director	A Award deriv	2024-12-10	2024-12-12	31,000	—	$0	31,000	SEC↗
Cesano Alessandra	Director	A Award deriv	2024-12-10	2024-12-12	31,000	—	$0	31,000	SEC↗
Campoy Carlos	Director	A Award deriv	2024-12-10	2024-12-12	31,000	—	$0	31,000	SEC↗
Miller Derek John Michael	Director	A Award deriv	2024-12-10	2024-12-12	31,000	—	$0	31,000	SEC↗
PATTERSON LEONE D	EVP, Chief Bus & Fin Officer	A Award deriv	2024-09-01	2024-09-03	360,000	—	$0	360,000	SEC↗
Gallagher Neil	Director	A Award deriv	2024-04-02	2024-04-02	74,000	—	$0	74,000	SEC↗
Cesano Alessandra	Director	A Award deriv	2024-02-08	2024-02-09	74,000	—	$0	74,000	SEC↗
Moore Paul Andrew	Chief Scientific Officer	S Sale	2024-01-08	2024-01-08	2,339	$11.22	$26.2K	7,367	SEC↗
Astle Christopher	SVP & Chief Financial Office	S Sale	2024-01-08	2024-01-08	1,431	$11.22	$16.1K	6,503	SEC↗
Galbraith Kenneth	Chair & CEO	S Sale	2024-01-08	2024-01-08	5,706	$11.22	$64.0K	23,762	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	A Award deriv	2024-01-05	2024-01-08	90,000	—	$0	90,000	SEC↗
Smith Jeffrey T L	EVP & Chief Medical Officer	A Award deriv	2024-01-05	2024-01-08	60,000	—	$0	60,000	SEC↗
Moore Paul Andrew	Chief Scientific Officer	M Exercise deriv	2024-01-05	2024-01-08	17,166	—	$0	34,334	SEC↗
Moore Paul Andrew	Chief Scientific Officer	A Award deriv	2024-01-05	2024-01-08	90,000	—	$0	90,000	SEC↗
Moore Paul Andrew	Chief Scientific Officer	A Award deriv	2024-01-05	2024-01-08	60,000	—	$0	60,000	SEC↗
Astle Christopher	SVP & Chief Financial Office	A Award deriv	2024-01-05	2024-01-08	30,000	—	$0	30,000	SEC↗
Astle Christopher	SVP & Chief Financial Office	A Award deriv	2024-01-05	2024-01-08	50,000	—	$0	50,000	SEC↗
Astle Christopher	SVP & Chief Financial Office	M Exercise deriv	2024-01-05	2024-01-08	10,500	—	$0	21,000	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise deriv	2024-01-05	2024-01-08	47,666	—	$0	95,334	SEC↗
Galbraith Kenneth	Chair & CEO	A Award deriv	2024-01-05	2024-01-08	300,000	—	$0	300,000	SEC↗
Galbraith Kenneth	Chair & CEO	A Award deriv	2024-01-05	2024-01-08	200,000	—	$0	200,000	SEC↗
Moore Paul Andrew	Chief Scientific Officer	S Sale	2024-01-05	2024-01-08	7,460	$10.65	$79.4K	9,706	SEC↗
Moore Paul Andrew	Chief Scientific Officer	M Exercise	2024-01-05	2024-01-08	17,166	—	$0	17,166	SEC↗
Astle Christopher	SVP & Chief Financial Office	S Sale	2024-01-05	2024-01-08	4,563	$10.65	$48.6K	7,934	SEC↗
Astle Christopher	SVP & Chief Financial Office	M Exercise	2024-01-05	2024-01-08	10,500	—	$0	12,497	SEC↗
Galbraith Kenneth	Chair & CEO	S Sale	2024-01-05	2024-01-08	18,198	$10.65	$193.8K	29,468	SEC↗
Galbraith Kenneth	Chair & CEO	M Exercise	2024-01-05	2024-01-08	47,666	—	$0	47,666	SEC↗
EcoR1 Capital, LLC	10% Owner	P Buy deriv	2023-12-26	2024-12-23	5,086,521	$9.83	$50.00M	5,086,521	SEC↗
EcoR1 Capital, LLC	10% Owner	P Buy deriv	2023-12-26	2023-12-28	5,086,521	$9.83	$50.00M	5,086,521	SEC↗
Astle Christopher	SVP & Chief Financial Office	M Exercise deriv	2023-12-11	2023-12-11	1,550	—	$0	0	SEC↗
Astle Christopher	SVP & Chief Financial Office	M Exercise	2023-12-11	2023-12-11	1,550	—	$0	2,883	SEC↗
Astle Christopher	SVP & Chief Financial Office	S Sale	2023-12-11	2023-12-11	886	$9.13	$8.1K	1,997	SEC↗
Hillan Kenneth J.	Director	A Award deriv	2023-12-07	2023-12-08	37,000	—	$0	37,000	SEC↗
Davidson Nancy	Director	A Award deriv	2023-12-07	2023-12-08	74,000	—	$0	74,000	SEC↗
Miller Derek John Michael	Director	A Award deriv	2023-12-07	2023-12-08	37,000	—	$0	37,000	SEC↗
Mahony Susan	Director	A Award deriv	2023-12-07	2023-12-08	37,000	—	$0	37,000	SEC↗
Cox Troy	Director	A Award deriv	2023-12-07	2023-12-08	37,000	—	$0	37,000	SEC↗
Neu Kelvin	Director	A Award deriv	2023-12-07	2023-12-08	37,000	—	$0	37,000	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2023-12-07	2023-12-08	37,000	—	$0	37,000	SEC↗
Campoy Carlos	Director	A Award deriv	2023-12-07	2023-12-08	37,000	—	$0	37,000	SEC↗
Campoy Carlos	Director	A Award deriv	2023-06-30	2023-06-30	50,000	—	$0	50,000	SEC↗
EcoR1 Capital, LLC	10% Owner	P Buy	2023-06-16	2023-06-21	3,350,000	$8.12	$27.20M	13,437,473	SEC↗
Miller Derek John Michael	Director	A Award deriv	2023-04-10	2023-04-10	50,000	—	$0	50,000	SEC↗
EcoR1 Capital, LLC	10% Owner	P Buy	2023-03-28	2023-03-30	200,000	$8.00	$1.60M	10,087,473	SEC↗
Klompas Neil A	President & COO	M Exercise deriv	2023-03-10	2023-03-14	2,708	—	$0	2,709	SEC↗
Klompas Neil A	President & COO	M Exercise deriv	2023-03-10	2023-03-14	2,500	—	$0	0	SEC↗
Klompas Neil A	President & COO	S Sale	2023-03-10	2023-03-14	2,977	$7.83	$23.3K	17,032	SEC↗
Klompas Neil A	President & COO	M Exercise	2023-03-10	2023-03-14	2,500	—	$0	17,301	SEC↗
Klompas Neil A	President & COO	M Exercise	2023-03-10	2023-03-14	2,708	—	$0	20,009	SEC↗
EcoR1 Capital, LLC	10% Owner	P Buy	2023-01-20	2023-01-23	163,400	$9.88	$1.61M	9,887,473	SEC↗
EcoR1 Capital, LLC	10% Owner	P Buy	2023-01-19	2023-01-23	144,100	$9.49	$1.37M	9,724,073	SEC↗
EcoR1 Capital, LLC	10% Owner	P Buy	2023-01-18	2023-01-18	203,000	$10.00	$2.03M	9,579,973	SEC↗
EcoR1 Capital, LLC	10% Owner	P Buy	2023-01-17	2023-01-18	440,000	$9.80	$4.31M	9,376,973	SEC↗
EcoR1 Capital, LLC	10% Owner	P Buy	2023-01-13	2023-01-18	342,100	$9.81	$3.36M	8,936,973	SEC↗
EcoR1 Capital, LLC	10% Owner	P Buy	2023-01-11	2023-01-12	106,300	$7.87	$836.6K	8,594,873	SEC↗
EcoR1 Capital, LLC	10% Owner	P Buy	2023-01-10	2023-01-12	920,000	$7.65	$7.04M	8,488,573	SEC↗
Moore Paul Andrew	Chief Scientific Officer	A Award deriv	2023-01-05	2023-01-06	51,500	—	$0	51,500	SEC↗
Moore Paul Andrew	Chief Scientific Officer	A Award deriv	2023-01-05	2023-01-06	77,500	—	$0	77,500	SEC↗
Galbraith Kenneth	Chair & CEO	A Award deriv	2023-01-05	2023-01-06	143,000	—	$0	143,000	SEC↗
Galbraith Kenneth	Chair & CEO	A Award deriv	2023-01-05	2023-01-06	215,000	—	$0	215,000	SEC↗
Astle Christopher	SVP & Chief Financial Office	A Award deriv	2023-01-05	2023-01-06	31,500	—	$0	31,500	SEC↗
Astle Christopher	SVP & Chief Financial Office	A Award deriv	2023-01-05	2023-01-06	47,000	—	$0	47,000	SEC↗
Klompas Neil A	President & COO	A Award deriv	2023-01-05	2023-01-06	58,500	—	$0	58,500	SEC↗
Klompas Neil A	President & COO	A Award deriv	2023-01-05	2023-01-06	87,500	—	$0	87,500	SEC↗
Galbraith Kenneth	Chair & CEO	A Award deriv	2022-12-22	2022-12-23	100,000	—	$0	100,000	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2022-12-21	2022-12-23	25,000	—	$0	25,000	SEC↗
Hillan Kenneth J.	Director	A Award deriv	2022-12-21	2022-12-23	25,000	—	$0	25,000	SEC↗
Neu Kelvin	Director	A Award deriv	2022-12-21	2022-12-23	25,000	—	$0	25,000	SEC↗
Zoth Lota S.	Director	A Award deriv	2022-12-21	2022-12-23	25,000	—	$0	25,000	SEC↗
Cox Troy	Director	A Award deriv	2022-12-21	2022-12-23	25,000	—	$0	25,000	SEC↗
Mahony Susan	Director	A Award deriv	2022-12-21	2022-12-23	25,000	—	$0	25,000	SEC↗
Sacks Natalie	Director	A Award deriv	2022-12-21	2022-12-23	25,000	—	$0	25,000	SEC↗
Astle Christopher	SVP & Chief Financial Office	M Exercise deriv	2022-12-12	2022-12-14	1,550	—	$0	1,550	SEC↗
Astle Christopher	SVP & Chief Financial Office	M Exercise deriv	2022-12-12	2022-12-23	1,550	—	$0	1,550	SEC↗
Astle Christopher	SVP & Chief Financial Office	M Exercise	2022-12-12	2022-12-14	1,550	—	$0	2,220	SEC↗
Astle Christopher	SVP & Chief Financial Office	S Sale	2022-12-12	2022-12-14	887	$6.01	$5.3K	1,333	SEC↗
Astle Christopher	SVP & Chief Financial Office	M Exercise	2022-12-12	2022-12-23	1,550	—	$0	2,220	SEC↗
Astle Christopher	SVP & Chief Financial Office	S Sale	2022-12-12	2022-12-23	887	$6.01	$5.3K	1,333	SEC↗
Josephson Neil	Chief Medical Officer	M Exercise deriv	2022-11-10	2022-11-14	5,885	—	$0	11,772	SEC↗
Josephson Neil	Chief Medical Officer	M Exercise deriv	2022-11-10	2022-11-14	5,885	—	$0	11,772	SEC↗
Josephson Neil	Chief Medical Officer	M Exercise deriv	2022-11-10	2022-12-23	5,885	—	$0	11,772	SEC↗
Josephson Neil	Chief Medical Officer	S Sale	2022-11-10	2022-11-14	2,475	$8.10	$20.0K	14,449	SEC↗
Josephson Neil	Chief Medical Officer	M Exercise	2022-11-10	2022-11-14	5,885	—	$0	16,924	SEC↗
Josephson Neil	Chief Medical Officer	S Sale	2022-11-10	2022-11-14	2,475	$8.10	$20.0K	14,449	SEC↗
Josephson Neil	Chief Medical Officer	M Exercise	2022-11-10	2022-11-14	5,885	—	$0	16,924	SEC↗
Josephson Neil	Chief Medical Officer	S Sale	2022-11-10	2022-12-23	2,475	$8.10	$20.0K	14,449	SEC↗
Josephson Neil	Chief Medical Officer	M Exercise	2022-11-10	2022-12-23	5,885	—	$0	16,924	SEC↗
Redmile Group, LLC	10% Owner	A Award	2022-10-13	2022-10-17	30,481	$5.03	$153.3K	6,075,918	SEC↗
Redmile Group, LLC	10% Owner	P Buy	2022-10-13	2022-10-18	30,481	$5.03	$153.3K	6,075,918	SEC↗
Moore Paul Andrew	Chief Scientific Officer	A Award deriv	2022-07-18	2022-07-19	200,000	—	$0	200,000	SEC↗
Klompas Neil A	Chief Operating Officer	A Award	2022-07-05	2022-07-05	1,525	$4.51	$6.9K	14,801	SEC↗
Josephson Neil	Chief Medical Officer	A Award	2022-07-05	2022-07-05	1,525	$4.51	$6.9K	11,039	SEC↗
Josephson Neil	Chief Medical Officer	M Exercise deriv	2022-03-10	2022-03-11	1,666	—	$0	3,334	SEC↗
Josephson Neil	Chief Medical Officer	M Exercise deriv	2022-03-10	2022-03-11	729	—	$0	730	SEC↗
Klompas Neil A	Chief Operating Officer	M Exercise deriv	2022-03-10	2022-03-11	2,708	—	$0	5,417	SEC↗
Klompas Neil A	Chief Operating Officer	A Award deriv	2022-03-10	2022-03-11	200,000	—	$0	200,000	SEC↗
Klompas Neil A	Chief Operating Officer	M Exercise deriv	2022-03-10	2022-03-11	2,500	—	$0	2,500	SEC↗
Astle Christopher	SVP & Chief Financial Office	A Award deriv	2022-03-10	2022-03-11	125,000	—	$0	125,000	SEC↗
Josephson Neil	Chief Medical Officer	M Exercise	2022-03-10	2022-03-11	729	—	$0	7,848	SEC↗
Josephson Neil	Chief Medical Officer	M Exercise	2022-03-10	2022-03-11	1,666	—	$0	9,514	SEC↗
Klompas Neil A	Chief Operating Officer	S Sale	2022-03-10	2022-03-11	2,979	$6.88	$20.5K	13,276	SEC↗
Klompas Neil A	Chief Operating Officer	M Exercise	2022-03-10	2022-03-11	2,708	—	$0	16,255	SEC↗
Klompas Neil A	Chief Operating Officer	M Exercise	2022-03-10	2022-03-11	2,500	—	$0	13,547	SEC↗
Galbraith Kenneth	Chair, President & CEO	A Award deriv	2022-01-15	2022-01-18	500,000	—	$0	500,000	SEC↗
Klompas Neil A	Chief Operating Officer & CF	A Award	2022-01-07	2022-01-07	277	$13.94	$3.9K	11,047	SEC↗
Polverino Anthony J.	Chief Scientific Officer	A Award	2022-01-07	2022-01-07	74	$13.94	$1.0K	36,407	SEC↗
Josephson Neil	Chief Medical Officer	A Award	2022-01-07	2022-01-07	65	$13.94	$906	2,119	SEC↗
Josephson Neil	Chief Medical Officer	P Buy	2022-01-07	2022-01-11	1,400	$14.27	$20.0K	3,519	SEC↗
Josephson Neil	Chief Medical Officer	P Buy	2022-01-07	2022-01-11	3,600	$14.28	$51.4K	7,119	SEC↗
Josephson Neil	Chief Medical Officer	A Award deriv	2021-11-10	2021-11-12	105,943	—	$0	105,943	SEC↗
Josephson Neil	Chief Medical Officer	A Award deriv	2021-11-10	2021-11-12	17,657	—	$0	17,657	SEC↗
Polverino Anthony J.	Chief Scientific Officer	M Exercise deriv	2021-08-31	2021-09-02	4,900	—	$0	77,600	SEC↗
Polverino Anthony J.	Chief Scientific Officer	M Exercise	2021-08-31	2021-09-02	4,900	$15.00	$73.5K	36,333	SEC↗
Tehrani Ali	Chief Executive Officer	M Exercise deriv	2021-07-16	2021-07-16	41,191	—	$0	0	SEC↗
Tehrani Ali	Chief Executive Officer	M Exercise	2021-07-16	2021-07-16	41,191	$4.26	$175.5K	301,516	SEC↗
Tehrani Ali	Chief Executive Officer	S Sale	2021-07-16	2021-07-16	41,191	$36.00	$1.48M	260,325	SEC↗
Tehrani Ali	Chief Executive Officer	M Exercise deriv	2021-07-15	2021-07-16	3,800	—	$0	41,191	SEC↗
Tehrani Ali	Chief Executive Officer	S Sale	2021-07-15	2021-07-16	3,800	$36.00	$136.8K	260,325	SEC↗
Tehrani Ali	Chief Executive Officer	M Exercise	2021-07-15	2021-07-16	3,800	$4.27	$16.2K	264,125	SEC↗
Tehrani Ali	Chief Executive Officer	M Exercise deriv	2021-07-12	2021-07-13	12,669	—	$0	44,991	SEC↗
Tehrani Ali	Chief Executive Officer	M Exercise	2021-07-12	2021-07-13	12,669	$4.31	$54.6K	272,994	SEC↗
Tehrani Ali	Chief Executive Officer	S Sale	2021-07-12	2021-07-13	12,669	$36.12	$457.6K	260,325	SEC↗
Priour James	Chief Commercial Officer	A Award	2021-07-06	2021-07-08	510	$29.49	$15.0K	2,513	SEC↗
Josephson Neil	Interim Chief Medical Office	A Award	2021-07-06	2021-07-08	461	$29.49	$13.6K	2,054	SEC↗
Polverino Anthony J.	Chief Scientific Officer	A Award	2021-07-06	2021-07-08	454	$29.49	$13.4K	31,433	SEC↗
Klompas Neil A	Chief Financial Officer	A Award	2021-07-06	2021-07-08	299	$29.49	$8.8K	10,770	SEC↗
O'Driscoll Kathryn	Chief People Officer	A Award	2021-07-06	2021-07-08	510	$29.49	$15.0K	6,350	SEC↗
Zoth Lota S.	Director	A Award deriv	2021-05-06	2021-05-07	9,000	—	$0	9,000	SEC↗
RENTON HOLLINGS	Director	A Award deriv	2021-05-06	2021-05-07	9,000	—	$0	9,000	SEC↗
Cox Troy	Director	A Award deriv	2021-05-06	2021-05-07	9,000	—	$0	9,000	SEC↗
Sacks Natalie	Director	A Award deriv	2021-05-06	2021-05-07	9,000	—	$0	9,000	SEC↗
Mahony Susan	Director	A Award deriv	2021-05-06	2021-05-07	9,000	—	$0	9,000	SEC↗
Hillan Kenneth J.	Director	A Award deriv	2021-05-06	2021-05-07	9,000	—	$0	9,000	SEC↗
Neu Kelvin	Director	A Award deriv	2021-05-06	2021-05-07	9,000	—	$0	9,000	SEC↗
Priour James	Chief Commercial Officer	M Exercise deriv	2021-04-13	2021-04-13	2,266	—	$0	4,534	SEC↗
Priour James	Chief Commercial Officer	M Exercise	2021-04-13	2021-04-13	2,266	—	$0	2,953	SEC↗
Priour James	Chief Commercial Officer	S Sale	2021-04-13	2021-04-13	950	$27.93	$26.5K	2,003	SEC↗
O'Driscoll Kathryn	Chief People Officer	M Exercise deriv	2021-03-15	2021-03-17	837	—	$0	94,160	SEC↗
O'Driscoll Kathryn	Chief People Officer	M Exercise	2021-03-15	2021-03-17	837	$34.24	$28.7K	5,840	SEC↗
O'Driscoll Kathryn	Chief People Officer	S Sale	2021-03-15	2021-03-17	786	$34.72	$27.3K	5,003	SEC↗
HAUSMAN DIANA	Chief Medical Officer	M Exercise deriv	2021-03-10	2021-03-12	2,500	—	$0	5,000	SEC↗
HAUSMAN DIANA	Chief Medical Officer	A Award deriv	2021-03-10	2021-03-12	8,125	—	$0	8,125	SEC↗
HAUSMAN DIANA	Chief Medical Officer	A Award deriv	2021-03-10	2021-03-12	48,750	—	$0	48,750	SEC↗
Klompas Neil A	Chief Financial Officer	A Award deriv	2021-03-10	2021-03-12	8,125	—	$0	8,125	SEC↗
Klompas Neil A	Chief Financial Officer	M Exercise deriv	2021-03-10	2021-03-12	2,500	—	$0	5,000	SEC↗
Klompas Neil A	Chief Financial Officer	A Award deriv	2021-03-10	2021-03-12	48,750	—	$0	48,750	SEC↗
Polverino Anthony J.	Chief Scientific Officer	A Award deriv	2021-03-10	2021-03-12	48,750	—	$0	48,750	SEC↗
Polverino Anthony J.	Chief Scientific Officer	M Exercise deriv	2021-03-10	2021-03-12	2,500	—	$0	5,000	SEC↗
Polverino Anthony J.	Chief Scientific Officer	A Award deriv	2021-03-10	2021-03-12	8,125	—	$0	8,125	SEC↗
Tehrani Ali	Chief Executive Officer	A Award deriv	2021-03-10	2021-03-12	25,000	—	$0	25,000	SEC↗
Tehrani Ali	Chief Executive Officer	M Exercise deriv	2021-03-10	2021-03-12	7,708	—	$0	15,417	SEC↗
Tehrani Ali	Chief Executive Officer	A Award deriv	2021-03-10	2021-03-12	150,000	—	$0	150,000	SEC↗
Priour James	Chief Commercial Officer	A Award deriv	2021-03-10	2021-03-12	6,250	—	$0	6,250	SEC↗
Priour James	Chief Commercial Officer	A Award deriv	2021-03-10	2021-03-12	37,500	—	$0	37,500	SEC↗
O'Driscoll Kathryn	Chief People Officer	A Award deriv	2021-03-10	2021-03-12	5,000	—	$0	5,000	SEC↗
O'Driscoll Kathryn	Chief People Officer	A Award deriv	2021-03-10	2021-03-12	30,000	—	$0	30,000	SEC↗
O'Driscoll Kathryn	Chief People Officer	M Exercise deriv	2021-03-10	2021-03-12	1,354	—	$0	2,709	SEC↗
HAUSMAN DIANA	Chief Medical Officer	S Sale	2021-03-10	2021-03-12	1,048	$34.95	$36.6K	5,377	SEC↗
HAUSMAN DIANA	Chief Medical Officer	M Exercise	2021-03-10	2021-03-12	2,500	—	$0	6,425	SEC↗
Klompas Neil A	Chief Financial Officer	S Sale	2021-03-10	2021-03-12	1,425	$34.95	$49.8K	10,471	SEC↗
Klompas Neil A	Chief Financial Officer	M Exercise	2021-03-10	2021-03-12	2,500	—	$0	11,896	SEC↗
Polverino Anthony J.	Chief Scientific Officer	S Sale	2021-03-10	2021-03-12	1,048	$34.95	$36.6K	30,979	SEC↗